TreeWAS – Variant ID: rs2524051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.113	0.887
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.000	0.284	0.716
L40.8 Other psoriasis	0.000	0.321	0.678
E03 Other hypothyroidism	0.515	0.484	0.001
K90 Intestinal malabsorption	0.000	0.542	0.458
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.425	0.575	0.000
L40-L45 Papulosquamous disorders	0.000	0.619	0.381
E03.5 Myxoedema coma	0.369	0.630	0.001
E03.4 Atrophy of thyroid (acquired)	0.369	0.630	0.001
E03.3 Postinfectious hypothyroidism	0.369	0.630	0.001
E03.1 Congenital hypothyroidism without goitre	0.369	0.630	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.369	0.630	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.635	0.365
E03.8 Other specified hypothyroidism	0.346	0.654	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.671	0.329
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.671	0.329
K90.1 Tropical sprue	0.000	0.671	0.329
K90.8 Other intestinal malabsorption	0.000	0.681	0.319
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.697	0.303
L44 Other papulosquamous disorders	0.000	0.726	0.273
L41 Parapsoriasis	0.000	0.726	0.273
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.726	0.273
L43 Lichen planus	0.000	0.734	0.266
L42 Pityriasis rosea	0.000	0.736	0.264
L43.8 Other lichen planus	0.000	0.799	0.201
M25.5 Pain in joint	0.000	0.803	0.197
L41.9 Parapsoriasis, unspecified	0.000	0.804	0.196
L41.8 Other parapsoriasis	0.000	0.804	0.196
L41.5 Retiform parapsoriasis	0.000	0.804	0.196
L41.4 Large plaque parapsoriasis	0.000	0.804	0.196
L41.3 Small plaque parapsoriasis	0.000	0.804	0.196
L41.2 Lymphomatoid papulosis	0.000	0.804	0.196
L41.1 Pityriasis lichenoides chronica	0.000	0.804	0.196
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.804	0.196
L44.9 Papulosquamous disorder, unspecified	0.000	0.804	0.196
L44.8 Other specified papulosquamous disorders	0.000	0.804	0.196
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.804	0.196
L44.3 Lichen ruber moniliformis	0.000	0.804	0.196
L44.2 Lichen striatus	0.000	0.804	0.196
L44.1 Lichen nitidus	0.000	0.804	0.196
L44.0 Pityriasis rubra pilaris	0.000	0.804	0.196
M25.54 Pain in joint (Hand)	0.000	0.808	0.192
M25.51 Pain in joint (Shoulder region)	0.000	0.809	0.191
L43.3 Subacute (active) lichen planus	0.000	0.809	0.191
L43.2 Lichenoid drug reaction	0.000	0.809	0.191
L43.1 Bullous lichen planus	0.000	0.809	0.191
L43.0 Hypertrophic lichen planus	0.000	0.809	0.191
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.816	0.184
M25.59 Pain in joint (Site unspecified)	0.000	0.828	0.172
L43.9 Lichen planus, unspecified	0.000	0.830	0.170
M25.58 Pain in joint (Other)	0.000	0.838	0.162
M25 Other joint disorders, not elsewhere classified	0.000	0.849	0.151
M25.53 Pain in joint (Forearm)	0.000	0.863	0.137
M25.9 Joint disorder, unspecified	0.000	0.865	0.135
M25.56 Pain in joint (Lower leg)	0.000	0.865	0.135
M25.57 Pain in joint (Ankle and foot)	0.000	0.865	0.135
M25.50 Pain in joint (Multiple sites)	0.000	0.867	0.133
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.868	0.132
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.874	0.126
M25.52 Pain in joint (Upper arm)	0.000	0.876	0.124
M25.7 Osteophyte	0.000	0.876	0.124
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.876	0.124
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.890	0.110
M25.8 Other specified joint disorders	0.000	0.892	0.108
M25.2 Flail joint	0.000	0.892	0.108
M25.1 Fistula of joint	0.000	0.892	0.108
M25.71 Osteophyte (Shoulder region)	0.000	0.895	0.105
M25.0 Haemarthrosis	0.000	0.897	0.103
M25.77 Osteophyte (Ankle and foot)	0.000	0.897	0.103
M25.74 Osteophyte (Hand)	0.000	0.897	0.103
M25.84 Other specified joint disorders (Hand)	0.000	0.900	0.100
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.902	0.098
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.903	0.097
M25.98 Joint disorder, unspecified (Other)	0.000	0.903	0.097
M25.94 Joint disorder, unspecified (Hand)	0.000	0.903	0.097
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.903	0.097
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.903	0.097
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.903	0.097
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.903	0.097
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.904	0.096
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.905	0.095
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.905	0.095
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.905	0.095
M25.76 Osteophyte (Lower leg)	0.000	0.906	0.094
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.907	0.093
M25.3 Other instability of joint	0.000	0.909	0.091
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.910	0.089
M25.79 Osteophyte (Site unspecified)	0.000	0.911	0.089
M25.73 Osteophyte (Forearm)	0.000	0.911	0.089
M25.70 Osteophyte (Multiple sites)	0.000	0.911	0.089
M25.72 Osteophyte (Upper arm)	0.000	0.911	0.089
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.914	0.086
M25.86 Other specified joint disorders (Lower leg)	0.000	0.914	0.086
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.921	0.079
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.921	0.079
M25.4 Effusion of joint	0.000	0.921	0.079
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.922	0.078
M25.82 Other specified joint disorders (Upper arm)	0.000	0.922	0.078
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.922	0.078
M25.19 Fistula of joint (Site unspecified)	0.000	0.922	0.078
M25.18 Fistula of joint (Other)	0.000	0.922	0.078
M25.17 Fistula of joint (Ankle and foot)	0.000	0.922	0.078
M25.16 Fistula of joint (Lower leg)	0.000	0.922	0.078
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.922	0.078
M25.14 Fistula of joint (Hand)	0.000	0.922	0.078
M25.13 Fistula of joint (Forearm)	0.000	0.922	0.078
M25.12 Fistula of joint (Upper arm)	0.000	0.922	0.078
M25.11 Fistula of joint (Shoulder region)	0.000	0.922	0.078
M25.10 Fistula of joint (Multiple sites)	0.000	0.922	0.078
M25.29 Flail joint (Site unspecified)	0.000	0.922	0.078
M25.28 Flail joint (Other)	0.000	0.922	0.078
M25.27 Flail joint (Ankle and foot)	0.000	0.922	0.078
M25.26 Flail joint (Lower leg)	0.000	0.922	0.078
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.922	0.078
M25.24 Flail joint (Hand)	0.000	0.922	0.078
M25.23 Flail joint (Forearm)	0.000	0.922	0.078
M25.22 Flail joint (Upper arm)	0.000	0.922	0.078
M25.21 Flail joint (Shoulder region)	0.000	0.922	0.078
M25.20 Flail joint (Multiple sites)	0.000	0.922	0.078
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.924	0.076
M25.09 Haemarthrosis (Site unspecified)	0.000	0.926	0.074
M25.08 Haemarthrosis (Other)	0.000	0.926	0.074
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.926	0.074
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.926	0.074
M25.04 Haemarthrosis (Hand)	0.000	0.926	0.074
M25.03 Haemarthrosis (Forearm)	0.000	0.926	0.074
M25.02 Haemarthrosis (Upper arm)	0.000	0.926	0.074
M25.01 Haemarthrosis (Shoulder region)	0.000	0.926	0.074
M25.00 Haemarthrosis (Multiple sites)	0.000	0.926	0.074
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.928	0.072
I84.9 Unspecified haemorrhoids without complication	0.072	0.928	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.931	0.069
M25.06 Haemarthrosis (Lower leg)	0.000	0.931	0.069
M25.83 Other specified joint disorders (Forearm)	0.000	0.931	0.069
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.932	0.068
M25.46 Effusion of joint (Lower leg)	0.000	0.933	0.067
M25.36 Other instability of joint (Lower leg)	0.000	0.934	0.066
M25.39 Other instability of joint (Site unspecified)	0.000	0.935	0.065
M25.38 Other instability of joint (Other)	0.000	0.935	0.065
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.935	0.065
M25.32 Other instability of joint (Upper arm)	0.000	0.935	0.065
M25.30 Other instability of joint (Multiple sites)	0.000	0.935	0.065
M25.88 Other specified joint disorders (Other)	0.000	0.938	0.062
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.938	0.062
M25.43 Effusion of joint (Forearm)	0.000	0.938	0.061
M25.31 Other instability of joint (Shoulder region)	0.000	0.940	0.060
M25.34 Other instability of joint (Hand)	0.000	0.942	0.058
M25.33 Other instability of joint (Forearm)	0.000	0.943	0.057
M25.49 Effusion of joint (Site unspecified)	0.000	0.943	0.057
M25.48 Effusion of joint (Other)	0.000	0.943	0.057
M25.41 Effusion of joint (Shoulder region)	0.000	0.943	0.057
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.948	0.052
M25.42 Effusion of joint (Upper arm)	0.000	0.950	0.050
M25.44 Effusion of joint (Hand)	0.000	0.951	0.049
M25.40 Effusion of joint (Multiple sites)	0.000	0.952	0.048
M25.78 Osteophyte (Other)	0.000	0.953	0.047
K90-K93 Other diseases of the digestive system	0.000	0.964	0.036
M25.47 Effusion of joint (Ankle and foot)	0.000	0.964	0.035
E00-E07 Disorders of thyroid gland	0.033	0.965	0.002
E07 Other disorders of thyroid	0.028	0.971	0.001
M20-M25 Other joint disorders	0.000	0.972	0.028
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.974	0.026
M24 Other specific joint derangements	0.000	0.974	0.026
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.024	0.975	0.002
E00 Congenital iodine-deficiency syndrome	0.024	0.975	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.024	0.975	0.002
E07.9 Disorder of thyroid, unspecified	0.025	0.975	0.000
M21 Other acquired deformities of limbs	0.000	0.975	0.025
M24.0 Loose body in joint	0.000	0.977	0.023
M31 Other necrotising vasculopathies	0.000	0.977	0.023
M24.1 Other articular cartilage disorders	0.000	0.977	0.023
M32 Systemic lupus erythematosus	0.000	0.977	0.023
M30 Polyarteritis nodosa and related conditions	0.000	0.978	0.022
M34 Systemic sclerosis	0.000	0.978	0.022
M21.1 Varus deformity, not elsewhere classified	0.000	0.978	0.022
M24.02 Loose body in joint (Upper arm)	0.000	0.979	0.021
M21.3 Wrist or foot drop (acquired)	0.000	0.979	0.021
E07.1 Dyshormogenetic goitre	0.020	0.979	0.001
E07.0 Hypersecretion of calcitonin	0.020	0.979	0.001
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.979	0.021
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.979	0.021
M31.6 Other giant cell arteritis	0.000	0.979	0.020
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.980	0.020
M24.01 Loose body in joint (Shoulder region)	0.000	0.980	0.020
M33 Dermatopolymyositis	0.000	0.980	0.019
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.981	0.019
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.981	0.019
M24.2 Disorder of ligament	0.000	0.981	0.019
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.981	0.019
K93.1 Megacolon in Chagas' disease	0.000	0.981	0.019
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.981	0.019
M21.0 Valgus deformity, not elsewhere classified	0.000	0.981	0.019
M24.6 Ankylosis of joint	0.000	0.981	0.019
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.981	0.019
S64.4 Injury of digital nerve of other finger	0.019	0.981	0.000
E07.8 Other specified disorders of thyroid	0.018	0.981	0.001
M24.9 Joint derangement, unspecified	0.000	0.981	0.019
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.981	0.018
M21.4 Flat foot [pes planus] (acquired)	0.000	0.982	0.018
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.017	0.982	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.017	0.982	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.017	0.982	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.017	0.982	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.017	0.982	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.017	0.982	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.017	0.982	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.017	0.982	0.001
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.982	0.018
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.982	0.018
D75 Other diseases of blood and blood-forming organs	0.000	0.982	0.018
M21.9 Acquired deformity of limb, unspecified	0.000	0.982	0.018
M21.8 Other specified acquired deformities of limbs	0.000	0.982	0.018
M21.7 Unequal limb length (acquired)	0.000	0.982	0.018
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.982	0.018
M34.9 Systemic sclerosis, unspecified	0.000	0.983	0.017
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.983	0.017
D70 Agranulocytosis	0.000	0.983	0.017
M24.09 Loose body in joint (Site unspecified)	0.000	0.983	0.017
M24.08 Loose body in joint (Other)	0.000	0.983	0.017
M24.06 Loose body in joint-Lower leg	0.000	0.983	0.017
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.983	0.017
M24.04 Loose body in joint (Hand)	0.000	0.983	0.017
M24.03 Loose body in joint (Forearm)	0.000	0.983	0.017
M24.00 Loose body in joint (Multiple sites)	0.000	0.983	0.017
M31.8 Other specified necrotising vasculopathies	0.000	0.983	0.017
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.983	0.017
M31.2 Lethal midline granuloma	0.000	0.983	0.017
M31.1 Thrombotic microangiopathy	0.000	0.983	0.017
M31.0 Hypersensitivity angiitis	0.000	0.983	0.017
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.983	0.017
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.983	0.017
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.983	0.017
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.983	0.017
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.983	0.017
M24.18 Other articular cartilage disorders (Other)	0.000	0.983	0.017
M24.14 Other articular cartilage disorders (Hand)	0.000	0.983	0.017
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.983	0.017
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.983	0.017
M21.6 Other acquired deformities of ankle and foot	0.000	0.983	0.017
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.983	0.016
M32.8 Other forms of systemic lupus erythematosus	0.000	0.983	0.016
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.983	0.016
M24.7 Protrusio acetabuli	0.000	0.984	0.016
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.984	0.016
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.984	0.016
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.984	0.016
M31.3 Wegener's granulomatosis	0.000	0.984	0.016
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.984	0.016
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.984	0.016
M30.2 Juvenile polyarteritis	0.000	0.984	0.016
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.984	0.016
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.984	0.016
M34.8 Other forms of systemic sclerosis	0.000	0.984	0.016
D75.2 Essential thrombocytosis	0.000	0.984	0.016
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.984	0.016
M34.0 Progressive systemic sclerosis	0.000	0.984	0.016
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.984	0.016
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.984	0.016
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.984	0.016
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.984	0.016
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.984	0.016
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.984	0.016
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.984	0.016
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.984	0.016
M24.23 Disorder of ligament (Forearm)	0.000	0.984	0.016
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.984	0.016
E06 Thyroiditis	0.014	0.984	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.984	0.015
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.984	0.016
M30.0 Polyarteritis nodosa	0.000	0.984	0.015
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.985	0.015
D73 Diseases of spleen	0.000	0.985	0.015
D72 Other disorders of white blood cells	0.000	0.985	0.015
M35 Other systemic involvement of connective tissue	0.000	0.985	0.015
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.985	0.015
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.985	0.015
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.985	0.015
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.985	0.015
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.985	0.015
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.985	0.015
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.985	0.015
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.985	0.015
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.985	0.015
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.985	0.015
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.985	0.015
M36.3 Arthropathy in other blood disorders	0.000	0.985	0.015
M36.2 Haemophilic arthropathy	0.000	0.985	0.015
M36.1 Arthropathy in neoplastic disease	0.000	0.985	0.015
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.985	0.015
M24.5 Contracture of joint	0.000	0.985	0.015
M31.9 Necrotising vasculopathy, unspecified	0.000	0.985	0.015
M31.7 Microscopic polyangiitis	0.000	0.985	0.015
M34.1 CR(E)ST syndrome	0.000	0.985	0.015
M24.21 Disorder of ligament (Shoulder region)	0.000	0.985	0.015
M33.2 Polymyositis	0.000	0.985	0.015
M24.07 Loose body in joint (Ankle and foot)	0.000	0.985	0.015
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.985	0.015
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.985	0.015
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.985	0.015
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.985	0.015
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.985	0.015
D72.8 Other specified disorders of white blood cells	0.000	0.985	0.014
D12.8 Rectum	0.014	0.986	0.000
D73.0 Hyposplenism	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.000	0.986	0.014
M21.2 Flexion deformity	0.000	0.986	0.014
M33.9 Dermatopolymyositis, unspecified	0.000	0.986	0.014
M33.0 Juvenile dermatomyositis	0.000	0.986	0.014
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.986	0.014
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.986	0.014
M24.29 Disorder of ligament (Site unspecified)	0.000	0.986	0.014
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.986	0.014
M24.22 Disorder of ligament (Upper arm)	0.000	0.986	0.014
M24.20 Disorder of ligament (Multiple sites)	0.000	0.986	0.014
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.986	0.014
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.986	0.014
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.986	0.014
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.986	0.014
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.986	0.014
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.986	0.014
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.986	0.014
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.986	0.014
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.986	0.014
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.986	0.014
M24.68 Ankylosis of joint (Other)	0.000	0.986	0.014
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.986	0.014
M24.64 Ankylosis of joint (Hand)	0.000	0.986	0.014
M24.63 Ankylosis of joint (Forearm)	0.000	0.986	0.014
M24.62 Ankylosis of joint (Upper arm)	0.000	0.986	0.014
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.986	0.014
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.986	0.014
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.986	0.013
M24.98 Joint derangement, unspecified (Other)	0.000	0.986	0.013
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.986	0.013
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.986	0.013
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.986	0.013
M24.94 Joint derangement, unspecified (Hand)	0.000	0.986	0.013
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.986	0.013
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.986	0.013
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.986	0.013
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.986	0.013
M24.66 Ankylosis of joint (Lower leg)	0.000	0.986	0.013
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.987	0.013
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.987	0.013
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.987	0.013
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.987	0.013
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.987	0.013
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.987	0.013
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.987	0.013
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.987	0.013
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.987	0.013
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.987	0.013
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.987	0.013
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.987	0.013
M21.78 Unequal limb length (acquired)-Other	0.000	0.987	0.013
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.987	0.013
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.987	0.013
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.987	0.013
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.987	0.013
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.987	0.013
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.987	0.013
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.987	0.013
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.987	0.013
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.987	0.013
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.987	0.013
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.987	0.013
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.987	0.013
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.987	0.013
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.987	0.013
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.987	0.013
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.987	0.013
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.987	0.013
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.987	0.013
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.987	0.013
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.987	0.013
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.987	0.013
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.987	0.013
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.987	0.013
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.987	0.013
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.987	0.013
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.987	0.013
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.987	0.013
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.987	0.013
D74 Methaemoglobinaemia	0.000	0.987	0.013
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.987	0.013
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.987	0.013
M24.24 Disorder of ligament (Hand)	0.000	0.987	0.013
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.987	0.013
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.987	0.012
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.987	0.012
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.987	0.012
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.987	0.012
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.987	0.012
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.987	0.012
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.987	0.012
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.988	0.012
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.988	0.012
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.988	0.012
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.988	0.012
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.988	0.012
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.988	0.012
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.988	0.012
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.988	0.012
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.988	0.012
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.988	0.012
D75.0 Familial erythrocytosis	0.000	0.988	0.012
M33.1 Other dermatomyositis	0.000	0.988	0.012
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.988	0.012
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.988	0.012
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.988	0.012
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.988	0.012
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.988	0.012
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.988	0.012
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.988	0.012
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.988	0.012
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.988	0.012
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.988	0.012
M24.28 Disorder of ligament (Other)	0.000	0.988	0.012
M24.79 Protrusio acetabuli-Site unspec	0.000	0.988	0.012
M24.78 Protrusio acetabuli-Other	0.000	0.988	0.012
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.988	0.012
M24.76 Protrusio acetabuli-Lower leg	0.000	0.988	0.012
M24.74 Protrusio acetabuli-Hand	0.000	0.988	0.012
M24.73 Protrusio acetabuli-Forearm	0.000	0.988	0.012
M24.72 Protrusio acetabuli-Upper arm	0.000	0.988	0.012
M24.71 Protrusio acetabuli-Shldr region	0.000	0.988	0.012
M24.70 Protrusio acetabuli-Mult sites	0.000	0.988	0.012
S64 Injury of nerves at wrist and hand level	0.012	0.988	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.988	0.012
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.988	0.012
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.988	0.012
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.988	0.012
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.988	0.012
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.988	0.012
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.988	0.012
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.988	0.012
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.988	0.012
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.000	0.988	0.012
M35.3 Polymyalgia rheumatica	0.000	0.988	0.012
M35.7 Hypermobility syndrome	0.000	0.988	0.011
E06.5 Other chronic thyroiditis	0.010	0.989	0.002
E06.4 Drug-induced thyroiditis	0.010	0.989	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.010	0.989	0.002
E06.1 Subacute thyroiditis	0.010	0.989	0.002
E06.0 Acute thyroiditis	0.010	0.989	0.002
C18.7 Sigmoid colon	0.011	0.989	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.989	0.011
D72.0 Genetic anomalies of leukocytes	0.000	0.989	0.011
D73.9 Disease of spleen, unspecified	0.000	0.989	0.011
D73.8 Other diseases of spleen	0.000	0.989	0.011
D73.4 Cyst of spleen	0.000	0.989	0.011
D73.3 Abscess of spleen	0.000	0.989	0.011
D73.2 Chronic congestive splenomegaly	0.000	0.989	0.011
D73.1 Hypersplenism	0.000	0.989	0.011
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.989	0.011
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.989	0.011
M35.5 Multifocal fibrosclerosis	0.000	0.989	0.011
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.989	0.011
R47.0 Dysphasia and aphasia	0.000	0.989	0.011
M24.59 Contracture of joint (Site unspecified)	0.000	0.989	0.011
M24.58 Contracture of joint (Other)	0.000	0.989	0.011
M24.57 Contracture of joint (Ankle and foot)	0.000	0.989	0.011
M24.53 Contracture of joint (Forearm)	0.000	0.989	0.011
M24.52 Contracture of joint (Upper arm)	0.000	0.989	0.011
M24.50 Contracture of joint (Multiple sites)	0.000	0.989	0.011
M35.8 Other specified systemic involvement of connective tissue	0.000	0.989	0.011
M24.51 Contracture of joint (Shoulder region)	0.000	0.989	0.011
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.989	0.011
M35.2 Behcet's disease	0.000	0.989	0.011
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.989	0.010
M24.54 Contracture of joint (Hand)	0.000	0.989	0.011
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.989	0.010
M21.29 Flexion deformity (Site unspecified)	0.000	0.989	0.010
M21.28 Flexion deformity (Other)	0.000	0.989	0.010
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.989	0.010
M21.23 Flexion deformity (Forearm)	0.000	0.989	0.010
M21.22 Flexion deformity (Upper arm)	0.000	0.989	0.010
M21.21 Flexion deformity (Shoulder region)	0.000	0.989	0.010
M21.20 Flexion deformity (Multiple sites)	0.000	0.989	0.010
E66.8 Other obesity	0.000	0.990	0.010
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.990	0.010
M24.26 Disorder of ligament (Lower leg)	0.000	0.990	0.010
M22 Disorders of patella	0.000	0.990	0.010
C71.9 Brain, unspecified	0.010	0.990	0.000
M21.24 Flexion deformity (Hand)	0.000	0.990	0.010
D76.3 Other histiocytosis syndromes	0.000	0.990	0.010
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.990	0.010
I47.2 Ventricular tachycardia	0.010	0.990	0.000
R94.3 Abnormal results of cardiovascular function studies	0.010	0.990	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.010	0.990	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.990	0.009
D73.5 Infarction of spleen	0.000	0.990	0.010

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations