TreeWAS – Variant ID: rs2524132

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.107	0.893
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.000	0.284	0.716
L40.8 Other psoriasis	0.000	0.323	0.677
E03 Other hypothyroidism	0.529	0.471	0.000
K90 Intestinal malabsorption	0.000	0.528	0.472
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.441	0.559	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.618	0.382
E03.5 Myxoedema coma	0.379	0.620	0.000
E03.4 Atrophy of thyroid (acquired)	0.379	0.620	0.000
E03.3 Postinfectious hypothyroidism	0.379	0.620	0.000
E03.1 Congenital hypothyroidism without goitre	0.379	0.620	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.379	0.620	0.000
E03.8 Other specified hypothyroidism	0.356	0.643	0.000
L40-L45 Papulosquamous disorders	0.000	0.648	0.352
K90.3 Pancreatic steatorrhoea	0.000	0.661	0.339
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.661	0.339
K90.1 Tropical sprue	0.000	0.661	0.339
K90.8 Other intestinal malabsorption	0.000	0.667	0.332
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.693	0.307
L44 Other papulosquamous disorders	0.000	0.747	0.253
L41 Parapsoriasis	0.000	0.747	0.253
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.747	0.253
L42 Pityriasis rosea	0.000	0.756	0.243
L43 Lichen planus	0.000	0.768	0.232
L41.9 Parapsoriasis, unspecified	0.000	0.818	0.181
L41.8 Other parapsoriasis	0.000	0.818	0.181
L41.5 Retiform parapsoriasis	0.000	0.818	0.181
L41.4 Large plaque parapsoriasis	0.000	0.818	0.181
L41.3 Small plaque parapsoriasis	0.000	0.818	0.181
L41.2 Lymphomatoid papulosis	0.000	0.818	0.181
L41.1 Pityriasis lichenoides chronica	0.000	0.818	0.181
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.818	0.181
L44.9 Papulosquamous disorder, unspecified	0.000	0.818	0.181
L44.8 Other specified papulosquamous disorders	0.000	0.818	0.181
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.818	0.181
L44.3 Lichen ruber moniliformis	0.000	0.818	0.181
L44.2 Lichen striatus	0.000	0.818	0.181
L44.1 Lichen nitidus	0.000	0.818	0.181
L44.0 Pityriasis rubra pilaris	0.000	0.818	0.181
L43.8 Other lichen planus	0.000	0.825	0.175
L43.3 Subacute (active) lichen planus	0.000	0.833	0.166
L43.2 Lichenoid drug reaction	0.000	0.833	0.166
L43.1 Bullous lichen planus	0.000	0.833	0.166
L43.0 Hypertrophic lichen planus	0.000	0.833	0.166
L43.9 Lichen planus, unspecified	0.000	0.867	0.133
M25.5 Pain in joint	0.000	0.936	0.064
M25.54 Pain in joint (Hand)	0.000	0.937	0.063
M25.51 Pain in joint (Shoulder region)	0.000	0.939	0.061
I84.9 Unspecified haemorrhoids without complication	0.060	0.940	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.943	0.057
M25.59 Pain in joint (Site unspecified)	0.000	0.944	0.056
M25.58 Pain in joint (Other)	0.000	0.948	0.052
M25.57 Pain in joint (Ankle and foot)	0.000	0.953	0.047
M25.56 Pain in joint (Lower leg)	0.000	0.955	0.045
M25.53 Pain in joint (Forearm)	0.000	0.957	0.043
M25 Other joint disorders, not elsewhere classified	0.000	0.958	0.042
M25.50 Pain in joint (Multiple sites)	0.000	0.958	0.042
M25.52 Pain in joint (Upper arm)	0.000	0.960	0.039
K90-K93 Other diseases of the digestive system	0.000	0.961	0.039
M25.9 Joint disorder, unspecified	0.000	0.962	0.037
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.963	0.037
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.964	0.036
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.966	0.034
E00-E07 Disorders of thyroid gland	0.032	0.966	0.002
M25.7 Osteophyte	0.000	0.966	0.034
M25.8 Other specified joint disorders	0.000	0.969	0.031
D12.8 Rectum	0.031	0.969	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.969	0.031
M25.2 Flail joint	0.000	0.970	0.030
M25.1 Fistula of joint	0.000	0.970	0.030
M25.84 Other specified joint disorders (Hand)	0.000	0.971	0.029
M25.74 Osteophyte (Hand)	0.000	0.971	0.029
M25.71 Osteophyte (Shoulder region)	0.000	0.971	0.029
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.972	0.028
E07 Other disorders of thyroid	0.027	0.972	0.001
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.973	0.027
M25.0 Haemarthrosis	0.000	0.973	0.027
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.973	0.027
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.973	0.027
M25.98 Joint disorder, unspecified (Other)	0.000	0.973	0.027
M25.94 Joint disorder, unspecified (Hand)	0.000	0.973	0.027
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.973	0.027
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.973	0.027
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.973	0.027
M25.77 Osteophyte (Ankle and foot)	0.000	0.973	0.027
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.973	0.027
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.973	0.027
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.973	0.027
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.973	0.027
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.974	0.026
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.975	0.025
M25.3 Other instability of joint	0.000	0.975	0.025
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.023	0.975	0.001
E00 Congenital iodine-deficiency syndrome	0.023	0.975	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.023	0.975	0.001
M25.86 Other specified joint disorders (Lower leg)	0.000	0.975	0.025
M25.76 Osteophyte (Lower leg)	0.000	0.976	0.024
M25.79 Osteophyte (Site unspecified)	0.000	0.976	0.024
M25.73 Osteophyte (Forearm)	0.000	0.976	0.024
M25.70 Osteophyte (Multiple sites)	0.000	0.976	0.024
E07.9 Disorder of thyroid, unspecified	0.024	0.976	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.976	0.024
M25.72 Osteophyte (Upper arm)	0.000	0.976	0.024
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.978	0.022
M25.82 Other specified joint disorders (Upper arm)	0.000	0.978	0.022
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.978	0.022
C18.7 Sigmoid colon	0.022	0.978	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.978	0.022
M25.19 Fistula of joint (Site unspecified)	0.000	0.978	0.022
M25.18 Fistula of joint (Other)	0.000	0.978	0.022
M25.17 Fistula of joint (Ankle and foot)	0.000	0.978	0.022
M25.16 Fistula of joint (Lower leg)	0.000	0.978	0.022
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.978	0.022
M25.14 Fistula of joint (Hand)	0.000	0.978	0.022
M25.13 Fistula of joint (Forearm)	0.000	0.978	0.022
M25.12 Fistula of joint (Upper arm)	0.000	0.978	0.022
M25.11 Fistula of joint (Shoulder region)	0.000	0.978	0.022
M25.10 Fistula of joint (Multiple sites)	0.000	0.978	0.022
M25.29 Flail joint (Site unspecified)	0.000	0.978	0.022
M25.28 Flail joint (Other)	0.000	0.978	0.022
M25.27 Flail joint (Ankle and foot)	0.000	0.978	0.022
M25.26 Flail joint (Lower leg)	0.000	0.978	0.022
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.978	0.022
M25.24 Flail joint (Hand)	0.000	0.978	0.022
M25.23 Flail joint (Forearm)	0.000	0.978	0.022
M25.22 Flail joint (Upper arm)	0.000	0.978	0.022
M25.21 Flail joint (Shoulder region)	0.000	0.978	0.022
M25.20 Flail joint (Multiple sites)	0.000	0.978	0.022
M25.4 Effusion of joint	0.000	0.978	0.022
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.979	0.021
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.979	0.021
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.980	0.020
K93.1 Megacolon in Chagas' disease	0.000	0.980	0.020
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.980	0.020
E07.1 Dyshormogenetic goitre	0.019	0.980	0.001
E07.0 Hypersecretion of calcitonin	0.019	0.980	0.001
M25.09 Haemarthrosis (Site unspecified)	0.000	0.980	0.020
M25.08 Haemarthrosis (Other)	0.000	0.980	0.020
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.980	0.020
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.980	0.020
M25.04 Haemarthrosis (Hand)	0.000	0.980	0.020
M25.03 Haemarthrosis (Forearm)	0.000	0.980	0.020
M25.02 Haemarthrosis (Upper arm)	0.000	0.980	0.020
M25.01 Haemarthrosis (Shoulder region)	0.000	0.980	0.020
M25.00 Haemarthrosis (Multiple sites)	0.000	0.980	0.020
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.980	0.020
M25.83 Other specified joint disorders (Forearm)	0.000	0.980	0.020
M25.37 Other instability of joint (Ankle and foot)	0.000	0.981	0.019
M25.46 Effusion of joint (Lower leg)	0.000	0.981	0.019
M25.36 Other instability of joint (Lower leg)	0.000	0.981	0.018
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.981	0.018
M25.39 Other instability of joint (Site unspecified)	0.000	0.982	0.018
M25.38 Other instability of joint (Other)	0.000	0.982	0.018
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.982	0.018
M25.32 Other instability of joint (Upper arm)	0.000	0.982	0.018
M25.30 Other instability of joint (Multiple sites)	0.000	0.982	0.018
E07.8 Other specified disorders of thyroid	0.017	0.982	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.017	0.982	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.017	0.982	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.017	0.982	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.017	0.982	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.017	0.982	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.017	0.982	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.017	0.982	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.017	0.982	0.001
M25.88 Other specified joint disorders (Other)	0.000	0.982	0.017
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.982	0.017
M25.43 Effusion of joint (Forearm)	0.000	0.983	0.017
M25.31 Other instability of joint (Shoulder region)	0.000	0.983	0.017
M25.06 Haemarthrosis (Lower leg)	0.000	0.983	0.016
M25.34 Other instability of joint (Hand)	0.000	0.984	0.016
M25.33 Other instability of joint (Forearm)	0.000	0.984	0.016
M25.49 Effusion of joint (Site unspecified)	0.000	0.984	0.016
M25.48 Effusion of joint (Other)	0.000	0.984	0.016
M25.41 Effusion of joint (Shoulder region)	0.000	0.984	0.016
E06 Thyroiditis	0.013	0.985	0.002
D75 Other diseases of blood and blood-forming organs	0.000	0.985	0.015
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.985	0.014
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.986	0.014
M25.44 Effusion of joint (Hand)	0.000	0.986	0.014
M25.42 Effusion of joint (Upper arm)	0.000	0.986	0.014
D70 Agranulocytosis	0.000	0.986	0.014
M25.78 Osteophyte (Other)	0.000	0.986	0.014
M25.40 Effusion of joint (Multiple sites)	0.000	0.986	0.013
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.987	0.013
C18 Malignant neoplasm of colon	0.013	0.987	0.000
D75.2 Essential thrombocytosis	0.000	0.987	0.013
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.987	0.013
I47.2 Ventricular tachycardia	0.013	0.987	0.000
I47 Paroxysmal tachycardia	0.012	0.988	0.000
D72 Other disorders of white blood cells	0.000	0.988	0.012
I47.1 Supraventricular tachycardia	0.012	0.988	0.000
D73 Diseases of spleen	0.000	0.988	0.012
D75.1 Secondary polycythaemia	0.000	0.988	0.012
D72.8 Other specified disorders of white blood cells	0.000	0.988	0.012
I47.9 Paroxysmal tachycardia, unspecified	0.012	0.988	0.000
C18.1 Appendix	0.012	0.988	0.000
D73.0 Hyposplenism	0.000	0.989	0.011
E06.5 Other chronic thyroiditis	0.010	0.989	0.001
E06.4 Drug-induced thyroiditis	0.010	0.989	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.010	0.989	0.001
E06.1 Subacute thyroiditis	0.010	0.989	0.001
E06.0 Acute thyroiditis	0.010	0.989	0.001
C18.6 Descending colon	0.011	0.989	0.000
C18.0 Caecum	0.011	0.989	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.989	0.011
C18.2 Ascending colon	0.011	0.989	0.000
D74 Methaemoglobinaemia	0.000	0.989	0.010
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.989	0.010
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.989	0.010
S64.4 Injury of digital nerve of other finger	0.011	0.989	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.989	0.010
C18.3 Hepatic flexure	0.010	0.990	0.000
C18.5 Splenic flexure	0.010	0.990	0.000
D75.0 Familial erythrocytosis	0.000	0.990	0.010
M25.47 Effusion of joint (Ankle and foot)	0.000	0.990	0.010
R47.0 Dysphasia and aphasia	0.000	0.990	0.010
I47.0 Reentry ventricular arrhythmia	0.010	0.990	0.000
C18.8 Overlapping lesion of colon	0.010	0.990	0.000
D12.5 Sigmoid colon	0.009	0.991	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.991	0.009
D72.0 Genetic anomalies of leukocytes	0.000	0.991	0.009
D73.9 Disease of spleen, unspecified	0.000	0.991	0.009
D73.8 Other diseases of spleen	0.000	0.991	0.009
D73.4 Cyst of spleen	0.000	0.991	0.009
D73.3 Abscess of spleen	0.000	0.991	0.009
D73.2 Chronic congestive splenomegaly	0.000	0.991	0.009
D73.1 Hypersplenism	0.000	0.991	0.009
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.009	0.991	0.000
D12.7 Rectosigmoid junction	0.009	0.991	0.000
C71.9 Brain, unspecified	0.009	0.991	0.000
D41.4 Bladder	0.009	0.991	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.991	0.008
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.992	0.008
E66.8 Other obesity	0.000	0.992	0.008
E06.3 Autoimmune thyroiditis	0.007	0.992	0.001
D76.3 Other histiocytosis syndromes	0.000	0.992	0.008
R03.1 Nonspecific low blood-pressure reading	0.000	0.992	0.008
C77.2 Intra-abdominal lymph nodes	0.008	0.992	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.992	0.008
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.992	0.008
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.992	0.008
D73.5 Infarction of spleen	0.000	0.992	0.008
D12.4 Descending colon	0.008	0.992	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.992	0.008
D74.8 Other methaemoglobinaemias	0.000	0.992	0.008
D74.0 Congenital methaemoglobinaemia	0.000	0.992	0.008
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
E06.9 Thyroiditis, unspecified	0.006	0.992	0.002
C71 Malignant neoplasm of brain	0.008	0.992	0.000
J98.4 Other disorders of lung	0.008	0.992	0.000
K91.1 Postgastric surgery syndromes	0.000	0.992	0.008
D72.1 Eosinophilia	0.000	0.992	0.007
C18.4 Transverse colon	0.007	0.992	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.993	0.007
C71.2 Temporal lobe	0.007	0.993	0.000
E04 Other non-toxic goitre	0.007	0.993	0.001
R94.3 Abnormal results of cardiovascular function studies	0.007	0.993	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.993	0.003
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.993	0.007
F43.1 Posttraumatic stress disorder	0.007	0.993	0.000
D86 Sarcoidosis	0.000	0.993	0.007
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
E66 Obesity	0.000	0.993	0.007
D86.9 Sarcoidosis, unspecified	0.000	0.994	0.006
D12.9 Anus and anal canal	0.006	0.994	0.000
E66.0 Obesity due to excess calories	0.000	0.994	0.006
S64 Injury of nerves at wrist and hand level	0.006	0.994	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
F43 Reaction to severe stress, and adjustment disorders	0.006	0.994	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
F43.0 Acute stress reaction	0.006	0.994	0.000
C71.4 Occipital lobe	0.006	0.994	0.000
C71.7 Brain stem	0.006	0.994	0.000
C71.6 Cerebellum	0.006	0.994	0.000
C71.5 Cerebral ventricle	0.006	0.994	0.000
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.994	0.005
E04.8 Other specified non-toxic goitre	0.005	0.995	0.001
M20-M25 Other joint disorders	0.000	0.995	0.005
D86.1 Sarcoidosis of lymph nodes	0.000	0.995	0.005
E05.8 Other thyrotoxicosis	0.003	0.995	0.002
E05.5 Thyroid crisis or storm	0.003	0.995	0.002
E05.4 Thyrotoxicosis factitia	0.003	0.995	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.995	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.995	0.002
M21 Other acquired deformities of limbs	0.000	0.995	0.005
D12.1 Appendix	0.005	0.995	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.995	0.005
D12.2 Ascending colon	0.005	0.995	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.005	0.995	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.995	0.005
E11.4 With neurological complications	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.000	0.995	0.005
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.995	0.005
D80-D89 Certain disorders involving the immune mechanism	0.000	0.995	0.005
C71.8 Overlapping lesion of brain	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
E66.1 Drug-induced obesity	0.000	0.995	0.005
M24 Other specific joint derangements	0.000	0.995	0.005
E04.0 Non-toxic diffuse goitre	0.004	0.995	0.001
I27.0 Primary pulmonary hypertension	0.000	0.995	0.005
S64.2 Injury of radial nerve at wrist and hand level	0.005	0.995	0.000
K92.8 Other specified diseases of digestive system	0.000	0.995	0.005
M21.3 Wrist or foot drop (acquired)	0.000	0.995	0.005
S64.0 Injury of ulnar nerve at wrist and hand level	0.005	0.995	0.000
I42.8 Other cardiomyopathies	0.005	0.995	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.995	0.004
M24.0 Loose body in joint	0.000	0.995	0.005
C71.1 Frontal lobe	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.000	0.995	0.005
S64.1 Injury of median nerve at wrist and hand level	0.005	0.995	0.000
C44.4 Skin of scalp and neck	0.005	0.995	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.995	0.002
I27 Other pulmonary heart diseases	0.000	0.995	0.005
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.995	0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.995	0.005
S64.9 Injury of unspecified nerve at wrist and hand level	0.005	0.995	0.000
S64.8 Injury of other nerves at wrist and hand level	0.005	0.995	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.995	0.005
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.995	0.005
F43.9 Reaction to severe stress, unspecified	0.005	0.995	0.000
K92 Other diseases of digestive system	0.000	0.995	0.005
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.995	0.005
I27.9 Pulmonary heart disease, unspecified	0.000	0.995	0.005
F43.8 Other reactions to severe stress	0.004	0.995	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.995	0.005
M31 Other necrotising vasculopathies	0.000	0.995	0.005
F43.2 Adjustment disorders	0.004	0.995	0.000
R63.0 Anorexia	0.000	0.996	0.004
M24.01 Loose body in joint (Shoulder region)	0.000	0.996	0.004
M32 Systemic lupus erythematosus	0.000	0.996	0.004
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
F41.2 Mixed anxiety and depressive disorder	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.996	0.004
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.996	0.004
M30 Polyarteritis nodosa and related conditions	0.000	0.996	0.004
M34 Systemic sclerosis	0.000	0.996	0.004
D12.6 Colon, unspecified	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.996	0.004
M21.4 Flat foot [pes planus] (acquired)	0.000	0.996	0.004
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.004	0.996	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.996	0.004
M21.6 Other acquired deformities of ankle and foot	0.000	0.996	0.004
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.996	0.004
M21.9 Acquired deformity of limb, unspecified	0.000	0.996	0.004
M21.8 Other specified acquired deformities of limbs	0.000	0.996	0.004
M21.7 Unequal limb length (acquired)	0.000	0.996	0.004
M31.6 Other giant cell arteritis	0.000	0.996	0.004
I42 Cardiomyopathy	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.996	0.004
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.996	0.004
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.996	0.004
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.996	0.004
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.996	0.004
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.996	0.004
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.996	0.004
M07.3 Other psoriatic arthropathies	0.000	0.996	0.004
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.996	0.004
E04.1 Non-toxic single thyroid nodule	0.004	0.996	0.000
I42.6 Alcoholic cardiomyopathy	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
E65 Localised adiposity	0.000	0.996	0.004
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.996	0.004
D81 Combined immunodeficiencies	0.000	0.996	0.004
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.996	0.004
E11 Non-insulin-dependent diabetes mellitus	0.000	0.996	0.004
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.996	0.004
M24.6 Ankylosis of joint	0.000	0.996	0.004
M24.9 Joint derangement, unspecified	0.000	0.996	0.004
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.996	0.004
M33 Dermatopolymyositis	0.000	0.996	0.004
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.996	0.004
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.996	0.004
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.996	0.004
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.996	0.004
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.996	0.004
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.996	0.004
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.996	0.004
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.996	0.004
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.996	0.004
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.996	0.004
M24.09 Loose body in joint (Site unspecified)	0.000	0.996	0.004
M24.08 Loose body in joint (Other)	0.000	0.996	0.004
M24.06 Loose body in joint-Lower leg	0.000	0.996	0.004
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.996	0.004
M24.04 Loose body in joint (Hand)	0.000	0.996	0.004
M24.03 Loose body in joint (Forearm)	0.000	0.996	0.004
M24.00 Loose body in joint (Multiple sites)	0.000	0.996	0.004
E11.2 With renal complications	0.000	0.996	0.004
D50-D53 Nutritional anaemias	0.000	0.996	0.004
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.996	0.004
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.996	0.004
M24.18 Other articular cartilage disorders (Other)	0.000	0.996	0.004
M24.14 Other articular cartilage disorders (Hand)	0.000	0.996	0.004
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.996	0.004
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.996	0.004
D83 Common variable immunodeficiency	0.000	0.996	0.004
J98 Other respiratory disorders	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.996	0.004
C44.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.996	0.004
I46.0 Cardiac arrest with successful resuscitation	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
M24.2 Disorder of ligament	0.000	0.996	0.004
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
I42.4 Endocardial fibroelastosis	0.004	0.996	0.000
S60.8 Other superficial injuries of wrist and hand	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.996	0.003
M34.9 Systemic sclerosis, unspecified	0.000	0.996	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.996	0.003
D41.2 Ureter	0.003	0.996	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.996	0.003
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.996	0.003
M31.2 Lethal midline granuloma	0.000	0.996	0.003
M31.1 Thrombotic microangiopathy	0.000	0.996	0.003
M31.0 Hypersensitivity angiitis	0.000	0.996	0.003
D84 Other immunodeficiencies	0.000	0.996	0.003
J98.8 Other specified respiratory disorders	0.003	0.996	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.004	0.996	0.000
C44.0 Skin of lip	0.003	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.997	0.003
I26 Pulmonary embolism	0.000	0.997	0.003
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.997	0.003
M32.8 Other forms of systemic lupus erythematosus	0.000	0.997	0.003
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.997	0.003
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.000	0.997	0.003
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.997	0.003
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.997	0.003
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.997	0.003
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.997	0.003
M24.7 Protrusio acetabuli	0.000	0.997	0.003
F41 Other anxiety disorders	0.003	0.997	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.997	0.003
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.997	0.003
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.997	0.003
M30.2 Juvenile polyarteritis	0.000	0.997	0.003
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
M31.3 Wegener's granulomatosis	0.000	0.997	0.003
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.997	0.003
M34.0 Progressive systemic sclerosis	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.997	0.003
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.997	0.003
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.003
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.997	0.003
E11.8 With unspecified complications	0.000	0.997	0.003
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
C61 Malignant neoplasm of prostate	0.000	0.997	0.003
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.997	0.003
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.997	0.003
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.997	0.003
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.997	0.003
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.997	0.003
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.997	0.003
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.997	0.003
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.997	0.003
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.997	0.003
D53 Other nutritional anaemias	0.000	0.997	0.003
D41.9 Urinary organ, unspecified	0.003	0.997	0.000
D41.7 Other urinary organs	0.003	0.997	0.000
D41.3 Urethra	0.003	0.997	0.000
D41.1 Renal pelvis	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.997	0.003
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.997	0.003
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.997	0.003
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.997	0.003
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.997	0.003
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.997	0.003
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.997	0.003
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations