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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2524168
log Bayes Factor = 28.618
Chromosome 6   position 31,275,163  (GRCh37) Explore rs2524168 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.000 0.054 0.946
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.314 0.686
E03 Other hypothyroidism
0.596 0.317 0.087
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.453 0.547
L40.8 Other psoriasis
0.000 0.455 0.544
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.500 0.456 0.044
E05 Thyrotoxicosis [hyperthyroidism]
0.001 0.462 0.537
E05.9 Thyrotoxicosis, unspecified
0.000 0.498 0.502
E03.5 Myxoedema coma
0.427 0.510 0.062
E03.4 Atrophy of thyroid (acquired)
0.427 0.510 0.062
E03.3 Postinfectious hypothyroidism
0.427 0.510 0.062
E03.1 Congenital hypothyroidism without goitre
0.427 0.510 0.062
E03.0 Congenital hypothyroidism with diffuse goitre
0.427 0.510 0.062
E00-E07 Disorders of thyroid gland
0.024 0.511 0.465
E03.8 Other specified hypothyroidism
0.406 0.538 0.056
E05.8 Other thyrotoxicosis
0.001 0.557 0.443
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.557 0.443
E10 Insulin-dependent diabetes mellitus
0.000 0.565 0.435
E10-E14 Diabetes mellitus
0.000 0.568 0.432
E50-E64 Other nutritional deficiencies
0.000 0.573 0.427
E06 Thyroiditis
0.009 0.580 0.411
E10.3 With ophthalmic complications
0.000 0.586 0.414
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.592 0.407
E65-E68 Obesity and other hyperalimentation
0.000 0.594 0.406
E10.1 With ketoacidosis
0.000 0.602 0.398
E10.2 With renal complications
0.000 0.602 0.398
E55 Vitamin D deficiency
0.000 0.608 0.392
E53 Deficiency of other B group vitamins
0.000 0.611 0.389
E05.5 Thyroid crisis or storm
0.001 0.614 0.385
E05.4 Thyrotoxicosis factitia
0.001 0.614 0.385
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.001 0.614 0.385
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.001 0.614 0.385
E06.9 Thyroiditis, unspecified
0.004 0.632 0.365
E55.9 Vitamin D deficiency, unspecified
0.000 0.632 0.368
E66 Obesity
0.000 0.632 0.368
E10.8 With unspecified complications
0.000 0.649 0.351
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.018 0.649 0.333
E00 Congenital iodine-deficiency syndrome
0.018 0.649 0.333
E53.8 Deficiency of other specified B group vitamins
0.000 0.653 0.347
E02 Subclinical iodine-deficiency hypothyroidism
0.018 0.662 0.320
E40-E46 Malnutrition
0.000 0.666 0.334
E66.8 Other obesity
0.000 0.666 0.334
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.670 0.330
E65 Localised adiposity
0.000 0.672 0.328
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.677 0.323
E10.4 With neurological complications
0.000 0.677 0.323
E53.9 Vitamin B deficiency, unspecified
0.000 0.681 0.319
E10.9 Without complications
0.000 0.681 0.319
E06.3 Autoimmune thyroiditis
0.003 0.681 0.315
E10.5 With peripheral circulatory complications
0.000 0.682 0.318
L40-L45 Papulosquamous disorders
0.000 0.684 0.316
K90 Intestinal malabsorption
0.000 0.687 0.313
E10.7 With multiple complications
0.000 0.688 0.312
E12 Malnutrition-related diabetes mellitus
0.000 0.690 0.310
E61 Deficiency of other nutrient elements
0.000 0.692 0.307
E51 Thiamine deficiency
0.000 0.693 0.307
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.694 0.306
E63 Other nutritional deficiencies
0.000 0.694 0.306
E50 Vitamin A deficiency
0.000 0.694 0.306
E60 Dietary zinc deficiency
0.000 0.694 0.306
E59 Dietary selenium deficiency
0.000 0.694 0.306
E58 Dietary calcium deficiency
0.000 0.694 0.306
E54 Ascorbic acid deficiency
0.000 0.694 0.306
E52 Niacin deficiency [pellagra]
0.000 0.694 0.306
E66.0 Obesity due to excess calories
0.000 0.697 0.303
E06.5 Other chronic thyroiditis
0.006 0.699 0.295
E06.4 Drug-induced thyroiditis
0.006 0.699 0.295
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.006 0.699 0.295
E06.1 Subacute thyroiditis
0.006 0.699 0.295
E06.0 Acute thyroiditis
0.006 0.699 0.295
E10.6 With other specified complications
0.000 0.700 0.300
E67 Other hyperalimentation
0.000 0.709 0.291
E68 Sequelae of hyperalimentation
0.000 0.709 0.291
E56 Other vitamin deficiencies
0.000 0.711 0.289
E55.0 Rickets, active
0.000 0.719 0.281
E53.1 Pyridoxine deficiency
0.000 0.721 0.279
E53.0 Riboflavin deficiency
0.000 0.721 0.279
E10.0 With coma
0.000 0.736 0.264
E66.1 Drug-induced obesity
0.000 0.736 0.264
E46 Unspecified protein-energy malnutrition
0.000 0.744 0.255
E04 Other non-toxic goitre
0.002 0.746 0.252
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.013 0.748 0.239
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.013 0.748 0.239
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.013 0.748 0.239
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.013 0.748 0.239
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.013 0.748 0.239
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.013 0.748 0.239
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.013 0.748 0.239
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.013 0.748 0.239
E13 Other specified diabetes mellitus
0.000 0.750 0.250
E14 Unspecified diabetes mellitus
0.000 0.752 0.248
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.760 0.239
E45 Retarded development following protein-energy malnutrition
0.000 0.760 0.239
E43 Unspecified severe protein-energy malnutrition
0.000 0.760 0.239
E42 Marasmic kwashiorkor
0.000 0.760 0.239
E41 Nutritional marasmus
0.000 0.760 0.239
E40 Kwashiorkor
0.000 0.760 0.239
E16 Other disorders of pancreatic internal secretion
0.000 0.763 0.237
E15 Nondiabetic hypoglycaemic coma
0.000 0.768 0.232
E11 Non-insulin-dependent diabetes mellitus
0.000 0.769 0.231
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.769 0.231
E61.2 Magnesium deficiency
0.000 0.769 0.231
L44 Other papulosquamous disorders
0.000 0.773 0.226
L41 Parapsoriasis
0.000 0.773 0.226
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.773 0.226
K90.3 Pancreatic steatorrhoea
0.000 0.775 0.225
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.775 0.225
K90.1 Tropical sprue
0.000 0.775 0.225
E12.9 Without complications
0.000 0.778 0.222
E12.8 With unspecified complications
0.000 0.778 0.222
E12.7 With multiple complications
0.000 0.778 0.222
E12.6 With other specified complications
0.000 0.778 0.222
E12.5 With peripheral circulatory complications
0.000 0.778 0.222
E12.4 With neurological complications
0.000 0.778 0.222
E12.3 With ophthalmic complications
0.000 0.778 0.222
E12.2 With renal complications
0.000 0.778 0.222
E12.1 With ketoacidosis
0.000 0.778 0.222
E12.0 With coma
0.000 0.778 0.222
E51.2 Wernicke's encephalopathy
0.000 0.778 0.221
E61.9 Deficiency of nutrient element, unspecified
0.000 0.779 0.221
E61.8 Deficiency of other specified nutrient elements
0.000 0.779 0.221
E61.7 Deficiency of multiple nutrient elements
0.000 0.779 0.221
E61.6 Vanadium deficiency
0.000 0.779 0.221
E61.5 Molybdenum deficiency
0.000 0.779 0.221
E61.4 Chromium deficiency
0.000 0.779 0.221
E61.3 Manganese deficiency
0.000 0.779 0.221
E61.0 Copper deficiency
0.000 0.779 0.221
E51.9 Thiamine deficiency, unspecified
0.000 0.780 0.220
E51.8 Other manifestations of thiamine deficiency
0.000 0.780 0.220
E51.1 Beriberi
0.000 0.780 0.220
E50.9 Vitamin A deficiency, unspecified
0.000 0.780 0.219
E50.8 Other manifestations of vitamin A deficiency
0.000 0.780 0.219
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.780 0.219
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.780 0.219
E50.5 Vitamin A deficiency with night blindness
0.000 0.780 0.219
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.780 0.219
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.780 0.219
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.780 0.219
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.780 0.219
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.780 0.219
E63.9 Nutritional deficiency, unspecified
0.000 0.780 0.219
E63.8 Other specified nutritional deficiencies
0.000 0.780 0.219
E63.1 Imbalance of constituents of food intake
0.000 0.780 0.219
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.780 0.219
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.780 0.219
E64.8 Sequelae of other nutritional deficiencies
0.000 0.780 0.219
E64.3 Sequelae of rickets
0.000 0.780 0.219
E64.2 Sequelae of vitamin C deficiency
0.000 0.780 0.219
E64.1 Sequelae of vitamin A deficiency
0.000 0.780 0.219
E64.0 Sequelae of protein-energy malnutrition
0.000 0.780 0.219
L42 Pityriasis rosea
0.000 0.784 0.216
E61.1 Iron deficiency
0.000 0.790 0.210
E67.8 Other specified hyperalimentation
0.000 0.791 0.209
E67.3 Hypervitaminosis D
0.000 0.791 0.209
E67.2 Megavitamin-B6 syndrome
0.000 0.791 0.209
E67.1 Hypercarotenaemia
0.000 0.791 0.209
E67.0 Hypervitaminosis A
0.000 0.791 0.209
E14.3 With ophthalmic complications
0.000 0.792 0.208
E56.9 Vitamin deficiency, unspecified
0.000 0.793 0.207
E56.8 Deficiency of other vitamins
0.000 0.793 0.207
E56.0 Deficiency of vitamin E
0.000 0.793 0.207
K90.9 Intestinal malabsorption, unspecified
0.000 0.804 0.196
E14.8 With unspecified complications
0.000 0.805 0.194
E16.2 Hypoglycaemia, unspecified
0.000 0.806 0.194
E04.0 Non-toxic diffuse goitre
0.001 0.807 0.191
K90.8 Other intestinal malabsorption
0.000 0.809 0.190
L43 Lichen planus
0.000 0.809 0.190
E56.1 Deficiency of vitamin K
0.000 0.810 0.190
E07 Other disorders of thyroid
0.022 0.810 0.168
E14.1 With ketoacidosis
0.000 0.814 0.186
E11.4 With neurological complications
0.000 0.817 0.183
E04.8 Other specified non-toxic goitre
0.002 0.818 0.180
E13.8 With unspecified complications
0.000 0.820 0.179
E13.7 With multiple complications
0.000 0.820 0.179
E13.6 With other specified complications
0.000 0.820 0.179
E13.5 With peripheral circulatory complications
0.000 0.820 0.179
E13.4 With neurological complications
0.000 0.820 0.179
E13.3 With ophthalmic complications
0.000 0.820 0.179
E13.2 With renal complications
0.000 0.820 0.179
E13.1 With ketoacidosis
0.000 0.820 0.179
E13.0 With coma
0.000 0.820 0.179
E14.7 With multiple complications
0.000 0.822 0.178
E14.2 Withrenal complications
0.000 0.822 0.178
E14.0 With coma
0.000 0.822 0.178
E11.3 With ophthalmic complications
0.000 0.826 0.174
E04.1 Non-toxic single thyroid nodule
0.001 0.826 0.173
E44.1 Mild protein-energy malnutrition
0.000 0.828 0.172
E44.0 Moderate protein-energy malnutrition
0.000 0.828 0.172
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.830 0.170
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.830 0.170
E16.4 Abnormal secretion of gastrin
0.000 0.830 0.170
E16.3 Increased secretion of glucagon
0.000 0.830 0.170
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.830 0.170
E14.5 With peripheral circulatory complications
0.000 0.830 0.170
E11.1 With ketoacidosis
0.000 0.833 0.167
E11.7 With multiple complications
0.000 0.834 0.166
E14.6 With other specified complications
0.000 0.834 0.166
E11.8 With unspecified complications
0.000 0.837 0.163
L41.9 Parapsoriasis, unspecified
0.000 0.837 0.162
L41.8 Other parapsoriasis
0.000 0.837 0.162
L41.5 Retiform parapsoriasis
0.000 0.837 0.162
L41.4 Large plaque parapsoriasis
0.000 0.837 0.162
L41.3 Small plaque parapsoriasis
0.000 0.837 0.162
L41.2 Lymphomatoid papulosis
0.000 0.837 0.162
L41.1 Pityriasis lichenoides chronica
0.000 0.837 0.162
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.837 0.162
L44.9 Papulosquamous disorder, unspecified
0.000 0.837 0.162
L44.8 Other specified papulosquamous disorders
0.000 0.837 0.162
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.837 0.162
L44.3 Lichen ruber moniliformis
0.000 0.837 0.162
L44.2 Lichen striatus
0.000 0.837 0.162
L44.1 Lichen nitidus
0.000 0.837 0.162
L44.0 Pityriasis rubra pilaris
0.000 0.837 0.162
E11.0 With coma
0.000 0.838 0.162
E11.6 With other specified complications
0.000 0.839 0.161
E14.4 With neurological complications
0.000 0.841 0.159
E11.5 With peripheral circulatory complications
0.000 0.842 0.158
E11.2 With renal complications
0.000 0.848 0.152
E04.2 Non-toxic multinodular goitre
0.000 0.854 0.146
E16.1 Other hypoglycaemia
0.000 0.858 0.142
E04.9 Non-toxic goitre, unspecified
0.001 0.859 0.141
L43.8 Other lichen planus
0.000 0.861 0.139
L43.3 Subacute (active) lichen planus
0.000 0.863 0.137
L43.2 Lichenoid drug reaction
0.000 0.863 0.137
L43.1 Bullous lichen planus
0.000 0.863 0.137
L43.0 Hypertrophic lichen planus
0.000 0.863 0.137
E07.1 Dyshormogenetic goitre
0.016 0.864 0.120
E07.0 Hypersecretion of calcitonin
0.016 0.864 0.120
E13.9 Without complications
0.000 0.880 0.119
E07.8 Other specified disorders of thyroid
0.018 0.889 0.094
L43.9 Lichen planus, unspecified
0.000 0.904 0.096
E11.9 Without complications
0.000 0.905 0.095
G35 Multiple sclerosis
0.000 0.944 0.056
E07.9 Disorder of thyroid, unspecified
0.020 0.949 0.031
E14.9 Without complications
0.000 0.954 0.046
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.957 0.043
G37 Other demyelinating diseases of central nervous system
0.000 0.959 0.041
E20-E35 Disorders of other endocrine glands
0.000 0.962 0.038
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.964 0.036
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.964 0.036
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.966 0.034
D70 Agranulocytosis
0.000 0.966 0.034
D75 Other diseases of blood and blood-forming organs
0.000 0.967 0.033
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.968 0.032
D72 Other disorders of white blood cells
0.000 0.968 0.032
D72.8 Other specified disorders of white blood cells
0.000 0.969 0.031
G36 Other acute disseminated demyelination
0.000 0.970 0.030
G37.5 Concentric sclerosis [Balo]
0.000 0.970 0.029
G37.4 Subacute necrotising myelitis
0.000 0.970 0.029
G37.2 Central pontine myelinolysis
0.000 0.970 0.029
G37.1 Central demyelination of corpus callosum
0.000 0.970 0.029
G37.0 Diffuse sclerosis
0.000 0.970 0.029
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.971 0.029
E26 Hyperaldosteronism
0.000 0.971 0.028
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.972 0.028
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.972 0.027
E32 Diseases of thymus
0.000 0.972 0.027
E31 Polyglandular dysfunction
0.000 0.972 0.027
E30 Disorders of puberty, not elsewhere classified
0.000 0.972 0.027
E27 Other disorders of adrenal gland
0.000 0.972 0.028
D75.2 Essential thrombocytosis
0.000 0.973 0.027
E25 Adrenogenital disorders
0.000 0.973 0.026
E20 Hypoparathyroidism
0.000 0.973 0.026
D73 Diseases of spleen
0.000 0.974 0.026
E34 Other endocrine disorders
0.000 0.974 0.026
E24 Cushing's syndrome
0.000 0.974 0.025
D75.1 Secondary polycythaemia
0.000 0.975 0.025
E22 Hyperfunction of pituitary gland
0.000 0.975 0.025
D74 Methaemoglobinaemia
0.000 0.975 0.025
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.975 0.025
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.975 0.025
E27.1 Primary adrenocortical insufficiency
0.000 0.975 0.025
E29 Testicular dysfunction
0.000 0.976 0.024
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.976 0.024
D75.0 Familial erythrocytosis
0.000 0.976 0.024
K90-K93 Other diseases of the digestive system
0.000 0.976 0.024
D72.9 Disorder of white blood cells, unspecified
0.000 0.977 0.023
D72.0 Genetic anomalies of leukocytes
0.000 0.977 0.023
D72.1 Eosinophilia
0.000 0.977 0.023
D86 Sarcoidosis
0.000 0.977 0.023
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.978 0.022
E27.8 Other specified disorders of adrenal gland
0.000 0.978 0.022
G36.9 Acute disseminated demyelination, unspecified
0.000 0.978 0.022
G36.8 Other specified acute disseminated demyelination
0.000 0.978 0.022
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.978 0.022
D86.9 Sarcoidosis, unspecified
0.000 0.978 0.022
E26.0 Primary hyperaldosteronism
0.000 0.978 0.022
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.978 0.022
D73.0 Hyposplenism
0.000 0.978 0.022
E34.0 Carcinoid syndrome
0.000 0.978 0.021
G36.0 Neuromyelitis optica [Devic]
0.000 0.979 0.021
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.979 0.021
M25.5 Pain in joint
0.000 0.979 0.021
E26.9 Hyperaldosteronism, unspecified
0.000 0.979 0.021
E26.8 Other hyperaldosteronism
0.000 0.979 0.021
E26.1 Secondary hyperaldosteronism
0.000 0.979 0.021
M07.3 Other psoriatic arthropathies
0.000 0.979 0.021
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.980 0.020
M25.54 Pain in joint (Hand)
0.000 0.980 0.020
S64.4 Injury of digital nerve of other finger
0.020 0.980 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.980 0.020
E30.9 Disorder of puberty, unspecified
0.000 0.980 0.020
E30.8 Other disorders of puberty
0.000 0.980 0.020
E30.1 Precocious puberty
0.000 0.980 0.020
E30.0 Delayed puberty
0.000 0.980 0.020
E31.9 Polyglandular dysfunction, unspecified
0.000 0.980 0.020
E31.8 Other polyglandular dysfunction
0.000 0.980 0.020
E31.1 Polyglandular hyperfunction
0.000 0.980 0.020
E31.0 Autoimmune polyglandular failure
0.000 0.980 0.020
E32.9 Disease of thymus, unspecified
0.000 0.980 0.020
E32.8 Other diseases of thymus
0.000 0.980 0.020
E32.1 Abscess of thymus
0.000 0.980 0.020
E32.0 Persistent hyperplasia of thymus
0.000 0.980 0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.980 0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.980 0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.980 0.020
E27.5 Adrenomedullary hyperfunction
0.000 0.980 0.020
E27.0 Other adrenocortical overactivity
0.000 0.980 0.020
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.980 0.020
D86.0 Sarcoidosis of lung
0.000 0.980 0.020
D73.1 Hypersplenism
0.000 0.980 0.020
D86.8 Sarcoidosis of other and combined sites
0.000 0.980 0.020
D73.8 Other diseases of spleen
0.000 0.981 0.019
E25.9 Adrenogenital disorder, unspecified
0.000 0.981 0.019
E25.8 Other adrenogenital disorders
0.000 0.981 0.019
E24.0 Pituitary-dependent Cushing's disease
0.000 0.981 0.019
E20.8 Other hypoparathyroidism
0.000 0.981 0.019
E20.1 Pseudohypoparathyroidism
0.000 0.981 0.019
E20.0 Idiopathic hypoparathyroidism
0.000 0.981 0.019
M25.59 Pain in joint (Site unspecified)
0.000 0.981 0.019
D73.9 Disease of spleen, unspecified
0.000 0.981 0.019
D73.3 Abscess of spleen
0.000 0.981 0.019
D73.2 Chronic congestive splenomegaly
0.000 0.981 0.019
E34.5 Androgen resistance syndrome
0.000 0.981 0.018
E34.4 Constitutional tall stature
0.000 0.981 0.018
E34.3 Short stature, not elsewhere classified
0.000 0.981 0.018
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.981 0.018
E34.1 Other hypersecretion of intestinal hormones
0.000 0.981 0.018
M25.50 Pain in joint (Multiple sites)
0.000 0.981 0.019
E22.0 Acromegaly and pituitary gigantism
0.000 0.981 0.019
E24.8 Other Cushing's syndrome
0.000 0.981 0.018
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.981 0.018
E24.3 Ectopic ACTH syndrome
0.000 0.981 0.018
E24.1 Nelson's syndrome
0.000 0.981 0.018
E22.1 Hyperprolactinaemia
0.000 0.981 0.018
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.982 0.018
E27.2 Addisonian crisis
0.000 0.982 0.018
E20.9 Hypoparathyroidism, unspecified
0.000 0.982 0.018
D73.5 Infarction of spleen
0.000 0.982 0.018
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.982 0.018
E22.8 Other hyperfunction of pituitary gland
0.000 0.982 0.018
D74.9 Methaemoglobinaemia, unspecified
0.000 0.982 0.018
D74.8 Other methaemoglobinaemias
0.000 0.982 0.018
D74.0 Congenital methaemoglobinaemia
0.000 0.982 0.018
E24.2 Drug-induced Cushing's syndrome
0.000 0.982 0.017
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.982 0.017
E29.9 Testicular dysfunction, unspecified
0.000 0.982 0.017
E29.8 Other testicular dysfunction
0.000 0.982 0.017
E29.0 Testicular hyperfunction
0.000 0.982 0.017
M25.51 Pain in joint (Shoulder region)
0.000 0.982 0.018
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.982 0.017
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.982 0.017
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.982 0.017
D80-D89 Certain disorders involving the immune mechanism
0.000 0.983 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.983 0.017
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.983 0.017
D76.3 Other histiocytosis syndromes
0.000 0.983 0.017
D86.3 Sarcoidosis of skin
0.000 0.983 0.016
E24.9 Cushing's syndrome, unspecified
0.000 0.983 0.016
E27.9 Disorder of adrenal gland, unspecified
0.000 0.984 0.016
I26 Pulmonary embolism
0.000 0.984 0.016
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.984 0.016
E34.9 Endocrine disorder, unspecified
0.000 0.984 0.015
E34.8 Other specified endocrine disorders
0.000 0.984 0.015
D73.4 Cyst of spleen
0.000 0.984 0.016
E28 Ovarian dysfunction
0.002 0.985 0.014
M25.52 Pain in joint (Upper arm)
0.000 0.985 0.015
M25.58 Pain in joint (Other)
0.000 0.985 0.015
I27.9 Pulmonary heart disease, unspecified
0.000 0.985 0.015
M07.38 Other psoriatic arthropathies (Other)
0.000 0.985 0.015
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.985 0.015
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.985 0.015
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.985 0.015
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.985 0.015
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.985 0.015
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.985 0.015
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.985 0.015
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.985 0.015
I27 Other pulmonary heart diseases
0.000 0.985 0.015
I27.0 Primary pulmonary hypertension
0.000 0.986 0.014
E29.1 Testicular hypofunction
0.000 0.986 0.014
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.986 0.014
E21.0 Primary hyperparathyroidism
0.000 0.987 0.013
M25.53 Pain in joint (Forearm)
0.000 0.987 0.013
M25.57 Pain in joint (Ankle and foot)
0.000 0.987 0.013
E21.4 Other specified disorders of parathyroid gland
0.000 0.987 0.013
E21.2 Other hyperparathyroidism
0.000 0.987 0.013
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.987 0.013
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.987 0.013
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.987 0.013
D82 Immunodeficiency associated with other major defects
0.000 0.987 0.013
D81 Combined immunodeficiencies
0.000 0.987 0.013
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.987 0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.987 0.012
K93.1 Megacolon in Chagas' disease
0.000 0.987 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.987 0.012
D83 Common variable immunodeficiency
0.000 0.988 0.012
S64 Injury of nerves at wrist and hand level
0.012 0.988 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.988 0.012
E28.9 Ovarian dysfunction, unspecified
0.001 0.989 0.010
E28.8 Other ovarian dysfunction
0.001 0.989 0.010
E28.1 Androgen excess
0.001 0.989 0.010
E28.0 Oestrogen excess
0.001 0.989 0.010
J98.4 Other disorders of lung
0.011 0.989 0.000
E23 Hypofunction and other disorders of pituitary gland
0.001 0.989 0.011
D84 Other immunodeficiencies
0.000 0.989 0.011
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.989 0.011
I27.1 Kyphoscoliotic heart disease
0.000 0.989 0.011
D55-D59 Haemolytic anaemias
0.000 0.989 0.011
D66 Hereditary factor VIII deficiency
0.000 0.989 0.011
S64.0 Injury of ulnar nerve at wrist and hand level
0.011 0.989 0.000
I28 Other diseases of pulmonary vessels
0.000 0.989 0.010
S64.7 Injury of multiple nerves at wrist and hand level
0.010 0.990 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.010 0.990 0.000
D89.1 Cryoglobulinaemia
0.000 0.990 0.010
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.990 0.009
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.990 0.009
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.991 0.009
D89.3 Immune reconstitution syndrome
0.000 0.991 0.009
D81.9 Combined immunodeficiency, unspecified
0.000 0.991 0.009
D81.8 Other combined immunodeficiencies
0.000 0.991 0.009
D81.7 Major histocompatibility complex class II deficiency
0.000 0.991 0.009
D81.6 Major histocompatibility complex class I deficiency
0.000 0.991 0.009
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.991 0.009
D81.4 Nezelof's syndrome
0.000 0.991 0.009
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.991 0.009
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.991 0.009
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.991 0.009
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.991 0.009
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.991 0.009
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.991 0.009
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.991 0.009
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.991 0.009
D82.2 Immunodeficiency with short-limbed stature
0.000 0.991 0.009
D82.1 Di George's syndrome
0.000 0.991 0.009
D82.0 Wiskott-Aldrich syndrome
0.000 0.991 0.009
E28.3 Primary ovarian failure
0.001 0.991 0.008
D67 Hereditary factor IX deficiency
0.000 0.991 0.009
D68 Other coagulation defects
0.000 0.991 0.009
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.991 0.009
D83.8 Other common variable immunodeficiencies
0.000 0.991 0.009
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.991 0.009
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.991 0.009
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.991 0.009
I27.8 Other specified pulmonary heart diseases
0.000 0.991 0.009
C71.9 Brain, unspecified
0.009 0.991 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.009 0.991 0.000
S64.8 Injury of other nerves at wrist and hand level
0.009 0.991 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.991 0.009
I28.8 Other specified diseases of pulmonary vessels
0.000 0.991 0.009
M07 Psoriatic and enteropathic arthropathies
0.000 0.991 0.009
I84.9 Unspecified haemorrhoids without complication
0.009 0.991 0.000
D83.9 Common variable immunodeficiency, unspecified
0.000 0.991 0.008
S64.2 Injury of radial nerve at wrist and hand level
0.008 0.991 0.000
M25 Other joint disorders, not elsewhere classified
0.000 0.991 0.009
I27.2 Other secondary pulmonary hypertension
0.000 0.992 0.008
D50-D53 Nutritional anaemias
0.000 0.992 0.008
D69 Purpura and other haemorrhagic conditions
0.000 0.992 0.008
M25.9 Joint disorder, unspecified
0.000 0.992 0.008
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.992 0.008
E23.1 Drug-induced hypopituitarism
0.001 0.992 0.008
D84.8 Other specified immunodeficiencies
0.000 0.992 0.008
D84.1 Defects in the complement system
0.000 0.992 0.008
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.992 0.008
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.992 0.008
E23.7 Disorder of pituitary gland, unspecified
0.000 0.992 0.008
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.000 0.992 0.008
D57 Sickle-cell disorders
0.000 0.992 0.008
D55 Anaemia due to enzyme disorders
0.000 0.992 0.008
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.992 0.008
C71 Malignant neoplasm of brain
0.008 0.992 0.000
S64.1 Injury of median nerve at wrist and hand level
0.008 0.992 0.000
I28.1 Aneurysm of pulmonary artery
0.000 0.992 0.008
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.992 0.008
D59 Acquired haemolytic anaemia
0.000 0.992 0.008
D80 Immunodeficiency with predominantly antibody defects
0.000 0.992 0.007
D58 Other hereditary haemolytic anaemias
0.000 0.992 0.007
C71.0 Cerebrum, except lobes and ventricles
0.008 0.992 0.000
D68.6 Other Thrombophilia
0.000 0.992 0.007
D56 Thalassaemia
0.000 0.993 0.007
D68.9 Coagulation defect, unspecified
0.000 0.993 0.007
D68.8 Other specified coagulation defects
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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