TreeWAS – Variant ID: rs2526391

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
M20-M25 Other joint disorders	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.998	0.002
M50-M54 Other dorsopathies	0.979	0.021
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.978	0.022
M20 Acquired deformities of fingers and toes	0.978	0.022
M45-M49 Spondylopathies	0.976	0.024
M50 Cervical disk disorders	0.972	0.028
M24 Other specific joint derangements	0.969	0.031
S50-S59 Injuries to the elbow and forearm	0.967	0.033
M50.0 Cervical disk disorder with myelopathy	0.957	0.043
O80-O84 Delivery	0.957	0.043
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.955	0.045
M20.2 Hallux rigidus	0.950	0.050
T36-T50 Poisoning by drugs, medicaments and biological substances	0.931	0.069
O80 Single spontaneous delivery	0.923	0.077
Chapter XII Diseases of the skin and subcutaneous tissue	0.922	0.078
M47 Spondylosis	0.921	0.079
M22 Disorders of patella	0.920	0.080
O36 Maternal care for other known or suspected foetal problems	0.919	0.081
Z40-Z54 Persons encountering health services for specific procedures and health care	0.917	0.083
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.917	0.083
Chapter XXI Factors influencing health status and contact with health services	0.912	0.088
Z45 Adjustment and management of implanted device	0.910	0.090
T20-T25 Burns and corrosions of external body surface, specified by site	0.908	0.092
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.901	0.099
M15-M19 Arthrosis	0.898	0.102
M24.1 Other articular cartilage disorders	0.889	0.111
Chapter VI Diseases of the nervous system	0.888	0.112
Z45.2 Adjustment and management of vascular access device	0.887	0.113
L00-L08 Infections of the skin and subcutaneous tissue	0.883	0.117
Z42 Follow-up care involving plastic surgery	0.883	0.117
O80.0 Spontaneous vertex delivery	0.881	0.119
O40 Polyhydramnios	0.881	0.119
Chapter IV Endocrine, nutritional and metabolic diseases	0.878	0.122
M47.9 Spondylosis, unspecified	0.874	0.126
M20.1 Hallux valgus (acquired)	0.868	0.132
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.867	0.133
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.859	0.141
Z42.1 Follow-up care involving plastic surgery of breast	0.857	0.143
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.855	0.145
M24.0 Loose body in joint	0.854	0.145
L02 Cutaneous abscess, furuncle and carbuncle	0.854	0.146
S40-S49 Injuries to the shoulder and upper arm	0.851	0.149
S51 Open wound of forearm	0.850	0.150
M50.3 Other cervical disk degeneration	0.850	0.150
S30 Superficial injury of abdomen, lower back and pelvis	0.849	0.151
M34 Systemic sclerosis	0.846	0.154
M22.8 Other disorders of patella	0.846	0.154
G90-G99 Other disorders of the nervous system	0.844	0.156
S52 Fracture of forearm	0.841	0.159
Z41 Procedures for purposes other than remedying health state	0.840	0.160
M48 Other spondylopathies	0.837	0.163
T79-T79 Certain early complications of trauma	0.836	0.164
O00-O08 Pregnancy with abortive outcome	0.835	0.165
S90-S99 Injuries to the ankle and foot	0.834	0.166
M46 Other inflammatory spondylopathies	0.833	0.167
O36.6 Maternal care for excessive foetal growth	0.832	0.168
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.827	0.173
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.826	0.174
M20.0 Deformity of finger(s)	0.823	0.177
O60-O75 Complications of labour and delivery	0.823	0.177
O85-O92 Complications predominantly related to the puerperium	0.819	0.181
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.819	0.181
M22.2 Patellofemoral disorders	0.818	0.181
Z51 Other medical care	0.818	0.182
E65-E68 Obesity and other hyperalimentation	0.816	0.184
M91-M94 Chondropathies	0.815	0.185
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.814	0.186
O36.8 Maternal care for other specified foetal problems	0.810	0.190
Z47 Other orthopaedic follow-up care	0.810	0.190
M24.16 Other articular cartilage disorders (Lower leg)	0.810	0.190
G99 Other disorders of nervous system in diseases classified elsewhere	0.809	0.191
Z51.8 Other specified medical care	0.807	0.193
S56 Injury of muscle and tendon at forearm level	0.806	0.194
Z45.8 Adjustment and management of other implanted devices	0.803	0.197
O04 Medical abortion	0.802	0.198
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.802	0.198
O34 Maternal care for known or suspected abnormality of pelvic organs	0.801	0.199
M80-M85 Disorders of bone density and structure	0.796	0.204
M60-M63 Disorders of muscles	0.794	0.206
O68 Labour and delivery complicated by foetal stress [distress]	0.794	0.206
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.791	0.209
M21 Other acquired deformities of limbs	0.789	0.211
T92 Sequelae of injuries of upper limb	0.789	0.211
L60-L75 Disorders of skin appendages	0.788	0.212
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.785	0.215
M86-M90 Other osteopathies	0.785	0.215
Chapter XXII Codes for special purposes	0.784	0.216
Z45.1 Adjustment and management of infusion pump	0.783	0.217
G99.2 Myelopathy in diseases classified elsewhere	0.783	0.217
M25 Other joint disorders, not elsewhere classified	0.783	0.217
L40-L45 Papulosquamous disorders	0.783	0.217
M16 Coxarthrosis [arthrosis of hip]	0.782	0.218
S10-S19 Injuries to the neck	0.782	0.218
S31 Open wound of abdomen, lower back and pelvis	0.781	0.219
S20-S29 Injuries to the thorax	0.780	0.220
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.780	0.220
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.776	0.224
M23 Internal derangement of knee	0.775	0.225
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.775	0.225
Z51.4 Preparatory care for treatment, not elsewhere classified	0.775	0.225
E66 Obesity	0.771	0.229
S60-S69 Injuries to the wrist and hand	0.771	0.229
T23 Burn and corrosion of wrist and hand	0.771	0.229
O82 Single delivery by Caesarean section	0.770	0.230
O04.9 Complete or unspecified, without complication	0.770	0.230
O80.9 Single spontaneous delivery, unspecified	0.768	0.232
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.768	0.232
S32 Fracture of lumbar spine and pelvis	0.767	0.233
G00-G09 Inflammatory diseases of the central nervous system	0.766	0.234
M24.5 Contracture of joint	0.762	0.237
M48.0 Spinal stenosis	0.760	0.240
M54 Dorsalgia	0.759	0.241
Z48 Other surgical follow-up care	0.758	0.242
M24.02 Loose body in joint (Upper arm)	0.756	0.244
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.756	0.244
E66.9 Obesity, unspecified	0.756	0.244
O46 Antepartum haemorrhage, not elsewhere classified	0.755	0.245
M50.9 Cervical disk disorder, unspecified	0.754	0.246
Q20-Q28 Congenital malformations of the circulatory system	0.753	0.247
O33 Maternal care for known or suspected disproportion	0.752	0.248
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.749	0.251
Z40 Prophylactic surgery	0.748	0.252
M50.1 Cervical disk disorder with radiculopathy	0.747	0.253
M30 Polyarteritis nodosa and related conditions	0.744	0.256
L60 Nail disorders	0.741	0.259
O36.0 Maternal care for rhesus isoimmunisation	0.741	0.259
M23.4 Loose body in knee	0.741	0.259
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.739	0.261
T91 Sequelae of injuries of neck and trunk	0.736	0.264
S52.5 Fracture of lower end of radius	0.736	0.264
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.733	0.267
S59 Other and unspecified injuries of forearm	0.732	0.268
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.731	0.269
M46.9 Inflammatory spondylopathy, unspecified	0.731	0.269
G50-G59 Nerve, nerve root and plexus disorders	0.729	0.271
S50 Superficial injury of forearm	0.729	0.271
T85 Complications of other internal prosthetic devices, implants and grafts	0.729	0.271
M48.02 Spinal stenosis (Cervical region)	0.728	0.272
M47.1 Other spondylosis with myelopathy	0.728	0.272
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.728	0.272
T46 Poisoning by agents primarily affecting the cardiovascular system	0.727	0.273
T93 Sequelae of injuries of lower limb	0.726	0.274
M16.0 Primary coxarthrosis, bilateral	0.726	0.274
O94-O99 Other obstetric conditions, not elsewhere classified	0.725	0.275
M53 Other dorsopathies, not elsewhere classified	0.724	0.275
M24.4 Recurrent dislocation and subluxation of joint	0.721	0.278
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.720	0.280
M05-M14 Inflammatory polyarthropathies	0.719	0.281
M24.17 Other articular cartilage disorders (Ankle and foot)	0.719	0.281
T79 Certain early complications of trauma, not elsewhere classified	0.719	0.281
M24.8 Other specific joint derangements, not elsewhere classified	0.717	0.283
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M23.49 Loose body in knee-Unspec lig/men	0.716	0.284
L60.0 Ingrowing nail	0.712	0.288
S30.1 Contusion of abdominal wall	0.711	0.289
M34.9 Systemic sclerosis, unspecified	0.711	0.289
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.710	0.289
T66-T78 Other and unspecified effects of external causes	0.710	0.290
M49 Spondylopathies in diseases classified elsewhere	0.710	0.290
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.290
M17 Gonarthrosis [arthrosis of knee]	0.709	0.291
O66 Other obstructed labour	0.708	0.292
O36.4 Maternal care for intra-uterine death	0.707	0.293
G80-G83 Cerebral palsy and other paralytic syndromes	0.705	0.295
M40-M43 Deforming dorsopathies	0.704	0.296
O42 Premature rupture of membranes	0.703	0.297
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.703	0.297
M00-M03 Infectious arthropathies	0.703	0.297
O34.2 Maternal care due to uterine scar from previous surgery	0.702	0.298
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.701	0.299
S37 Injury of urinary and pelvic organs	0.701	0.299
S36 Injury of intra-abdominal organs	0.701	0.299
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.701	0.299
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.701	0.299
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.701	0.299
O36.3 Maternal care for signs of foetal hypoxia	0.701	0.299
T59 Toxic effect of other gases, fumes and vapours	0.700	0.300
O43 Placental disorders	0.698	0.302
S51.9 Open wound of forearm, part unspecified	0.698	0.302
T63 Toxic effect of contact with venomous animals	0.697	0.303
M50.8 Other cervical disk disorders	0.697	0.303
M20.4 Other hammer toe(s) (acquired)	0.695	0.305
M24.9 Joint derangement, unspecified	0.695	0.305
M24.7 Protrusio acetabuli	0.695	0.305
M24.6 Ankylosis of joint	0.695	0.305
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.695	0.305
S58 Traumatic amputation of forearm	0.693	0.307
S57 Crushing injury of forearm	0.693	0.307
S55 Injury of blood vessels at forearm level	0.693	0.307
S54 Injury of nerves at forearm level	0.693	0.307
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.693	0.307
L40 Psoriasis	0.691	0.309
T15-T19 Effects of foreign body entering through natural orifice	0.690	0.310
S66 Injury of muscle and tendon at wrist and hand level	0.689	0.311
Z48.0 Attention to surgical dressings and sutures	0.688	0.312
M24.2 Disorder of ligament	0.687	0.313
E50-E64 Other nutritional deficiencies	0.686	0.313
O84 Multiple delivery	0.686	0.314
O83 Other assisted single delivery	0.686	0.314
E40-E46 Malnutrition	0.685	0.315
M25.4 Effusion of joint	0.685	0.315
S70-S79 Injuries to the hip and thigh	0.685	0.315
O45 Premature separation of placenta [abruptio placentae]	0.685	0.315
O31 Complications specific to multiple gestation	0.685	0.315
T43.0 Tricyclic and tetracyclic antidepressants	0.684	0.316
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.683	0.317
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.682	0.317
M19 Other arthrosis	0.682	0.318
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.680	0.320
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.679	0.321
E10-E14 Diabetes mellitus	0.679	0.321
O41 Other disorders of amniotic fluid and membranes	0.678	0.322
T92.2 Sequelae of fracture at wrist and hand level	0.677	0.323
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.676	0.323
L20-L30 Dermatitis and eczema	0.675	0.325
T13 Other injuries of lower limb, level unspecified	0.675	0.325
S43.0 Dislocation of shoulder joint	0.675	0.325
M47.96 Spondylosis, unspecified (Lumbar region)	0.674	0.326
M47.2 Other spondylosis with radiculopathy	0.674	0.326
T23.3 Burn of third degree of wrist and hand	0.672	0.328
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.672	0.328
T56 Toxic effect of metals	0.672	0.328
S43.1 Dislocation of acromioclavicular joint	0.672	0.328
T83.1 Mechanical complication of other urinary devices and implants	0.672	0.328
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.671	0.329
O86 Other puerperal infections	0.671	0.329
L03 Cellulitis	0.670	0.330
O35 Maternal care for known or suspected foetal abnormality and damage	0.670	0.330
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.669	0.331
O16 Unspecified maternal hypertension	0.668	0.332
M34.8 Other forms of systemic sclerosis	0.668	0.332
M25.6 Stiffness of joint, not elsewhere classified	0.668	0.332
T20 Burn and corrosion of head and neck	0.668	0.332
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.667	0.333
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.667	0.333
T41 Poisoning by anaesthetics and therapeutic gases	0.667	0.333
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.667	0.333
T36 Poisoning by systemic antibiotics	0.667	0.333
M22.3 Other derangements of patella	0.666	0.334
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.664	0.336
S60 Superficial injury of wrist and hand	0.663	0.337
S91 Open wound of ankle and foot	0.663	0.337
G95 Other diseases of spinal cord	0.662	0.338
L08 Other local infections of skin and subcutaneous tissue	0.662	0.338
O80.8 Other single spontaneous delivery	0.662	0.338
O80.1 Spontaneous breech delivery	0.662	0.338
S52.50 Fracture of lower end of radius (closed)	0.661	0.339
L10-L14 Bullous disorders	0.661	0.339
M47.0 Anterior spinal and vertebral artery compression syndromes	0.660	0.340
M94 Other disorders of cartilage	0.660	0.340
M22.1 Recurrent subluxation of patella	0.659	0.340
M22.9 Disorder of patella, unspecified	0.659	0.340
M22.0 Recurrent dislocation of patella	0.659	0.340
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.659	0.341
O36.2 Maternal care for hydrops foetalis	0.659	0.341
O36.1 Maternal care for other isoimmunisation	0.659	0.341
G90 Disorders of autonomic nervous system	0.659	0.341
S52.1 Fracture of upper end of radius	0.658	0.342
S51.7 Multiple open wounds of forearm	0.658	0.342
Z44 Fitting and adjustment of external prosthetic device	0.657	0.342
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.657	0.343
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.657	0.343
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.657	0.343
T94 Sequelae of injuries involving multiple and unspecified body regions	0.657	0.343
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.657	0.343
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.654	0.346
Q38-Q45 Other congenital malformations of the digestive system	0.653	0.347
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.653	0.347
M24.07 Loose body in joint (Ankle and foot)	0.653	0.347
Z45.9 Adjustment and management of unspecified implanted device	0.652	0.347
Z45.3 Adjustment and management of implanted hearing device	0.652	0.347
S51.0 Open wound of elbow	0.652	0.348
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.651	0.349
T25 Burn and corrosion of ankle and foot	0.651	0.349
T21 Burn and corrosion of trunk	0.651	0.349
S51.8 Open wound of other parts of forearm	0.651	0.349
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.650	0.350
Q21 Congenital malformations of cardiac septa	0.650	0.350
M24.13 Other articular cartilage disorders (Forearm)	0.649	0.351
M89 Other disorders of bone	0.649	0.351
S52.4 Fracture of shafts of both ulna and radius	0.648	0.352
S30.2 Contusion of external genital organs	0.648	0.352
M62 Other disorders of muscle	0.647	0.353
M25.46 Effusion of joint (Lower leg)	0.646	0.354
T95 Sequelae of burns, corrosions and frostbite	0.646	0.354
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.646	0.354
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.646	0.354
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.646	0.354
G96 Other disorders of central nervous system	0.646	0.354
M18 Arthrosis of first carpometacarpal joint	0.646	0.354
G91 Hydrocephalus	0.645	0.355
T83.0 Mechanical complication of urinary (indwelling) catheter	0.645	0.355
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.644	0.356
M15 Polyarthrosis	0.644	0.356
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.642	0.358
S96 Injury of muscle and tendon at ankle and foot level	0.640	0.360
T86 Failure and rejection of transplanted organs and tissues	0.639	0.361
S90 Superficial injury of ankle and foot	0.639	0.361
M20.5 Other deformities of toe(s) (acquired)	0.638	0.362
M24.19 Other articular cartilage disorders (Site unspecified)	0.637	0.363
M24.18 Other articular cartilage disorders (Other)	0.637	0.363
M24.14 Other articular cartilage disorders (Hand)	0.637	0.363
M24.12 Other articular cartilage disorders (Upper arm)	0.637	0.363
M24.10 Other articular cartilage disorders (Multiple sites)	0.637	0.363
Q50-Q56 Congenital malformations of genital organs	0.636	0.364
O44 Placenta praevia	0.636	0.364
M21.2 Flexion deformity	0.636	0.364
E11 Non-insulin-dependent diabetes mellitus	0.636	0.364
L03.8 Cellulitis of other sites	0.635	0.365
L04 Acute lymphadenitis	0.633	0.366
L01 Impetigo	0.633	0.366
L00 Staphylococcal scalded skin syndrome	0.633	0.366
Z42.9 Follow-up care involving plastic surgery, unspecified	0.633	0.367
Z42.8 Follow-up care involving plastic surgery of other body part	0.633	0.367
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.633	0.367
O92 Other disorders of breast and lactation associated with childbirth	0.632	0.368
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.632	0.368
S41 Open wound of shoulder and upper arm	0.632	0.368
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.631	0.368
M47.92 Spondylosis, unspecified (Cervical region)	0.631	0.369
S52.6 Fracture of lower end of both ulna and radius	0.631	0.369
M16.3 Other dysplastic coxarthrosis	0.630	0.370
Z48.9 Surgical follow-up care, unspecified	0.630	0.370
M17.9 Gonarthrosis, unspecified	0.630	0.370
M84 Disorders of continuity of bone	0.629	0.371
O71 Other obstetric trauma	0.628	0.371
L40.5 Arthropathic psoriasis	0.628	0.372
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.628	0.372
M45 Ankylosing spondylitis	0.627	0.372
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.627	0.373
O72 Postpartum haemorrhage	0.627	0.373
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.627	0.373
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.627	0.373
M47.94 Spondylosis, unspecified (Thoracic region)	0.627	0.373
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.627	0.373
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.627	0.373
O82.9 Delivery by Caesarean section, unspecified	0.627	0.373
T42.4 Benzodiazepines	0.626	0.374
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.626	0.374
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.624	0.376
O81 Single delivery by forceps and vacuum extractor	0.624	0.376
Z47.9 Orthopaedic follow-up care, unspecified	0.624	0.376
O20-O29 Other maternal disorders predominantly related to pregnancy	0.623	0.377
M85 Other disorders of bone density and structure	0.622	0.378
L73 Other follicular disorders	0.622	0.378
T65 Toxic effect of other and unspecified substances	0.621	0.378
T62 Toxic effect of other noxious substances eaten as food	0.621	0.378
T61 Toxic effect of noxious substances eaten as seafood	0.621	0.378
T60 Toxic effect of pesticides	0.621	0.378
T57 Toxic effect of other inorganic substances	0.621	0.378
T54 Toxic effect of corrosive substances	0.621	0.378
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.621	0.378
T52 Toxic effect of organic solvents	0.621	0.378
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.621	0.378
T58 Toxic effect of carbon monoxide	0.621	0.378
T55 Toxic effect of soaps and detergents	0.621	0.378
S32.4 Fracture of acetabulum	0.621	0.379
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.621	0.379
S10 Superficial injury of neck	0.620	0.380
S40 Superficial injury of shoulder and upper arm	0.620	0.380
S22 Fracture of rib(s), sternum and thoracic spine	0.620	0.380
T45.0 Antiallergic and antiemetic drugs	0.618	0.382
M47.99 Spondylosis, unspecified (Site unspecified)	0.618	0.382
M23.6 Other spontaneous disruption of ligament(s) of knee	0.617	0.383
T87 Complications peculiar to reattachment and amputation	0.617	0.383
L71 Rosacea	0.616	0.384
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.616	0.384
Q35-Q37 Cleft lip and cleft palate	0.616	0.384
Q30-Q34 Congenital malformations of the respiratory system	0.616	0.384
S11 Open wound of neck	0.615	0.384
Z54 Convalescence	0.615	0.385
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.615	0.385
M24.54 Contracture of joint (Hand)	0.614	0.386
M23.0 Cystic meniscus	0.614	0.386
M24.09 Loose body in joint (Site unspecified)	0.613	0.387
M24.08 Loose body in joint (Other)	0.613	0.387
M24.06 Loose body in joint-Lower leg	0.613	0.387
M24.05 Loose body in joint (Pelvic region and thigh)	0.613	0.387
M24.04 Loose body in joint (Hand)	0.613	0.387
M24.03 Loose body in joint (Forearm)	0.613	0.387
M24.01 Loose body in joint (Shoulder region)	0.613	0.387
M24.00 Loose body in joint (Multiple sites)	0.613	0.387
O46.9 Antepartum haemorrhage, unspecified	0.613	0.387
T42.1 Iminostilbenes	0.612	0.388
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.612	0.388
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.612	0.388
T51 Toxic effect of alcohol	0.611	0.389
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.611	0.389
M24.11 Other articular cartilage disorders (Shoulder region)	0.611	0.389
Z51.3 Blood transfusion without reported diagnosis	0.610	0.390
M70-M79 Other soft tissue disorders	0.610	0.390
S48 Traumatic amputation of shoulder and upper arm	0.610	0.390
S45 Injury of blood vessels at shoulder and upper arm level	0.610	0.390
S44 Injury of nerves at shoulder and upper arm level	0.610	0.390
S47 Crushing injury of shoulder and upper arm	0.610	0.390
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.610	0.390
T43.3 Phenothiazine antipsychotics and neuroleptics	0.610	0.390
Z45.0 Adjustment and management of cardiac pacemaker	0.610	0.390
M17.0 Primary gonarthrosis, bilateral	0.610	0.390
M16.7 Other secondary coxarthrosis	0.609	0.391
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.609	0.391
O82.0 Delivery by elective Caesarean section	0.609	0.391
M21.3 Wrist or foot drop (acquired)	0.608	0.391
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.608	0.392
G35-G37 Demyelinating diseases of the central nervous system	0.608	0.392
M92 Other juvenile osteochondrosis	0.607	0.393
S31.0 Open wound of lower back and pelvis	0.607	0.393
M34.2 Systemic sclerosis induced by drugs and chemicals	0.607	0.393
M34.0 Progressive systemic sclerosis	0.607	0.393
E00-E07 Disorders of thyroid gland	0.607	0.393
S68 Traumatic amputation of wrist and hand	0.607	0.393
O33.9 Maternal care for disproportion, unspecified	0.606	0.394
T84.0 Mechanical complication of internal joint prosthesis	0.606	0.394
E55 Vitamin D deficiency	0.606	0.394
O36.9 Maternal care for foetal problem, unspecified	0.606	0.394
T85.2 Mechanical complication of intraocular lens	0.605	0.395
S99 Other and unspecified injuries of ankle and foot	0.605	0.395
M81 Osteoporosis without pathological fracture	0.605	0.395
G94 Other disorders of brain in diseases classified elsewhere	0.605	0.395
G98 Other disorders of nervous system, not elsewhere classified	0.605	0.395
G92 Toxic encephalopathy	0.605	0.395
M47.8 Other spondylosis	0.605	0.395
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.605	0.395
O87 Venous complications in the puerperium	0.604	0.396
T98 Sequelae of other and unspecified effects of external causes	0.604	0.396
O36.5 Maternal care for poor foetal growth	0.604	0.396
E20-E35 Disorders of other endocrine glands	0.603	0.397
S52.9 Fracture of forearm, part unspecified	0.603	0.397
S52.8 Fracture of other parts of forearm	0.603	0.397
S52.7 Multiple fractures of forearm	0.603	0.397
S52.3 Fracture of shaft of radius	0.603	0.397
S52.2 Fracture of shaft of ulna	0.603	0.397
M23.9 Internal derangement of knee, unspecified	0.603	0.397
G70-G73 Diseases of myoneural junction and muscle	0.603	0.397
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.602	0.398
Z41.8 Other procedures for purposes other than remedying health state	0.602	0.398
Z41.3 Ear piercing	0.602	0.398
Z41.2 Routine and ritual circumcision	0.602	0.398
Z41.0 Hair transplant	0.602	0.398
L60.9 Nail disorder, unspecified	0.602	0.398
Q24 Other congenital malformations of heart	0.602	0.398
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.601	0.399
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.601	0.399
S92 Fracture of foot, except ankle	0.601	0.399
S31.8 Open wound of other and unspecified parts of abdomen	0.601	0.399
Z46 Fitting and adjustment of other devices	0.601	0.399
M48.9 Spondylopathy, unspecified	0.600	0.399
M48.8 Other specified spondylopathies	0.600	0.399
M48.4 Fatigue fracture of vertebra	0.600	0.399
M48.3 Traumatic spondylopathy	0.600	0.399
M48.2 Kissing spine	0.600	0.399
M48.1 Ankylosing hyperostosis [Forestier]	0.600	0.399
M20.6 Acquired deformity of toe(s), unspecified	0.600	0.400
Q28 Other congenital malformations of circulatory system	0.600	0.400
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.599	0.401
O08 Complications following abortion and ectopic and molar pregnancy	0.598	0.401
O07 Failed attempted abortion	0.598	0.401
O06 Unspecified abortion	0.598	0.401
O05 Other abortion	0.598	0.401
O01 Hydatidiform mole	0.598	0.401
T93.8 Sequelae of other specified injuries of lower limb	0.598	0.402
M54.3 Sciatica	0.598	0.402
S98 Traumatic amputation of ankle and foot	0.598	0.402
S97 Crushing injury of ankle and foot	0.598	0.402
S95 Injury of blood vessels at ankle and foot level	0.598	0.402
S94 Injury of nerves at ankle and foot level	0.598	0.402
M14 Arthropathies in other diseases classified elsewhere	0.597	0.402
M46.8 Other specified inflammatory spondylopathies	0.597	0.403
M46.5 Other infective spondylopathies	0.597	0.403
M46.4 Discitis, unspecified	0.597	0.403
M46.3 Infection of intervertebral disk (pyogenic)	0.597	0.403
M46.2 Osteomyelitis of vertebra	0.597	0.403
M46.1 Sacro-iliitis, not elsewhere classified	0.597	0.403
M46.0 Spinal enthesopathy	0.597	0.403
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.597	0.403
M93 Other osteochondropathies	0.597	0.403
G30-G32 Other degenerative diseases of the nervous system	0.596	0.404
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.596	0.404
T91.8 Sequelae of other specified injuries of neck and trunk	0.595	0.405
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.594	0.406
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.594	0.406
S50.8 Other superficial injuries of forearm	0.594	0.406
G03 Meningitis due to other and unspecified causes	0.594	0.406
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.594	0.406
E11.9 Without complications	0.594	0.406
S29 Other and unspecified injuries of thorax	0.593	0.406
G01 Meningitis in bacterial diseases classified elsewhere	0.593	0.407
O15 Eclampsia	0.592	0.408
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.592	0.408

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations