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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2530710
log Bayes Factor = 43.7096
Chromosome 6   position 30,940,387  (GRCh37) Explore rs2530710 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.011 0.989
E78.0 Pure hypercholesterolaemia
0.000 0.012 0.988
E11 Non-insulin-dependent diabetes mellitus
0.000 0.012 0.988
E14.9 Without complications
0.000 0.014 0.986
E70-E90 Metabolic disorders
0.000 0.014 0.986
E78.5 Hyperlipidaemia, unspecified
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
G35 Multiple sclerosis
0.978 0.022 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.024 0.976
E11.9 Without complications
0.000 0.031 0.969
E10.1 With ketoacidosis
0.000 0.033 0.967
I20-I25 Ischaemic heart diseases
0.000 0.041 0.959
I25 Chronic ischaemic heart disease
0.000 0.047 0.953
I24 Other acute ischaemic heart diseases
0.000 0.049 0.951
E78.2 Mixed hyperlipidaemia
0.000 0.053 0.947
I22 Subsequent myocardial infarction
0.000 0.060 0.940
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.063 0.937
E50-E64 Other nutritional deficiencies
0.000 0.072 0.928
E10.4 With neurological complications
0.000 0.077 0.923
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.087 0.913
E11.0 With coma
0.000 0.090 0.910
E10.2 With renal complications
0.000 0.096 0.904
E07 Other disorders of thyroid
0.000 0.096 0.903
L40.0 Psoriasis vulgaris
0.000 0.106 0.894
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.110 0.890
E61 Deficiency of other nutrient elements
0.000 0.112 0.888
I21 Acute myocardial infarction
0.000 0.114 0.886
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.119 0.881
E78.8 Other disorders of lipoprotein metabolism
0.000 0.128 0.872
I25.2 Old myocardial infarction
0.000 0.128 0.872
E07.9 Disorder of thyroid, unspecified
0.000 0.145 0.855
I21.4 Acute subendocardial myocardial infarction
0.000 0.147 0.853
E61.1 Iron deficiency
0.000 0.149 0.851
I24.8 Other forms of acute ischaemic heart disease
0.000 0.153 0.847
E10.8 With unspecified complications
0.000 0.156 0.844
E10.0 With coma
0.000 0.157 0.843
E14.3 With ophthalmic complications
0.000 0.157 0.843
E11.5 With peripheral circulatory complications
0.000 0.163 0.837
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.168 0.832
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.180 0.820
E11.1 With ketoacidosis
0.000 0.181 0.819
E20-E35 Disorders of other endocrine glands
0.000 0.193 0.807
E10.5 With peripheral circulatory complications
0.000 0.207 0.793
I21.9 Acute myocardial infarction, unspecified
0.000 0.212 0.788
E16.1 Other hypoglycaemia
0.000 0.220 0.780
E05.8 Other thyrotoxicosis
0.000 0.228 0.772
E55 Vitamin D deficiency
0.000 0.229 0.771
E10.6 With other specified complications
0.000 0.231 0.769
I25.5 Ischaemic cardiomyopathy
0.000 0.236 0.764
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.238 0.762
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.248 0.752
E14.1 With ketoacidosis
0.000 0.248 0.751
I23 Certain current complications following acute myocardial infarction
0.000 0.253 0.747
I25.3 Aneurysm of heart
0.000 0.256 0.744
E11.6 With other specified complications
0.000 0.264 0.736
G35-G37 Demyelinating diseases of the central nervous system
0.736 0.264 0.000
L40.1 Generalised pustular psoriasis
0.000 0.273 0.727
E14.4 With neurological complications
0.000 0.273 0.727
L40-L45 Papulosquamous disorders
0.000 0.274 0.726
I24.1 Dressler's syndrome
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.283 0.716
E03.5 Myxoedema coma
0.000 0.284 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.715
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.715
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E78.1 Pure hyperglyceridaemia
0.000 0.287 0.713
E14.8 With unspecified complications
0.000 0.287 0.713
E14.7 With multiple complications
0.000 0.287 0.713
E14.6 With other specified complications
0.000 0.287 0.713
E14.5 With peripheral circulatory complications
0.000 0.287 0.713
E14.2 Withrenal complications
0.000 0.287 0.713
E14.0 With coma
0.000 0.287 0.713
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.709
E11.7 With multiple complications
0.000 0.291 0.708
I10 Essential (primary) hypertension
0.000 0.292 0.708
I10-I15 Hypertensive diseases
0.000 0.292 0.708
E79 Disorders of purine and pyrimidine metabolism
0.000 0.293 0.707
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.707
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.293 0.707
E72 Other disorders of amino-acid metabolism
0.000 0.293 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.707
E70 Disorders of aromatic amino-acid metabolism
0.000 0.293 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.707
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E23 Hypofunction and other disorders of pituitary gland
0.000 0.298 0.702
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.298 0.702
Chapter IX Diseases of the circulatory system
0.000 0.298 0.702
E85 Amyloidosis
0.000 0.303 0.697
E24 Cushing's syndrome
0.000 0.303 0.697
E61.2 Magnesium deficiency
0.000 0.304 0.696
E83 Disorders of mineral metabolism
0.622 0.306 0.072
E11.4 With neurological complications
0.000 0.307 0.693
L43 Lichen planus
0.000 0.312 0.688
E13 Other specified diabetes mellitus
0.000 0.315 0.685
I25.6 Silent myocardial ischaemia
0.000 0.317 0.683
I25.1 Atherosclerotic heart disease
0.000 0.322 0.678
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.323 0.677
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.325 0.674
G37 Other demyelinating diseases of central nervous system
0.674 0.326 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.326 0.674
E74 Other disorders of carbohydrate metabolism
0.000 0.333 0.667
E11.2 With renal complications
0.000 0.334 0.666
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.334 0.665
E63 Other nutritional deficiencies
0.000 0.334 0.665
E56 Other vitamin deficiencies
0.000 0.334 0.665
E51 Thiamine deficiency
0.000 0.334 0.665
E50 Vitamin A deficiency
0.000 0.334 0.665
E60 Dietary zinc deficiency
0.000 0.334 0.665
E59 Dietary selenium deficiency
0.000 0.334 0.665
E58 Dietary calcium deficiency
0.000 0.334 0.665
E54 Ascorbic acid deficiency
0.000 0.334 0.665
E52 Niacin deficiency [pellagra]
0.000 0.334 0.665
E84 Cystic fibrosis
0.000 0.340 0.660
E55.9 Vitamin D deficiency, unspecified
0.000 0.342 0.658
E78.4 Other hyperlipidaemia
0.000 0.343 0.657
E06 Thyroiditis
0.000 0.344 0.656
L43.9 Lichen planus, unspecified
0.000 0.346 0.654
E07.1 Dyshormogenetic goitre
0.000 0.352 0.648
E07.0 Hypersecretion of calcitonin
0.000 0.352 0.648
E21.3 Hyperparathyroidism, unspecified
0.000 0.354 0.646
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.354 0.646
E73 Lactose intolerance
0.000 0.356 0.644
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.358 0.642
E61.9 Deficiency of nutrient element, unspecified
0.000 0.363 0.637
E61.8 Deficiency of other specified nutrient elements
0.000 0.363 0.637
E61.7 Deficiency of multiple nutrient elements
0.000 0.363 0.637
E61.6 Vanadium deficiency
0.000 0.363 0.637
E61.5 Molybdenum deficiency
0.000 0.363 0.637
E61.4 Chromium deficiency
0.000 0.363 0.637
E61.3 Manganese deficiency
0.000 0.363 0.637
E61.0 Copper deficiency
0.000 0.363 0.637
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.365 0.635
I25.4 Coronary artery aneurysm
0.000 0.368 0.632
L40.8 Other psoriasis
0.000 0.370 0.630
E40-E46 Malnutrition
0.000 0.372 0.628
I22.8 Subsequent myocardial infarction of other sites
0.000 0.375 0.625
E23.0 Hypopituitarism
0.000 0.379 0.621
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.382 0.618
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.387 0.613
I15 Secondary hypertension
0.000 0.390 0.609
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.394 0.605
E24.9 Cushing's syndrome, unspecified
0.000 0.402 0.598
I74 Arterial embolism and thrombosis
0.000 0.403 0.597
I23.8 Other current complications following acute myocardial infarction
0.000 0.405 0.595
I05-I09 Chronic rheumatic heart diseases
0.000 0.406 0.594
E83.3 Disorders of phosphorus metabolism
0.576 0.407 0.017
G37.8 Other specified demyelinating diseases of central nervous system
0.587 0.413 0.000
E28 Ovarian dysfunction
0.000 0.414 0.586
E03.8 Other specified hypothyroidism
0.000 0.417 0.582
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.422 0.578
E32 Diseases of thymus
0.000 0.422 0.578
E31 Polyglandular dysfunction
0.000 0.422 0.578
E30 Disorders of puberty, not elsewhere classified
0.000 0.422 0.578
E25 Adrenogenital disorders
0.000 0.422 0.578
E88 Other metabolic disorders
0.000 0.422 0.578
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.430 0.570
G37.9 Demyelinating disease of central nervous system, unspecified
0.568 0.432 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.438 0.561
I12 Hypertensive renal disease
0.000 0.442 0.558
I70 Atherosclerosis
0.000 0.443 0.557
E89.3 Postprocedural hypopituitarism
0.000 0.443 0.557
E55.0 Rickets, active
0.000 0.447 0.553
E29 Testicular dysfunction
0.000 0.450 0.550
E11.8 With unspecified complications
0.000 0.452 0.548
I74.5 Embolism and thrombosis of iliac artery
0.000 0.455 0.545
E07.8 Other specified disorders of thyroid
0.000 0.458 0.542
E24.2 Drug-induced Cushing's syndrome
0.000 0.460 0.540
E85.9 Amyloidosis, unspecified
0.000 0.461 0.539
E22 Hyperfunction of pituitary gland
0.000 0.461 0.539
L43.8 Other lichen planus
0.000 0.463 0.537
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.464 0.536
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.464 0.536
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.464 0.536
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.464 0.536
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.464 0.536
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.464 0.536
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.464 0.536
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.534 0.466 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.467 0.533
E26 Hyperaldosteronism
0.000 0.469 0.530
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.471 0.529
G36 Other acute disseminated demyelination
0.528 0.472 0.000
I11 Hypertensive heart disease
0.000 0.473 0.526
E23.2 Diabetes insipidus
0.000 0.474 0.526
I15.1 Hypertension secondary to other renal disorders
0.000 0.476 0.524
E20 Hypoparathyroidism
0.000 0.477 0.523
L44 Other papulosquamous disorders
0.000 0.480 0.520
L41 Parapsoriasis
0.000 0.480 0.520
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.480 0.520
E23.7 Disorder of pituitary gland, unspecified
0.000 0.483 0.517
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
I05 Rheumatic mitral valve diseases
0.000 0.486 0.514
I13 Hypertensive heart and renal disease
0.000 0.493 0.507
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.493 0.507
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.493 0.507
E70.3 Albinism
0.000 0.493 0.507
E70.2 Disorders of tyrosine metabolism
0.000 0.493 0.507
E70.1 Other hyperphenylalaninaemias
0.000 0.493 0.507
E70.0 Classical phenylketonuria
0.000 0.493 0.507
E71.3 Disorders of fatty-acid metabolism
0.000 0.493 0.507
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.493 0.507
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.493 0.507
E71.0 Maple-syrup-urine disease
0.000 0.493 0.507
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.493 0.507
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.493 0.507
E72.5 Disorders of glycine metabolism
0.000 0.493 0.507
E72.4 Disorders of ornithine metabolism
0.000 0.493 0.507
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.493 0.507
E72.2 Disorders of urea cycle metabolism
0.000 0.493 0.507
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.493 0.507
E72.0 Disorders of amino-acid transport
0.000 0.493 0.507
E75.6 Lipid storage disorder, unspecified
0.000 0.493 0.507
E75.5 Other lipid storage disorders
0.000 0.493 0.507
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.493 0.507
E75.3 Sphingolipidosis, unspecified
0.000 0.493 0.507
E75.2 Other sphingolipidosis
0.000 0.493 0.507
E75.1 Other gangliosidosis
0.000 0.493 0.507
E75.0 GM2 gangliosidosis
0.000 0.493 0.507
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.493 0.507
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.493 0.507
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.493 0.507
E76.2 Other mucopolysaccharidoses
0.000 0.493 0.507
E76.1 Mucopolysaccharidosis, type II
0.000 0.493 0.507
E76.0 Mucopolysaccharidosis, type I
0.000 0.493 0.507
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.493 0.507
E77.8 Other disorders of glycoprotein metabolism
0.000 0.493 0.507
E77.1 Defects in glycoprotein degradation
0.000 0.493 0.507
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.493 0.507
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.493 0.507
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.493 0.507
E79.1 Lesch-Nyhan syndrome
0.000 0.493 0.507
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.493 0.507
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.496 0.504
E23.1 Drug-induced hypopituitarism
0.000 0.496 0.504
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.496 0.503
E21.4 Other specified disorders of parathyroid gland
0.000 0.496 0.503
E21.2 Other hyperparathyroidism
0.000 0.496 0.503
I70.0 Atherosclerosis of aorta
0.000 0.499 0.501
E89.2 Postprocedural hypoparathyroidism
0.000 0.499 0.501
E85.8 Other amyloidosis
0.000 0.500 0.500
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.500 0.500
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.500 0.500
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.500 0.500
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.500 0.500 0.000
E24.8 Other Cushing's syndrome
0.000 0.500 0.500
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.500 0.500
E24.3 Ectopic ACTH syndrome
0.000 0.500 0.500
E24.1 Nelson's syndrome
0.000 0.500 0.500
E24.0 Pituitary-dependent Cushing's disease
0.000 0.500 0.500
E83.9 Disorder of mineral metabolism, unspecified
0.446 0.503 0.052
E83.8 Other disorders of mineral metabolism
0.446 0.503 0.052
E83.2 Disorders of zinc metabolism
0.446 0.503 0.052
E83.0 Disorders of copper metabolism
0.446 0.503 0.052
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.505 0.495
L43.3 Subacute (active) lichen planus
0.000 0.506 0.493
L43.2 Lichenoid drug reaction
0.000 0.506 0.493
L43.1 Bullous lichen planus
0.000 0.506 0.493
L43.0 Hypertrophic lichen planus
0.000 0.506 0.493
E13.8 With unspecified complications
0.000 0.509 0.491
E13.7 With multiple complications
0.000 0.509 0.491
E13.6 With other specified complications
0.000 0.509 0.491
E13.5 With peripheral circulatory complications
0.000 0.509 0.491
E13.4 With neurological complications
0.000 0.509 0.491
E13.3 With ophthalmic complications
0.000 0.509 0.491
E13.2 With renal complications
0.000 0.509 0.491
E13.1 With ketoacidosis
0.000 0.509 0.491
E13.0 With coma
0.000 0.509 0.491
I15.9 Seconday hypertension, unspecified
0.000 0.516 0.484
E28.2 Polycystic ovarian syndrome
0.000 0.516 0.484
G37.5 Concentric sclerosis [Balo]
0.483 0.517 0.000
G37.4 Subacute necrotising myelitis
0.483 0.517 0.000
G37.2 Central pontine myelinolysis
0.483 0.517 0.000
G37.1 Central demyelination of corpus callosum
0.483 0.517 0.000
G37.0 Diffuse sclerosis
0.483 0.517 0.000
I00-I02 Acute rheumatic fever
0.000 0.517 0.483
E23.6 Other disorders of pituitary gland
0.000 0.517 0.482
E85.3 Secondary systemic amyloidosis
0.000 0.520 0.480
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.521 0.478
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.521 0.478
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.521 0.478
E74.2 Disorders of galactose metabolism
0.000 0.521 0.478
E74.1 Disorders of fructose metabolism
0.000 0.521 0.478
E74.0 Glycogen storage disease
0.000 0.521 0.478
E50.9 Vitamin A deficiency, unspecified
0.000 0.523 0.477
E50.8 Other manifestations of vitamin A deficiency
0.000 0.523 0.477
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.523 0.477
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.523 0.477
E50.5 Vitamin A deficiency with night blindness
0.000 0.523 0.477
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.523 0.477
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.523 0.477
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.523 0.477
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.523 0.477
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.523 0.477
E51.9 Thiamine deficiency, unspecified
0.000 0.523 0.477
E51.8 Other manifestations of thiamine deficiency
0.000 0.523 0.477
E51.2 Wernicke's encephalopathy
0.000 0.523 0.477
E51.1 Beriberi
0.000 0.523 0.477
E56.9 Vitamin deficiency, unspecified
0.000 0.523 0.477
E56.8 Deficiency of other vitamins
0.000 0.523 0.477
E56.1 Deficiency of vitamin K
0.000 0.523 0.477
E56.0 Deficiency of vitamin E
0.000 0.523 0.477
E63.9 Nutritional deficiency, unspecified
0.000 0.523 0.477
E63.8 Other specified nutritional deficiencies
0.000 0.523 0.477
E63.1 Imbalance of constituents of food intake
0.000 0.523 0.477
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.523 0.477
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.523 0.477
E64.8 Sequelae of other nutritional deficiencies
0.000 0.523 0.477
E64.3 Sequelae of rickets
0.000 0.523 0.477
E64.2 Sequelae of vitamin C deficiency
0.000 0.523 0.477
E64.1 Sequelae of vitamin A deficiency
0.000 0.523 0.477
E64.0 Sequelae of protein-energy malnutrition
0.000 0.523 0.477
E84.8 Cystic fibrosis with other manifestations
0.000 0.527 0.473
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.527 0.473
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.527 0.473
E06.5 Other chronic thyroiditis
0.000 0.529 0.471
E06.4 Drug-induced thyroiditis
0.000 0.529 0.471
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.529 0.471
E06.1 Subacute thyroiditis
0.000 0.529 0.471
E06.0 Acute thyroiditis
0.000 0.529 0.471
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.531 0.469
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.537 0.463
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.537 0.463
E89.5 Postprocedural testicular hypofunction
0.000 0.537 0.463
E89.1 Postprocedural hypoinsulinaemia
0.000 0.537 0.463
E85.4 Organ-limited amyloidosis
0.000 0.537 0.463
E73.8 Other lactose intolerance
0.000 0.538 0.462
E73.1 Secondary lactase deficiency
0.000 0.538 0.462
E73.0 Congenital lactase deficiency
0.000 0.538 0.462
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.539 0.461
E06.3 Autoimmune thyroiditis
0.000 0.539 0.461
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.539 0.461
E13.9 Without complications
0.000 0.540 0.459
I12.9 Hypertensive renal disease without renal failure
0.000 0.544 0.456
I09 Other rheumatic heart diseases
0.000 0.548 0.452
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.550 0.450
E45 Retarded development following protein-energy malnutrition
0.000 0.550 0.450
E43 Unspecified severe protein-energy malnutrition
0.000 0.550 0.450
E42 Marasmic kwashiorkor
0.000 0.550 0.450
E41 Nutritional marasmus
0.000 0.550 0.450
E40 Kwashiorkor
0.000 0.550 0.450
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.551 0.449
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.552 0.448
E89.4 Postprocedural ovarian failure
0.000 0.553 0.447
E34 Other endocrine disorders
0.000 0.553 0.446
I71 Aortic aneurysm and dissection
0.000 0.555 0.445
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.561 0.438
I15.8 Other secondary hypertension
0.000 0.563 0.437
I15.2 Hypertension secondary to endocrine disorders
0.000 0.563 0.437
I08 Multiple valve diseases
0.000 0.565 0.435
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.567 0.433
I74.8 Embolism and thrombosis of other arteries
0.000 0.572 0.428
E84.9 Cystic fibrosis, unspecified
0.000 0.574 0.426
L42 Pityriasis rosea
0.000 0.577 0.422
I05.2 Mitral stenosis with insufficiency
0.000 0.577 0.422
E06.9 Thyroiditis, unspecified
0.000 0.578 0.422
E28.9 Ovarian dysfunction, unspecified
0.000 0.580 0.420
E28.8 Other ovarian dysfunction
0.000 0.580 0.420
E28.1 Androgen excess
0.000 0.580 0.420
E28.0 Oestrogen excess
0.000 0.580 0.420
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.581 0.419
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.583 0.417
K90 Intestinal malabsorption
0.000 0.584 0.416
I15.0 Renovascular hypertension
0.000 0.584 0.416
E25.9 Adrenogenital disorder, unspecified
0.000 0.585 0.415
E25.8 Other adrenogenital disorders
0.000 0.585 0.415
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.585 0.415
E30.9 Disorder of puberty, unspecified
0.000 0.585 0.415
E30.8 Other disorders of puberty
0.000 0.585 0.415
E30.1 Precocious puberty
0.000 0.585 0.415
E30.0 Delayed puberty
0.000 0.585 0.415
E31.9 Polyglandular dysfunction, unspecified
0.000 0.585 0.415
E31.8 Other polyglandular dysfunction
0.000 0.585 0.415
E31.1 Polyglandular hyperfunction
0.000 0.585 0.415
E31.0 Autoimmune polyglandular failure
0.000 0.585 0.415
E32.9 Disease of thymus, unspecified
0.000 0.585 0.415
E32.8 Other diseases of thymus
0.000 0.585 0.415
E32.1 Abscess of thymus
0.000 0.585 0.415
E32.0 Persistent hyperplasia of thymus
0.000 0.585 0.415
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.585 0.415
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.585 0.415
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.585 0.415
E88.9 Metabolic disorder, unspecified
0.000 0.586 0.414
E88.8 Other specified metabolic disorders
0.000 0.586 0.414
E88.3 Tumour lysis syndrome
0.000 0.586 0.414
I06 Rheumatic aortic valve diseases
0.000 0.586 0.414
I05.1 Rheumatic mitral insufficiency
0.000 0.589 0.411
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.590 0.410
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.590 0.410
E65-E68 Obesity and other hyperalimentation
0.000 0.591 0.409
I07 Rheumatic tricuspid valve diseases
0.000 0.593 0.407
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.594 0.406
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.595 0.405
I05.0 Mitral stenosis
0.000 0.600 0.400
I70.9 Generalised and unspecified atherosclerosis
0.000 0.600 0.400
I70.8 Atherosclerosis of other arteries
0.000 0.600 0.400
I08.0 Disorders of both mitral and aortic valves
0.000 0.600 0.400
E73.9 Lactose intolerance, unspecified
0.000 0.601 0.399
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.602 0.398
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.605 0.395
E29.9 Testicular dysfunction, unspecified
0.000 0.606 0.394
E29.8 Other testicular dysfunction
0.000 0.606 0.394
E29.0 Testicular hyperfunction
0.000 0.606 0.394
I12.0 Hypertensive renal disease with renal failure
0.000 0.607 0.393
E21.0 Primary hyperparathyroidism
0.000 0.610 0.390
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.614 0.386
E22.8 Other hyperfunction of pituitary gland
0.000 0.614 0.386
E88.2 Lipomatosis, not elsewhere classified
0.000 0.615 0.384
E26.9 Hyperaldosteronism, unspecified
0.000 0.619 0.380
E26.8 Other hyperaldosteronism
0.000 0.619 0.380
E26.1 Secondary hyperaldosteronism
0.000 0.619 0.380
G36.9 Acute disseminated demyelination, unspecified
0.378 0.621 0.000
G36.8 Other specified acute disseminated demyelination
0.378 0.621 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.378 0.621 0.000
G36.0 Neuromyelitis optica [Devic]
0.378 0.621 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.622 0.378
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.624 0.376
E20.8 Other hypoparathyroidism
0.000 0.625 0.375
E20.1 Pseudohypoparathyroidism
0.000 0.625 0.375
E20.0 Idiopathic hypoparathyroidism
0.000 0.625 0.375
L41.9 Parapsoriasis, unspecified
0.000 0.627 0.373
L41.8 Other parapsoriasis
0.000 0.627 0.373
L41.5 Retiform parapsoriasis
0.000 0.627 0.373
L41.4 Large plaque parapsoriasis
0.000 0.627 0.373
L41.3 Small plaque parapsoriasis
0.000 0.627 0.373
L41.2 Lymphomatoid papulosis
0.000 0.627 0.373
L41.1 Pityriasis lichenoides chronica
0.000 0.627 0.373
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.627 0.373
L44.9 Papulosquamous disorder, unspecified
0.000 0.627 0.373
L44.8 Other specified papulosquamous disorders
0.000 0.627 0.373
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.627 0.373
L44.3 Lichen ruber moniliformis
0.000 0.627 0.373
L44.2 Lichen striatus
0.000 0.627 0.373
L44.1 Lichen nitidus
0.000 0.627 0.373
L44.0 Pityriasis rubra pilaris
0.000 0.627 0.373
E22.1 Hyperprolactinaemia
0.000 0.630 0.370
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.630 0.369
E80.5 Crigler-Najjar syndrome
0.000 0.630 0.369
E80.3 Defects of catalase and peroxydase
0.000 0.630 0.369
E80.2 Other porphyria
0.000 0.630 0.369
E80.0 Hereditary erythropoietic porphyria
0.000 0.630 0.369
I05.8 Other mitral valve diseases
0.000 0.631 0.369
E29.1 Testicular hypofunction
0.000 0.634 0.366
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.636 0.364
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.636 0.364
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.636 0.364
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.636 0.364
E53 Deficiency of other B group vitamins
0.000 0.639 0.361
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.639 0.361
E46 Unspecified protein-energy malnutrition
0.000 0.639 0.361

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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