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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2534657
log Bayes Factor = 58.7859
Chromosome 6   position 31,472,459  (GRCh37) Explore rs2534657 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
L40.0 Psoriasis vulgaris
0.989 0.011 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.022 0.978
M35.3 Polymyalgia rheumatica
0.000 0.023 0.977
M35 Other systemic involvement of connective tissue
0.000 0.024 0.976
M06.9 Rheumatoid arthritis, unspecified
0.000 0.040 0.960
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.042 0.958
E06 Thyroiditis
0.000 0.044 0.956
E10-E14 Diabetes mellitus
0.000 0.057 0.943
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.060 0.940
E06.3 Autoimmune thyroiditis
0.000 0.081 0.919
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.082 0.918
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.109 0.891
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.116 0.884
E10.1 With ketoacidosis
0.000 0.124 0.876
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.137 0.863
G35 Multiple sclerosis
0.000 0.139 0.861
L40.1 Generalised pustular psoriasis
0.848 0.152 0.000
L40.8 Other psoriasis
0.822 0.178 0.000
M35.1 Other overlap syndromes
0.000 0.180 0.820
E10.2 With renal complications
0.000 0.221 0.779
E10.4 With neurological complications
0.000 0.224 0.776
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.772
E10.5 With peripheral circulatory complications
0.000 0.230 0.770
E03.8 Other specified hypothyroidism
0.000 0.233 0.767
M35.7 Hypermobility syndrome
0.000 0.253 0.747
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.253 0.747
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.269 0.731
E06.9 Thyroiditis, unspecified
0.000 0.281 0.719
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.300 0.700
M35.8 Other specified systemic involvement of connective tissue
0.000 0.300 0.700
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.300 0.700
M35.5 Multifocal fibrosclerosis
0.000 0.300 0.700
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.300 0.700
M35.2 Behcet's disease
0.000 0.300 0.700
E40-E46 Malnutrition
0.000 0.307 0.693
E06.5 Other chronic thyroiditis
0.000 0.315 0.685
E06.4 Drug-induced thyroiditis
0.000 0.315 0.685
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.315 0.685
E06.1 Subacute thyroiditis
0.000 0.315 0.685
E06.0 Acute thyroiditis
0.000 0.315 0.685
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.315 0.684
E12 Malnutrition-related diabetes mellitus
0.000 0.324 0.676
M06 Other rheumatoid arthritis
0.020 0.324 0.656
E05.8 Other thyrotoxicosis
0.000 0.338 0.662
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.344 0.656
E10.6 With other specified complications
0.000 0.357 0.642
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.360 0.640
E10.8 With unspecified complications
0.000 0.367 0.633
M06.0 Seronegative rheumatoid arthritis
0.009 0.383 0.608
E03.1 Congenital hypothyroidism without goitre
0.000 0.384 0.615
E65-E68 Obesity and other hyperalimentation
0.000 0.391 0.609
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.002 0.423 0.575
E07 Other disorders of thyroid
0.000 0.434 0.566
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.438 0.561
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.003 0.481 0.516
E46 Unspecified protein-energy malnutrition
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E65 Localised adiposity
0.000 0.487 0.513
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.498 0.502
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.503 0.497
E45 Retarded development following protein-energy malnutrition
0.000 0.503 0.497
E43 Unspecified severe protein-energy malnutrition
0.000 0.503 0.497
E42 Marasmic kwashiorkor
0.000 0.503 0.497
E41 Nutritional marasmus
0.000 0.503 0.497
E40 Kwashiorkor
0.000 0.503 0.497
E12.9 Without complications
0.000 0.515 0.485
E12.8 With unspecified complications
0.000 0.515 0.485
E12.7 With multiple complications
0.000 0.515 0.485
E12.6 With other specified complications
0.000 0.515 0.485
E12.5 With peripheral circulatory complications
0.000 0.515 0.485
E12.4 With neurological complications
0.000 0.515 0.485
E12.3 With ophthalmic complications
0.000 0.515 0.485
E12.2 With renal complications
0.000 0.515 0.485
E12.1 With ketoacidosis
0.000 0.515 0.485
E12.0 With coma
0.000 0.515 0.485
M06.8 Other specified rheumatoid arthritis
0.014 0.515 0.470
M06.2 Rheumatoid bursitis
0.014 0.515 0.470
M06.1 Adult-onset Still's disease
0.014 0.515 0.470
E13 Other specified diabetes mellitus
0.001 0.517 0.483
E50-E64 Other nutritional deficiencies
0.000 0.518 0.482
E14 Unspecified diabetes mellitus
0.000 0.532 0.468
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.538 0.461
M06.08 Seronegative rheumatoid arthritis (Other)
0.007 0.557 0.436
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.007 0.557 0.436
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.007 0.557 0.436
M06.04 Seronegative rheumatoid arthritis (Hand)
0.007 0.557 0.436
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.007 0.557 0.436
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.007 0.557 0.436
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.558 0.442
E67 Other hyperalimentation
0.000 0.563 0.437
E68 Sequelae of hyperalimentation
0.000 0.563 0.437
M06.3 Rheumatoid nodule
0.015 0.564 0.421
E07.1 Dyshormogenetic goitre
0.000 0.594 0.406
E07.0 Hypersecretion of calcitonin
0.000 0.594 0.406
E15 Nondiabetic hypoglycaemic coma
0.000 0.597 0.403
M06.4 Inflammatory polyarthropathy
0.016 0.611 0.372
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.007 0.616 0.377
L40-L45 Papulosquamous disorders
0.363 0.617 0.020
E53 Deficiency of other B group vitamins
0.000 0.631 0.369
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.007 0.632 0.361
E07.8 Other specified disorders of thyroid
0.000 0.640 0.359
E44.1 Mild protein-energy malnutrition
0.000 0.643 0.356
E44.0 Moderate protein-energy malnutrition
0.000 0.643 0.356
E14.3 With ophthalmic complications
0.000 0.649 0.351
M06.19 Adult-onset Still's disease (Site unspecified)
0.010 0.652 0.337
M06.18 Adult-onset Still's disease (Other)
0.010 0.652 0.337
M06.17 Adult-onset Still's disease (Ankle and foot)
0.010 0.652 0.337
M06.16 Adult-onset Still's disease (Lower leg)
0.010 0.652 0.337
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.010 0.652 0.337
M06.14 Adult-onset Still's disease (Hand)
0.010 0.652 0.337
M06.13 Adult-onset Still's disease (Forearm)
0.010 0.652 0.337
M06.12 Adult-onset Still's disease (Upper arm)
0.010 0.652 0.337
M06.11 Adult-onset Still's disease (Shoulder region)
0.010 0.652 0.337
M06.10 Adult-onset Still's disease (Multiple sites)
0.010 0.652 0.337
M06.29 Rheumatoid bursitis (Site unspecified)
0.010 0.652 0.337
M06.28 Rheumatoid bursitis (Other)
0.010 0.652 0.337
M06.27 Rheumatoid bursitis (Ankle and foot)
0.010 0.652 0.337
M06.26 Rheumatoid bursitis (Lower leg)
0.010 0.652 0.337
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.010 0.652 0.337
M06.24 Rheumatoid bursitis (Hand)
0.010 0.652 0.337
M06.23 Rheumatoid bursitis (Forearm)
0.010 0.652 0.337
M06.22 Rheumatoid bursitis (Upper arm)
0.010 0.652 0.337
M06.21 Rheumatoid bursitis (Shoulder region)
0.010 0.652 0.337
M06.20 Rheumatoid bursitis (Multiple sites)
0.010 0.652 0.337
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.010 0.652 0.337
M06.88 Other specified rheumatoid arthritis (Other)
0.010 0.652 0.337
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.010 0.652 0.337
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.010 0.652 0.337
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.010 0.652 0.337
M06.84 Other specified rheumatoid arthritis (Hand)
0.010 0.652 0.337
M06.83 Other specified rheumatoid arthritis (Forearm)
0.010 0.652 0.337
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.010 0.652 0.337
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.010 0.652 0.337
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.010 0.652 0.337
E13.8 With unspecified complications
0.001 0.653 0.346
E13.7 With multiple complications
0.001 0.653 0.346
E13.6 With other specified complications
0.001 0.653 0.346
E13.5 With peripheral circulatory complications
0.001 0.653 0.346
E13.4 With neurological complications
0.001 0.653 0.346
E13.3 With ophthalmic complications
0.001 0.653 0.346
E13.2 With renal complications
0.001 0.653 0.346
E13.1 With ketoacidosis
0.001 0.653 0.346
E13.0 With coma
0.001 0.653 0.346
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.654 0.345
E63 Other nutritional deficiencies
0.000 0.654 0.345
E56 Other vitamin deficiencies
0.000 0.654 0.345
E51 Thiamine deficiency
0.000 0.654 0.345
E50 Vitamin A deficiency
0.000 0.654 0.345
E60 Dietary zinc deficiency
0.000 0.654 0.345
E59 Dietary selenium deficiency
0.000 0.654 0.345
E58 Dietary calcium deficiency
0.000 0.654 0.345
E54 Ascorbic acid deficiency
0.000 0.654 0.345
E52 Niacin deficiency [pellagra]
0.000 0.654 0.345
G37 Other demyelinating diseases of central nervous system
0.000 0.656 0.344
E14.8 With unspecified complications
0.000 0.662 0.338
E14.7 With multiple complications
0.000 0.664 0.335
E14.6 With other specified complications
0.000 0.664 0.335
E14.5 With peripheral circulatory complications
0.000 0.664 0.335
E14.0 With coma
0.000 0.664 0.335
M06.34 Rheumatoid nodule (Hand)
0.008 0.665 0.326
E70-E90 Metabolic disorders
0.000 0.671 0.329
E07.9 Disorder of thyroid, unspecified
0.000 0.675 0.325
M07.39 Other psoriatic arthropathies (Site unspecified)
0.323 0.676 0.000
M07.3 Other psoriatic arthropathies
0.319 0.676 0.005
K90.0 Coeliac disease
0.000 0.677 0.323
E14.1 With ketoacidosis
0.000 0.680 0.320
G36 Other acute disseminated demyelination
0.000 0.683 0.317
E14.4 With neurological complications
0.000 0.684 0.315
E67.8 Other specified hyperalimentation
0.000 0.687 0.313
E67.3 Hypervitaminosis D
0.000 0.687 0.313
E67.2 Megavitamin-B6 syndrome
0.000 0.687 0.313
E67.1 Hypercarotenaemia
0.000 0.687 0.313
E67.0 Hypervitaminosis A
0.000 0.687 0.313
M06.39 Rheumatoid nodule (Site unspecified)
0.011 0.688 0.302
M06.38 Rheumatoid nodule (Other)
0.011 0.688 0.302
M06.36 Rheumatoid nodule (Lower leg)
0.011 0.688 0.302
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.011 0.688 0.302
M06.33 Rheumatoid nodule (Forearm)
0.011 0.688 0.302
M06.31 Rheumatoid nodule (Shoulder region)
0.011 0.688 0.302
M06.30 Rheumatoid nodule (Multiple sites)
0.011 0.688 0.302
M07.30 Other psoriatic arthropathies (Multiple sites)
0.309 0.690 0.001
M06.32 Rheumatoid nodule (Upper arm)
0.010 0.693 0.297
E14.2 Withrenal complications
0.000 0.701 0.299
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.703 0.297
L42 Pityriasis rosea
0.284 0.704 0.012
E04 Other non-toxic goitre
0.000 0.704 0.296
M05-M14 Inflammatory polyarthropathies
0.075 0.706 0.219
E20-E35 Disorders of other endocrine glands
0.000 0.708 0.292
E89.0 Postprocedural hypothyroidism
0.000 0.708 0.292
E53.8 Deficiency of other specified B group vitamins
0.000 0.709 0.291
E16 Other disorders of pancreatic internal secretion
0.000 0.710 0.290
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.714 0.286
M06.48 Inflammatory polyarthropathy (Other)
0.012 0.721 0.267
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.012 0.721 0.267
M06.46 Inflammatory polyarthropathy (Lower leg)
0.012 0.721 0.267
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.012 0.721 0.267
M06.44 Inflammatory polyarthropathy (Hand)
0.012 0.721 0.267
M06.43 Inflammatory polyarthropathy (Forearm)
0.012 0.721 0.267
M06.42 Inflammatory polyarthropathy (Upper arm)
0.012 0.721 0.267
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.012 0.721 0.267
E73 Lactose intolerance
0.000 0.722 0.278
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.011 0.724 0.265
L44 Other papulosquamous disorders
0.261 0.725 0.014
L41 Parapsoriasis
0.261 0.725 0.014
L45 Papulosquamous disorders in diseases classified elsewhere
0.261 0.725 0.014
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.271 0.727 0.003
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.728 0.272
M07 Psoriatic and enteropathic arthropathies
0.177 0.729 0.094
E80.4 Gilbert's syndrome
0.000 0.735 0.265
E53.1 Pyridoxine deficiency
0.000 0.735 0.265
E53.0 Riboflavin deficiency
0.000 0.735 0.265
M07.34 Other psoriatic arthropathies (Hand)
0.259 0.738 0.003
E53.9 Vitamin B deficiency, unspecified
0.000 0.739 0.261
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.750 0.250
E27 Other disorders of adrenal gland
0.000 0.751 0.249
E55 Vitamin D deficiency
0.000 0.751 0.249
E61 Deficiency of other nutrient elements
0.000 0.752 0.248
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.245 0.752 0.003
E50.9 Vitamin A deficiency, unspecified
0.000 0.752 0.248
E50.8 Other manifestations of vitamin A deficiency
0.000 0.752 0.248
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.752 0.248
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.752 0.248
E50.5 Vitamin A deficiency with night blindness
0.000 0.752 0.248
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.752 0.248
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.752 0.248
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.752 0.248
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.752 0.248
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.752 0.248
E51.9 Thiamine deficiency, unspecified
0.000 0.752 0.248
E51.8 Other manifestations of thiamine deficiency
0.000 0.752 0.248
E51.2 Wernicke's encephalopathy
0.000 0.752 0.248
E51.1 Beriberi
0.000 0.752 0.248
E56.9 Vitamin deficiency, unspecified
0.000 0.752 0.248
E56.8 Deficiency of other vitamins
0.000 0.752 0.248
E56.1 Deficiency of vitamin K
0.000 0.752 0.248
E56.0 Deficiency of vitamin E
0.000 0.752 0.248
E63.9 Nutritional deficiency, unspecified
0.000 0.752 0.248
E63.8 Other specified nutritional deficiencies
0.000 0.752 0.248
E63.1 Imbalance of constituents of food intake
0.000 0.752 0.248
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.752 0.248
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.752 0.248
E64.8 Sequelae of other nutritional deficiencies
0.000 0.752 0.248
E64.3 Sequelae of rickets
0.000 0.752 0.248
E64.2 Sequelae of vitamin C deficiency
0.000 0.752 0.248
E64.1 Sequelae of vitamin A deficiency
0.000 0.752 0.248
E64.0 Sequelae of protein-energy malnutrition
0.000 0.752 0.248
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.753 0.247
G37.5 Concentric sclerosis [Balo]
0.000 0.753 0.247
G37.4 Subacute necrotising myelitis
0.000 0.753 0.247
G37.2 Central pontine myelinolysis
0.000 0.753 0.247
G37.1 Central demyelination of corpus callosum
0.000 0.753 0.247
G37.0 Diffuse sclerosis
0.000 0.753 0.247
E73.9 Lactose intolerance, unspecified
0.000 0.759 0.241
E04.0 Non-toxic diffuse goitre
0.000 0.760 0.240
M05 Seropositive rheumatoid arthritis
0.043 0.760 0.197
E27.1 Primary adrenocortical insufficiency
0.000 0.761 0.239
E84 Cystic fibrosis
0.000 0.764 0.236
E79 Disorders of purine and pyrimidine metabolism
0.000 0.764 0.236
E77 Disorders of glycoprotein metabolism
0.000 0.764 0.236
E76 Disorders of glycosaminoglycan metabolism
0.000 0.764 0.236
E72 Other disorders of amino-acid metabolism
0.000 0.764 0.236
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.764 0.236
E70 Disorders of aromatic amino-acid metabolism
0.000 0.764 0.236
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.764 0.236
M07.38 Other psoriatic arthropathies (Other)
0.229 0.768 0.003
M07.33 Other psoriatic arthropathies (Forearm)
0.229 0.768 0.003
M07.32 Other psoriatic arthropathies (Upper arm)
0.229 0.768 0.003
M07.31 Other psoriatic arthropathies (Shoulder region)
0.229 0.768 0.003
M06.37 Rheumatoid nodule (Ankle and foot)
0.013 0.770 0.217
M07.36 Other psoriatic arthropathies (Lower leg)
0.226 0.771 0.003
E14.9 Without complications
0.000 0.771 0.229
G36.9 Acute disseminated demyelination, unspecified
0.000 0.772 0.227
G36.8 Other specified acute disseminated demyelination
0.000 0.772 0.227
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.772 0.227
G36.0 Neuromyelitis optica [Devic]
0.000 0.772 0.227
E83 Disorders of mineral metabolism
0.000 0.778 0.222
J47 Bronchiectasis
0.000 0.778 0.222
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.782 0.217
E20 Hypoparathyroidism
0.000 0.783 0.217
E74 Other disorders of carbohydrate metabolism
0.000 0.786 0.214
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.787 0.213
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.787 0.213
E89.5 Postprocedural testicular hypofunction
0.000 0.787 0.213
E89.4 Postprocedural ovarian failure
0.000 0.787 0.213
E89.1 Postprocedural hypoinsulinaemia
0.000 0.787 0.213
E04.8 Other specified non-toxic goitre
0.000 0.788 0.212
M12 Other specific arthropathies
0.054 0.789 0.157
M09 Juvenile arthritis in diseases classified elsewhere
0.054 0.789 0.157
M08 Juvenile arthritis
0.054 0.789 0.157
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.790 0.210
E32 Diseases of thymus
0.000 0.790 0.210
E31 Polyglandular dysfunction
0.000 0.790 0.210
E30 Disorders of puberty, not elsewhere classified
0.000 0.790 0.210
E25 Adrenogenital disorders
0.000 0.790 0.210
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.792 0.208
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.792 0.208
E16.4 Abnormal secretion of gastrin
0.000 0.792 0.208
E16.3 Increased secretion of glucagon
0.000 0.792 0.208
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.792 0.208
E28 Ovarian dysfunction
0.000 0.792 0.208
E26 Hyperaldosteronism
0.000 0.793 0.207
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.795 0.205
E80.6 Other disorders of bilirubin metabolism
0.000 0.795 0.205
E80.5 Crigler-Najjar syndrome
0.000 0.795 0.205
E80.3 Defects of catalase and peroxydase
0.000 0.795 0.205
E80.0 Hereditary erythropoietic porphyria
0.000 0.795 0.205
M05.9 Seropositive rheumatoid arthritis, unspecified
0.020 0.799 0.182
L43 Lichen planus
0.189 0.799 0.012
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.799 0.201
E29 Testicular dysfunction
0.000 0.800 0.199
E73.8 Other lactose intolerance
0.000 0.801 0.199
E73.1 Secondary lactase deficiency
0.000 0.801 0.199
E73.0 Congenital lactase deficiency
0.000 0.801 0.199
E89.3 Postprocedural hypopituitarism
0.000 0.802 0.198
L41.9 Parapsoriasis, unspecified
0.187 0.803 0.010
L41.8 Other parapsoriasis
0.187 0.803 0.010
L41.5 Retiform parapsoriasis
0.187 0.803 0.010
L41.4 Large plaque parapsoriasis
0.187 0.803 0.010
L41.3 Small plaque parapsoriasis
0.187 0.803 0.010
L41.2 Lymphomatoid papulosis
0.187 0.803 0.010
L41.1 Pityriasis lichenoides chronica
0.187 0.803 0.010
L41.0 Pityriasis lichenoides et varioliformis acuta
0.187 0.803 0.010
L44.9 Papulosquamous disorder, unspecified
0.187 0.803 0.010
L44.8 Other specified papulosquamous disorders
0.187 0.803 0.010
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.187 0.803 0.010
L44.3 Lichen ruber moniliformis
0.187 0.803 0.010
L44.2 Lichen striatus
0.187 0.803 0.010
L44.1 Lichen nitidus
0.187 0.803 0.010
L44.0 Pityriasis rubra pilaris
0.187 0.803 0.010
M07.6 Other enteropathic arthropathies
0.127 0.805 0.068
M07.5 Arthropathy in ulcerative colitis
0.127 0.805 0.068
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.127 0.805 0.068
M07.2 Psoriatic spondylitis
0.127 0.805 0.068
M07.1 Arthritis mutilans
0.127 0.805 0.068
M07.0 Distal interphalangeal psoriatic arthropathy
0.127 0.805 0.068
E83.3 Disorders of phosphorus metabolism
0.000 0.807 0.193
M10 Gout
0.034 0.807 0.159
K90 Intestinal malabsorption
0.000 0.811 0.189
M11 Other crystal arthropathies
0.051 0.811 0.138
E80.2 Other porphyria
0.000 0.811 0.188
M14 Arthropathies in other diseases classified elsewhere
0.062 0.812 0.126
E80.1 Porphyria cutanea tarda
0.000 0.813 0.187
E83.4 Disorders of magnesium metabolism
0.000 0.814 0.186
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.014 0.814 0.172
E27.2 Addisonian crisis
0.000 0.815 0.185
E66 Obesity
0.000 0.815 0.184
E22 Hyperfunction of pituitary gland
0.000 0.817 0.183
E27.5 Adrenomedullary hyperfunction
0.000 0.821 0.179
E27.0 Other adrenocortical overactivity
0.000 0.821 0.179
E55.0 Rickets, active
0.000 0.821 0.179
E61.9 Deficiency of nutrient element, unspecified
0.000 0.822 0.178
E61.8 Deficiency of other specified nutrient elements
0.000 0.822 0.178
E61.7 Deficiency of multiple nutrient elements
0.000 0.822 0.178
E61.6 Vanadium deficiency
0.000 0.822 0.178
E61.5 Molybdenum deficiency
0.000 0.822 0.178
E61.4 Chromium deficiency
0.000 0.822 0.178
E61.3 Manganese deficiency
0.000 0.822 0.178
E61.0 Copper deficiency
0.000 0.822 0.178
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.003 0.822 0.174
E86 Volume depletion
0.000 0.825 0.175
E24 Cushing's syndrome
0.000 0.827 0.173
M05.8 Other seropositive rheumatoid arthritis
0.031 0.828 0.141
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.031 0.828 0.141
M05.2 Rheumatoid vasculitis
0.031 0.828 0.141
M05.1 Rheumatoid lung disease
0.031 0.828 0.141
M05.0 Felty's syndrome
0.031 0.828 0.141
E85 Amyloidosis
0.000 0.829 0.170
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.831 0.169
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.831 0.169
E70.3 Albinism
0.000 0.831 0.169
E70.2 Disorders of tyrosine metabolism
0.000 0.831 0.169
E70.1 Other hyperphenylalaninaemias
0.000 0.831 0.169
E70.0 Classical phenylketonuria
0.000 0.831 0.169
E71.3 Disorders of fatty-acid metabolism
0.000 0.831 0.169
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.831 0.169
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.831 0.169
E71.0 Maple-syrup-urine disease
0.000 0.831 0.169
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.831 0.169
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.831 0.169
E72.5 Disorders of glycine metabolism
0.000 0.831 0.169
E72.4 Disorders of ornithine metabolism
0.000 0.831 0.169
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.831 0.169
E72.2 Disorders of urea cycle metabolism
0.000 0.831 0.169
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.831 0.169
E72.0 Disorders of amino-acid transport
0.000 0.831 0.169
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.831 0.169
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.831 0.169
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.831 0.169
E76.2 Other mucopolysaccharidoses
0.000 0.831 0.169
E76.1 Mucopolysaccharidosis, type II
0.000 0.831 0.169
E76.0 Mucopolysaccharidosis, type I
0.000 0.831 0.169
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.831 0.169
E77.8 Other disorders of glycoprotein metabolism
0.000 0.831 0.169
E77.1 Defects in glycoprotein degradation
0.000 0.831 0.169
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.831 0.169
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.831 0.169
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.831 0.169
E79.1 Lesch-Nyhan syndrome
0.000 0.831 0.169
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.831 0.169
E84.9 Cystic fibrosis, unspecified
0.000 0.831 0.169
E84.8 Cystic fibrosis with other manifestations
0.000 0.831 0.169
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.831 0.169
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.831 0.169
E27.8 Other specified disorders of adrenal gland
0.000 0.831 0.169
E88 Other metabolic disorders
0.000 0.833 0.167
E16.2 Hypoglycaemia, unspecified
0.000 0.833 0.167
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.064 0.833 0.104
K90.9 Intestinal malabsorption, unspecified
0.000 0.837 0.163
E20.9 Hypoparathyroidism, unspecified
0.000 0.837 0.163
E61.2 Magnesium deficiency
0.000 0.839 0.161
E16.1 Other hypoglycaemia
0.000 0.840 0.160
E23 Hypofunction and other disorders of pituitary gland
0.000 0.841 0.159
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.841 0.159
E83.8 Other disorders of mineral metabolism
0.000 0.841 0.159
E83.2 Disorders of zinc metabolism
0.000 0.841 0.159
E83.0 Disorders of copper metabolism
0.000 0.841 0.159
E34 Other endocrine disorders
0.000 0.841 0.159
E04.2 Non-toxic multinodular goitre
0.000 0.843 0.157
E75.6 Lipid storage disorder, unspecified
0.000 0.844 0.156
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.844 0.156
E75.3 Sphingolipidosis, unspecified
0.000 0.844 0.156
E75.2 Other sphingolipidosis
0.000 0.844 0.156
E75.1 Other gangliosidosis
0.000 0.844 0.156
E75.0 GM2 gangliosidosis
0.000 0.844 0.156
E20.8 Other hypoparathyroidism
0.000 0.844 0.156
E20.1 Pseudohypoparathyroidism
0.000 0.844 0.156
E20.0 Idiopathic hypoparathyroidism
0.000 0.844 0.156
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.844 0.156
T36-T50 Poisoning by drugs, medicaments and biological substances
0.155 0.845 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.846 0.154
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.846 0.154
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.846 0.154
E74.2 Disorders of galactose metabolism
0.000 0.846 0.154
E74.1 Disorders of fructose metabolism
0.000 0.846 0.154
E74.0 Glycogen storage disease
0.000 0.846 0.154
E13.9 Without complications
0.001 0.846 0.152
E27.9 Disorder of adrenal gland, unspecified
0.000 0.847 0.153
E28.3 Primary ovarian failure
0.000 0.847 0.153
M08.9 Juvenile arthritis, unspecified
0.039 0.848 0.113
M08.8 Other juvenile arthritis
0.039 0.848 0.113
M08.4 Pauciarticular juvenile arthritis
0.039 0.848 0.113
M08.3 Juvenile polyarthritis (seronegative)
0.039 0.848 0.113
M08.2 Juvenile arthritis with systemic onset
0.039 0.848 0.113
M08.1 Juvenile ankylosing spondylitis
0.039 0.848 0.113
M08.0 Juvenile rheumatoid arthritis
0.039 0.848 0.113
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.039 0.848 0.113
M09.2 Juvenile arthritis in ulcerative colitis
0.039 0.848 0.113
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.039 0.848 0.113
M09.0 Juvenile arthritis in psoriasis
0.039 0.848 0.113
M12.8 Other specific arthropathies, not elsewhere classified
0.039 0.848 0.113
M12.5 Traumatic arthropathy
0.039 0.848 0.113
M12.4 Intermittent hydrarthrosis
0.039 0.848 0.113
M12.3 Palindromic rheumatism
0.039 0.848 0.113
M12.2 Villonodular synovitis (pigmented)
0.039 0.848 0.113
M12.1 Kaschin-Beck disease
0.039 0.848 0.113
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.039 0.848 0.113
E25.9 Adrenogenital disorder, unspecified
0.000 0.849 0.150
E25.8 Other adrenogenital disorders
0.000 0.849 0.150
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.849 0.150
E30.9 Disorder of puberty, unspecified
0.000 0.849 0.150
E30.8 Other disorders of puberty
0.000 0.849 0.150
E30.1 Precocious puberty
0.000 0.849 0.150
E30.0 Delayed puberty
0.000 0.849 0.150
E31.9 Polyglandular dysfunction, unspecified
0.000 0.849 0.150
E31.8 Other polyglandular dysfunction
0.000 0.849 0.150

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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