TreeWAS – Variant ID: rs2535236

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.004	0.996
E10.9 Without complications	0.000	0.005	0.995
E10.4 With neurological complications	0.000	0.032	0.968
E10.3 With ophthalmic complications	0.000	0.038	0.962
E10.1 With ketoacidosis	0.000	0.050	0.950
E10.5 With peripheral circulatory complications	0.000	0.141	0.859
E10.6 With other specified complications	0.000	0.159	0.841
E10.2 With renal complications	0.000	0.202	0.797
E10.0 With coma	0.000	0.234	0.766
E10.7 With multiple complications	0.000	0.286	0.714
E10-E14 Diabetes mellitus	0.000	0.321	0.679
E10.8 With unspecified complications	0.000	0.327	0.673
E11 Non-insulin-dependent diabetes mellitus	0.000	0.364	0.636
E11.3 With ophthalmic complications	0.000	0.392	0.608
E11.2 With renal complications	0.000	0.411	0.589
E11.5 With peripheral circulatory complications	0.000	0.464	0.536
E11.1 With ketoacidosis	0.000	0.480	0.520
E12 Malnutrition-related diabetes mellitus	0.000	0.513	0.487
E13 Other specified diabetes mellitus	0.000	0.517	0.483
E11.7 With multiple complications	0.000	0.544	0.456
E11.8 With unspecified complications	0.000	0.551	0.449
E14 Unspecified diabetes mellitus	0.000	0.618	0.382
E11.0 With coma	0.000	0.619	0.381
E11.4 With neurological complications	0.000	0.630	0.370
K90 Intestinal malabsorption	0.000	0.646	0.354
E12.9 Without complications	0.000	0.651	0.349
E12.8 With unspecified complications	0.000	0.651	0.349
E12.7 With multiple complications	0.000	0.651	0.349
E12.6 With other specified complications	0.000	0.651	0.349
E12.5 With peripheral circulatory complications	0.000	0.651	0.349
E12.4 With neurological complications	0.000	0.651	0.349
E12.3 With ophthalmic complications	0.000	0.651	0.349
E12.2 With renal complications	0.000	0.651	0.349
E12.1 With ketoacidosis	0.000	0.651	0.349
E12.0 With coma	0.000	0.651	0.349
E13.8 With unspecified complications	0.000	0.653	0.346
E13.7 With multiple complications	0.000	0.653	0.346
E13.6 With other specified complications	0.000	0.653	0.346
E13.5 With peripheral circulatory complications	0.000	0.653	0.346
E13.4 With neurological complications	0.000	0.653	0.346
E13.3 With ophthalmic complications	0.000	0.653	0.346
E13.2 With renal complications	0.000	0.653	0.346
E13.1 With ketoacidosis	0.000	0.653	0.346
E13.0 With coma	0.000	0.653	0.346
E11.6 With other specified complications	0.000	0.655	0.345
E13.9 Without complications	0.000	0.657	0.343
E14.3 With ophthalmic complications	0.000	0.672	0.328
E14.5 With peripheral circulatory complications	0.000	0.694	0.306
E14.8 With unspecified complications	0.000	0.710	0.290
E14.1 With ketoacidosis	0.000	0.717	0.283
K90.8 Other intestinal malabsorption	0.000	0.725	0.275
E14.7 With multiple complications	0.000	0.726	0.274
E14.6 With other specified complications	0.000	0.726	0.274
E14.0 With coma	0.000	0.726	0.274
K90.3 Pancreatic steatorrhoea	0.000	0.746	0.254
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.746	0.254
K90.1 Tropical sprue	0.000	0.746	0.254
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.758	0.242
E14.2 Withrenal complications	0.000	0.772	0.227
E14.4 With neurological complications	0.000	0.793	0.207
K90.9 Intestinal malabsorption, unspecified	0.000	0.804	0.196
H36.0 Diabetic retinopathy	0.000	0.927	0.073
E83.1 Disorders of iron metabolism	0.000	0.942	0.058
E14.9 Without complications	0.000	0.945	0.055
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.955	0.045
H01.0 Blepharitis	0.000	0.958	0.042
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.958	0.042
E16 Other disorders of pancreatic internal secretion	0.000	0.960	0.040
E16.2 Hypoglycaemia, unspecified	0.000	0.961	0.039
H36 Retinal disorders in diseases classified elsewhere	0.000	0.967	0.033
E40-E46 Malnutrition	0.000	0.970	0.030
E15 Nondiabetic hypoglycaemic coma	0.000	0.970	0.030
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.970	0.030
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.971	0.029
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.971	0.029
E16.4 Abnormal secretion of gastrin	0.000	0.971	0.029
E16.3 Increased secretion of glucagon	0.000	0.971	0.029
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.972	0.028
E65-E68 Obesity and other hyperalimentation	0.000	0.973	0.027
E16.1 Other hypoglycaemia	0.000	0.974	0.026
R63.4 Abnormal weight loss	0.000	0.974	0.026
E83 Disorders of mineral metabolism	0.000	0.975	0.025
E00-E07 Disorders of thyroid gland	0.000	0.975	0.025
R63 Symptoms and signs concerning food and fluid intake	0.000	0.975	0.025
E70-E90 Metabolic disorders	0.000	0.975	0.025
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.976	0.024
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.976	0.024
E73 Lactose intolerance	0.000	0.977	0.023
E65 Localised adiposity	0.000	0.978	0.022
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.978	0.022
E45 Retarded development following protein-energy malnutrition	0.000	0.978	0.022
E43 Unspecified severe protein-energy malnutrition	0.000	0.978	0.022
E42 Marasmic kwashiorkor	0.000	0.978	0.022
E41 Nutritional marasmus	0.000	0.978	0.022
E40 Kwashiorkor	0.000	0.978	0.022
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.978	0.022
K90-K93 Other diseases of the digestive system	0.000	0.979	0.021
E05.9 Thyrotoxicosis, unspecified	0.000	0.979	0.021
E73.9 Lactose intolerance, unspecified	0.000	0.979	0.021
E07 Other disorders of thyroid	0.000	0.979	0.021
R63.1 Polydipsia	0.000	0.979	0.021
G25.0 Essential tremor	0.000	0.979	0.020
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.980	0.020
E07.8 Other specified disorders of thyroid	0.000	0.980	0.020
G25 Other extrapyramidal and movement disorders	0.000	0.980	0.020
E46 Unspecified protein-energy malnutrition	0.000	0.980	0.020
G25.3 Myoclonus	0.000	0.980	0.020
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.980	0.020
R63.6 Insufficient intake of food and water due to self neglect	0.000	0.981	0.019
E67 Other hyperalimentation	0.000	0.981	0.019
E68 Sequelae of hyperalimentation	0.000	0.981	0.019
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.981	0.019
R63.3 Feeding difficulties and mismanagement	0.000	0.981	0.018
E83.8 Other disorders of mineral metabolism	0.000	0.981	0.018
E83.2 Disorders of zinc metabolism	0.000	0.981	0.018
E83.0 Disorders of copper metabolism	0.000	0.981	0.018
E84 Cystic fibrosis	0.000	0.982	0.018
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.982	0.018
E89.0 Postprocedural hypothyroidism	0.000	0.982	0.018
H01 Other inflammation of eyelid	0.000	0.982	0.018
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.982	0.018
E00 Congenital iodine-deficiency syndrome	0.000	0.982	0.018
R63.2 Polyphagia	0.000	0.982	0.018
E77 Disorders of glycoprotein metabolism	0.000	0.982	0.018
E76 Disorders of glycosaminoglycan metabolism	0.000	0.982	0.018
E72 Other disorders of amino-acid metabolism	0.000	0.982	0.018
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.982	0.018
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.982	0.018
J40 Bronchitis, not specified as acute or chronic	0.017	0.983	0.000
E05.5 Thyroid crisis or storm	0.000	0.983	0.017
E05.4 Thyrotoxicosis factitia	0.000	0.983	0.017
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.983	0.017
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.983	0.017
E89.2 Postprocedural hypoparathyroidism	0.000	0.983	0.017
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.983	0.017
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.983	0.017
E85 Amyloidosis	0.000	0.983	0.017
E79 Disorders of purine and pyrimidine metabolism	0.000	0.983	0.017
E70 Disorders of aromatic amino-acid metabolism	0.000	0.983	0.016
E73.8 Other lactose intolerance	0.000	0.983	0.016
E73.1 Secondary lactase deficiency	0.000	0.983	0.016
E73.0 Congenital lactase deficiency	0.000	0.983	0.016
E88 Other metabolic disorders	0.000	0.984	0.016
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.984	0.016
E04 Other non-toxic goitre	0.000	0.984	0.016
E05.8 Other thyrotoxicosis	0.000	0.984	0.016
E44.1 Mild protein-energy malnutrition	0.000	0.984	0.016
E44.0 Moderate protein-energy malnutrition	0.000	0.984	0.016
E80.2 Other porphyria	0.000	0.984	0.016
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.984	0.016
E83.3 Disorders of phosphorus metabolism	0.000	0.985	0.015
R63.5 Abnormal weight gain	0.000	0.985	0.015
E07.1 Dyshormogenetic goitre	0.000	0.985	0.015
E07.0 Hypersecretion of calcitonin	0.000	0.985	0.015
E74 Other disorders of carbohydrate metabolism	0.000	0.985	0.015
E80.6 Other disorders of bilirubin metabolism	0.000	0.985	0.015
E85.4 Organ-limited amyloidosis	0.000	0.985	0.015
H01.9 Inflammation of eyelid, unspecified	0.000	0.985	0.015
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.985	0.015
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.985	0.015
E89.5 Postprocedural testicular hypofunction	0.000	0.985	0.015
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.985	0.015
G25.4 Drug-induced chorea	0.000	0.985	0.015
G25.2 Other specified forms of tremor	0.000	0.985	0.015
H01.1 Non-infectious dermatoses of eyelid	0.000	0.985	0.014
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.986	0.014
E80.5 Crigler-Najjar syndrome	0.000	0.986	0.014
E80.3 Defects of catalase and peroxydase	0.000	0.986	0.014
E80.0 Hereditary erythropoietic porphyria	0.000	0.986	0.014
E67.8 Other specified hyperalimentation	0.000	0.986	0.014
E67.3 Hypervitaminosis D	0.000	0.986	0.014
E67.2 Megavitamin-B6 syndrome	0.000	0.986	0.014
E67.1 Hypercarotenaemia	0.000	0.986	0.014
E67.0 Hypervitaminosis A	0.000	0.986	0.014
E80.1 Porphyria cutanea tarda	0.000	0.986	0.014
E84.9 Cystic fibrosis, unspecified	0.000	0.986	0.014
E89.4 Postprocedural ovarian failure	0.000	0.986	0.014
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.986	0.014
E04.1 Non-toxic single thyroid nodule	0.000	0.986	0.014
E84.8 Cystic fibrosis with other manifestations	0.000	0.986	0.013
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.986	0.013
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.986	0.013
G70.0 Myasthenia gravis	0.000	0.986	0.014
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.987	0.013
E80.4 Gilbert's syndrome	0.000	0.987	0.013
G25.5 Other chorea	0.000	0.987	0.013
E89.3 Postprocedural hypopituitarism	0.000	0.987	0.013
E89.1 Postprocedural hypoinsulinaemia	0.000	0.987	0.013
E04.0 Non-toxic diffuse goitre	0.000	0.987	0.013
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.987	0.013
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.987	0.013
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.987	0.013
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.987	0.013
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.987	0.013
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.987	0.013
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.987	0.013
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.987	0.013
E71.3 Disorders of fatty-acid metabolism	0.000	0.987	0.013
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.987	0.013
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.987	0.013
E71.0 Maple-syrup-urine disease	0.000	0.987	0.013
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.987	0.013
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.987	0.013
E72.5 Disorders of glycine metabolism	0.000	0.987	0.013
E72.4 Disorders of ornithine metabolism	0.000	0.987	0.013
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.987	0.013
E72.2 Disorders of urea cycle metabolism	0.000	0.987	0.013
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.987	0.013
E72.0 Disorders of amino-acid transport	0.000	0.987	0.013
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.987	0.013
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.987	0.013
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.987	0.013
E76.2 Other mucopolysaccharidoses	0.000	0.987	0.013
E76.1 Mucopolysaccharidosis, type II	0.000	0.987	0.013
E76.0 Mucopolysaccharidosis, type I	0.000	0.987	0.013
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.987	0.013
E77.8 Other disorders of glycoprotein metabolism	0.000	0.987	0.013
E77.1 Defects in glycoprotein degradation	0.000	0.987	0.013
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.987	0.013
G25.1 Drug-induced tremor	0.000	0.987	0.013
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.987	0.013
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.987	0.013
E75.6 Lipid storage disorder, unspecified	0.000	0.987	0.012
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.987	0.012
E75.3 Sphingolipidosis, unspecified	0.000	0.987	0.012
E75.2 Other sphingolipidosis	0.000	0.987	0.012
E75.1 Other gangliosidosis	0.000	0.987	0.012
E75.0 GM2 gangliosidosis	0.000	0.987	0.012
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.988	0.012
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.988	0.012
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.988	0.012
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.988	0.012
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.988	0.012
E79.1 Lesch-Nyhan syndrome	0.000	0.988	0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.988	0.012
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.988	0.012
E70.2 Disorders of tyrosine metabolism	0.000	0.988	0.012
E70.1 Other hyperphenylalaninaemias	0.000	0.988	0.012
E70.0 Classical phenylketonuria	0.000	0.988	0.012
E04.8 Other specified non-toxic goitre	0.000	0.988	0.012
E85.8 Other amyloidosis	0.000	0.988	0.012
E75.5 Other lipid storage disorders	0.000	0.988	0.012
E11.9 Without complications	0.000	0.988	0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.988	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.988	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.988	0.011
E85.3 Secondary systemic amyloidosis	0.000	0.989	0.011
E88.2 Lipomatosis, not elsewhere classified	0.000	0.989	0.011
E04.2 Non-toxic multinodular goitre	0.000	0.989	0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.989	0.011
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.989	0.011
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.989	0.011
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.989	0.011
E74.2 Disorders of galactose metabolism	0.000	0.989	0.011
E74.1 Disorders of fructose metabolism	0.000	0.989	0.011
E88.3 Tumour lysis syndrome	0.000	0.989	0.011
E70.3 Albinism	0.000	0.989	0.010
E74.0 Glycogen storage disease	0.000	0.989	0.010
E50-E64 Other nutritional deficiencies	0.000	0.989	0.010
E88.9 Metabolic disorder, unspecified	0.000	0.990	0.010
L03.1 Cellulitis of other parts of limb	0.000	0.990	0.010
E88.8 Other specified metabolic disorders	0.000	0.990	0.010
G35 Multiple sclerosis	0.000	0.990	0.010
R63.0 Anorexia	0.000	0.990	0.010
G70 Myasthenia gravis and other myoneural disorders	0.000	0.990	0.010
E85.9 Amyloidosis, unspecified	0.000	0.990	0.009
J31.0 Chronic rhinitis	0.009	0.991	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.991	0.009
H01.8 Other specified inflammation of eyelid	0.000	0.991	0.009
E07.9 Disorder of thyroid, unspecified	0.000	0.991	0.009
G70.9 Myoneural disorder, unspecified	0.000	0.992	0.008
E51 Thiamine deficiency	0.000	0.992	0.008
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.992	0.008
E63 Other nutritional deficiencies	0.000	0.992	0.008
E50 Vitamin A deficiency	0.000	0.992	0.008
E60 Dietary zinc deficiency	0.000	0.992	0.008
E59 Dietary selenium deficiency	0.000	0.992	0.008
E54 Ascorbic acid deficiency	0.000	0.992	0.008
E52 Niacin deficiency [pellagra]	0.000	0.992	0.008
E06 Thyroiditis	0.000	0.992	0.007
E56 Other vitamin deficiencies	0.000	0.992	0.007
J42 Unspecified chronic bronchitis	0.008	0.992	0.000
G70.8 Other specified myoneural disorders	0.000	0.993	0.007
G70.2 Congenital and developmental myasthenia	0.000	0.993	0.007
G70.1 Toxic myoneural disorders	0.000	0.993	0.007
K81.0 Acute cholecystitis	0.007	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.993	0.007
J46 Status asthmaticus	0.007	0.993	0.000
C18.2 Ascending colon	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.993	0.007
E58 Dietary calcium deficiency	0.000	0.993	0.006
E83.4 Disorders of magnesium metabolism	0.000	0.993	0.007
S61.0 Open wound of finger(s) without damage to nail	0.007	0.993	0.000
J40-J47 Chronic lower respiratory diseases	0.006	0.994	0.000
E51.2 Wernicke's encephalopathy	0.000	0.994	0.006
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.994	0.006
E51.9 Thiamine deficiency, unspecified	0.000	0.994	0.006
E51.8 Other manifestations of thiamine deficiency	0.000	0.994	0.006
E51.1 Beriberi	0.000	0.994	0.006
G70-G73 Diseases of myoneural junction and muscle	0.000	0.994	0.006
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.006
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.006
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.006
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.006
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.006
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.006
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.006
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.006
E63.9 Nutritional deficiency, unspecified	0.000	0.994	0.006
E63.8 Other specified nutritional deficiencies	0.000	0.994	0.006
E63.1 Imbalance of constituents of food intake	0.000	0.994	0.006
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.994	0.006
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.006
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.006
E64.3 Sequelae of rickets	0.000	0.994	0.006
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.006
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.006
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.006
E25 Adrenogenital disorders	0.000	0.994	0.006
E24.2 Drug-induced Cushing's syndrome	0.000	0.994	0.006
E66 Obesity	0.000	0.994	0.006
E06.4 Drug-induced thyroiditis	0.000	0.994	0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.994	0.005
E06.0 Acute thyroiditis	0.000	0.994	0.005
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.005
E56.8 Deficiency of other vitamins	0.000	0.994	0.005
E56.0 Deficiency of vitamin E	0.000	0.994	0.005
K86.8 Other specified diseases of pancreas	0.000	0.994	0.006
E53 Deficiency of other B group vitamins	0.000	0.994	0.006
E03 Other hypothyroidism	0.000	0.994	0.006
E24.9 Cushing's syndrome, unspecified	0.000	0.994	0.006
E24.0 Pituitary-dependent Cushing's disease	0.000	0.994	0.006
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.994	0.006
S82.30 Fracture of lower end of tibia (closed)	0.000	0.994	0.006
E28 Ovarian dysfunction	0.000	0.994	0.005
E20 Hypoparathyroidism	0.000	0.994	0.005
G37 Other demyelinating diseases of central nervous system	0.000	0.994	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.000	0.995	0.005
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.005
E56.1 Deficiency of vitamin K	0.000	0.995	0.005
E06.5 Other chronic thyroiditis	0.000	0.995	0.005
E55 Vitamin D deficiency	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
C67.2 Lateral wall of bladder	0.005	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.005
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.005
E24.1 Nelson's syndrome	0.000	0.995	0.005
G71 Primary disorders of muscles	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
G71.0 Muscular dystrophy	0.000	0.995	0.005
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.995	0.005
J41 Simple and mucopurulent chronic bronchitis	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
K81.1 Chronic cholecystitis	0.005	0.995	0.000
E28.3 Primary ovarian failure	0.000	0.995	0.005
E29 Testicular dysfunction	0.000	0.995	0.005
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.005	0.995	0.000
K81 Cholecystitis	0.005	0.995	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.005	0.995	0.000
E06.1 Subacute thyroiditis	0.001	0.995	0.004
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.995	0.004
G72 Other myopathies	0.000	0.995	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004
C16.0 Cardia	0.004	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.996	0.004
M75.0 Adhesive capsulitis of shoulder	0.004	0.996	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.000	0.996	0.004
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
E03.5 Myxoedema coma	0.000	0.996	0.004
E03.4 Atrophy of thyroid (acquired)	0.000	0.996	0.004
E03.3 Postinfectious hypothyroidism	0.000	0.996	0.004
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.996	0.004
G36 Other acute disseminated demyelination	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
E28.9 Ovarian dysfunction, unspecified	0.000	0.996	0.004
E28.8 Other ovarian dysfunction	0.000	0.996	0.004
E28.1 Androgen excess	0.000	0.996	0.004
E28.0 Oestrogen excess	0.000	0.996	0.004
J11.1 Influenza with other respiratory manifestations, virus not identified	0.004	0.996	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.996	0.004
G37.4 Subacute necrotising myelitis	0.000	0.996	0.004
G37.2 Central pontine myelinolysis	0.000	0.996	0.004
G37.1 Central demyelination of corpus callosum	0.000	0.996	0.004
G37.0 Diffuse sclerosis	0.000	0.996	0.004
K75.4 Autoimmune hepatitis	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.004
E30.8 Other disorders of puberty	0.000	0.996	0.004
E30.1 Precocious puberty	0.000	0.996	0.004
E30.0 Delayed puberty	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.004
E31.8 Other polyglandular dysfunction	0.000	0.996	0.004
E31.1 Polyglandular hyperfunction	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.004
E32.9 Disease of thymus, unspecified	0.000	0.996	0.004
E32.8 Other diseases of thymus	0.000	0.996	0.004
E32.1 Abscess of thymus	0.000	0.996	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.004
E34.8 Other specified endocrine disorders	0.000	0.996	0.004
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.004	0.996	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.004	0.996	0.000
E55.0 Rickets, active	0.000	0.996	0.004
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.996	0.004
E34.5 Androgen resistance syndrome	0.000	0.996	0.004
E34.4 Constitutional tall stature	0.000	0.996	0.004
E34.3 Short stature, not elsewhere classified	0.000	0.996	0.004
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.004
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.001	0.996	0.003
N87.1 Moderate cervical dysplasia	0.004	0.996	0.000
E26 Hyperaldosteronism	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.000	0.996	0.004
E04.9 Non-toxic goitre, unspecified	0.000	0.996	0.004
E06.3 Autoimmune thyroiditis	0.000	0.996	0.004
G71.9 Primary disorder of muscle, unspecified	0.000	0.996	0.004
G71.8 Other primary disorders of muscles	0.000	0.996	0.004
G71.2 Congenital myopathies	0.000	0.996	0.004
E66.8 Other obesity	0.000	0.996	0.004
K81.9 Cholecystitis, unspecified	0.004	0.996	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.996	0.004
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.996	0.004
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.996	0.004
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.004	0.996	0.000
J41.1 Mucopurulent chronic bronchitis	0.004	0.996	0.000
J41.0 Simple chronic bronchitis	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
E61.9 Deficiency of nutrient element, unspecified	0.000	0.996	0.003
E61.8 Deficiency of other specified nutrient elements	0.000	0.996	0.003
E61.7 Deficiency of multiple nutrient elements	0.000	0.996	0.003
E61.6 Vanadium deficiency	0.000	0.996	0.003
E61.5 Molybdenum deficiency	0.000	0.996	0.003
E61.4 Chromium deficiency	0.000	0.996	0.003
E61.3 Manganese deficiency	0.000	0.996	0.003
E61.0 Copper deficiency	0.000	0.996	0.003
H30-H36 Disorders of choroid and retina	0.000	0.996	0.004
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.003
E29.8 Other testicular dysfunction	0.000	0.996	0.003
E29.0 Testicular hyperfunction	0.000	0.996	0.003
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.003
G72.0 Drug-induced myopathy	0.000	0.996	0.004
E22.1 Hyperprolactinaemia	0.000	0.996	0.004
E28.2 Polycystic ovarian syndrome	0.000	0.996	0.004
E03.1 Congenital hypothyroidism without goitre	0.000	0.996	0.003
E53.9 Vitamin B deficiency, unspecified	0.000	0.996	0.003
E03.8 Other specified hypothyroidism	0.000	0.996	0.003
G73.7 Myopathy other diseases classified elsewhere	0.000	0.996	0.003
G73.6 Myopathy in metabolic diseases	0.000	0.996	0.003
G73.5 Myopathy in endocrine diseases	0.000	0.996	0.003
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.996	0.003
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.996	0.003
G73.1 Eaton-Lambert syndrome	0.000	0.996	0.003
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.996	0.003
G72.3 Periodic paralysis	0.000	0.996	0.003
G72.2 Myopathy due to other toxic agents	0.000	0.996	0.003
G72.1 Alcoholic myopathy	0.000	0.996	0.003
E83.5 Disorders of calcium metabolism	0.000	0.997	0.003
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.997	0.003
G72.8 Other specified myopathies	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
G36.9 Acute disseminated demyelination, unspecified	0.000	0.997	0.003
G36.8 Other specified acute disseminated demyelination	0.000	0.997	0.003
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.997	0.003
G20-G26 Extrapyramidal and movement disorders	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.997	0.003
L03.0 Cellulitis of finger and toe	0.000	0.997	0.003
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.997	0.003
L91.8 Other hypertrophic disorders of skin	0.000	0.997	0.003
M20.3 Other deformity of hallux (acquired)	0.000	0.997	0.003
H34.2 Other retinal artery occlusions	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.000	0.997	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.003
E78.2 Mixed hyperlipidaemia	0.000	0.997	0.003
M75.1 Rotator cuff syndrome	0.003	0.997	0.000
G71.1 Myotonic disorders	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations