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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2535290
log Bayes Factor = 139.413
Chromosome 6   position 31,063,132  (GRCh37) Explore rs2535290 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.999 0.001 0.000
E07 Other disorders of thyroid
0.000 0.002 0.998
E07.9 Disorder of thyroid, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
L40.5 Arthropathic psoriasis
0.989 0.011 0.000
L40.0 Psoriasis vulgaris
0.985 0.015 0.000
E83.1 Disorders of iron metabolism
0.963 0.037 0.000
C61 Malignant neoplasm of prostate
0.902 0.098 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.152 0.848
L40.4 Guttate psoriasis
0.818 0.182 0.000
E03.8 Other specified hypothyroidism
0.000 0.198 0.802
L40.3 Pustulosis palmaris et plantaris
0.791 0.209 0.000
K90 Intestinal malabsorption
0.000 0.212 0.788
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.242 0.758
E06 Thyroiditis
0.000 0.245 0.755
L40.1 Generalised pustular psoriasis
0.738 0.262 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E07.1 Dyshormogenetic goitre
0.000 0.284 0.716
E07.0 Hypersecretion of calcitonin
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.299 0.701
E07.8 Other specified disorders of thyroid
0.000 0.300 0.700
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.305 0.695
E05.8 Other thyrotoxicosis
0.000 0.307 0.693
E10.9 Without complications
0.000 0.311 0.689
E10 Insulin-dependent diabetes mellitus
0.000 0.323 0.677
K90.9 Intestinal malabsorption, unspecified
0.000 0.345 0.655
E10-E14 Diabetes mellitus
0.000 0.346 0.654
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.347 0.653
E10.3 With ophthalmic complications
0.000 0.349 0.651
L40.8 Other psoriasis
0.648 0.351 0.000
E06.3 Autoimmune thyroiditis
0.000 0.373 0.627
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.394 0.606
E06.5 Other chronic thyroiditis
0.000 0.394 0.606
E03.1 Congenital hypothyroidism without goitre
0.000 0.398 0.602
K90.8 Other intestinal malabsorption
0.000 0.408 0.592
E10.2 With renal complications
0.000 0.420 0.580
K90.3 Pancreatic steatorrhoea
0.000 0.435 0.565
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.435 0.565
K90.1 Tropical sprue
0.000 0.435 0.565
E06.4 Drug-induced thyroiditis
0.000 0.458 0.542
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.458 0.542
E06.0 Acute thyroiditis
0.000 0.458 0.542
E06.1 Subacute thyroiditis
0.000 0.473 0.527
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M35.0 Sicca syndrome [Sjogren]
0.000 0.499 0.501
E20-E35 Disorders of other endocrine glands
0.000 0.509 0.491
E10.7 With multiple complications
0.000 0.512 0.488
E14 Unspecified diabetes mellitus
0.000 0.513 0.487
E10.4 With neurological complications
0.000 0.518 0.482
E10.0 With coma
0.000 0.526 0.473
E28 Ovarian dysfunction
0.000 0.528 0.472
E12 Malnutrition-related diabetes mellitus
0.000 0.531 0.469
E28.3 Primary ovarian failure
0.000 0.554 0.446
E14.3 With ophthalmic complications
0.000 0.560 0.440
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.574 0.426
E23 Hypofunction and other disorders of pituitary gland
0.000 0.574 0.426
E40-E46 Malnutrition
0.000 0.576 0.424
E24 Cushing's syndrome
0.000 0.587 0.413
E10.8 With unspecified complications
0.000 0.589 0.410
E13 Other specified diabetes mellitus
0.000 0.597 0.403
E10.6 With other specified complications
0.000 0.599 0.400
E28.2 Polycystic ovarian syndrome
0.000 0.600 0.400
E23.2 Diabetes insipidus
0.000 0.607 0.393
E14.5 With peripheral circulatory complications
0.000 0.614 0.386
E10.1 With ketoacidosis
0.000 0.626 0.374
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.630 0.370
E24.2 Drug-induced Cushing's syndrome
0.000 0.633 0.367
E06.9 Thyroiditis, unspecified
0.000 0.635 0.365
E14.1 With ketoacidosis
0.000 0.643 0.357
E14.8 With unspecified complications
0.000 0.644 0.356
E31 Polyglandular dysfunction
0.000 0.645 0.355
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.648 0.352
E32 Diseases of thymus
0.000 0.648 0.352
E30 Disorders of puberty, not elsewhere classified
0.000 0.648 0.352
E14.7 With multiple complications
0.000 0.651 0.349
E14.0 With coma
0.000 0.651 0.349
E14.6 With other specified complications
0.000 0.656 0.344
E10.5 With peripheral circulatory complications
0.000 0.658 0.342
E28.9 Ovarian dysfunction, unspecified
0.000 0.662 0.338
E28.8 Other ovarian dysfunction
0.000 0.662 0.338
E28.1 Androgen excess
0.000 0.662 0.338
E28.0 Oestrogen excess
0.000 0.662 0.338
E12.9 Without complications
0.000 0.663 0.336
E12.8 With unspecified complications
0.000 0.663 0.336
E12.7 With multiple complications
0.000 0.663 0.336
E12.6 With other specified complications
0.000 0.663 0.336
E12.5 With peripheral circulatory complications
0.000 0.663 0.336
E12.4 With neurological complications
0.000 0.663 0.336
E12.3 With ophthalmic complications
0.000 0.663 0.336
E12.2 With renal complications
0.000 0.663 0.336
E12.1 With ketoacidosis
0.000 0.663 0.336
E12.0 With coma
0.000 0.663 0.336
E14.2 Withrenal complications
0.000 0.666 0.334
E21.3 Hyperparathyroidism, unspecified
0.000 0.667 0.333
E23.7 Disorder of pituitary gland, unspecified
0.000 0.669 0.331
E23.6 Other disorders of pituitary gland
0.000 0.669 0.331
E14.4 With neurological complications
0.000 0.678 0.322
E13.3 With ophthalmic complications
0.000 0.686 0.314
E26 Hyperaldosteronism
0.000 0.686 0.313
C60-C63 Malignant neoplasms of male genital organs
0.313 0.687 0.000
E20 Hypoparathyroidism
0.000 0.688 0.312
E25 Adrenogenital disorders
0.000 0.694 0.306
E15 Nondiabetic hypoglycaemic coma
0.000 0.694 0.306
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.695 0.305
E23.1 Drug-induced hypopituitarism
0.000 0.695 0.305
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.696 0.304
E45 Retarded development following protein-energy malnutrition
0.000 0.696 0.304
E43 Unspecified severe protein-energy malnutrition
0.000 0.696 0.304
E42 Marasmic kwashiorkor
0.000 0.696 0.304
E41 Nutritional marasmus
0.000 0.696 0.304
E40 Kwashiorkor
0.000 0.696 0.304
E24.0 Pituitary-dependent Cushing's disease
0.000 0.697 0.303
E50-E64 Other nutritional deficiencies
0.000 0.702 0.298
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.703 0.296
E24.3 Ectopic ACTH syndrome
0.000 0.703 0.296
E24.1 Nelson's syndrome
0.000 0.703 0.296
E24.8 Other Cushing's syndrome
0.000 0.710 0.290
E13.8 With unspecified complications
0.000 0.711 0.289
E13.7 With multiple complications
0.000 0.711 0.289
E13.6 With other specified complications
0.000 0.711 0.289
E13.5 With peripheral circulatory complications
0.000 0.711 0.289
E13.4 With neurological complications
0.000 0.711 0.289
E13.2 With renal complications
0.000 0.711 0.289
E13.1 With ketoacidosis
0.000 0.711 0.289
E13.0 With coma
0.000 0.711 0.289
E29 Testicular dysfunction
0.000 0.720 0.280
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.726 0.274
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.726 0.274
E24.9 Cushing's syndrome, unspecified
0.000 0.729 0.271
E21.2 Other hyperparathyroidism
0.000 0.733 0.267
E16 Other disorders of pancreatic internal secretion
0.000 0.737 0.263
E46 Unspecified protein-energy malnutrition
0.000 0.740 0.260
E31.0 Autoimmune polyglandular failure
0.000 0.743 0.257
E31.9 Polyglandular dysfunction, unspecified
0.000 0.745 0.254
E31.8 Other polyglandular dysfunction
0.000 0.745 0.254
E31.1 Polyglandular hyperfunction
0.000 0.745 0.254
L40-L45 Papulosquamous disorders
0.254 0.746 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.747 0.252
E30.8 Other disorders of puberty
0.000 0.747 0.252
E30.1 Precocious puberty
0.000 0.747 0.252
E30.0 Delayed puberty
0.000 0.747 0.252
E32.9 Disease of thymus, unspecified
0.000 0.747 0.252
E32.8 Other diseases of thymus
0.000 0.747 0.252
E32.1 Abscess of thymus
0.000 0.747 0.252
E32.0 Persistent hyperplasia of thymus
0.000 0.747 0.252
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.747 0.252
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.747 0.252
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.747 0.252
E21.4 Other specified disorders of parathyroid gland
0.000 0.753 0.247
C60 Malignant neoplasm of penis
0.244 0.755 0.000
E22 Hyperfunction of pituitary gland
0.000 0.759 0.241
E34 Other endocrine disorders
0.001 0.761 0.239
H00.1 Chalazion
0.238 0.762 0.000
C83.3 Large cell (diffuse)
0.000 0.767 0.233
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.771 0.229
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.774 0.226
E51 Thiamine deficiency
0.000 0.774 0.225
E26.9 Hyperaldosteronism, unspecified
0.000 0.775 0.225
E26.8 Other hyperaldosteronism
0.000 0.775 0.225
E26.1 Secondary hyperaldosteronism
0.000 0.775 0.225
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.775 0.225
E20.8 Other hypoparathyroidism
0.000 0.776 0.224
E20.1 Pseudohypoparathyroidism
0.000 0.776 0.224
E20.0 Idiopathic hypoparathyroidism
0.000 0.776 0.224
E58 Dietary calcium deficiency
0.000 0.778 0.222
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.779 0.221
E56 Other vitamin deficiencies
0.000 0.780 0.220
E25.9 Adrenogenital disorder, unspecified
0.000 0.780 0.220
E25.8 Other adrenogenital disorders
0.000 0.780 0.220
E44.1 Mild protein-energy malnutrition
0.000 0.782 0.218
E44.0 Moderate protein-energy malnutrition
0.000 0.782 0.218
C85.1 B-cell lymphoma, unspecified
0.000 0.782 0.218
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.782 0.218
C63 Malignant neoplasm of other and unspecified male genital organs
0.217 0.783 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.786 0.214
E63 Other nutritional deficiencies
0.000 0.786 0.214
E50 Vitamin A deficiency
0.000 0.786 0.214
E60 Dietary zinc deficiency
0.000 0.786 0.214
E59 Dietary selenium deficiency
0.000 0.786 0.214
E52 Niacin deficiency [pellagra]
0.000 0.786 0.214
C81 Hodgkin's disease
0.000 0.788 0.212
M35 Other systemic involvement of connective tissue
0.000 0.792 0.208
E61 Deficiency of other nutrient elements
0.000 0.794 0.206
E65-E68 Obesity and other hyperalimentation
0.000 0.794 0.205
L41 Parapsoriasis
0.203 0.797 0.000
E29.8 Other testicular dysfunction
0.000 0.799 0.201
E29.0 Testicular hyperfunction
0.000 0.799 0.201
C81.9 Hodgkin's disease, unspecified
0.000 0.802 0.198
E29.9 Testicular dysfunction, unspecified
0.000 0.803 0.197
E34.8 Other specified endocrine disorders
0.000 0.805 0.194
C60.9 Penis, unspecified
0.191 0.809 0.000
E54 Ascorbic acid deficiency
0.000 0.810 0.190
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.811 0.189
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.811 0.189
E16.4 Abnormal secretion of gastrin
0.000 0.811 0.189
E16.3 Increased secretion of glucagon
0.000 0.811 0.189
C60.1 Glans penis
0.187 0.813 0.000
E26.0 Primary hyperaldosteronism
0.000 0.814 0.186
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.815 0.185
E20.9 Hypoparathyroidism, unspecified
0.000 0.815 0.184
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.816 0.184
L45 Papulosquamous disorders in diseases classified elsewhere
0.182 0.818 0.000
L44 Other papulosquamous disorders
0.182 0.818 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.819 0.180
C81.2 Mixed cellularity
0.000 0.821 0.179
C83.7 Burkitt's tumour
0.000 0.821 0.179
C60.8 Overlapping lesion of penis
0.175 0.824 0.000
C60.2 Body of penis
0.175 0.824 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.826 0.174
E13.9 Without complications
0.000 0.826 0.174
E51.2 Wernicke's encephalopathy
0.000 0.826 0.174
M35.7 Hypermobility syndrome
0.000 0.827 0.173
E22.8 Other hyperfunction of pituitary gland
0.000 0.827 0.173
C81.1 Nodular sclerosis
0.000 0.827 0.173
C62 Malignant neoplasm of testis
0.172 0.827 0.000
E34.5 Androgen resistance syndrome
0.001 0.828 0.171
E34.4 Constitutional tall stature
0.001 0.828 0.171
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.828 0.171
E34.1 Other hypersecretion of intestinal hormones
0.001 0.828 0.171
E16.1 Other hypoglycaemia
0.000 0.828 0.171
C60.0 Prepuce
0.167 0.833 0.000
C81.0 Lymphocytic predominance
0.000 0.833 0.167
L41.1 Pityriasis lichenoides chronica
0.166 0.834 0.000
E56.1 Deficiency of vitamin K
0.000 0.835 0.165
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.836 0.164
C83.1 Small cleaved cell (diffuse)
0.000 0.836 0.164
C85.0 Lymphosarcoma
0.000 0.838 0.162
L42 Pityriasis rosea
0.162 0.838 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.838 0.162
E51.9 Thiamine deficiency, unspecified
0.000 0.838 0.162
E51.8 Other manifestations of thiamine deficiency
0.000 0.838 0.162
E51.1 Beriberi
0.000 0.838 0.162
E61.2 Magnesium deficiency
0.000 0.839 0.161
M35.1 Other overlap syndromes
0.000 0.840 0.160
M35.8 Other specified systemic involvement of connective tissue
0.000 0.841 0.159
C83.6 Undifferentiated (diffuse)
0.000 0.841 0.159
C83.4 Immunoblastic (diffuse)
0.000 0.841 0.159
C83.2 Mixed small and large cell (diffuse)
0.000 0.841 0.159
E56.9 Vitamin deficiency, unspecified
0.000 0.842 0.158
E56.8 Deficiency of other vitamins
0.000 0.842 0.158
E56.0 Deficiency of vitamin E
0.000 0.842 0.158
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.842 0.157
C86 Other specified types of T/NK-cell lymphoma
0.000 0.843 0.157
M35.2 Behcet's disease
0.000 0.843 0.157
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.843 0.156
C63.9 Male genital organ, unspecified
0.155 0.844 0.000
C63.8 Overlapping lesion of male genital organs
0.155 0.844 0.000
C63.7 Other specified male genital organs
0.155 0.844 0.000
C63.1 Spermatic cord
0.155 0.844 0.000
C63.0 Epididymis
0.155 0.844 0.000
E53 Deficiency of other B group vitamins
0.000 0.846 0.154
E27 Other disorders of adrenal gland
0.000 0.846 0.154
E50.9 Vitamin A deficiency, unspecified
0.000 0.847 0.153
E50.8 Other manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.847 0.153
E50.5 Vitamin A deficiency with night blindness
0.000 0.847 0.153
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.847 0.153
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.847 0.153
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.847 0.153
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.847 0.153
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.847 0.153
E63.9 Nutritional deficiency, unspecified
0.000 0.847 0.153
E63.8 Other specified nutritional deficiencies
0.000 0.847 0.153
E63.1 Imbalance of constituents of food intake
0.000 0.847 0.153
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.847 0.153
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.847 0.153
E64.8 Sequelae of other nutritional deficiencies
0.000 0.847 0.153
E64.3 Sequelae of rickets
0.000 0.847 0.153
E64.2 Sequelae of vitamin C deficiency
0.000 0.847 0.153
E64.1 Sequelae of vitamin A deficiency
0.000 0.847 0.153
E64.0 Sequelae of protein-energy malnutrition
0.000 0.847 0.153
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.847 0.153
C92 Myeloid leukaemia
0.000 0.847 0.153
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.848 0.152
C81.3 Lymphocytic depletion
0.000 0.848 0.152
E23.0 Hypopituitarism
0.000 0.848 0.152
C95 Leukaemia of unspecified cell type
0.000 0.848 0.151
C93 Monocytic leukaemia
0.000 0.849 0.150
C83.5 Lymphoblastic (diffuse)
0.000 0.850 0.149
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.851 0.149
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.851 0.149
M35.5 Multifocal fibrosclerosis
0.000 0.851 0.149
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.851 0.149
C88 Malignant immunoproliferative diseases
0.000 0.851 0.149
E61.9 Deficiency of nutrient element, unspecified
0.000 0.852 0.148
E61.8 Deficiency of other specified nutrient elements
0.000 0.852 0.148
E61.7 Deficiency of multiple nutrient elements
0.000 0.852 0.148
E61.6 Vanadium deficiency
0.000 0.852 0.148
E61.5 Molybdenum deficiency
0.000 0.852 0.148
E61.4 Chromium deficiency
0.000 0.852 0.148
E61.3 Manganese deficiency
0.000 0.852 0.148
E61.0 Copper deficiency
0.000 0.852 0.148
C92.1 Chronic myeloid leukaemia
0.000 0.852 0.148
C63.2 Scrotum
0.147 0.852 0.000
E67 Other hyperalimentation
0.000 0.852 0.147
E68 Sequelae of hyperalimentation
0.000 0.852 0.147
E22.1 Hyperprolactinaemia
0.000 0.854 0.146
L41.9 Parapsoriasis, unspecified
0.146 0.854 0.000
L41.8 Other parapsoriasis
0.146 0.854 0.000
L41.5 Retiform parapsoriasis
0.146 0.854 0.000
L41.4 Large plaque parapsoriasis
0.146 0.854 0.000
L41.3 Small plaque parapsoriasis
0.146 0.854 0.000
L41.2 Lymphomatoid papulosis
0.146 0.854 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.146 0.854 0.000
E55 Vitamin D deficiency
0.000 0.854 0.146
C94 Other leukaemias of specified cell type
0.000 0.854 0.146
H00 Hordeolum and chalazion
0.142 0.858 0.000
C81.7 Other Hodgkin's disease
0.000 0.859 0.141
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.859 0.141
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.860 0.140
C82.3 Follicular lymphoma grade IIIa
0.000 0.863 0.137
E29.1 Testicular hypofunction
0.000 0.864 0.136
L44.9 Papulosquamous disorder, unspecified
0.130 0.869 0.000
L44.8 Other specified papulosquamous disorders
0.130 0.869 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.130 0.869 0.000
L44.3 Lichen ruber moniliformis
0.130 0.869 0.000
L44.2 Lichen striatus
0.130 0.869 0.000
L44.1 Lichen nitidus
0.130 0.869 0.000
L44.0 Pityriasis rubra pilaris
0.130 0.870 0.000
C84.0 Mycosis fungoides
0.000 0.876 0.124
C62.0 Undescended testis
0.124 0.876 0.000
C82.2 Large cell, follicular
0.000 0.877 0.123
H00.0 Hordeolum and other deep inflammation of eyelid
0.122 0.878 0.000
E61.1 Iron deficiency
0.000 0.878 0.122
C62.1 Descended testis
0.121 0.879 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.879 0.121
C95.9 Leukaemia, unspecified
0.000 0.880 0.120
E21.0 Primary hyperparathyroidism
0.000 0.881 0.119
C82.6 Cutaneous follicle centre lymphoma
0.000 0.882 0.118
C82.5 Diffuse follicle centre lymphoma
0.000 0.882 0.118
K60.2 Anal fissure, unspecified
0.000 0.884 0.116
C84.5 Other and unspecified T-cell lymphomas
0.000 0.884 0.116
E27.1 Primary adrenocortical insufficiency
0.000 0.887 0.113
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.887 0.113
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.887 0.113
C86.4 Blastic NK-cell lymphoma
0.000 0.887 0.113
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.887 0.113
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.887 0.113
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.887 0.113
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.887 0.113
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.887 0.112
C96.8 Histiocytic sarcoma
0.000 0.887 0.112
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.887 0.112
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.887 0.112
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.887 0.112
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.887 0.112
C96.3 True histiocytic lymphoma
0.000 0.887 0.112
C96.2 Malignant mast cell tumour
0.000 0.887 0.112
C96.1 Malignant histiocytosis
0.000 0.887 0.112
C96.0 Letterer-Siwe disease
0.000 0.887 0.112
E53.1 Pyridoxine deficiency
0.000 0.889 0.111
E53.0 Riboflavin deficiency
0.000 0.889 0.111
E65 Localised adiposity
0.000 0.889 0.111
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.889 0.110
E27.5 Adrenomedullary hyperfunction
0.000 0.889 0.110
E27.0 Other adrenocortical overactivity
0.000 0.889 0.110
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.890 0.110
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.890 0.110
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.890 0.110
C84.3 Lymphoepithelioid lymphoma
0.000 0.890 0.110
C84.2 T-zone lymphoma
0.000 0.890 0.110
C84.1 Sezary's diease
0.000 0.890 0.110
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.890 0.109
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.890 0.109
C92.3 Myeloid sarcoma
0.000 0.890 0.109
C92.2 Subacute myeloid leukaemia
0.000 0.890 0.109
C95.7 Other leukaemia of unspecified cell type
0.000 0.891 0.109
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.891 0.109
E27.9 Disorder of adrenal gland, unspecified
0.000 0.892 0.108
C93.9 Monocytic leukaemia, unspecified
0.000 0.892 0.108
C93.7 Other monocytic leukaemia
0.000 0.892 0.108
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.892 0.108
C93.2 Subacute monocytic leukaemia
0.000 0.892 0.108
C93.0 Acute monocytic leukaemia
0.000 0.892 0.108
K60 Fissure and fistula of anal and rectal regions
0.000 0.892 0.108
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.893 0.107
C92.5 Acute myelomonocytic leukaemia
0.000 0.893 0.107
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.893 0.107
C88.7 Other malignant immunoproliferative diseases
0.000 0.893 0.107
C88.3 Immunoproliferative small intestinal disease
0.000 0.893 0.107
C88.2 Gamma heavy chain disease
0.000 0.893 0.107
C88.1 Alpha heavy chain disease
0.000 0.893 0.107
E53.9 Vitamin B deficiency, unspecified
0.000 0.893 0.107
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.894 0.106
E67.8 Other specified hyperalimentation
0.000 0.894 0.106
E67.3 Hypervitaminosis D
0.000 0.894 0.106
E67.2 Megavitamin-B6 syndrome
0.000 0.894 0.106
E67.1 Hypercarotenaemia
0.000 0.894 0.106
E67.0 Hypervitaminosis A
0.000 0.894 0.106
E22.0 Acromegaly and pituitary gigantism
0.000 0.894 0.105
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.895 0.105
E55.0 Rickets, active
0.000 0.895 0.105
C94.7 Other specified leukaemias
0.000 0.895 0.104
C94.5 Acute myelofibrosis
0.000 0.895 0.104
C94.4 Acute panmyelosis
0.000 0.895 0.104
C94.3 Mast cell leukaemia
0.000 0.895 0.104
C94.2 Acute megakaryoblastic leukaemia
0.000 0.895 0.104
C94.1 Chronic erythraemia
0.000 0.895 0.104
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.895 0.104
C82.4 Follicular lymphoma grade IIIb
0.000 0.896 0.104
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.896 0.104
C82.0 Small cleaved cell, follicular
0.000 0.897 0.103
C93.1 Chronic monocytic leukaemia
0.000 0.898 0.102
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.898 0.102
K60.0 Acute anal fissure
0.000 0.899 0.101
K60.3 Anal fistula
0.000 0.899 0.101
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.902 0.098
C92.9 Myeloid leukaemia, unspecified
0.000 0.903 0.096
E34.9 Endocrine disorder, unspecified
0.001 0.905 0.094
E14.9 Without complications
0.000 0.906 0.094
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.906 0.093
K60.5 Anorectal fistula
0.000 0.907 0.092
C95.0 Acute leukaemia of unspecified cell type
0.000 0.908 0.091
E34.0 Carcinoid syndrome
0.001 0.909 0.090
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.910 0.090
L43 Lichen planus
0.087 0.913 0.000
C84.4 Peripheral T-cell lymphoma
0.000 0.913 0.086
C91 Lymphoid leukaemia
0.000 0.913 0.086
C92.4 Acute promyelocytic leukaemia
0.000 0.915 0.085
K60.4 Rectal fistula
0.000 0.915 0.085
C92.7 Other myeloid leukaemia
0.000 0.918 0.082
E27.2 Addisonian crisis
0.000 0.922 0.078
C62.9 Testis, unspecified
0.077 0.923 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.924 0.076
C83.0 Small cell (diffuse)
0.000 0.926 0.074
C91.9 Lymphoid leukaemia, unspecified
0.000 0.927 0.073
L43.3 Subacute (active) lichen planus
0.062 0.937 0.000
L43.2 Lichenoid drug reaction
0.062 0.937 0.000
L43.1 Bullous lichen planus
0.062 0.937 0.000
L43.0 Hypertrophic lichen planus
0.062 0.937 0.000
E04 Other non-toxic goitre
0.000 0.937 0.062
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.938 0.062
C91.7 Other lymphoid leukaemia
0.000 0.938 0.062
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.938 0.062
C91.3 Prolymphocytic leukaemia
0.000 0.938 0.062
C91.2 Subacute lymphocytic leukaemia
0.000 0.938 0.062
C91.5 Adult T-cell leukaemia
0.000 0.938 0.062
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.939 0.060
E53.8 Deficiency of other specified B group vitamins
0.000 0.940 0.060
E27.8 Other specified disorders of adrenal gland
0.000 0.941 0.058
E16.2 Hypoglycaemia, unspecified
0.000 0.942 0.058
C91.4 Hairy-cell leukaemia
0.000 0.947 0.052
L43.8 Other lichen planus
0.050 0.949 0.001
C92.0 Acute myeloid leukaemia
0.000 0.950 0.050
K90-K93 Other diseases of the digestive system
0.000 0.951 0.049
C90.1 Plasma cell leukaemia
0.001 0.953 0.046
C91.0 Acute lymphoblastic leukaemia
0.000 0.955 0.045
E04.8 Other specified non-toxic goitre
0.000 0.955 0.045
E83 Disorders of mineral metabolism
0.040 0.955 0.004
C90.3 Solitary plasmacytoma
0.001 0.958 0.041
M35.3 Polymyalgia rheumatica
0.000 0.959 0.041
K50.0 Crohn's disease of small intestine
0.040 0.960 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.962 0.038
E55.9 Vitamin D deficiency, unspecified
0.000 0.963 0.037
Z51.3 Blood transfusion without reported diagnosis
0.000 0.963 0.037
N05.2 Diffuse membranous glomerulonephritis
0.000 0.964 0.036
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.965 0.035
N05.9 Unspecified
0.000 0.965 0.035
N05 Unspecified nephritic syndrome
0.000 0.965 0.035
E83.9 Disorder of mineral metabolism, unspecified
0.030 0.967 0.003
K60.1 Chronic anal fissure
0.000 0.967 0.033
E83.8 Other disorders of mineral metabolism
0.029 0.968 0.003
E83.2 Disorders of zinc metabolism
0.029 0.968 0.003
E83.0 Disorders of copper metabolism
0.029 0.968 0.003
K50 Crohn's disease [regional enteritis]
0.031 0.969 0.000
K50.8 Other Crohn's disease
0.031 0.969 0.000
N05.1 Focal and segmental glomerular lesions
0.000 0.970 0.030
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.971 0.029
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.027 0.973 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.974 0.025
K93.1 Megacolon in Chagas' disease
0.000 0.974 0.025
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.974 0.025
K50.1 Crohn's disease of large intestine
0.025 0.975 0.000
N05.6 Dense deposit disease
0.000 0.975 0.025
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.975 0.025
N05.0 Minor glomerular abnormality
0.000 0.975 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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