TreeWAS – Variant ID: rs2535296

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	0.999	0.001	0.000
D64 Other anaemias	0.999	0.001	0.000
E14 Unspecified diabetes mellitus	0.999	0.001	0.000
D64.9 Anaemia, unspecified	0.999	0.001	0.000
N00-N08 Glomerular diseases	0.998	0.002	0.000
E27 Other disorders of adrenal gland	0.998	0.002	0.000
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
J40-J47 Chronic lower respiratory diseases	0.997	0.003	0.000
Chapter XIV Diseases of the genitourinary system	0.997	0.003	0.000
Chapter X Diseases of the respiratory system	0.997	0.003	0.000
M20.1 Hallux valgus (acquired)	0.000	0.004	0.996
D86 Sarcoidosis	0.995	0.005	0.000
B35-B49 Mycoses	0.995	0.005	0.000
I73 Other peripheral vascular diseases	0.995	0.005	0.000
N17-N19 Renal failure	0.995	0.005	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.994	0.006	0.000
J45 Asthma	0.994	0.006	0.000
E10.1 With ketoacidosis	0.993	0.007	0.000
E14.3 With ophthalmic complications	0.993	0.007	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.993	0.007	0.000
J45.9 Asthma, unspecified	0.993	0.007	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.993	0.007	0.000
J44 Other chronic obstructive pulmonary disease	0.993	0.007	0.000
B37 Candidiasis	0.991	0.009	0.000
N05 Unspecified nephritic syndrome	0.991	0.009	0.000
M20 Acquired deformities of fingers and toes	0.000	0.010	0.990
N18 Chronic renal failure	0.990	0.010	0.000
I60-I69 Cerebrovascular diseases	0.990	0.010	0.000
E70-E90 Metabolic disorders	0.989	0.011	0.000
I63 Cerebral infarction	0.989	0.011	0.000
N40 Hyperplasia of prostate	0.000	0.012	0.988
E10.2 With renal complications	0.987	0.013	0.000
C85.1 B-cell lymphoma, unspecified	0.986	0.014	0.000
D61 Other aplastic anaemias	0.986	0.014	0.000
E11 Non-insulin-dependent diabetes mellitus	0.986	0.014	0.000
D86.9 Sarcoidosis, unspecified	0.985	0.015	0.000
D50-D53 Nutritional anaemias	0.984	0.016	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.984	0.016	0.000
I73.0 Raynaud's syndrome	0.983	0.017	0.000
B37.9 Candidiasis, unspecified	0.982	0.018	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.018	0.982
N40-N51 Diseases of male genital organs	0.000	0.018	0.982
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.980	0.020	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.979	0.021	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.978	0.022	0.000
H34 Retinal vascular occlusions	0.976	0.024	0.000
E89.0 Postprocedural hypothyroidism	0.975	0.025	0.000
K70-K77 Diseases of liver	0.975	0.025	0.000
D61.9 Aplastic anaemia, unspecified	0.973	0.027	0.000
Chapter XX External causes of morbidity and mortality	0.972	0.028	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.972	0.028	0.000
Chapter XI Diseases of the digestive system	0.969	0.029	0.002
K75 Other inflammatory liver diseases	0.970	0.030	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.969	0.031	0.000
N04 Nephrotic syndrome	0.969	0.031	0.000
K75.4 Autoimmune hepatitis	0.968	0.032	0.000
M15-M19 Arthrosis	0.967	0.033	0.000
D69 Purpura and other haemorrhagic conditions	0.967	0.033	0.000
D50 Iron deficiency anaemia	0.967	0.033	0.000
B02 Zoster [herpes zoster]	0.965	0.035	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.960	0.040	0.000
M18 Arthrosis of first carpometacarpal joint	0.960	0.040	0.000
Chapter VI Diseases of the nervous system	0.958	0.042	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.957	0.043	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.955	0.045	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.955	0.045	0.000
D50.8 Other iron deficiency anaemias	0.954	0.046	0.000
N18.9 Chronic renal failure, unspecified	0.954	0.046	0.000
D80 Immunodeficiency with predominantly antibody defects	0.953	0.047	0.000
C83.3 Large cell (diffuse)	0.951	0.049	0.000
E06 Thyroiditis	0.950	0.050	0.000
I74 Arterial embolism and thrombosis	0.950	0.050	0.000
E11.3 With ophthalmic complications	0.949	0.051	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.947	0.053	0.000
N42 Other disorders of prostate	0.000	0.054	0.946
W00-W19 Falls	0.945	0.055	0.000
D69.6 Thrombocytopenia, unspecified	0.945	0.055	0.000
N48 Other disorders of penis	0.000	0.055	0.945
I73.9 Peripheral vascular disease, unspecified	0.944	0.056	0.000
N41 Inflammatory diseases of prostate	0.000	0.057	0.943
G51 Facial nerve disorders	0.942	0.058	0.000
I77 Other disorders of arteries and arterioles	0.942	0.058	0.000
K50-K52 Noninfective enteritis and colitis	0.935	0.059	0.006
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.941	0.059	0.000
N05.2 Diffuse membranous glomerulonephritis	0.940	0.060	0.000
B02.9 Zoster without complication	0.940	0.060	0.000
H34.8 Other retinal vascular occlusions	0.940	0.060	0.000
M60-M63 Disorders of muscles	0.938	0.062	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.936	0.063	0.000
K52 Other non-infective gastro-enteritis and colitis	0.934	0.064	0.003
I63.8 Other cerebral infarction	0.933	0.067	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.068	0.932
W19 Unspecified fall	0.932	0.068	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.928	0.072	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.928	0.072	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.072	0.928
J46 Status asthmaticus	0.926	0.074	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.926	0.074	0.000
G56 Mononeuropathies of upper limb	0.924	0.076	0.000
K73 Chronic hepatitis, not elsewhere classified	0.924	0.076	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.924	0.076	0.000
G56.0 Carpal tunnel syndrome	0.922	0.078	0.000
K72 Hepatic failure, not elsewhere classified	0.921	0.079	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.920	0.080	0.000
G30-G32 Other degenerative diseases of the nervous system	0.919	0.081	0.000
E50-E64 Other nutritional deficiencies	0.918	0.082	0.000
N04.9 Unspecified	0.918	0.082	0.000
N48.4 Impotence of organic origin	0.000	0.082	0.918
M24 Other specific joint derangements	0.915	0.085	0.000
G51.0 Bell's palsy	0.914	0.086	0.000
M21 Other acquired deformities of limbs	0.914	0.086	0.000
B37.0 Candidal stomatitis	0.914	0.086	0.000
B15-B19 Viral hepatitis	0.913	0.087	0.000
E10.4 With neurological complications	0.912	0.088	0.000
I71 Aortic aneurysm and dissection	0.908	0.092	0.000
E06.3 Autoimmune thyroiditis	0.908	0.092	0.000
K74 Fibrosis and cirrhosis of liver	0.905	0.095	0.000
I77.1 Stricture of artery	0.905	0.095	0.000
E78.5 Hyperlipidaemia, unspecified	0.903	0.097	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.903	0.097	0.000
N05.9 Unspecified	0.903	0.097	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.901	0.099	0.000
D86.0 Sarcoidosis of lung	0.901	0.099	0.000
N18.3 Chronic kidney disease, stage 3	0.899	0.101	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.898	0.102	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.898	0.102	0.000
J84 Other interstitial pulmonary diseases	0.897	0.103	0.000
E24 Cushing's syndrome	0.894	0.106	0.000
N42.8 Other specified disorders of prostate	0.000	0.106	0.894
K75.8 Other specified inflammatory liver diseases	0.892	0.108	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.891	0.109	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.109	0.890
J33 Nasal polyp	0.890	0.110	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.111	0.889
E23 Hypofunction and other disorders of pituitary gland	0.886	0.114	0.000
J33.0 Polyp of nasal cavity	0.885	0.115	0.000
J30-J39 Other diseases of upper respiratory tract	0.885	0.115	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.885	0.115	0.000
K40 Inguinal hernia	0.002	0.116	0.882
A50-A64 Infections with a predominantly sexual mode of transmission	0.883	0.117	0.000
B25-B34 Other viral diseases	0.882	0.118	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.118	0.882
Y42.0 Glucocorticoids and synthetic analogs	0.881	0.119	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.881	0.119	0.000
B37.8 Candidiasis of other sites	0.881	0.119	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.880	0.120	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.880	0.120	0.000
M62 Other disorders of muscle	0.877	0.123	0.000
Y42.7 Androgens and anabolic congeners	0.876	0.124	0.000
E88 Other metabolic disorders	0.875	0.125	0.000
H34.2 Other retinal artery occlusions	0.874	0.126	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.873	0.127	0.000
I27 Other pulmonary heart diseases	0.871	0.129	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.870	0.130	0.000
K72.0 Acute and subacute hepatic failure	0.868	0.132	0.000
E14.8 With unspecified complications	0.868	0.132	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.866	0.134	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.866	0.134	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.864	0.136	0.000
E11.1 With ketoacidosis	0.863	0.137	0.000
N18.0 End-stage renal disease	0.863	0.137	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.863	0.137	0.000
I77.6 Arteritis, unspecified	0.863	0.137	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.862	0.138	0.000
E11.9 Without complications	0.862	0.138	0.000
G51.9 Disorder of facial nerve, unspecified	0.862	0.138	0.000
M15 Polyarthrosis	0.859	0.141	0.000
H06.2 Dysthyroid exophthalmos	0.858	0.142	0.000
H05 Disorders of orbit	0.853	0.147	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.852	0.148	0.000
J33.9 Nasal polyp, unspecified	0.852	0.148	0.000
M21.0 Valgus deformity, not elsewhere classified	0.850	0.150	0.000
D69.4 Other primary thrombocytopenia	0.849	0.151	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.848	0.152	0.000
I27.2 Other secondary pulmonary hypertension	0.846	0.154	0.000
Y52 Agents primarily affecting the cardiovascular system	0.845	0.155	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.844	0.156	0.000
C88 Malignant immunoproliferative diseases	0.843	0.156	0.000
M32 Systemic lupus erythematosus	0.843	0.157	0.000
J95-J99 Other diseases of the respiratory system	0.843	0.157	0.000
C83.0 Small cell (diffuse)	0.842	0.158	0.000
M34 Systemic sclerosis	0.842	0.158	0.000
G31.8 Other specified degenerative diseases of nervous system	0.842	0.158	0.000
B25 Cytomegaloviral disease	0.841	0.159	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.839	0.161	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.839	0.161	0.000
B44 Aspergillosis	0.838	0.162	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.837	0.163	0.000
N48.1 Balanoposthitis	0.000	0.164	0.836
B18 Chronic viral hepatitis	0.835	0.165	0.000
E14.2 Withrenal complications	0.834	0.166	0.000
V40-V49 Car occupant injured in transport accident	0.834	0.166	0.000
H30 Chorioretinal inflammation	0.833	0.167	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.833	0.167	0.000
M21.8 Other specified acquired deformities of limbs	0.831	0.169	0.000
M33 Dermatopolymyositis	0.830	0.170	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.830	0.170	0.000
D51 Vitamin B12 deficiency anaemia	0.830	0.170	0.000
Q50-Q56 Congenital malformations of genital organs	0.830	0.170	0.000
M62.8 Other specified disorders of muscle	0.828	0.172	0.000
E13 Other specified diabetes mellitus	0.828	0.172	0.000
K90-K93 Other diseases of the digestive system	0.826	0.173	0.001
W19.2 School, other institution and public administrative area	0.826	0.174	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.825	0.175	0.000
N19 Unspecified renal failure	0.825	0.175	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.825	0.175	0.000
K74.6 Other and unspecified cirrhosis of liver	0.824	0.176	0.000
W19.4 Street and highway	0.823	0.177	0.000
N17 Acute renal failure	0.822	0.178	0.000
J37 Chronic laryngitis and laryngotracheitis	0.821	0.179	0.000
W05 Fall involving wheelchair	0.821	0.179	0.000
N04.2 Diffuse membranous glomerulonephritis	0.820	0.180	0.000
E73 Lactose intolerance	0.819	0.181	0.000
D83 Common variable immunodeficiency	0.819	0.181	0.000
E23.6 Other disorders of pituitary gland	0.819	0.181	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.819	0.181	0.000
E10.0 With coma	0.818	0.182	0.000
E14.9 Without complications	0.818	0.182	0.000
K90 Intestinal malabsorption	0.817	0.183	0.000
W13 Fall from, out of or through building or structure	0.817	0.183	0.000
E10.8 With unspecified complications	0.816	0.184	0.000
E07 Other disorders of thyroid	0.815	0.185	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.813	0.187	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.812	0.188	0.000
E10.7 With multiple complications	0.808	0.192	0.000
I74.8 Embolism and thrombosis of other arteries	0.808	0.192	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.808	0.192	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.808	0.192	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.807	0.192	0.000
B37.7 Candidal septicaemia	0.806	0.194	0.000
C81 Hodgkin's disease	0.804	0.196	0.000
B25.9 Cytomegaloviral disease, unspecified	0.804	0.196	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.804	0.196	0.000
E14.6 With other specified complications	0.803	0.197	0.000
W19.9 Unspecified place	0.802	0.198	0.000
D69.2 Other nonthrombocytopenic purpura	0.799	0.201	0.000
E31 Polyglandular dysfunction	0.799	0.201	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.201	0.799
A30-A49 Other bacterial diseases	0.799	0.201	0.000
K73.9 Chronic hepatitis, unspecified	0.798	0.202	0.000
J45.1 Nonallergic asthma	0.797	0.203	0.000
D64.8 Other specified anaemias	0.797	0.203	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.797	0.203	0.000
C92 Myeloid leukaemia	0.797	0.203	0.000
B02.2 Zoster with other nervous system involvement	0.795	0.205	0.000
E53 Deficiency of other B group vitamins	0.794	0.206	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.794	0.206	0.000
N18.2 Chronic kidney disease, stage 2	0.793	0.207	0.000
H04 Disorders of lachrymal system	0.793	0.207	0.000
K74.3 Primary biliary cirrhosis	0.793	0.207	0.000
I63.9 Cerebral infarction, unspecified	0.791	0.209	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.791	0.209	0.000
C83.1 Small cleaved cell (diffuse)	0.790	0.210	0.000
E11.2 With renal complications	0.790	0.210	0.000
M00-M03 Infectious arthropathies	0.789	0.211	0.000
H00.1 Chalazion	0.000	0.211	0.789
N41.1 Chronic prostatitis	0.000	0.212	0.788
N05.1 Focal and segmental glomerular lesions	0.787	0.213	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.213	0.787
E27.4 Other and unspecified adrenocortical insufficiency	0.786	0.214	0.000
H31 Other disorders of choroid	0.785	0.215	0.000
E14.1 With ketoacidosis	0.785	0.215	0.000
E24.2 Drug-induced Cushing's syndrome	0.785	0.215	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.784	0.216	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.783	0.217	0.000
K90.9 Intestinal malabsorption, unspecified	0.781	0.219	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.780	0.220	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.780	0.220	0.000
D50.1 Sideropenic dysphagia	0.779	0.221	0.000
Q60-Q64 Congenital malformations of the urinary system	0.777	0.223	0.000
H05.2 Exophthalmic conditions	0.777	0.223	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.777	0.223	0.000
M35.7 Hypermobility syndrome	0.776	0.223	0.000
B18.2 Chronic viral hepatitis C	0.776	0.224	0.000
J37.0 Chronic laryngitis	0.776	0.224	0.000
E11.0 With coma	0.776	0.224	0.000
M24.5 Contracture of joint	0.774	0.226	0.000
W50-W64 Exposure to animate mechanical forces	0.773	0.227	0.000
B36 Other superficial mycoses	0.772	0.228	0.000
N04.1 Focal and segmental glomerular lesions	0.772	0.228	0.000
B02.3 Zoster ocular disease	0.771	0.229	0.000
E03.8 Other specified hypothyroidism	0.770	0.230	0.000
X20-X29 Contact with venomous animals and plants	0.770	0.230	0.000
E14.5 With peripheral circulatory complications	0.769	0.231	0.000
E55 Vitamin D deficiency	0.768	0.232	0.000
B01 Varicella [chickenpox]	0.768	0.232	0.000
C91 Lymphoid leukaemia	0.768	0.232	0.000
G50 Disorders of trigeminal nerve	0.768	0.232	0.000
Y57 Other and unspecified drugs and medicaments	0.767	0.233	0.000
D61.1 Drug-induced aplastic anaemia	0.767	0.233	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.766	0.234	0.000
D84 Other immunodeficiencies	0.766	0.234	0.000
D55-D59 Haemolytic anaemias	0.766	0.234	0.000
B00 Herpesviral [herpes simplex] infections	0.765	0.235	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.765	0.235	0.000
H46 Optic neuritis	0.765	0.235	0.000
I10-I15 Hypertensive diseases	0.764	0.236	0.000
G31.0 Circumscribed brain atrophy	0.763	0.237	0.000
Y42.2 Antithyroid drugs	0.762	0.238	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.762	0.238	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.761	0.239	0.000
A63.0 Anogenital (venereal) warts	0.761	0.239	0.000
Q43 Other congenital malformations of intestine	0.761	0.239	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.760	0.240	0.000
I62 Other nontraumatic intracranial haemorrhage	0.760	0.240	0.000
V20-V29 Motorcycle rider injured in transport accident	0.759	0.241	0.000
E28 Ovarian dysfunction	0.759	0.241	0.000
M22 Disorders of patella	0.758	0.242	0.000
V01-V09 Pedestrian injured in transport accident	0.758	0.242	0.000
N42.2 Atrophy of prostate	0.000	0.242	0.758
W19.3 Sports and athletics area	0.757	0.243	0.000
M17 Gonarthrosis [arthrosis of knee]	0.756	0.244	0.000
E24.0 Pituitary-dependent Cushing's disease	0.755	0.245	0.000
E16.1 Other hypoglycaemia	0.755	0.245	0.000
J41 Simple and mucopurulent chronic bronchitis	0.755	0.245	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.754	0.246	0.000
A80-A89 Viral infections of the central nervous system	0.753	0.247	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.753	0.247	0.000
E20 Hypoparathyroidism	0.753	0.247	0.000
M24.1 Other articular cartilage disorders	0.753	0.247	0.000
C83.7 Burkitt's tumour	0.752	0.248	0.000
D86.3 Sarcoidosis of skin	0.751	0.248	0.000
W14 Fall from tree	0.750	0.250	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.750	0.250	0.000
H04.1 Other disorders of lachrymal gland	0.749	0.251	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.748	0.252	0.000
D69.0 Allergic purpura	0.748	0.252	0.000
K40-K46 Hernia	0.043	0.254	0.703
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.746	0.254	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.745	0.254	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.745	0.255	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.745	0.255	0.000
E51 Thiamine deficiency	0.745	0.255	0.000
E78.6 Lipoprotein deficiency	0.745	0.255	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.744	0.256	0.000
D53 Other nutritional anaemias	0.744	0.256	0.000
N05.8 Other	0.744	0.256	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.744	0.256	0.000
M60 Myositis	0.743	0.257	0.000
J98 Other respiratory disorders	0.743	0.257	0.000
H43-H45 Disorders of vitreous body and globe	0.743	0.257	0.000
W19.1 Residential institution	0.742	0.258	0.000
N18.4 Chronic kidney disease, stage 4	0.742	0.258	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.741	0.259	0.000
C84.5 Other and unspecified T-cell lymphomas	0.740	0.260	0.000
M24.7 Protrusio acetabuli	0.740	0.260	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.740	0.260	0.000
Q76 Congenital malformations of spine and bony thorax	0.738	0.262	0.000
Q00-Q07 Congenital malformations of the nervous system	0.738	0.262	0.000
E88.2 Lipomatosis, not elsewhere classified	0.738	0.262	0.000
M33.1 Other dermatomyositis	0.736	0.264	0.000
M65-M68 Disorders of synovium and tendon	0.736	0.264	0.000
C84.0 Mycosis fungoides	0.735	0.265	0.000
N45 Orchitis and epididymitis	0.000	0.265	0.735
D86.8 Sarcoidosis of other and combined sites	0.734	0.266	0.000
G70-G73 Diseases of myoneural junction and muscle	0.734	0.266	0.000
H53-H54 Visual disturbances and blindness	0.734	0.266	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.732	0.268	0.000
A41 Other septicaemia	0.732	0.268	0.000
Q51 Congenital malformations of uterus and cervix	0.731	0.269	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.731	0.269	0.000
E23.2 Diabetes insipidus	0.730	0.270	0.000
N18.1 Chronic kidney disease, stage 1	0.730	0.270	0.000
E78.4 Other hyperlipidaemia	0.730	0.270	0.000
K52.3 Indeterminate colitis	0.728	0.270	0.001
K72.9 Hepatic failure, unspecified	0.728	0.272	0.000
D61.0 Constitutional aplastic anaemia	0.727	0.273	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.273	0.726
N25-N29 Other disorders of kidney and ureter	0.726	0.274	0.000
E07.8 Other specified disorders of thyroid	0.725	0.275	0.000
W13.9 Unspecified place	0.725	0.275	0.000
E11.8 With unspecified complications	0.724	0.276	0.000
N46 Male infertility	0.000	0.276	0.724
B16 Acute hepatitis B	0.721	0.278	0.000
M35.1 Other overlap syndromes	0.721	0.279	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.721	0.279	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.721	0.279	0.000
E84 Cystic fibrosis	0.720	0.280	0.000
D69.5 Secondary thrombocytopenia	0.720	0.280	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.720	0.280	0.000
W18 Other fall on same level	0.720	0.280	0.000
E06.9 Thyroiditis, unspecified	0.719	0.281	0.000
K44 Diaphragmatic hernia	0.016	0.282	0.703
E14.4 With neurological complications	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
D82 Immunodeficiency associated with other major defects	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.716	0.283	0.000
D64.3 Other sideroblastic anaemias	0.716	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.716	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.716	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.716	0.283	0.000
E14.7 With multiple complications	0.716	0.283	0.000
E14.0 With coma	0.716	0.283	0.000
G52 Disorders of other cranial nerves	0.716	0.284	0.000
B37.2 Candidiasis of skin and nail	0.716	0.284	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.715	0.284	0.000
N03 Chronic nephritic syndrome	0.716	0.284	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.715	0.285	0.000
N06 Isolated proteinuria with specified morphological lesion	0.715	0.285	0.000
N01 Rapidly progressive nephritic syndrome	0.715	0.285	0.000
N00 Acute nephritic syndrome	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
E53.8 Deficiency of other specified B group vitamins	0.715	0.285	0.000
E78.2 Mixed hyperlipidaemia	0.714	0.286	0.000
D69.9 Haemorrhagic condition, unspecified	0.714	0.286	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.714	0.286	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.714	0.286	0.000
N18.8 Other chronic renal failure	0.714	0.286	0.000
H30.9 Chorioretinal inflammation, unspecified	0.714	0.286	0.000
R04.0 Epistaxis	0.000	0.286	0.714
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.713	0.287	0.000
B48 Other mycoses, not elsewhere classified	0.713	0.287	0.000
B47 Mycetoma	0.713	0.287	0.000
B46 Zygomycosis	0.713	0.287	0.000
B45 Cryptococcosis	0.713	0.287	0.000
B43 Chromomycosis and phaeomycotic abscess	0.713	0.287	0.000
B42 Sporotrichosis	0.713	0.287	0.000
B41 Paracoccidioidomycosis	0.713	0.287	0.000
B40 Blastomycosis	0.713	0.287	0.000
B39 Histoplasmosis	0.713	0.287	0.000
B38 Coccidioidomycosis	0.713	0.287	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.713	0.287	0.000
Y52.1 Calcium-channel blockers	0.713	0.287	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.713	0.287	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.713	0.287	0.000
C85.0 Lymphosarcoma	0.713	0.287	0.000
J45.8 Mixed asthma	0.713	0.287	0.000
B44.9 Aspergillosis, unspecified	0.712	0.288	0.000
E21.3 Hyperparathyroidism, unspecified	0.712	0.288	0.000
B37.6 Candidal endocarditis	0.711	0.289	0.000
B37.5 Candidal meningitis	0.711	0.289	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.711	0.289	0.000
N05.6 Dense deposit disease	0.710	0.290	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations