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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2535303
log Bayes Factor = 137.4
Chromosome 6   position 31,055,423  (GRCh37) Explore rs2535303 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.999 0.001 0.000
E07 Other disorders of thyroid
0.000 0.001 0.999
E07.9 Disorder of thyroid, unspecified
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.989 0.011 0.000
L40.0 Psoriasis vulgaris
0.985 0.015 0.000
E83.1 Disorders of iron metabolism
0.971 0.029 0.000
C61 Malignant neoplasm of prostate
0.925 0.075 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.151 0.849
L40.4 Guttate psoriasis
0.817 0.183 0.000
E03.8 Other specified hypothyroidism
0.000 0.196 0.804
L40.3 Pustulosis palmaris et plantaris
0.791 0.209 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.241 0.759
K90 Intestinal malabsorption
0.000 0.243 0.757
L40.1 Generalised pustular psoriasis
0.737 0.262 0.000
E06 Thyroiditis
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E07.1 Dyshormogenetic goitre
0.000 0.284 0.716
E07.0 Hypersecretion of calcitonin
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
E07.8 Other specified disorders of thyroid
0.000 0.296 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.305 0.695
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.326 0.674
E05.8 Other thyrotoxicosis
0.000 0.337 0.662
L40.8 Other psoriasis
0.647 0.352 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.384 0.616
E03.1 Congenital hypothyroidism without goitre
0.000 0.397 0.603
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.419 0.581
E06.5 Other chronic thyroiditis
0.000 0.422 0.578
E06.3 Autoimmune thyroiditis
0.000 0.426 0.574
K90.8 Other intestinal malabsorption
0.000 0.450 0.550
K90.3 Pancreatic steatorrhoea
0.000 0.457 0.543
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.457 0.543
K90.1 Tropical sprue
0.000 0.457 0.543
E06.4 Drug-induced thyroiditis
0.000 0.483 0.517
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.483 0.517
E06.0 Acute thyroiditis
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M35.0 Sicca syndrome [Sjogren]
0.000 0.489 0.511
E06.1 Subacute thyroiditis
0.000 0.497 0.503
E10.9 Without complications
0.000 0.505 0.495
E10 Insulin-dependent diabetes mellitus
0.000 0.519 0.481
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.534 0.466
E10-E14 Diabetes mellitus
0.000 0.536 0.464
E10.3 With ophthalmic complications
0.000 0.542 0.458
E10.2 With renal complications
0.000 0.587 0.413
E06.9 Thyroiditis, unspecified
0.000 0.650 0.349
E10.7 With multiple complications
0.000 0.653 0.347
E14 Unspecified diabetes mellitus
0.000 0.661 0.339
E10.0 With coma
0.000 0.663 0.337
E20-E35 Disorders of other endocrine glands
0.000 0.665 0.335
C60-C63 Malignant neoplasms of male genital organs
0.334 0.666 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.667 0.333
E28 Ovarian dysfunction
0.000 0.677 0.323
C83.3 Large cell (diffuse)
0.000 0.678 0.322
E40-E46 Malnutrition
0.000 0.680 0.320
E10.4 With neurological complications
0.000 0.682 0.318
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.690 0.310
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.692 0.308
E28.3 Primary ovarian failure
0.000 0.694 0.306
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.694 0.306
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.694 0.306
E14.3 With ophthalmic complications
0.000 0.697 0.303
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.699 0.301
C85.1 B-cell lymphoma, unspecified
0.000 0.701 0.299
C81 Hodgkin's disease
0.000 0.708 0.292
E10.8 With unspecified complications
0.000 0.708 0.292
E23 Hypofunction and other disorders of pituitary gland
0.000 0.709 0.291
E13 Other specified diabetes mellitus
0.000 0.713 0.287
E10.6 With other specified complications
0.000 0.715 0.285
E24 Cushing's syndrome
0.000 0.717 0.283
E28.2 Polycystic ovarian syndrome
0.000 0.725 0.275
C81.9 Hodgkin's disease, unspecified
0.000 0.728 0.272
E14.5 With peripheral circulatory complications
0.000 0.731 0.269
E23.2 Diabetes insipidus
0.000 0.731 0.269
C60 Malignant neoplasm of penis
0.266 0.734 0.000
E10.1 With ketoacidosis
0.000 0.745 0.255
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.745 0.254
L40-L45 Papulosquamous disorders
0.254 0.746 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.748 0.252
E14.1 With ketoacidosis
0.000 0.751 0.249
E14.8 With unspecified complications
0.000 0.752 0.248
C83.7 Burkitt's tumour
0.000 0.753 0.247
C81.2 Mixed cellularity
0.000 0.754 0.246
E10.5 With peripheral circulatory complications
0.000 0.755 0.244
E14.7 With multiple complications
0.000 0.757 0.243
E14.0 With coma
0.000 0.757 0.243
E31 Polyglandular dysfunction
0.000 0.757 0.243
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.759 0.240
E32 Diseases of thymus
0.000 0.759 0.240
E30 Disorders of puberty, not elsewhere classified
0.000 0.759 0.240
E14.6 With other specified complications
0.000 0.760 0.240
E12.9 Without complications
0.000 0.761 0.239
E12.8 With unspecified complications
0.000 0.761 0.239
E12.7 With multiple complications
0.000 0.761 0.239
E12.6 With other specified complications
0.000 0.761 0.239
E12.5 With peripheral circulatory complications
0.000 0.761 0.239
E12.4 With neurological complications
0.000 0.761 0.239
E12.3 With ophthalmic complications
0.000 0.761 0.239
E12.2 With renal complications
0.000 0.761 0.239
E12.1 With ketoacidosis
0.000 0.761 0.239
E12.0 With coma
0.000 0.761 0.239
C81.1 Nodular sclerosis
0.000 0.762 0.238
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.766 0.234
E14.2 Withrenal complications
0.000 0.767 0.233
E28.9 Ovarian dysfunction, unspecified
0.000 0.768 0.232
E28.8 Other ovarian dysfunction
0.000 0.768 0.232
E28.1 Androgen excess
0.000 0.768 0.232
E28.0 Oestrogen excess
0.000 0.768 0.232
C63 Malignant neoplasm of other and unspecified male genital organs
0.231 0.769 0.000
C81.0 Lymphocytic predominance
0.000 0.770 0.230
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.770 0.229
E45 Retarded development following protein-energy malnutrition
0.000 0.770 0.229
E43 Unspecified severe protein-energy malnutrition
0.000 0.770 0.229
E42 Marasmic kwashiorkor
0.000 0.770 0.229
E41 Nutritional marasmus
0.000 0.770 0.229
E40 Kwashiorkor
0.000 0.770 0.229
E23.7 Disorder of pituitary gland, unspecified
0.000 0.773 0.227
E23.6 Other disorders of pituitary gland
0.000 0.773 0.227
C83.1 Small cleaved cell (diffuse)
0.000 0.773 0.227
E14.4 With neurological complications
0.000 0.775 0.225
E13.3 With ophthalmic complications
0.000 0.776 0.224
C85.0 Lymphosarcoma
0.000 0.778 0.222
C83.6 Undifferentiated (diffuse)
0.000 0.781 0.219
C83.4 Immunoblastic (diffuse)
0.000 0.781 0.219
C83.2 Mixed small and large cell (diffuse)
0.000 0.781 0.219
E15 Nondiabetic hypoglycaemic coma
0.000 0.781 0.219
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.783 0.217
C86 Other specified types of T/NK-cell lymphoma
0.000 0.784 0.216
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.784 0.216
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.784 0.215
E46 Unspecified protein-energy malnutrition
0.000 0.785 0.215
E20 Hypoparathyroidism
0.000 0.786 0.214
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.788 0.212
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.790 0.210
C81.3 Lymphocytic depletion
0.000 0.790 0.210
C88 Malignant immunoproliferative diseases
0.000 0.790 0.209
E26 Hyperaldosteronism
0.000 0.790 0.209
E25 Adrenogenital disorders
0.000 0.791 0.209
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.791 0.209
E23.1 Drug-induced hypopituitarism
0.000 0.791 0.209
E24.0 Pituitary-dependent Cushing's disease
0.000 0.792 0.208
C60.9 Penis, unspecified
0.208 0.792 0.000
C93 Monocytic leukaemia
0.000 0.793 0.207
C83.5 Lymphoblastic (diffuse)
0.000 0.793 0.207
E50-E64 Other nutritional deficiencies
0.000 0.793 0.207
E13.8 With unspecified complications
0.000 0.794 0.206
E13.7 With multiple complications
0.000 0.794 0.206
E13.6 With other specified complications
0.000 0.794 0.206
E13.5 With peripheral circulatory complications
0.000 0.794 0.206
E13.4 With neurological complications
0.000 0.794 0.206
E13.2 With renal complications
0.000 0.794 0.206
E13.1 With ketoacidosis
0.000 0.794 0.206
E13.0 With coma
0.000 0.794 0.206
C60.1 Glans penis
0.204 0.796 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.797 0.203
E24.3 Ectopic ACTH syndrome
0.000 0.797 0.203
E24.1 Nelson's syndrome
0.000 0.797 0.203
L41 Parapsoriasis
0.203 0.797 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.798 0.202
C95 Leukaemia of unspecified cell type
0.000 0.798 0.201
C94 Other leukaemias of specified cell type
0.000 0.799 0.201
M35 Other systemic involvement of connective tissue
0.000 0.799 0.201
C92 Myeloid leukaemia
0.000 0.801 0.199
E24.8 Other Cushing's syndrome
0.000 0.801 0.199
E29 Testicular dysfunction
0.000 0.804 0.196
C81.7 Other Hodgkin's disease
0.000 0.805 0.195
C92.1 Chronic myeloid leukaemia
0.000 0.808 0.192
C60.8 Overlapping lesion of penis
0.191 0.809 0.000
C60.2 Body of penis
0.191 0.809 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.810 0.190
C60.0 Prepuce
0.190 0.810 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.813 0.187
C62 Malignant neoplasm of testis
0.183 0.817 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.182 0.818 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.818 0.182
L44 Other papulosquamous disorders
0.182 0.818 0.000
C82.3 Follicular lymphoma grade IIIa
0.000 0.818 0.181
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.820 0.180
E31.0 Autoimmune polyglandular failure
0.000 0.824 0.176
E31.9 Polyglandular dysfunction, unspecified
0.000 0.826 0.174
E31.8 Other polyglandular dysfunction
0.000 0.826 0.174
E31.1 Polyglandular hyperfunction
0.000 0.826 0.174
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.826 0.173
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.827 0.173
E30.9 Disorder of puberty, unspecified
0.000 0.827 0.173
E30.8 Other disorders of puberty
0.000 0.827 0.173
E30.1 Precocious puberty
0.000 0.827 0.173
E30.0 Delayed puberty
0.000 0.827 0.173
E32.9 Disease of thymus, unspecified
0.000 0.827 0.173
E32.8 Other diseases of thymus
0.000 0.827 0.173
E32.1 Abscess of thymus
0.000 0.827 0.173
E32.0 Persistent hyperplasia of thymus
0.000 0.827 0.173
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.827 0.173
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.827 0.173
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.827 0.173
C84.0 Mycosis fungoides
0.000 0.828 0.172
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.830 0.170
E21.2 Other hyperparathyroidism
0.000 0.831 0.169
M35.7 Hypermobility syndrome
0.000 0.833 0.167
L41.1 Pityriasis lichenoides chronica
0.166 0.834 0.000
C63.9 Male genital organ, unspecified
0.166 0.834 0.000
C63.8 Overlapping lesion of male genital organs
0.166 0.834 0.000
C63.7 Other specified male genital organs
0.166 0.834 0.000
C63.1 Spermatic cord
0.166 0.834 0.000
C63.0 Epididymis
0.166 0.834 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.834 0.166
E44.1 Mild protein-energy malnutrition
0.000 0.835 0.165
E44.0 Moderate protein-energy malnutrition
0.000 0.835 0.165
E34 Other endocrine disorders
0.000 0.836 0.164
C82.2 Large cell, follicular
0.000 0.837 0.163
L42 Pityriasis rosea
0.162 0.838 0.000
C84.5 Other and unspecified T-cell lymphomas
0.000 0.839 0.160
C63.2 Scrotum
0.157 0.843 0.000
E51 Thiamine deficiency
0.000 0.843 0.157
E21.4 Other specified disorders of parathyroid gland
0.000 0.844 0.156
C82.6 Cutaneous follicle centre lymphoma
0.000 0.844 0.156
C82.5 Diffuse follicle centre lymphoma
0.000 0.844 0.156
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.844 0.156
E22 Hyperfunction of pituitary gland
0.000 0.845 0.155
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.845 0.155
C86.4 Blastic NK-cell lymphoma
0.000 0.845 0.155
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.845 0.155
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.845 0.155
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.845 0.155
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.845 0.155
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.845 0.155
C96.8 Histiocytic sarcoma
0.000 0.845 0.155
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.845 0.155
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.845 0.155
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.845 0.155
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.845 0.155
C96.3 True histiocytic lymphoma
0.000 0.845 0.155
C96.2 Malignant mast cell tumour
0.000 0.845 0.155
C96.1 Malignant histiocytosis
0.000 0.845 0.155
C96.0 Letterer-Siwe disease
0.000 0.845 0.155
C95.9 Leukaemia, unspecified
0.000 0.845 0.155
E58 Dietary calcium deficiency
0.000 0.846 0.154
E65-E68 Obesity and other hyperalimentation
0.000 0.846 0.154
E20.8 Other hypoparathyroidism
0.000 0.846 0.154
E20.1 Pseudohypoparathyroidism
0.000 0.846 0.154
E20.0 Idiopathic hypoparathyroidism
0.000 0.846 0.154
M35.8 Other specified systemic involvement of connective tissue
0.000 0.846 0.154
E56 Other vitamin deficiencies
0.000 0.847 0.153
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.848 0.152
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.848 0.152
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.848 0.152
C84.3 Lymphoepithelioid lymphoma
0.000 0.848 0.152
C84.2 T-zone lymphoma
0.000 0.848 0.152
C84.1 Sezary's diease
0.000 0.848 0.152
M35.2 Behcet's disease
0.000 0.849 0.151
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.850 0.150
C88.7 Other malignant immunoproliferative diseases
0.000 0.850 0.150
C88.3 Immunoproliferative small intestinal disease
0.000 0.850 0.150
C88.2 Gamma heavy chain disease
0.000 0.850 0.150
C88.1 Alpha heavy chain disease
0.000 0.850 0.150
E26.9 Hyperaldosteronism, unspecified
0.000 0.850 0.150
E26.8 Other hyperaldosteronism
0.000 0.850 0.150
E26.1 Secondary hyperaldosteronism
0.000 0.850 0.150
E25.9 Adrenogenital disorder, unspecified
0.000 0.850 0.150
E25.8 Other adrenogenital disorders
0.000 0.850 0.150
M35.1 Other overlap syndromes
0.000 0.851 0.149
C93.9 Monocytic leukaemia, unspecified
0.000 0.851 0.149
C93.7 Other monocytic leukaemia
0.000 0.851 0.149
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.851 0.149
C93.2 Subacute monocytic leukaemia
0.000 0.851 0.149
C93.0 Acute monocytic leukaemia
0.000 0.851 0.149
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.852 0.148
E63 Other nutritional deficiencies
0.000 0.852 0.148
E50 Vitamin A deficiency
0.000 0.852 0.148
E60 Dietary zinc deficiency
0.000 0.852 0.148
E59 Dietary selenium deficiency
0.000 0.852 0.148
E52 Niacin deficiency [pellagra]
0.000 0.852 0.148
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.852 0.148
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.853 0.147
L41.9 Parapsoriasis, unspecified
0.145 0.854 0.000
L41.8 Other parapsoriasis
0.145 0.854 0.000
L41.5 Retiform parapsoriasis
0.145 0.854 0.000
L41.4 Large plaque parapsoriasis
0.145 0.854 0.000
L41.3 Small plaque parapsoriasis
0.145 0.854 0.000
L41.2 Lymphomatoid papulosis
0.145 0.854 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.145 0.854 0.000
C95.7 Other leukaemia of unspecified cell type
0.000 0.855 0.145
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.855 0.145
C94.7 Other specified leukaemias
0.000 0.856 0.144
C94.5 Acute myelofibrosis
0.000 0.856 0.144
C94.4 Acute panmyelosis
0.000 0.856 0.144
C94.3 Mast cell leukaemia
0.000 0.856 0.144
C94.2 Acute megakaryoblastic leukaemia
0.000 0.856 0.144
C94.1 Chronic erythraemia
0.000 0.856 0.144
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.856 0.144
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.856 0.144
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.856 0.144
M35.5 Multifocal fibrosclerosis
0.000 0.856 0.144
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.856 0.144
E61 Deficiency of other nutrient elements
0.000 0.856 0.144
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.857 0.143
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.857 0.143
C92.3 Myeloid sarcoma
0.000 0.857 0.143
C92.2 Subacute myeloid leukaemia
0.000 0.857 0.143
E29.8 Other testicular dysfunction
0.000 0.859 0.141
E29.0 Testicular hyperfunction
0.000 0.859 0.141
C93.1 Chronic monocytic leukaemia
0.000 0.859 0.140
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.859 0.140
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.860 0.140
C92.5 Acute myelomonocytic leukaemia
0.000 0.860 0.140
E29.9 Testicular dysfunction, unspecified
0.000 0.862 0.138
C82.4 Follicular lymphoma grade IIIb
0.000 0.862 0.138
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.863 0.136
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.863 0.136
E16.4 Abnormal secretion of gastrin
0.000 0.863 0.136
E16.3 Increased secretion of glucagon
0.000 0.863 0.136
C82.0 Small cleaved cell, follicular
0.000 0.864 0.136
E34.8 Other specified endocrine disorders
0.000 0.866 0.134
E54 Ascorbic acid deficiency
0.000 0.868 0.132
C62.0 Undescended testis
0.131 0.869 0.000
L44.9 Papulosquamous disorder, unspecified
0.130 0.869 0.000
L44.8 Other specified papulosquamous disorders
0.130 0.869 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.130 0.869 0.000
L44.3 Lichen ruber moniliformis
0.130 0.869 0.000
L44.2 Lichen striatus
0.130 0.869 0.000
L44.1 Lichen nitidus
0.130 0.869 0.000
L44.0 Pityriasis rubra pilaris
0.130 0.870 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.871 0.129
C62.1 Descended testis
0.128 0.872 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.873 0.127
H00.1 Chalazion
0.127 0.873 0.000
C92.9 Myeloid leukaemia, unspecified
0.000 0.874 0.126
E13.9 Without complications
0.000 0.875 0.125
E34.3 Short stature, not elsewhere classified
0.000 0.876 0.124
E16.1 Other hypoglycaemia
0.000 0.876 0.124
C95.0 Acute leukaemia of unspecified cell type
0.000 0.878 0.122
E51.2 Wernicke's encephalopathy
0.000 0.879 0.121
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.880 0.120
C84.4 Peripheral T-cell lymphoma
0.000 0.880 0.120
E26.0 Primary hyperaldosteronism
0.000 0.881 0.119
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.881 0.119
E34.5 Androgen resistance syndrome
0.000 0.882 0.118
E34.4 Constitutional tall stature
0.000 0.882 0.118
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.882 0.118
E34.1 Other hypersecretion of intestinal hormones
0.000 0.882 0.118
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.883 0.117
K60.2 Anal fissure, unspecified
0.000 0.884 0.116
E56.1 Deficiency of vitamin K
0.000 0.885 0.114
C91 Lymphoid leukaemia
0.000 0.886 0.114
E27 Other disorders of adrenal gland
0.000 0.886 0.114
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.887 0.112
E61.2 Magnesium deficiency
0.000 0.887 0.113
E51.9 Thiamine deficiency, unspecified
0.000 0.887 0.112
E51.8 Other manifestations of thiamine deficiency
0.000 0.887 0.112
E51.1 Beriberi
0.000 0.887 0.112
E22.8 Other hyperfunction of pituitary gland
0.000 0.888 0.111
C92.4 Acute promyelocytic leukaemia
0.000 0.889 0.111
E67 Other hyperalimentation
0.000 0.889 0.110
E68 Sequelae of hyperalimentation
0.000 0.889 0.110
E56.9 Vitamin deficiency, unspecified
0.000 0.890 0.110
E56.8 Deficiency of other vitamins
0.000 0.890 0.110
E56.0 Deficiency of vitamin E
0.000 0.890 0.110
K60 Fissure and fistula of anal and rectal regions
0.000 0.891 0.109
C92.7 Other myeloid leukaemia
0.000 0.893 0.107
E50.9 Vitamin A deficiency, unspecified
0.000 0.893 0.106
E50.8 Other manifestations of vitamin A deficiency
0.000 0.893 0.106
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.893 0.106
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.893 0.106
E50.5 Vitamin A deficiency with night blindness
0.000 0.893 0.106
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.893 0.106
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.893 0.106
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.893 0.106
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.893 0.106
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.893 0.106
E63.9 Nutritional deficiency, unspecified
0.000 0.893 0.106
E63.8 Other specified nutritional deficiencies
0.000 0.893 0.106
E63.1 Imbalance of constituents of food intake
0.000 0.893 0.106
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.893 0.106
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.893 0.106
E64.8 Sequelae of other nutritional deficiencies
0.000 0.893 0.106
E64.3 Sequelae of rickets
0.000 0.893 0.106
E64.2 Sequelae of vitamin C deficiency
0.000 0.893 0.106
E64.1 Sequelae of vitamin A deficiency
0.000 0.893 0.106
E64.0 Sequelae of protein-energy malnutrition
0.000 0.893 0.106
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.895 0.105
K60.3 Anal fistula
0.000 0.895 0.105
C83.0 Small cell (diffuse)
0.000 0.896 0.103
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.896 0.103
E61.9 Deficiency of nutrient element, unspecified
0.000 0.897 0.103
E61.8 Deficiency of other specified nutrient elements
0.000 0.897 0.103
E61.7 Deficiency of multiple nutrient elements
0.000 0.897 0.103
E61.6 Vanadium deficiency
0.000 0.897 0.103
E61.5 Molybdenum deficiency
0.000 0.897 0.103
E61.4 Chromium deficiency
0.000 0.897 0.103
E61.3 Manganese deficiency
0.000 0.897 0.103
E61.0 Copper deficiency
0.000 0.897 0.103
E53 Deficiency of other B group vitamins
0.000 0.898 0.102
E29.1 Testicular hypofunction
0.000 0.898 0.101
K60.0 Acute anal fissure
0.000 0.899 0.101
E55 Vitamin D deficiency
0.000 0.900 0.099
E23.0 Hypopituitarism
0.000 0.901 0.099
C91.9 Lymphoid leukaemia, unspecified
0.000 0.903 0.097
E22.1 Hyperprolactinaemia
0.000 0.905 0.094
K60.5 Anorectal fistula
0.000 0.907 0.093
E65 Localised adiposity
0.000 0.912 0.087
L43 Lichen planus
0.086 0.913 0.001
E27.1 Primary adrenocortical insufficiency
0.000 0.913 0.087
E61.1 Iron deficiency
0.000 0.914 0.086
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.916 0.083
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.918 0.082
C91.7 Other lymphoid leukaemia
0.000 0.918 0.082
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.918 0.082
C91.3 Prolymphocytic leukaemia
0.000 0.918 0.082
C91.2 Subacute lymphocytic leukaemia
0.000 0.918 0.082
C91.5 Adult T-cell leukaemia
0.000 0.918 0.082
E27.5 Adrenomedullary hyperfunction
0.000 0.918 0.082
E27.0 Other adrenocortical overactivity
0.000 0.918 0.082
C62.9 Testis, unspecified
0.081 0.919 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.920 0.080
E67.8 Other specified hyperalimentation
0.000 0.920 0.079
E67.3 Hypervitaminosis D
0.000 0.920 0.079
E67.2 Megavitamin-B6 syndrome
0.000 0.920 0.079
E67.1 Hypercarotenaemia
0.000 0.920 0.079
E67.0 Hypervitaminosis A
0.000 0.920 0.079
K60.4 Rectal fistula
0.000 0.920 0.079
E21.0 Primary hyperparathyroidism
0.000 0.923 0.077
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.923 0.077
H00 Hordeolum and chalazion
0.075 0.925 0.000
E53.1 Pyridoxine deficiency
0.000 0.927 0.073
E53.0 Riboflavin deficiency
0.000 0.927 0.073
E55.0 Rickets, active
0.000 0.928 0.071
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.930 0.070
E14.9 Without complications
0.000 0.932 0.068
E53.9 Vitamin B deficiency, unspecified
0.000 0.933 0.067
C91.4 Hairy-cell leukaemia
0.000 0.934 0.066
E34.9 Endocrine disorder, unspecified
0.001 0.934 0.065
C90.1 Plasma cell leukaemia
0.001 0.935 0.065
E22.0 Acromegaly and pituitary gigantism
0.000 0.935 0.064
H00.0 Hordeolum and other deep inflammation of eyelid
0.064 0.936 0.000
E34.0 Carcinoid syndrome
0.001 0.937 0.062
E04 Other non-toxic goitre
0.000 0.937 0.063
C92.0 Acute myeloid leukaemia
0.000 0.937 0.063
L43.3 Subacute (active) lichen planus
0.062 0.937 0.001
L43.2 Lichenoid drug reaction
0.062 0.937 0.001
L43.1 Bullous lichen planus
0.062 0.937 0.001
L43.0 Hypertrophic lichen planus
0.062 0.937 0.001
E27.2 Addisonian crisis
0.000 0.939 0.061
C91.0 Acute lymphoblastic leukaemia
0.000 0.940 0.060
C90.3 Solitary plasmacytoma
0.001 0.942 0.057
L43.8 Other lichen planus
0.050 0.950 0.001
K90-K93 Other diseases of the digestive system
0.000 0.953 0.047
E04.8 Other specified non-toxic goitre
0.000 0.955 0.045
E16.2 Hypoglycaemia, unspecified
0.000 0.956 0.044
E83 Disorders of mineral metabolism
0.041 0.956 0.003
E27.8 Other specified disorders of adrenal gland
0.000 0.956 0.043
N05.2 Diffuse membranous glomerulonephritis
0.000 0.956 0.043
N05.9 Unspecified
0.000 0.957 0.042
N05 Unspecified nephritic syndrome
0.000 0.958 0.042
E53.8 Deficiency of other specified B group vitamins
0.000 0.961 0.039
E04.0 Non-toxic diffuse goitre
0.000 0.961 0.039
M35.3 Polymyalgia rheumatica
0.000 0.962 0.038
Z51.3 Blood transfusion without reported diagnosis
0.000 0.962 0.038
N05.1 Focal and segmental glomerular lesions
0.000 0.964 0.036
K60.1 Chronic anal fissure
0.000 0.964 0.036
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.965 0.035
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.966 0.034
C90.2 Plasmacytoma, extramedullary
0.001 0.967 0.031
E83.9 Disorder of mineral metabolism, unspecified
0.030 0.967 0.002
E83.8 Other disorders of mineral metabolism
0.029 0.968 0.003
E83.2 Disorders of zinc metabolism
0.029 0.968 0.003
E83.0 Disorders of copper metabolism
0.029 0.968 0.003
K50.0 Crohn's disease of small intestine
0.032 0.968 0.000
N05.6 Dense deposit disease
0.000 0.969 0.031
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.969 0.031
N05.0 Minor glomerular abnormality
0.000 0.969 0.031
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.970 0.029
G63.2 Diabetic polyneuropathy
0.028 0.972 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.972 0.028
N05.8 Other
0.000 0.972 0.028
K50.8 Other Crohn's disease
0.025 0.975 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.025 0.975 0.000
K50 Crohn's disease [regional enteritis]
0.025 0.975 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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