TreeWAS – Variant ID: rs2555603

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L29 Pruritus	0.000	0.935	0.065
L29.0 Pruritus ani	0.000	0.935	0.065
L29.9 Pruritus, unspecified	0.000	0.935	0.065
L29.2 Pruritus vulvae	0.000	0.936	0.064
L29.3 Anogenital pruritus, unspecified	0.000	0.953	0.047
L29.1 Pruritus scroti	0.000	0.953	0.047
K65.9 Peritonitis, unspecified	0.042	0.958	0.000
L29.8 Other pruritus	0.000	0.960	0.040
Y43.3 Other antineoplastic drugs	0.034	0.966	0.000
Y43 Primarily systemic agents	0.026	0.974	0.000
Y43.4 Immunosuppressive agents	0.022	0.978	0.000
Y43.1 Antineoplastic antimetabolites	0.021	0.979	0.000
Y43.0 Antiallergic and antiemetic drugs	0.021	0.979	0.000
Y43.9 Primarily systemic agent, unspecified	0.018	0.981	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.018	0.981	0.000
Y43.6 Enzymes, not elsewhere classified	0.018	0.981	0.000
Y43.5 Acidifying and alkalising agents	0.018	0.981	0.000
Y43.2 Antineoplastic natural products	0.018	0.981	0.000
L20-L30 Dermatitis and eczema	0.000	0.983	0.017
Z97.4 Presence of external hearing-aid	0.000	0.983	0.017
L28 Lichen simplex chronicus and prurigo	0.000	0.986	0.014
L25 Unspecified contact dermatitis	0.000	0.986	0.014
L23 Allergic contact dermatitis	0.000	0.987	0.013
L24 Irritant contact dermatitis	0.000	0.987	0.013
L26 Exfoliative dermatitis	0.000	0.987	0.013
L22 Diaper [napkin] dermatitis	0.000	0.987	0.013
L27 Dermatitis due to substances taken internally	0.000	0.988	0.012
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.989	0.011
L20 Atopic dermatitis	0.000	0.989	0.011
L28.1 Prurigo nodularis	0.000	0.989	0.011
L21 Seborrhoeic dermatitis	0.000	0.989	0.011
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.989	0.011
D12.4 Descending colon	0.010	0.990	0.000
L28.0 Lichen simplex chronicus	0.000	0.990	0.010
L28.2 Other prurigo	0.000	0.990	0.010
L25.8 Unspecified contact dermatitis due to other agents	0.000	0.990	0.010
L25.5 Unspecified contact dermatitis due to plants, except food	0.000	0.990	0.010
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.000	0.990	0.010
L25.3 Unspecified contact dermatitis due to other chemical products	0.000	0.990	0.010
L25.2 Unspecified contact dermatitis due to dyes	0.000	0.990	0.010
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.000	0.990	0.010
L25.0 Unspecified contact dermatitis due to cosmetics	0.000	0.990	0.010
K65 Peritonitis	0.010	0.990	0.000
L23.8 Allergic contact dermatitis due to other agents	0.000	0.990	0.010
L23.7 Allergic contact dermatitis due to plants, except food	0.000	0.990	0.010
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.000	0.990	0.010
L23.4 Allergic contact dermatitis due to dyes	0.000	0.990	0.010
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.000	0.990	0.010
L23.2 Allergic contact dermatitis due to cosmetics	0.000	0.990	0.010
L23.0 Allergic contact dermatitis due to metals	0.000	0.990	0.010
C44.7 Skin of lower limb, including hip	0.010	0.990	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.990	0.009
L24.9 Irritant contact dermatitis, unspecified cause	0.000	0.991	0.009
L24.8 Irritant contact dermatitis due to other agents	0.000	0.991	0.009
L24.7 Irritant contact dermatitis due to plants, except food	0.000	0.991	0.009
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.000	0.991	0.009
L24.5 Irritant contact dermatitis due to other chemical products	0.000	0.991	0.009
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.000	0.991	0.009
L24.3 Irritant contact dermatitis due to cosmetics	0.000	0.991	0.009
L24.2 Irritant contact dermatitis due to solvents	0.000	0.991	0.009
L24.1 Irritant contact dermatitis due to oils and greases	0.000	0.991	0.009
L24.0 Irritant contact dermatitis due to detergents	0.000	0.991	0.009
L27.2 Dermatitis due to ingested food	0.000	0.991	0.009
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.991	0.009
L27.8 Dermatitis due to other substances taken internally	0.000	0.991	0.009
E21.0 Primary hyperparathyroidism	0.009	0.991	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.000	0.991	0.009
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.991	0.009
L20.8 Other atopic dermatitis	0.000	0.992	0.008
L20.0 Besnier's prurigo	0.000	0.992	0.008
L21.8 Other seborrhoeic dermatitis	0.000	0.992	0.008
L21.1 Seborrhoeic infantile dermatitis	0.000	0.992	0.008
L21.0 Seborrhoea capitis	0.000	0.992	0.008
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.992	0.008
I45.9 Conduction disorder, unspecified	0.000	0.992	0.008
N64.5 Other signs and symptoms in breast	0.007	0.993	0.000
R27.0 Ataxia, unspecified	0.000	0.993	0.007
L20.9 Atopic dermatitis, unspecified	0.000	0.993	0.007
L30 Other dermatitis	0.000	0.993	0.007
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.993	0.007
K65.0 Acute peritonitis	0.006	0.994	0.000
I86.4 Gastric varices	0.006	0.994	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
Z97 Presence of other devices	0.000	0.994	0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.006	0.994	0.000
D07.5 Prostate	0.006	0.994	0.000
D68.2 Hereditary deficiency of other clotting factors	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.006	0.994	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
L30.3 Infective dermatitis	0.000	0.994	0.005
Y42.7 Androgens and anabolic congeners	0.005	0.995	0.000
Y42.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
K74.3 Primary biliary cirrhosis	0.005	0.995	0.000
L30.4 Erythema intertrigo	0.000	0.995	0.005
K74.6 Other and unspecified cirrhosis of liver	0.005	0.995	0.000
L30.5 Pityriasis alba	0.000	0.995	0.005
L30.2 Cutaneous autosensitisation	0.000	0.995	0.005
L30.1 Dyshidrosis [pompholyx]	0.000	0.995	0.005
L30.0 Nummular dermatitis	0.000	0.995	0.005
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.995	0.005
D68.5 Primary Thrombophilia	0.005	0.995	0.000
Y42.4 Oral contraceptives	0.005	0.995	0.000
Y42.2 Antithyroid drugs	0.005	0.995	0.000
H60.9 Otitis externa, unspecified	0.005	0.995	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.995	0.005
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.995	0.005
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
K74 Fibrosis and cirrhosis of liver	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.004	0.995	0.000
D68.9 Coagulation defect, unspecified	0.005	0.995	0.000
E21.2 Other hyperparathyroidism	0.004	0.995	0.000
Z97.8 Presence of other specified devices	0.000	0.996	0.004
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.996	0.000
N64 Other disorders of breast	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
L30.8 Other specified dermatitis	0.000	0.996	0.004
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
I34.1 Mitral (valve) prolapse	0.000	0.996	0.004
N31.8 Other neuromuscular dysfunction of bladder	0.004	0.996	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
N02.8 Other	0.000	0.996	0.004
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
L40.9 Psoriasis, unspecified	0.004	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.004	0.996	0.000
K74.0 Hepatic fibrosis	0.004	0.996	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.004	0.996	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.996	0.004
N64.9 Disorder of breast, unspecified	0.004	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.996	0.004
S10.9 Superficial injury of neck, part unspecified	0.004	0.996	0.000
K74.4 Secondary biliary cirrhosis	0.004	0.996	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.004	0.996	0.000
K74.1 Hepatic sclerosis	0.004	0.996	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.996	0.004
N64.8 Other specified disorders of breast	0.004	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
N64.4 Mastodynia	0.004	0.996	0.000
Z97.0 Presence of artificial eye	0.000	0.996	0.004
I34 Nonrheumatic mitral valve disorders	0.000	0.996	0.004
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.996	0.004
M79.88 Other specified soft tissue disorders (Other)	0.000	0.996	0.004
K65.8 Other peritonitis	0.003	0.996	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.996	0.000
J30.1 Allergic rhinitis due to pollen	0.004	0.996	0.000
N64.3 Galactorrhoea not associated with childbirth	0.003	0.997	0.000
N64.2 Atrophy of breast	0.003	0.997	0.000
N64.0 Fissure and fistula of nipple	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.997	0.003
S10 Superficial injury of neck	0.003	0.997	0.000
L90.5 Scar conditions and fibrosis of skin	0.003	0.997	0.000
M79.8 Other specified soft tissue disorders	0.000	0.997	0.003
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.997	0.003
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.997	0.003
I86 Varicose veins of other sites	0.003	0.997	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.997	0.003
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
L40.0 Psoriasis vulgaris	0.000	0.997	0.003
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.997	0.003
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.997	0.003
S10.8 Superficial injury of other parts of neck	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
H40.1 Primary open-angle glaucoma	0.000	0.997	0.003
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
I45 Other conduction disorders	0.000	0.997	0.003
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
S19.9 Unspecified injury of neck	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
I86.3 Vulval varices	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
K65-K67 Diseases of peritoneum	0.003	0.997	0.000
R27 Other lack of coordination	0.000	0.997	0.003
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
I45.8 Other specified conduction disorders	0.000	0.997	0.003
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.997	0.000
S10.1 Other and unspecified superficial injuries of throat	0.002	0.997	0.000
S10.0 Contusion of throat	0.002	0.997	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.002	0.997	0.000
I86.2 Pelvic varices	0.002	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.997	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.997	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.997	0.000
Y58 Bacterial vaccines	0.002	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.997	0.000
S11 Open wound of neck	0.002	0.997	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.997	0.003
I86.0 Sublingual varices	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.998	0.002
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
I45.2 Bifascicular block	0.000	0.998	0.002
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
N60.9 Benign mammary dysplasia, unspecified	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
I45.0 Right fascicular block	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.000	0.998	0.002
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.002	0.998	0.000
S19.8 Other specified injuries of neck	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y83.4 Other reconstructive surgery	0.000	0.998	0.002
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
J31.0 Chronic rhinitis	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
I45.4 Nonspecific intraventricular block	0.000	0.998	0.002
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.002	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.000	0.998	0.002
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S05.7 Avulsion of eye	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.002	0.998	0.000
J30 Vasomotor and allergic rhinitis	0.002	0.998	0.000
I45.3 Trifascicular block	0.000	0.998	0.002
J30.3 Other allergic rhinitis	0.002	0.998	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.000	0.998	0.002
N60.3 Fibrosclerosis of breast	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.998	0.002
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.998	0.002
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.002	0.998	0.000
K67.3 Tuberculous peritonitis	0.002	0.998	0.000
K67.2 Syphilitic peritonitis	0.002	0.998	0.000
K67.1 Gonococcal peritonitis	0.002	0.998	0.000
K67.0 Chlamydial peritonitis	0.002	0.998	0.000
M06.8 Other specified rheumatoid arthritis	0.002	0.998	0.000
M84.0 Malunion of fracture	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
C24.1 Ampulla of Vater	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.002	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.002	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.002	0.998	0.000
S15.3 Injury of internal jugular vein	0.002	0.998	0.000
S15.2 Injury of external jugular vein	0.002	0.998	0.000
S15.1 Injury of vertebral artery	0.002	0.998	0.000
S15.0 Injury of carotid artery	0.002	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.002	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.002	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.002	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
F40.0 Agoraphobia	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
B35.1 Tinea unguium	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
I45.5 Other specified heart block	0.000	0.998	0.002
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
N60 Benign mammary dysplasia	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
M77.1 Lateral epicondylitis	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.998	0.002
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
M06 Other rheumatoid arthritis	0.002	0.998	0.000
N18.0 End-stage renal disease	0.000	0.998	0.002
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.001	0.998	0.000
Y46.5 Valproic acid	0.001	0.998	0.000
Y46.3 Deoxybarbiturates	0.001	0.998	0.000
Y46.1 Oxazolidinediones	0.001	0.998	0.000
Y46.0 Succinimides	0.001	0.998	0.000
N64.1 Fat necrosis of breast	0.001	0.998	0.000
Y40.6 Rifamycins	0.001	0.998	0.000
Y40.2 Chloramphenicol group	0.001	0.998	0.000
Y45.4 Antirheumatics	0.001	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
F40.1 Social phobias	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.001	0.998	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.001	0.998	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.001	0.998	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.001	0.998	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.001	0.998	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.001	0.998	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.001	0.998	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.001	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.001
M84.08 Malunion of fracture (Other)	0.000	0.998	0.001
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.998	0.000
C15.3 Upper third of oesophagus	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.998	0.002
M20.2 Hallux rigidus	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.001	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.001
C16.9 Stomach, unspecified	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.998	0.000
S12.8 Fracture of other parts of neck	0.001	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
Y40.4 Tetracyclines	0.001	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
C16.2 Body of stomach	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations