TreeWAS – Variant ID: rs2566255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C18 Malignant neoplasm of colon	0.062	0.938	0.000
C18.0 Caecum	0.061	0.939	0.000
C18.9 Colon, unspecified	0.059	0.941	0.000
C18.3 Hepatic flexure	0.053	0.947	0.000
C18.2 Ascending colon	0.050	0.950	0.000
C18.5 Splenic flexure	0.050	0.950	0.000
C18.4 Transverse colon	0.049	0.951	0.000
C18.7 Sigmoid colon	0.048	0.952	0.000
C18.1 Appendix	0.047	0.953	0.000
C18.6 Descending colon	0.046	0.954	0.000
C18.8 Overlapping lesion of colon	0.042	0.958	0.000
C15-C26 Malignant neoplasms of digestive organs	0.019	0.981	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.018	0.982	0.000
C20 Malignant neoplasm of rectum	0.015	0.985	0.000
C17 Malignant neoplasm of small intestine	0.015	0.985	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.014	0.986	0.000
C15 Malignant neoplasm of oesophagus	0.014	0.986	0.000
C16 Malignant neoplasm of stomach	0.014	0.986	0.000
C23 Malignant neoplasm of gallbladder	0.013	0.987	0.000
C21 Malignant neoplasm of anus and anal canal	0.013	0.987	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.012	0.988	0.000
C17.0 Duodenum	0.012	0.988	0.000
C17.1 Jejunum	0.011	0.988	0.000
C26.0 Intestinal tract, part unspecified	0.011	0.989	0.000
C15.5 Lower third of oesophagus	0.011	0.989	0.000
C50.9 Breast, unspecified	0.011	0.989	0.000
C15.9 Oesophagus, unspecified	0.011	0.989	0.000
C16.2 Body of stomach	0.011	0.989	0.000
C17.8 Overlapping lesion of small intestine	0.011	0.989	0.000
C17.3 Meckel's diverticulum	0.011	0.989	0.000
C26.8 Overlapping lesion of digestive system	0.010	0.989	0.000
C26.1 Spleen	0.010	0.989	0.000
C17.2 Ileum	0.010	0.989	0.000
C26.9 Ill-defined sites within the digestive system	0.010	0.990	0.000
C16.1 Fundus of stomach	0.010	0.990	0.000
C16.5 Lesser curvature of stomach, unspecified	0.010	0.990	0.000
C16.4 Pylorus	0.010	0.990	0.000
C16.6 Greater curvature of stomach, unspecified	0.010	0.990	0.000
C15.8 Overlapping lesion of oesophagus	0.010	0.990	0.000
C15.2 Abdominal part of oesophagus	0.010	0.990	0.000
C16.0 Cardia	0.010	0.990	0.000
C16.8 Overlapping lesion of stomach	0.010	0.990	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.010	0.990	0.000
C15.3 Upper third of oesophagus	0.010	0.990	0.000
C15.0 Cervical part of oesophagus	0.010	0.990	0.000
C21.1 Anal canal	0.010	0.990	0.000
C15.1 Thoracic part of oesophagus	0.010	0.990	0.000
C21.2 Cloacogenic zone	0.009	0.990	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.009	0.991	0.000
C16.9 Stomach, unspecified	0.009	0.991	0.000
C24.8 Overlapping lesion of biliary tract	0.009	0.991	0.000
C16.3 Pyloric antrum	0.009	0.991	0.000
C24.1 Ampulla of Vater	0.009	0.991	0.000
C17.9 Small intestine, unspecified	0.008	0.991	0.000
C21.0 Anus, unspecified	0.008	0.991	0.000
C15.4 Middle third of oesophagus	0.008	0.992	0.000
C24.9 Biliary tract, unspecified	0.008	0.992	0.000
C24.0 Extrahepatic bile duct	0.008	0.992	0.000
C25 Malignant neoplasm of pancreas	0.008	0.992	0.000
A04.8 Other specified bacterial intestinal infections	0.008	0.992	0.000
C22.7 Other specified carcinomas of liver	0.007	0.993	0.000
C22.4 Other sarcomas of liver	0.007	0.993	0.000
C22.3 Angiosarcoma of liver	0.007	0.993	0.000
C22.2 Hepatoblastoma	0.007	0.993	0.000
C22.0 Liver cell carcinoma	0.007	0.993	0.000
Y43.3 Other antineoplastic drugs	0.007	0.993	0.000
C22.1 Intrahepatic bile duct carcinoma	0.006	0.994	0.000
C25.2 Tail of pancreas	0.006	0.994	0.000
C25.3 Pancreatic duct	0.006	0.994	0.000
C25.8 Overlapping lesion of pancreas	0.006	0.994	0.000
C25.7 Other parts of pancreas	0.006	0.994	0.000
C22.9 Liver, unspecified	0.006	0.994	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.994	0.006
C25.4 Endocrine pancreas	0.005	0.994	0.000
C25.1 Body of pancreas	0.005	0.994	0.000
C25.0 Head of pancreas	0.005	0.995	0.000
M43.1 Spondylolisthesis	0.000	0.995	0.005
A04 Other bacterial intestinal infections	0.005	0.995	0.000
N21.0 Calculus in bladder	0.005	0.995	0.000
C25.9 Pancreas, unspecified	0.004	0.995	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.995	0.005
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
A04.9 Bacterial intestinal infection, unspecified	0.004	0.996	0.000
A04.4 Other intestinal Escherichia coli infections	0.004	0.996	0.000
A04.5 Campylobacter enteritis	0.004	0.996	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.996	0.004
Y43 Primarily systemic agents	0.004	0.996	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.996	0.004
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.996	0.004
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.996	0.004
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.996	0.004
M43 Other deforming dorsopathies	0.000	0.996	0.004
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.996	0.004
A04.6 Enteritis due to Yersinia enterocolitica	0.004	0.996	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.004	0.996	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.004	0.996	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.004	0.996	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.004	0.996	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.004	0.996	0.000
M43.12 Spondylolisthesis (Cervical region)	0.000	0.996	0.003
M43.6 Torticollis	0.000	0.996	0.003
M43.62 Torticollis-Cervical	0.000	0.997	0.003
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M43.9 Deforming dorsopathy, unspecified	0.000	0.997	0.003
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
M43.8 Other specified deforming dorsopathies	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
K29.6 Other gastritis	0.003	0.997	0.000
M43.5 Other recurrent vertebral subluxation	0.000	0.997	0.003
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.997	0.003
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.997	0.003
A04.7 Enterocolitis due to Clostridium difficile	0.003	0.997	0.000
M43.0 Spondylolysis	0.000	0.997	0.003
M43.69 Torticollis-Site unspe	0.000	0.997	0.003
M43.68 Torticollis-Sacral/sacrococ	0.000	0.997	0.003
M43.67 Torticollis-Lumbosacral	0.000	0.997	0.003
M43.66 Torticollis-Lumbar	0.000	0.997	0.003
M43.65 Torticollis-Thoracolumbar	0.000	0.997	0.003
M43.64 Torticollis-Thoracic	0.000	0.997	0.003
M43.63 Torticollis-Cervicothoracic	0.000	0.997	0.003
M43.61 Torticollis-Occipit-atl-axl	0.000	0.997	0.003
M43.60 Torticollis-Mult site	0.000	0.997	0.003
M43.2 Other fusion of spine	0.000	0.997	0.003
Z88.5 Personal history of allergy to narcotic agent	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
R15 Faecal incontinence	0.003	0.997	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.000	0.997	0.003
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.000	0.997	0.003
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.000	0.997	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.000	0.997	0.002
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.000	0.997	0.002
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.000	0.997	0.002
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.000	0.997	0.002
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.000	0.997	0.002
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.000	0.997	0.002
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.002
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.000	0.997	0.002
M81.98 Osteoporosis, unspecified (Other)	0.000	0.997	0.003
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.000	0.998	0.002
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.000	0.998	0.002
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.000	0.998	0.002
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.000	0.998	0.002
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.000	0.998	0.002
M43.82 Other specified deforming dorsopathies (Cervical region)	0.000	0.998	0.002
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.000	0.998	0.002
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.000	0.998	0.002
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.000	0.998	0.002
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.000	0.998	0.002
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.000	0.998	0.002
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.000	0.998	0.002
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.000	0.998	0.002
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.000	0.998	0.002
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.000	0.998	0.002
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.000	0.998	0.002
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.000	0.998	0.002
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.000	0.998	0.002
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.000	0.998	0.002
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.000	0.998	0.002
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.000	0.998	0.002
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.000	0.998	0.002
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.000	0.998	0.002
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.000	0.998	0.002
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.000	0.998	0.002
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.000	0.998	0.002
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.000	0.998	0.002
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.000	0.998	0.002
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.000	0.998	0.002
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.000	0.998	0.002
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.000	0.998	0.002
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.000	0.998	0.002
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.000	0.998	0.002
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.000	0.998	0.002
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.998	0.002
M43.04 Spondylolysis (Thoracic region)	0.000	0.998	0.002
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.998	0.002
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.000	0.998	0.002
M43.02 Spondylolysis (Cervical region)	0.000	0.998	0.002
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.27 Other fusion of spine (Lumbosacral region)	0.000	0.998	0.002
M43.26 Other fusion of spine (Lumbar region)	0.000	0.998	0.002
M43.25 Other fusion of spine (Thoracolumbar region)	0.000	0.998	0.002
M43.24 Other fusion of spine (Thoracic region)	0.000	0.998	0.002
M43.23 Other fusion of spine (Cervicothoracic region)	0.000	0.998	0.002
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.20 Other fusion of spine (Multiple sites in spine)	0.000	0.998	0.002
M43.22 Other fusion of spine (Cervical region)	0.000	0.998	0.002
D32.0 Cerebral meninges	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
M43.29 Other fusion of spine (Site unspecified)	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
N21 Calculus of lower urinary tract	0.002	0.998	0.000
R56.8 Other and unspecified convulsions	0.000	0.998	0.002
M48.06 Spinal stenosis (Lumbar region)	0.000	0.998	0.002
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.002	0.998	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
M40-M43 Deforming dorsopathies	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
K62.3 Rectal prolapse	0.002	0.998	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.002	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.002
M40 Kyphosis and lordosis	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.000	0.998	0.002
M40.2 Other and unspecified kyphosis	0.000	0.998	0.002
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.998	0.002
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.002	0.998	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.000	0.998	0.001
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.998	0.001
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.998	0.001
N21.8 Other lower urinary tract calculus	0.001	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
Y45.4 Antirheumatics	0.001	0.998	0.000
Y52.1 Calcium-channel blockers	0.001	0.998	0.000
M42 Spinal osteochondrosis	0.000	0.998	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.001
G25.3 Myoclonus	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.000	0.998	0.001
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M41 Scoliosis	0.000	0.998	0.002
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.000	0.998	0.001
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.998	0.001
C77.4 Inguinal and lower limb lymph nodes	0.001	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.001
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
M40.4 Other lordosis	0.000	0.998	0.001
M40.3 Flatback syndrome	0.000	0.998	0.001
M40.0 Postural kyphosis	0.000	0.998	0.001
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.998	0.002
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
M81.8 Other osteoporosis	0.000	0.998	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.001
D32 Benign neoplasm of meninges	0.000	0.998	0.002
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.000	0.998	0.001
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.000	0.998	0.001
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.000	0.998	0.001
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.000	0.998	0.001
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.998	0.001
F60.9 Personality disorder, unspecified	0.001	0.998	0.000
M40.5 Lordosis, unspecified	0.000	0.998	0.001
M40.1 Other secondary kyphosis	0.000	0.998	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.001
M81.5 Idiopathic osteoporosis	0.000	0.998	0.001
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.998	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
C79.9 Secondary malignant neoplasm, unspecified site	0.001	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.001
M40.22 Other and unspecified kyphosis (Cervical region)	0.000	0.999	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.999	0.001
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
M41.4 Neuromuscular scoliosis	0.000	0.999	0.001
M81.2 Osteoporosis of disuse	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.001	0.999	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.000	0.999	0.001
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M41.87 Other forms of scoliosis (Lumbosacral region)	0.000	0.999	0.001
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.000	0.999	0.001
M41.84 Other forms of scoliosis (Thoracic region)	0.000	0.999	0.001
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.000	0.999	0.001
M41.82 Other forms of scoliosis (Cervical region)	0.000	0.999	0.001
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.000	0.999	0.001
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.999	0.001
M84.01 Malunion of fracture (Shoulder region)	0.000	0.999	0.001
D32.1 Spinal meninges	0.000	0.999	0.001
G25.9 Extrapyramidal and movement disorder, unspecified	0.001	0.999	0.000
M42.9 Spinal osteochondrosis, unspecified	0.000	0.999	0.001
M42.1 Adult osteochondrosis of spine	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.999	0.001
M41.3 Thoracogenic scoliosis	0.000	0.999	0.001
M41.1 Juvenile idiopathic scoliosis	0.000	0.999	0.001
M41.0 Infantile idiopathic scoliosis	0.000	0.999	0.001
M42.0 Juvenile osteochondrosis of spine	0.000	0.999	0.001
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
M81.80 Other osteoporosis (Multiple sites)	0.000	0.999	0.001
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.001	0.999	0.000
G25.1 Drug-induced tremor	0.001	0.999	0.000
M41.2 Other idiopathic scoliosis	0.000	0.999	0.001
Q21.1 Atrial septal defect	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.999	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.999	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
M40.09 Postural kyphosis (Site unspecified)	0.000	0.999	0.001
M40.08 Postural kyphosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.07 Postural kyphosis (Lumbosacral region)	0.000	0.999	0.001
M40.06 Postural kyphosis (Lumbar region)	0.000	0.999	0.001
M40.05 Postural kyphosis (Thoracolumbar region)	0.000	0.999	0.001
M40.04 Postural kyphosis (Thoracic region)	0.000	0.999	0.001
M40.03 Postural kyphosis (Cervicothoracic region)	0.000	0.999	0.001
M40.02 Postural kyphosis (Cervical region)	0.000	0.999	0.001
M40.01 Postural kyphosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.00 Postural kyphosis (Multiple sites in spine)	0.000	0.999	0.001
M40.39 Flatback syndrome (Site unspecified)	0.000	0.999	0.001
M40.38 Flatback syndrome (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.37 Flatback syndrome (Lumbosacral region)	0.000	0.999	0.001
M40.36 Flatback syndrome (Lumbar region)	0.000	0.999	0.001
M40.35 Flatback syndrome (Thoracolumbar region)	0.000	0.999	0.001
M40.34 Flatback syndrome (Thoracic region)	0.000	0.999	0.001
M40.33 Flatback syndrome (Cervicothoracic region)	0.000	0.999	0.001
M40.32 Flatback syndrome (Cervical region)	0.000	0.999	0.001
M40.31 Flatback syndrome (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.30 Flatback syndrome (Multiple sites in spine)	0.000	0.999	0.001
M40.49 Other lordosis (Site unspecified)	0.000	0.999	0.001
M40.48 Other lordosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.47 Other lordosis (Lumbosacral region)	0.000	0.999	0.001
M40.46 Other lordosis (Lumbar region)	0.000	0.999	0.001
M40.45 Other lordosis (Thoracolumbar region)	0.000	0.999	0.001
M40.44 Other lordosis (Thoracic region)	0.000	0.999	0.001
M40.43 Other lordosis (Cervicothoracic region)	0.000	0.999	0.001
M40.42 Other lordosis (Cervical region)	0.000	0.999	0.001
M40.41 Other lordosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.40 Other lordosis (Multiple sites in spine)	0.000	0.999	0.001
M54.56 Low back pain (Lumbar region)	0.001	0.999	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.999	0.001
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.999	0.001
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.999	0.001
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.999	0.001
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.999	0.001
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.999	0.001
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.999	0.001
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.999	0.001
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.999	0.000
G25.4 Drug-induced chorea	0.001	0.999	0.000
G25.2 Other specified forms of tremor	0.001	0.999	0.000
G25.0 Essential tremor	0.001	0.999	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.999	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
L30 Other dermatitis	0.001	0.999	0.000
Y44 Agents primarily affecting blood constituents	0.001	0.999	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.000	0.999	0.001
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.999	0.001
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.999	0.001
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.999	0.001
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.999	0.001
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.999	0.001
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.999	0.001
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.999	0.001
M81.88 Other osteoporosis (Other)	0.000	0.999	0.001
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.86 Other osteoporosis (Lower leg)	0.000	0.999	0.001
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.84 Other osteoporosis (Hand)	0.000	0.999	0.001
M81.83 Other osteoporosis (Forearm)	0.000	0.999	0.001
M81.82 Other osteoporosis (Upper arm)	0.000	0.999	0.001
M81.81 Other osteoporosis (Shoulder region)	0.000	0.999	0.001
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.999	0.001
C79.7 Secondary malignant neoplasm of adrenal gland	0.001	0.999	0.000
M41.5 Other secondary scoliosis	0.000	0.999	0.001
O36.5 Maternal care for poor foetal growth	0.000	0.999	0.001
Y45.1 Salicylates	0.001	0.999	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.999	0.000
Y53.2 Stimulant laxatives	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M40.19 Other secondary kyphosis (Site unspecified)	0.000	0.999	0.001
M40.18 Other secondary kyphosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.17 Other secondary kyphosis (Lumbosacral region)	0.000	0.999	0.001
M40.16 Other secondary kyphosis (Lumbar region)	0.000	0.999	0.001
M40.15 Other secondary kyphosis (Thoracolumbar region)	0.000	0.999	0.001
M40.13 Other secondary kyphosis (Cervicothoracic region)	0.000	0.999	0.001
M40.12 Other secondary kyphosis (Cervical region)	0.000	0.999	0.001
M40.11 Other secondary kyphosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.10 Other secondary kyphosis (Multiple sites in spine)	0.000	0.999	0.001
M40.59 Lordosis, unspecified (Site unspecified)	0.000	0.999	0.001
M40.58 Lordosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.57 Lordosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M40.55 Lordosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M40.54 Lordosis, unspecified (Thoracic region)	0.000	0.999	0.001
M40.53 Lordosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M40.51 Lordosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.50 Lordosis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M41.49 Neuromuscular scoliosis (Site unspecified)	0.000	0.999	0.001
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.999	0.001
M81.58 Idiopathic osteoporosis (Other)	0.000	0.999	0.001
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.999	0.001
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations