TreeWAS – Variant ID: rs25832

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.919	0.081
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.922	0.078
T42.4 Benzodiazepines	0.000	0.929	0.071
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.931	0.069
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.935	0.065
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.936	0.064
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.936	0.064
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.938	0.062
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.938	0.062
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.938	0.062
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.939	0.061
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.940	0.059
T42.1 Iminostilbenes	0.000	0.942	0.057
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.943	0.057
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.944	0.056
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.944	0.056
T42.3 Barbiturates	0.000	0.944	0.056
T42.2 Succinimides and oxazolidinediones	0.000	0.944	0.056
T42.0 Hydantoin derivatives	0.000	0.946	0.054
T38.1 Thyroid hormones and substitutes	0.000	0.950	0.050
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.951	0.049
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.951	0.049
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.952	0.048
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.953	0.047
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.953	0.047
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.953	0.047
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.953	0.047
T46.7 Peripheral vasodilators	0.000	0.953	0.047
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.953	0.047
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.953	0.047
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.953	0.047
T36 Poisoning by systemic antibiotics	0.000	0.953	0.047
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.954	0.046
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.954	0.046
T47.7 Emetics	0.000	0.954	0.046
T47.6 Antidiarrhoeal drugs	0.000	0.954	0.046
T47.5 Digestants	0.000	0.954	0.046
T47.3 Saline and osmotic laxatives	0.000	0.954	0.046
T47.2 Stimulant laxatives	0.000	0.954	0.046
T47.0 Histamine H(2)-receptor antagonists	0.000	0.954	0.046
T50.8 Diagnostic agents	0.000	0.954	0.046
T50.7 Analeptics and opioid receptor antagonists	0.000	0.954	0.046
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.954	0.046
T50.5 Appetite depressants	0.000	0.954	0.046
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.954	0.046
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.954	0.046
T50.1 Loop [high-ceiling] diuretics	0.000	0.954	0.046
T50.0 Mineralocorticoids and their antagonists	0.000	0.954	0.046
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.955	0.045
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.956	0.044
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.957	0.043
T38.9 Other and unspecified hormone antagonists	0.000	0.957	0.043
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.957	0.043
T38.7 Androgens and anabolic congeners	0.000	0.957	0.043
T38.5 Other oestrogens and progestogens	0.000	0.957	0.043
T38.4 Oral contraceptives	0.000	0.957	0.043
T38.2 Antithyroid drugs	0.000	0.957	0.043
T38.0 Glucocorticoids and synthetic analogues	0.000	0.957	0.043
T47.4 Other laxatives	0.000	0.957	0.042
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.958	0.042
T50.4 Drugs affecting uric acid metabolism	0.000	0.959	0.041
T39.1 4-Aminophenol derivatives	0.000	0.959	0.041
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.960	0.039
T39.0 Salicylates	0.000	0.963	0.037
T46.1 Calcium-channel blockers	0.000	0.964	0.036
T41.5 Therapeutic gases	0.000	0.964	0.035
T41.4 Anaesthetic, unspecified	0.000	0.964	0.035
T41.3 Local anaesthetics	0.000	0.964	0.035
T41.2 Other and unspecified general anaesthetics	0.000	0.964	0.035
T41.1 Intravenous anaesthetics	0.000	0.964	0.035
T41.0 Inhaled anaesthetics	0.000	0.964	0.035
T49.9 Topical agent, unspecified	0.000	0.964	0.035
T49.8 Other topical agents	0.000	0.964	0.035
T49.7 Dental drugs, topically applied	0.000	0.964	0.035
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.964	0.035
T49.5 Ophthalmological drugs and preparations	0.000	0.964	0.035
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.964	0.035
T49.3 Emollients, demulcents and protectants	0.000	0.964	0.035
T49.2 Local astringents and local detergents	0.000	0.964	0.035
T49.1 Antipruritics	0.000	0.964	0.035
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.964	0.035
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.965	0.035
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.965	0.035
T39.4 Antirheumatics, not elsewhere classified	0.000	0.966	0.034
T39.2 Pyrazolone derivatives	0.000	0.966	0.034
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.966	0.034
T37.5 Antiviral drugs	0.000	0.966	0.034
T37.4 Anthelminthics	0.000	0.966	0.034
T37.3 Other antiprotozoal drugs	0.000	0.966	0.034
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.966	0.034
T37.1 Antimycobacterial drugs	0.000	0.966	0.034
T37.0 Sulphonamides	0.000	0.966	0.034
T36.9 Systemic antibiotic, unspecified	0.000	0.966	0.033
T36.8 Other systemic antibiotics	0.000	0.966	0.033
T36.7 Antifungal antibiotics, systemically used	0.000	0.966	0.033
T36.6 Rifamycins	0.000	0.966	0.033
T36.5 Aminoglycosides	0.000	0.966	0.033
T36.4 Tetracyclines	0.000	0.966	0.033
T36.3 Macrolides	0.000	0.966	0.033
T36.2 Chloramphenicol group	0.000	0.966	0.033
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.966	0.033
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.966	0.033
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.967	0.032
T48.4 Expectorants	0.000	0.967	0.032
T48.3 Antitussives	0.000	0.967	0.032
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.967	0.032
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.967	0.032
T48.0 Oxytocic drugs	0.000	0.967	0.032
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.968	0.032
T40.6 Other and unspecified narcotics	0.000	0.969	0.031
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.969	0.031
T36.0 Penicillins	0.000	0.969	0.031
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.969	0.031
T40.8 Lysergide [LSD]	0.000	0.969	0.031
T40.7 Cannabis (derivatives)	0.000	0.969	0.031
T40.5 Cocaine	0.000	0.969	0.031
T40.3 Methadone	0.000	0.969	0.031
T40.1 Heroin	0.000	0.969	0.031
T40.0 Opium	0.000	0.969	0.031
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.971	0.028
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.971	0.028
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.971	0.028
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.971	0.028
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.971	0.028
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.971	0.028
T44.0 Anticholinesterase agents	0.000	0.971	0.028
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.972	0.028
T40.2 Other opioids	0.000	0.972	0.028
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.973	0.027
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.973	0.027
T45.2 Vitamins, not elsewhere classified	0.000	0.973	0.027
T48.5 Anti-common-cold drugs	0.000	0.973	0.026
T40.4 Other synthetic narcotics	0.000	0.973	0.026
T45.5 Anticoagulants	0.000	0.974	0.026
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.975	0.025
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.975	0.025
T45.8 Other primarily systemic and haematological agents	0.000	0.975	0.025
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.975	0.025
T45.6 Fibrinolysis-affecting drugs	0.000	0.975	0.025
T45.4 Iron and its compounds	0.000	0.975	0.025
T45.3 Enzymes, not elsewhere classified	0.000	0.975	0.025
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.976	0.024
T43.9 Psychotropic drug, unspecified	0.000	0.977	0.022
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.977	0.022
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.977	0.022
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.977	0.023
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.979	0.021
T45.0 Antiallergic and antiemetic drugs	0.000	0.980	0.019
T43.2 Other and unspecified antidepressants	0.000	0.980	0.020
T43.6 Psychostimulants with abuse potential	0.000	0.982	0.018
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.982	0.017
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.983	0.017
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.985	0.015
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.985	0.015
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.014	0.986	0.000
C53.9 Cervix uteri, unspecified	0.014	0.986	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.013	0.987	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.013	0.987	0.000
D51 Vitamin B12 deficiency anaemia	0.013	0.987	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.011	0.989	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.011	0.989	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.990	0.010
H50.9 Strabismus, unspecified	0.010	0.990	0.000
C53 Malignant neoplasm of cervix uteri	0.010	0.990	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.010	0.990	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.010	0.990	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.009	0.990	0.000
D51.2 Transcobalamin II deficiency	0.009	0.990	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.009	0.990	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.009	0.991	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.991	0.009
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.991	0.009
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.008	0.992	0.000
I67.2 Cerebral atherosclerosis	0.008	0.992	0.000
D52.9 Folate deficiency anaemia, unspecified	0.008	0.992	0.000
C53.0 Endocervix	0.008	0.992	0.000
I71 Aortic aneurysm and dissection	0.008	0.992	0.000
R39.1 Other difficulties with micturition	0.000	0.992	0.008
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.008	0.992	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.008	0.992	0.000
X62.9 Unspecified place	0.000	0.992	0.008
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.992	0.008
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.992	0.008
O69.3 Labour and delivery complicated by short cord	0.000	0.992	0.008
D52 Folate deficiency anaemia	0.008	0.992	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.992	0.007
D50-D53 Nutritional anaemias	0.007	0.993	0.000
C53.8 Overlapping lesion of cervix uteri	0.007	0.993	0.000
C53.1 Exocervix	0.007	0.993	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.007	0.993	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.007	0.993	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
Q24 Other congenital malformations of heart	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
Q24.6 Congenital heart block	0.006	0.994	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.006	0.994	0.000
D53 Other nutritional anaemias	0.006	0.994	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.006	0.994	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.006	0.994	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.006	0.994	0.000
I71.0 Dissection of aorta [any part]	0.006	0.994	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.006	0.994	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.994	0.006
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.006	0.994	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
D52.8 Other folate deficiency anaemias	0.006	0.994	0.000
D52.1 Drug-induced folate deficiency anaemia	0.006	0.994	0.000
D52.0 Dietary folate deficiency anaemia	0.006	0.994	0.000
Q24.5 Malformation of coronary vessels	0.006	0.994	0.000
C51-C58 Malignant neoplasms of female genital organs	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
Q24.0 Dextrocardia	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.994	0.000
I85.9 Oesophageal varices without bleeding	0.006	0.994	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.006	0.994	0.000
Q21.1 Atrial septal defect	0.006	0.994	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.995	0.005
S92.30 Fracture of metatarsal bone (closed)	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
S62.5 Fracture of thumb	0.005	0.995	0.000
D53.9 Nutritional anaemia, unspecified	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
S62.51 Fracture of thumb (open)	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
S62 Fracture at wrist and hand level	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
C51 Malignant neoplasm of vulva	0.005	0.995	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
A41 Other septicaemia	0.005	0.995	0.000
S62.50 Fracture of thumb (closed)	0.005	0.995	0.000
D53.8 Other specified nutritional anaemias	0.005	0.995	0.000
D53.2 Scorbutic anaemia	0.005	0.995	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.005	0.995	0.000
D53.0 Protein deficiency anaemia	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
C56 Malignant neoplasm of ovary	0.005	0.995	0.000
S62.6 Fracture of other finger	0.005	0.995	0.000
S60-S69 Injuries to the wrist and hand	0.005	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.995	0.000
Q22.5 Ebstein's anomaly	0.004	0.995	0.000
I85.0 Oesophageal varices with bleeding	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.995	0.000
Q21.2 Atrioventricular septal defect	0.004	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.995	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.004	0.995	0.000
C51.9 Vulva, unspecified	0.004	0.995	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.004	0.996	0.000
C58 Malignant neoplasm of placenta	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
S62.1 Fracture of other carpal bone(s)	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
I85 Oesophageal varices	0.004	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
X62.0 Home	0.000	0.996	0.004
X62.8 Other specified place	0.000	0.996	0.004
X62.7 Farm	0.000	0.996	0.004
X62.6 Industrial and construction area	0.000	0.996	0.004
X62.5 Trade and service area	0.000	0.996	0.004
X62.4 Street and highway	0.000	0.996	0.004
X62.3 Sports and athletics area	0.000	0.996	0.004
X62.2 School, other institution and public administrative area	0.000	0.996	0.004
X62.1 Residential institution	0.000	0.996	0.004
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.004	0.996	0.000
S62.60 Fracture of other finger (closed)	0.004	0.996	0.000
S62.2 Fracture of first metacarpal bone	0.004	0.996	0.000
S62.61 Fracture of other finger (open)	0.004	0.996	0.000
S60 Superficial injury of wrist and hand	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.004	0.996	0.000
S69 Other and unspecified injuries of wrist and hand	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
A41.8 Other specified septicaemia	0.004	0.996	0.000
C51.8 Overlapping lesion of vulva	0.004	0.996	0.000
C51.2 Clitoris	0.004	0.996	0.000
C51.1 Labium minus	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
S67 Crushing injury of wrist and hand	0.004	0.996	0.000
A41.4 Septicaemia due to anaerobes	0.004	0.996	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.004	0.996	0.000
C51.0 Labium majus	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
C57.9 Female genital organ, unspecified	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.004	0.996	0.000
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.003	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.003	0.996	0.000
X60-X84 Intentional self-harm	0.000	0.996	0.004
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.996	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.003	0.996	0.000
C57.8 Overlapping lesion of female genital organs	0.003	0.996	0.000
C57.7 Other specified female genital organs	0.003	0.996	0.000
C57.4 Uterine adnexa, unspecified	0.003	0.996	0.000
C57.3 Parametrium	0.003	0.996	0.000
C57.2 Round ligament	0.003	0.996	0.000
C57.1 Broad ligament	0.003	0.996	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
S60.2 Contusion of other parts of wrist and hand	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
C57.0 Fallopian tube	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.003	0.997	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.003	0.997	0.000
S69.8 Other specified injuries of wrist and hand	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.003	0.997	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.000	0.997	0.003
Q35 Cleft palate	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
S60.1 Contusion of finger(s) with damage to nail	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
S69.7 Multiple injuries of wrist and hand	0.003	0.997	0.000
S62.21 Fracture of first metacarpal bone (open)	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
S60.0 Contusion of finger(s) without damage to nail	0.003	0.997	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.000	0.997	0.003
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.000	0.997	0.003
Q17.5 Prominent ear	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
S65.1 Injury of radial artery at wrist and hand level	0.003	0.997	0.000
C52 Malignant neoplasm of vagina	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
N48.8 Other specified disorders of penis	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.003	0.997	0.000
C54 Malignant neoplasm of corpus uteri	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.000	0.997	0.003
S67.0 Crushing injury of thumb and other finger(s)	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.997	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
X78 Intentional self-harm by sharp object	0.000	0.997	0.003
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.997	0.000
Q50.2 Congenital torsion of ovary	0.003	0.997	0.000
Q50.1 Developmental ovarian cyst	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
X68.9 Unspecified place	0.000	0.997	0.003
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
S63.1 Dislocation finger	0.003	0.997	0.000
S63.2 Multiple dislocations of fingers	0.003	0.997	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.003	0.997	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.003	0.997	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.003	0.997	0.000
S65.4 Injury of blood vessel(s) of thumb	0.003	0.997	0.000
S65.3 Injury of deep palmar arch	0.003	0.997	0.000
S65.2 Injury of superficial palmar arch	0.003	0.997	0.000
X67.9 Unspecified place	0.000	0.997	0.003
X84 Intentional self-harm by unspecified means	0.000	0.997	0.003
X83 Intentional self-harm by other specified means	0.000	0.997	0.003
X82 Intentional self-harm by crashing of motor vehicle	0.000	0.997	0.003
X81 Intentional self-harm by jumping or lying before moving object	0.000	0.997	0.003
X80 Intentional self-harm by jumping from a high place	0.000	0.997	0.003
X79 Intentional self-harm by blunt object	0.000	0.997	0.003
X77 Intentional self-harm by steam, hot vapours and hot objects	0.000	0.997	0.003
X76 Intentional self-harm by smoke, fire and flames	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations