TreeWAS – Variant ID: rs2589998

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C54.1 Endometrium	0.188	0.812	0.000
C54 Malignant neoplasm of corpus uteri	0.144	0.856	0.000
C51-C58 Malignant neoplasms of female genital organs	0.117	0.883	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.114	0.886	0.000
C54.8 Overlapping lesion of corpus uteri	0.103	0.897	0.000
C54.3 Fundus uteri	0.103	0.897	0.000
C54.2 Myometrium	0.103	0.897	0.000
C54.0 Isthmus uteri	0.103	0.897	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.100	0.900	0.000
C54.9 Corpus uteri, unspecified	0.095	0.905	0.000
C51 Malignant neoplasm of vulva	0.089	0.911	0.000
C58 Malignant neoplasm of placenta	0.084	0.916	0.000
C52 Malignant neoplasm of vagina	0.082	0.918	0.000
C57.0 Fallopian tube	0.080	0.920	0.000
C57.9 Female genital organ, unspecified	0.079	0.920	0.000
C57.8 Overlapping lesion of female genital organs	0.077	0.923	0.000
C51.0 Labium majus	0.075	0.925	0.000
C56 Malignant neoplasm of ovary	0.074	0.926	0.000
C57.7 Other specified female genital organs	0.072	0.928	0.000
C57.4 Uterine adnexa, unspecified	0.072	0.928	0.000
C57.3 Parametrium	0.072	0.928	0.000
C57.2 Round ligament	0.072	0.928	0.000
C57.1 Broad ligament	0.072	0.928	0.000
C51.8 Overlapping lesion of vulva	0.064	0.936	0.000
C51.2 Clitoris	0.064	0.936	0.000
C51.1 Labium minus	0.064	0.936	0.000
C53 Malignant neoplasm of cervix uteri	0.056	0.943	0.000
C51.9 Vulva, unspecified	0.056	0.944	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.953	0.047
C53.8 Overlapping lesion of cervix uteri	0.041	0.959	0.000
C53.1 Exocervix	0.041	0.959	0.000
C53.0 Endocervix	0.033	0.966	0.000
C53.9 Cervix uteri, unspecified	0.026	0.974	0.000
O72.1 Other immediate postpartum haemorrhage	0.024	0.976	0.000
O72 Postpartum haemorrhage	0.023	0.977	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.978	0.022
O72.0 Third-stage haemorrhage	0.022	0.978	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.021	0.979	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.018	0.982	0.000
O60-O75 Complications of labour and delivery	0.017	0.983	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.983	0.017
O72.3 Postpartum coagulation defects	0.016	0.983	0.000
O71 Other obstetric trauma	0.016	0.984	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.015	0.985	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.014	0.986	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.014	0.986	0.000
O71.3 Obstetric laceration of cervix	0.014	0.986	0.000
O64.1 Obstructed labour due to breech presentation	0.014	0.986	0.000
O71.8 Other specified obstetric trauma	0.013	0.986	0.000
O61 Failed induction of labour	0.013	0.986	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.014	0.986	0.000
O71.4 Obstetric high vaginal laceration alone	0.013	0.987	0.000
O64.2 Obstructed labour due to face presentation	0.013	0.987	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.013	0.987	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.013	0.987	0.000
O69.3 Labour and delivery complicated by short cord	0.013	0.987	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.013	0.987	0.000
I47.1 Supraventricular tachycardia	0.000	0.987	0.013
O69.2 Labour and delivery complicated by other cord entanglement	0.013	0.987	0.000
O73 Retained placenta and membranes, without haemorrhage	0.012	0.987	0.000
O62 Abnormalities of forces of labour	0.012	0.988	0.000
O60 Preterm delivery	0.012	0.988	0.000
O74 Complications of anaesthesia during labour and delivery	0.012	0.988	0.000
O62.2 Other uterine inertia	0.012	0.988	0.000
O71.5 Other obstetric injury to pelvic organs	0.012	0.988	0.000
O71.9 Obstetric trauma, unspecified	0.012	0.988	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.012	0.988	0.000
O71.2 Postpartum inversion of uterus	0.012	0.988	0.000
O71.1 Rupture of uterus during labour	0.012	0.988	0.000
O71.0 Rupture of uterus before onset of labour	0.012	0.988	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.012	0.988	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.011	0.988	0.000
O71.7 Obstetric haematoma of pelvis	0.011	0.988	0.000
O75.8 Other specified complications of labour and delivery	0.011	0.989	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.989	0.011
O64.5 Obstructed labour due to compound presentation	0.011	0.989	0.000
O64.4 Obstructed labour due to shoulder presentation	0.011	0.989	0.000
O64.3 Obstructed labour due to brow presentation	0.011	0.989	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.011	0.989	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.011	0.989	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.011	0.989	0.000
E55 Vitamin D deficiency	0.000	0.989	0.011
O69.8 Labour and delivery complicated by other cord complications	0.011	0.989	0.000
O61.1 Failed instrumental induction of labour	0.011	0.989	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.011	0.989	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.010	0.989	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.010	0.990	0.000
O61.0 Failed medical induction of labour	0.010	0.990	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.990	0.010
O67.9 Intrapartum haemorrhage, unspecified	0.010	0.990	0.000
G45.0 Vertebro-basilar artery syndrome	0.000	0.990	0.010
O61.9 Failed induction of labour, unspecified	0.010	0.990	0.000
O61.8 Other failed induction of labour	0.010	0.990	0.000
O75.9 Complication of labour and delivery, unspecified	0.010	0.990	0.000
O75.4 Other complications of obstetric surgery and procedures	0.010	0.990	0.000
O75.3 Other infection during labour	0.010	0.990	0.000
O75.1 Shock during or following labour and delivery	0.010	0.990	0.000
E83 Disorders of mineral metabolism	0.000	0.990	0.010
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.010	0.990	0.000
O67.8 Other intrapartum haemorrhage	0.009	0.990	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.009	0.990	0.000
O62.8 Other abnormalities of forces of labour	0.009	0.991	0.000
O60.3 Preterm delivery without spontaneous labour	0.009	0.991	0.000
O60.2 Preterm spontaneous labour with term delivery	0.009	0.991	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.009	0.991	0.000
O60.0 Preterm labour without delivery	0.009	0.991	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.009	0.991	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.009	0.991	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.009	0.991	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.009	0.991	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.009	0.991	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.009	0.991	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.009	0.991	0.000
O62.9 Abnormality of forces of labour, unspecified	0.009	0.991	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.009	0.991	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.009	0.991	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.009	0.991	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.009	0.991	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.009	0.991	0.000
O65.0 Obstructed labour due to deformed pelvis	0.009	0.991	0.000
O62.1 Secondary uterine inertia	0.009	0.991	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.991	0.009
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.008	0.991	0.000
E83.5 Disorders of calcium metabolism	0.000	0.992	0.008
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.992	0.008
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.008	0.992	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.992	0.008
E55.0 Rickets, active	0.000	0.992	0.008
E83.3 Disorders of phosphorus metabolism	0.000	0.992	0.008
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.008	0.992	0.000
O66 Other obstructed labour	0.008	0.992	0.000
O62.0 Primary inadequate contractions	0.008	0.992	0.000
O62.3 Precipitate labour	0.008	0.992	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.992	0.008
O75.0 Maternal distress during labour and delivery	0.008	0.992	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.007	0.992	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.993	0.007
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.993	0.007
E83.8 Other disorders of mineral metabolism	0.000	0.993	0.007
E83.2 Disorders of zinc metabolism	0.000	0.993	0.007
E83.0 Disorders of copper metabolism	0.000	0.993	0.007
O63 Long labour	0.007	0.993	0.000
T43.2 Other and unspecified antidepressants	0.000	0.993	0.007
E83.1 Disorders of iron metabolism	0.000	0.993	0.007
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.993	0.007
O66.2 Obstructed labour due to unusually large foetus	0.006	0.994	0.000
G45.4 Transient global amnesia	0.000	0.994	0.006
Z74.0 Reduced mobility	0.000	0.994	0.006
T43.9 Psychotropic drug, unspecified	0.000	0.994	0.006
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
S62.60 Fracture of other finger (closed)	0.000	0.994	0.006
K10.8 Other specified diseases of jaws	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
G45.3 Amaurosis fugax	0.000	0.994	0.006
O66.9 Obstructed labour, unspecified	0.006	0.994	0.000
O66.8 Other specified obstructed labour	0.006	0.994	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.006	0.994	0.000
O66.1 Obstructed labour due to locked twins	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.994	0.006
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.994	0.006
M79.69 Pain in limb (Site unspecified)	0.000	0.994	0.006
N99.3 Prolapse of vaginal vault after hysterectomy	0.006	0.994	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.005	0.994	0.000
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.005	0.995	0.000
O66.4 Failed trial of labour, unspecified	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O63.9 Long labour, unspecified	0.005	0.995	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.004	0.996	0.000
O63.1 Prolonged second stage (of labour)	0.004	0.996	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.996	0.000
O63.0 Prolonged first stage (of labour)	0.004	0.996	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.004	0.996	0.000
K25.0 Acute with haemorrhage	0.004	0.996	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.004	0.996	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I98.0 Cardiovascular syphilis	0.004	0.996	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
S62.6 Fracture of other finger	0.000	0.997	0.003
M47.89 Other spondylosis (Site unspecified)	0.000	0.997	0.003
S06.00 Concussion (without open intracranial wound)	0.003	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.003	0.997	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.003	0.997	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.997	0.003
N83.0 Follicular cyst of ovary	0.000	0.997	0.003
J95.8 Other postprocedural respiratory disorders	0.000	0.997	0.003
I47.0 Reentry ventricular arrhythmia	0.000	0.997	0.003
D10.0 Lip	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I47 Paroxysmal tachycardia	0.000	0.997	0.003
S62.2 Fracture of first metacarpal bone	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.997	0.003
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S62.51 Fracture of thumb (open)	0.000	0.997	0.003
S62 Fracture at wrist and hand level	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
T42.1 Iminostilbenes	0.000	0.997	0.003
J95.0 Tracheostomy malfunction	0.000	0.997	0.003
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
S62.5 Fracture of thumb	0.001	0.997	0.002
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.997	0.003
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.997	0.002
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.997	0.003
S62.4 Multiple fractures of metacarpal bones	0.000	0.997	0.002
S62.1 Fracture of other carpal bone(s)	0.000	0.997	0.002
T42.0 Hydantoin derivatives	0.000	0.997	0.002
D10 Benign neoplasm of mouth and pharynx	0.003	0.997	0.000
K25.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
D66 Hereditary factor VIII deficiency	0.002	0.997	0.000
D10.5 Other parts of oropharynx	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
D68.0 Von Willebrand's disease	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.002
D12.7 Rectosigmoid junction	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.000	0.998	0.002
E51 Thiamine deficiency	0.000	0.998	0.002
E50 Vitamin A deficiency	0.000	0.998	0.002
E60 Dietary zinc deficiency	0.000	0.998	0.002
E59 Dietary selenium deficiency	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.000	0.998	0.002
E52 Niacin deficiency [pellagra]	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.002
S06.0 Concussion	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.000	0.998	0.002
D10.1 Tongue	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.002	0.998	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.998	0.002
D10.7 Hypopharynx	0.002	0.998	0.000
D10.6 Nasopharynx	0.002	0.998	0.000
D10.4 Tonsil	0.002	0.998	0.000
D10.2 Floor of mouth	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
J04.0 Acute laryngitis	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z74.3 Need for continuous supervision	0.000	0.998	0.002
Z93.5 Cystostomy status	0.000	0.998	0.002
E58 Dietary calcium deficiency	0.000	0.998	0.002
J95.5 Postprocedural subglottic stenosis	0.000	0.998	0.002
J95.4 Mendelson's syndrome	0.000	0.998	0.002
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.998	0.002
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.998	0.002
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.002	0.998	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
K25 Gastric ulcer	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.002
E61.6 Vanadium deficiency	0.000	0.998	0.002
E61.5 Molybdenum deficiency	0.000	0.998	0.002
E61.4 Chromium deficiency	0.000	0.998	0.002
E61.3 Manganese deficiency	0.000	0.998	0.002
E61.0 Copper deficiency	0.000	0.998	0.002
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
H27.8 Other specified disorders of lens	0.002	0.998	0.000
D10.9 Pharynx, unspecified	0.002	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.002	0.998	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
M47.8 Other spondylosis	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
O70 Perineal laceration during delivery	0.002	0.998	0.000
D37.5 Rectum	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
O20.0 Threatened abortion	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
H52.1 Myopia	0.000	0.998	0.002
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
Z74.1 Need for assistance with personal care	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
S41.1 Open wound of upper arm	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
O97 Death from sequelae of direct obstetric causes	0.002	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.998	0.000
O95 Obstetric death of unspecified cause	0.002	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
K25.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
K25.1 Acute with perforation	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.001
T36.8 Other systemic antibiotics	0.000	0.998	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
T36.6 Rifamycins	0.000	0.998	0.001
T36.5 Aminoglycosides	0.000	0.998	0.001
T36.4 Tetracyclines	0.000	0.998	0.001
T36.3 Macrolides	0.000	0.998	0.001
T36.2 Chloramphenicol group	0.000	0.998	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.001
T40.4 Other synthetic narcotics	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
L28.2 Other prurigo	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.001
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.001
D68.8 Other specified coagulation defects	0.002	0.998	0.000
O70.3 Fourth degree perineal laceration during delivery	0.001	0.998	0.000
Z71.8 Other specified counselling	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
K05 Gingivitis and periodontal diseases	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.998	0.001
S06.3 Focal brain injury	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.998	0.001
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.998	0.000
C02.4 Lingual tonsil	0.000	0.998	0.001
H20.8 Other iridocyclitis	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.001
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.998	0.000
K05.5 Other periodontal diseases	0.001	0.998	0.000
K59.9 Functional intestinal disorder, unspecified	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.001	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
N99.1 Postprocedural urethral stricture	0.001	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations