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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596460
log Bayes Factor = 22.7176
Chromosome 6   position 31,417,510  (GRCh37) Explore rs2596460 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.004 0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.007 0.993
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.011 0.989
E10.9 Without complications
0.000 0.013 0.987
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.014 0.986
Chapter I Certain infectious and parasitic diseases
0.000 0.020 0.980
D50-D53 Nutritional anaemias
0.000 0.020 0.980
L57.0 Actinic keratosis
0.000 0.023 0.977
M07 Psoriatic and enteropathic arthropathies
0.000 0.023 0.977
E10.3 With ophthalmic complications
0.000 0.024 0.976
D50 Iron deficiency anaemia
0.000 0.025 0.975
D50.9 Iron deficiency anaemia, unspecified
0.000 0.028 0.972
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.028 0.972
M07.3 Other psoriatic arthropathies
0.000 0.040 0.960
B25-B34 Other viral diseases
0.000 0.048 0.952
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.051 0.949
B35-B49 Mycoses
0.000 0.056 0.944
D60-D64 Aplastic and other anaemias
0.000 0.057 0.943
C44 Other malignant neoplasms of skin
0.000 0.064 0.936
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.064 0.936
C44.3 Skin of other and unspecified parts of face
0.000 0.065 0.935
E50-E64 Other nutritional deficiencies
0.000 0.071 0.929
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.075 0.925
B37 Candidiasis
0.000 0.075 0.925
B34 Viral infection of unspecified site
0.000 0.078 0.922
D64 Other anaemias
0.000 0.079 0.921
L08 Other local infections of skin and subcutaneous tissue
0.000 0.079 0.921
C44.4 Skin of scalp and neck
0.000 0.079 0.921
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.080 0.920
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.080 0.920
L20-L30 Dermatitis and eczema
0.000 0.081 0.919
B37.8 Candidiasis of other sites
0.000 0.083 0.917
E10.1 With ketoacidosis
0.000 0.086 0.914
Chapter II Neoplasms
0.000 0.086 0.914
M06.0 Seronegative rheumatoid arthritis
0.000 0.086 0.914
E06 Thyroiditis
0.000 0.091 0.909
D64.9 Anaemia, unspecified
0.000 0.095 0.905
M20-M25 Other joint disorders
0.000 0.098 0.902
M35 Other systemic involvement of connective tissue
0.000 0.098 0.902
B34.9 Viral infection, unspecified
0.000 0.099 0.901
M35.3 Polymyalgia rheumatica
0.000 0.104 0.896
D80-D89 Certain disorders involving the immune mechanism
0.000 0.106 0.894
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.106 0.894
Chapter VIII Diseases of the ear and mastoid process
0.000 0.113 0.887
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.118 0.882
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.120 0.880
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.124 0.876
E65-E68 Obesity and other hyperalimentation
0.000 0.127 0.873
Chapter IX Diseases of the circulatory system
0.000 0.128 0.872
M45-M49 Spondylopathies
0.000 0.132 0.868
I60-I69 Cerebrovascular diseases
0.000 0.135 0.865
M05 Seropositive rheumatoid arthritis
0.000 0.137 0.863
E53 Deficiency of other B group vitamins
0.000 0.137 0.863
E10.4 With neurological complications
0.000 0.148 0.852
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.153 0.847
M45 Ankylosing spondylitis
0.000 0.157 0.843
C44.1 Skin of eyelid, including canthus
0.000 0.157 0.843
E06.3 Autoimmune thyroiditis
0.000 0.159 0.841
E14 Unspecified diabetes mellitus
0.000 0.161 0.839
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.166 0.834
D86 Sarcoidosis
0.000 0.166 0.834
C64-C68 Malignant neoplasms of urinary tract
0.000 0.168 0.832
L29 Pruritus
0.000 0.169 0.831
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.174 0.826
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.176 0.824
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.181 0.819
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.181 0.819
B35 Dermatophytosis
0.000 0.181 0.819
E53.8 Deficiency of other specified B group vitamins
0.000 0.185 0.815
M95.0 Acquired deformity of nose
0.000 0.186 0.814
L40.0 Psoriasis vulgaris
0.000 0.186 0.814
I60 Subarachnoid haemorrhage
0.000 0.187 0.813
H65-H75 Diseases of middle ear and mastoid
0.000 0.189 0.811
I63 Cerebral infarction
0.000 0.193 0.807
B99-B99 Other infectious diseases
0.000 0.194 0.806
C34 Malignant neoplasm of bronchus and lung
0.000 0.196 0.804
R47-R49 Symptoms and signs involving speech and voice
0.000 0.197 0.803
M35.0 Sicca syndrome [Sjogren]
0.000 0.199 0.801
E66 Obesity
0.000 0.203 0.797
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.203 0.797
I67 Other cerebrovascular diseases
0.000 0.208 0.792
H72 Perforation of tympanic membrane
0.000 0.209 0.791
L30 Other dermatitis
0.000 0.211 0.789
L29.0 Pruritus ani
0.000 0.212 0.788
I69 Sequelae of cerebrovascular disease
0.000 0.214 0.786
C44.7 Skin of lower limb, including hip
0.000 0.214 0.786
E10.5 With peripheral circulatory complications
0.000 0.215 0.785
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.216 0.784
E66.8 Other obesity
0.000 0.217 0.783
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.220 0.780
E10.2 With renal complications
0.000 0.227 0.773
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.227 0.773
R47 Speech disturbances, not elsewhere classified
0.000 0.230 0.770
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.000 0.231 0.769
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.231 0.769
D86.9 Sarcoidosis, unspecified
0.000 0.232 0.768
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.233 0.767
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.235 0.765
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.235 0.765
B25 Cytomegaloviral disease
0.000 0.236 0.764
C34.9 Bronchus or lung, unspecified
0.000 0.236 0.764
M00-M03 Infectious arthropathies
0.000 0.238 0.762
I67.8 Other specified cerebrovascular diseases
0.000 0.243 0.757
M60-M63 Disorders of muscles
0.000 0.243 0.757
I63.9 Cerebral infarction, unspecified
0.000 0.245 0.755
E55 Vitamin D deficiency
0.000 0.246 0.754
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.249 0.751
R41.0 Disorientation, unspecified
0.000 0.252 0.748
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.253 0.747
I05-I09 Chronic rheumatic heart diseases
0.000 0.256 0.744
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.258 0.742
M22 Disorders of patella
0.000 0.259 0.741
I20-I25 Ischaemic heart diseases
0.000 0.261 0.739
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.261 0.739
C67 Malignant neoplasm of bladder
0.000 0.261 0.739
M34 Systemic sclerosis
0.000 0.262 0.738
R47.0 Dysphasia and aphasia
0.000 0.263 0.737
M35.7 Hypermobility syndrome
0.000 0.263 0.737
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.264 0.736
D55-D59 Haemolytic anaemias
0.000 0.265 0.735
C44.2 Skin of ear and external auricular canal
0.000 0.266 0.734
H80-H83 Diseases of inner ear
0.000 0.269 0.731
R41.3 Other amnesia
0.000 0.270 0.730
B37.0 Candidal stomatitis
0.000 0.273 0.727
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.279 0.721
I21 Acute myocardial infarction
0.000 0.281 0.719
E14.9 Without complications
0.000 0.281 0.719
M46 Other inflammatory spondylopathies
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
R26 Abnormalities of gait and mobility
0.000 0.285 0.715
R91 Abnormal findings on diagnostic imaging of lung
0.000 0.285 0.715
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.288 0.712
L58 Radiodermatitis
0.000 0.288 0.712
L55 Sunburn
0.000 0.288 0.712
E70-E90 Metabolic disorders
0.000 0.290 0.710
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.291 0.709
L57.5 Actinic granuloma
0.000 0.291 0.709
L57.3 Poikiloderma of Civatte
0.000 0.291 0.709
L57.2 Cutis rhomboidalis nuchae
0.000 0.291 0.709
L57.1 Actinic reticuloid
0.000 0.291 0.709
D86.0 Sarcoidosis of lung
0.000 0.291 0.709
L04 Acute lymphadenitis
0.000 0.293 0.707
L01 Impetigo
0.000 0.293 0.707
L00 Staphylococcal scalded skin syndrome
0.000 0.293 0.707
I62 Other nontraumatic intracranial haemorrhage
0.000 0.293 0.707
I69.3 Sequelae of cerebral infarction
0.000 0.294 0.706
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.295 0.705
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.296 0.704
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.296 0.704
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.297 0.703
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.297 0.703
A75-A79 Rickettsioses
0.000 0.297 0.703
A70-A74 Other diseases caused by chlamydiae
0.000 0.297 0.703
A65-A69 Other spirochaetal diseases
0.000 0.297 0.703
A20-A28 Certain zoonotic bacterial diseases
0.000 0.297 0.703
A15-A19 Tuberculosis
0.000 0.297 0.703
R49 Voice disturbances
0.000 0.299 0.701
M07.6 Other enteropathic arthropathies
0.000 0.300 0.700
M07.5 Arthropathy in ulcerative colitis
0.000 0.300 0.700
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.300 0.700
M07.2 Psoriatic spondylitis
0.000 0.300 0.700
M07.1 Arthritis mutilans
0.000 0.300 0.700
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.300 0.700
H72.0 Central perforation of tympanic membrane
0.000 0.300 0.700
D50.1 Sideropenic dysphagia
0.000 0.301 0.699
B50-B64 Protozoal diseases
0.000 0.302 0.698
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.303 0.697
E40-E46 Malnutrition
0.000 0.303 0.697
L05 Pilonidal cyst
0.000 0.304 0.696
E13 Other specified diabetes mellitus
0.000 0.304 0.696
M14 Arthropathies in other diseases classified elsewhere
0.000 0.304 0.695
R47.1 Dysarthria and anarthria
0.000 0.308 0.692
M11 Other crystal arthropathies
0.000 0.310 0.690
L27 Dermatitis due to substances taken internally
0.000 0.310 0.689
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.311 0.689
L10-L14 Bullous disorders
0.000 0.311 0.689
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.311 0.689
B35.1 Tinea unguium
0.000 0.311 0.689
M07.38 Other psoriatic arthropathies (Other)
0.000 0.312 0.688
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.312 0.688
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.312 0.688
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.312 0.688
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.312 0.688
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.312 0.688
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.312 0.688
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.312 0.688
Chapter XXII Codes for special purposes
0.000 0.312 0.688
E03.8 Other specified hypothyroidism
0.000 0.316 0.683
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.316 0.683
A30-A49 Other bacterial diseases
0.000 0.317 0.683
B33 Other viral diseases, not elsewhere classified
0.000 0.318 0.682
B30 Viral conjunctivitis
0.000 0.318 0.682
B27 Infectious mononucleosis
0.000 0.318 0.682
B26 Mumps
0.000 0.318 0.682
L30.8 Other specified dermatitis
0.000 0.318 0.682
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.318 0.682
B99 Other and unspecified infectious diseases
0.000 0.319 0.681
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.323 0.677
B48 Other mycoses, not elsewhere classified
0.000 0.323 0.677
B47 Mycetoma
0.000 0.323 0.677
B46 Zygomycosis
0.000 0.323 0.677
B45 Cryptococcosis
0.000 0.323 0.677
B43 Chromomycosis and phaeomycotic abscess
0.000 0.323 0.677
B42 Sporotrichosis
0.000 0.323 0.677
B41 Paracoccidioidomycosis
0.000 0.323 0.677
B40 Blastomycosis
0.000 0.323 0.677
B39 Histoplasmosis
0.000 0.323 0.677
B38 Coccidioidomycosis
0.000 0.323 0.677
B36 Other superficial mycoses
0.000 0.323 0.677
R93 Abnormal findings on diagnostic imaging of other body structures
0.000 0.323 0.677
A00-A09 Intestinal infectious diseases
0.000 0.323 0.677
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.324 0.676
H60-H62 Diseases of external ear
0.000 0.326 0.674
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.328 0.672
D64.8 Other specified anaemias
0.000 0.329 0.671
C44.8 Overlapping lesion of skin
0.000 0.329 0.671
B65-B83 Helminthiases
0.000 0.331 0.668
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.332 0.668
E20-E35 Disorders of other endocrine glands
0.000 0.333 0.667
I60.8 Other subarachnoid haemorrhage
0.000 0.333 0.666
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.334 0.666
E63 Other nutritional deficiencies
0.000 0.334 0.666
E56 Other vitamin deficiencies
0.000 0.334 0.666
E51 Thiamine deficiency
0.000 0.334 0.666
E50 Vitamin A deficiency
0.000 0.334 0.666
E60 Dietary zinc deficiency
0.000 0.334 0.666
E59 Dietary selenium deficiency
0.000 0.334 0.666
E58 Dietary calcium deficiency
0.000 0.334 0.666
E54 Ascorbic acid deficiency
0.000 0.334 0.666
E52 Niacin deficiency [pellagra]
0.000 0.334 0.666
I21.9 Acute myocardial infarction, unspecified
0.000 0.334 0.666
E06.9 Thyroiditis, unspecified
0.000 0.335 0.665
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.335 0.664
B37.7 Candidal septicaemia
0.000 0.337 0.663
B37.6 Candidal endocarditis
0.000 0.337 0.663
B37.5 Candidal meningitis
0.000 0.337 0.663
B37.2 Candidiasis of skin and nail
0.000 0.337 0.663
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.000 0.338 0.662
B34.8 Other viral infections of unspecified site
0.000 0.339 0.661
B34.4 Papovirus infection, unspecified
0.000 0.339 0.661
B34.3 Parvovirus infection, unspecified
0.000 0.339 0.661
B34.2 Coronavirus infection, unspecified
0.000 0.339 0.661
B34.1 Enterovirus infection, unspecified
0.000 0.339 0.661
B34.0 Adenovirus infection, unspecified
0.000 0.339 0.661
C34.3 Lower lobe, bronchus or lung
0.000 0.339 0.661
D64.4 Congenital dyserythropoietic anaemia
0.000 0.339 0.660
D64.3 Other sideroblastic anaemias
0.000 0.339 0.660
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.339 0.660
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.339 0.660
D64.0 Hereditary sideroblastic anaemia
0.000 0.339 0.660
L08.1 Erythrasma
0.000 0.339 0.660
L08.0 Pyoderma
0.000 0.339 0.660
B35.3 Tinea pedis
0.000 0.340 0.660
A80-A89 Viral infections of the central nervous system
0.000 0.341 0.659
L24 Irritant contact dermatitis
0.000 0.341 0.659
L21 Seborrhoeic dermatitis
0.000 0.341 0.659
L26 Exfoliative dermatitis
0.000 0.341 0.659
L22 Diaper [napkin] dermatitis
0.000 0.341 0.659
M06.3 Rheumatoid nodule
0.000 0.342 0.658
E10.6 With other specified complications
0.000 0.343 0.657
I05 Rheumatic mitral valve diseases
0.000 0.344 0.656
C67.2 Lateral wall of bladder
0.000 0.345 0.655
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.345 0.655
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.345 0.655
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.345 0.655
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.345 0.655
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.345 0.655
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.345 0.655
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.345 0.655
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.348 0.652
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.348 0.652
E06.5 Other chronic thyroiditis
0.000 0.348 0.652
E06.4 Drug-induced thyroiditis
0.000 0.348 0.652
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.348 0.652
E06.1 Subacute thyroiditis
0.000 0.348 0.652
E06.0 Acute thyroiditis
0.000 0.348 0.652
E11 Non-insulin-dependent diabetes mellitus
0.000 0.350 0.650
C66 Malignant neoplasm of ureter
0.000 0.351 0.649
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.352 0.648
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.352 0.648
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.352 0.648
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.000 0.352 0.648
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.353 0.647
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.353 0.647
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.353 0.647
M32 Systemic lupus erythematosus
0.000 0.353 0.647
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.353 0.646
M35.8 Other specified systemic involvement of connective tissue
0.000 0.353 0.646
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.353 0.646
M35.5 Multifocal fibrosclerosis
0.000 0.353 0.646
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.353 0.646
M35.2 Behcet's disease
0.000 0.353 0.646
M35.1 Other overlap syndromes
0.000 0.353 0.646
D10-D36 Benign neoplasms
0.000 0.355 0.645
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.356 0.644
B37.1 Pulmonary candidiasis
0.000 0.356 0.644
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.357 0.643
D84 Other immunodeficiencies
0.000 0.359 0.641
D83 Common variable immunodeficiency
0.000 0.359 0.641
D82 Immunodeficiency associated with other major defects
0.000 0.359 0.641
D81 Combined immunodeficiencies
0.000 0.359 0.641
M99 Biomechanical lesions, not elsewhere classified
0.000 0.359 0.641
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.360 0.640
L28 Lichen simplex chronicus and prurigo
0.000 0.360 0.639
M30 Polyarteritis nodosa and related conditions
0.000 0.360 0.639
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.362 0.638
H80 Otosclerosis
0.000 0.363 0.637
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.364 0.636
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.365 0.635
L20 Atopic dermatitis
0.000 0.365 0.634
C73 Malignant neoplasm of thyroid gland
0.000 0.366 0.634
H65 Nonsuppurative otitis media
0.000 0.366 0.634
E27 Other disorders of adrenal gland
0.000 0.368 0.632
L57.4 Cutis laxa senilis
0.000 0.368 0.632
D53 Other nutritional anaemias
0.000 0.368 0.632
M06.4 Inflammatory polyarthropathy
0.000 0.368 0.632
C65 Malignant neoplasm of renal pelvis
0.000 0.368 0.632
M31 Other necrotising vasculopathies
0.000 0.368 0.632
L25 Unspecified contact dermatitis
0.000 0.369 0.631
I67.2 Cerebral atherosclerosis
0.000 0.369 0.631
R41.2 Retrograde amnesia
0.000 0.370 0.630
B25.9 Cytomegaloviral disease, unspecified
0.000 0.371 0.629
E55.9 Vitamin D deficiency, unspecified
0.000 0.371 0.629
E61 Deficiency of other nutrient elements
0.000 0.372 0.628
D80 Immunodeficiency with predominantly antibody defects
0.000 0.372 0.628
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.373 0.627
H73 Other disorders of tympanic membrane
0.000 0.373 0.627
E67 Other hyperalimentation
0.000 0.374 0.626
E68 Sequelae of hyperalimentation
0.000 0.374 0.626
D61 Other aplastic anaemias
0.000 0.374 0.626
L29.9 Pruritus, unspecified
0.000 0.374 0.626
D52 Folate deficiency anaemia
0.000 0.374 0.625
I00-I02 Acute rheumatic fever
0.000 0.375 0.625
C34.1 Upper lobe, bronchus or lung
0.000 0.375 0.625
D12.6 Colon, unspecified
0.000 0.376 0.624
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.377 0.623
D12.2 Ascending colon
0.000 0.377 0.623
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.379 0.621
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.379 0.620
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.379 0.620
M34.9 Systemic sclerosis, unspecified
0.000 0.380 0.620
M05.8 Other seropositive rheumatoid arthritis
0.000 0.381 0.619
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.381 0.619
M05.2 Rheumatoid vasculitis
0.000 0.381 0.619
M05.1 Rheumatoid lung disease
0.000 0.381 0.619
M05.0 Felty's syndrome
0.000 0.381 0.619
E53.9 Vitamin B deficiency, unspecified
0.000 0.381 0.619
E53.1 Pyridoxine deficiency
0.000 0.381 0.619
E53.0 Riboflavin deficiency
0.000 0.381 0.619
M80-M85 Disorders of bone density and structure
0.001 0.382 0.617
I08 Multiple valve diseases
0.000 0.382 0.618
R90 Abnormal findings on diagnostic imaging of central nervous system
0.000 0.383 0.617
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.384 0.616
L23 Allergic contact dermatitis
0.000 0.384 0.616
E11.3 With ophthalmic complications
0.000 0.388 0.612
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.389 0.611
M22.8 Other disorders of patella
0.000 0.389 0.611
E14.3 With ophthalmic complications
0.000 0.390 0.610
M49 Spondylopathies in diseases classified elsewhere
0.000 0.390 0.609
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.000 0.391 0.609
B15-B19 Viral hepatitis
0.000 0.391 0.609
D12.5 Sigmoid colon
0.000 0.392 0.608
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.392 0.607
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.392 0.607
M95.5 Acquired deformity of pelvis
0.000 0.392 0.607
M95.4 Acquired deformity of chest and rib
0.000 0.392 0.607
M95.3 Acquired deformity of neck
0.000 0.392 0.607
M95.2 Other acquired deformity of head
0.000 0.392 0.607
M95.1 Cauliflower ear
0.000 0.392 0.607
L50-L54 Urticaria and erythema
0.000 0.395 0.605
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.395 0.605
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.395 0.605
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.395 0.605
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.395 0.605
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.395 0.605
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.395 0.605
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.395 0.605
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.395 0.605
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.395 0.605
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.395 0.605
M62 Other disorders of muscle
0.000 0.396 0.604
L42 Pityriasis rosea
0.000 0.396 0.603
D50.8 Other iron deficiency anaemias
0.000 0.398 0.602
E14.8 With unspecified complications
0.000 0.398 0.601
E14.7 With multiple complications
0.000 0.398 0.601
E14.6 With other specified complications
0.000 0.398 0.601
E14.5 With peripheral circulatory complications
0.000 0.398 0.601
E14.4 With neurological complications
0.000 0.398 0.601
E14.2 Withrenal complications
0.000 0.398 0.601
E14.1 With ketoacidosis
0.000 0.398 0.601
E14.0 With coma
0.000 0.398 0.601
R49.0 Dysphonia
0.000 0.399 0.601
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.400 0.600
M33 Dermatopolymyositis
0.000 0.401 0.599
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.401 0.599
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.402 0.598
C31 Malignant neoplasm of accessory sinuses
0.000 0.402 0.598
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.402 0.598
C37 Malignant neoplasm of thymus
0.000 0.402 0.598
C33 Malignant neoplasm of trachea
0.000 0.402 0.598
D86.3 Sarcoidosis of skin
0.000 0.402 0.598
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.402 0.598
D86.1 Sarcoidosis of lymph nodes
0.000 0.402 0.598
H70 Mastoiditis and related conditions
0.000 0.403 0.597
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.404 0.596
L29.8 Other pruritus
0.000 0.404 0.596
L29.3 Anogenital pruritus, unspecified
0.000 0.404 0.596
L29.1 Pruritus scroti
0.000 0.404 0.596
L30.9 Dermatitis, unspecified
0.000 0.404 0.596
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.405 0.595
E05.9 Thyrotoxicosis, unspecified
0.000 0.405 0.595
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.406 0.594
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.407 0.593
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.407 0.593
M00 Pyogenic arthritis
0.000 0.408 0.592
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.408 0.592
B37.4 Candidiasis of other urogenital sites
0.000 0.408 0.591
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.409 0.590
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.409 0.590
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.410 0.590
E66.0 Obesity due to excess calories
0.000 0.410 0.590
M91-M94 Chondropathies
0.000 0.410 0.590
D62 Acute posthaemorrhagic anaemia
0.000 0.411 0.589
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.412 0.588
B35.9 Dermatophytosis, unspecified
0.000 0.413 0.587
B35.8 Other dermatophytoses
0.000 0.413 0.587
B35.6 Tinea cruris
0.000 0.413 0.587
B35.5 Tinea imbricata
0.000 0.413 0.587
B35.4 Tinea corporis
0.000 0.413 0.587
B35.2 Tinea manuum
0.000 0.413 0.587
B35.0 Tinea barbae and tinea capitis
0.000 0.413 0.587
B37.3 Candidiasis of vulva and vagina
0.000 0.413 0.586
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.414 0.586
I73 Other peripheral vascular diseases
0.000 0.414 0.586
C67.1 Dome of bladder
0.000 0.414 0.586
R26.3 Immobility
0.000 0.414 0.585
B37.9 Candidiasis, unspecified
0.000 0.415 0.584
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.417 0.583
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.417 0.583
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.417 0.583
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.417 0.583
E27.1 Primary adrenocortical insufficiency
0.000 0.417 0.583
C67.4 Posterior wall of bladder
0.000 0.417 0.583
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.417 0.582
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.418 0.582
H68 Eustachian salpingitis and obstruction
0.000 0.418 0.582
H67 Otitis media in diseases classified elsewhere
0.000 0.418 0.582
M22.3 Other derangements of patella
0.000 0.419 0.581
D51 Vitamin B12 deficiency anaemia
0.000 0.419 0.581
C34.2 Middle lobe, bronchus or lung
0.000 0.419 0.580
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.421 0.579
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.421 0.579
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.421 0.579
M80 Osteoporosis with pathological fracture
0.000 0.422 0.578
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.422 0.578

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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