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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596472
log Bayes Factor = 91.7283
Chromosome 6   position 31,428,967  (GRCh37) Explore rs2596472 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14.9 Without complications
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.003 0.997
K51.4 Pseudopolyposis of colon
0.995 0.005 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.007 0.993
G35-G37 Demyelinating diseases of the central nervous system
0.991 0.009 0.000
E14.3 With ophthalmic complications
0.000 0.010 0.990
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.016 0.984
G37 Other demyelinating diseases of central nervous system
0.981 0.019 0.000
E11.1 With ketoacidosis
0.000 0.023 0.977
E10.4 With neurological complications
0.000 0.023 0.977
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.025 0.975
G37.9 Demyelinating disease of central nervous system, unspecified
0.971 0.029 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.971 0.029 0.000
I10-I15 Hypertensive diseases
0.000 0.030 0.970
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.033 0.967
K51.2 Ulcerative (chronic) proctitis
0.964 0.036 0.000
I12 Hypertensive renal disease
0.000 0.044 0.956
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.045 0.955
M45 Ankylosing spondylitis
0.000 0.052 0.948
E11.9 Without complications
0.000 0.062 0.938
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.065 0.935
I12.0 Hypertensive renal disease with renal failure
0.000 0.075 0.925
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.077 0.923
E10.2 With renal complications
0.000 0.081 0.919
E10.8 With unspecified complications
0.000 0.082 0.918
E16.2 Hypoglycaemia, unspecified
0.000 0.096 0.904
E16 Other disorders of pancreatic internal secretion
0.000 0.100 0.900
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.103 0.897
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.106 0.894
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.109 0.891
E11.3 With ophthalmic complications
0.000 0.129 0.871
I12.9 Hypertensive renal disease without renal failure
0.000 0.134 0.866
E11.0 With coma
0.000 0.138 0.862
E10.0 With coma
0.000 0.138 0.862
K51.8 Other ulcerative colitis
0.850 0.150 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.153 0.847
E11.2 With renal complications
0.000 0.158 0.842
I15 Secondary hypertension
0.000 0.160 0.840
E10.5 With peripheral circulatory complications
0.000 0.164 0.835
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.177 0.823
K51.5 Mucosal proctocolitis
0.819 0.181 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.814 0.186 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.188 0.812
G36 Other acute disseminated demyelination
0.801 0.199 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.214 0.786
E14.6 With other specified complications
0.000 0.220 0.780
E14.4 With neurological complications
0.000 0.223 0.777
E14.8 With unspecified complications
0.000 0.238 0.762
E10.6 With other specified complications
0.000 0.245 0.755
E16.1 Other hypoglycaemia
0.000 0.253 0.747
I15.9 Seconday hypertension, unspecified
0.000 0.260 0.740
I11 Hypertensive heart disease
0.000 0.266 0.734
E11.5 With peripheral circulatory complications
0.000 0.267 0.733
E13 Other specified diabetes mellitus
0.000 0.273 0.727
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.703 0.296 0.000
G37.4 Subacute necrotising myelitis
0.703 0.296 0.000
G37.2 Central pontine myelinolysis
0.703 0.296 0.000
G37.1 Central demyelination of corpus callosum
0.703 0.296 0.000
G37.0 Diffuse sclerosis
0.703 0.296 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.299 0.701
Chapter VI Diseases of the nervous system
0.699 0.301 0.000
I13 Hypertensive heart and renal disease
0.000 0.304 0.696
E23 Hypofunction and other disorders of pituitary gland
0.000 0.307 0.693
G20-G26 Extrapyramidal and movement disorders
0.692 0.308 0.000
G20 Parkinson's disease
0.691 0.309 0.000
E11.8 With unspecified complications
0.000 0.310 0.689
E28 Ovarian dysfunction
0.000 0.314 0.686
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.320 0.680
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.320 0.680
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.320 0.680
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.320 0.680
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.320 0.680
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.320 0.680
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.320 0.680
E14.5 With peripheral circulatory complications
0.000 0.323 0.677
I15.1 Hypertension secondary to other renal disorders
0.000 0.323 0.677
G36.0 Neuromyelitis optica [Devic]
0.666 0.334 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.663 0.337 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.660 0.340 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.354 0.645
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.354 0.645
E16.4 Abnormal secretion of gastrin
0.000 0.354 0.645
E16.3 Increased secretion of glucagon
0.000 0.354 0.645
E15 Nondiabetic hypoglycaemic coma
0.000 0.359 0.641
E28.2 Polycystic ovarian syndrome
0.000 0.361 0.639
K51.0 Ulcerative (chronic) enterocolitis
0.637 0.363 0.000
E24 Cushing's syndrome
0.000 0.365 0.635
G82 Paraplegia and tetraplegia
0.633 0.367 0.000
E83.1 Disorders of iron metabolism
0.624 0.376 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.379 0.621
G82.1 Spastic paraplegia
0.617 0.383 0.000
E29 Testicular dysfunction
0.000 0.386 0.614
E22 Hyperfunction of pituitary gland
0.000 0.390 0.610
K51.1 Ulcerative (chronic) ileocolitis
0.606 0.394 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.602 0.398 0.000
I15.8 Other secondary hypertension
0.000 0.398 0.602
E11.4 With neurological complications
0.000 0.408 0.592
G21 Secondary Parkinsonism
0.576 0.423 0.000
G36.9 Acute disseminated demyelination, unspecified
0.575 0.425 0.000
G36.8 Other specified acute disseminated demyelination
0.575 0.425 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.575 0.425 0.000
I15.0 Renovascular hypertension
0.000 0.427 0.573
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.428 0.572
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.428 0.572
E40-E46 Malnutrition
0.000 0.431 0.569
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.437 0.563
E32 Diseases of thymus
0.000 0.437 0.563
E31 Polyglandular dysfunction
0.000 0.437 0.563
E30 Disorders of puberty, not elsewhere classified
0.000 0.437 0.563
E25 Adrenogenital disorders
0.000 0.437 0.563
E23.6 Other disorders of pituitary gland
0.000 0.441 0.559
I15.2 Hypertension secondary to endocrine disorders
0.000 0.451 0.549
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.463 0.536
E23.2 Diabetes insipidus
0.000 0.465 0.535
E13.9 Without complications
0.000 0.469 0.531
G11 Hereditary ataxia
0.527 0.473 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.473 0.527
E26 Hyperaldosteronism
0.000 0.475 0.525
E13.8 With unspecified complications
0.000 0.479 0.521
E13.7 With multiple complications
0.000 0.479 0.521
E13.6 With other specified complications
0.000 0.479 0.521
E13.5 With peripheral circulatory complications
0.000 0.479 0.521
E13.4 With neurological complications
0.000 0.479 0.521
E13.3 With ophthalmic complications
0.000 0.479 0.521
E13.2 With renal complications
0.000 0.479 0.521
E13.1 With ketoacidosis
0.000 0.479 0.521
E13.0 With coma
0.000 0.479 0.521
G81 Hemiplegia
0.520 0.480 0.000
G10 Huntington's disease
0.518 0.482 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G23 Other degenerative diseases of basal ganglia
0.507 0.493 0.000
E34 Other endocrine disorders
0.000 0.496 0.504
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.501 0.499
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.501 0.499
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.501 0.499
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.501 0.499
E24.9 Cushing's syndrome, unspecified
0.000 0.501 0.499
M06 Other rheumatoid arthritis
0.000 0.501 0.499
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.503 0.497
E23.1 Drug-induced hypopituitarism
0.000 0.503 0.497
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.496 0.504 0.000
G22 Parkinsonism in diseases classified elsewhere
0.496 0.504 0.000
G80 Infantile cerebral palsy
0.494 0.506 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.492 0.507 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.508 0.492
E28.8 Other ovarian dysfunction
0.000 0.508 0.492
E28.1 Androgen excess
0.000 0.508 0.492
E28.0 Oestrogen excess
0.000 0.508 0.492
E24.0 Pituitary-dependent Cushing's disease
0.000 0.508 0.492
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.509 0.491
E29.1 Testicular hypofunction
0.000 0.509 0.491
G30-G32 Other degenerative diseases of the nervous system
0.478 0.522 0.000
E22.1 Hyperprolactinaemia
0.000 0.522 0.477
G82.5 Tetraplegia, unspecified
0.476 0.524 0.000
G82.2 Paraplegia, unspecified
0.471 0.529 0.000
G21.0 Malignant neuroleptic syndrome
0.462 0.537 0.000
G11.9 Hereditary ataxia, unspecified
0.461 0.539 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.458 0.542 0.000
E20 Hypoparathyroidism
0.000 0.545 0.455
M06.3 Rheumatoid nodule
0.000 0.545 0.455
E24.8 Other Cushing's syndrome
0.000 0.545 0.455
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.545 0.455
E24.3 Ectopic ACTH syndrome
0.000 0.545 0.455
E24.2 Drug-induced Cushing's syndrome
0.000 0.545 0.455
E24.1 Nelson's syndrome
0.000 0.545 0.455
G82.3 Flaccid tetraplegia
0.454 0.546 0.000
G82.0 Flaccid paraplegia
0.454 0.546 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.559 0.440
E29.8 Other testicular dysfunction
0.000 0.559 0.440
E29.0 Testicular hyperfunction
0.000 0.559 0.440
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.563 0.437
E22.8 Other hyperfunction of pituitary gland
0.000 0.563 0.437
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.432 0.568 0.000
G81.9 Hemiplegia, unspecified
0.430 0.570 0.000
G14 Postpolio syndrome
0.428 0.572 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.575 0.425
G83 Other paralytic syndromes
0.425 0.575 0.000
G25 Other extrapyramidal and movement disorders
0.417 0.583 0.000
G21.9 Secondary Parkinsonism, unspecified
0.413 0.586 0.000
G21.8 Other secondary Parkinsonism
0.413 0.586 0.000
G21.4 Vascular parkinsonism
0.413 0.586 0.000
G21.3 Postencephalitic Parkinsonism
0.413 0.586 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.413 0.586 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.590 0.410
E21.4 Other specified disorders of parathyroid gland
0.000 0.590 0.410
E21.2 Other hyperparathyroidism
0.000 0.590 0.410
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.592 0.408
E45 Retarded development following protein-energy malnutrition
0.000 0.592 0.408
E43 Unspecified severe protein-energy malnutrition
0.000 0.592 0.408
E42 Marasmic kwashiorkor
0.000 0.592 0.408
E41 Nutritional marasmus
0.000 0.592 0.408
E40 Kwashiorkor
0.000 0.592 0.408
M06.34 Rheumatoid nodule (Hand)
0.000 0.594 0.406
G11.4 Hereditary spastic paraplegia
0.406 0.594 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.596 0.404
E25.8 Other adrenogenital disorders
0.000 0.596 0.404
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.596 0.404
E30.9 Disorder of puberty, unspecified
0.000 0.596 0.404
E30.8 Other disorders of puberty
0.000 0.596 0.404
E30.1 Precocious puberty
0.000 0.596 0.404
E30.0 Delayed puberty
0.000 0.596 0.404
E31.9 Polyglandular dysfunction, unspecified
0.000 0.596 0.404
E31.8 Other polyglandular dysfunction
0.000 0.596 0.404
E31.1 Polyglandular hyperfunction
0.000 0.596 0.404
E31.0 Autoimmune polyglandular failure
0.000 0.596 0.404
E32.9 Disease of thymus, unspecified
0.000 0.596 0.404
E32.8 Other diseases of thymus
0.000 0.596 0.404
E32.1 Abscess of thymus
0.000 0.596 0.404
E32.0 Persistent hyperplasia of thymus
0.000 0.596 0.404
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.596 0.404
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.596 0.404
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.596 0.404
E11.6 With other specified complications
0.001 0.600 0.399
G40-G47 Episodic and paroxysmal disorders
0.398 0.602 0.000
G47 Sleep disorders
0.388 0.612 0.000
E28.3 Primary ovarian failure
0.000 0.612 0.387
G80.2 Infantile hemiplegia
0.383 0.616 0.000
G80.8 Other infantile cerebral palsy
0.381 0.618 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.380 0.620 0.000
G80.9 Infantile cerebral palsy, unspecified
0.379 0.621 0.000
G11.1 Early-onset cerebellar ataxia
0.379 0.621 0.000
G11.8 Other hereditary ataxias
0.378 0.622 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.378 0.622 0.000
G11.2 Late-onset cerebellar ataxia
0.378 0.622 0.000
G11.0 Congenital nonprogressive ataxia
0.378 0.622 0.000
E26.8 Other hyperaldosteronism
0.000 0.623 0.376
E26.1 Secondary hyperaldosteronism
0.000 0.623 0.376
G23.8 Other specified degenerative diseases of basal ganglia
0.375 0.625 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.626 0.374
G81.0 Flaccid hemiplegia
0.373 0.627 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.628 0.372
E22.0 Acromegaly and pituitary gigantism
0.000 0.629 0.371
E23.0 Hypopituitarism
0.000 0.631 0.369
G04 Encephalitis, myelitis and encephalomyelitis
0.368 0.632 0.000
E34.0 Carcinoid syndrome
0.000 0.633 0.367
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.366 0.634 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.364 0.636 0.000
G23.3 Multiple system atrophy, cerebellar type
0.364 0.636 0.000
G23.2 Striatonigral degeneration
0.364 0.636 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.364 0.636 0.000
G23.0 Hallervorden-Spatz disease
0.364 0.636 0.000
E34.5 Androgen resistance syndrome
0.000 0.638 0.361
E34.4 Constitutional tall stature
0.000 0.638 0.361
E34.3 Short stature, not elsewhere classified
0.000 0.638 0.361
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.638 0.361
E34.1 Other hypersecretion of intestinal hormones
0.000 0.638 0.361
M06.8 Other specified rheumatoid arthritis
0.000 0.642 0.358
M06.2 Rheumatoid bursitis
0.000 0.642 0.358
M06.1 Adult-onset Still's disease
0.000 0.642 0.358
G47.9 Sleep disorder, unspecified
0.357 0.643 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.644 0.356
G03 Meningitis due to other and unspecified causes
0.356 0.644 0.000
G80.4 Ataxic cerebral palsy
0.355 0.645 0.000
G80.3 Dyskinetic cerebral palsy
0.355 0.645 0.000
E34.8 Other specified endocrine disorders
0.000 0.646 0.353
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.353 0.647 0.000
G81.1 Spastic hemiplegia
0.353 0.647 0.000
G83.4 Cauda equina syndrome
0.349 0.651 0.000
E50-E64 Other nutritional deficiencies
0.000 0.652 0.348
G82.4 Spastic tetraplegia
0.346 0.653 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.346 0.654 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.344 0.655 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.344 0.656 0.000
E26.0 Primary hyperaldosteronism
0.000 0.656 0.344
K90 Intestinal malabsorption
0.000 0.657 0.343
G25.3 Myoclonus
0.343 0.657 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.343 0.657 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.342 0.658 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.662 0.338
G30 Alzheimer's disease
0.337 0.662 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.664 0.336
G80.0 Spastic cerebral palsy
0.334 0.665 0.000
G47.4 Narcolepsy and cataplexy
0.333 0.667 0.000
E20.8 Other hypoparathyroidism
0.000 0.673 0.326
E20.1 Pseudohypoparathyroidism
0.000 0.673 0.326
E20.0 Idiopathic hypoparathyroidism
0.000 0.673 0.326
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.673 0.326
M06.38 Rheumatoid nodule (Other)
0.000 0.673 0.326
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.673 0.326
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.673 0.326
M06.33 Rheumatoid nodule (Forearm)
0.000 0.673 0.326
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.673 0.326
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.673 0.326
E27 Other disorders of adrenal gland
0.000 0.674 0.326
G47.8 Other sleep disorders
0.326 0.674 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.674 0.326
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.325 0.675 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.320 0.680 0.000
G25.2 Other specified forms of tremor
0.316 0.684 0.000
G00 Bacterial meningitis, not elsewhere classified
0.313 0.686 0.000
E65 Localised adiposity
0.000 0.688 0.312
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.310 0.690 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.310 0.690 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.310 0.690 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.310 0.690 0.000
G25.1 Drug-induced tremor
0.309 0.691 0.000
J45 Asthma
0.001 0.693 0.307
G24 Dystonia
0.307 0.693 0.001
E34.9 Endocrine disorder, unspecified
0.000 0.694 0.306
G25.9 Extrapyramidal and movement disorder, unspecified
0.305 0.694 0.000
E67 Other hyperalimentation
0.000 0.695 0.305
E68 Sequelae of hyperalimentation
0.000 0.695 0.305
G83.5 Locked-in syndrome
0.305 0.695 0.000
G83.3 Monoplegia, unspecified
0.305 0.695 0.000
G83.0 Diplegia of upper limbs
0.305 0.695 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.302 0.698 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.300 0.700 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.299 0.701 0.000
G25.5 Other chorea
0.299 0.701 0.000
G25.4 Drug-induced chorea
0.299 0.701 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.299 0.701 0.000
G80.1 Spastic diplegia
0.294 0.705 0.000
G83.1 Monoplegia of lower limb
0.293 0.707 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.707 0.293
E44.0 Moderate protein-energy malnutrition
0.000 0.707 0.293
G90-G99 Other disorders of the nervous system
0.293 0.707 0.000
G12 Spinal muscular atrophy and related syndromes
0.291 0.708 0.001
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.291 0.709 0.000
G47.2 Disorders of the sleep-wake schedule
0.289 0.711 0.000
G70-G73 Diseases of myoneural junction and muscle
0.282 0.717 0.000
G83.8 Other specified paralytic syndromes
0.281 0.719 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.280 0.720 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.273 0.727 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.273 0.727 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.273 0.727 0.000
G30.0 Alzheimer's disease with early onset
0.272 0.728 0.000
G83.2 Monoplegia of upper limb
0.269 0.730 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.732 0.268
G06.0 Intracranial abscess and granuloma
0.268 0.732 0.000
G83.9 Paralytic syndrome, unspecified
0.266 0.734 0.000
G43 Migraine
0.264 0.736 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.264 0.736 0.000
G04.1 Tropical spastic paraplegia
0.264 0.736 0.000
G04.0 Acute disseminated encephalitis
0.264 0.736 0.000
E51 Thiamine deficiency
0.000 0.738 0.262
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.262 0.738 0.000
G03.9 Meningitis, unspecified
0.258 0.742 0.000
E58 Dietary calcium deficiency
0.000 0.743 0.257
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.743 0.256
M06.18 Adult-onset Still's disease (Other)
0.000 0.743 0.256
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.743 0.256
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.743 0.256
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.743 0.256
M06.14 Adult-onset Still's disease (Hand)
0.000 0.743 0.256
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.743 0.256
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.743 0.256
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.743 0.256
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.743 0.256
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.743 0.256
M06.28 Rheumatoid bursitis (Other)
0.000 0.743 0.256
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.743 0.256
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.743 0.256
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.743 0.256
M06.24 Rheumatoid bursitis (Hand)
0.000 0.743 0.256
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.743 0.256
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.743 0.256
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.743 0.256
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.743 0.256
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.743 0.256
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.743 0.256
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.743 0.256
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.743 0.256
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.743 0.256
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.743 0.256
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.743 0.256
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.743 0.256
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.743 0.256
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.743 0.256
E83 Disorders of mineral metabolism
0.255 0.744 0.001
G03.8 Meningitis due to other specified causes
0.255 0.745 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.255 0.745 0.000
G03.1 Chronic meningitis
0.255 0.745 0.000
G03.0 Nonpyogenic meningitis
0.255 0.745 0.000
G06.2 Extradural and subdural abscess, unspecified
0.252 0.748 0.000
G30.8 Other Alzheimer's disease
0.252 0.748 0.000
G90 Disorders of autonomic nervous system
0.251 0.749 0.000
G47.3 Sleep apnoea
0.251 0.749 0.000
G41 Status epilepticus
0.250 0.750 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.750 0.249
E63 Other nutritional deficiencies
0.000 0.750 0.249
E50 Vitamin A deficiency
0.000 0.750 0.249
E60 Dietary zinc deficiency
0.000 0.750 0.249
E59 Dietary selenium deficiency
0.000 0.750 0.249
E54 Ascorbic acid deficiency
0.000 0.750 0.249
E52 Niacin deficiency [pellagra]
0.000 0.750 0.249
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.248 0.752 0.000
G02.1 Meningitis in mycoses
0.248 0.752 0.000
G31.2 Degeneration of nervous system due to alcohol
0.246 0.753 0.000
K90.8 Other intestinal malabsorption
0.000 0.754 0.246
K90.3 Pancreatic steatorrhoea
0.000 0.754 0.246
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.754 0.246
K90.1 Tropical sprue
0.000 0.754 0.246
G31.1 Senile degeneration of brain, not elsewhere classified
0.246 0.754 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.755 0.245
G02.0 Meningitis in viral diseases classified elsewhere
0.241 0.759 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.759 0.241
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.759 0.241
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.759 0.241
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.759 0.241
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.759 0.241
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.759 0.241
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.759 0.241
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.759 0.241
K90.9 Intestinal malabsorption, unspecified
0.000 0.759 0.240
E61 Deficiency of other nutrient elements
0.000 0.762 0.238
E00-E07 Disorders of thyroid gland
0.000 0.764 0.236
G93 Other disorders of brain
0.235 0.765 0.000
G46.7 Other lacunar syndromes
0.234 0.766 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.766 0.234
E27.0 Other adrenocortical overactivity
0.000 0.766 0.234
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.233 0.766 0.000
E56 Other vitamin deficiencies
0.000 0.769 0.231
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.770 0.230
G25.8 Other specified extrapyramidal and movement disorders
0.227 0.773 0.000
G96 Other disorders of central nervous system
0.225 0.774 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.775 0.225
G00.8 Other bacterial meningitis
0.225 0.775 0.000
G00.3 Staphylococcal meningitis
0.225 0.775 0.000
G00.2 Streptococcal meningitis
0.225 0.775 0.000
G00.0 Haemophilus meningitis
0.225 0.775 0.000
G24.8 Other dystonia
0.223 0.776 0.000
J45.8 Mixed asthma
0.001 0.778 0.221
J45.1 Nonallergic asthma
0.001 0.779 0.220
G24.4 Idiopathic orofacial dystonia
0.220 0.779 0.001
G24.2 Idiopathic nonfamilial dystonia
0.220 0.779 0.001
G24.1 Idiopathic familial dystonia
0.220 0.779 0.001
G24.0 Drug-induced dystonia
0.220 0.779 0.001
G00.9 Bacterial meningitis, unspecified
0.220 0.780 0.000
G30.1 Alzheimer's disease with late onset
0.219 0.781 0.000
E67.8 Other specified hyperalimentation
0.000 0.781 0.219
E67.3 Hypervitaminosis D
0.000 0.781 0.219
E67.2 Megavitamin-B6 syndrome
0.000 0.781 0.219
E67.1 Hypercarotenaemia
0.000 0.781 0.219
E67.0 Hypervitaminosis A
0.000 0.781 0.219
E20.9 Hypoparathyroidism, unspecified
0.001 0.781 0.218
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.781 0.219
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.217 0.783 0.000
G46.6 Pure sensory lacunar syndrome
0.217 0.783 0.000
G46.5 Pure motor lacunar syndrome
0.217 0.783 0.000
G46.3 Brain stem stroke syndrome
0.217 0.783 0.000
G46.2 Posterior cerebral artery syndrome
0.217 0.783 0.000
G46.1 Anterior cerebral artery syndrome
0.217 0.783 0.000
G46.0 Middle cerebral artery syndrome
0.217 0.783 0.000
G46.4 Cerebellar stroke syndrome
0.217 0.783 0.000
G24.9 Dystonia, unspecified
0.216 0.783 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.216 0.784 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.786 0.214
G43.8 Other migraine
0.214 0.786 0.000
G93.4 Encephalopathy, unspecified
0.211 0.789 0.000
E83.3 Disorders of phosphorus metabolism
0.210 0.790 0.000
G92 Toxic encephalopathy
0.210 0.790 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.210 0.790 0.000
G12.9 Spinal muscular atrophy, unspecified
0.209 0.790 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.209 0.790 0.001
G12.1 Other inherited spinal muscular atrophy
0.209 0.790 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.209 0.790 0.001
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.792 0.208
G98 Other disorders of nervous system, not elsewhere classified
0.208 0.792 0.000
G30.9 Alzheimer's disease, unspecified
0.206 0.794 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.795 0.205
G06.1 Intraspinal abscess and granuloma
0.203 0.797 0.000
G93.8 Other specified disorders of brain
0.203 0.797 0.000
G43.0 Migraine without aura [common migraine]
0.203 0.797 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.203 0.797 0.000
E51.2 Wernicke's encephalopathy
0.000 0.799 0.201
G90.0 Idiopathic peripheral autonomic neuropathy
0.200 0.800 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.801 0.199
G24.3 Spasmodic torticollis
0.197 0.802 0.001
E83.5 Disorders of calcium metabolism
0.195 0.805 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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