TreeWAS – Variant ID: rs2596501

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.000	1.000
R31 Unspecified haematuria	0.999	0.001	0.000
E50-E64 Other nutritional deficiencies	0.000	0.001	0.999
D86 Sarcoidosis	0.000	0.001	0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.001	0.999
H36.0 Diabetic retinopathy	0.000	0.002	0.998
D86.9 Sarcoidosis, unspecified	0.000	0.002	0.998
E14 Unspecified diabetes mellitus	0.000	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.002	0.998
E11 Non-insulin-dependent diabetes mellitus	0.000	0.002	0.998
D80-D89 Certain disorders involving the immune mechanism	0.000	0.002	0.998
E16 Other disorders of pancreatic internal secretion	0.000	0.002	0.998
E11.3 With ophthalmic complications	0.000	0.002	0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.002	0.998
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.002	0.998
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.003	0.997
E53 Deficiency of other B group vitamins	0.000	0.003	0.997
E16.2 Hypoglycaemia, unspecified	0.000	0.003	0.997
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
E53.8 Deficiency of other specified B group vitamins	0.000	0.005	0.995
M45 Ankylosing spondylitis	0.000	0.007	0.993
E14.3 With ophthalmic complications	0.000	0.012	0.988
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.019	0.981
E05.9 Thyrotoxicosis, unspecified	0.000	0.029	0.971
E10.2 With renal complications	0.000	0.032	0.968
E27.1 Primary adrenocortical insufficiency	0.000	0.045	0.955
E65-E68 Obesity and other hyperalimentation	0.000	0.046	0.954
D86.1 Sarcoidosis of lymph nodes	0.000	0.047	0.953
E10.4 With neurological complications	0.000	0.049	0.951
L40 Psoriasis	0.000	0.053	0.947
E27 Other disorders of adrenal gland	0.000	0.054	0.946
L40.5 Arthropathic psoriasis	0.000	0.055	0.945
D50-D53 Nutritional anaemias	0.000	0.056	0.944
E20-E35 Disorders of other endocrine glands	0.000	0.057	0.943
L40.9 Psoriasis, unspecified	0.000	0.058	0.942
E10.5 With peripheral circulatory complications	0.000	0.064	0.936
E55 Vitamin D deficiency	0.000	0.067	0.933
E66 Obesity	0.000	0.070	0.930
E66.8 Other obesity	0.000	0.077	0.923
D60-D64 Aplastic and other anaemias	0.000	0.080	0.920
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.081	0.919
D50 Iron deficiency anaemia	0.000	0.082	0.918
D50.9 Iron deficiency anaemia, unspecified	0.000	0.086	0.914
K90 Intestinal malabsorption	0.000	0.091	0.909
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.096	0.904
G35 Multiple sclerosis	0.000	0.101	0.899
E11.1 With ketoacidosis	0.000	0.110	0.890
E14.9 Without complications	0.000	0.111	0.889
D61 Other aplastic anaemias	0.000	0.113	0.887
E55.9 Vitamin D deficiency, unspecified	0.000	0.114	0.886
D55-D59 Haemolytic anaemias	0.000	0.118	0.882
E10.0 With coma	0.000	0.125	0.875
D86.3 Sarcoidosis of skin	0.000	0.134	0.866
L40-L45 Papulosquamous disorders	0.000	0.138	0.862
D59 Acquired haemolytic anaemia	0.000	0.141	0.859
# Top node	0.000	0.144	0.856
D69 Purpura and other haemorrhagic conditions	0.000	0.147	0.853
D61.9 Aplastic anaemia, unspecified	0.000	0.149	0.851
K90-K93 Other diseases of the digestive system	0.000	0.149	0.851
E10.8 With unspecified complications	0.000	0.151	0.849
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.153	0.847
M45-M49 Spondylopathies	0.000	0.155	0.845
E10.6 With other specified complications	0.000	0.156	0.844
D72 Other disorders of white blood cells	0.000	0.160	0.840
D75 Other diseases of blood and blood-forming organs	0.000	0.167	0.833
D86.0 Sarcoidosis of lung	0.000	0.169	0.831
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.169	0.831
Chapter VI Diseases of the nervous system	0.000	0.171	0.829
Chapter XI Diseases of the digestive system	0.000	0.173	0.827
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.173	0.827
H36 Retinal disorders in diseases classified elsewhere	0.000	0.176	0.824
M07.3 Other psoriatic arthropathies	0.000	0.181	0.819
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.181	0.819
K70-K77 Diseases of liver	0.000	0.182	0.818
M05-M14 Inflammatory polyarthropathies	0.000	0.183	0.817
M07 Psoriatic and enteropathic arthropathies	0.000	0.183	0.817
E14.8 With unspecified complications	0.000	0.190	0.810
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.191	0.809
E53.9 Vitamin B deficiency, unspecified	0.000	0.192	0.808
E27.2 Addisonian crisis	0.000	0.193	0.807
D66 Hereditary factor VIII deficiency	0.000	0.195	0.805
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.197	0.803
E51 Thiamine deficiency	0.000	0.198	0.802
E14.2 Withrenal complications	0.000	0.201	0.799
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.203	0.797
D72.8 Other specified disorders of white blood cells	0.000	0.203	0.797
E20 Hypoparathyroidism	0.000	0.205	0.795
D59.1 Other autoimmune haemolytic anaemias	0.000	0.209	0.791
E11.8 With unspecified complications	0.000	0.214	0.786
D64 Other anaemias	0.000	0.214	0.786
E14.1 With ketoacidosis	0.000	0.216	0.784
K75 Other inflammatory liver diseases	0.000	0.222	0.778
K76 Other diseases of liver	0.000	0.222	0.778
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.223	0.777
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.223	0.777
L40.1 Generalised pustular psoriasis	0.000	0.225	0.775
E66.0 Obesity due to excess calories	0.000	0.226	0.774
E14.6 With other specified complications	0.000	0.236	0.764
L40.3 Pustulosis palmaris et plantaris	0.000	0.238	0.762
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.239	0.761
D84 Other immunodeficiencies	0.000	0.240	0.760
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.249	0.751
D69.2 Other nonthrombocytopenic purpura	0.000	0.250	0.750
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.253	0.747
K75.8 Other specified inflammatory liver diseases	0.000	0.257	0.743
K76.8 Other specified diseases of liver	0.000	0.260	0.740
K75.4 Autoimmune hepatitis	0.000	0.261	0.739
D61.1 Drug-induced aplastic anaemia	0.000	0.263	0.737
K76.6 Portal hypertension	0.000	0.265	0.735
D69.6 Thrombocytopenia, unspecified	0.000	0.266	0.734
D64.9 Anaemia, unspecified	0.000	0.268	0.732
K73 Chronic hepatitis, not elsewhere classified	0.000	0.273	0.727
G62 Other polyneuropathies	0.000	0.273	0.727
L40.0 Psoriasis vulgaris	0.000	0.274	0.726
D51 Vitamin B12 deficiency anaemia	0.000	0.274	0.726
G62.9 Polyneuropathy, unspecified	0.000	0.277	0.723
M12 Other specific arthropathies	0.000	0.279	0.721
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.279	0.721
L40.4 Guttate psoriasis	0.000	0.279	0.721
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.279	0.721
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.279	0.721
D75.0 Familial erythrocytosis	0.000	0.280	0.720
K90.8 Other intestinal malabsorption	0.000	0.280	0.720
E10.7 With multiple complications	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.284	0.716
E63 Other nutritional deficiencies	0.000	0.284	0.716
E50 Vitamin A deficiency	0.000	0.284	0.716
E60 Dietary zinc deficiency	0.000	0.284	0.716
E59 Dietary selenium deficiency	0.000	0.284	0.716
E52 Niacin deficiency [pellagra]	0.000	0.284	0.716
E15 Nondiabetic hypoglycaemic coma	0.000	0.284	0.716
E14.7 With multiple complications	0.000	0.284	0.715
E14.0 With coma	0.000	0.284	0.715
E05.5 Thyroid crisis or storm	0.000	0.284	0.715
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.715
E11.7 With multiple complications	0.000	0.284	0.715
D81 Combined immunodeficiencies	0.000	0.285	0.715
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.285	0.715
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.285	0.715
E16.4 Abnormal secretion of gastrin	0.000	0.285	0.715
E16.3 Increased secretion of glucagon	0.000	0.285	0.715
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.285	0.715
E53.1 Pyridoxine deficiency	0.000	0.285	0.715
E53.0 Riboflavin deficiency	0.000	0.285	0.715
E54 Ascorbic acid deficiency	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.714
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.288	0.712
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.288	0.712
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.288	0.712
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.288	0.712
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.288	0.712
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.288	0.712
E05.8 Other thyrotoxicosis	0.000	0.292	0.708
E11.5 With peripheral circulatory complications	0.000	0.293	0.707
D82 Immunodeficiency associated with other major defects	0.000	0.296	0.704
E25 Adrenogenital disorders	0.000	0.298	0.702
H30-H36 Disorders of choroid and retina	0.000	0.301	0.699
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.310	0.690
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.311	0.689
E20.9 Hypoparathyroidism, unspecified	0.000	0.311	0.689
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.313	0.687
G30-G32 Other degenerative diseases of the nervous system	0.000	0.313	0.687
E56 Other vitamin deficiencies	0.000	0.313	0.686
E11.2 With renal complications	0.000	0.315	0.685
E67 Other hyperalimentation	0.000	0.316	0.684
E68 Sequelae of hyperalimentation	0.000	0.316	0.684
E14.5 With peripheral circulatory complications	0.000	0.316	0.684
E14.4 With neurological complications	0.000	0.319	0.681
L40.2 Acrodermatitis continua	0.000	0.321	0.679
E27.5 Adrenomedullary hyperfunction	0.000	0.322	0.678
E27.0 Other adrenocortical overactivity	0.000	0.322	0.678
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.324	0.676
E32 Diseases of thymus	0.000	0.324	0.676
E31 Polyglandular dysfunction	0.000	0.324	0.676
E30 Disorders of puberty, not elsewhere classified	0.000	0.324	0.676
E11.4 With neurological complications	0.000	0.324	0.676
D75.2 Essential thrombocytosis	0.000	0.325	0.675
E40-E46 Malnutrition	0.000	0.325	0.675
Chapter VII Diseases of the eye and adnexa	0.000	0.328	0.672
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.329	0.671
E55.0 Rickets, active	0.000	0.331	0.669
M00-M03 Infectious arthropathies	0.000	0.332	0.668
E66.1 Drug-induced obesity	0.000	0.333	0.667
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.337	0.663
K70 Alcoholic liver disease	0.000	0.338	0.662
D53 Other nutritional anaemias	0.000	0.338	0.662
E51.2 Wernicke's encephalopathy	0.000	0.338	0.662
D50.1 Sideropenic dysphagia	0.000	0.342	0.658
M05 Seropositive rheumatoid arthritis	0.000	0.342	0.658
K90.3 Pancreatic steatorrhoea	0.000	0.348	0.651
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.348	0.651
K90.1 Tropical sprue	0.000	0.348	0.651
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.350	0.650
D74 Methaemoglobinaemia	0.000	0.352	0.648
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.352	0.648
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.352	0.648
D83 Common variable immunodeficiency	0.000	0.354	0.646
K70.9 Alcoholic liver disease, unspecified	0.000	0.356	0.644
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.356	0.644
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.357	0.643
M14 Arthropathies in other diseases classified elsewhere	0.000	0.357	0.643
L50-L54 Urticaria and erythema	0.000	0.359	0.641
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.360	0.640
D61.8 Other specified aplastic anaemias	0.000	0.364	0.636
D61.3 Idiopathic aplastic anaemia	0.000	0.364	0.636
D61.2 Aplastic anaemia due to other external agents	0.000	0.364	0.636
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.366	0.634
K76.7 Hepatorenal syndrome	0.000	0.366	0.634
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.367	0.633
D55 Anaemia due to enzyme disorders	0.000	0.367	0.633
D69.5 Secondary thrombocytopenia	0.000	0.369	0.631
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.371	0.629
K91.3 Postoperative intestinal obstruction	0.000	0.372	0.628
M46 Other inflammatory spondylopathies	0.000	0.372	0.628
E16.1 Other hypoglycaemia	0.000	0.372	0.627
L10-L14 Bullous disorders	0.000	0.373	0.627
E24 Cushing's syndrome	0.000	0.377	0.623
H34 Retinal vascular occlusions	0.000	0.380	0.620
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.381	0.619
L44 Other papulosquamous disorders	0.000	0.382	0.618
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.382	0.618
D68 Other coagulation defects	0.000	0.382	0.618
D59.8 Other acquired haemolytic anaemias	0.000	0.384	0.616
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.384	0.616
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.384	0.616
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.384	0.616
D59.3 Haemolytic-uraemic syndrome	0.000	0.384	0.616
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.384	0.616
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.384	0.616
M12.3 Palindromic rheumatism	0.000	0.384	0.616
D69.8 Other specified haemorrhagic conditions	0.000	0.388	0.612
D69.1 Qualitative platelet defects	0.000	0.388	0.612
D61.0 Constitutional aplastic anaemia	0.000	0.389	0.611
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.389	0.611
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.390	0.610
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.391	0.608
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.393	0.607
E27.8 Other specified disorders of adrenal gland	0.000	0.394	0.606
H46 Optic neuritis	0.000	0.395	0.605
L41 Parapsoriasis	0.000	0.396	0.604
E58 Dietary calcium deficiency	0.000	0.396	0.604
M86-M90 Other osteopathies	0.000	0.396	0.604
G70-G73 Diseases of myoneural junction and muscle	0.000	0.396	0.604
D70 Agranulocytosis	0.000	0.396	0.604
D72.9 Disorder of white blood cells, unspecified	0.000	0.397	0.602
D72.0 Genetic anomalies of leukocytes	0.000	0.397	0.602
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.399	0.601
D67 Hereditary factor IX deficiency	0.000	0.400	0.600
D84.8 Other specified immunodeficiencies	0.000	0.400	0.600
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.401	0.599
E11.6 With other specified complications	0.000	0.404	0.595
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.405	0.595
M02 Reactive arthropathies	0.000	0.405	0.595
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.406	0.594
G63.2 Diabetic polyneuropathy	0.000	0.407	0.593
D69.9 Haemorrhagic condition, unspecified	0.000	0.407	0.593
E65 Localised adiposity	0.000	0.409	0.591
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.409	0.591
D72.1 Eosinophilia	0.000	0.410	0.590
M12.2 Villonodular synovitis (pigmented)	0.000	0.410	0.590
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.413	0.587
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.413	0.587
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.413	0.587
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.414	0.586
M07.5 Arthropathy in ulcerative colitis	0.000	0.414	0.586
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.414	0.586
M07.2 Psoriatic spondylitis	0.000	0.414	0.586
M07.1 Arthritis mutilans	0.000	0.414	0.586
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.414	0.586
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.416	0.584
K76.1 Chronic passive congestion of liver	0.000	0.417	0.583
K91.5 Postcholecystectomy syndrome	0.000	0.418	0.582
G36 Other acute disseminated demyelination	0.000	0.421	0.579
M10 Gout	0.000	0.421	0.579
K73.9 Chronic hepatitis, unspecified	0.000	0.421	0.579
E06 Thyroiditis	0.000	0.424	0.576
E51.9 Thiamine deficiency, unspecified	0.000	0.425	0.575
E51.8 Other manifestations of thiamine deficiency	0.000	0.425	0.575
E51.1 Beriberi	0.000	0.425	0.575
D84.1 Defects in the complement system	0.000	0.426	0.574
D89.1 Cryoglobulinaemia	0.000	0.426	0.573
M60-M63 Disorders of muscles	0.000	0.427	0.573
K77 Liver disorders in diseases classified elsewhere	0.000	0.427	0.572
D86.8 Sarcoidosis of other and combined sites	0.000	0.428	0.572
E26 Hyperaldosteronism	0.000	0.429	0.570
E20.8 Other hypoparathyroidism	0.000	0.430	0.570
E20.1 Pseudohypoparathyroidism	0.000	0.430	0.570
E20.0 Idiopathic hypoparathyroidism	0.000	0.430	0.570
D69.4 Other primary thrombocytopenia	0.000	0.432	0.568
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.432	0.568
M06 Other rheumatoid arthritis	0.000	0.433	0.567
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.435	0.565
L52 Erythema nodosum	0.000	0.436	0.564
D64.4 Congenital dyserythropoietic anaemia	0.000	0.437	0.563
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.437	0.563
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.437	0.563
D64.0 Hereditary sideroblastic anaemia	0.000	0.437	0.563
E13 Other specified diabetes mellitus	0.000	0.438	0.562
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.439	0.561
K71 Toxic liver disease	0.000	0.439	0.560
D57 Sickle-cell disorders	0.000	0.440	0.559
L43 Lichen planus	0.000	0.441	0.559
H34.8 Other retinal vascular occlusions	0.000	0.442	0.558
K75.2 Nonspecific reactive hepatitis	0.000	0.442	0.558
K75.1 Phlebitis of portal vein	0.000	0.442	0.558
K76.5 Hepatic veno-occlusive disease	0.000	0.442	0.558
K76.4 Peliosis hepatis	0.000	0.442	0.558
K76.3 Infarction of liver	0.000	0.442	0.558
K76.2 Central haemorrhagic necrosis of liver	0.000	0.442	0.558
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.443	0.556
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.444	0.556
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.446	0.554
M49 Spondylopathies in diseases classified elsewhere	0.000	0.448	0.552
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.448	0.552
L13 Other bullous disorders	0.000	0.450	0.550
M07.6 Other enteropathic arthropathies	0.000	0.450	0.550
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.450	0.550
M86 Osteomyelitis	0.000	0.451	0.549
D80 Immunodeficiency with predominantly antibody defects	0.000	0.453	0.546
G64 Other disorders of peripheral nervous system	0.000	0.454	0.546
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.455	0.545
E07 Other disorders of thyroid	0.002	0.456	0.542
H30 Chorioretinal inflammation	0.000	0.456	0.544
D64.3 Other sideroblastic anaemias	0.000	0.457	0.543
M07.38 Other psoriatic arthropathies (Other)	0.000	0.458	0.541
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.461	0.539
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.463	0.537
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.463	0.537
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.466	0.534
K72 Hepatic failure, not elsewhere classified	0.000	0.466	0.534
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.466	0.534
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.466	0.533
M87 Osteonecrosis	0.000	0.468	0.532
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.469	0.531
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.470	0.530
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.470	0.530
M08 Juvenile arthritis	0.000	0.470	0.529
E27.9 Disorder of adrenal gland, unspecified	0.000	0.471	0.529
M02.3 Reiter's disease	0.000	0.471	0.529
K65-K67 Diseases of peritoneum	0.000	0.473	0.527
M11 Other crystal arthropathies	0.000	0.473	0.527
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.478	0.521
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.478	0.521
G62.2 Polyneuropathy due to other toxic agents	0.000	0.479	0.521
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.479	0.521
D51.2 Transcobalamin II deficiency	0.000	0.479	0.521
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.479	0.521
G72 Other myopathies	0.000	0.482	0.518
M12.4 Intermittent hydrarthrosis	0.000	0.483	0.517
M12.1 Kaschin-Beck disease	0.000	0.483	0.517
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.483	0.517
D89.3 Immune reconstitution syndrome	0.000	0.483	0.517
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.484	0.516
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.485	0.515
M86.9 Osteomyelitis, unspecified	0.000	0.485	0.515
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.486	0.514
E50.9 Vitamin A deficiency, unspecified	0.000	0.486	0.513
E50.8 Other manifestations of vitamin A deficiency	0.000	0.486	0.513
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.486	0.513
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.486	0.513
E50.5 Vitamin A deficiency with night blindness	0.000	0.486	0.513
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.486	0.513
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.486	0.513
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.486	0.513
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.486	0.513
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.486	0.513
E63.9 Nutritional deficiency, unspecified	0.000	0.486	0.513
E63.8 Other specified nutritional deficiencies	0.000	0.486	0.513
E63.1 Imbalance of constituents of food intake	0.000	0.486	0.513
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.486	0.513
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.486	0.513
E64.8 Sequelae of other nutritional deficiencies	0.000	0.486	0.513
E64.3 Sequelae of rickets	0.000	0.486	0.513
E64.2 Sequelae of vitamin C deficiency	0.000	0.486	0.513
E64.1 Sequelae of vitamin A deficiency	0.000	0.486	0.513
E64.0 Sequelae of protein-energy malnutrition	0.000	0.486	0.513
E22 Hyperfunction of pituitary gland	0.000	0.487	0.513
D81.9 Combined immunodeficiency, unspecified	0.000	0.487	0.513
D81.8 Other combined immunodeficiencies	0.000	0.487	0.513
D81.7 Major histocompatibility complex class II deficiency	0.000	0.487	0.513
D81.6 Major histocompatibility complex class I deficiency	0.000	0.487	0.513
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.487	0.513
D81.4 Nezelof's syndrome	0.000	0.487	0.513
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.487	0.513
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.487	0.513
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.487	0.513
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.487	0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.487	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.487	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.487	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.487	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.487	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.487	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.487	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.487	0.512
L42 Pityriasis rosea	0.000	0.488	0.512
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.493	0.507
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.495	0.505
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.495	0.505
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.495	0.505
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.495	0.505
D82.2 Immunodeficiency with short-limbed stature	0.000	0.495	0.505
D82.0 Wiskott-Aldrich syndrome	0.000	0.495	0.505
G62.1 Alcoholic polyneuropathy	0.000	0.495	0.505
H31 Other disorders of choroid	0.000	0.496	0.504
E25.9 Adrenogenital disorder, unspecified	0.000	0.496	0.503
E25.8 Other adrenogenital disorders	0.000	0.496	0.503
M12.5 Traumatic arthropathy	0.000	0.498	0.502
L40.8 Other psoriasis	0.000	0.498	0.501
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.499	0.501
G60 Hereditary and idiopathic neuropathy	0.000	0.499	0.501
D52 Folate deficiency anaemia	0.000	0.500	0.500
H34.9 Retinal vascular occlusion, unspecified	0.000	0.501	0.499
D84.9 Immunodeficiency, unspecified	0.000	0.504	0.496
L13.0 Dermatitis herpetiformis	0.000	0.505	0.495
Chapter XXII Codes for special purposes	0.000	0.506	0.494
D82.1 Di George's syndrome	0.000	0.506	0.494
E56.9 Vitamin deficiency, unspecified	0.000	0.508	0.492
E56.8 Deficiency of other vitamins	0.000	0.508	0.492
E56.0 Deficiency of vitamin E	0.000	0.508	0.492
M46.0 Spinal enthesopathy	0.000	0.509	0.491
E67.8 Other specified hyperalimentation	0.000	0.509	0.491
E67.3 Hypervitaminosis D	0.000	0.509	0.491
E67.2 Megavitamin-B6 syndrome	0.000	0.509	0.491
E67.1 Hypercarotenaemia	0.000	0.509	0.491
E67.0 Hypervitaminosis A	0.000	0.509	0.491
P10-P15 Birth trauma	0.000	0.509	0.491
M14.2 Diabetic arthropathy	0.000	0.511	0.489
G00 Bacterial meningitis, not elsewhere classified	0.000	0.512	0.488
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.514	0.486
G03 Meningitis due to other and unspecified causes	0.000	0.515	0.485
E30.9 Disorder of puberty, unspecified	0.000	0.515	0.485
E30.8 Other disorders of puberty	0.000	0.515	0.485
E30.1 Precocious puberty	0.000	0.515	0.485
E30.0 Delayed puberty	0.000	0.515	0.485
E31.9 Polyglandular dysfunction, unspecified	0.000	0.515	0.485
E31.8 Other polyglandular dysfunction	0.000	0.515	0.485
E31.1 Polyglandular hyperfunction	0.000	0.515	0.485
E31.0 Autoimmune polyglandular failure	0.000	0.515	0.485
E32.9 Disease of thymus, unspecified	0.000	0.515	0.485
E32.8 Other diseases of thymus	0.000	0.515	0.485
E32.1 Abscess of thymus	0.000	0.515	0.485
E32.0 Persistent hyperplasia of thymus	0.000	0.515	0.485
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.515	0.485
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.515	0.485
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.515	0.485
E34 Other endocrine disorders	0.000	0.515	0.484
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.516	0.484
E45 Retarded development following protein-energy malnutrition	0.000	0.516	0.484
E43 Unspecified severe protein-energy malnutrition	0.000	0.516	0.484
E42 Marasmic kwashiorkor	0.000	0.516	0.484
E41 Nutritional marasmus	0.000	0.516	0.484
E40 Kwashiorkor	0.000	0.516	0.484
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.516	0.484
M14.6 Neuropathic arthropathy	0.000	0.516	0.484
E11.0 With coma	0.000	0.517	0.483
D68.6 Other Thrombophilia	0.000	0.517	0.483
D58 Other hereditary haemolytic anaemias	0.000	0.518	0.482
L50 Urticaria	0.000	0.518	0.482
M02.39 Reiter's disease (Site unspecified)	0.000	0.518	0.482
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.519	0.481
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.520	0.480
K90.9 Intestinal malabsorption, unspecified	0.000	0.520	0.480
K91.1 Postgastric surgery syndromes	0.000	0.521	0.479
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.000	0.521	0.479
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.000	0.521	0.479
M10.0 Idiopathic gout	0.000	0.521	0.479
G31.8 Other specified degenerative diseases of nervous system	0.000	0.523	0.477
E61 Deficiency of other nutrient elements	0.000	0.523	0.477
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.524	0.475
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.524	0.475
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.524	0.475
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.524	0.475
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.524	0.475
G63.1 Polyneuropathy in neoplastic disease	0.000	0.524	0.475
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.524	0.475
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.525	0.475
E24.0 Pituitary-dependent Cushing's disease	0.000	0.525	0.475
D53.8 Other specified nutritional anaemias	0.000	0.525	0.474
D53.2 Scorbutic anaemia	0.000	0.525	0.474
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.525	0.474

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations