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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596530
log Bayes Factor = 89.396
Chromosome 6   position 31,387,373  (GRCh37) Explore rs2596530 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
R31 Unspecified haematuria
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.001 0.999
E27 Other disorders of adrenal gland
0.000 0.005 0.995
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
I77.1 Stricture of artery
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
E10.9 Without complications
0.000 0.009 0.991
E10 Insulin-dependent diabetes mellitus
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.010 0.990
E20-E35 Disorders of other endocrine glands
0.000 0.011 0.989
I77 Other disorders of arteries and arterioles
0.000 0.014 0.986
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.021 0.979
I73 Other peripheral vascular diseases
0.000 0.027 0.973
I73.0 Raynaud's syndrome
0.000 0.042 0.958
L40.0 Psoriasis vulgaris
0.950 0.050 0.000
E10.1 With ketoacidosis
0.000 0.055 0.945
M45 Ankylosing spondylitis
0.941 0.059 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.925 0.075 0.000
E27.2 Addisonian crisis
0.000 0.095 0.905
I73.9 Peripheral vascular disease, unspecified
0.000 0.108 0.892
I77.6 Arteritis, unspecified
0.000 0.111 0.889
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.118 0.882
I74 Arterial embolism and thrombosis
0.000 0.128 0.872
L40.4 Guttate psoriasis
0.861 0.139 0.000
I72 Other aneurysm
0.000 0.158 0.842
L40.8 Other psoriasis
0.830 0.170 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.174 0.826
I71 Aortic aneurysm and dissection
0.000 0.189 0.811
E07 Other disorders of thyroid
0.000 0.193 0.806
E20 Hypoparathyroidism
0.000 0.194 0.806
I77.8 Other specified disorders of arteries and arterioles
0.000 0.201 0.799
K90 Intestinal malabsorption
0.000 0.206 0.794
I74.8 Embolism and thrombosis of other arteries
0.000 0.209 0.791
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.216 0.784
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.231 0.769
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.239 0.761
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.244 0.756
E28 Ovarian dysfunction
0.000 0.244 0.756
D69.6 Thrombocytopenia, unspecified
0.000 0.246 0.754
E07.8 Other specified disorders of thyroid
0.000 0.246 0.754
E10.0 With coma
0.000 0.247 0.752
D69 Purpura and other haemorrhagic conditions
0.000 0.248 0.752
E10.2 With renal complications
0.000 0.249 0.750
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.252 0.748
I72.8 Aneurysm of other specified arteries
0.000 0.253 0.747
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.255 0.745
E06 Thyroiditis
0.000 0.257 0.743
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.257 0.742
L40.1 Generalised pustular psoriasis
0.737 0.263 0.000
E10.3 With ophthalmic complications
0.000 0.266 0.734
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.268 0.732
I77.2 Rupture of artery
0.000 0.269 0.731
K90.9 Intestinal malabsorption, unspecified
0.000 0.269 0.731
I72.3 Aneurysm of iliac artery
0.000 0.275 0.725
E50-E64 Other nutritional deficiencies
0.000 0.279 0.721
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M45.X6 Ankylosing spondylitis (Lumbar region)
0.716 0.283 0.000
E10.7 With multiple complications
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.287 0.713
E27.0 Other adrenocortical overactivity
0.000 0.287 0.713
L40.3 Pustulosis palmaris et plantaris
0.710 0.290 0.000
E10.6 With other specified complications
0.000 0.290 0.710
E12 Malnutrition-related diabetes mellitus
0.000 0.290 0.710
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.291 0.709
E32 Diseases of thymus
0.000 0.291 0.709
E31 Polyglandular dysfunction
0.000 0.291 0.709
E30 Disorders of puberty, not elsewhere classified
0.000 0.291 0.709
I77.5 Necrosis of artery
0.000 0.293 0.707
I77.4 Coeliac artery compression syndrome
0.000 0.293 0.707
I77.3 Arterial fibromuscular dysplasia
0.000 0.293 0.707
E03.8 Other specified hypothyroidism
0.000 0.295 0.705
E25 Adrenogenital disorders
0.000 0.305 0.695
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.306 0.694
D69.5 Secondary thrombocytopenia
0.000 0.317 0.683
E53 Deficiency of other B group vitamins
0.000 0.319 0.681
I71.0 Dissection of aorta [any part]
0.000 0.324 0.676
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.674 0.325 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.674 0.325 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.674 0.325 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.674 0.325 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.674 0.325 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.674 0.325 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.326 0.674
E06.3 Autoimmune thyroiditis
0.000 0.327 0.673
M45.X2 Ankylosing spondylitis (Cervical region)
0.671 0.329 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.329 0.671
L40-L45 Papulosquamous disorders
0.670 0.330 0.000
E28.3 Primary ovarian failure
0.000 0.332 0.668
E03.1 Congenital hypothyroidism without goitre
0.000 0.332 0.668
E40-E46 Malnutrition
0.000 0.347 0.653
E53.8 Deficiency of other specified B group vitamins
0.000 0.349 0.651
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.353 0.647
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.363 0.636
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.374 0.626
I72.4 Aneurysm of artery of lower extremity
0.000 0.379 0.621
I72.9 Aneurysm of unspecified site
0.000 0.384 0.616
I73.8 Other specified peripheral vascular diseases
0.000 0.385 0.615
E22 Hyperfunction of pituitary gland
0.000 0.390 0.610
E05.8 Other thyrotoxicosis
0.000 0.391 0.609
E10.5 With peripheral circulatory complications
0.000 0.392 0.608
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.393 0.607
E10.8 With unspecified complications
0.000 0.394 0.606
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.396 0.604
D69.4 Other primary thrombocytopenia
0.000 0.400 0.600
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.404 0.596
E34 Other endocrine disorders
0.000 0.406 0.594
I79.1 Aortitis in diseases classified elsewhere
0.000 0.408 0.592
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.408 0.592
I74.5 Embolism and thrombosis of iliac artery
0.000 0.411 0.589
I72.2 Aneurysm of renal artery
0.000 0.412 0.588
D69.2 Other nonthrombocytopenic purpura
0.000 0.416 0.584
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.418 0.581
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.418 0.581
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.420 0.580
E07.1 Dyshormogenetic goitre
0.000 0.422 0.578
E07.0 Hypersecretion of calcitonin
0.000 0.422 0.578
E20.8 Other hypoparathyroidism
0.000 0.422 0.578
E20.1 Pseudohypoparathyroidism
0.000 0.422 0.578
E20.0 Idiopathic hypoparathyroidism
0.000 0.422 0.578
E13 Other specified diabetes mellitus
0.000 0.429 0.571
K90.3 Pancreatic steatorrhoea
0.000 0.430 0.569
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.430 0.569
K90.1 Tropical sprue
0.000 0.430 0.569
I72.1 Aneurysm of artery of upper extremity
0.000 0.433 0.567
E27.9 Disorder of adrenal gland, unspecified
0.000 0.434 0.566
E27.8 Other specified disorders of adrenal gland
0.000 0.437 0.563
E16 Other disorders of pancreatic internal secretion
0.000 0.438 0.561
E29 Testicular dysfunction
0.000 0.440 0.560
D69.0 Allergic purpura
0.000 0.442 0.558
L43 Lichen planus
0.557 0.443 0.000
K90.8 Other intestinal malabsorption
0.000 0.444 0.556
I77.0 Arteriovenous fistula, acquired
0.000 0.447 0.553
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.448 0.552
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.454 0.546
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.457 0.543
E28.9 Ovarian dysfunction, unspecified
0.000 0.458 0.542
E28.8 Other ovarian dysfunction
0.000 0.458 0.542
E28.1 Androgen excess
0.000 0.458 0.542
E28.0 Oestrogen excess
0.000 0.458 0.542
D69.8 Other specified haemorrhagic conditions
0.000 0.460 0.539
L42 Pityriasis rosea
0.534 0.465 0.000
L41 Parapsoriasis
0.534 0.466 0.000
E06.4 Drug-induced thyroiditis
0.000 0.467 0.533
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.467 0.533
E06.0 Acute thyroiditis
0.000 0.467 0.533
E15 Nondiabetic hypoglycaemic coma
0.000 0.467 0.532
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.472 0.527
E10.4 With neurological complications
0.000 0.480 0.520
E23 Hypofunction and other disorders of pituitary gland
0.000 0.480 0.520
E51 Thiamine deficiency
0.000 0.482 0.518
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.483 0.517
E63 Other nutritional deficiencies
0.000 0.483 0.517
E50 Vitamin A deficiency
0.000 0.483 0.517
E60 Dietary zinc deficiency
0.000 0.483 0.517
E59 Dietary selenium deficiency
0.000 0.483 0.517
E52 Niacin deficiency [pellagra]
0.000 0.483 0.517
I70 Atherosclerosis
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.490 0.510
E12.9 Without complications
0.000 0.491 0.509
E12.8 With unspecified complications
0.000 0.491 0.509
E12.7 With multiple complications
0.000 0.491 0.509
E12.6 With other specified complications
0.000 0.491 0.509
E12.5 With peripheral circulatory complications
0.000 0.491 0.509
E12.4 With neurological complications
0.000 0.491 0.509
E12.3 With ophthalmic complications
0.000 0.491 0.509
E12.2 With renal complications
0.000 0.491 0.509
E12.1 With ketoacidosis
0.000 0.491 0.509
E12.0 With coma
0.000 0.491 0.509
E30.9 Disorder of puberty, unspecified
0.000 0.491 0.509
E30.8 Other disorders of puberty
0.000 0.491 0.509
E30.1 Precocious puberty
0.000 0.491 0.509
E30.0 Delayed puberty
0.000 0.491 0.509
E31.9 Polyglandular dysfunction, unspecified
0.000 0.491 0.509
E31.8 Other polyglandular dysfunction
0.000 0.491 0.509
E31.1 Polyglandular hyperfunction
0.000 0.491 0.509
E31.0 Autoimmune polyglandular failure
0.000 0.491 0.509
E32.9 Disease of thymus, unspecified
0.000 0.491 0.509
E32.8 Other diseases of thymus
0.000 0.491 0.509
E32.1 Abscess of thymus
0.000 0.491 0.509
E32.0 Persistent hyperplasia of thymus
0.000 0.491 0.509
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.491 0.509
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.491 0.509
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.491 0.509
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.492 0.508
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.494 0.506
D69.1 Qualitative platelet defects
0.000 0.497 0.502
E25.9 Adrenogenital disorder, unspecified
0.000 0.501 0.498
E25.8 Other adrenogenital disorders
0.000 0.501 0.498
E53.9 Vitamin B deficiency, unspecified
0.000 0.505 0.495
D69.9 Haemorrhagic condition, unspecified
0.000 0.506 0.494
E06.5 Other chronic thyroiditis
0.000 0.508 0.492
E56 Other vitamin deficiencies
0.000 0.509 0.490
E53.1 Pyridoxine deficiency
0.000 0.512 0.488
E53.0 Riboflavin deficiency
0.000 0.512 0.488
E34.8 Other specified endocrine disorders
0.000 0.512 0.488
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.516 0.484
E54 Ascorbic acid deficiency
0.000 0.517 0.482
L45 Papulosquamous disorders in diseases classified elsewhere
0.481 0.519 0.000
E14 Unspecified diabetes mellitus
0.000 0.520 0.480
I72.0 Aneurysm of carotid artery
0.000 0.520 0.480
E06.9 Thyroiditis, unspecified
0.000 0.526 0.474
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.532 0.468
E45 Retarded development following protein-energy malnutrition
0.000 0.532 0.468
E43 Unspecified severe protein-energy malnutrition
0.000 0.532 0.468
E42 Marasmic kwashiorkor
0.000 0.532 0.468
E41 Nutritional marasmus
0.000 0.532 0.468
E40 Kwashiorkor
0.000 0.532 0.468
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.533 0.467
E16.2 Hypoglycaemia, unspecified
0.000 0.534 0.466
J84 Other interstitial pulmonary diseases
0.000 0.541 0.459
E26 Hyperaldosteronism
0.001 0.542 0.458
E23.2 Diabetes insipidus
0.000 0.546 0.454
L44 Other papulosquamous disorders
0.452 0.548 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.549 0.451
L43.9 Lichen planus, unspecified
0.442 0.558 0.000
L43.8 Other lichen planus
0.440 0.560 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.562 0.437
E22.8 Other hyperfunction of pituitary gland
0.000 0.562 0.437
L41.1 Pityriasis lichenoides chronica
0.436 0.564 0.000
E58 Dietary calcium deficiency
0.000 0.567 0.432
E22.1 Hyperprolactinaemia
0.000 0.569 0.430
E34.5 Androgen resistance syndrome
0.000 0.574 0.426
E34.4 Constitutional tall stature
0.000 0.574 0.426
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.574 0.426
E34.1 Other hypersecretion of intestinal hormones
0.000 0.574 0.426
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.576 0.424
E34.9 Endocrine disorder, unspecified
0.000 0.583 0.417
E55 Vitamin D deficiency
0.000 0.588 0.411
E29.9 Testicular dysfunction, unspecified
0.000 0.589 0.411
E13.8 With unspecified complications
0.000 0.590 0.409
E13.7 With multiple complications
0.000 0.590 0.409
E13.6 With other specified complications
0.000 0.590 0.409
E13.5 With peripheral circulatory complications
0.000 0.590 0.409
E13.4 With neurological complications
0.000 0.590 0.409
E13.2 With renal complications
0.000 0.590 0.409
E13.1 With ketoacidosis
0.000 0.590 0.409
E13.0 With coma
0.000 0.590 0.409
E46 Unspecified protein-energy malnutrition
0.000 0.592 0.408
L43.0 Hypertrophic lichen planus
0.407 0.592 0.000
J84.8 Other specified interstitial pulmonary diseases
0.000 0.596 0.404
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.597 0.403
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.597 0.403
E16.4 Abnormal secretion of gastrin
0.000 0.597 0.403
E16.3 Increased secretion of glucagon
0.000 0.597 0.403
E29.8 Other testicular dysfunction
0.000 0.598 0.401
E29.0 Testicular hyperfunction
0.000 0.598 0.401
L43.3 Subacute (active) lichen planus
0.399 0.600 0.000
L43.2 Lichenoid drug reaction
0.399 0.600 0.000
L43.1 Bullous lichen planus
0.399 0.600 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.601 0.398
I70.9 Generalised and unspecified atherosclerosis
0.000 0.605 0.395
E16.1 Other hypoglycaemia
0.000 0.614 0.386
E06.1 Subacute thyroiditis
0.001 0.617 0.383
L41.9 Parapsoriasis, unspecified
0.383 0.617 0.000
L41.8 Other parapsoriasis
0.383 0.617 0.000
L41.5 Retiform parapsoriasis
0.383 0.617 0.000
L41.4 Large plaque parapsoriasis
0.383 0.617 0.000
L41.3 Small plaque parapsoriasis
0.383 0.617 0.000
L41.2 Lymphomatoid papulosis
0.383 0.617 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.383 0.617 0.000
E13.3 With ophthalmic complications
0.000 0.619 0.381
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.627 0.373
E23.1 Drug-induced hypopituitarism
0.000 0.627 0.373
E51.2 Wernicke's encephalopathy
0.000 0.627 0.373
E51.9 Thiamine deficiency, unspecified
0.000 0.628 0.372
E51.8 Other manifestations of thiamine deficiency
0.000 0.628 0.372
E51.1 Beriberi
0.000 0.628 0.372
E14.5 With peripheral circulatory complications
0.000 0.629 0.371
E50.9 Vitamin A deficiency, unspecified
0.000 0.629 0.371
E50.8 Other manifestations of vitamin A deficiency
0.000 0.629 0.371
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.629 0.371
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.629 0.371
E50.5 Vitamin A deficiency with night blindness
0.000 0.629 0.371
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.629 0.371
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.629 0.371
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.629 0.371
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.629 0.371
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.629 0.371
E63.9 Nutritional deficiency, unspecified
0.000 0.629 0.371
E63.8 Other specified nutritional deficiencies
0.000 0.629 0.371
E63.1 Imbalance of constituents of food intake
0.000 0.629 0.371
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.629 0.371
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.629 0.371
E64.8 Sequelae of other nutritional deficiencies
0.000 0.629 0.371
E64.3 Sequelae of rickets
0.000 0.629 0.371
E64.2 Sequelae of vitamin C deficiency
0.000 0.629 0.371
E64.1 Sequelae of vitamin A deficiency
0.000 0.629 0.371
E64.0 Sequelae of protein-energy malnutrition
0.000 0.629 0.371
E61 Deficiency of other nutrient elements
0.000 0.630 0.369
E14.2 Withrenal complications
0.000 0.631 0.369
E22.0 Acromegaly and pituitary gigantism
0.000 0.632 0.368
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.635 0.365
I78 Diseases of capillaries
0.000 0.637 0.363
I70.1 Atherosclerosis of renal artery
0.000 0.637 0.363
I70.8 Atherosclerosis of other arteries
0.000 0.638 0.362
E14.6 With other specified complications
0.000 0.646 0.353
E23.6 Other disorders of pituitary gland
0.000 0.648 0.352
E56.9 Vitamin deficiency, unspecified
0.000 0.648 0.352
E56.8 Deficiency of other vitamins
0.000 0.648 0.352
E56.0 Deficiency of vitamin E
0.000 0.648 0.352
E24 Cushing's syndrome
0.001 0.651 0.348
E28.2 Polycystic ovarian syndrome
0.000 0.651 0.348
E14.7 With multiple complications
0.000 0.656 0.344
E14.0 With coma
0.000 0.656 0.344
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.663 0.337
E44.1 Mild protein-energy malnutrition
0.000 0.664 0.336
E44.0 Moderate protein-energy malnutrition
0.000 0.664 0.336
E26.8 Other hyperaldosteronism
0.001 0.671 0.328
E26.1 Secondary hyperaldosteronism
0.001 0.671 0.328
E56.1 Deficiency of vitamin K
0.000 0.675 0.325
E14.1 With ketoacidosis
0.000 0.675 0.325
L44.9 Papulosquamous disorder, unspecified
0.324 0.676 0.000
L44.8 Other specified papulosquamous disorders
0.324 0.676 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.324 0.676 0.000
L44.3 Lichen ruber moniliformis
0.324 0.676 0.000
L44.2 Lichen striatus
0.324 0.676 0.000
L44.1 Lichen nitidus
0.324 0.676 0.000
E13.9 Without complications
0.000 0.684 0.315
E14.3 With ophthalmic complications
0.000 0.688 0.312
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.692 0.308
I70.0 Atherosclerosis of aorta
0.000 0.692 0.308
J84.0 Alveolar and parietoalveolar conditions
0.000 0.694 0.306
E04 Other non-toxic goitre
0.000 0.694 0.306
E14.4 With neurological complications
0.000 0.696 0.304
L44.0 Pityriasis rubra pilaris
0.295 0.704 0.000
E55.0 Rickets, active
0.000 0.705 0.295
E65-E68 Obesity and other hyperalimentation
0.000 0.710 0.290
E23.7 Disorder of pituitary gland, unspecified
0.000 0.711 0.288
E14.8 With unspecified complications
0.000 0.716 0.284
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.717 0.283
E26.9 Hyperaldosteronism, unspecified
0.001 0.719 0.280
J33.0 Polyp of nasal cavity
0.000 0.720 0.280
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.721 0.279
I78.9 Disease of capillaries, unspecified
0.000 0.724 0.275
E61.9 Deficiency of nutrient element, unspecified
0.000 0.735 0.265
E61.8 Deficiency of other specified nutrient elements
0.000 0.735 0.265
E61.7 Deficiency of multiple nutrient elements
0.000 0.735 0.265
E61.6 Vanadium deficiency
0.000 0.735 0.265
E61.5 Molybdenum deficiency
0.000 0.735 0.265
E61.4 Chromium deficiency
0.000 0.735 0.265
E61.3 Manganese deficiency
0.000 0.735 0.265
E61.0 Copper deficiency
0.000 0.735 0.265
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.740 0.260
E61.2 Magnesium deficiency
0.000 0.740 0.260
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.740 0.260
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.740 0.259
E14.9 Without complications
0.000 0.746 0.254
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.747 0.253
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.748 0.251
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.748 0.252
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.749 0.250
E24.3 Ectopic ACTH syndrome
0.001 0.749 0.250
E24.1 Nelson's syndrome
0.001 0.749 0.250
I78.8 Other diseases of capillaries
0.000 0.750 0.250
E04.0 Non-toxic diffuse goitre
0.000 0.751 0.249
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.751 0.249
D80-D89 Certain disorders involving the immune mechanism
0.000 0.754 0.246
E24.8 Other Cushing's syndrome
0.001 0.763 0.236
E24.2 Drug-induced Cushing's syndrome
0.001 0.764 0.235
D86.9 Sarcoidosis, unspecified
0.000 0.766 0.234
E29.1 Testicular hypofunction
0.000 0.769 0.231
D86 Sarcoidosis
0.000 0.770 0.230
E34.0 Carcinoid syndrome
0.001 0.770 0.229
D55-D59 Haemolytic anaemias
0.000 0.772 0.228
D68 Other coagulation defects
0.000 0.776 0.224
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.779 0.221
E04.8 Other specified non-toxic goitre
0.000 0.780 0.219
D59 Acquired haemolytic anaemia
0.000 0.783 0.217
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.786 0.214
D80 Immunodeficiency with predominantly antibody defects
0.000 0.789 0.211
D66 Hereditary factor VIII deficiency
0.000 0.791 0.209
E67 Other hyperalimentation
0.000 0.792 0.208
E68 Sequelae of hyperalimentation
0.000 0.792 0.208
D59.1 Other autoimmune haemolytic anaemias
0.000 0.794 0.206
E07.9 Disorder of thyroid, unspecified
0.000 0.796 0.203
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.796 0.203
D50-D53 Nutritional anaemias
0.000 0.799 0.201
J81 Pulmonary oedema
0.000 0.800 0.200
M35.3 Polymyalgia rheumatica
0.000 0.800 0.200
M35.0 Sicca syndrome [Sjogren]
0.000 0.802 0.198
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.802 0.198
E24.0 Pituitary-dependent Cushing's disease
0.001 0.803 0.196
M35 Other systemic involvement of connective tissue
0.000 0.806 0.194
D83 Common variable immunodeficiency
0.000 0.809 0.191
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.809 0.190
E55.9 Vitamin D deficiency, unspecified
0.000 0.810 0.189
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.813 0.187
D67 Hereditary factor IX deficiency
0.000 0.814 0.186
D84 Other immunodeficiencies
0.000 0.817 0.183
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.818 0.182
E26.0 Primary hyperaldosteronism
0.001 0.819 0.180
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.821 0.179
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.821 0.179
D50 Iron deficiency anaemia
0.000 0.822 0.178
D81 Combined immunodeficiencies
0.000 0.824 0.176
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.824 0.176
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.828 0.172
D82 Immunodeficiency associated with other major defects
0.000 0.832 0.168
E04.2 Non-toxic multinodular goitre
0.000 0.833 0.167
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.834 0.166
D68.5 Primary Thrombophilia
0.000 0.834 0.166
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.835 0.165
M35.1 Other overlap syndromes
0.000 0.835 0.165
D55 Anaemia due to enzyme disorders
0.000 0.836 0.164
J80 Adult respiratory distress syndrome
0.000 0.838 0.162
D58 Other hereditary haemolytic anaemias
0.000 0.839 0.161
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.841 0.159
D86.1 Sarcoidosis of lymph nodes
0.000 0.841 0.159
D52 Folate deficiency anaemia
0.000 0.843 0.157
D59.8 Other acquired haemolytic anaemias
0.000 0.844 0.156
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.844 0.156
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.844 0.156
D59.3 Haemolytic-uraemic syndrome
0.000 0.844 0.156
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.844 0.156
M35.7 Hypermobility syndrome
0.000 0.844 0.156
D57 Sickle-cell disorders
0.000 0.845 0.155
D68.9 Coagulation defect, unspecified
0.000 0.845 0.155
D50.9 Iron deficiency anaemia, unspecified
0.000 0.846 0.154
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.847 0.153
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.847 0.153
D68.1 Hereditary factor XI deficiency
0.000 0.847 0.153
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.847 0.153
D83.9 Common variable immunodeficiency, unspecified
0.000 0.848 0.152
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.849 0.151
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.849 0.151
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.849 0.151
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.849 0.151
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.849 0.151
M35.8 Other specified systemic involvement of connective tissue
0.000 0.850 0.150
E67.8 Other specified hyperalimentation
0.000 0.851 0.149
E67.3 Hypervitaminosis D
0.000 0.851 0.149
E67.2 Megavitamin-B6 syndrome
0.000 0.851 0.149
E67.1 Hypercarotenaemia
0.000 0.851 0.149
E67.0 Hypervitaminosis A
0.000 0.851 0.149
D68.4 Acquired coagulation factor deficiency
0.000 0.851 0.149
D86.3 Sarcoidosis of skin
0.000 0.851 0.149
D56 Thalassaemia
0.000 0.854 0.145
D53 Other nutritional anaemias
0.000 0.856 0.143
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.857 0.143
D68.6 Other Thrombophilia
0.000 0.860 0.140
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.860 0.140
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.860 0.140
M35.5 Multifocal fibrosclerosis
0.000 0.860 0.140
D68.2 Hereditary deficiency of other clotting factors
0.000 0.860 0.140
D58.0 Hereditary spherocytosis
0.000 0.862 0.138
D50.8 Other iron deficiency anaemias
0.000 0.863 0.137
D83.8 Other common variable immunodeficiencies
0.000 0.863 0.137
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.863 0.137
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.863 0.137
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.863 0.137
D68.0 Von Willebrand's disease
0.000 0.863 0.137
D84.1 Defects in the complement system
0.000 0.863 0.137
E65 Localised adiposity
0.000 0.863 0.136
J33 Nasal polyp
0.000 0.864 0.136
D84.9 Immunodeficiency, unspecified
0.000 0.864 0.136
D89.3 Immune reconstitution syndrome
0.000 0.866 0.134
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.866 0.134
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.866 0.134
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.866 0.134
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.866 0.134
E04.1 Non-toxic single thyroid nodule
0.000 0.867 0.133
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.868 0.132
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.869 0.131
E61.1 Iron deficiency
0.000 0.870 0.130
D84.8 Other specified immunodeficiencies
0.000 0.872 0.128
D50.1 Sideropenic dysphagia
0.000 0.872 0.128
D81.9 Combined immunodeficiency, unspecified
0.000 0.873 0.126
D81.8 Other combined immunodeficiencies
0.000 0.873 0.126
D81.7 Major histocompatibility complex class II deficiency
0.000 0.873 0.126
D81.6 Major histocompatibility complex class I deficiency
0.000 0.873 0.126
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.873 0.126
D81.4 Nezelof's syndrome
0.000 0.873 0.126
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.873 0.126

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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