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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596551
log Bayes Factor = 27.6033
Chromosome 6   position 31,332,239  (GRCh37) Explore rs2596551 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E65-E68 Obesity and other hyperalimentation
0.000 0.000 1.000
E66.8 Other obesity
0.000 0.000 1.000
E66 Obesity
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
E10 Insulin-dependent diabetes mellitus
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
L40-L45 Papulosquamous disorders
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.004 0.996
D86 Sarcoidosis
0.000 0.005 0.995
D80-D89 Certain disorders involving the immune mechanism
0.000 0.005 0.995
# Top node
0.000 0.005 0.995
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.005 0.995
J45.9 Asthma, unspecified
0.994 0.006 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.009 0.991
Chapter VI Diseases of the nervous system
0.000 0.012 0.988
M20-M25 Other joint disorders
0.000 0.013 0.987
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.014 0.986
D86.9 Sarcoidosis, unspecified
0.000 0.015 0.985
M07.3 Other psoriatic arthropathies
0.000 0.021 0.979
M07 Psoriatic and enteropathic arthropathies
0.000 0.022 0.978
M05-M14 Inflammatory polyarthropathies
0.000 0.022 0.978
M35 Other systemic involvement of connective tissue
0.000 0.026 0.974
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.029 0.971
D75 Other diseases of blood and blood-forming organs
0.000 0.032 0.968
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.034 0.966
M45 Ankylosing spondylitis
0.000 0.042 0.958
M45-M49 Spondylopathies
0.000 0.042 0.958
M25 Other joint disorders, not elsewhere classified
0.000 0.043 0.957
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.046 0.954
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.057 0.943
E06 Thyroiditis
0.000 0.057 0.943
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.060 0.940
D72 Other disorders of white blood cells
0.000 0.061 0.939
M35.0 Sicca syndrome [Sjogren]
0.000 0.063 0.937
D86.0 Sarcoidosis of lung
0.000 0.063 0.937
M25.5 Pain in joint
0.000 0.063 0.937
E10.2 With renal complications
0.000 0.068 0.932
D86.1 Sarcoidosis of lymph nodes
0.000 0.081 0.919
M60-M63 Disorders of muscles
0.000 0.088 0.912
E05.9 Thyrotoxicosis, unspecified
0.000 0.091 0.909
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.091 0.909
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.092 0.908
D72.8 Other specified disorders of white blood cells
0.000 0.097 0.903
G40-G47 Episodic and paroxysmal disorders
0.000 0.104 0.896
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.105 0.895
M25.56 Pain in joint (Lower leg)
0.000 0.112 0.888
M35.3 Polymyalgia rheumatica
0.000 0.113 0.887
G37 Other demyelinating diseases of central nervous system
0.000 0.117 0.883
N47 Redundant prepuce, phimosis and paraphimosis
0.880 0.120 0.000
G40 Epilepsy
0.000 0.124 0.876
E10.1 With ketoacidosis
0.000 0.126 0.874
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.134 0.866
E70-E90 Metabolic disorders
0.000 0.139 0.861
E66.0 Obesity due to excess calories
0.000 0.140 0.860
E10.5 With peripheral circulatory complications
0.000 0.140 0.860
L40.0 Psoriasis vulgaris
0.000 0.142 0.858
G47 Sleep disorders
0.000 0.149 0.851
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.149 0.851
E83 Disorders of mineral metabolism
0.000 0.150 0.850
E06.9 Thyroiditis, unspecified
0.000 0.151 0.849
M25.9 Joint disorder, unspecified
0.000 0.151 0.849
E50-E64 Other nutritional deficiencies
0.000 0.154 0.846
G47.9 Sleep disorder, unspecified
0.000 0.154 0.846
M62 Other disorders of muscle
0.000 0.155 0.845
Chapter V Mental and behavioural disorders
0.000 0.158 0.842
K90 Intestinal malabsorption
0.000 0.165 0.835
E06.3 Autoimmune thyroiditis
0.000 0.167 0.833
M33 Dermatopolymyositis
0.000 0.172 0.828
E10.4 With neurological complications
0.000 0.174 0.826
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.180 0.820
M62.8 Other specified disorders of muscle
0.000 0.182 0.818
E83.1 Disorders of iron metabolism
0.000 0.186 0.814
M34 Systemic sclerosis
0.000 0.187 0.813
D86.8 Sarcoidosis of other and combined sites
0.000 0.187 0.813
M35.7 Hypermobility syndrome
0.000 0.191 0.809
M24 Other specific joint derangements
0.000 0.192 0.808
M25.50 Pain in joint (Multiple sites)
0.000 0.193 0.807
M25.0 Haemarthrosis
0.000 0.193 0.807
L10-L14 Bullous disorders
0.000 0.193 0.807
E83.5 Disorders of calcium metabolism
0.000 0.194 0.806
M21 Other acquired deformities of limbs
0.000 0.196 0.804
M25.51 Pain in joint (Shoulder region)
0.000 0.203 0.797
L20-L30 Dermatitis and eczema
0.000 0.204 0.796
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.209 0.791
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.211 0.789
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.212 0.788
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.220 0.780
D86.3 Sarcoidosis of skin
0.000 0.226 0.774
M25.59 Pain in joint (Site unspecified)
0.000 0.228 0.772
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.229 0.771
D75.0 Familial erythrocytosis
0.000 0.231 0.769
D60-D64 Aplastic and other anaemias
0.000 0.233 0.767
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.235 0.765
G40.8 Other epilepsy
0.000 0.241 0.759
D75.1 Secondary polycythaemia
0.000 0.242 0.758
M25.96 Joint disorder, unspecified (Lower leg)
0.000 0.243 0.757
M25.4 Effusion of joint
0.000 0.244 0.756
F30-F39 Mood [affective] disorders
0.000 0.247 0.753
E65 Localised adiposity
0.000 0.249 0.751
M32 Systemic lupus erythematosus
0.000 0.249 0.751
E10.8 With unspecified complications
0.000 0.249 0.750
M25.58 Pain in joint (Other)
0.000 0.252 0.748
F80-F89 Disorders of psychological development
0.000 0.253 0.747
D61 Other aplastic anaemias
0.000 0.257 0.743
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.261 0.739
M00-M03 Infectious arthropathies
0.000 0.261 0.738
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.263 0.737
E89.0 Postprocedural hypothyroidism
0.000 0.263 0.737
M30 Polyarteritis nodosa and related conditions
0.000 0.267 0.733
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.269 0.731
D61.9 Aplastic anaemia, unspecified
0.000 0.274 0.726
M35.1 Other overlap syndromes
0.000 0.275 0.725
M25.97 Joint disorder, unspecified (Ankle and foot)
0.000 0.275 0.725
L40.8 Other psoriasis
0.000 0.279 0.721
M62.81 Other specified disorders of muscle (Shoulder region)
0.000 0.280 0.720
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.282 0.718
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E67 Other hyperalimentation
0.000 0.283 0.717
E68 Sequelae of hyperalimentation
0.000 0.283 0.717
E66.1 Drug-induced obesity
0.000 0.283 0.717
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.283 0.716
D55-D59 Haemolytic anaemias
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E10.7 With multiple complications
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
L44 Other papulosquamous disorders
0.000 0.286 0.714
L41 Parapsoriasis
0.000 0.286 0.714
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.286 0.714
G36 Other acute disseminated demyelination
0.000 0.286 0.714
D82 Immunodeficiency associated with other major defects
0.000 0.286 0.714
D81 Combined immunodeficiencies
0.000 0.286 0.714
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.286 0.714
E40-E46 Malnutrition
0.000 0.287 0.713
M33.1 Other dermatomyositis
0.000 0.289 0.711
M14 Arthropathies in other diseases classified elsewhere
0.000 0.291 0.709
D83 Common variable immunodeficiency
0.000 0.292 0.708
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.293 0.707
M21.4 Flat foot [pes planus] (acquired)
0.000 0.293 0.707
D74 Methaemoglobinaemia
0.000 0.293 0.707
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.293 0.707
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.293 0.707
D73 Diseases of spleen
0.000 0.293 0.707
F20 Schizophrenia
0.000 0.295 0.705
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.296 0.704
M07.38 Other psoriatic arthropathies (Other)
0.000 0.298 0.702
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.298 0.702
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.298 0.702
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.298 0.702
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.298 0.702
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.298 0.702
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.298 0.702
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.298 0.702
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.299 0.701
M07.6 Other enteropathic arthropathies
0.000 0.299 0.701
M07.5 Arthropathy in ulcerative colitis
0.000 0.299 0.701
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.299 0.701
M07.2 Psoriatic spondylitis
0.000 0.299 0.701
M07.1 Arthritis mutilans
0.000 0.299 0.701
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.299 0.701
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.299 0.701
M08 Juvenile arthritis
0.000 0.299 0.701
M25.06 Haemarthrosis (Lower leg)
0.000 0.301 0.699
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.302 0.698
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.302 0.698
M35.5 Multifocal fibrosclerosis
0.000 0.302 0.698
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.302 0.698
L28 Lichen simplex chronicus and prurigo
0.000 0.304 0.696
M60 Myositis
0.000 0.305 0.695
E55 Vitamin D deficiency
0.000 0.306 0.694
D72.1 Eosinophilia
0.000 0.310 0.690
M12 Other specific arthropathies
0.000 0.311 0.689
D75.2 Essential thrombocytosis
0.000 0.311 0.689
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.313 0.687
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.313 0.687
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.313 0.687
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.313 0.687
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.313 0.687
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.313 0.687
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.313 0.687
M25.2 Flail joint
0.000 0.314 0.686
M25.1 Fistula of joint
0.000 0.314 0.686
E53 Deficiency of other B group vitamins
0.000 0.314 0.686
E11 Non-insulin-dependent diabetes mellitus
0.000 0.315 0.685
G20-G26 Extrapyramidal and movement disorders
0.000 0.316 0.684
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.316 0.683
M24.2 Disorder of ligament
0.000 0.317 0.683
M91-M94 Chondropathies
0.000 0.319 0.681
M24.0 Loose body in joint
0.000 0.319 0.681
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.322 0.678
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.322 0.677
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.324 0.676
L58 Radiodermatitis
0.000 0.324 0.676
L55 Sunburn
0.000 0.324 0.676
E06.5 Other chronic thyroiditis
0.000 0.324 0.676
E06.4 Drug-induced thyroiditis
0.000 0.324 0.676
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.324 0.676
E06.1 Subacute thyroiditis
0.000 0.324 0.676
E06.0 Acute thyroiditis
0.000 0.324 0.676
M24.5 Contracture of joint
0.000 0.324 0.676
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.326 0.674
D72.9 Disorder of white blood cells, unspecified
0.000 0.327 0.673
D72.0 Genetic anomalies of leukocytes
0.000 0.327 0.673
F20.9 Schizophrenia, unspecified
0.000 0.328 0.672
F31 Bipolar affective disorder
0.000 0.328 0.672
M11 Other crystal arthropathies
0.000 0.328 0.672
M21.0 Valgus deformity, not elsewhere classified
0.000 0.328 0.672
L21 Seborrhoeic dermatitis
0.000 0.331 0.669
G47.2 Disorders of the sleep-wake schedule
0.000 0.333 0.667
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.334 0.666
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.336 0.663
E85 Amyloidosis
0.000 0.339 0.661
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.341 0.659
E83.4 Disorders of magnesium metabolism
0.000 0.341 0.659
L43 Lichen planus
0.000 0.341 0.659
M62.80 Other specified disorders of muscle (Multiple sites)
0.000 0.342 0.658
E10.6 With other specified complications
0.000 0.345 0.655
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.346 0.654
M61 Calcification and ossification of muscle
0.000 0.346 0.654
M34.8 Other forms of systemic sclerosis
0.000 0.346 0.654
L57.5 Actinic granuloma
0.000 0.348 0.651
L57.3 Poikiloderma of Civatte
0.000 0.348 0.651
L57.2 Cutis rhomboidalis nuchae
0.000 0.348 0.651
L57.1 Actinic reticuloid
0.000 0.348 0.651
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.349 0.651
L11 Other acantholytic disorders
0.000 0.353 0.647
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.354 0.646
M35.2 Behcet's disease
0.000 0.355 0.645
M49 Spondylopathies in diseases classified elsewhere
0.000 0.355 0.644
L27 Dermatitis due to substances taken internally
0.000 0.356 0.644
F39 Unspecified mood [affective] disorder
0.000 0.358 0.642
M34.1 CR(E)ST syndrome
0.000 0.358 0.642
F25 Schizoaffective disorders
0.000 0.361 0.639
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.362 0.638
L57.0 Actinic keratosis
0.000 0.365 0.635
G37.5 Concentric sclerosis [Balo]
0.000 0.367 0.633
G37.4 Subacute necrotising myelitis
0.000 0.367 0.633
G37.2 Central pontine myelinolysis
0.000 0.367 0.633
G37.1 Central demyelination of corpus callosum
0.000 0.367 0.633
G37.0 Diffuse sclerosis
0.000 0.367 0.633
K90-K93 Other diseases of the digestive system
0.000 0.368 0.632
F30 Manic episode
0.000 0.368 0.632
E10.0 With coma
0.000 0.369 0.631
M21.7 Unequal limb length (acquired)
0.000 0.369 0.631
G41 Status epilepticus
0.000 0.370 0.630
K90.8 Other intestinal malabsorption
0.000 0.370 0.629
M35.8 Other specified systemic involvement of connective tissue
0.000 0.371 0.629
E20-E35 Disorders of other endocrine glands
0.000 0.372 0.628
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.372 0.628
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.372 0.628
F22 Persistent delusional disorders
0.000 0.372 0.628
E05.8 Other thyrotoxicosis
0.000 0.372 0.627
G20 Parkinson's disease
0.000 0.374 0.626
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.375 0.625
M13 Other arthritis
0.000 0.376 0.624
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.376 0.623
L28.0 Lichen simplex chronicus
0.000 0.377 0.623
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.379 0.621
F84 Pervasive developmental disorders
0.000 0.380 0.620
E79 Disorders of purine and pyrimidine metabolism
0.000 0.383 0.617
E77 Disorders of glycoprotein metabolism
0.000 0.383 0.617
E76 Disorders of glycosaminoglycan metabolism
0.000 0.383 0.617
E72 Other disorders of amino-acid metabolism
0.000 0.383 0.617
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.383 0.617
E70 Disorders of aromatic amino-acid metabolism
0.000 0.383 0.617
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.383 0.617
M25.94 Joint disorder, unspecified (Hand)
0.000 0.383 0.617
M95.0 Acquired deformity of nose
0.000 0.384 0.616
E89.3 Postprocedural hypopituitarism
0.000 0.384 0.616
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.385 0.615
D84 Other immunodeficiencies
0.000 0.388 0.612
M25.42 Effusion of joint (Upper arm)
0.000 0.390 0.610
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.391 0.609
E83.8 Other disorders of mineral metabolism
0.000 0.391 0.609
E83.2 Disorders of zinc metabolism
0.000 0.391 0.609
E83.0 Disorders of copper metabolism
0.000 0.391 0.609
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.391 0.609
F60-F69 Disorders of adult personality and behaviour
0.000 0.391 0.609
M25.99 Joint disorder, unspecified (Site unspecified)
0.000 0.391 0.609
M25.98 Joint disorder, unspecified (Other)
0.000 0.391 0.609
M25.93 Joint disorder, unspecified (Forearm)
0.000 0.391 0.609
M25.92 Joint disorder, unspecified (Upper arm)
0.000 0.391 0.609
M25.90 Joint disorder, unspecified (Multiple sites)
0.000 0.391 0.609
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.393 0.607
E63 Other nutritional deficiencies
0.000 0.393 0.607
E56 Other vitamin deficiencies
0.000 0.393 0.607
E51 Thiamine deficiency
0.000 0.393 0.607
E50 Vitamin A deficiency
0.000 0.393 0.607
E60 Dietary zinc deficiency
0.000 0.393 0.607
E59 Dietary selenium deficiency
0.000 0.393 0.607
E54 Ascorbic acid deficiency
0.000 0.393 0.607
E52 Niacin deficiency [pellagra]
0.000 0.393 0.607
M62.9 Disorder of muscle, unspecified
0.000 0.394 0.606
M62.4 Contracture of muscle
0.000 0.394 0.606
M62.3 Immobility syndrome (paraplegic)
0.000 0.394 0.606
M62.2 Ischaemic infarction of muscle
0.000 0.394 0.606
M62.0 Diastasis of muscle
0.000 0.394 0.606
L12 Pemphigoid
0.000 0.394 0.606
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.394 0.606
E61 Deficiency of other nutrient elements
0.000 0.394 0.606
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.397 0.603
F70-F79 Mental retardation
0.000 0.397 0.603
E84 Cystic fibrosis
0.000 0.399 0.601
M25.91 Joint disorder, unspecified (Shoulder region)
0.000 0.399 0.600
K90.9 Intestinal malabsorption, unspecified
0.000 0.400 0.600
M33.2 Polymyositis
0.000 0.401 0.599
M24.27 Disorder of ligament (Ankle and foot)
0.000 0.401 0.599
K90.3 Pancreatic steatorrhoea
0.000 0.401 0.599
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.401 0.599
K90.1 Tropical sprue
0.000 0.401 0.599
D80 Immunodeficiency with predominantly antibody defects
0.000 0.402 0.597
F81 Specific developmental disorders of scholastic skills
0.000 0.403 0.597
E74 Other disorders of carbohydrate metabolism
0.000 0.403 0.597
D50-D53 Nutritional anaemias
0.000 0.405 0.595
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.406 0.594
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.000 0.406 0.594
M33.9 Dermatopolymyositis, unspecified
0.000 0.406 0.593
M33.0 Juvenile dermatomyositis
0.000 0.406 0.593
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.407 0.593
M25.40 Effusion of joint (Multiple sites)
0.000 0.407 0.593
M25.54 Pain in joint (Hand)
0.000 0.408 0.592
E58 Dietary calcium deficiency
0.000 0.409 0.591
L13 Other bullous disorders
0.000 0.411 0.589
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.412 0.588
M62.89 Other specified disorders of muscle (Site unspecified)
0.000 0.413 0.587
M62.87 Other specified disorders of muscle (Ankle and foot)
0.000 0.413 0.587
M62.84 Other specified disorders of muscle (Hand)
0.000 0.413 0.587
M62.83 Other specified disorders of muscle (Forearm)
0.000 0.413 0.587
M62.1 Other rupture of muscle (nontraumatic)
0.000 0.413 0.586
F80 Specific developmental disorders of speech and language
0.000 0.414 0.586
M25.43 Effusion of joint (Forearm)
0.000 0.415 0.585
E85.4 Organ-limited amyloidosis
0.000 0.415 0.585
E55.9 Vitamin D deficiency, unspecified
0.000 0.415 0.585
M24.8 Other specific joint derangements, not elsewhere classified
0.000 0.417 0.583
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.417 0.583
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.417 0.583
M34.0 Progressive systemic sclerosis
0.000 0.417 0.583
D61.1 Drug-induced aplastic anaemia
0.000 0.418 0.582
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.418 0.582
M14.6 Neuropathic arthropathy
0.000 0.420 0.580
M24.9 Joint derangement, unspecified
0.000 0.420 0.580
E11.5 With peripheral circulatory complications
0.000 0.421 0.579
M25.09 Haemarthrosis (Site unspecified)
0.000 0.421 0.579
M25.08 Haemarthrosis (Other)
0.000 0.421 0.579
M25.07 Haemarthrosis (Ankle and foot)
0.000 0.421 0.579
M25.05 Haemarthrosis (Pelvic region and thigh)
0.000 0.421 0.579
M25.04 Haemarthrosis (Hand)
0.000 0.421 0.579
M25.03 Haemarthrosis (Forearm)
0.000 0.421 0.579
M25.02 Haemarthrosis (Upper arm)
0.000 0.421 0.579
M25.01 Haemarthrosis (Shoulder region)
0.000 0.421 0.579
M25.00 Haemarthrosis (Multiple sites)
0.000 0.421 0.579
L10 Pemphigus
0.000 0.421 0.579
L14 Bullous disorders in diseases classified elsewhere
0.000 0.421 0.579
L25 Unspecified contact dermatitis
0.000 0.421 0.578
M25.3 Other instability of joint
0.000 0.422 0.578
E11.4 With neurological complications
0.000 0.422 0.578
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.422 0.578
M21.8 Other specified acquired deformities of limbs
0.000 0.424 0.576
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.424 0.576
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.425 0.575
L20 Atopic dermatitis
0.000 0.426 0.574
F99-F99 Unspecified mental disorder
0.000 0.427 0.573
E53.8 Deficiency of other specified B group vitamins
0.000 0.428 0.572
M34.9 Systemic sclerosis, unspecified
0.000 0.429 0.571
L24 Irritant contact dermatitis
0.000 0.429 0.571
L26 Exfoliative dermatitis
0.000 0.429 0.571
L22 Diaper [napkin] dermatitis
0.000 0.429 0.571
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.429 0.571
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.430 0.569
M25.44 Effusion of joint (Hand)
0.000 0.433 0.567
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.434 0.566
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.434 0.566
E89.5 Postprocedural testicular hypofunction
0.000 0.434 0.566
E89.1 Postprocedural hypoinsulinaemia
0.000 0.434 0.566
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.436 0.564
M24.7 Protrusio acetabuli
0.000 0.437 0.563
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.000 0.437 0.563
E11.6 With other specified complications
0.000 0.439 0.561
M24.6 Ankylosis of joint
0.000 0.440 0.560
F03 Unspecified dementia
0.000 0.441 0.559
M24.02 Loose body in joint (Upper arm)
0.000 0.441 0.559
D73.8 Other diseases of spleen
0.000 0.442 0.558
J45 Asthma
0.558 0.442 0.000
M00 Pyogenic arthritis
0.000 0.443 0.557
G47.4 Narcolepsy and cataplexy
0.000 0.443 0.556
E13 Other specified diabetes mellitus
0.000 0.444 0.556
E73 Lactose intolerance
0.000 0.445 0.555
D59 Acquired haemolytic anaemia
0.000 0.446 0.554
M21.9 Acquired deformity of limb, unspecified
0.000 0.446 0.554
G40.5 Special epileptic syndromes
0.000 0.447 0.553
F34 Persistent mood [affective] disorders
0.000 0.447 0.553
M62.6 Muscle strain
0.000 0.447 0.553
E89.2 Postprocedural hypoparathyroidism
0.000 0.447 0.552
D66 Hereditary factor VIII deficiency
0.000 0.447 0.552
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.448 0.551
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.451 0.549
F28 Other nonorganic psychotic disorders
0.000 0.452 0.548
F24 Induced delusional disorder
0.000 0.452 0.548
F21 Schizotypal disorder
0.000 0.452 0.548
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.452 0.548
M24.01 Loose body in joint (Shoulder region)
0.000 0.453 0.547
D68 Other coagulation defects
0.000 0.453 0.547
M62.86 Other specified disorders of muscle (Lower leg)
0.000 0.453 0.546
M24.4 Recurrent dislocation and subluxation of joint
0.000 0.454 0.546
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.456 0.544
M25.49 Effusion of joint (Site unspecified)
0.000 0.458 0.542
M25.48 Effusion of joint (Other)
0.000 0.458 0.542
M60.9 Myositis, unspecified
0.000 0.458 0.542
M24.54 Contracture of joint (Hand)
0.000 0.459 0.541
Chapter XXII Codes for special purposes
0.000 0.460 0.540
F38 Other mood [affective] disorders
0.000 0.460 0.540
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.461 0.538
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.461 0.538
M24.51 Contracture of joint (Shoulder region)
0.000 0.462 0.538
E89.4 Postprocedural ovarian failure
0.000 0.462 0.538
M25.52 Pain in joint (Upper arm)
0.000 0.462 0.538
E27 Other disorders of adrenal gland
0.000 0.463 0.537
F25.9 Schizoaffective disorder, unspecified
0.000 0.464 0.536
F89 Unspecified disorder of psychological development
0.000 0.464 0.535
F88 Other disorders of psychological development
0.000 0.464 0.535
F83 Mixed specific developmental disorders
0.000 0.464 0.535
F82 Specific developmental disorder of motor function
0.000 0.464 0.535
M05 Seropositive rheumatoid arthritis
0.000 0.465 0.535
D61.8 Other specified aplastic anaemias
0.000 0.467 0.533
D61.3 Idiopathic aplastic anaemia
0.000 0.467 0.533
D61.2 Aplastic anaemia due to other external agents
0.000 0.467 0.533
F30.9 Manic episode, unspecified
0.000 0.467 0.533
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.467 0.533
L11.0 Acquired keratosis follicularis
0.000 0.468 0.532
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.469 0.531
F22.0 Delusional disorder
0.000 0.470 0.530
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.470 0.530
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.470 0.529
M02 Reactive arthropathies
0.000 0.470 0.529
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.470 0.529
F84.5 Asperger's syndrome
0.000 0.470 0.529
M24.23 Disorder of ligament (Forearm)
0.000 0.472 0.528
L42 Pityriasis rosea
0.000 0.474 0.526
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.474 0.526
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.474 0.526
M30.2 Juvenile polyarteritis
0.000 0.474 0.526
M22 Disorders of patella
0.000 0.476 0.524
M21.3 Wrist or foot drop (acquired)
0.000 0.476 0.523
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.000 0.477 0.523
L43.8 Other lichen planus
0.000 0.478 0.522
D73.5 Infarction of spleen
0.000 0.479 0.521
D73.0 Hyposplenism
0.000 0.479 0.521
E11.3 With ophthalmic complications
0.000 0.480 0.520
L57.4 Cutis laxa senilis
0.000 0.481 0.519
M25.8 Other specified joint disorders
0.000 0.482 0.518
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.483 0.517
M25.7 Osteophyte
0.000 0.484 0.516
E16 Other disorders of pancreatic internal secretion
0.000 0.485 0.515
M24.56 Contracture of joint (Lower leg)
0.000 0.485 0.515
E15 Nondiabetic hypoglycaemic coma
0.000 0.485 0.514
E67.8 Other specified hyperalimentation
0.000 0.486 0.514
E67.3 Hypervitaminosis D
0.000 0.486 0.514
E67.2 Megavitamin-B6 syndrome
0.000 0.486 0.514
E67.1 Hypercarotenaemia
0.000 0.486 0.514
E67.0 Hypervitaminosis A
0.000 0.486 0.514
D55 Anaemia due to enzyme disorders
0.000 0.486 0.514
G30-G32 Other degenerative diseases of the nervous system
0.000 0.486 0.514
D56 Thalassaemia
0.000 0.487 0.513
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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