TreeWAS – Variant ID: rs261334

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H61.0 Perichondritis of external ear	0.085	0.915	0.000
H61 Other disorders of external ear	0.078	0.922	0.000
H61.2 Impacted cerumen	0.074	0.926	0.000
H61.3 Acquired stenosis of external ear canal	0.061	0.939	0.000
H61.9 Disorder of external ear, unspecified	0.058	0.942	0.000
H61.8 Other specified disorders of external ear	0.058	0.942	0.000
H61.1 Non-infective disorders of pinna	0.054	0.946	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.046	0.954	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.045	0.955	0.000
O12.0 Gestational oedema	0.045	0.955	0.000
H60-H62 Diseases of external ear	0.043	0.957	0.000
O16 Unspecified maternal hypertension	0.043	0.957	0.000
O12.1 Gestational proteinuria	0.043	0.957	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.042	0.958	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.037	0.963	0.000
O15 Eclampsia	0.035	0.965	0.000
O12.2 Gestational oedema with proteinuria	0.035	0.965	0.000
H60 Otitis externa	0.034	0.966	0.000
O14.0 Moderate preeclampsia	0.032	0.968	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.032	0.968	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.031	0.969	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.031	0.969	0.000
G47.9 Sleep disorder, unspecified	0.031	0.969	0.000
O14.1 Severe preeclampsia	0.029	0.971	0.000
H60.4 Cholesteatoma of external ear	0.029	0.971	0.000
O15.2 Eclampsia in the puerperium	0.027	0.972	0.000
O14.2 HELLP syndrome	0.027	0.973	0.000
H60.1 Cellulitis of external ear	0.026	0.974	0.000
H60.5 Acute otitis externa, non-infective	0.025	0.975	0.000
O15.9 Eclampsia, unspecified as to time period	0.025	0.975	0.000
O15.1 Eclampsia in labour	0.025	0.975	0.000
O15.0 Eclampsia in pregnancy	0.025	0.975	0.000
H60.0 Abscess of external ear	0.025	0.975	0.000
H60.2 Malignant otitis externa	0.024	0.976	0.000
H60.8 Other otitis externa	0.024	0.976	0.000
R09.0 Asphyxia	0.024	0.976	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.023	0.977	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.022	0.977	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.022	0.977	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.022	0.977	0.000
H62.2 Otitis externa in mycoses	0.022	0.977	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.022	0.977	0.000
H60.9 Otitis externa, unspecified	0.023	0.977	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.022	0.978	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.022	0.978	0.000
R09.1 Pleurisy	0.022	0.978	0.000
O14.9 Preeclampsia, unspecified	0.021	0.979	0.000
R09.2 Respiratory arrest	0.021	0.979	0.000
H60.3 Other infective otitis externa	0.020	0.979	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.016	0.984	0.000
R09.3 Abnormal sputum	0.015	0.985	0.000
J80 Adult respiratory distress syndrome	0.011	0.989	0.000
H66.3 Other chronic suppurative otitis media	0.011	0.989	0.000
J81 Pulmonary oedema	0.010	0.990	0.000
H40.0 Glaucoma suspect	0.010	0.990	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.010	0.990	0.000
Chapter VIII Diseases of the ear and mastoid process	0.009	0.991	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.991	0.009
H66 Suppurative and unspecified otitis media	0.009	0.991	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.009	0.991	0.000
H65-H75 Diseases of middle ear and mastoid	0.009	0.991	0.000
J69.0 Pneumonitis due to food and vomit	0.008	0.992	0.000
H70 Mastoiditis and related conditions	0.008	0.992	0.000
J84 Other interstitial pulmonary diseases	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.007	0.992	0.000
B37.3 Candidiasis of vulva and vagina	0.007	0.993	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.007	0.993	0.000
H70.9 Mastoiditis, unspecified	0.007	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.007	0.993	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.007	0.993	0.000
H65.3 Chronic mucoid otitis media	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.007	0.993	0.000
H68 Eustachian salpingitis and obstruction	0.007	0.993	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.993	0.007
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.994	0.000
H67 Otitis media in diseases classified elsewhere	0.006	0.994	0.000
G47 Sleep disorders	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.006	0.994	0.000
J84.8 Other specified interstitial pulmonary diseases	0.006	0.994	0.000
H70.0 Acute mastoiditis	0.006	0.994	0.000
J84.0 Alveolar and parietoalveolar conditions	0.006	0.994	0.000
H40.2 Primary angle-closure glaucoma	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
H70.8 Other mastoiditis and related conditions	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
H66.0 Acute suppurative otitis media	0.006	0.994	0.000
H70.2 Petrositis	0.006	0.994	0.000
G47.4 Narcolepsy and cataplexy	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
H40 Glaucoma	0.006	0.994	0.000
E10 Insulin-dependent diabetes mellitus	0.006	0.994	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.006	0.994	0.000
E10.4 With neurological complications	0.006	0.994	0.000
H70.1 Chronic mastoiditis	0.005	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
K07.3 Anomalies of tooth position	0.000	0.994	0.006
H65.4 Other chronic nonsuppurative otitis media	0.005	0.994	0.000
H20.9 Iridocyclitis, unspecified	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.005	0.994	0.000
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
F99 Mental disorder, not otherwise specified	0.005	0.995	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.995	0.005
H68.1 Obstruction of Eustachian tube	0.005	0.995	0.000
K07.4 Malocclusion, unspecified	0.000	0.995	0.005
E10.7 With multiple complications	0.005	0.995	0.000
E10.1 With ketoacidosis	0.005	0.995	0.000
H68.0 Eustachian salpingitis	0.005	0.995	0.000
K07 Dentofacial anomalies [including malocclusion]	0.000	0.995	0.005
S99.9 Unspecified injury of ankle and foot	0.005	0.995	0.000
E10.2 With renal complications	0.005	0.995	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.005	0.995	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.005	0.995	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.005	0.995	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
E10.0 With coma	0.005	0.995	0.000
G47.8 Other sleep disorders	0.005	0.995	0.000
H40.6 Glaucoma secondary to drugs	0.005	0.995	0.000
N90.7 Vulvar cyst	0.005	0.995	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.995	0.005
J69 Pneumonitis due to solids and liquids	0.005	0.995	0.000
H40.3 Glaucoma secondary to eye trauma	0.005	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
H40.8 Other glaucoma	0.005	0.995	0.000
G47.2 Disorders of the sleep-wake schedule	0.004	0.995	0.000
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.005	0.995	0.000
E10.9 Without complications	0.005	0.995	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.996	0.004
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.004	0.996	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.004	0.996	0.000
E10.8 With unspecified complications	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.004	0.996	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
J22 Unspecified acute lower respiratory infection	0.004	0.996	0.000
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
J20.9 Acute bronchitis, unspecified	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
H73.1 Chronic myringitis	0.004	0.996	0.000
K07.2 Anomalies of dental arch relationship	0.000	0.996	0.004
K07.6 Temporomandibular joint disorders	0.000	0.996	0.004
K75 Other inflammatory liver diseases	0.004	0.996	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.996	0.004
I26 Pulmonary embolism	0.004	0.996	0.000
S00.3 Superficial injury of nose	0.000	0.996	0.004
K07.9 Dentofacial anomaly, unspecified	0.000	0.996	0.004
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.996	0.004
J20 Acute bronchitis	0.004	0.996	0.000
K07.0 Major anomalies of jaw size	0.000	0.996	0.004
K22.5 Diverticulum of oesophagus, acquired	0.000	0.996	0.004
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
E10.6 With other specified complications	0.004	0.996	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.004	0.996	0.000
J69.8 Pneumonitis due to other solids and liquids	0.004	0.996	0.000
K07.5 Dentofacial functional abnormalities	0.000	0.996	0.004
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.004	0.996	0.000
H80-H83 Diseases of inner ear	0.004	0.996	0.000
J20-J22 Other acute lower respiratory infections	0.004	0.996	0.000
J69.1 Pneumonitis due to oils and essences	0.004	0.996	0.000
S90.8 Other superficial injuries of ankle and foot	0.004	0.996	0.000
K75.4 Autoimmune hepatitis	0.004	0.996	0.000
K07.8 Other dentofacial anomalies	0.000	0.996	0.003
K75.3 Granulomatous hepatitis, not elsewhere classified	0.004	0.996	0.000
S61.1 Open wound of finger(s) with damage to nail	0.004	0.996	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.996	0.004
S99.8 Other specified injuries of ankle and foot	0.003	0.996	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.996	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.996	0.000
H40.5 Glaucoma secondary to other eye disorders	0.003	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.997	0.000
J20.8 Acute bronchitis due to other specified organisms	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
H40.4 Glaucoma secondary to eye inflammation	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
S90.0 Contusion of ankle	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
J21 Acute bronchiolitis	0.003	0.997	0.000
K75.2 Nonspecific reactive hepatitis	0.003	0.997	0.000
K75.1 Phlebitis of portal vein	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
J20.7 Acute bronchitis due to echovirus	0.003	0.997	0.000
J20.6 Acute bronchitis due to rhinovirus	0.003	0.997	0.000
J20.5 Acute bronchitis due to respiratory syncytial virus	0.003	0.997	0.000
J20.4 Acute bronchitis due to parainfluenza virus	0.003	0.997	0.000
J20.3 Acute bronchitis due to coxsackie virus	0.003	0.997	0.000
J20.2 Acute bronchitis due to streptococcus	0.003	0.997	0.000
J20.1 Acute bronchitis due to Haemophilus influenzae	0.003	0.997	0.000
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
G40-G47 Episodic and paroxysmal disorders	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.997	0.003
N80.0 Endometriosis of uterus	0.000	0.997	0.003
G41 Status epilepticus	0.003	0.997	0.000
C51.9 Vulva, unspecified	0.003	0.997	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.997	0.003
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
S93.4 Sprain and strain of ankle	0.003	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.003	0.997	0.000
J21.9 Acute bronchiolitis, unspecified	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.003	0.997	0.000
K75.0 Abscess of liver	0.003	0.997	0.000
G43 Migraine	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.997	0.003
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
R40.0 Somnolence	0.003	0.997	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.003	0.997	0.000
G41.9 Status epilepticus, unspecified	0.003	0.997	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.997	0.003
U83 Resistance to other antibiotics	0.000	0.997	0.003
U82 Resistance to betalactam antibiotics	0.000	0.997	0.003
U85 Resistance to antineoplastic drugs	0.000	0.997	0.003
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
G40.5 Special epileptic syndromes	0.003	0.997	0.000
G46.3 Brain stem stroke syndrome	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.997	0.003
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.997	0.001
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.997	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.997	0.003
S92.7 Multiple fractures of foot	0.003	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.997	0.000
S94.1 Injury of medial plantar nerve	0.002	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.997	0.000
S95.1 Injury of plantar artery of foot	0.002	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.997	0.000
S97.0 Crushing injury of ankle	0.002	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
G41.0 Grand mal status epilepticus	0.003	0.997	0.000
G43.3 Complicated migraine	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.997	0.003
J21.8 Acute bronchiolitis due to other specified organisms	0.002	0.997	0.000
J21.1 Acute bronchiolitis due to human metapneumovirus	0.002	0.997	0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.002	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.002	0.997	0.000
G40 Epilepsy	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.002	0.997	0.000
G41.8 Other status epilepticus	0.002	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.997	0.000
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.997	0.000
S97.1 Crushing injury of toe(s)	0.002	0.997	0.000
G43.1 Migraine with aura [classical migraine]	0.003	0.997	0.000
G43.2 Status migrainosus	0.002	0.997	0.000
F99-F99 Unspecified mental disorder	0.003	0.997	0.000
H40-H42 Glaucoma	0.003	0.997	0.000
G41.2 Complex partial status epilepticus	0.002	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.997	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.002
G43.8 Other migraine	0.002	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.997	0.002
S91.0 Open wound of ankle	0.002	0.997	0.000
G41.1 Petit mal status epilepticus	0.002	0.997	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.002	0.998	0.000
G46.7 Other lacunar syndromes	0.002	0.998	0.000
G46.6 Pure sensory lacunar syndrome	0.002	0.998	0.000
G46.5 Pure motor lacunar syndrome	0.002	0.998	0.000
G46.2 Posterior cerebral artery syndrome	0.002	0.998	0.000
G46.1 Anterior cerebral artery syndrome	0.002	0.998	0.000
G46.0 Middle cerebral artery syndrome	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.998	0.002
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.998	0.002
U82.8 Resistance to other betalactam antibiotics	0.000	0.998	0.002
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.998	0.002
U82.1 Resistance to methicillin	0.000	0.998	0.002
U82.0 Resistance to penicillin	0.000	0.998	0.002
U83.9 Resistance to unspecified antibiotic	0.000	0.998	0.002
U83.8 Resistance to other single specified antibiotic	0.000	0.998	0.002
U83.7 Resistance to multiple antibiotics	0.000	0.998	0.002
U83.2 Resistance to quinolones	0.000	0.998	0.002
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.998	0.002
U83.0 Resistance to vancomycin	0.000	0.998	0.002
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.998	0.002
U84.8 Resistance to other specified antimicrobial drug	0.000	0.998	0.002
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.998	0.002
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.998	0.002
U84.2 Resistance to antiviral drug(s)	0.000	0.998	0.002
U84.1 Resistance to antifungal drug(s)	0.000	0.998	0.002
U84.0 Resistance to antiparasitic drug(s)	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
N92.3 Ovulation bleeding	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
K35 Acute appendicitis	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
G46.4 Cerebellar stroke syndrome	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
S00.7 Multiple superficial injuries of head	0.000	0.998	0.002
H42 Glaucoma in diseases classified elsewhere	0.002	0.998	0.000
G43.0 Migraine without aura [common migraine]	0.002	0.998	0.000
K81.1 Chronic cholecystitis	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
H81 Disorders of vestibular function	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
S00 Superficial injury of head	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.998	0.002
K35.9 Acute appendicitis, unspecified	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.000	0.998	0.002
Z12.5 Special screening examination for neoplasm of prostate	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
K12.0 Recurrent oral aphthae	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.998	0.002
J60-J70 Lung diseases due to external agents	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.998	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.998	0.002
J70 Respiratory conditions due to other external agents	0.002	0.998	0.000
I63.8 Other cerebral infarction	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
G47.3 Sleep apnoea	0.002	0.998	0.000
J70.4 Drug-induced interstitial lung disorder, unspecified	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
B37 Candidiasis	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.001	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.000
S00.4 Superficial injury of ear	0.000	0.998	0.002
C69.9 Eye, unspecified	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
R40.1 Stupor	0.002	0.998	0.000
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
C69.2 Retina	0.001	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
R40.2 Coma, unspecified	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.001	0.998	0.000
C69.5 Lachrymal gland and duct	0.001	0.998	0.000
C69.1 Cornea	0.001	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
J62 Pneumoconiosis due to dust containing silica	0.001	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.001	0.998	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.001	0.998	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.001	0.998	0.000
J66 Airway disease due to specific organic dust	0.001	0.998	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.001	0.998	0.000
J65 Pneumoconiosis associated with tuberculosis	0.001	0.998	0.000
C51.0 Labium majus	0.001	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.001	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.001	0.998	0.000
F52.7 Excessive sexual drive	0.001	0.998	0.000
F52.6 Nonorganic dyspareunia	0.001	0.998	0.000
F52.5 Nonorganic vaginismus	0.001	0.998	0.000
F52.4 Premature ejaculation	0.001	0.998	0.000
F52.3 Orgasmic dysfunction	0.001	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.001	0.998	0.000
G44.0 Cluster headache syndrome	0.001	0.998	0.000
H74.1 Adhesive middle ear disease	0.001	0.998	0.000
J60 Coalworker's pneumoconiosis	0.001	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
J70.9 Respiratory conditions due to unspecified external agent	0.001	0.998	0.000
J70.8 Respiratory conditions due to other specified external agents	0.001	0.998	0.000
J70.3 Chronic drug-induced interstitial lung disorders	0.001	0.998	0.000
J70.2 Acute drug-induced interstitial lung disorders	0.001	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.998	0.001
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.998	0.000
B37.7 Candidal septicaemia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations