TreeWAS – Variant ID: rs261532

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.0 Disorders of both mitral and aortic valves	0.000	0.954	0.046
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.954	0.046
I08 Multiple valve diseases	0.000	0.955	0.045
I08.8 Other multiple valve diseases	0.000	0.958	0.042
I08.9 Multiple valve disease, unspecified	0.000	0.968	0.031
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.973	0.027
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.973	0.027
I84.2 Internal haemorrhoids without complication	0.000	0.978	0.022
F31.9 Bipolar affective disorder, unspecified	0.022	0.978	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.979	0.021
J81 Pulmonary oedema	0.000	0.982	0.018
F31 Bipolar affective disorder	0.017	0.983	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.015	0.985	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.015	0.985	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.985	0.015
F31.7 Bipolar affective disorder, currently in remission	0.014	0.986	0.000
F31.8 Other bipolar affective disorders	0.014	0.986	0.000
E10.3 With ophthalmic complications	0.014	0.986	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.987	0.013
E10 Insulin-dependent diabetes mellitus	0.013	0.987	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.012	0.988	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.012	0.988	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.012	0.988	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.012	0.988	0.000
R16.1 Splenomegaly, not elsewhere classified	0.012	0.988	0.000
E10.1 With ketoacidosis	0.012	0.988	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.011	0.989	0.000
E10.8 With unspecified complications	0.011	0.989	0.000
E10.9 Without complications	0.011	0.989	0.000
O03.4 Incomplete, without complication	0.011	0.989	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.990	0.010
J84 Other interstitial pulmonary diseases	0.000	0.990	0.010
E10.6 With other specified complications	0.010	0.990	0.000
E10.0 With coma	0.010	0.990	0.000
E10.5 With peripheral circulatory complications	0.009	0.991	0.000
F00 Dementia in Alzheimer's disease	0.000	0.991	0.009
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.991	0.009
E10.2 With renal complications	0.009	0.991	0.000
E10.7 With multiple complications	0.009	0.991	0.000
G30 Alzheimer's disease	0.000	0.991	0.009
J84.8 Other specified interstitial pulmonary diseases	0.000	0.991	0.008
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.992	0.008
E10.4 With neurological complications	0.008	0.992	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.992	0.008
G30.0 Alzheimer's disease with early onset	0.000	0.992	0.008
T23.2 Burn of second degree of wrist and hand	0.000	0.992	0.008
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.992	0.008
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.992	0.008
I05-I09 Chronic rheumatic heart diseases	0.000	0.992	0.008
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.993	0.007
G30.8 Other Alzheimer's disease	0.000	0.993	0.007
T20 Burn and corrosion of head and neck	0.000	0.993	0.007
J84.0 Alveolar and parietoalveolar conditions	0.000	0.993	0.007
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.993	0.007
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.993	0.007
G30.1 Alzheimer's disease with late onset	0.000	0.993	0.007
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.993	0.007
R44.3 Hallucinations, unspecified	0.007	0.993	0.000
J80 Adult respiratory distress syndrome	0.000	0.993	0.007
T20.0 Burn of unspecified degree of head and neck	0.000	0.993	0.006
R44 Other symptoms and signs involving general sensations and perceptions	0.006	0.994	0.000
T21 Burn and corrosion of trunk	0.000	0.994	0.006
R44.1 Visual hallucinations	0.006	0.994	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.994	0.006
R44.0 Auditory hallucinations	0.006	0.994	0.000
T20.1 Burn of first degree of head and neck	0.000	0.994	0.006
T23.3 Burn of third degree of wrist and hand	0.000	0.994	0.006
K37 Unspecified appendicitis	0.000	0.994	0.006
T25 Burn and corrosion of ankle and foot	0.000	0.994	0.006
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.994	0.006
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.994	0.006
T23.7 Corrosion of third degree of wrist and hand	0.000	0.994	0.006
T23.6 Corrosion of second degree of wrist and hand	0.000	0.994	0.006
T23.5 Corrosion of first degree of wrist and hand	0.000	0.994	0.006
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.994	0.006
R74.8 Abnormal levels of other serum enzymes	0.000	0.994	0.006
O03 Spontaneous abortion	0.006	0.994	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.994	0.006
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.994	0.005
R74 Abnormal serum enzyme levels	0.000	0.994	0.006
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.994	0.005
I06 Rheumatic aortic valve diseases	0.000	0.995	0.005
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.005	0.995	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.995	0.005
T20.2 Burn of second degree of head and neck	0.000	0.995	0.005
T20.7 Corrosion of third degree of head and neck	0.000	0.995	0.005
T20.6 Corrosion of second degree of head and neck	0.000	0.995	0.005
T20.5 Corrosion of first degree of head and neck	0.000	0.995	0.005
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.995	0.005
T20.3 Burn of third degree of head and neck	0.000	0.995	0.005
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
I09 Other rheumatic heart diseases	0.000	0.995	0.005
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T21.2 Burn of second degree of trunk	0.000	0.995	0.005
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.995	0.005
T21.3 Burn of third degree of trunk	0.000	0.995	0.005
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T25.3 Burn of third degree of ankle and foot	0.000	0.995	0.005
T25.2 Burn of second degree of ankle and foot	0.000	0.995	0.005
O03.3 Incomplete, with other and unspecified complications	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T45.5 Anticoagulants	0.005	0.995	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
F03 Unspecified dementia	0.000	0.995	0.005
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.995	0.005
R44.2 Other hallucinations	0.005	0.995	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.995	0.005
T21.7 Corrosion of third degree of trunk	0.000	0.995	0.005
T21.6 Corrosion of second degree of trunk	0.000	0.995	0.005
T21.5 Corrosion of first degree of trunk	0.000	0.995	0.005
T21.4 Corrosion of unspecified degree of trunk	0.000	0.995	0.005
T21.1 Burn of first degree of trunk	0.000	0.995	0.005
W10.8 Other specified place	0.005	0.995	0.000
T21.0 Burn of unspecified degree of trunk	0.000	0.995	0.005
R77 Other abnormalities of plasma proteins	0.000	0.995	0.005
O03.8 Complete or unspecified, with other and unspecified complications	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
T25.7 Corrosion of third degree of ankle and foot	0.000	0.995	0.004
T25.6 Corrosion of second degree of ankle and foot	0.000	0.995	0.004
T25.5 Corrosion of first degree of ankle and foot	0.000	0.995	0.004
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.995	0.004
T25.1 Burn of first degree of ankle and foot	0.000	0.995	0.004
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
R77.9 Abnormality of plasma protein, unspecified	0.000	0.995	0.005
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.995	0.004
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.995	0.005
O03.7 Complete or unspecified, complicated by embolism	0.004	0.995	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.995	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.995	0.000
O03.2 Incomplete, complicated by embolism	0.004	0.995	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.995	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
S42.20 Fracture of upper end of humerus (closed)	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
I30.9 Acute pericarditis, unspecified	0.004	0.996	0.000
H55 Nystagmus and other irregular eye movements	0.004	0.996	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.996	0.004
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
R40.2 Coma, unspecified	0.004	0.996	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.996	0.004
I06.8 Other rheumatic aortic valve diseases	0.000	0.996	0.004
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.996	0.004
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
R40 Somnolence, stupor and coma	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
O03.9 Complete or unspecified, without complication	0.004	0.996	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.996	0.004
I06.1 Rheumatic aortic insufficiency	0.000	0.996	0.004
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
I09.8 Other specified rheumatic heart diseases	0.000	0.996	0.004
I09.2 Chronic rheumatic pericarditis	0.000	0.996	0.004
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.996	0.004
I09.0 Rheumatic myocarditis	0.000	0.996	0.004
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.004	0.996	0.000
R77.8 Other specified abnormalities of plasma proteins	0.000	0.996	0.004
W19.3 Sports and athletics area	0.000	0.996	0.004
R76 Other abnormal immunological findings in serum	0.000	0.996	0.004
I06.0 Rheumatic aortic stenosis	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
R40.0 Somnolence	0.004	0.996	0.000
F01 Vascular dementia	0.000	0.996	0.004
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.000	0.996	0.004
W19.4 Street and highway	0.000	0.996	0.004
R77.2 Abnormality of alphafetoprotein	0.000	0.996	0.004
R77.0 Abnormality of albumin	0.000	0.996	0.004
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.996	0.004
R77.1 Abnormality of globulin	0.000	0.996	0.004
R40.1 Stupor	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.996	0.000
T42.3 Barbiturates	0.003	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.996	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
D23.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
H47.1 Papilloedema, unspecified	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
R71 Abnormality of red blood cells	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.996	0.003
I07.8 Other tricuspid valve diseases	0.000	0.996	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.996	0.003
I07.0 Tricuspid stenosis	0.000	0.996	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.004	0.996	0.000
F09 Unspecified organic or symptomatic mental disorder	0.000	0.996	0.003
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.996	0.003
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.997	0.003
R79 Other abnormal findings of blood chemistry	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
R73 Elevated blood glucose level	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
K76.8 Other specified diseases of liver	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.003
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.997	0.003
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.997	0.003
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
R76.2 False-positive serological test for syphilis	0.000	0.997	0.003
R76.1 Abnormal reaction to tuberculin test	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.003	0.997	0.000
F34.1 Dysthymia	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.000	0.997	0.003
F02 Dementia in other diseases classified elsewhere	0.000	0.997	0.003
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.997	0.003
F01.8 Other vascular dementia	0.000	0.997	0.003
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.997	0.003
F01.2 Subcortical vascular dementia	0.000	0.997	0.003
F01.0 Vascular dementia of acute onset	0.000	0.997	0.003
R73.0 Abnormal glucose tolerance test	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.003
R78.0 Finding of alcohol in blood	0.000	0.997	0.003
F34 Persistent mood [affective] disorders	0.003	0.997	0.000
F01.1 Multi-infarct dementia	0.000	0.997	0.003
G44.2 Tension-type headache	0.000	0.997	0.003
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.000	0.997	0.003
R78.7 Finding of abnormal level of heavy metals in blood	0.000	0.997	0.003
R78.6 Finding of steroid agent in blood	0.000	0.997	0.003
R78.5 Finding of psychotropic drug in blood	0.000	0.997	0.003
R78.4 Finding of other drugs of addictive potential in blood	0.000	0.997	0.003
R78.3 Finding of hallucinogen in blood	0.000	0.997	0.003
R78.2 Finding of cocaine in blood	0.000	0.997	0.003
R78.1 Finding of opiate drug in blood	0.000	0.997	0.003
F05.8 Other delirium	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
F07.2 Postconcussional syndrome	0.000	0.997	0.003
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.997	0.002
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.997	0.002
F07.1 Postencephalitic syndrome	0.000	0.997	0.002
T41.5 Therapeutic gases	0.002	0.997	0.000
T41.4 Anaesthetic, unspecified	0.002	0.997	0.000
T41.3 Local anaesthetics	0.002	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
T41.1 Intravenous anaesthetics	0.002	0.997	0.000
T41.0 Inhaled anaesthetics	0.002	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.002	0.997	0.000
T49.8 Other topical agents	0.002	0.997	0.000
T49.7 Dental drugs, topically applied	0.002	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.997	0.000
T49.2 Local astringents and local detergents	0.002	0.997	0.000
T49.1 Antipruritics	0.002	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.003	0.997	0.000
R45.2 Unhappiness	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
T37.5 Antiviral drugs	0.002	0.997	0.000
T37.4 Anthelminthics	0.002	0.997	0.000
T37.3 Other antiprotozoal drugs	0.002	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
T37.1 Antimycobacterial drugs	0.002	0.997	0.000
T37.0 Sulphonamides	0.002	0.997	0.000
Z83.3 Family history of diabetes mellitus	0.003	0.997	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.997	0.003
R78.8 Finding of other specified substances, not normally found in blood	0.000	0.997	0.002
F02.3 Dementia in Parkinson's disease	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.002	0.997	0.000
R45 Symptoms and signs involving emotional state	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.997	0.000
R41.1 Anterograde amnesia	0.003	0.997	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.997	0.000
T36.8 Other systemic antibiotics	0.002	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
T36.6 Rifamycins	0.002	0.997	0.000
T36.5 Aminoglycosides	0.002	0.997	0.000
T36.4 Tetracyclines	0.002	0.997	0.000
T36.3 Macrolides	0.002	0.997	0.000
T36.2 Chloramphenicol group	0.002	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.997	0.002
R76.0 Raised antibody titer	0.000	0.997	0.002
B02.9 Zoster without complication	0.003	0.997	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
R43 Disturbances of smell and taste	0.002	0.997	0.000
F07.0 Organic personality disorder	0.000	0.997	0.002
R70.1 Abnormal plasma viscosity	0.000	0.997	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
D64.9 Anaemia, unspecified	0.000	0.997	0.003
W10 Fall on and from stairs and steps	0.002	0.997	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.002
F02.2 Dementia in Huntington's disease	0.000	0.998	0.002
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.002
Z96.7 Presence of other bone and tendon implants	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
R41.3 Other amnesia	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.000	0.998	0.002
R79.0 Abnormal level of blood mineral	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
W10.3 Sports and athletics area	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
T50.8 Diagnostic agents	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
R45.7 State of emotional shock and stress, unspecified	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.998	0.002
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
D64.8 Other specified anaemias	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
W19 Unspecified fall	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
R43.1 Parosmia	0.002	0.998	0.000
R09.1 Pleurisy	0.000	0.998	0.002
C17.9 Small intestine, unspecified	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
O61.0 Failed medical induction of labour	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
R43.0 Anosmia	0.002	0.998	0.000
R45.6 Physical violence	0.002	0.998	0.000
R45.5 Hostility	0.002	0.998	0.000
R45.3 Demoralisation and apathy	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.998	0.001
F06.5 Organic dissociative disorder	0.001	0.998	0.001
F06.4 Organic anxiety disorder	0.001	0.998	0.001
F06.3 Organic mood [affective] disorders	0.001	0.998	0.001
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.998	0.001
F06.1 Organic catatonic disorder	0.001	0.998	0.001
F06.0 Organic hallucinosis	0.001	0.998	0.001
W10.6 Industrial and construction area	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.002	0.998	0.000
W19.6 Industrial and construction area	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.998	0.000
R43.2 Parageusia	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.998	0.001
W10.9 Unspecified place	0.002	0.998	0.000
W10.5 Trade and service area	0.002	0.998	0.000
W10.2 School, other institution and public administrative area	0.002	0.998	0.000
W10.0 Home	0.002	0.998	0.000
W10.7 Farm	0.002	0.998	0.000
W10.1 Residential institution	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
W19.1 Residential institution	0.000	0.998	0.002
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.998	0.001
R45.0 Nervousness	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
T39.0 Salicylates	0.002	0.998	0.000
Y45.1 Salicylates	0.000	0.998	0.002
D64 Other anaemias	0.000	0.998	0.002
C22.9 Liver, unspecified	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
R46 Symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
R45.4 Irritability and anger	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
C22.0 Liver cell carcinoma	0.002	0.998	0.000
W19.8 Other specified place	0.000	0.998	0.002
W19.5 Trade and service area	0.000	0.998	0.002
W19.0 Home	0.000	0.998	0.002
W19.7 Farm	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.002	0.998	0.000
Z83 Family history of other specific disorders	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.001
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
Z29.0 Isolation	0.002	0.998	0.000
Z83.6 Family history of diseases of the respiratory system	0.002	0.998	0.000
I87 Other disorders of veins	0.002	0.998	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
B02 Zoster [herpes zoster]	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.998	0.002
W10.08 Fall on and from stairs and steps; Home; While engaged in other specified activities	0.001	0.998	0.000
W10.04 Fall on and from stairs and steps; Home; While resting, sleeping, eating or engaging in other vital activities	0.001	0.998	0.000
W10.03 Fall on and from stairs and steps; Home; While engaged in other types of work	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations