TreeWAS – Variant ID: rs2621366

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.000	0.003	0.997
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.003	0.997
E05.9 Thyrotoxicosis, unspecified	0.000	0.003	0.997
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.005	0.995
E10.4 With neurological complications	0.000	0.018	0.982
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.032	0.968
E16 Other disorders of pancreatic internal secretion	0.000	0.053	0.947
E10.2 With renal complications	0.000	0.060	0.940
E16.2 Hypoglycaemia, unspecified	0.000	0.072	0.928
E10.8 With unspecified complications	0.000	0.096	0.904
E07 Other disorders of thyroid	0.000	0.109	0.891
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.115	0.885
E14 Unspecified diabetes mellitus	0.000	0.126	0.874
E10.0 With coma	0.000	0.133	0.867
E10.6 With other specified complications	0.000	0.150	0.850
I25.8 Other forms of chronic ischaemic heart disease	0.838	0.162	0.000
I25 Chronic ischaemic heart disease	0.833	0.167	0.000
L40.0 Psoriasis vulgaris	0.831	0.169	0.000
E14.3 With ophthalmic complications	0.000	0.178	0.822
L40.1 Generalised pustular psoriasis	0.822	0.178	0.000
E40-E46 Malnutrition	0.000	0.178	0.822
E10.5 With peripheral circulatory complications	0.000	0.185	0.815
I20-I25 Ischaemic heart diseases	0.813	0.187	0.000
L40.4 Guttate psoriasis	0.804	0.196	0.000
C44.2 Skin of ear and external auricular canal	0.804	0.196	0.000
I21 Acute myocardial infarction	0.803	0.197	0.000
C44 Other malignant neoplasms of skin	0.796	0.204	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.792	0.208	0.000
C44.7 Skin of lower limb, including hip	0.779	0.221	0.000
L40.8 Other psoriasis	0.765	0.235	0.000
C44.4 Skin of scalp and neck	0.759	0.241	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.759	0.241	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.241	0.759
I25.9 Chronic ischaemic heart disease, unspecified	0.757	0.243	0.000
I25.2 Old myocardial infarction	0.754	0.246	0.000
C44.3 Skin of other and unspecified parts of face	0.747	0.253	0.000
E07.8 Other specified disorders of thyroid	0.000	0.258	0.742
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.269	0.731
I24 Other acute ischaemic heart diseases	0.724	0.276	0.000
I21.9 Acute myocardial infarction, unspecified	0.720	0.280	0.000
E10.7 With multiple complications	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.716	0.284	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.285	0.715
E03.1 Congenital hypothyroidism without goitre	0.000	0.297	0.703
E46 Unspecified protein-energy malnutrition	0.000	0.303	0.697
E16.1 Other hypoglycaemia	0.000	0.305	0.695
E15 Nondiabetic hypoglycaemic coma	0.000	0.306	0.694
E14.8 With unspecified complications	0.000	0.313	0.687
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.321	0.679
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.321	0.679
E16.4 Abnormal secretion of gastrin	0.000	0.321	0.679
E16.3 Increased secretion of glucagon	0.000	0.321	0.679
I23 Certain current complications following acute myocardial infarction	0.677	0.323	0.000
E03.8 Other specified hypothyroidism	0.000	0.333	0.667
E14.6 With other specified complications	0.000	0.341	0.659
L40.3 Pustulosis palmaris et plantaris	0.658	0.342	0.000
I24.8 Other forms of acute ischaemic heart disease	0.656	0.344	0.000
K90 Intestinal malabsorption	0.000	0.360	0.639
E07.1 Dyshormogenetic goitre	0.000	0.361	0.639
E07.0 Hypersecretion of calcitonin	0.000	0.361	0.639
I22 Subsequent myocardial infarction	0.639	0.361	0.000
E14.5 With peripheral circulatory complications	0.000	0.363	0.637
E14.7 With multiple complications	0.000	0.374	0.626
E14.2 Withrenal complications	0.000	0.374	0.626
E14.0 With coma	0.000	0.374	0.626
I24.9 Acute ischaemic heart disease, unspecified	0.622	0.378	0.000
E05.8 Other thyrotoxicosis	0.000	0.380	0.620
E14.1 With ketoacidosis	0.000	0.386	0.614
I22.1 Subsequent myocardial infarction of inferior wall	0.604	0.396	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.400	0.600
C44.9 Malignant neoplasm of skin, unspecified	0.598	0.402	0.000
I25.6 Silent myocardial ischaemia	0.597	0.403	0.000
C44.5 Skin of trunk	0.595	0.405	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.406	0.594
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.410	0.589
E45 Retarded development following protein-energy malnutrition	0.000	0.410	0.589
E43 Unspecified severe protein-energy malnutrition	0.000	0.410	0.589
E42 Marasmic kwashiorkor	0.000	0.410	0.589
E41 Nutritional marasmus	0.000	0.410	0.589
E40 Kwashiorkor	0.000	0.410	0.589
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.588	0.412	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.576	0.424	0.000
C44.8 Overlapping lesion of skin	0.571	0.429	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.442	0.558
L40-L45 Papulosquamous disorders	0.552	0.448	0.000
J45 Asthma	0.000	0.458	0.542
E14.4 With neurological complications	0.000	0.463	0.536
I25.1 Atherosclerotic heart disease	0.534	0.466	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.524	0.476	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
E65-E68 Obesity and other hyperalimentation	0.000	0.494	0.506
I25.4 Coronary artery aneurysm	0.504	0.496	0.000
E13 Other specified diabetes mellitus	0.000	0.501	0.498
C44.0 Skin of lip	0.498	0.502	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.493	0.506	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.486	0.514	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.486	0.514	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.486	0.514	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.486	0.514	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.486	0.514	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.486	0.514	0.000
K90.8 Other intestinal malabsorption	0.000	0.514	0.486
C44.1 Skin of eyelid, including canthus	0.477	0.523	0.000
I22.8 Subsequent myocardial infarction of other sites	0.476	0.524	0.000
I24.1 Dressler's syndrome	0.471	0.528	0.000
I23.8 Other current complications following acute myocardial infarction	0.470	0.530	0.000
E50-E64 Other nutritional deficiencies	0.000	0.537	0.463
I25.5 Ischaemic cardiomyopathy	0.462	0.537	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.541	0.459
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.541	0.459
K90.1 Tropical sprue	0.000	0.541	0.459
J45.0 Predominantly allergic asthma	0.000	0.552	0.448
K90.9 Intestinal malabsorption, unspecified	0.000	0.564	0.436
L41 Parapsoriasis	0.425	0.575	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.577	0.423
E44.0 Moderate protein-energy malnutrition	0.000	0.577	0.423
L43 Lichen planus	0.418	0.582	0.000
L42 Pityriasis rosea	0.417	0.583	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.407	0.593	0.000
E14.9 Without complications	0.000	0.601	0.399
L44 Other papulosquamous disorders	0.396	0.604	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.396	0.604	0.000
J45.8 Mixed asthma	0.000	0.612	0.388
J45.1 Nonallergic asthma	0.000	0.612	0.388
I22.0 Subsequent myocardial infarction of anterior wall	0.365	0.635	0.000
E67 Other hyperalimentation	0.000	0.637	0.363
E68 Sequelae of hyperalimentation	0.000	0.637	0.363
E13.8 With unspecified complications	0.000	0.642	0.357
E13.7 With multiple complications	0.000	0.642	0.357
E13.6 With other specified complications	0.000	0.642	0.357
E13.5 With peripheral circulatory complications	0.000	0.642	0.357
E13.4 With neurological complications	0.000	0.642	0.357
E13.2 With renal complications	0.000	0.642	0.357
E13.1 With ketoacidosis	0.000	0.642	0.357
E13.0 With coma	0.000	0.642	0.357
L43.9 Lichen planus, unspecified	0.349	0.651	0.000
E06 Thyroiditis	0.001	0.660	0.340
E56 Other vitamin deficiencies	0.000	0.663	0.337
L41.1 Pityriasis lichenoides chronica	0.333	0.666	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.668	0.332
E63 Other nutritional deficiencies	0.000	0.668	0.332
E50 Vitamin A deficiency	0.000	0.668	0.332
E60 Dietary zinc deficiency	0.000	0.668	0.332
E59 Dietary selenium deficiency	0.000	0.668	0.332
E54 Ascorbic acid deficiency	0.000	0.668	0.332
E52 Niacin deficiency [pellagra]	0.000	0.668	0.332
E51 Thiamine deficiency	0.000	0.677	0.323
E53 Deficiency of other B group vitamins	0.000	0.682	0.318
E61 Deficiency of other nutrient elements	0.000	0.685	0.315
E13.3 With ophthalmic complications	0.000	0.688	0.311
I20 Angina pectoris	0.311	0.689	0.000
L41.9 Parapsoriasis, unspecified	0.305	0.695	0.000
L41.8 Other parapsoriasis	0.305	0.695	0.000
L41.5 Retiform parapsoriasis	0.305	0.695	0.000
L41.4 Large plaque parapsoriasis	0.305	0.695	0.000
L41.3 Small plaque parapsoriasis	0.305	0.695	0.000
L41.2 Lymphomatoid papulosis	0.305	0.695	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.305	0.695	0.000
L43.3 Subacute (active) lichen planus	0.300	0.700	0.000
L43.2 Lichenoid drug reaction	0.300	0.700	0.000
L43.1 Bullous lichen planus	0.300	0.700	0.000
L43.0 Hypertrophic lichen planus	0.300	0.700	0.000
E66 Obesity	0.000	0.700	0.300
E58 Dietary calcium deficiency	0.000	0.700	0.299
I21.4 Acute subendocardial myocardial infarction	0.292	0.708	0.000
L44.9 Papulosquamous disorder, unspecified	0.284	0.716	0.000
L44.8 Other specified papulosquamous disorders	0.284	0.716	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.284	0.716	0.000
L44.3 Lichen ruber moniliformis	0.284	0.716	0.000
L44.2 Lichen striatus	0.284	0.716	0.000
L44.1 Lichen nitidus	0.284	0.716	0.000
L44.0 Pityriasis rubra pilaris	0.284	0.716	0.000
E66.8 Other obesity	0.000	0.723	0.277
I20.1 Angina pectoris with documented spasm	0.273	0.727	0.000
C44.6 Skin of upper limb, including shoulder	0.265	0.735	0.000
E65 Localised adiposity	0.000	0.738	0.262
E67.8 Other specified hyperalimentation	0.000	0.739	0.260
E67.3 Hypervitaminosis D	0.000	0.739	0.260
E67.2 Megavitamin-B6 syndrome	0.000	0.739	0.260
E67.1 Hypercarotenaemia	0.000	0.739	0.260
E67.0 Hypervitaminosis A	0.000	0.739	0.260
L43.8 Other lichen planus	0.252	0.747	0.000
E56.1 Deficiency of vitamin K	0.000	0.753	0.247
E06.4 Drug-induced thyroiditis	0.001	0.756	0.244
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.756	0.244
E06.1 Subacute thyroiditis	0.001	0.756	0.244
E06.0 Acute thyroiditis	0.001	0.756	0.244
E56.9 Vitamin deficiency, unspecified	0.000	0.758	0.242
E56.8 Deficiency of other vitamins	0.000	0.758	0.242
E56.0 Deficiency of vitamin E	0.000	0.758	0.242
E61.2 Magnesium deficiency	0.000	0.759	0.241
E50.9 Vitamin A deficiency, unspecified	0.000	0.761	0.238
E50.8 Other manifestations of vitamin A deficiency	0.000	0.761	0.238
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.761	0.238
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.761	0.238
E50.5 Vitamin A deficiency with night blindness	0.000	0.761	0.238
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.761	0.238
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.761	0.238
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.761	0.238
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.761	0.238
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.761	0.238
E63.9 Nutritional deficiency, unspecified	0.000	0.761	0.238
E63.8 Other specified nutritional deficiencies	0.000	0.761	0.238
E63.1 Imbalance of constituents of food intake	0.000	0.761	0.238
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.761	0.238
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.761	0.238
E64.8 Sequelae of other nutritional deficiencies	0.000	0.761	0.238
E64.3 Sequelae of rickets	0.000	0.761	0.238
E64.2 Sequelae of vitamin C deficiency	0.000	0.761	0.238
E64.1 Sequelae of vitamin A deficiency	0.000	0.761	0.238
E64.0 Sequelae of protein-energy malnutrition	0.000	0.761	0.238
M07.39 Other psoriatic arthropathies (Site unspecified)	0.238	0.762	0.000
M07.3 Other psoriatic arthropathies	0.238	0.762	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.768	0.232
E51.8 Other manifestations of thiamine deficiency	0.000	0.768	0.232
E51.1 Beriberi	0.000	0.768	0.232
E53.8 Deficiency of other specified B group vitamins	0.000	0.770	0.230
M07.30 Other psoriatic arthropathies (Multiple sites)	0.229	0.771	0.000
E13.9 Without complications	0.000	0.771	0.228
E53.1 Pyridoxine deficiency	0.000	0.771	0.228
E53.0 Riboflavin deficiency	0.000	0.771	0.228
E55 Vitamin D deficiency	0.000	0.774	0.226
E61.9 Deficiency of nutrient element, unspecified	0.000	0.774	0.226
E61.8 Deficiency of other specified nutrient elements	0.000	0.774	0.226
E61.7 Deficiency of multiple nutrient elements	0.000	0.774	0.226
E61.6 Vanadium deficiency	0.000	0.774	0.226
E61.5 Molybdenum deficiency	0.000	0.774	0.226
E61.4 Chromium deficiency	0.000	0.774	0.226
E61.3 Manganese deficiency	0.000	0.774	0.226
E61.0 Copper deficiency	0.000	0.774	0.226
E51.2 Wernicke's encephalopathy	0.000	0.777	0.223
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.219	0.781	0.000
E06.5 Other chronic thyroiditis	0.001	0.782	0.218
E66.1 Drug-induced obesity	0.000	0.785	0.215
E53.9 Vitamin B deficiency, unspecified	0.000	0.787	0.212
M07.36 Other psoriatic arthropathies (Lower leg)	0.208	0.792	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.206	0.794	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.205	0.795	0.000
C82.0 Small cleaved cell, follicular	0.195	0.805	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.194	0.806	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.813	0.186
E61.1 Iron deficiency	0.000	0.815	0.185
E06.9 Thyroiditis, unspecified	0.001	0.818	0.181
M07.31 Other psoriatic arthropathies (Shoulder region)	0.176	0.823	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.175	0.825	0.000
M07.38 Other psoriatic arthropathies (Other)	0.171	0.829	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.171	0.829	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.171	0.829	0.000
C82.3 Follicular lymphoma grade IIIa	0.169	0.831	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.169	0.831	0.000
C82.2 Large cell, follicular	0.163	0.837	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.162	0.837	0.000
E66.0 Obesity due to excess calories	0.000	0.838	0.162
E55.0 Rickets, active	0.000	0.838	0.162
C82.1 Mixed small cleaved and large cell, follicular	0.157	0.843	0.000
C82.4 Follicular lymphoma grade IIIb	0.154	0.846	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.153	0.847	0.000
I20.0 Unstable angina	0.152	0.848	0.000
C82.6 Cutaneous follicle centre lymphoma	0.147	0.853	0.000
C82.5 Diffuse follicle centre lymphoma	0.147	0.853	0.000
I20.9 Angina pectoris, unspecified	0.140	0.860	0.000
N20.0 Calculus of kidney	0.119	0.881	0.000
N20 Calculus of kidney and ureter	0.117	0.883	0.000
E06.3 Autoimmune thyroiditis	0.001	0.885	0.114
N23 Unspecified renal colic	0.114	0.886	0.000
N20.1 Calculus of ureter	0.113	0.887	0.000
N20-N23 Urolithiasis	0.109	0.891	0.000
M07 Psoriatic and enteropathic arthropathies	0.100	0.899	0.001
E20-E35 Disorders of other endocrine glands	0.000	0.910	0.090
E22 Hyperfunction of pituitary gland	0.000	0.916	0.084
N22 Calculus of urinary tract in diseases classified elsewhere	0.078	0.922	0.000
I20.8 Other forms of angina pectoris	0.077	0.923	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.923	0.077
M07.6 Other enteropathic arthropathies	0.072	0.927	0.001
M07.5 Arthropathy in ulcerative colitis	0.072	0.927	0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.072	0.927	0.001
M07.2 Psoriatic spondylitis	0.072	0.927	0.001
M07.1 Arthritis mutilans	0.072	0.927	0.001
M07.0 Distal interphalangeal psoriatic arthropathy	0.072	0.927	0.001
I21.0 Acute transmural myocardial infarction of anterior wall	0.067	0.933	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.934	0.066
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.935	0.065
E32 Diseases of thymus	0.000	0.935	0.065
E30 Disorders of puberty, not elsewhere classified	0.000	0.935	0.065
E22.1 Hyperprolactinaemia	0.000	0.936	0.064
N20.9 Urinary calculus, unspecified	0.064	0.936	0.000
E31 Polyglandular dysfunction	0.000	0.937	0.062
N20.2 Calculus of kidney with calculus of ureter	0.062	0.938	0.000
E20 Hypoparathyroidism	0.000	0.938	0.062
E04 Other non-toxic goitre	0.001	0.938	0.061
E24 Cushing's syndrome	0.000	0.939	0.061
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.940	0.060
E22.8 Other hyperfunction of pituitary gland	0.000	0.940	0.060
E28 Ovarian dysfunction	0.000	0.941	0.059
E25 Adrenogenital disorders	0.000	0.942	0.058
E27 Other disorders of adrenal gland	0.000	0.943	0.057
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.056	0.944	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.056	0.944	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.944	0.056
E29 Testicular dysfunction	0.000	0.945	0.054
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.052	0.948	0.001
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.052	0.948	0.001
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.052	0.948	0.001
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.052	0.948	0.001
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.052	0.948	0.001
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.052	0.948	0.001
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.052	0.948	0.001
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.052	0.948	0.001
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.052	0.948	0.001
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.052	0.948	0.001
M07.19 Arthritis mutilans (Site unspecified)	0.052	0.948	0.001
M07.18 Arthritis mutilans (Other)	0.052	0.948	0.001
M07.17 Arthritis mutilans (Ankle and foot)	0.052	0.948	0.001
M07.16 Arthritis mutilans (Lower leg)	0.052	0.948	0.001
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.052	0.948	0.001
M07.14 Arthritis mutilans (Hand)	0.052	0.948	0.001
M07.13 Arthritis mutilans (Forearm)	0.052	0.948	0.001
M07.12 Arthritis mutilans (Upper arm)	0.052	0.948	0.001
M07.11 Arthritis mutilans (Shoulder region)	0.052	0.948	0.001
M07.10 Arthritis mutilans (Multiple sites)	0.052	0.948	0.001
M07.29 Psoriatic spondylitis (Site unspecified)	0.052	0.948	0.001
M07.28 Psoriatic spondylitis (Other)	0.052	0.948	0.001
M07.27 Psoriatic spondylitis (Ankle and foot)	0.052	0.948	0.001
M07.26 Psoriatic spondylitis (Lower leg)	0.052	0.948	0.001
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.052	0.948	0.001
M07.24 Psoriatic spondylitis (Hand)	0.052	0.948	0.001
M07.23 Psoriatic spondylitis (Forearm)	0.052	0.948	0.001
M07.22 Psoriatic spondylitis (Upper arm)	0.052	0.948	0.001
M07.21 Psoriatic spondylitis (Shoulder region)	0.052	0.948	0.001
M07.20 Psoriatic spondylitis (Multiple sites)	0.052	0.948	0.001
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.052	0.948	0.001
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.052	0.948	0.001
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.052	0.948	0.001
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.052	0.948	0.001
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.052	0.948	0.001
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.052	0.948	0.001
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.052	0.948	0.001
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.052	0.948	0.001
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.052	0.948	0.001
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.052	0.948	0.001
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.052	0.948	0.001
M07.58 Arthropathy in ulcerative colitis (Other)	0.052	0.948	0.001
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.052	0.948	0.001
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.052	0.948	0.001
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.052	0.948	0.001
M07.54 Arthropathy in ulcerative colitis (Hand)	0.052	0.948	0.001
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.052	0.948	0.001
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.052	0.948	0.001
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.052	0.948	0.001
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.052	0.948	0.001
M07.69 Other enteropathic arthropathies (Site unspecified)	0.052	0.948	0.001
M07.68 Other enteropathic arthropathies (Other)	0.052	0.948	0.001
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.052	0.948	0.001
M07.66 Other enteropathic arthropathies (Lower leg)	0.052	0.948	0.001
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.052	0.948	0.001
M07.64 Other enteropathic arthropathies (Hand)	0.052	0.948	0.001
M07.63 Other enteropathic arthropathies (Forearm)	0.052	0.948	0.001
M07.62 Other enteropathic arthropathies (Upper arm)	0.052	0.948	0.001
M07.61 Other enteropathic arthropathies (Shoulder region)	0.052	0.948	0.001
M07.60 Other enteropathic arthropathies (Multiple sites)	0.052	0.948	0.001
N21 Calculus of lower urinary tract	0.051	0.949	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.950	0.050
E28.3 Primary ovarian failure	0.000	0.951	0.048
E11 Non-insulin-dependent diabetes mellitus	0.000	0.952	0.048
E24.2 Drug-induced Cushing's syndrome	0.000	0.952	0.048
E30.9 Disorder of puberty, unspecified	0.000	0.953	0.046
E30.8 Other disorders of puberty	0.000	0.953	0.046
E30.1 Precocious puberty	0.000	0.953	0.046
E30.0 Delayed puberty	0.000	0.953	0.046
E32.9 Disease of thymus, unspecified	0.000	0.953	0.046
E32.8 Other diseases of thymus	0.000	0.953	0.046
E32.1 Abscess of thymus	0.000	0.953	0.046
E32.0 Persistent hyperplasia of thymus	0.000	0.953	0.046
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.953	0.046
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.953	0.046
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.953	0.046
E34 Other endocrine disorders	0.000	0.953	0.046
E66.9 Obesity, unspecified	0.000	0.954	0.046
E31.9 Polyglandular dysfunction, unspecified	0.000	0.955	0.045
E31.8 Other polyglandular dysfunction	0.000	0.955	0.045
E31.1 Polyglandular hyperfunction	0.000	0.955	0.045
E20.8 Other hypoparathyroidism	0.000	0.955	0.044
E20.1 Pseudohypoparathyroidism	0.000	0.955	0.044
E20.0 Idiopathic hypoparathyroidism	0.000	0.955	0.044
E27.8 Other specified disorders of adrenal gland	0.000	0.955	0.045
E04.8 Other specified non-toxic goitre	0.001	0.955	0.044
E24.8 Other Cushing's syndrome	0.000	0.956	0.044
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.956	0.044
E24.3 Ectopic ACTH syndrome	0.000	0.956	0.044
E24.1 Nelson's syndrome	0.000	0.956	0.044
E31.0 Autoimmune polyglandular failure	0.000	0.957	0.042
E28.9 Ovarian dysfunction, unspecified	0.000	0.957	0.042
E28.8 Other ovarian dysfunction	0.000	0.957	0.042
E28.1 Androgen excess	0.000	0.957	0.042
E28.0 Oestrogen excess	0.000	0.957	0.042
E25.9 Adrenogenital disorder, unspecified	0.000	0.958	0.042
E25.8 Other adrenogenital disorders	0.000	0.958	0.042
E20.9 Hypoparathyroidism, unspecified	0.000	0.958	0.041
E11.1 With ketoacidosis	0.000	0.959	0.041
E27.5 Adrenomedullary hyperfunction	0.000	0.959	0.041
E27.0 Other adrenocortical overactivity	0.000	0.959	0.041
K90-K93 Other diseases of the digestive system	0.000	0.959	0.041
C43 Malignant melanoma of skin	0.041	0.959	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.959	0.041
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.959	0.041
Z93.2 Ileostomy status	0.040	0.960	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.961	0.039
E29.8 Other testicular dysfunction	0.000	0.961	0.039
E29.0 Testicular hyperfunction	0.000	0.961	0.039
E24.9 Cushing's syndrome, unspecified	0.000	0.961	0.039
E26 Hyperaldosteronism	0.001	0.963	0.036
N21.9 Calculus of lower urinary tract, unspecified	0.037	0.963	0.000
N21.1 Calculus in urethra	0.035	0.964	0.000
N21.8 Other lower urinary tract calculus	0.035	0.965	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.965	0.035
E27.2 Addisonian crisis	0.000	0.965	0.034
E11.7 With multiple complications	0.000	0.965	0.035
E34.5 Androgen resistance syndrome	0.000	0.966	0.033
E34.4 Constitutional tall stature	0.000	0.966	0.033
E34.3 Short stature, not elsewhere classified	0.000	0.966	0.033
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.966	0.033
E34.1 Other hypersecretion of intestinal hormones	0.000	0.966	0.033
E27.9 Disorder of adrenal gland, unspecified	0.000	0.966	0.033
C43.3 Malignant melanoma of other and unspecified parts of face	0.033	0.967	0.000
C43.4 Malignant melanoma of scalp and neck	0.032	0.968	0.000
E34.8 Other specified endocrine disorders	0.000	0.969	0.030
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.970	0.030
E11.4 With neurological complications	0.000	0.970	0.030
E04.1 Non-toxic single thyroid nodule	0.000	0.970	0.030
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.970	0.030
C43.8 Overlapping malignant melanoma of skin	0.030	0.970	0.000
C43.0 Malignant melanoma of lip	0.030	0.970	0.000
E34.0 Carcinoid syndrome	0.000	0.971	0.029
E29.1 Testicular hypofunction	0.000	0.971	0.029
E11.6 With other specified complications	0.000	0.972	0.028
E34.9 Endocrine disorder, unspecified	0.000	0.972	0.028
L57.0 Actinic keratosis	0.028	0.972	0.000
E11.0 With coma	0.000	0.973	0.027
E26.8 Other hyperaldosteronism	0.001	0.973	0.026
E26.1 Secondary hyperaldosteronism	0.001	0.973	0.026
C43.7 Malignant melanoma of lower limb, including hip	0.027	0.973	0.000
E11.5 With peripheral circulatory complications	0.000	0.973	0.027
L57 Skin changes due to chronic exposure to nonionising radiation	0.026	0.974	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.026	0.974	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.974	0.026
E11.2 With renal complications	0.000	0.974	0.026
C43.2 Malignant melanoma of ear and external auricular canal	0.025	0.974	0.000
W19.9 Unspecified place	0.000	0.975	0.025
E28.2 Polycystic ovarian syndrome	0.000	0.976	0.024
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.024	0.976	0.000
E04.0 Non-toxic diffuse goitre	0.001	0.976	0.023
E11.8 With unspecified complications	0.000	0.976	0.024
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.976	0.023
C43.9 Malignant melanoma of skin, unspecified	0.023	0.977	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.023	0.977	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.022	0.978	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.978	0.022
E21.2 Other hyperparathyroidism	0.000	0.978	0.022
C43.6 Malignant melanoma of upper limb, including shoulder	0.022	0.978	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations