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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621367
log Bayes Factor = 107.163
Chromosome 6   position 32,768,721  (GRCh37) Explore rs2621367 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
I25 Chronic ischaemic heart disease
0.993 0.007 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.992 0.008 0.000
I20-I25 Ischaemic heart diseases
0.987 0.013 0.000
C44 Other malignant neoplasms of skin
0.986 0.014 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.014 0.986
C44.2 Skin of ear and external auricular canal
0.985 0.015 0.000
C44.7 Skin of lower limb, including hip
0.981 0.019 0.000
E10.4 With neurological complications
0.000 0.020 0.980
I21 Acute myocardial infarction
0.979 0.021 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.024 0.976
I25.9 Chronic ischaemic heart disease, unspecified
0.973 0.027 0.000
C44.3 Skin of other and unspecified parts of face
0.969 0.031 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.032 0.968
I21.2 Acute transmural myocardial infarction of other sites
0.962 0.038 0.000
I21.9 Acute myocardial infarction, unspecified
0.952 0.048 0.000
C44.4 Skin of scalp and neck
0.951 0.049 0.000
E10.2 With renal complications
0.000 0.061 0.939
I25.2 Old myocardial infarction
0.929 0.071 0.000
I24 Other acute ischaemic heart diseases
0.926 0.074 0.000
E10.8 With unspecified complications
0.000 0.091 0.909
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.100 0.900
I21.1 Acute transmural myocardial infarction of inferior wall
0.880 0.120 0.000
E07 Other disorders of thyroid
0.000 0.121 0.879
E10.0 With coma
0.000 0.136 0.864
I24.8 Other forms of acute ischaemic heart disease
0.856 0.144 0.000
E10.6 With other specified complications
0.000 0.148 0.852
L40.1 Generalised pustular psoriasis
0.843 0.157 0.000
I23 Certain current complications following acute myocardial infarction
0.841 0.159 0.000
E40-E46 Malnutrition
0.000 0.159 0.841
L40.0 Psoriasis vulgaris
0.838 0.162 0.000
E14 Unspecified diabetes mellitus
0.000 0.163 0.837
I22 Subsequent myocardial infarction
0.817 0.183 0.000
I25.3 Aneurysm of heart
0.816 0.184 0.000
L40.4 Guttate psoriasis
0.814 0.186 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.814 0.186 0.000
C44.5 Skin of trunk
0.794 0.206 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.781 0.219 0.000
L40.8 Other psoriasis
0.781 0.219 0.000
C44.0 Skin of lip
0.770 0.230 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.235 0.765
E10.5 With peripheral circulatory complications
0.000 0.240 0.760
E14.3 With ophthalmic complications
0.000 0.250 0.750
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.254 0.745
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.733 0.267 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.272 0.728
E03.1 Congenital hypothyroidism without goitre
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
C44.8 Overlapping lesion of skin
0.707 0.293 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.293 0.707
I21.X Presumed acute myicardial infaction (unconfirmed)
0.702 0.298 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.300 0.700
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.300 0.700
E16.4 Abnormal secretion of gastrin
0.000 0.300 0.700
E16.3 Increased secretion of glucagon
0.000 0.300 0.700
E07.8 Other specified disorders of thyroid
0.000 0.309 0.691
E14.8 With unspecified complications
0.000 0.311 0.688
C44.9 Malignant neoplasm of skin, unspecified
0.686 0.314 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.676 0.324 0.000
E03.8 Other specified hypothyroidism
0.000 0.350 0.650
J45 Asthma
0.000 0.355 0.645
L40.3 Pustulosis palmaris et plantaris
0.641 0.358 0.000
E07.1 Dyshormogenetic goitre
0.000 0.369 0.630
E07.0 Hypersecretion of calcitonin
0.000 0.369 0.630
I25.4 Coronary artery aneurysm
0.625 0.375 0.000
I24.1 Dressler's syndrome
0.625 0.375 0.000
E05.8 Other thyrotoxicosis
0.000 0.376 0.624
I23.8 Other current complications following acute myocardial infarction
0.612 0.388 0.000
E14.6 With other specified complications
0.000 0.392 0.608
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.603 0.397 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.603 0.397 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.603 0.397 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.603 0.397 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.603 0.397 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.603 0.397 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.397 0.603
E45 Retarded development following protein-energy malnutrition
0.000 0.397 0.603
E43 Unspecified severe protein-energy malnutrition
0.000 0.397 0.603
E42 Marasmic kwashiorkor
0.000 0.397 0.603
E41 Nutritional marasmus
0.000 0.397 0.603
E40 Kwashiorkor
0.000 0.397 0.603
E14.7 With multiple complications
0.000 0.400 0.600
E14.2 Withrenal complications
0.000 0.400 0.600
E14.0 With coma
0.000 0.400 0.600
K90 Intestinal malabsorption
0.000 0.401 0.599
E14.5 With peripheral circulatory complications
0.000 0.403 0.597
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.591 0.409 0.000
E14.1 With ketoacidosis
0.000 0.414 0.586
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.419 0.580
I25.0 Atherosclerotic cardiovascular disease, so described
0.574 0.425 0.000
J45.0 Predominantly allergic asthma
0.000 0.427 0.573
I22.8 Subsequent myocardial infarction of other sites
0.571 0.429 0.000
I25.5 Ischaemic cardiomyopathy
0.568 0.432 0.000
I25.1 Atherosclerotic heart disease
0.567 0.433 0.000
E50-E64 Other nutritional deficiencies
0.000 0.439 0.561
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.454 0.546
I22.0 Subsequent myocardial infarction of anterior wall
0.531 0.469 0.000
C44.1 Skin of eyelid, including canthus
0.530 0.470 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E14.9 Without complications
0.000 0.494 0.506
E65-E68 Obesity and other hyperalimentation
0.000 0.497 0.502
E14.4 With neurological complications
0.000 0.507 0.492
L40-L45 Papulosquamous disorders
0.491 0.509 0.000
E13 Other specified diabetes mellitus
0.000 0.514 0.486
K90.8 Other intestinal malabsorption
0.000 0.535 0.465
J45.8 Mixed asthma
0.000 0.537 0.463
J45.1 Nonallergic asthma
0.000 0.537 0.463
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.454 0.546 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.567 0.432
E44.0 Moderate protein-energy malnutrition
0.000 0.567 0.432
E53 Deficiency of other B group vitamins
0.000 0.569 0.430
K90.3 Pancreatic steatorrhoea
0.000 0.570 0.430
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.570 0.430
K90.1 Tropical sprue
0.000 0.570 0.430
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.428 0.572 0.000
C82.0 Small cleaved cell, follicular
0.409 0.591 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.597 0.402
E63 Other nutritional deficiencies
0.000 0.597 0.402
E56 Other vitamin deficiencies
0.000 0.597 0.402
E50 Vitamin A deficiency
0.000 0.597 0.402
E60 Dietary zinc deficiency
0.000 0.597 0.402
E59 Dietary selenium deficiency
0.000 0.597 0.402
E54 Ascorbic acid deficiency
0.000 0.597 0.402
E52 Niacin deficiency [pellagra]
0.000 0.597 0.402
E61 Deficiency of other nutrient elements
0.000 0.599 0.401
I20 Angina pectoris
0.401 0.599 0.000
E51 Thiamine deficiency
0.000 0.601 0.399
K90.9 Intestinal malabsorption, unspecified
0.000 0.617 0.383
L41 Parapsoriasis
0.370 0.630 0.000
L42 Pityriasis rosea
0.364 0.635 0.000
C44.6 Skin of upper limb, including shoulder
0.362 0.638 0.000
E67 Other hyperalimentation
0.000 0.639 0.360
E68 Sequelae of hyperalimentation
0.000 0.639 0.360
E58 Dietary calcium deficiency
0.000 0.645 0.355
E53.8 Deficiency of other specified B group vitamins
0.000 0.647 0.353
L43 Lichen planus
0.352 0.648 0.000
L44 Other papulosquamous disorders
0.352 0.648 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.352 0.648 0.000
C82.2 Large cell, follicular
0.350 0.650 0.000
E13.8 With unspecified complications
0.000 0.651 0.348
E13.7 With multiple complications
0.000 0.651 0.348
E13.6 With other specified complications
0.000 0.651 0.348
E13.5 With peripheral circulatory complications
0.000 0.651 0.348
E13.4 With neurological complications
0.000 0.651 0.348
E13.2 With renal complications
0.000 0.651 0.348
E13.1 With ketoacidosis
0.000 0.651 0.348
E13.0 With coma
0.000 0.651 0.348
C82.3 Follicular lymphoma grade IIIa
0.343 0.657 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.332 0.668 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.328 0.672 0.000
E06 Thyroiditis
0.001 0.674 0.325
E66 Obesity
0.000 0.681 0.319
C82.4 Follicular lymphoma grade IIIb
0.319 0.681 0.000
I20.1 Angina pectoris with documented spasm
0.313 0.687 0.000
E53.1 Pyridoxine deficiency
0.000 0.691 0.309
E53.0 Riboflavin deficiency
0.000 0.691 0.309
C82.6 Cutaneous follicle centre lymphoma
0.307 0.693 0.000
C82.5 Diffuse follicle centre lymphoma
0.307 0.693 0.000
E13.3 With ophthalmic complications
0.001 0.700 0.299
E61.2 Magnesium deficiency
0.000 0.701 0.299
E66.8 Other obesity
0.000 0.703 0.297
E50.9 Vitamin A deficiency, unspecified
0.000 0.711 0.289
E50.8 Other manifestations of vitamin A deficiency
0.000 0.711 0.289
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.711 0.289
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.711 0.289
E50.5 Vitamin A deficiency with night blindness
0.000 0.711 0.289
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.711 0.289
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.711 0.289
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.711 0.289
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.711 0.289
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.711 0.289
E56.9 Vitamin deficiency, unspecified
0.000 0.711 0.289
E56.8 Deficiency of other vitamins
0.000 0.711 0.289
E56.1 Deficiency of vitamin K
0.000 0.711 0.289
E56.0 Deficiency of vitamin E
0.000 0.711 0.289
E63.9 Nutritional deficiency, unspecified
0.000 0.711 0.289
E63.8 Other specified nutritional deficiencies
0.000 0.711 0.289
E63.1 Imbalance of constituents of food intake
0.000 0.711 0.289
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.711 0.289
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.711 0.289
E64.8 Sequelae of other nutritional deficiencies
0.000 0.711 0.289
E64.3 Sequelae of rickets
0.000 0.711 0.289
E64.2 Sequelae of vitamin C deficiency
0.000 0.711 0.289
E64.1 Sequelae of vitamin A deficiency
0.000 0.711 0.289
E64.0 Sequelae of protein-energy malnutrition
0.000 0.711 0.289
E61.9 Deficiency of nutrient element, unspecified
0.000 0.712 0.287
E61.8 Deficiency of other specified nutrient elements
0.000 0.712 0.287
E61.7 Deficiency of multiple nutrient elements
0.000 0.712 0.287
E61.6 Vanadium deficiency
0.000 0.712 0.287
E61.5 Molybdenum deficiency
0.000 0.712 0.287
E61.4 Chromium deficiency
0.000 0.712 0.287
E61.3 Manganese deficiency
0.000 0.712 0.287
E61.0 Copper deficiency
0.000 0.712 0.287
I20.0 Unstable angina
0.287 0.713 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.714 0.286
E51.8 Other manifestations of thiamine deficiency
0.000 0.714 0.286
E51.1 Beriberi
0.000 0.714 0.286
E53.9 Vitamin B deficiency, unspecified
0.000 0.717 0.283
E51.2 Wernicke's encephalopathy
0.000 0.717 0.283
L41.1 Pityriasis lichenoides chronica
0.283 0.717 0.000
L43.9 Lichen planus, unspecified
0.283 0.717 0.000
E55 Vitamin D deficiency
0.000 0.723 0.277
E61.1 Iron deficiency
0.000 0.728 0.272
I21.4 Acute subendocardial myocardial infarction
0.268 0.732 0.000
L41.9 Parapsoriasis, unspecified
0.265 0.735 0.000
L41.8 Other parapsoriasis
0.265 0.735 0.000
L41.5 Retiform parapsoriasis
0.265 0.735 0.000
L41.4 Large plaque parapsoriasis
0.265 0.735 0.000
L41.3 Small plaque parapsoriasis
0.265 0.735 0.000
L41.2 Lymphomatoid papulosis
0.265 0.735 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.265 0.735 0.000
E67.8 Other specified hyperalimentation
0.000 0.741 0.258
E67.3 Hypervitaminosis D
0.000 0.741 0.258
E67.2 Megavitamin-B6 syndrome
0.000 0.741 0.258
E67.1 Hypercarotenaemia
0.000 0.741 0.258
E67.0 Hypervitaminosis A
0.000 0.741 0.258
L43.3 Subacute (active) lichen planus
0.253 0.747 0.000
L43.2 Lichenoid drug reaction
0.253 0.747 0.000
L43.1 Bullous lichen planus
0.253 0.747 0.000
L43.0 Hypertrophic lichen planus
0.253 0.747 0.000
L44.9 Papulosquamous disorder, unspecified
0.253 0.747 0.000
L44.8 Other specified papulosquamous disorders
0.253 0.747 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.253 0.747 0.000
L44.3 Lichen ruber moniliformis
0.253 0.747 0.000
L44.2 Lichen striatus
0.253 0.747 0.000
L44.1 Lichen nitidus
0.253 0.747 0.000
L44.0 Pityriasis rubra pilaris
0.253 0.747 0.000
E06.4 Drug-induced thyroiditis
0.001 0.766 0.233
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.766 0.233
E06.1 Subacute thyroiditis
0.001 0.766 0.233
E06.0 Acute thyroiditis
0.001 0.766 0.233
E66.1 Drug-induced obesity
0.000 0.771 0.229
E65 Localised adiposity
0.000 0.773 0.227
I22.9 Subsequent myocardial infarction of unspecified site
0.222 0.778 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.217 0.783 0.000
E13.9 Without complications
0.000 0.784 0.215
E06.5 Other chronic thyroiditis
0.001 0.785 0.214
L43.8 Other lichen planus
0.210 0.790 0.000
I20.9 Angina pectoris, unspecified
0.206 0.794 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.800 0.200
E55.0 Rickets, active
0.000 0.801 0.199
M07.39 Other psoriatic arthropathies (Site unspecified)
0.189 0.811 0.000
M07.3 Other psoriatic arthropathies
0.188 0.812 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.180 0.820 0.000
E66.0 Obesity due to excess calories
0.000 0.823 0.177
M07.36 Other psoriatic arthropathies (Lower leg)
0.164 0.836 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.163 0.837 0.000
E06.9 Thyroiditis, unspecified
0.001 0.837 0.162
M07.34 Other psoriatic arthropathies (Hand)
0.153 0.847 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.140 0.860 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.138 0.862 0.000
M07.38 Other psoriatic arthropathies (Other)
0.135 0.865 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.135 0.865 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.135 0.865 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.115 0.885 0.000
E06.3 Autoimmune thyroiditis
0.001 0.900 0.099
T43.2 Other and unspecified antidepressants
0.090 0.910 0.000
T42.4 Benzodiazepines
0.088 0.912 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.086 0.914 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.086 0.914 0.000
I20.8 Other forms of angina pectoris
0.082 0.918 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.080 0.920 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.080 0.920 0.000
M07 Psoriatic and enteropathic arthropathies
0.079 0.920 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.079 0.921 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.076 0.924 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.926 0.074
T50.9 Other and unspecified drugs, medicaments and biological substances
0.073 0.927 0.000
W19.9 Unspecified place
0.000 0.930 0.070
T42.3 Barbiturates
0.069 0.931 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.069 0.931 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.065 0.935 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.063 0.937 0.000
T42.0 Hydantoin derivatives
0.063 0.937 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.062 0.938 0.000
T43.9 Psychotropic drug, unspecified
0.062 0.938 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.062 0.938 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.061 0.938 0.000
T42.2 Succinimides and oxazolidinediones
0.061 0.938 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.061 0.939 0.000
E04 Other non-toxic goitre
0.001 0.939 0.060
T42.1 Iminostilbenes
0.060 0.940 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.060 0.940 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.059 0.941 0.000
E66.9 Obesity, unspecified
0.000 0.941 0.059
T36 Poisoning by systemic antibiotics
0.058 0.942 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.058 0.942 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.058 0.942 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.058 0.942 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.057 0.943 0.000
M07.6 Other enteropathic arthropathies
0.057 0.943 0.000
M07.5 Arthropathy in ulcerative colitis
0.057 0.943 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.057 0.943 0.000
M07.2 Psoriatic spondylitis
0.057 0.943 0.000
M07.1 Arthritis mutilans
0.057 0.943 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.057 0.943 0.000
C43 Malignant melanoma of skin
0.057 0.943 0.000
T50.7 Analeptics and opioid receptor antagonists
0.054 0.945 0.000
T50.5 Appetite depressants
0.054 0.945 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.054 0.945 0.000
T50.1 Loop [high-ceiling] diuretics
0.054 0.945 0.000
T50.0 Mineralocorticoids and their antagonists
0.054 0.945 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.054 0.946 0.000
T50.4 Drugs affecting uric acid metabolism
0.053 0.947 0.000
T50.8 Diagnostic agents
0.052 0.947 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.052 0.947 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.052 0.948 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.052 0.948 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.049 0.951 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.048 0.952 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.047 0.953 0.000
T43.6 Psychostimulants with abuse potential
0.047 0.953 0.000
T47.2 Stimulant laxatives
0.047 0.953 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.046 0.954 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.046 0.954 0.000
C43.4 Malignant melanoma of scalp and neck
0.046 0.954 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.045 0.955 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.045 0.955 0.000
T47.7 Emetics
0.045 0.955 0.000
T47.6 Antidiarrhoeal drugs
0.045 0.955 0.000
T47.5 Digestants
0.045 0.955 0.000
T47.4 Other laxatives
0.045 0.955 0.000
T47.3 Saline and osmotic laxatives
0.045 0.955 0.000
T47.0 Histamine H(2)-receptor antagonists
0.045 0.955 0.000
T36.3 Macrolides
0.045 0.955 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.045 0.955 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.045 0.955 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.045 0.955 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.045 0.955 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.045 0.955 0.000
T44.0 Anticholinesterase agents
0.045 0.955 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.045 0.955 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.044 0.956 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.044 0.956 0.000
T45.0 Antiallergic and antiemetic drugs
0.044 0.956 0.000
E04.8 Other specified non-toxic goitre
0.001 0.956 0.043
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.043 0.957 0.000
T48.5 Anti-common-cold drugs
0.043 0.957 0.000
T48.4 Expectorants
0.043 0.957 0.000
T48.3 Antitussives
0.043 0.957 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.043 0.957 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.043 0.957 0.000
T48.0 Oxytocic drugs
0.043 0.957 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.043 0.957 0.000
T37.5 Antiviral drugs
0.043 0.957 0.000
T37.4 Anthelminthics
0.043 0.957 0.000
T37.3 Other antiprotozoal drugs
0.043 0.957 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.043 0.957 0.000
T37.1 Antimycobacterial drugs
0.043 0.957 0.000
T37.0 Sulphonamides
0.043 0.957 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.042 0.957 0.000
T36.9 Systemic antibiotic, unspecified
0.042 0.958 0.000
T36.8 Other systemic antibiotics
0.042 0.958 0.000
T36.7 Antifungal antibiotics, systemically used
0.042 0.958 0.000
T36.6 Rifamycins
0.042 0.958 0.000
T36.5 Aminoglycosides
0.042 0.958 0.000
T36.4 Tetracyclines
0.042 0.958 0.000
T36.2 Chloramphenicol group
0.042 0.958 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.042 0.958 0.000
T41.5 Therapeutic gases
0.042 0.958 0.000
T41.4 Anaesthetic, unspecified
0.042 0.958 0.000
T41.3 Local anaesthetics
0.042 0.958 0.000
T41.2 Other and unspecified general anaesthetics
0.042 0.958 0.000
T41.1 Intravenous anaesthetics
0.042 0.958 0.000
T41.0 Inhaled anaesthetics
0.042 0.958 0.000
T49.9 Topical agent, unspecified
0.042 0.958 0.000
T49.8 Other topical agents
0.042 0.958 0.000
T49.7 Dental drugs, topically applied
0.042 0.958 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.042 0.958 0.000
T49.5 Ophthalmological drugs and preparations
0.042 0.958 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.042 0.958 0.000
T49.3 Emollients, demulcents and protectants
0.042 0.958 0.000
T49.2 Local astringents and local detergents
0.042 0.958 0.000
T49.1 Antipruritics
0.042 0.958 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.042 0.958 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.041 0.959 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.041 0.959 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.041 0.959 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.041 0.959 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.041 0.959 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.041 0.959 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.041 0.959 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.041 0.959 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.041 0.959 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.041 0.959 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.041 0.959 0.000
M07.18 Arthritis mutilans (Other)
0.041 0.959 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.041 0.959 0.000
M07.16 Arthritis mutilans (Lower leg)
0.041 0.959 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.041 0.959 0.000
M07.14 Arthritis mutilans (Hand)
0.041 0.959 0.000
M07.13 Arthritis mutilans (Forearm)
0.041 0.959 0.000
M07.12 Arthritis mutilans (Upper arm)
0.041 0.959 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.041 0.959 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.041 0.959 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.041 0.959 0.000
M07.28 Psoriatic spondylitis (Other)
0.041 0.959 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.041 0.959 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.041 0.959 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.041 0.959 0.000
M07.24 Psoriatic spondylitis (Hand)
0.041 0.959 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.041 0.959 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.041 0.959 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.041 0.959 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.041 0.959 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.041 0.959 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.041 0.959 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.041 0.959 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.041 0.959 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.041 0.959 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.041 0.959 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.041 0.959 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.041 0.959 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.041 0.959 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.041 0.959 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.041 0.959 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.041 0.959 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.041 0.959 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.041 0.959 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.041 0.959 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.041 0.959 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.041 0.959 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.041 0.959 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.041 0.959 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.041 0.959 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.041 0.959 0.000
M07.68 Other enteropathic arthropathies (Other)
0.041 0.959 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.041 0.959 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.041 0.959 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.041 0.959 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.041 0.959 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.041 0.959 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.041 0.959 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.041 0.959 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.041 0.959 0.000
L57.0 Actinic keratosis
0.041 0.959 0.000
C43.8 Overlapping malignant melanoma of skin
0.041 0.959 0.000
C43.0 Malignant melanoma of lip
0.041 0.959 0.000
E20-E35 Disorders of other endocrine glands
0.001 0.960 0.040
T38.1 Thyroid hormones and substitutes
0.039 0.960 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.039 0.961 0.000
T45.8 Other primarily systemic and haematological agents
0.039 0.961 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.039 0.961 0.000
T45.6 Fibrinolysis-affecting drugs
0.039 0.961 0.000
T45.4 Iron and its compounds
0.039 0.961 0.000
T45.3 Enzymes, not elsewhere classified
0.039 0.961 0.000
K90-K93 Other diseases of the digestive system
0.000 0.961 0.039
L57 Skin changes due to chronic exposure to nonionising radiation
0.039 0.961 0.000
T36.0 Penicillins
0.038 0.962 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.038 0.962 0.000
T38.9 Other and unspecified hormone antagonists
0.037 0.963 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.037 0.963 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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