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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621391
log Bayes Factor = 50.0119
Chromosome 6   position 32,757,158  (GRCh37) Explore rs2621391 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.004 0.996
C44.6 Skin of upper limb, including shoulder
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
G35-G37 Demyelinating diseases of the central nervous system
0.990 0.010 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.010 0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E23 Hypofunction and other disorders of pituitary gland
0.000 0.012 0.988
G37 Other demyelinating diseases of central nervous system
0.987 0.013 0.000
E10.9 Without complications
0.000 0.014 0.986
E83.1 Disorders of iron metabolism
0.985 0.015 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.981 0.019 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.020 0.980
E11 Non-insulin-dependent diabetes mellitus
0.000 0.025 0.975
L40-L45 Papulosquamous disorders
0.000 0.033 0.967
E70-E90 Metabolic disorders
0.000 0.040 0.960
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.041 0.959
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.053 0.947
E11.3 With ophthalmic complications
0.000 0.064 0.936
E78.0 Pure hypercholesterolaemia
0.000 0.066 0.934
E23.6 Other disorders of pituitary gland
0.000 0.070 0.930
E23.7 Disorder of pituitary gland, unspecified
0.000 0.075 0.925
C44.2 Skin of ear and external auricular canal
0.000 0.079 0.921
C44.4 Skin of scalp and neck
0.000 0.080 0.920
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.082 0.918
E27 Other disorders of adrenal gland
0.000 0.094 0.906
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.104 0.896
E11.9 Without complications
0.000 0.108 0.892
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.109 0.891
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.114 0.886
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.114 0.886
C44.0 Skin of lip
0.000 0.116 0.884
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
G37.8 Other specified demyelinating diseases of central nervous system
0.881 0.119 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.121 0.879
L43 Lichen planus
0.000 0.127 0.873
E78.5 Hyperlipidaemia, unspecified
0.000 0.129 0.871
E06 Thyroiditis
0.000 0.131 0.868
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.134 0.866
E10.1 With ketoacidosis
0.000 0.141 0.859
E04 Other non-toxic goitre
0.000 0.148 0.852
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.153 0.847
E23.2 Diabetes insipidus
0.000 0.159 0.841
E27.1 Primary adrenocortical insufficiency
0.000 0.160 0.840
M06.0 Seronegative rheumatoid arthritis
0.000 0.162 0.838
E10.0 With coma
0.000 0.162 0.838
E89.0 Postprocedural hypothyroidism
0.000 0.173 0.827
E11.2 With renal complications
0.000 0.174 0.826
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.175 0.825
E78.2 Mixed hyperlipidaemia
0.000 0.183 0.817
E06.3 Autoimmune thyroiditis
0.000 0.188 0.812
M10 Gout
0.000 0.189 0.811
E28 Ovarian dysfunction
0.000 0.189 0.811
E78.6 Lipoprotein deficiency
0.000 0.191 0.809
G36 Other acute disseminated demyelination
0.802 0.198 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
L40.0 Psoriasis vulgaris
0.000 0.198 0.802
M06.3 Rheumatoid nodule
0.000 0.198 0.802
E78.1 Pure hyperglyceridaemia
0.000 0.212 0.788
E10.2 With renal complications
0.000 0.214 0.786
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.215 0.785
E23.0 Hypopituitarism
0.000 0.219 0.781
E24 Cushing's syndrome
0.000 0.222 0.778
E13 Other specified diabetes mellitus
0.000 0.228 0.772
M06.4 Inflammatory polyarthropathy
0.000 0.231 0.768
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.233 0.767
E29 Testicular dysfunction
0.000 0.235 0.765
E04.0 Non-toxic diffuse goitre
0.000 0.237 0.763
L43.8 Other lichen planus
0.000 0.243 0.757
E11.1 With ketoacidosis
0.000 0.250 0.750
D00-D09 In situ neoplasms
0.000 0.252 0.748
E26 Hyperaldosteronism
0.000 0.253 0.747
E88 Other metabolic disorders
0.000 0.255 0.745
Chapter II Neoplasms
0.000 0.255 0.745
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.256 0.744
D04 Carcinoma in situ of skin
0.000 0.260 0.740
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.261 0.739
E10.8 With unspecified complications
0.000 0.265 0.735
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.266 0.734
D06 Carcinoma in situ of cervix uteri
0.000 0.266 0.734
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.267 0.733
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.268 0.732
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.269 0.731
L43.9 Lichen planus, unspecified
0.000 0.270 0.730
L40.4 Guttate psoriasis
0.000 0.270 0.730
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.275 0.725
E84 Cystic fibrosis
0.000 0.275 0.725
D06.9 Cervix, unspecified
0.000 0.276 0.724
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.276 0.724
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.281 0.719
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.713
E32 Diseases of thymus
0.000 0.286 0.713
E31 Polyglandular dysfunction
0.000 0.286 0.713
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.713
E10.6 With other specified complications
0.000 0.287 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
E04.2 Non-toxic multinodular goitre
0.000 0.288 0.712
E11.0 With coma
0.000 0.288 0.712
E89.3 Postprocedural hypopituitarism
0.000 0.291 0.709
E11.8 With unspecified complications
0.000 0.291 0.708
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.292 0.708
E05.8 Other thyrotoxicosis
0.000 0.292 0.708
G37.5 Concentric sclerosis [Balo]
0.708 0.292 0.000
G37.4 Subacute necrotising myelitis
0.708 0.292 0.000
G37.2 Central pontine myelinolysis
0.708 0.292 0.000
G37.1 Central demyelination of corpus callosum
0.708 0.292 0.000
G37.0 Diffuse sclerosis
0.708 0.292 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.293 0.707
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.293 0.707
L42 Pityriasis rosea
0.000 0.297 0.703
E79 Disorders of purine and pyrimidine metabolism
0.000 0.299 0.700
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.300 0.700
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.301 0.699
E11.7 With multiple complications
0.000 0.301 0.699
E03.8 Other specified hypothyroidism
0.000 0.301 0.699
L44 Other papulosquamous disorders
0.000 0.307 0.693
L41 Parapsoriasis
0.000 0.307 0.693
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.307 0.693
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
C83.3 Large cell (diffuse)
0.000 0.310 0.690
E77 Disorders of glycoprotein metabolism
0.000 0.312 0.688
E76 Disorders of glycosaminoglycan metabolism
0.000 0.312 0.688
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.312 0.688
E70 Disorders of aromatic amino-acid metabolism
0.000 0.312 0.688
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.312 0.688
E28.2 Polycystic ovarian syndrome
0.000 0.316 0.684
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.682
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.318 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
D04.5 Skin of trunk
0.000 0.321 0.679
L57.5 Actinic granuloma
0.000 0.321 0.679
L57.3 Poikiloderma of Civatte
0.000 0.321 0.679
L57.2 Cutis rhomboidalis nuchae
0.000 0.321 0.679
L57.1 Actinic reticuloid
0.000 0.321 0.679
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.322 0.678
E20 Hypoparathyroidism
0.000 0.322 0.677
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.327 0.673
C43 Malignant melanoma of skin
0.000 0.327 0.673
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.328 0.672
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.328 0.672
E11.6 With other specified complications
0.000 0.332 0.668
G36.0 Neuromyelitis optica [Devic]
0.668 0.332 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.333 0.667
M12 Other specific arthropathies
0.000 0.333 0.666
E10.4 With neurological complications
0.000 0.336 0.664
E89.4 Postprocedural ovarian failure
0.000 0.338 0.662
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.342 0.658
L55 Sunburn
0.000 0.342 0.658
E04.9 Non-toxic goitre, unspecified
0.000 0.342 0.658
E25 Adrenogenital disorders
0.000 0.344 0.656
E78.4 Other hyperlipidaemia
0.000 0.345 0.655
C85.1 B-cell lymphoma, unspecified
0.000 0.345 0.655
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.348 0.652
E27.9 Disorder of adrenal gland, unspecified
0.000 0.348 0.652
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.348 0.652
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.349 0.651
E27.5 Adrenomedullary hyperfunction
0.000 0.350 0.650
E27.0 Other adrenocortical overactivity
0.000 0.350 0.650
L82 Seborrhoeic keratosis
0.000 0.354 0.646
M10.0 Idiopathic gout
0.000 0.356 0.644
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.359 0.641
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.361 0.639
E89.5 Postprocedural testicular hypofunction
0.000 0.361 0.639
M10.9 Gout, unspecified
0.000 0.362 0.638
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.363 0.637
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.364 0.635
D04.7 Skin of lower limb, including hip
0.000 0.365 0.635
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.367 0.633
M05.2 Rheumatoid vasculitis
0.000 0.370 0.630
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.370 0.630
D43.0 Brain, supratentorial
0.000 0.373 0.627
L43.3 Subacute (active) lichen planus
0.000 0.374 0.626
L43.2 Lichenoid drug reaction
0.000 0.374 0.626
L43.1 Bullous lichen planus
0.000 0.374 0.626
L43.0 Hypertrophic lichen planus
0.000 0.374 0.626
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.375 0.625
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.376 0.624
E06.5 Other chronic thyroiditis
0.000 0.377 0.623
E06.4 Drug-induced thyroiditis
0.000 0.377 0.623
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.377 0.623
E06.0 Acute thyroiditis
0.000 0.377 0.623
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.622
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.379 0.621
M11 Other crystal arthropathies
0.000 0.379 0.621
E06.9 Thyroiditis, unspecified
0.000 0.381 0.619
D09 Carcinoma in situ of other and unspecified sites
0.000 0.382 0.618
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.382 0.618
C73 Malignant neoplasm of thyroid gland
0.000 0.383 0.617
E89.1 Postprocedural hypoinsulinaemia
0.000 0.383 0.617
E89.2 Postprocedural hypoparathyroidism
0.000 0.386 0.613
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.387 0.613
E78.3 Hyperchylomicronaemia
0.000 0.389 0.611
E04.8 Other specified non-toxic goitre
0.000 0.389 0.611
M06.34 Rheumatoid nodule (Hand)
0.000 0.390 0.610
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.391 0.609
E13.9 Without complications
0.000 0.391 0.609
E21.3 Hyperparathyroidism, unspecified
0.000 0.391 0.609
E88.8 Other specified metabolic disorders
0.000 0.393 0.607
L58 Radiodermatitis
0.000 0.396 0.604
E27.8 Other specified disorders of adrenal gland
0.000 0.398 0.602
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.399 0.601
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.399 0.601
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.399 0.601
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.399 0.601
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.399 0.601
E29.1 Testicular hypofunction
0.000 0.399 0.601
E11.5 With peripheral circulatory complications
0.000 0.399 0.601
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.401 0.599
L85 Other epidermal thickening
0.000 0.402 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.402 0.598
M14 Arthropathies in other diseases classified elsewhere
0.000 0.403 0.597
E24.0 Pituitary-dependent Cushing's disease
0.000 0.404 0.596
E74 Other disorders of carbohydrate metabolism
0.000 0.404 0.596
D04.2 Skin of ear and external auricular canal
0.000 0.405 0.595
D04.4 Skin of scalp and neck
0.000 0.405 0.595
C91 Lymphoid leukaemia
0.000 0.407 0.593
D46 Myelodysplastic syndromes
0.000 0.408 0.592
E73 Lactose intolerance
0.000 0.408 0.592
E72 Other disorders of amino-acid metabolism
0.000 0.410 0.589
E24.9 Cushing's syndrome, unspecified
0.000 0.414 0.586
L94 Other localised connective tissue disorders
0.000 0.414 0.586
E80.4 Gilbert's syndrome
0.000 0.415 0.585
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.416 0.584
M10.4 Other secondary gout
0.000 0.418 0.582
M10.2 Drug-induced gout
0.000 0.418 0.582
M10.1 Lead-induced gout
0.000 0.418 0.582
E28.9 Ovarian dysfunction, unspecified
0.000 0.418 0.582
E28.8 Other ovarian dysfunction
0.000 0.418 0.582
E28.1 Androgen excess
0.000 0.418 0.582
E28.0 Oestrogen excess
0.000 0.418 0.582
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.420 0.580
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.423 0.577
D04.9 Skin, unspecified
0.000 0.423 0.577
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.424 0.576
G36.9 Acute disseminated demyelination, unspecified
0.575 0.425 0.000
G36.8 Other specified acute disseminated demyelination
0.575 0.425 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.575 0.425 0.000
E85 Amyloidosis
0.000 0.425 0.575
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.425 0.575
M06.38 Rheumatoid nodule (Other)
0.000 0.425 0.575
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.425 0.575
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.425 0.575
M06.33 Rheumatoid nodule (Forearm)
0.000 0.425 0.575
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.425 0.575
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.425 0.575
L10-L14 Bullous disorders
0.000 0.426 0.574
E28.3 Primary ovarian failure
0.000 0.426 0.574
L85.8 Other specified epidermal thickening
0.000 0.428 0.572
E26.0 Primary hyperaldosteronism
0.000 0.431 0.569
E88.2 Lipomatosis, not elsewhere classified
0.000 0.431 0.569
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.434 0.566
E88.9 Metabolic disorder, unspecified
0.000 0.434 0.566
M10.3 Gout due to impairment of renal function
0.000 0.435 0.565
E21.0 Primary hyperparathyroidism
0.000 0.435 0.565
E21.4 Other specified disorders of parathyroid gland
0.000 0.437 0.563
E24.2 Drug-induced Cushing's syndrome
0.000 0.439 0.561
L57.4 Cutis laxa senilis
0.000 0.440 0.560
E24.8 Other Cushing's syndrome
0.000 0.442 0.558
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.442 0.558
E24.3 Ectopic ACTH syndrome
0.000 0.442 0.558
E24.1 Nelson's syndrome
0.000 0.442 0.558
E84.9 Cystic fibrosis, unspecified
0.000 0.443 0.557
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.3 With ophthalmic complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.446 0.553
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.447 0.553
C83.1 Small cleaved cell (diffuse)
0.000 0.448 0.552
C82.0 Small cleaved cell, follicular
0.000 0.448 0.552
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.449 0.551
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.449 0.551
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.449 0.551
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.449 0.551
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.449 0.551
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.449 0.551
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.449 0.551
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.449 0.551
M10.90 Gout, unspecified (Multiple sites)
0.000 0.449 0.551
C83.7 Burkitt's tumour
0.000 0.451 0.549
E21.2 Other hyperparathyroidism
0.000 0.451 0.549
E29.9 Testicular dysfunction, unspecified
0.000 0.451 0.549
E29.8 Other testicular dysfunction
0.000 0.451 0.549
E29.0 Testicular hyperfunction
0.000 0.451 0.549
E78.8 Other disorders of lipoprotein metabolism
0.000 0.453 0.546
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.454 0.546
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.459 0.541
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.461 0.539
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.461 0.539
D47.1 Chronic myeloproliferative disease
0.000 0.462 0.538
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.462 0.538
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.463 0.537
D47.2 Monoclonal gammopathy
0.000 0.463 0.537
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.463 0.536
E26.9 Hyperaldosteronism, unspecified
0.000 0.464 0.535
E26.8 Other hyperaldosteronism
0.000 0.464 0.535
E26.1 Secondary hyperaldosteronism
0.000 0.464 0.535
E80.6 Other disorders of bilirubin metabolism
0.000 0.466 0.534
E88.3 Tumour lysis syndrome
0.000 0.466 0.534
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.466 0.534
C94 Other leukaemias of specified cell type
0.000 0.466 0.534
E80.1 Porphyria cutanea tarda
0.000 0.469 0.531
D03 Melanoma in situ
0.000 0.469 0.531
D06.0 Endocervix
0.000 0.469 0.531
D04.8 Skin of other sites
0.000 0.469 0.530
D04.0 Skin of lip
0.000 0.469 0.530
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.470 0.530
C85.0 Lymphosarcoma
0.000 0.470 0.530
M13 Other arthritis
0.000 0.472 0.528
L56.3 Solar urticaria
0.000 0.474 0.526
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.474 0.526
L56.1 Drug photoallergic response
0.000 0.474 0.526
L56.0 Drug phototoxic response
0.000 0.474 0.526
D06.7 Other parts of cervix
0.000 0.474 0.526
D06.1 Exocervix
0.000 0.474 0.526
L94.2 Calcinosis cutis
0.000 0.476 0.524
M10.09 Idiopathic gout (Site unspecified)
0.000 0.476 0.524
C12 Malignant neoplasm of pyriform sinus
0.000 0.478 0.522
E40-E46 Malnutrition
0.000 0.478 0.521
C91.9 Lymphoid leukaemia, unspecified
0.000 0.478 0.521
C86 Other specified types of T/NK-cell lymphoma
0.000 0.479 0.520
E84.8 Cystic fibrosis with other manifestations
0.000 0.480 0.520
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.480 0.520
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.480 0.520
C93 Monocytic leukaemia
0.000 0.480 0.520
C44.5 Skin of trunk
0.000 0.482 0.518
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.484 0.516
E80.5 Crigler-Najjar syndrome
0.000 0.484 0.516
E80.3 Defects of catalase and peroxydase
0.000 0.484 0.516
E80.0 Hereditary erythropoietic porphyria
0.000 0.484 0.516
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.486 0.514
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.486 0.514
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.486 0.514
M07.28 Psoriatic spondylitis (Other)
0.000 0.486 0.514
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.486 0.514
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.486 0.514
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.24 Psoriatic spondylitis (Hand)
0.000 0.486 0.514
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.486 0.514
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.486 0.514
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.486 0.514
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.486 0.514
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.486 0.514
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.486 0.514
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.486 0.514
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.486 0.514
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.486 0.514
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.486 0.514
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.486 0.514
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.486 0.514
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.486 0.514
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.486 0.514
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.486 0.514
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.486 0.514
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.486 0.514
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.486 0.514
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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