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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621393
log Bayes Factor = 50.1894
Chromosome 6   position 32,755,216  (GRCh37) Explore rs2621393 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.002 0.998
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
C44.6 Skin of upper limb, including shoulder
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
C44.3 Skin of other and unspecified parts of face
0.000 0.006 0.994
E23 Hypofunction and other disorders of pituitary gland
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
E10.9 Without complications
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
G35-G37 Demyelinating diseases of the central nervous system
0.989 0.011 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.014 0.986
E83.1 Disorders of iron metabolism
0.986 0.014 0.000
G37 Other demyelinating diseases of central nervous system
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.016 0.984
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.019 0.981
G37.9 Demyelinating disease of central nervous system, unspecified
0.978 0.022 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.035 0.965
L40-L45 Papulosquamous disorders
0.000 0.039 0.961
E11 Non-insulin-dependent diabetes mellitus
0.000 0.045 0.955
E27 Other disorders of adrenal gland
0.000 0.048 0.952
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.055 0.945
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.058 0.942
E23.6 Other disorders of pituitary gland
0.000 0.065 0.935
E23.7 Disorder of pituitary gland, unspecified
0.000 0.070 0.930
C44.2 Skin of ear and external auricular canal
0.000 0.073 0.927
E78.5 Hyperlipidaemia, unspecified
0.000 0.075 0.925
C44.4 Skin of scalp and neck
0.000 0.078 0.922
E11.3 With ophthalmic complications
0.000 0.080 0.920
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.089 0.911
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.090 0.910
E27.1 Primary adrenocortical insufficiency
0.000 0.096 0.904
D00-D09 In situ neoplasms
0.000 0.104 0.896
Chapter II Neoplasms
0.000 0.104 0.896
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.105 0.895
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.113 0.887
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.113 0.887
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.113 0.887
C44.0 Skin of lip
0.000 0.114 0.886
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.114 0.886
E10.5 With peripheral circulatory complications
0.000 0.118 0.882
D06 Carcinoma in situ of cervix uteri
0.000 0.119 0.881
D04 Carcinoma in situ of skin
0.000 0.119 0.881
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.120 0.880
G37.8 Other specified demyelinating diseases of central nervous system
0.879 0.121 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.125 0.875
E23.2 Diabetes insipidus
0.000 0.129 0.871
D06.9 Cervix, unspecified
0.000 0.130 0.870
E06 Thyroiditis
0.000 0.130 0.870
E10.1 With ketoacidosis
0.000 0.139 0.861
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.142 0.858
E78.2 Mixed hyperlipidaemia
0.000 0.143 0.857
L43 Lichen planus
0.000 0.150 0.850
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.151 0.849
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.158 0.842
C83.3 Large cell (diffuse)
0.000 0.159 0.841
E10.0 With coma
0.000 0.161 0.839
E11.9 Without complications
0.000 0.162 0.838
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.162 0.838
E89.0 Postprocedural hypothyroidism
0.000 0.163 0.837
E78.6 Lipoprotein deficiency
0.000 0.169 0.831
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
E28 Ovarian dysfunction
0.000 0.177 0.822
L40.0 Psoriasis vulgaris
0.000 0.181 0.819
E23.0 Hypopituitarism
0.000 0.184 0.816
E04 Other non-toxic goitre
0.000 0.185 0.815
E06.3 Autoimmune thyroiditis
0.000 0.186 0.814
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.188 0.812
D04.5 Skin of trunk
0.000 0.191 0.809
E78.1 Pure hyperglyceridaemia
0.000 0.191 0.809
M10 Gout
0.000 0.192 0.808
C85.1 B-cell lymphoma, unspecified
0.000 0.192 0.808
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.196 0.804
M06.3 Rheumatoid nodule
0.000 0.197 0.803
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
G36 Other acute disseminated demyelination
0.801 0.199 0.000
E29 Testicular dysfunction
0.000 0.211 0.789
M06.0 Seronegative rheumatoid arthritis
0.000 0.212 0.788
E10.2 With renal complications
0.000 0.213 0.787
E88 Other metabolic disorders
0.000 0.214 0.786
E11.2 With renal complications
0.000 0.214 0.786
D04.3 Skin of other and unspecified parts of face
0.000 0.217 0.783
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.218 0.782
E24 Cushing's syndrome
0.000 0.226 0.774
E13 Other specified diabetes mellitus
0.000 0.226 0.774
D43.0 Brain, supratentorial
0.000 0.228 0.772
C73 Malignant neoplasm of thyroid gland
0.000 0.229 0.771
M06.4 Inflammatory polyarthropathy
0.000 0.231 0.769
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.231 0.769
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.232 0.768
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.234 0.766
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.235 0.765
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.239 0.761
D09 Carcinoma in situ of other and unspecified sites
0.000 0.248 0.751
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.255 0.745
E84 Cystic fibrosis
0.000 0.257 0.743
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.258 0.742
E26 Hyperaldosteronism
0.000 0.258 0.742
E11.1 With ketoacidosis
0.000 0.265 0.735
E10.8 With unspecified complications
0.000 0.265 0.735
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.265 0.735
E89.3 Postprocedural hypopituitarism
0.000 0.267 0.733
E04.0 Non-toxic diffuse goitre
0.000 0.270 0.730
L40.4 Guttate psoriasis
0.000 0.270 0.730
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.271 0.729
C91 Lymphoid leukaemia
0.000 0.273 0.727
D46 Myelodysplastic syndromes
0.000 0.273 0.727
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.274 0.726
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.274 0.726
D04.7 Skin of lower limb, including hip
0.000 0.276 0.724
E79 Disorders of purine and pyrimidine metabolism
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
L42 Pityriasis rosea
0.000 0.284 0.716
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.286 0.714
L43.8 Other lichen planus
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.286 0.714
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.288 0.712
E23.1 Drug-induced hypopituitarism
0.000 0.288 0.712
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.289 0.711
D04.2 Skin of ear and external auricular canal
0.000 0.291 0.709
L43.9 Lichen planus, unspecified
0.000 0.291 0.709
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.291 0.709
D04.4 Skin of scalp and neck
0.000 0.291 0.709
E05.8 Other thyrotoxicosis
0.000 0.292 0.708
C43 Malignant melanoma of skin
0.000 0.294 0.706
G37.5 Concentric sclerosis [Balo]
0.706 0.294 0.000
G37.4 Subacute necrotising myelitis
0.706 0.294 0.000
G37.2 Central pontine myelinolysis
0.706 0.294 0.000
G37.1 Central demyelination of corpus callosum
0.706 0.294 0.000
G37.0 Diffuse sclerosis
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.294 0.705
E76 Disorders of glycosaminoglycan metabolism
0.000 0.294 0.705
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.294 0.705
E70 Disorders of aromatic amino-acid metabolism
0.000 0.294 0.705
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.294 0.705
E27.9 Disorder of adrenal gland, unspecified
0.000 0.298 0.702
E28.2 Polycystic ovarian syndrome
0.000 0.300 0.700
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.301 0.699
E11.0 With coma
0.000 0.302 0.698
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.304 0.696
E11.8 With unspecified complications
0.000 0.306 0.694
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.308 0.692
L44 Other papulosquamous disorders
0.000 0.311 0.689
L41 Parapsoriasis
0.000 0.311 0.689
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.311 0.689
E03.8 Other specified hypothyroidism
0.000 0.311 0.688
D04.9 Skin, unspecified
0.000 0.313 0.687
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.314 0.686
E11.7 With multiple complications
0.000 0.315 0.684
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.317 0.683
E27.5 Adrenomedullary hyperfunction
0.000 0.317 0.683
E27.0 Other adrenocortical overactivity
0.000 0.317 0.683
E03.1 Congenital hypothyroidism without goitre
0.000 0.317 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E20 Hypoparathyroidism
0.000 0.320 0.680
M06.8 Other specified rheumatoid arthritis
0.000 0.321 0.679
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.322 0.678
L57.5 Actinic granuloma
0.000 0.322 0.678
L57.3 Poikiloderma of Civatte
0.000 0.322 0.678
L57.2 Cutis rhomboidalis nuchae
0.000 0.322 0.678
L57.1 Actinic reticuloid
0.000 0.322 0.678
E89.4 Postprocedural ovarian failure
0.000 0.324 0.676
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.326 0.674
E78.4 Other hyperlipidaemia
0.000 0.326 0.673
C82.0 Small cleaved cell, follicular
0.000 0.328 0.672
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.329 0.671
C83.1 Small cleaved cell (diffuse)
0.000 0.329 0.671
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.330 0.670
C83.7 Burkitt's tumour
0.000 0.333 0.667
M12 Other specific arthropathies
0.000 0.333 0.667
G36.0 Neuromyelitis optica [Devic]
0.667 0.333 0.000
E10.4 With neurological complications
0.000 0.333 0.667
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.335 0.665
D03 Melanoma in situ
0.000 0.336 0.664
D47.1 Chronic myeloproliferative disease
0.000 0.336 0.663
D47.2 Monoclonal gammopathy
0.000 0.337 0.662
E25 Adrenogenital disorders
0.000 0.341 0.658
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.343 0.657
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.343 0.657
L55 Sunburn
0.000 0.346 0.653
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.348 0.652
E89.5 Postprocedural testicular hypofunction
0.000 0.348 0.652
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.348 0.652
E04.9 Non-toxic goitre, unspecified
0.000 0.348 0.652
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.651 0.349 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.356 0.644
M10.0 Idiopathic gout
0.000 0.358 0.642
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.358 0.642
C94 Other leukaemias of specified cell type
0.000 0.358 0.642
E88.8 Other specified metabolic disorders
0.000 0.360 0.640
C91.9 Lymphoid leukaemia, unspecified
0.000 0.361 0.639
E29.1 Testicular hypofunction
0.000 0.362 0.638
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.362 0.638
D06.0 Endocervix
0.000 0.363 0.637
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.364 0.636
C85.0 Lymphosarcoma
0.000 0.364 0.636
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.365 0.635
E27.8 Other specified disorders of adrenal gland
0.000 0.366 0.634
M10.9 Gout, unspecified
0.000 0.368 0.632
D06.7 Other parts of cervix
0.000 0.368 0.632
D06.1 Exocervix
0.000 0.368 0.632
D04.8 Skin of other sites
0.000 0.368 0.632
D04.0 Skin of lip
0.000 0.368 0.632
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.369 0.631
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.369 0.631
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.369 0.631
M05.2 Rheumatoid vasculitis
0.000 0.370 0.630
E89.1 Postprocedural hypoinsulinaemia
0.000 0.370 0.630
D09.0 Bladder
0.000 0.372 0.628
C12 Malignant neoplasm of pyriform sinus
0.000 0.372 0.628
E78.3 Hyperchylomicronaemia
0.000 0.373 0.627
E89.2 Postprocedural hypoparathyroidism
0.000 0.373 0.627
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.373 0.627
C86 Other specified types of T/NK-cell lymphoma
0.000 0.374 0.626
C93 Monocytic leukaemia
0.000 0.375 0.625
E06.5 Other chronic thyroiditis
0.000 0.376 0.624
E06.4 Drug-induced thyroiditis
0.000 0.376 0.624
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.376 0.624
E06.0 Acute thyroiditis
0.000 0.376 0.624
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.378 0.622
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.622
M11 Other crystal arthropathies
0.000 0.378 0.622
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.379 0.621
E06.9 Thyroiditis, unspecified
0.000 0.379 0.621
C88 Malignant immunoproliferative diseases
0.000 0.381 0.619
E80.4 Gilbert's syndrome
0.000 0.382 0.618
D43.2 Brain, unspecified
0.000 0.383 0.617
E11.6 With other specified complications
0.000 0.383 0.617
C83.6 Undifferentiated (diffuse)
0.000 0.385 0.615
C83.5 Lymphoblastic (diffuse)
0.000 0.385 0.615
C83.4 Immunoblastic (diffuse)
0.000 0.385 0.615
C83.2 Mixed small and large cell (diffuse)
0.000 0.385 0.615
D48.5 Skin
0.000 0.387 0.613
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.388 0.612
E13.9 Without complications
0.000 0.388 0.612
E74 Other disorders of carbohydrate metabolism
0.000 0.389 0.611
M06.34 Rheumatoid nodule (Hand)
0.000 0.389 0.611
C07 Malignant neoplasm of parotid gland
0.000 0.390 0.610
E04.2 Non-toxic multinodular goitre
0.000 0.390 0.610
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.390 0.609
L43.3 Subacute (active) lichen planus
0.000 0.391 0.609
L43.2 Lichenoid drug reaction
0.000 0.391 0.609
L43.1 Bullous lichen planus
0.000 0.391 0.609
L43.0 Hypertrophic lichen planus
0.000 0.391 0.609
E73 Lactose intolerance
0.000 0.392 0.608
D43.4 Spinal cord
0.000 0.395 0.605
E72 Other disorders of amino-acid metabolism
0.000 0.395 0.604
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.399 0.601
E88.2 Lipomatosis, not elsewhere classified
0.000 0.400 0.600
L58 Radiodermatitis
0.000 0.401 0.599
D46.2 Refractory anaemia with excess of blasts
0.000 0.401 0.599
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.401 0.598
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.403 0.597
E88.9 Metabolic disorder, unspecified
0.000 0.403 0.597
E27.2 Addisonian crisis
0.000 0.405 0.594
E24.0 Pituitary-dependent Cushing's disease
0.000 0.406 0.594
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.407 0.593
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.407 0.593
C03 Malignant neoplasm of gum
0.000 0.408 0.592
D01.0 Colon
0.000 0.408 0.592
C82.2 Large cell, follicular
0.000 0.409 0.591
C02.9 Tongue, unspecified
0.000 0.409 0.591
E21.3 Hyperparathyroidism, unspecified
0.000 0.409 0.591
E85 Amyloidosis
0.000 0.409 0.591
E28.9 Ovarian dysfunction, unspecified
0.000 0.410 0.590
E28.8 Other ovarian dysfunction
0.000 0.410 0.590
E28.1 Androgen excess
0.000 0.410 0.590
E28.0 Oestrogen excess
0.000 0.410 0.590
C81 Hodgkin's disease
0.000 0.415 0.585
E04.8 Other specified non-toxic goitre
0.000 0.416 0.584
E28.3 Primary ovarian failure
0.000 0.418 0.582
C95 Leukaemia of unspecified cell type
0.000 0.419 0.581
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.419 0.581
M10.4 Other secondary gout
0.000 0.420 0.580
M10.2 Drug-induced gout
0.000 0.420 0.580
M10.1 Lead-induced gout
0.000 0.420 0.580
D40.0 Prostate
0.000 0.421 0.579
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.423 0.577
D43.9 Central nervous system, unspecified
0.000 0.424 0.576
D43.7 Other parts of central nervous system
0.000 0.424 0.576
D43.3 Cranial nerves
0.000 0.424 0.576
E24.9 Cushing's syndrome, unspecified
0.000 0.424 0.576
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.424 0.575
M06.38 Rheumatoid nodule (Other)
0.000 0.424 0.575
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.424 0.575
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.424 0.575
M06.33 Rheumatoid nodule (Forearm)
0.000 0.424 0.575
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.424 0.575
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.424 0.575
G36.9 Acute disseminated demyelination, unspecified
0.574 0.425 0.000
G36.8 Other specified acute disseminated demyelination
0.574 0.425 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.574 0.425 0.000
C02.1 Border of tongue
0.000 0.425 0.575
D09.1 Other and unspecified urinary organs
0.000 0.427 0.573
E84.9 Cystic fibrosis, unspecified
0.000 0.429 0.571
E21.0 Primary hyperparathyroidism
0.000 0.429 0.571
C91.5 Adult T-cell leukaemia
0.000 0.430 0.569
L10-L14 Bullous disorders
0.000 0.432 0.568
M14 Arthropathies in other diseases classified elsewhere
0.000 0.433 0.567
E29.9 Testicular dysfunction, unspecified
0.000 0.434 0.565
E29.8 Other testicular dysfunction
0.000 0.434 0.565
E29.0 Testicular hyperfunction
0.000 0.434 0.565
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.435 0.565
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.435 0.565
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.435 0.565
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.435 0.565
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.435 0.565
D43.1 Brain, infratentorial
0.000 0.436 0.564
E88.3 Tumour lysis syndrome
0.000 0.437 0.563
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.437 0.563
M10.3 Gout due to impairment of renal function
0.000 0.437 0.563
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.437 0.563
E78.8 Other disorders of lipoprotein metabolism
0.000 0.437 0.562
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.439 0.561
E21.4 Other specified disorders of parathyroid gland
0.000 0.439 0.560
L57.4 Cutis laxa senilis
0.000 0.440 0.559
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.441 0.559
E24.2 Drug-induced Cushing's syndrome
0.000 0.441 0.559
C91.4 Hairy-cell leukaemia
0.000 0.441 0.559
D03.5 Melanoma in situ of trunk
0.000 0.441 0.558
E26.0 Primary hyperaldosteronism
0.000 0.442 0.558
D04.6 Skin of upper limb, including shoulder
0.000 0.442 0.558
C11 Malignant neoplasm of nasopharynx
0.000 0.442 0.558
E11.5 With peripheral circulatory complications
0.000 0.442 0.558
E24.8 Other Cushing's syndrome
0.000 0.445 0.555
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.445 0.555
E24.3 Ectopic ACTH syndrome
0.000 0.445 0.555
E24.1 Nelson's syndrome
0.000 0.445 0.555
E13.8 With unspecified complications
0.000 0.445 0.555
E13.7 With multiple complications
0.000 0.445 0.555
E13.6 With other specified complications
0.000 0.445 0.555
E13.5 With peripheral circulatory complications
0.000 0.445 0.555
E13.4 With neurological complications
0.000 0.445 0.555
E13.3 With ophthalmic complications
0.000 0.445 0.555
E13.2 With renal complications
0.000 0.445 0.555
E13.1 With ketoacidosis
0.000 0.445 0.555
E13.0 With coma
0.000 0.445 0.555
D04.1 Skin of eyelid, including canthus
0.000 0.445 0.555
M10.90 Gout, unspecified (Multiple sites)
0.000 0.447 0.553
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.449 0.551
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.449 0.551
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.449 0.551
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.449 0.551
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.449 0.551
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.449 0.551
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.449 0.551
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.449 0.551
D00.1 Oesophagus
0.000 0.449 0.551
E80.1 Porphyria cutanea tarda
0.000 0.450 0.550
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.451 0.549
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.451 0.549
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.451 0.549
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.451 0.549
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.452 0.548
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.452 0.547
E21.2 Other hyperparathyroidism
0.000 0.453 0.547
C13 Malignant neoplasm of hypopharynx
0.000 0.454 0.546
E80.6 Other disorders of bilirubin metabolism
0.000 0.454 0.546
C82.6 Cutaneous follicle centre lymphoma
0.000 0.454 0.545
C82.5 Diffuse follicle centre lymphoma
0.000 0.454 0.545
C82.4 Follicular lymphoma grade IIIb
0.000 0.454 0.545
D46.7 Other myelodysplastic syndromes
0.000 0.456 0.544
C84.5 Other and unspecified T-cell lymphomas
0.000 0.457 0.543
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.459 0.541
D44.1 Adrenal gland
0.000 0.460 0.539
C91.0 Acute lymphoblastic leukaemia
0.000 0.461 0.539
C04 Malignant neoplasm of floor of mouth
0.000 0.461 0.539
D09.9 Carcinoma in situ, unspecified
0.000 0.461 0.539
D09.7 Carcinoma in situ of other specified sites
0.000 0.461 0.539
D09.3 Thyroid and other endocrine glands
0.000 0.461 0.539
D09.2 Eye
0.000 0.461 0.539
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.461 0.539
D44.4 Craniopharyngeal duct
0.000 0.462 0.537
D46.4 Refractory anaemia, unspecified
0.000 0.463 0.536
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.464 0.536
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.465 0.535
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.465 0.535
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.465 0.534
E80.5 Crigler-Najjar syndrome
0.000 0.465 0.534
E80.3 Defects of catalase and peroxydase
0.000 0.465 0.534
E80.0 Hereditary erythropoietic porphyria
0.000 0.465 0.534
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.467 0.533
E84.8 Cystic fibrosis with other manifestations
0.000 0.467 0.533
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.467 0.533
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.467 0.533
L82 Seborrhoeic keratosis
0.000 0.467 0.533
E26.9 Hyperaldosteronism, unspecified
0.000 0.468 0.532
E26.8 Other hyperaldosteronism
0.000 0.468 0.532
E26.1 Secondary hyperaldosteronism
0.000 0.468 0.532
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.472 0.527
D40.1 Testis
0.000 0.475 0.525
D46.1 Refractory anaemia with sideroblasts
0.000 0.477 0.523
L56.3 Solar urticaria
0.000 0.477 0.523
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.477 0.523
L56.1 Drug photoallergic response
0.000 0.477 0.523
L56.0 Drug phototoxic response
0.000 0.477 0.523
M10.09 Idiopathic gout (Site unspecified)
0.000 0.478 0.522
E40-E46 Malnutrition
0.000 0.478 0.522
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.478 0.522
C91.7 Other lymphoid leukaemia
0.000 0.478 0.522
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.478 0.522
C91.3 Prolymphocytic leukaemia
0.000 0.478 0.522
C91.2 Subacute lymphocytic leukaemia
0.000 0.478 0.522
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.479 0.521
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.479 0.521
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.479 0.521
D01.3 Anus and anal canal
0.000 0.483 0.516
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.485 0.515
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.485 0.515
E79.1 Lesch-Nyhan syndrome
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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