TreeWAS – Variant ID: rs2622604

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M10.99 Gout, unspecified (Site unspecified)	0.000	0.000	1.000
M10.9 Gout, unspecified	0.000	0.059	0.941
M10.94 Gout, unspecified (Hand)	0.000	0.151	0.849
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.172	0.828
M10.96 Gout, unspecified (Lower leg)	0.000	0.173	0.827
M10.93 Gout, unspecified (Forearm)	0.000	0.219	0.781
M10.98 Gout, unspecified (Other)	0.000	0.326	0.674
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.326	0.674
M10.91 Gout, unspecified (Shoulder region)	0.000	0.326	0.674
M10.90 Gout, unspecified (Multiple sites)	0.000	0.411	0.589
M10.92 Gout, unspecified (Upper arm)	0.000	0.470	0.530
M10 Gout	0.000	0.625	0.375
M10.4 Other secondary gout	0.000	0.731	0.269
M10.3 Gout due to impairment of renal function	0.000	0.731	0.269
M10.2 Drug-induced gout	0.000	0.731	0.269
M10.1 Lead-induced gout	0.000	0.731	0.269
M10.0 Idiopathic gout	0.000	0.740	0.260
M10.19 Lead-induced gout (Site unspecified)	0.000	0.807	0.193
M10.18 Lead-induced gout (Other)	0.000	0.807	0.193
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.807	0.193
M10.16 Lead-induced gout (Lower leg)	0.000	0.807	0.193
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.807	0.193
M10.14 Lead-induced gout (Hand)	0.000	0.807	0.193
M10.13 Lead-induced gout (Forearm)	0.000	0.807	0.193
M10.12 Lead-induced gout (Upper arm)	0.000	0.807	0.193
M10.11 Lead-induced gout (Shoulder region)	0.000	0.807	0.193
M10.10 Lead-induced gout (Multiple sites)	0.000	0.807	0.193
M10.29 Drug-induced gout (Site unspecified)	0.000	0.807	0.193
M10.28 Drug-induced gout (Other)	0.000	0.807	0.193
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.807	0.193
M10.26 Drug-induced gout (Lower leg)	0.000	0.807	0.193
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.807	0.193
M10.24 Drug-induced gout (Hand)	0.000	0.807	0.193
M10.23 Drug-induced gout (Forearm)	0.000	0.807	0.193
M10.22 Drug-induced gout (Upper arm)	0.000	0.807	0.193
M10.21 Drug-induced gout (Shoulder region)	0.000	0.807	0.193
M10.20 Drug-induced gout (Multiple sites)	0.000	0.807	0.193
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.807	0.193
M10.38 Gout due to impairment of renal function (Other)	0.000	0.807	0.193
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.807	0.193
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.807	0.193
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.807	0.193
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.807	0.193
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.807	0.193
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.807	0.193
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.807	0.193
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.807	0.193
M10.49 Other secondary gout (Site unspecified)	0.000	0.807	0.193
M10.48 Other secondary gout (Other)	0.000	0.807	0.193
M10.47 Other secondary gout (Ankle and foot)	0.000	0.807	0.193
M10.46 Other secondary gout (Lower leg)	0.000	0.807	0.193
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.807	0.193
M10.44 Other secondary gout (Hand)	0.000	0.807	0.193
M10.43 Other secondary gout (Forearm)	0.000	0.807	0.193
M10.42 Other secondary gout (Upper arm)	0.000	0.807	0.193
M10.41 Other secondary gout (Shoulder region)	0.000	0.807	0.193
M10.40 Other secondary gout (Multiple sites)	0.000	0.807	0.193
M10.09 Idiopathic gout (Site unspecified)	0.000	0.813	0.186
M10.08 Idiopathic gout (Other)	0.000	0.813	0.186
M10.06 Idiopathic gout (Lower leg)	0.000	0.813	0.186
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.813	0.186
M10.04 Idiopathic gout (Hand)	0.000	0.813	0.186
M10.03 Idiopathic gout (Forearm)	0.000	0.813	0.186
M10.02 Idiopathic gout (Upper arm)	0.000	0.813	0.186
M10.01 Idiopathic gout (Shoulder region)	0.000	0.813	0.186
M10.00 Idiopathic gout (Multiple sites)	0.000	0.813	0.186
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.823	0.177
L98.0 Pyogenic granuloma	0.038	0.962	0.000
H40.0 Glaucoma suspect	0.000	0.971	0.029
H40 Glaucoma	0.000	0.975	0.025
H40.2 Primary angle-closure glaucoma	0.000	0.976	0.024
H40.1 Primary open-angle glaucoma	0.000	0.978	0.022
H40.4 Glaucoma secondary to eye inflammation	0.000	0.979	0.020
H40.5 Glaucoma secondary to other eye disorders	0.000	0.980	0.020
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.019	0.981	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.982	0.018
H40.8 Other glaucoma	0.000	0.982	0.018
L98.4 Chronic ulcer of skin, not elsewhere classified	0.017	0.983	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.983	0.016
L98.1 Factitial dermatitis	0.016	0.984	0.000
C90.0 Multiple myeloma	0.015	0.985	0.000
H40.9 Glaucoma, unspecified	0.000	0.986	0.014
L98.7 Excessive and redundant skin and subcutaneous tissue	0.013	0.986	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.013	0.986	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.013	0.986	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.013	0.986	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.013	0.987	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.987	0.013
L98.5 Mucinosis of skin	0.012	0.988	0.000
H40-H42 Glaucoma	0.000	0.989	0.011
D37.4 Colon	0.000	0.989	0.011
Q51.3 Bicornate uterus	0.010	0.990	0.000
Q54 Hypospadias	0.009	0.991	0.000
Q50-Q56 Congenital malformations of genital organs	0.009	0.991	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.991	0.009
M54.39 Sciatica (Site unspecified)	0.009	0.991	0.000
Q51 Congenital malformations of uterus and cervix	0.009	0.991	0.000
Q53 Undescended testicle	0.009	0.991	0.000
Q54.0 Hypospadias, balanic	0.008	0.991	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.992	0.008
Q53.1 Undescended testicle, unilateral	0.008	0.992	0.000
Q54.9 Hypospadias, unspecified	0.008	0.992	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.008	0.992	0.000
H42 Glaucoma in diseases classified elsewhere	0.000	0.992	0.008
Q54.1 Hypospadias, penile	0.008	0.992	0.000
C15.9 Oesophagus, unspecified	0.000	0.993	0.007
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.993	0.007
Q52 Other congenital malformations of female genitalia	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.000	0.993	0.007
D37.0 Lip, oral cavity and pharynx	0.000	0.993	0.007
Q54.8 Other hypospadias	0.007	0.993	0.000
Q54.4 Congenital chordee	0.007	0.993	0.000
Q54.3 Hypospadias, perineal	0.007	0.993	0.000
Q54.2 Hypospadias, penoscrotal	0.007	0.993	0.000
Q51.2 Other doubling of uterus	0.007	0.993	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.007	0.993	0.000
C90.2 Plasmacytoma, extramedullary	0.007	0.993	0.000
E05.5 Thyroid crisis or storm	0.000	0.993	0.007
E05.4 Thyrotoxicosis factitia	0.000	0.993	0.007
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.993	0.007
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.993	0.007
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.007	0.993	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.007	0.993	0.000
Q51.6 Embryonic cyst of cervix	0.007	0.993	0.000
Q51.5 Agenesis and aplasia of cervix	0.007	0.993	0.000
Q51.4 Unicornate uterus	0.007	0.993	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.007	0.993	0.000
Q51.0 Agenesis and aplasia of uterus	0.007	0.993	0.000
E06 Thyroiditis	0.000	0.993	0.007
Q55 Other congenital malformations of male genital organs	0.006	0.993	0.000
Q53.9 Undescended testicle, unspecified	0.006	0.994	0.000
Q53.2 Undescended testicle, bilateral	0.006	0.994	0.000
Q53.0 Ectopic testis	0.006	0.994	0.000
E00-E07 Disorders of thyroid gland	0.000	0.994	0.006
D37.6 Liver, gallbladder and bile ducts	0.000	0.994	0.006
C90.1 Plasma cell leukaemia	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
M54.37 Sciatica (Lumbosacral region)	0.006	0.994	0.000
D37.3 Appendix	0.000	0.994	0.006
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.994	0.006
E05.8 Other thyrotoxicosis	0.000	0.994	0.006
R19.5 Other fecal abnormalities	0.000	0.994	0.006
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.006	0.994	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.994	0.006
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
M54.3 Sciatica	0.006	0.994	0.000
Q44.6 Cystic disease of liver	0.006	0.994	0.000
Q52.1 Doubling of vagina	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
Q52.5 Fusion of labia	0.006	0.994	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.994	0.006
D37.2 Small intestine	0.000	0.994	0.006
D37.1 Stomach	0.000	0.994	0.006
Q38-Q45 Other congenital malformations of the digestive system	0.006	0.994	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.005	0.994	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.005	0.994	0.000
Q52.7 Other congenital malformations of vulva	0.005	0.994	0.000
Q52.6 Congenital malformation of clitoris	0.005	0.994	0.000
Q52.4 Other congenital malformations of vagina	0.005	0.994	0.000
Q52.3 Imperforate hymen	0.005	0.994	0.000
Q52.2 Congenital rectovaginal fistula	0.005	0.994	0.000
Q52.0 Congenital absence of vagina	0.005	0.994	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.005	0.994	0.000
C90.3 Solitary plasmacytoma	0.005	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.994	0.000
Z36.8 Other antenatal screening	0.005	0.995	0.000
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
D37.7 Other digestive organs	0.000	0.995	0.005
Q56.4 Indeterminate sex, unspecified	0.005	0.995	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.005	0.995	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.005	0.995	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.005	0.995	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.005	0.995	0.000
D45 Polycythaemia vera	0.000	0.995	0.005
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.995	0.005
Q44.5 Other congenital malformations of bile ducts	0.005	0.995	0.000
E06.4 Drug-induced thyroiditis	0.000	0.995	0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.995	0.005
E06.1 Subacute thyroiditis	0.000	0.995	0.005
E06.0 Acute thyroiditis	0.000	0.995	0.005
Q44.7 Other congenital malformations of liver	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.005	0.995	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.005	0.995	0.000
Q55.6 Other congenital malformations of penis	0.005	0.995	0.000
Q55.5 Congenital absence and aplasia of penis	0.005	0.995	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.005	0.995	0.000
Q55.3 Atresia of vas deferens	0.005	0.995	0.000
Q55.1 Hypoplasia of testis and scrotum	0.005	0.995	0.000
Q55.0 Absence and aplasia of testis	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
E04 Other non-toxic goitre	0.000	0.995	0.005
Q38 Other congenital malformations of tongue, mouth and pharynx	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
E06.9 Thyroiditis, unspecified	0.000	0.995	0.005
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.995	0.005
E00 Congenital iodine-deficiency syndrome	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.995	0.005
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.005	0.995	0.000
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
Q50.3 Other congenital malformations of ovary	0.005	0.995	0.000
Q50.2 Congenital torsion of ovary	0.005	0.995	0.000
Q50.1 Developmental ovarian cyst	0.005	0.995	0.000
Q50.0 Congenital absence of ovary	0.005	0.995	0.000
D46 Myelodysplastic syndromes	0.000	0.995	0.005
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.995	0.005
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.005	0.995	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.995	0.000
E03 Other hypothyroidism	0.000	0.995	0.005
Q44.4 Choledochal cyst	0.004	0.995	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.004	0.995	0.000
Q44.2 Atresia of bile ducts	0.004	0.995	0.000
Q44.1 Other congenital malformations of gallbladder	0.004	0.995	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.004	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.004	0.995	0.000
M54.35 Sciatica (Thoracolumbar region)	0.004	0.995	0.000
M54.34 Sciatica-Thoracic	0.004	0.995	0.000
M54.33 Sciatica-Cervicothoracic	0.004	0.995	0.000
M54.32 Sciatica-Cervical	0.004	0.995	0.000
M54.31 Sciatica-Occipit-atl-axl	0.004	0.995	0.000
M54.30 Sciatica (Multiple sites in spine)	0.004	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.995	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.996	0.004
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
D48.1 Connective and other soft tissue	0.000	0.996	0.004
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
E03.8 Other specified hypothyroidism	0.000	0.996	0.004
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
H54.4 Blindness, one eye	0.000	0.996	0.004
D37.9 Digestive organ, unspecified	0.000	0.996	0.004
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.004	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.004	0.996	0.000
Z36 Antenatal screening	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
Q04 Other congenital malformations of brain	0.004	0.996	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.996	0.004
Q40.1 Congenital hiatus hernia	0.004	0.996	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.996	0.004
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
Q01 Encephalocele	0.004	0.996	0.000
Q00 Anencephaly and similar malformations	0.004	0.996	0.000
Q02 Microcephaly	0.004	0.996	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.996	0.004
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
D43.2 Brain, unspecified	0.000	0.996	0.004
D43.1 Brain, infratentorial	0.000	0.996	0.004
E04.8 Other specified non-toxic goitre	0.000	0.996	0.004
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q38.8 Other congenital malformations of pharynx	0.004	0.996	0.000
Q38.6 Other congenital malformations of mouth	0.004	0.996	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.004	0.996	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.004	0.996	0.000
Q38.3 Other congenital malformations of tongue	0.004	0.996	0.000
Q38.2 Macroglossia	0.004	0.996	0.000
Q38.1 Ankyloglossia	0.004	0.996	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.996	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.996	0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.996	0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.996	0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.996	0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.996	0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.996	0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.996	0.004
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.996	0.004
Q17 Other congenital malformations of ear	0.004	0.996	0.000
C18.4 Transverse colon	0.000	0.996	0.004
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.996	0.004
Q36 Cleft lip	0.003	0.996	0.000
Q35 Cleft palate	0.003	0.996	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.996	0.004
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.996	0.004
D46.4 Refractory anaemia, unspecified	0.000	0.996	0.004
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.996	0.004
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.996	0.004
Q24.0 Dextrocardia	0.004	0.996	0.000
E07 Other disorders of thyroid	0.000	0.996	0.004
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
E03.5 Myxoedema coma	0.000	0.996	0.003
E03.4 Atrophy of thyroid (acquired)	0.000	0.996	0.003
E03.3 Postinfectious hypothyroidism	0.000	0.996	0.003
E03.1 Congenital hypothyroidism without goitre	0.000	0.996	0.003
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.996	0.003
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.996	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.996	0.004
Q76.5 Cervical rib	0.003	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.996	0.000
Q65.6 Unstable hip	0.003	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.996	0.000
Q76.0 Spina bifida occulta	0.003	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.996	0.000
Q66.7 Pes cavus	0.003	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.996	0.000
Q24.2 Cor triatriatum	0.003	0.996	0.000
Q24.1 Levocardia	0.003	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.996	0.000
Q33 Congenital malformations of lung	0.003	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.996	0.000
Q31 Congenital malformations of larynx	0.003	0.996	0.000
Q30 Congenital malformations of nose	0.003	0.996	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.003	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.000	0.997	0.003
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
D43.0 Brain, supratentorial	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
D43.9 Central nervous system, unspecified	0.000	0.997	0.003
D43.7 Other parts of central nervous system	0.000	0.997	0.003
D43.4 Spinal cord	0.000	0.997	0.003
D43.3 Cranial nerves	0.000	0.997	0.003
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
A08.4 Viral intestinal infection, unspecified	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.997	0.003
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations