TreeWAS – Variant ID: rs2647012

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
D86 Sarcoidosis	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.000	1.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.999	0.001	0.000
D86.9 Sarcoidosis, unspecified	0.999	0.001	0.000
J33.9 Nasal polyp, unspecified	0.000	0.001	0.999
M05 Seropositive rheumatoid arthritis	0.000	0.002	0.998
M06.3 Rheumatoid nodule	0.000	0.002	0.998
M05-M14 Inflammatory polyarthropathies	0.000	0.003	0.997
N48 Other disorders of penis	0.000	0.003	0.997
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.003	0.997
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.003	0.997
L40.9 Psoriasis, unspecified	0.000	0.005	0.995
D68 Other coagulation defects	0.995	0.005	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.006	0.994
D69 Purpura and other haemorrhagic conditions	0.993	0.007	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.009	0.991
J33 Nasal polyp	0.000	0.014	0.986
K90 Intestinal malabsorption	0.984	0.016	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.016	0.984
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.018	0.982
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.981	0.019	0.000
J33.0 Polyp of nasal cavity	0.000	0.021	0.979
N48.0 Leukoplakia of penis	0.000	0.026	0.974
M06.34 Rheumatoid nodule (Hand)	0.000	0.027	0.973
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.028	0.972
D69.6 Thrombocytopenia, unspecified	0.971	0.029	0.000
N40-N51 Diseases of male genital organs	0.000	0.031	0.969
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.036	0.964
E05 Thyrotoxicosis [hyperthyroidism]	0.963	0.036	0.000
E05.9 Thyrotoxicosis, unspecified	0.959	0.041	0.000
K90.9 Intestinal malabsorption, unspecified	0.955	0.045	0.000
D86.0 Sarcoidosis of lung	0.954	0.046	0.000
D68.5 Primary Thrombophilia	0.953	0.047	0.000
D50-D53 Nutritional anaemias	0.952	0.048	0.000
N48.1 Balanoposthitis	0.000	0.054	0.946
N48.2 Other inflammatory disorders of penis	0.000	0.057	0.943
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.940	0.060	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.928	0.072	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.073	0.927
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.077	0.923
E78.0 Pure hypercholesterolaemia	0.000	0.079	0.921
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.084	0.916
D69.4 Other primary thrombocytopenia	0.916	0.084	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.084	0.916
D52 Folate deficiency anaemia	0.916	0.084	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.084	0.916
D68.8 Other specified coagulation defects	0.909	0.091	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.902	0.098	0.000
C82.0 Small cleaved cell, follicular	0.000	0.099	0.901
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.103	0.897
D52.9 Folate deficiency anaemia, unspecified	0.891	0.109	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.112	0.888
D69.3 Idiopathic thrombocytopenic purpura	0.886	0.114	0.000
C34 Malignant neoplasm of bronchus and lung	0.877	0.123	0.000
C34.9 Bronchus or lung, unspecified	0.877	0.123	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.126	0.874
N48.5 Ulcer of penis	0.000	0.131	0.869
C34.3 Lower lobe, bronchus or lung	0.865	0.135	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.861	0.139	0.000
N48.9 Disorder of penis, unspecified	0.000	0.140	0.860
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.146	0.854
M06.4 Inflammatory polyarthropathy	0.000	0.146	0.854
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.151	0.849
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.843	0.157	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.843	0.157	0.000
N48.8 Other specified disorders of penis	0.000	0.158	0.842
C82.3 Follicular lymphoma grade IIIa	0.000	0.166	0.834
L40 Psoriasis	0.000	0.168	0.832
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.169	0.831
D68.0 Von Willebrand's disease	0.829	0.171	0.000
C82.2 Large cell, follicular	0.000	0.177	0.823
D69.8 Other specified haemorrhagic conditions	0.822	0.178	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.184	0.816
J33.8 Other polyp of sinus	0.000	0.190	0.810
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.208	0.792
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.208	0.792
D86.1 Sarcoidosis of lymph nodes	0.785	0.214	0.000
D68.6 Other Thrombophilia	0.785	0.215	0.000
D51 Vitamin B12 deficiency anaemia	0.785	0.215	0.000
D86.3 Sarcoidosis of skin	0.785	0.215	0.000
C34.1 Upper lobe, bronchus or lung	0.783	0.217	0.000
K90.8 Other intestinal malabsorption	0.783	0.217	0.000
C34.2 Middle lobe, bronchus or lung	0.781	0.219	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.223	0.777
D68.9 Coagulation defect, unspecified	0.777	0.223	0.000
C34.0 Main bronchus	0.768	0.232	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.233	0.767
N48.4 Impotence of organic origin	0.000	0.233	0.767
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.233	0.767
L40.5 Arthropathic psoriasis	0.000	0.238	0.762
M45 Ankylosing spondylitis	0.000	0.240	0.760
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.240	0.760
M14 Arthropathies in other diseases classified elsewhere	0.000	0.241	0.759
C82.4 Follicular lymphoma grade IIIb	0.000	0.243	0.757
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.254	0.746
N44 Torsion of testis	0.000	0.257	0.742
D82 Immunodeficiency associated with other major defects	0.742	0.258	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.259	0.741
N49.2 Inflammatory disorders of scrotum	0.000	0.259	0.741
D67 Hereditary factor IX deficiency	0.739	0.261	0.000
D55-D59 Haemolytic anaemias	0.739	0.261	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.263	0.737
J33.1 Polypoid sinus degeneration	0.000	0.263	0.737
M05.2 Rheumatoid vasculitis	0.000	0.270	0.729
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.727	0.273	0.000
D68.4 Acquired coagulation factor deficiency	0.722	0.278	0.000
D89.1 Cryoglobulinaemia	0.721	0.279	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
D81 Combined immunodeficiencies	0.717	0.283	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.283	0.716
M05.8 Other seropositive rheumatoid arthritis	0.000	0.284	0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.284	0.716
M05.1 Rheumatoid lung disease	0.000	0.284	0.716
M05.0 Felty's syndrome	0.000	0.284	0.716
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.284	0.716
M06.38 Rheumatoid nodule (Other)	0.000	0.284	0.716
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.284	0.716
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.284	0.716
M06.33 Rheumatoid nodule (Forearm)	0.000	0.284	0.716
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.284	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.285	0.715
M08 Juvenile arthritis	0.000	0.285	0.715
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.287	0.713
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.287	0.713
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.287	0.713
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.287	0.713
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.287	0.713
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.289	0.711
D53 Other nutritional anaemias	0.709	0.291	0.000
D69.5 Secondary thrombocytopenia	0.708	0.292	0.000
M12 Other specific arthropathies	0.000	0.294	0.706
K90.3 Pancreatic steatorrhoea	0.706	0.294	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.706	0.294	0.000
K90.1 Tropical sprue	0.706	0.294	0.000
C34.8 Overlapping lesion of bronchus and lung	0.705	0.295	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.296	0.704
C82.5 Diffuse follicle centre lymphoma	0.000	0.296	0.704
D89.3 Immune reconstitution syndrome	0.704	0.296	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.703	0.297	0.000
E05.5 Thyroid crisis or storm	0.691	0.309	0.000
E05.4 Thyrotoxicosis factitia	0.691	0.309	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.691	0.309	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.691	0.309	0.000
N48.3 Priapism	0.000	0.310	0.690
M06.1 Adult-onset Still's disease	0.000	0.310	0.690
D83 Common variable immunodeficiency	0.688	0.312	0.000
D68.1 Hereditary factor XI deficiency	0.686	0.313	0.000
D84 Other immunodeficiencies	0.685	0.315	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.679	0.321	0.000
C21.1 Anal canal	0.000	0.324	0.676
C21.0 Anus, unspecified	0.000	0.326	0.674
C21 Malignant neoplasm of anus and anal canal	0.000	0.331	0.669
D86.8 Sarcoidosis of other and combined sites	0.665	0.335	0.000
D69.1 Qualitative platelet defects	0.665	0.335	0.000
M14.6 Neuropathic arthropathy	0.000	0.340	0.660
D69.2 Other nonthrombocytopenic purpura	0.659	0.341	0.000
D52.8 Other folate deficiency anaemias	0.657	0.343	0.000
D52.1 Drug-induced folate deficiency anaemia	0.657	0.343	0.000
D52.0 Dietary folate deficiency anaemia	0.657	0.343	0.000
D69.0 Allergic purpura	0.652	0.348	0.000
M11 Other crystal arthropathies	0.000	0.351	0.649
L40.8 Other psoriasis	0.000	0.358	0.642
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.642	0.358	0.000
M07.3 Other psoriatic arthropathies	0.000	0.359	0.641
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.359	0.641
G37 Other demyelinating diseases of central nervous system	0.637	0.363	0.000
D68.2 Hereditary deficiency of other clotting factors	0.634	0.366	0.000
D59 Acquired haemolytic anaemia	0.632	0.368	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.374	0.626
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.388	0.612
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.388	0.612
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.388	0.612
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.388	0.612
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.388	0.612
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.388	0.612
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.388	0.612
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.388	0.612
D80 Immunodeficiency with predominantly antibody defects	0.610	0.390	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.391	0.608
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.391	0.608
D60-D64 Aplastic and other anaemias	0.605	0.395	0.000
L40.1 Generalised pustular psoriasis	0.000	0.402	0.598
L40.4 Guttate psoriasis	0.000	0.404	0.596
L40.2 Acrodermatitis continua	0.000	0.404	0.596
L40.0 Psoriasis vulgaris	0.000	0.408	0.592
E05.8 Other thyrotoxicosis	0.583	0.417	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.417	0.583
N51.2 Balanitis in diseases classified elsewhere	0.000	0.429	0.571
L40.3 Pustulosis palmaris et plantaris	0.000	0.431	0.569
D51.8 Other vitamin B12 deficiency anaemias	0.568	0.432	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.563	0.437	0.000
D51.2 Transcobalamin II deficiency	0.563	0.437	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.563	0.437	0.000
D59.1 Other autoimmune haemolytic anaemias	0.562	0.438	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.438	0.562
M07.5 Arthropathy in ulcerative colitis	0.000	0.442	0.557
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.442	0.557
M07.2 Psoriatic spondylitis	0.000	0.442	0.557
M07.1 Arthritis mutilans	0.000	0.442	0.557
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.442	0.557
D82.1 Di George's syndrome	0.557	0.443	0.000
M14.2 Diabetic arthropathy	0.000	0.447	0.553
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.454	0.546
D84.1 Defects in the complement system	0.546	0.454	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.455	0.545
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.455	0.545
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.455	0.545
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.455	0.545
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.455	0.545
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.455	0.545
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.456	0.544
M14.4 Arthropathy in amyloidosis	0.000	0.456	0.544
M14.3 Lipoid dermatoarthritis	0.000	0.456	0.544
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.456	0.544
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.456	0.544
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.458	0.541
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.459	0.541
G37.9 Demyelinating disease of central nervous system, unspecified	0.538	0.462	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.463	0.537
D53.9 Nutritional anaemia, unspecified	0.535	0.464	0.000
D61 Other aplastic anaemias	0.533	0.467	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.532	0.468	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.532	0.468	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.532	0.468	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.532	0.468	0.000
D82.2 Immunodeficiency with short-limbed stature	0.532	0.468	0.000
D82.0 Wiskott-Aldrich syndrome	0.532	0.468	0.000
N42 Other disorders of prostate	0.000	0.468	0.532
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.468	0.531
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.468	0.531
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.468	0.531
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.468	0.531
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.468	0.531
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.468	0.531
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.468	0.531
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.468	0.531
D55 Anaemia due to enzyme disorders	0.530	0.470	0.000
N45 Orchitis and epididymitis	0.000	0.470	0.530
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.529	0.471	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.471	0.528
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.471	0.528
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.471	0.528
M12.3 Palindromic rheumatism	0.000	0.472	0.528
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.473	0.527
G37.8 Other specified demyelinating diseases of central nervous system	0.525	0.475	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.476	0.524
M05.28 Rheumatoid vasculitis (Other)	0.000	0.477	0.523
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.477	0.523
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.477	0.523
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.477	0.523
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.477	0.523
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.477	0.523
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.477	0.523
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.477	0.523
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.477	0.523
M07.6 Other enteropathic arthropathies	0.000	0.477	0.523
G36 Other acute disseminated demyelination	0.520	0.480	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
D81.9 Combined immunodeficiency, unspecified	0.514	0.486	0.000
D81.8 Other combined immunodeficiencies	0.514	0.486	0.000
D81.7 Major histocompatibility complex class II deficiency	0.514	0.486	0.000
D81.6 Major histocompatibility complex class I deficiency	0.514	0.486	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.514	0.486	0.000
D81.4 Nezelof's syndrome	0.514	0.486	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.514	0.486	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.514	0.486	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.514	0.486	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.487	0.513
M05.08 Felty's syndrome (Other)	0.000	0.487	0.513
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.487	0.513
M05.06 Felty's syndrome (Lower leg)	0.000	0.487	0.513
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.487	0.513
M05.04 Felty's syndrome (Hand)	0.000	0.487	0.513
M05.03 Felty's syndrome (Forearm)	0.000	0.487	0.513
M05.02 Felty's syndrome (Upper arm)	0.000	0.487	0.513
M05.01 Felty's syndrome (Shoulder region)	0.000	0.487	0.513
M05.00 Felty's syndrome (Multiple sites)	0.000	0.487	0.513
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.487	0.513
M05.18 Rheumatoid lung disease (Other)	0.000	0.487	0.513
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.487	0.513
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.487	0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.487	0.513
M05.14 Rheumatoid lung disease (Hand)	0.000	0.487	0.513
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.487	0.513
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.487	0.513
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.487	0.513
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.487	0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.487	0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.487	0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.487	0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.487	0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.487	0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.487	0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.487	0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.487	0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.487	0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.487	0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.487	0.513
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.487	0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.487	0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.487	0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.487	0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.487	0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.487	0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.487	0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.487	0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.487	0.513
M08.9 Juvenile arthritis, unspecified	0.000	0.487	0.513
M08.8 Other juvenile arthritis	0.000	0.487	0.513
M08.4 Pauciarticular juvenile arthritis	0.000	0.487	0.513
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.487	0.513
M08.2 Juvenile arthritis with systemic onset	0.000	0.487	0.513
M08.1 Juvenile ankylosing spondylitis	0.000	0.487	0.513
M08.0 Juvenile rheumatoid arthritis	0.000	0.487	0.513
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.487	0.513
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.487	0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.487	0.513
M09.0 Juvenile arthritis in psoriasis	0.000	0.487	0.513
D53.8 Other specified nutritional anaemias	0.508	0.491	0.000
D53.2 Scorbutic anaemia	0.508	0.491	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.508	0.491	0.000
D53.0 Protein deficiency anaemia	0.508	0.491	0.000
D57 Sickle-cell disorders	0.507	0.493	0.000
M12.5 Traumatic arthropathy	0.000	0.493	0.506
M12.4 Intermittent hydrarthrosis	0.000	0.493	0.506
M12.1 Kaschin-Beck disease	0.000	0.493	0.506
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.493	0.506
M12.2 Villonodular synovitis (pigmented)	0.000	0.495	0.505
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.500	0.500
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.498	0.502	0.000
D69.9 Haemorrhagic condition, unspecified	0.497	0.502	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.505	0.495
M06.18 Adult-onset Still's disease (Other)	0.000	0.505	0.495
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.505	0.495
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.505	0.495
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.505	0.495
M06.14 Adult-onset Still's disease (Hand)	0.000	0.505	0.495
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.505	0.495
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.505	0.495
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.505	0.495
D83.8 Other common variable immunodeficiencies	0.493	0.506	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.493	0.506	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.493	0.506	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.493	0.506	0.000
D66 Hereditary factor VIII deficiency	0.492	0.508	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.491	0.509	0.000
D50 Iron deficiency anaemia	0.488	0.512	0.000
D84.8 Other specified immunodeficiencies	0.487	0.513	0.000
D58 Other hereditary haemolytic anaemias	0.486	0.514	0.000
D61.9 Aplastic anaemia, unspecified	0.484	0.516	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.516	0.484
C21.2 Cloacogenic zone	0.000	0.520	0.480
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.526	0.474
D56 Thalassaemia	0.469	0.530	0.000
N40 Hyperplasia of prostate	0.000	0.531	0.469
M11.9 Crystal arthropathy, unspecified	0.000	0.531	0.469
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.532	0.467
M11.1 Familial chondrocalcinosis	0.000	0.534	0.465
M11.0 Hydroxyapatite deposition disease	0.000	0.534	0.465
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.465	0.535	0.000
D83.9 Common variable immunodeficiency, unspecified	0.465	0.535	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.540	0.460
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.540	0.460
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.540	0.460
G37.5 Concentric sclerosis [Balo]	0.457	0.543	0.000
G37.4 Subacute necrotising myelitis	0.457	0.543	0.000
G37.2 Central pontine myelinolysis	0.457	0.543	0.000
G37.1 Central demyelination of corpus callosum	0.457	0.543	0.000
G37.0 Diffuse sclerosis	0.457	0.543	0.000
D59.8 Other acquired haemolytic anaemias	0.453	0.547	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.453	0.547	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.453	0.547	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.453	0.547	0.000
D59.3 Haemolytic-uraemic syndrome	0.453	0.547	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.453	0.547	0.000
N42.2 Atrophy of prostate	0.000	0.548	0.452
M11.8 Other specified crystal arthropathies	0.000	0.550	0.450
D59.9 Acquired haemolytic anaemia, unspecified	0.446	0.553	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.444	0.555	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.557	0.443
M13 Other arthritis	0.000	0.558	0.442
D59.0 Drug-induced autoimmune haemolytic anaemia	0.440	0.560	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.437	0.563	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.437	0.563	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.437	0.563	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.437	0.563	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.437	0.563	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.425	0.575	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.579	0.420
N46 Male infertility	0.001	0.580	0.420
D61.0 Constitutional aplastic anaemia	0.418	0.582	0.000
E03 Other hypothyroidism	0.161	0.583	0.255
M11.2 Other chondrocalcinosis	0.000	0.585	0.415
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.588	0.412
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.588	0.411
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.592	0.408
E00-E07 Disorders of thyroid gland	0.392	0.595	0.013
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.598	0.402
D64 Other anaemias	0.402	0.598	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.600	0.400
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.600	0.400
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.600	0.400
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.600	0.400
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.600	0.400
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.600	0.400
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.600	0.400
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.600	0.400
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.600	0.400
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.600	0.400
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.600	0.400
M07.18 Arthritis mutilans (Other)	0.000	0.600	0.400
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.600	0.400
M07.16 Arthritis mutilans (Lower leg)	0.000	0.600	0.400
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.600	0.400
M07.14 Arthritis mutilans (Hand)	0.000	0.600	0.400
M07.13 Arthritis mutilans (Forearm)	0.000	0.600	0.400
M07.12 Arthritis mutilans (Upper arm)	0.000	0.600	0.400
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.600	0.400
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.600	0.400
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.600	0.400
M07.28 Psoriatic spondylitis (Other)	0.000	0.600	0.400
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.600	0.400
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.600	0.400
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.600	0.400
M07.24 Psoriatic spondylitis (Hand)	0.000	0.600	0.400
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.600	0.400
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.600	0.400
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.600	0.400
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.600	0.400
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.600	0.400
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.600	0.400
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.600	0.400
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.600	0.400
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.600	0.400
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.600	0.400
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.600	0.400
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.600	0.400
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.600	0.400
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.600	0.400
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.600	0.400
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.600	0.400
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.600	0.400
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.600	0.400
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.600	0.400
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.600	0.400
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.600	0.400
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.600	0.400
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.600	0.400
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.600	0.400
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.602	0.398
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.397	0.603	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.396	0.603	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.393	0.607	0.000
L40-L45 Papulosquamous disorders	0.001	0.609	0.390
G36.0 Neuromyelitis optica [Devic]	0.389	0.611	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.384	0.615	0.000
D61.8 Other specified aplastic anaemias	0.382	0.618	0.000
D61.3 Idiopathic aplastic anaemia	0.382	0.618	0.000
D61.2 Aplastic anaemia due to other external agents	0.382	0.618	0.000
N42.3 Dysplasia of prostate	0.000	0.618	0.381
D55.9 Anaemia due to enzyme disorder, unspecified	0.380	0.620	0.000
D55.8 Other anaemias due to enzyme disorders	0.380	0.620	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.380	0.620	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.380	0.620	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.380	0.620	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.380	0.620	0.000
M12.38 Palindromic rheumatism (Other)	0.000	0.621	0.379
M12.37 Palindromic rheumatism (Ankle and foot)	0.000	0.621	0.379
M12.36 Palindromic rheumatism (Lower leg)	0.000	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations