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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2647050
log Bayes Factor = 146.729
Chromosome 6   position 32,669,767  (GRCh37) Explore rs2647050 on Ensembl!
Variant rs2647050 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
N48 Other disorders of penis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.000 1.000
N48.6 Balanitis xerotica obliterans
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
E10.2 With renal complications
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
N48.1 Balanoposthitis
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.009 0.991
N40-N51 Diseases of male genital organs
0.987 0.013 0.000
N48.0 Leukoplakia of penis
0.973 0.027 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.035 0.965
M35.3 Polymyalgia rheumatica
0.000 0.037 0.963
M35 Other systemic involvement of connective tissue
0.000 0.038 0.962
L40 Psoriasis
0.955 0.045 0.000
L90.0 Lichen sclerosus et atrophicus
0.947 0.053 0.000
E50-E64 Other nutritional deficiencies
0.000 0.065 0.935
N48.8 Other specified disorders of penis
0.921 0.079 0.000
D07.1 Vulva
0.920 0.080 0.000
E55 Vitamin D deficiency
0.000 0.092 0.908
L40.0 Psoriasis vulgaris
0.905 0.095 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.901 0.099 0.000
N48.2 Other inflammatory disorders of penis
0.892 0.108 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.111 0.889
E10.0 With coma
0.000 0.115 0.885
D00-D09 In situ neoplasms
0.883 0.117 0.000
E06 Thyroiditis
0.000 0.120 0.880
L90 Atrophic disorders of skin
0.877 0.123 0.000
D06 Carcinoma in situ of cervix uteri
0.866 0.134 0.000
L90.5 Scar conditions and fibrosis of skin
0.863 0.137 0.000
N48.5 Ulcer of penis
0.853 0.147 0.000
D06.9 Cervix, unspecified
0.846 0.154 0.000
N44 Torsion of testis
0.842 0.158 0.000
C21.1 Anal canal
0.834 0.166 0.000
C21 Malignant neoplasm of anus and anal canal
0.827 0.173 0.000
C21.0 Anus, unspecified
0.827 0.173 0.000
D07.4 Penis
0.823 0.177 0.000
N48.9 Disorder of penis, unspecified
0.821 0.179 0.000
E03 Other hypothyroidism
0.648 0.191 0.161
E14.6 With other specified complications
0.000 0.195 0.805
E10.8 With unspecified complications
0.000 0.198 0.802
E40-E46 Malnutrition
0.000 0.200 0.800
M35.1 Other overlap syndromes
0.000 0.214 0.786
D04 Carcinoma in situ of skin
0.786 0.214 0.000
E14.8 With unspecified complications
0.000 0.216 0.784
L40.8 Other psoriasis
0.783 0.217 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.222 0.778
N45 Orchitis and epididymitis
0.777 0.223 0.000
E07 Other disorders of thyroid
0.000 0.225 0.775
L40.4 Guttate psoriasis
0.768 0.232 0.000
E14.5 With peripheral circulatory complications
0.000 0.234 0.766
N42 Other disorders of prostate
0.760 0.240 0.000
E10.6 With other specified complications
0.000 0.247 0.753
M35.2 Behcet's disease
0.000 0.248 0.752
D09 Carcinoma in situ of other and unspecified sites
0.751 0.249 0.000
N48.4 Impotence of organic origin
0.742 0.258 0.000
E06.9 Thyroiditis, unspecified
0.000 0.260 0.740
E51 Thiamine deficiency
0.000 0.261 0.739
D01 Carcinoma in situ of other and unspecified digestive organs
0.736 0.264 0.000
E06.3 Autoimmune thyroiditis
0.000 0.265 0.735
L40.1 Generalised pustular psoriasis
0.734 0.266 0.000
N48.3 Priapism
0.733 0.266 0.000
D04.7 Skin of lower limb, including hip
0.732 0.268 0.000
E14.2 Withrenal complications
0.000 0.273 0.727
E14.9 Without complications
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
D03 Melanoma in situ
0.717 0.283 0.000
E14.7 With multiple complications
0.000 0.284 0.715
E14.0 With coma
0.000 0.284 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.289 0.711
D04.9 Skin, unspecified
0.698 0.302 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.697 0.303 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.696 0.304 0.000
L40.5 Arthropathic psoriasis
0.691 0.309 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.310 0.689
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.310 0.689
M35.5 Multifocal fibrosclerosis
0.000 0.310 0.689
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.310 0.689
L40.2 Acrodermatitis continua
0.684 0.315 0.000
D06.1 Exocervix
0.684 0.316 0.000
E14.1 With ketoacidosis
0.000 0.321 0.678
L40.3 Pustulosis palmaris et plantaris
0.678 0.322 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.330 0.670
E63 Other nutritional deficiencies
0.000 0.330 0.670
E50 Vitamin A deficiency
0.000 0.330 0.670
E60 Dietary zinc deficiency
0.000 0.330 0.670
E59 Dietary selenium deficiency
0.000 0.330 0.670
E54 Ascorbic acid deficiency
0.000 0.330 0.670
E52 Niacin deficiency [pellagra]
0.000 0.330 0.670
D06.0 Endocervix
0.666 0.334 0.000
D09.1 Other and unspecified urinary organs
0.663 0.337 0.000
E07.8 Other specified disorders of thyroid
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.341 0.659
E46 Unspecified protein-energy malnutrition
0.000 0.344 0.656
D02 Carcinoma in situ of middle ear and respiratory system
0.653 0.347 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.652 0.348 0.000
E55.0 Rickets, active
0.000 0.349 0.651
D07.6 Other and unspecified male genital organs
0.646 0.354 0.000
D07.3 Other and unspecified female genital organs
0.646 0.354 0.000
D07.0 Endometrium
0.646 0.354 0.000
D04.3 Skin of other and unspecified parts of face
0.645 0.355 0.000
D01.3 Anus and anal canal
0.645 0.355 0.000
M35.7 Hypermobility syndrome
0.000 0.359 0.641
L90.8 Other atrophic disorders of skin
0.635 0.365 0.000
E06.4 Drug-induced thyroiditis
0.000 0.369 0.631
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.369 0.631
E06.1 Subacute thyroiditis
0.000 0.369 0.631
E06.0 Acute thyroiditis
0.000 0.369 0.631
E53 Deficiency of other B group vitamins
0.000 0.370 0.630
L90.9 Atrophic disorder of skin, unspecified
0.629 0.371 0.000
L90.6 Striae atrophicae
0.629 0.371 0.000
L90.4 Acrodermatitis chronica atrophicans
0.629 0.371 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.629 0.371 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.629 0.371 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.629 0.371 0.000
D07.2 Vagina
0.627 0.373 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.625 0.375 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.621 0.379 0.000
D06.7 Other parts of cervix
0.621 0.379 0.000
E06.5 Other chronic thyroiditis
0.000 0.383 0.617
D09.7 Carcinoma in situ of other specified sites
0.617 0.383 0.000
E14.4 With neurological complications
0.000 0.385 0.615
D04.4 Skin of scalp and neck
0.612 0.388 0.000
E58 Dietary calcium deficiency
0.000 0.388 0.612
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.389 0.611
M35.8 Other specified systemic involvement of connective tissue
0.000 0.392 0.608
E03.0 Congenital hypothyroidism with diffuse goitre
0.499 0.399 0.102
E61 Deficiency of other nutrient elements
0.000 0.399 0.601
E51.2 Wernicke's encephalopathy
0.000 0.402 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.508 0.403 0.089
N42.8 Other specified disorders of prostate
0.596 0.404 0.000
N42.3 Dysplasia of prostate
0.595 0.405 0.000
C21.2 Cloacogenic zone
0.593 0.407 0.000
N42.1 Congestion and haemorrhage of prostate
0.592 0.408 0.000
E56 Other vitamin deficiencies
0.000 0.410 0.590
N42.9 Disorder of prostate, unspecified
0.590 0.410 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.589 0.411 0.000
E03.5 Myxoedema coma
0.464 0.420 0.116
E03.4 Atrophy of thyroid (acquired)
0.464 0.420 0.116
E03.3 Postinfectious hypothyroidism
0.464 0.420 0.116
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.426 0.573
E45 Retarded development following protein-energy malnutrition
0.000 0.426 0.573
E43 Unspecified severe protein-energy malnutrition
0.000 0.426 0.573
E42 Marasmic kwashiorkor
0.000 0.426 0.573
E41 Nutritional marasmus
0.000 0.426 0.573
E40 Kwashiorkor
0.000 0.426 0.573
D03.5 Melanoma in situ of trunk
0.570 0.430 0.000
D03.8 Melanoma in situ of other sites
0.568 0.432 0.000
E03.1 Congenital hypothyroidism without goitre
0.455 0.432 0.113
D04.8 Skin of other sites
0.563 0.436 0.000
D04.0 Skin of lip
0.563 0.436 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.560 0.440 0.000
E07.1 Dyshormogenetic goitre
0.000 0.444 0.555
E07.0 Hypersecretion of calcitonin
0.000 0.444 0.555
N30.2 Other chronic cystitis
0.554 0.446 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.449 0.551
D04.1 Skin of eyelid, including canthus
0.541 0.459 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.539 0.461 0.000
N42.2 Atrophy of prostate
0.539 0.461 0.000
D09.9 Carcinoma in situ, unspecified
0.539 0.461 0.000
D09.3 Thyroid and other endocrine glands
0.539 0.461 0.000
D09.2 Eye
0.539 0.461 0.000
E03.8 Other specified hypothyroidism
0.437 0.466 0.097
G37 Other demyelinating diseases of central nervous system
0.000 0.468 0.532
E51.9 Thiamine deficiency, unspecified
0.000 0.470 0.530
E51.8 Other manifestations of thiamine deficiency
0.000 0.470 0.530
E51.1 Beriberi
0.000 0.470 0.530
D01.9 Digestive organ, unspecified
0.528 0.472 0.000
D01.7 Other specified digestive organs
0.528 0.472 0.000
D01.5 Liver, gallbladder and bile ducts
0.528 0.472 0.000
D01.4 Other and unspecified parts of intestine
0.528 0.472 0.000
D01.2 Rectum
0.528 0.472 0.000
D01.1 Rectosigmoid junction
0.528 0.472 0.000
N30 Cystitis
0.528 0.472 0.000
E04 Other non-toxic goitre
0.000 0.474 0.526
E16.1 Other hypoglycaemia
0.000 0.484 0.515
E27 Other disorders of adrenal gland
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
D03.9 Melanoma in situ, unspecified
0.514 0.486 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.514 0.486 0.000
D03.0 Melanoma in situ of lip
0.514 0.486 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.490 0.510
E53.9 Vitamin B deficiency, unspecified
0.000 0.493 0.507
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.497 0.503
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.500 0.500 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.500 0.500 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.500 0.500 0.000
N30.0 Acute cystitis
0.498 0.502 0.000
D01.0 Colon
0.497 0.503 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.505 0.494
N30.1 Interstitial cystitis (chronic)
0.490 0.510 0.000
N51.2 Balanitis in diseases classified elsewhere
0.489 0.511 0.000
E34 Other endocrine disorders
0.000 0.515 0.485
E50.9 Vitamin A deficiency, unspecified
0.000 0.519 0.481
E50.8 Other manifestations of vitamin A deficiency
0.000 0.519 0.481
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.519 0.481
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.519 0.481
E50.5 Vitamin A deficiency with night blindness
0.000 0.519 0.481
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.519 0.481
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.519 0.481
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.519 0.481
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.519 0.481
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.519 0.481
E63.9 Nutritional deficiency, unspecified
0.000 0.519 0.481
E63.8 Other specified nutritional deficiencies
0.000 0.519 0.481
E63.1 Imbalance of constituents of food intake
0.000 0.519 0.481
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.519 0.481
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.519 0.481
E64.8 Sequelae of other nutritional deficiencies
0.000 0.519 0.481
E64.3 Sequelae of rickets
0.000 0.519 0.481
E64.2 Sequelae of vitamin C deficiency
0.000 0.519 0.481
E64.1 Sequelae of vitamin A deficiency
0.000 0.519 0.481
E64.0 Sequelae of protein-energy malnutrition
0.000 0.519 0.481
D02.0 Larynx
0.480 0.520 0.000
D02.2 Bronchus and lung
0.476 0.524 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.531 0.469
D02.4 Respiratory system, unspecified
0.468 0.532 0.000
D02.3 Other parts of respiratory system
0.468 0.532 0.000
D02.1 Trachea
0.468 0.532 0.000
L40-L45 Papulosquamous disorders
0.467 0.533 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.536 0.464
N46 Male infertility
0.462 0.537 0.001
N90 Other noninflammatory disorders of vulva and perineum
0.462 0.538 0.000
E61.2 Magnesium deficiency
0.000 0.541 0.459
E13 Other specified diabetes mellitus
0.001 0.543 0.456
N90.7 Vulvar cyst
0.456 0.544 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.544 0.456
D03.7 Melanoma in situ of lower limb, including hip
0.456 0.544 0.000
D00.0 Lip, oral cavity and pharynx
0.454 0.546 0.000
N90.4 Leukoplakia of vulva
0.454 0.546 0.000
E53.1 Pyridoxine deficiency
0.000 0.548 0.451
E53.0 Riboflavin deficiency
0.000 0.548 0.451
N30.3 Trigonitis
0.450 0.550 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.552 0.447
D00.2 Stomach
0.445 0.555 0.000
K90 Intestinal malabsorption
0.000 0.555 0.445
N30.4 Irradiation cystitis
0.439 0.561 0.000
G36 Other acute disseminated demyelination
0.000 0.562 0.438
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.566 0.434
E61.9 Deficiency of nutrient element, unspecified
0.000 0.569 0.431
E61.8 Deficiency of other specified nutrient elements
0.000 0.569 0.431
E61.7 Deficiency of multiple nutrient elements
0.000 0.569 0.431
E61.6 Vanadium deficiency
0.000 0.569 0.431
E61.5 Molybdenum deficiency
0.000 0.569 0.431
E61.4 Chromium deficiency
0.000 0.569 0.431
E61.3 Manganese deficiency
0.000 0.569 0.431
E61.0 Copper deficiency
0.000 0.569 0.431
E27.8 Other specified disorders of adrenal gland
0.000 0.572 0.428
D04.5 Skin of trunk
0.428 0.572 0.000
N90.3 Dysplasia of vulva, unspecified
0.428 0.572 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.577 0.423
E56.8 Deficiency of other vitamins
0.000 0.577 0.423
E56.0 Deficiency of vitamin E
0.000 0.577 0.423
D00.1 Oesophagus
0.423 0.577 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.422 0.578 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.580 0.419
E34.0 Carcinoid syndrome
0.000 0.587 0.413
E44.1 Mild protein-energy malnutrition
0.000 0.589 0.411
E44.0 Moderate protein-energy malnutrition
0.000 0.589 0.411
N90.1 Moderate vulvar dysplasia
0.409 0.591 0.000
E28 Ovarian dysfunction
0.000 0.594 0.406
N41 Inflammatory diseases of prostate
0.401 0.599 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.398 0.602 0.000
N43 Hydrocele and spermatocele
0.396 0.604 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.605 0.395
E32 Diseases of thymus
0.000 0.605 0.395
E31 Polyglandular dysfunction
0.000 0.605 0.395
E30 Disorders of puberty, not elsewhere classified
0.000 0.605 0.395
E26 Hyperaldosteronism
0.000 0.606 0.394
D09.0 Bladder
0.391 0.609 0.000
L42 Pityriasis rosea
0.390 0.610 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.386 0.613 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.386 0.613 0.000
N90.0 Mild vulvar dysplasia
0.385 0.615 0.000
E29 Testicular dysfunction
0.000 0.615 0.385
D04.2 Skin of ear and external auricular canal
0.383 0.617 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.618 0.382
G37.4 Subacute necrotising myelitis
0.000 0.618 0.382
G37.2 Central pontine myelinolysis
0.000 0.618 0.382
G37.1 Central demyelination of corpus callosum
0.000 0.618 0.382
G37.0 Diffuse sclerosis
0.000 0.618 0.382
N30.8 Other cystitis
0.381 0.619 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.621 0.379
E04.8 Other specified non-toxic goitre
0.000 0.623 0.377
L44 Other papulosquamous disorders
0.376 0.624 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.629 0.371
E27.5 Adrenomedullary hyperfunction
0.000 0.631 0.369
E27.0 Other adrenocortical overactivity
0.000 0.631 0.369
E22 Hyperfunction of pituitary gland
0.000 0.632 0.368
E34.8 Other specified endocrine disorders
0.000 0.634 0.366
D03.4 Melanoma in situ of scalp and neck
0.365 0.635 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.637 0.363
E20 Hypoparathyroidism
0.000 0.643 0.356
E34.5 Androgen resistance syndrome
0.000 0.652 0.347
E34.4 Constitutional tall stature
0.000 0.652 0.347
E34.3 Short stature, not elsewhere classified
0.000 0.652 0.347
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.652 0.347
E34.1 Other hypersecretion of intestinal hormones
0.000 0.652 0.347
E56.1 Deficiency of vitamin K
0.001 0.656 0.343
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.343 0.657 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.661 0.339
L41 Parapsoriasis
0.335 0.665 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.335 0.665 0.000
E25 Adrenogenital disorders
0.000 0.666 0.333
N49.8 Inflammatory disorders of other specified male genital organs
0.333 0.667 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.331 0.669 0.000
E13.8 With unspecified complications
0.001 0.672 0.327
E13.7 With multiple complications
0.001 0.672 0.327
E13.6 With other specified complications
0.001 0.672 0.327
E13.5 With peripheral circulatory complications
0.001 0.672 0.327
E13.4 With neurological complications
0.001 0.672 0.327
E13.2 With renal complications
0.001 0.672 0.327
E13.1 With ketoacidosis
0.001 0.672 0.327
E13.0 With coma
0.001 0.672 0.327
D04.6 Skin of upper limb, including shoulder
0.327 0.672 0.000
J45 Asthma
0.326 0.674 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.679 0.321
K90.9 Intestinal malabsorption, unspecified
0.000 0.679 0.321
K90.3 Pancreatic steatorrhoea
0.000 0.681 0.319
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.681 0.319
K90.1 Tropical sprue
0.000 0.681 0.319
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.683 0.317
N42.0 Calculus of prostate
0.316 0.684 0.000
K90.8 Other intestinal malabsorption
0.000 0.685 0.315
G36.9 Acute disseminated demyelination, unspecified
0.000 0.685 0.314
G36.8 Other specified acute disseminated demyelination
0.000 0.685 0.314
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.685 0.314
G36.0 Neuromyelitis optica [Devic]
0.000 0.685 0.314
E61.1 Iron deficiency
0.000 0.687 0.313
E53.8 Deficiency of other specified B group vitamins
0.000 0.688 0.312
E13.3 With ophthalmic complications
0.001 0.688 0.311
L44.0 Pityriasis rubra pilaris
0.310 0.690 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.694 0.306
N43.2 Other hydrocele
0.306 0.694 0.000
E22.1 Hyperprolactinaemia
0.000 0.695 0.305
E67 Other hyperalimentation
0.000 0.699 0.301
E68 Sequelae of hyperalimentation
0.000 0.699 0.301
N41.0 Acute prostatitis
0.300 0.700 0.000
N43.1 Infected hydrocele
0.297 0.703 0.000
D07.5 Prostate
0.295 0.705 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.705 0.294
E28.9 Ovarian dysfunction, unspecified
0.000 0.709 0.291
E28.8 Other ovarian dysfunction
0.000 0.709 0.291
E28.1 Androgen excess
0.000 0.709 0.291
E28.0 Oestrogen excess
0.000 0.709 0.291
N41.3 Prostatocystitis
0.287 0.713 0.000
N41.2 Abscess of prostate
0.287 0.713 0.000
E28.3 Primary ovarian failure
0.000 0.713 0.287
E29.1 Testicular hypofunction
0.000 0.716 0.284
N43.0 Encysted hydrocele
0.284 0.716 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.716 0.283
E30.9 Disorder of puberty, unspecified
0.000 0.717 0.283
E30.8 Other disorders of puberty
0.000 0.717 0.283
E30.1 Precocious puberty
0.000 0.717 0.283
E30.0 Delayed puberty
0.000 0.717 0.283
E31.9 Polyglandular dysfunction, unspecified
0.000 0.717 0.283
E31.8 Other polyglandular dysfunction
0.000 0.717 0.283
E31.1 Polyglandular hyperfunction
0.000 0.717 0.283
E31.0 Autoimmune polyglandular failure
0.000 0.717 0.283
E32.9 Disease of thymus, unspecified
0.000 0.717 0.283
E32.8 Other diseases of thymus
0.000 0.717 0.283
E32.1 Abscess of thymus
0.000 0.717 0.283
E32.0 Persistent hyperplasia of thymus
0.000 0.717 0.283
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.717 0.283
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.717 0.283
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.717 0.283
N49.2 Inflammatory disorders of scrotum
0.282 0.718 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.718 0.282
E26.8 Other hyperaldosteronism
0.000 0.718 0.282
E26.1 Secondary hyperaldosteronism
0.000 0.718 0.282
N90.6 Hypertrophy of vulva
0.281 0.719 0.000
E26.0 Primary hyperaldosteronism
0.000 0.719 0.281
E11 Non-insulin-dependent diabetes mellitus
0.000 0.723 0.277
E65 Localised adiposity
0.000 0.723 0.277
E29.8 Other testicular dysfunction
0.000 0.724 0.276
E29.0 Testicular hyperfunction
0.000 0.724 0.276
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.728 0.272
L44.9 Papulosquamous disorder, unspecified
0.270 0.730 0.000
L44.8 Other specified papulosquamous disorders
0.270 0.730 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.270 0.730 0.000
L44.3 Lichen ruber moniliformis
0.270 0.730 0.000
L44.2 Lichen striatus
0.270 0.730 0.000
L44.1 Lichen nitidus
0.270 0.730 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.733 0.267
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.736 0.264
E22.8 Other hyperfunction of pituitary gland
0.000 0.736 0.264
N41.8 Other inflammatory diseases of prostate
0.264 0.736 0.000
E27.2 Addisonian crisis
0.000 0.736 0.263
E29.9 Testicular dysfunction, unspecified
0.000 0.743 0.256
E20.8 Other hypoparathyroidism
0.000 0.744 0.256
E20.1 Pseudohypoparathyroidism
0.000 0.744 0.256
E20.0 Idiopathic hypoparathyroidism
0.000 0.744 0.256
E22.0 Acromegaly and pituitary gigantism
0.000 0.747 0.253
E04.9 Non-toxic goitre, unspecified
0.000 0.755 0.245
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.757 0.243
E23.1 Drug-induced hypopituitarism
0.000 0.757 0.243
E11.3 With ophthalmic complications
0.000 0.758 0.242
N41.1 Chronic prostatitis
0.242 0.758 0.000
L41.9 Parapsoriasis, unspecified
0.240 0.759 0.000
L41.8 Other parapsoriasis
0.240 0.759 0.000
L41.5 Retiform parapsoriasis
0.240 0.759 0.000
L41.4 Large plaque parapsoriasis
0.240 0.759 0.000
L41.3 Small plaque parapsoriasis
0.240 0.759 0.000
L41.2 Lymphomatoid papulosis
0.240 0.759 0.000
L41.1 Pityriasis lichenoides chronica
0.240 0.759 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.240 0.759 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.761 0.239
E25.8 Other adrenogenital disorders
0.000 0.761 0.239
J45.8 Mixed asthma
0.237 0.763 0.000
E23.6 Other disorders of pituitary gland
0.000 0.764 0.236
N90.5 Atrophy of vulva
0.233 0.767 0.000
J45.1 Nonallergic asthma
0.231 0.769 0.000
L43 Lichen planus
0.222 0.778 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.219 0.780 0.000
E23.0 Hypopituitarism
0.000 0.781 0.219
E20.9 Hypoparathyroidism, unspecified
0.000 0.783 0.217
E67.8 Other specified hyperalimentation
0.000 0.784 0.216
E67.3 Hypervitaminosis D
0.000 0.784 0.216
E67.2 Megavitamin-B6 syndrome
0.000 0.784 0.216
E67.1 Hypercarotenaemia
0.000 0.784 0.216
E67.0 Hypervitaminosis A
0.000 0.784 0.216
D05 Carcinoma in situ of breast
0.211 0.789 0.000
E11.8 With unspecified complications
0.000 0.794 0.206
E11.0 With coma
0.000 0.796 0.204
E11.5 With peripheral circulatory complications
0.000 0.799 0.201
E11.7 With multiple complications
0.000 0.801 0.199
N43.4 Spermatocele
0.192 0.807 0.001
E23.2 Diabetes insipidus
0.000 0.811 0.189
J45.0 Predominantly allergic asthma
0.187 0.813 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.822 0.178
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.827 0.173
N30.9 Cystitis, unspecified
0.172 0.828 0.000
E11.1 With ketoacidosis
0.000 0.831 0.169
D05.7 Other carcinoma in situ of breast
0.166 0.834 0.000
L43.8 Other lichen planus
0.164 0.836 0.000
E11.6 With other specified complications
0.000 0.837 0.163
L43.3 Subacute (active) lichen planus
0.159 0.840 0.000
L43.2 Lichenoid drug reaction
0.159 0.840 0.000
L43.1 Bullous lichen planus
0.159 0.840 0.000
L43.0 Hypertrophic lichen planus
0.159 0.840 0.000
E11.4 With neurological complications
0.000 0.846 0.154
E11.2 With renal complications
0.000 0.846 0.154
E70-E90 Metabolic disorders
0.000 0.850 0.150
E83.1 Disorders of iron metabolism
0.000 0.856 0.144
E24 Cushing's syndrome
0.004 0.859 0.137
E83 Disorders of mineral metabolism
0.000 0.859 0.141
N50 Other disorders of male genital organs
0.138 0.862 0.000
D05.0 Lobular carcinoma in situ
0.138 0.862 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.870 0.130
E87.7 Fluid overload
0.000 0.872 0.128
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.873 0.127
N41.9 Inflammatory disease of prostate, unspecified
0.121 0.879 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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