TreeWAS – Variant ID: rs2648708

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.1 Hallux valgus (acquired)	0.696	0.304	0.000
M20 Acquired deformities of fingers and toes	0.386	0.614	0.000
M20.5 Other deformities of toe(s) (acquired)	0.364	0.636	0.000
M20.4 Other hammer toe(s) (acquired)	0.296	0.704	0.000
M20.0 Deformity of finger(s)	0.283	0.717	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.255	0.744	0.000
M20.2 Hallux rigidus	0.230	0.770	0.000
M20.3 Other deformity of hallux (acquired)	0.159	0.841	0.000
I95.9 Hypotension, unspecified	0.000	0.987	0.013
M20-M25 Other joint disorders	0.008	0.992	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.992	0.008
M34 Systemic sclerosis	0.008	0.992	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.993	0.007
D73.0 Hyposplenism	0.007	0.993	0.000
M84.0 Malunion of fracture	0.000	0.993	0.007
D22.4 Melanocytic naevi of scalp and neck	0.007	0.993	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.993	0.007
M34.9 Systemic sclerosis, unspecified	0.007	0.993	0.000
M22 Disorders of patella	0.007	0.993	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.993	0.000
I95 Hypotension	0.000	0.993	0.007
M34.1 CR(E)ST syndrome	0.006	0.993	0.000
M30 Polyarteritis nodosa and related conditions	0.006	0.994	0.000
M32 Systemic lupus erythematosus	0.006	0.994	0.000
M34.8 Other forms of systemic sclerosis	0.006	0.994	0.000
M21 Other acquired deformities of limbs	0.006	0.994	0.000
J22 Unspecified acute lower respiratory infection	0.000	0.994	0.006
M84.04 Malunion of fracture (Hand)	0.000	0.994	0.006
M34.0 Progressive systemic sclerosis	0.006	0.994	0.000
M33 Dermatopolymyositis	0.006	0.994	0.000
M23.8 Other internal derangements of knee	0.006	0.994	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.006	0.994	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.006	0.994	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.994	0.006
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.006	0.994	0.000
M22.0 Recurrent dislocation of patella	0.006	0.994	0.000
M21.0 Valgus deformity, not elsewhere classified	0.006	0.994	0.000
M22.4 Chondromalacia patellae	0.006	0.994	0.000
I95.0 Idiopathic hypotension	0.000	0.995	0.005
M84.02 Malunion of fracture (Upper arm)	0.000	0.995	0.005
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.995	0.005
I95.2 Hypotension due to drugs	0.000	0.995	0.005
M21.3 Wrist or foot drop (acquired)	0.005	0.995	0.000
M84.09 Malunion of fracture (Site unspecified)	0.000	0.995	0.005
M84.00 Malunion of fracture (Multiple sites)	0.000	0.995	0.005
C90.0 Multiple myeloma	0.000	0.995	0.005
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
M23 Internal derangement of knee	0.005	0.995	0.000
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.000	0.995	0.005
O16 Unspecified maternal hypertension	0.005	0.995	0.000
M22.3 Other derangements of patella	0.005	0.995	0.000
M22.1 Recurrent subluxation of patella	0.005	0.995	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.005	0.995	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.995	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.995	0.005
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.005	0.995	0.000
M30.2 Juvenile polyarteritis	0.005	0.995	0.000
M21.9 Acquired deformity of limb, unspecified	0.005	0.995	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.005	0.995	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.005	0.995	0.000
M21.4 Flat foot [pes planus] (acquired)	0.005	0.995	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.995	0.005
M21.6 Other acquired deformities of ankle and foot	0.005	0.995	0.000
M32.8 Other forms of systemic lupus erythematosus	0.005	0.995	0.000
K37 Unspecified appendicitis	0.000	0.995	0.005
M21.7 Unequal limb length (acquired)	0.005	0.995	0.000
M22.2 Patellofemoral disorders	0.005	0.995	0.000
I95.8 Other hypotension	0.000	0.995	0.005
M84.06 Malunion of fracture (Lower leg)	0.000	0.995	0.004
M21.8 Other specified acquired deformities of limbs	0.004	0.995	0.000
Z99.1 Dependence on respirator	0.000	0.995	0.005
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M33.9 Dermatopolymyositis, unspecified	0.004	0.995	0.000
M33.0 Juvenile dermatomyositis	0.004	0.995	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.995	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.004	0.995	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.004	0.995	0.000
M33.2 Polymyositis	0.004	0.995	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.004	0.995	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.995	0.000
M23.4 Loose body in knee	0.005	0.995	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.004	0.995	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.995	0.005
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.004	0.995	0.000
M36.3 Arthropathy in other blood disorders	0.004	0.995	0.000
M36.2 Haemophilic arthropathy	0.004	0.995	0.000
M36.1 Arthropathy in neoplastic disease	0.004	0.995	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.004	0.995	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.996	0.004
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.004	0.996	0.000
M21.1 Varus deformity, not elsewhere classified	0.004	0.996	0.000
M33.1 Other dermatomyositis	0.004	0.996	0.000
M47.9 Spondylosis, unspecified	0.000	0.996	0.004
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.004	0.996	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.004	0.996	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.004	0.996	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M23.1 Discoid meniscus (congenital)	0.004	0.996	0.000
M31 Other necrotising vasculopathies	0.004	0.996	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.004	0.996	0.000
M30.0 Polyarteritis nodosa	0.004	0.996	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.996	0.004
M21.33 Wrist or foot drop (acquired) (Forearm)	0.004	0.996	0.000
K09.2 Other cysts of jaw	0.000	0.996	0.004
F11.2 Dependence syndrome	0.000	0.996	0.004
M23.0 Cystic meniscus	0.004	0.996	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.004	0.996	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.004	0.996	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.004	0.996	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.004	0.996	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.004	0.996	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.004	0.996	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.004	0.996	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.004	0.996	0.000
F17.2 Dependence syndrome	0.000	0.996	0.004
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.004	0.996	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.004	0.996	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.004	0.996	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.004	0.996	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.004	0.996	0.000
M22.8 Other disorders of patella	0.004	0.996	0.000
M23.46 Loose body in knee-O/unsp lat men	0.004	0.996	0.000
M23.40 Loose body in knee-Mult sites	0.004	0.996	0.000
M23.49 Loose body in knee-Unspec lig/men	0.004	0.996	0.000
M23.9 Internal derangement of knee, unspecified	0.004	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.004	0.996	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.004	0.996	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.004	0.996	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.004	0.996	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.003	0.996	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.003	0.996	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.003	0.996	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.003	0.996	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.003	0.996	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.003	0.996	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.003	0.996	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.003	0.996	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.003	0.996	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.003	0.996	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.003	0.996	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.003	0.996	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.003	0.996	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.003	0.996	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.003	0.996	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.003	0.996	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.996	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.996	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.996	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.996	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.996	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.996	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.996	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.996	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.996	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.003	0.996	0.000
M21.78 Unequal limb length (acquired)-Other	0.003	0.996	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.003	0.996	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.003	0.996	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.003	0.996	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.003	0.996	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.003	0.996	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.003	0.996	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.004	0.996	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.003	0.996	0.000
M23.43 Loose body in knee-Med lig/oth men	0.004	0.996	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.003	0.996	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.003	0.996	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.003	0.996	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.003	0.996	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.003	0.996	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.003	0.996	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.003	0.996	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.003	0.996	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.003	0.996	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.003	0.996	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.003	0.996	0.000
M23.47 Loose body in knee-Capsular lig	0.003	0.996	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.003	0.996	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.996	0.004
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.003	0.996	0.000
M31.9 Necrotising vasculopathy, unspecified	0.003	0.996	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.003	0.997	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.003	0.997	0.000
S51.8 Open wound of other parts of forearm	0.000	0.997	0.003
D73 Diseases of spleen	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.003	0.997	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.003	0.997	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.003	0.997	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.003	0.997	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.003	0.997	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.003	0.997	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.003	0.997	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.003	0.997	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.003	0.997	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.997	0.003
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.003	0.997	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.003	0.997	0.000
F11 Mental and behavioural disorders due to use of opioids	0.000	0.997	0.003
I95.1 Orthostatic hypotension	0.000	0.997	0.003
M31.2 Lethal midline granuloma	0.003	0.997	0.000
D37.1 Stomach	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.003	0.997	0.000
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
M31.0 Hypersensitivity angiitis	0.003	0.997	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.997	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M23.07 Cystic meniscus-Capsular lig	0.003	0.997	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.00 Cystic meniscus (Multiple sites)	0.003	0.997	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M31.7 Microscopic polyangiitis	0.003	0.997	0.000
M31.1 Thrombotic microangiopathy	0.003	0.997	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
D73.1 Hypersplenism	0.003	0.997	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.003	0.997	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.003	0.997	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.997	0.001
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
F11.3 Withdrawal state	0.000	0.997	0.003
M21.2 Flexion deformity	0.002	0.997	0.001
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
D37.6 Liver, gallbladder and bile ducts	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.997	0.003
R40.2 Coma, unspecified	0.000	0.997	0.003
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
F11.1 Harmful use	0.000	0.997	0.003
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.997	0.000
D73.3 Abscess of spleen	0.003	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.997	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.997	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.997	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D73.4 Cyst of spleen	0.003	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.997	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.003	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.997	0.003
D37.9 Digestive organ, unspecified	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.997	0.003
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
F11.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F11.8 Other mental and behavioural disorders	0.000	0.997	0.003
F11.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F11.6 Amnesic syndrome	0.000	0.997	0.003
F11.5 Psychotic disorder	0.000	0.997	0.003
F11.4 Withdrawal state with delirium	0.000	0.997	0.003
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.997	0.003
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.997	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.997	0.003
D37.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.997	0.003
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.997	0.002
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
M24 Other specific joint derangements	0.002	0.997	0.000
D73.8 Other diseases of spleen	0.002	0.997	0.000
F11.0 Acute intoxication	0.000	0.997	0.002
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.998	0.002
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.998	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.001
M21.28 Flexion deformity (Other)	0.002	0.998	0.001
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.001
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.001
K09.9 Cyst of oral region, unspecified	0.000	0.998	0.002
N81.4 Uterovaginal prolapse, unspecified	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.000	0.998	0.002
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.001
F14.1 Harmful use	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.001
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.001
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.001
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
F17.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.001
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.000	0.998	0.002
M24.7 Protrusio acetabuli	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
F14.2 Dependence syndrome	0.000	0.998	0.002
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.998	0.002
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.998	0.002
O15 Eclampsia	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
F17.0 Acute intoxication	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
F17.8 Other mental and behavioural disorders	0.000	0.998	0.002
F17.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F17.6 Amnesic syndrome	0.000	0.998	0.002
F17.5 Psychotic disorder	0.000	0.998	0.002
F17.4 Withdrawal state with delirium	0.000	0.998	0.002
M24.6 Ankylosis of joint	0.002	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.001	0.998	0.001
F17.3 Withdrawal state	0.000	0.998	0.002
R02 Gangrene, not elsewhere classified	0.000	0.998	0.002
J20-J22 Other acute lower respiratory infections	0.000	0.998	0.002
F12.1 Harmful use	0.000	0.998	0.002
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.001	0.998	0.001
H61.0 Perichondritis of external ear	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.998	0.002
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.998	0.002
F14.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F14.8 Other mental and behavioural disorders	0.000	0.998	0.002
F14.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F14.6 Amnesic syndrome	0.000	0.998	0.002
F14.5 Psychotic disorder	0.000	0.998	0.002
F14.4 Withdrawal state with delirium	0.000	0.998	0.002
F14.3 Withdrawal state	0.000	0.998	0.002
F14.0 Acute intoxication	0.000	0.998	0.002
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
F13.2 Dependence syndrome	0.000	0.998	0.002
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.998	0.002
F13.1 Harmful use	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
F12.5 Psychotic disorder	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.002	0.998	0.000
F13.3 Withdrawal state	0.000	0.998	0.002
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
F12.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F12.8 Other mental and behavioural disorders	0.000	0.998	0.002
F12.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F12.6 Amnesic syndrome	0.000	0.998	0.002
F12.4 Withdrawal state with delirium	0.000	0.998	0.002
F12.3 Withdrawal state	0.000	0.998	0.002
F13.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F13.8 Other mental and behavioural disorders	0.000	0.998	0.002
F13.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F13.6 Amnesic syndrome	0.000	0.998	0.002
F13.5 Psychotic disorder	0.000	0.998	0.002
F13.4 Withdrawal state with delirium	0.000	0.998	0.002
F13.0 Acute intoxication	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.000	0.998	0.002
O14.2 HELLP syndrome	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
F12.2 Dependence syndrome	0.000	0.998	0.002
M84.3 Stress fracture, not elsewhere classified	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
F12.0 Acute intoxication	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
S20.2 Contusion of thorax	0.000	0.998	0.002
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
F15.1 Harmful use	0.000	0.998	0.002
F16.9 Unspecified mental and behavioural disorder	0.000	0.998	0.001
F16.8 Other mental and behavioural disorders	0.000	0.998	0.001
F16.7 Residual and late-onset psychotic disorder	0.000	0.998	0.001
F16.6 Amnesic syndrome	0.000	0.998	0.001
F16.5 Psychotic disorder	0.000	0.998	0.001
F16.4 Withdrawal state with delirium	0.000	0.998	0.001
F16.3 Withdrawal state	0.000	0.998	0.001
F16.2 Dependence syndrome	0.000	0.998	0.001
F16.1 Harmful use	0.000	0.998	0.001
F16.0 Acute intoxication	0.000	0.998	0.001
F18.9 Unspecified mental and behavioural disorder	0.000	0.998	0.001
F18.8 Other mental and behavioural disorders	0.000	0.998	0.001
F18.7 Residual and late-onset psychotic disorder	0.000	0.998	0.001
F18.6 Amnesic syndrome	0.000	0.998	0.001
F18.5 Psychotic disorder	0.000	0.998	0.001
F18.4 Withdrawal state with delirium	0.000	0.998	0.001
F18.3 Withdrawal state	0.000	0.998	0.001
F18.2 Dependence syndrome	0.000	0.998	0.001
F18.1 Harmful use	0.000	0.998	0.001
F18.0 Acute intoxication	0.000	0.998	0.001
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.998	0.000
F15.9 Unspecified mental and behavioural disorder	0.000	0.998	0.001
F15.8 Other mental and behavioural disorders	0.000	0.998	0.001
F15.7 Residual and late-onset psychotic disorder	0.000	0.998	0.001
F15.6 Amnesic syndrome	0.000	0.998	0.001
F15.5 Psychotic disorder	0.000	0.998	0.001
F15.4 Withdrawal state with delirium	0.000	0.998	0.001
F15.3 Withdrawal state	0.000	0.998	0.001
F15.2 Dependence syndrome	0.000	0.998	0.001
O12.0 Gestational oedema	0.002	0.998	0.000
S51 Open wound of forearm	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations