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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2721173
log Bayes Factor = 0.193726
Chromosome 8   position 145,744,429  (GRCh37) Explore rs2721173 on Ensembl!
Variant rs2721173 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.4 With neurological complications
0.000 0.691 0.309
E11 Non-insulin-dependent diabetes mellitus
0.000 0.700 0.300
E11.2 With renal complications
0.000 0.725 0.275
E11.3 With ophthalmic complications
0.000 0.731 0.269
E10-E14 Diabetes mellitus
0.000 0.732 0.268
E11.6 With other specified complications
0.000 0.739 0.261
E10 Insulin-dependent diabetes mellitus
0.000 0.745 0.255
E10.5 With peripheral circulatory complications
0.000 0.758 0.242
E10.1 With ketoacidosis
0.000 0.769 0.231
E13 Other specified diabetes mellitus
0.000 0.772 0.228
E11.0 With coma
0.000 0.774 0.226
E10.8 With unspecified complications
0.000 0.785 0.215
E11.7 With multiple complications
0.000 0.790 0.209
E10.4 With neurological complications
0.000 0.793 0.207
E13.9 Without complications
0.000 0.798 0.202
E10.6 With other specified complications
0.000 0.804 0.195
E14 Unspecified diabetes mellitus
0.000 0.805 0.195
E11.9 Without complications
0.000 0.805 0.195
E12 Malnutrition-related diabetes mellitus
0.000 0.808 0.192
E10.7 With multiple complications
0.000 0.818 0.182
E11.1 With ketoacidosis
0.000 0.820 0.180
E11.5 With peripheral circulatory complications
0.000 0.827 0.173
E11.8 With unspecified complications
0.000 0.832 0.168
E10.2 With renal complications
0.000 0.833 0.167
E13.8 With unspecified complications
0.000 0.836 0.163
E13.7 With multiple complications
0.000 0.836 0.163
E13.6 With other specified complications
0.000 0.836 0.163
E13.5 With peripheral circulatory complications
0.000 0.836 0.163
E13.4 With neurological complications
0.000 0.836 0.163
E13.2 With renal complications
0.000 0.836 0.163
E13.1 With ketoacidosis
0.000 0.836 0.163
E13.0 With coma
0.000 0.836 0.163
E10.0 With coma
0.000 0.837 0.162
E10.3 With ophthalmic complications
0.000 0.842 0.158
E14.4 With neurological complications
0.000 0.842 0.158
E14.2 Withrenal complications
0.000 0.843 0.157
E13.3 With ophthalmic complications
0.000 0.845 0.155
E14.6 With other specified complications
0.000 0.854 0.146
E14.8 With unspecified complications
0.000 0.855 0.145
E14.7 With multiple complications
0.000 0.860 0.140
E14.0 With coma
0.000 0.860 0.140
E14.1 With ketoacidosis
0.000 0.861 0.139
E14.3 With ophthalmic complications
0.000 0.861 0.139
E12.9 Without complications
0.000 0.862 0.138
E12.8 With unspecified complications
0.000 0.862 0.138
E12.7 With multiple complications
0.000 0.862 0.138
E12.6 With other specified complications
0.000 0.862 0.138
E12.5 With peripheral circulatory complications
0.000 0.862 0.138
E12.4 With neurological complications
0.000 0.862 0.138
E12.3 With ophthalmic complications
0.000 0.862 0.138
E12.2 With renal complications
0.000 0.862 0.138
E12.1 With ketoacidosis
0.000 0.862 0.138
E12.0 With coma
0.000 0.862 0.138
E14.5 With peripheral circulatory complications
0.000 0.881 0.118
E14.9 Without complications
0.000 0.900 0.100
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.922 0.078
K56.6 Other and unspecified intestinal obstruction
0.058 0.942 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.947 0.053
I42 Cardiomyopathy
0.000 0.947 0.053
I42.2 Other hypertrophic cardiomyopathy
0.000 0.948 0.052
K56 Paralytic ileus and intestinal obstruction without hernia
0.050 0.950 0.000
K56.2 Volvulus
0.050 0.950 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.048 0.952 0.000
I42.0 Dilated cardiomyopathy
0.000 0.954 0.046
I42.9 Cardiomyopathy, unspecified
0.000 0.956 0.044
I42.8 Other cardiomyopathies
0.000 0.957 0.043
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.957 0.043
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.960 0.040
E87.3 Alkalosis
0.000 0.961 0.039
I42.4 Endocardial fibroelastosis
0.000 0.962 0.038
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.962 0.038
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.962 0.037
E87.2 Acidosis
0.000 0.963 0.037
K56.7 Ileus, unspecified
0.037 0.963 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.963 0.037
E10.9 Without complications
0.000 0.963 0.037
K56.3 Gallstone ileus
0.036 0.963 0.000
I42.5 Other restrictive cardiomyopathy
0.000 0.965 0.035
E87.4 Mixed disorder of acid-base balance
0.000 0.969 0.031
E87.0 Hyperosmolality and hypernatraemia
0.000 0.972 0.028
K56.1 Intussusception
0.027 0.973 0.000
R39.1 Other difficulties with micturition
0.026 0.974 0.000
S42.40 Fracture of lower end of humerus (closed)
0.000 0.975 0.025
E87.5 Hyperkalaemia
0.000 0.976 0.024
K56.0 Paralytic ileus
0.023 0.977 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.022 0.978 0.000
K56.4 Other impaction of intestine
0.016 0.984 0.000
E87.6 Hypokalaemia
0.000 0.985 0.015
I50.9 Heart failure, unspecified
0.000 0.985 0.015
Q38.7 Pharyngeal pouch
0.013 0.987 0.000
I50.0 Congestive heart failure
0.000 0.987 0.013
I50 Heart failure
0.000 0.988 0.012
S42.4 Fracture of lower end of humerus
0.000 0.988 0.012
Q38 Other congenital malformations of tongue, mouth and pharynx
0.011 0.989 0.000
I45.9 Conduction disorder, unspecified
0.000 0.989 0.011
Q38.6 Other congenital malformations of mouth
0.011 0.989 0.000
Q43 Other congenital malformations of intestine
0.010 0.990 0.000
Q43.0 Meckel's diverticulum
0.009 0.991 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.991 0.009
I45 Other conduction disorders
0.000 0.991 0.009
I45.4 Nonspecific intraventricular block
0.000 0.991 0.009
H74 Other disorders of middle ear and mastoid
0.009 0.991 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.009 0.991 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.009 0.991 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.008 0.991 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.008 0.991 0.000
Q38.3 Other congenital malformations of tongue
0.008 0.991 0.000
Q38.2 Macroglossia
0.008 0.991 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.008 0.991 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.008 0.992 0.000
H74.4 Polyp of middle ear
0.008 0.992 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.992 0.008
Q43.9 Congenital malformation of intestine, unspecified
0.008 0.992 0.000
Z34.8 Supervision of other normal pregnancy
0.000 0.992 0.008
Q38.8 Other congenital malformations of pharynx
0.008 0.992 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.992 0.008
Q43.8 Other specified congenital malformations of intestine
0.008 0.992 0.000
M54.56 Low back pain (Lumbar region)
0.008 0.992 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.008 0.992 0.000
I45.8 Other specified conduction disorders
0.000 0.992 0.008
H74.2 Discontinuity and dislocation of ear ossicles
0.008 0.992 0.000
E87.7 Fluid overload
0.000 0.992 0.008
H74.0 Tympanosclerosis
0.008 0.992 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.992 0.008
Q43.3 Congenital malformations of intestinal fixation
0.007 0.993 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.007 0.993 0.000
I38 Endocarditis, valve unspecified
0.000 0.993 0.007
Q38.1 Ankyloglossia
0.007 0.993 0.000
I30-I52 Other forms of heart disease
0.000 0.993 0.007
S42.41 Fracture of lower end of humerus (open)
0.000 0.993 0.007
Q43.7 Persistent cloaca
0.007 0.993 0.000
Q43.6 Congenital fistula of rectum and anus
0.007 0.993 0.000
Q43.5 Ectopic anus
0.007 0.993 0.000
Q43.4 Duplication of intestine
0.007 0.993 0.000
Q43.2 Other congenital functional disorders of colon
0.007 0.993 0.000
E28 Ovarian dysfunction
0.000 0.993 0.007
I45.2 Bifascicular block
0.000 0.993 0.007
I45.0 Right fascicular block
0.000 0.993 0.007
H74.1 Adhesive middle ear disease
0.007 0.993 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.000 0.993 0.007
I45.3 Trifascicular block
0.000 0.993 0.007
C45.0 Mesothelioma of pleura
0.007 0.993 0.000
Q40 Other congenital malformations of upper alimentary tract
0.006 0.993 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.007 0.993 0.000
Q43.1 Hirschsprung's disease
0.006 0.993 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.006 0.994 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.006 0.994 0.000
R26 Abnormalities of gait and mobility
0.000 0.994 0.006
E65 Localised adiposity
0.000 0.994 0.006
C45.7 Mesothelioma of other sites
0.006 0.994 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.994 0.006
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.006 0.994 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.006 0.994 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.006 0.994 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.006 0.994 0.000
I40 Acute myocarditis
0.000 0.994 0.006
E28.3 Primary ovarian failure
0.000 0.994 0.006
C45 Mesothelioma
0.006 0.994 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.994 0.006
Q39 Congenital malformations of oesophagus
0.006 0.994 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.994 0.006
M81.90 Osteoporosis, unspecified (Multiple sites)
0.000 0.994 0.006
R26.0 Ataxic gait
0.000 0.994 0.006
G40 Epilepsy
0.006 0.994 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.006 0.994 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.994 0.006
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.006 0.994 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.006 0.994 0.000
I44.2 Atrioventricular block, complete
0.000 0.994 0.006
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.006 0.994 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.006 0.994 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.000 0.994 0.006
S06.2 Diffuse brain injury
0.000 0.994 0.006
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.994 0.006
S06 Intracranial injury
0.000 0.994 0.006
C45.9 Mesothelioma, unspecified
0.006 0.994 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.994 0.006
E40-E46 Malnutrition
0.000 0.994 0.006
Q40.1 Congenital hiatus hernia
0.005 0.994 0.000
I37 Pulmonary valve disorders
0.000 0.994 0.005
E70-E90 Metabolic disorders
0.000 0.994 0.006
S06.3 Focal brain injury
0.000 0.995 0.005
Q45 Other congenital malformations of digestive system
0.005 0.995 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.995 0.005
I52 Other heart disorders in diseases classified elsewhere
0.000 0.995 0.005
I48 Atrial fibrillation and flutter
0.000 0.995 0.005
I41 Myocarditis in diseases classified elsewhere
0.000 0.995 0.005
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.995 0.005
I32 Pericarditis in diseases classified elsewhere
0.000 0.995 0.005
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.005 0.995 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.005 0.995 0.000
Q40.8 Other specified congenital malformations of upper alimentary tract
0.005 0.995 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.995 0.005
E28.8 Other ovarian dysfunction
0.000 0.995 0.005
E28.1 Androgen excess
0.000 0.995 0.005
E28.0 Oestrogen excess
0.000 0.995 0.005
S06.5 Traumatic subdural haemorrhage
0.000 0.995 0.005
I44 Atrioventricular and left bundle-branch block
0.000 0.995 0.005
I44.4 Left anterior fascicular block
0.000 0.995 0.005
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.995 0.005
I40.9 Acute myocarditis, unspecified
0.000 0.995 0.005
E29 Testicular dysfunction
0.000 0.995 0.005
M81.98 Osteoporosis, unspecified (Other)
0.000 0.995 0.005
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.005 0.995 0.000
M80 Osteoporosis with pathological fracture
0.005 0.995 0.000
R39 Other symptoms and signs involving the urinary system
0.005 0.995 0.000
I40.0 Infective myocarditis
0.000 0.995 0.005
E26 Hyperaldosteronism
0.000 0.995 0.005
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.995 0.005
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.005 0.995 0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified
0.005 0.995 0.000
Q40.0 Congenital hypertrophic pyloric stenosis
0.005 0.995 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.005 0.995 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.005 0.995 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.005 0.995 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.005 0.995 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.005 0.995 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.005 0.995 0.000
S06.8 Other intracranial injuries
0.000 0.995 0.005
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified
0.005 0.995 0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine
0.005 0.995 0.000
Q41.2 Congenital absence, atresia and stenosis of ileum
0.005 0.995 0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum
0.005 0.995 0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum
0.005 0.995 0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified
0.005 0.995 0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine
0.005 0.995 0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula
0.005 0.995 0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula
0.005 0.995 0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula
0.005 0.995 0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula
0.005 0.995 0.000
R26.1 Paralytic gait
0.000 0.995 0.005
E27 Other disorders of adrenal gland
0.000 0.995 0.005
E31 Polyglandular dysfunction
0.000 0.995 0.005
R25.2 Cramp and spasm
0.000 0.995 0.005
G40.8 Other epilepsy
0.005 0.995 0.000
E67 Other hyperalimentation
0.000 0.995 0.005
E68 Sequelae of hyperalimentation
0.000 0.995 0.005
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.995 0.005
E20 Hypoparathyroidism
0.000 0.995 0.005
E79 Disorders of purine and pyrimidine metabolism
0.000 0.995 0.005
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)
0.000 0.995 0.005
S42 Fracture of shoulder and upper arm
0.000 0.995 0.005
Q44.7 Other congenital malformations of liver
0.005 0.995 0.000
I40.8 Other acute myocarditis
0.000 0.995 0.005
I40.1 Isolated myocarditis
0.000 0.995 0.005
C45.2 Mesothelioma of pericardium
0.005 0.995 0.000
C45.1 Mesothelioma of peritoneum
0.005 0.995 0.000
M81.9 Osteoporosis, unspecified
0.000 0.995 0.005
S42.7 Multiple fractures of clavicle, scapula and humerus
0.000 0.995 0.005
Q40.3 Congenital malformation of stomach, unspecified
0.004 0.995 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.995 0.005
E32 Diseases of thymus
0.000 0.995 0.005
E30 Disorders of puberty, not elsewhere classified
0.000 0.995 0.005
Q39.9 Congenital malformation of oesophagus, unspecified
0.004 0.995 0.000
Q39.8 Other congenital malformations of oesophagus
0.004 0.995 0.000
Q39.5 Congenital dilatation of oesophagus
0.004 0.995 0.000
Q39.3 Congenital stenosis and stricture of oesophagus
0.004 0.995 0.000
Q39.2 Congenital tracheooesophageal fistula without atresia
0.004 0.995 0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula
0.004 0.995 0.000
Q39.0 Atresia of oesophagus without fistula
0.004 0.995 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.004 0.995 0.000
Q44.2 Atresia of bile ducts
0.004 0.995 0.000
Q44.1 Other congenital malformations of gallbladder
0.004 0.995 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.004 0.995 0.000
S42.1 Fracture of scapula
0.000 0.995 0.004
S42.10 Fracture of scapula (closed)
0.000 0.995 0.004
M81.4 Drug-induced osteoporosis
0.000 0.995 0.004
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.995 0.004
I45.5 Other specified heart block
0.000 0.996 0.004
M80.5 Idiopathic osteoporosis with pathological fracture
0.004 0.996 0.000
Q39.4 Oesophageal web
0.004 0.996 0.000
S06.4 Epidural haemorrhage
0.000 0.996 0.004
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.996 0.004
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.004 0.996 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.996 0.004
E29.1 Testicular hypofunction
0.000 0.996 0.004
Q44.4 Choledochal cyst
0.004 0.996 0.000
E84 Cystic fibrosis
0.000 0.996 0.004
S06.7 Intracranial injury with prolonged coma
0.000 0.996 0.004
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.004 0.996 0.000
I44.3 Other and unspecified atrioventricular block
0.000 0.996 0.004
N18.0 End-stage renal disease
0.000 0.996 0.004
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.004
I37.1 Pulmonary valve insufficiency
0.000 0.996 0.004
Q39.6 Diverticulum of oesophagus
0.004 0.996 0.000
Q44.6 Cystic disease of liver
0.004 0.996 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.996 0.004
E45 Retarded development following protein-energy malnutrition
0.000 0.996 0.004
E43 Unspecified severe protein-energy malnutrition
0.000 0.996 0.004
E42 Marasmic kwashiorkor
0.000 0.996 0.004
E41 Nutritional marasmus
0.000 0.996 0.004
E40 Kwashiorkor
0.000 0.996 0.004
E26.0 Primary hyperaldosteronism
0.000 0.996 0.004
Q40.2 Other specified congenital malformations of stomach
0.004 0.996 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.996 0.004
I37.8 Other pulmonary valve disorders
0.000 0.996 0.004
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.996 0.004
E25 Adrenogenital disorders
0.000 0.996 0.004
E77 Disorders of glycoprotein metabolism
0.000 0.996 0.004
E76 Disorders of glycosaminoglycan metabolism
0.000 0.996 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.996 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.996 0.004
G40.4 Other generalised epilepsy and epileptic syndromes
0.004 0.996 0.000
Q44.5 Other congenital malformations of bile ducts
0.004 0.996 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.996 0.004
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.996 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.996 0.004
I37.0 Pulmonary valve stenosis
0.000 0.996 0.004
Q45.9 Congenital malformation of digestive system, unspecified
0.004 0.996 0.000
Q45.2 Congenital pancreatic cyst
0.004 0.996 0.000
Q45.1 Annular pancreas
0.004 0.996 0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas
0.004 0.996 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.996 0.004
E29.9 Testicular dysfunction, unspecified
0.000 0.996 0.004
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.996 0.004
G44.2 Tension-type headache
0.004 0.996 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.996 0.004
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.996 0.004
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.996 0.004
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.996 0.004
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.996 0.004
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.996 0.004
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.996 0.004
I48.4 Atypical atrial flutter
0.000 0.996 0.004
I48.3 Typical atrial flutter
0.000 0.996 0.004
I48.2 Chronic atrial fibrillation
0.000 0.996 0.004
I48.1 Persistent atrial fibrillation
0.000 0.996 0.004
I48.0 Paroxysmal atrial fibrillation
0.000 0.996 0.004
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.996 0.004
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.996 0.004
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.004 0.996 0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.004 0.996 0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.004 0.996 0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.004 0.996 0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.004 0.996 0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.004 0.996 0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.004 0.996 0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.004 0.996 0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.004 0.996 0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.004 0.996 0.000
S06.1 Traumatic cerebral oedema
0.000 0.996 0.004
E72 Other disorders of amino-acid metabolism
0.000 0.996 0.004
E27.8 Other specified disorders of adrenal gland
0.000 0.996 0.004
I36 Nonrheumatic tricuspid valve disorders
0.000 0.996 0.004
Z43.3 Attention to colostomy
0.004 0.996 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.996 0.004
M80.8 Other osteoporosis with pathological fracture
0.004 0.996 0.000
S06.9 Intracranial injury, unspecified
0.000 0.996 0.004
I44.5 Left posterior fascicular block
0.000 0.996 0.004
E26.9 Hyperaldosteronism, unspecified
0.000 0.996 0.004
S42.8 Fracture of other parts of shoulder and upper arm
0.000 0.996 0.004
E31.0 Autoimmune polyglandular failure
0.000 0.996 0.004
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.996 0.004
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.996 0.004
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
E20.9 Hypoparathyroidism, unspecified
0.000 0.996 0.004
E29.8 Other testicular dysfunction
0.000 0.996 0.004
E29.0 Testicular hyperfunction
0.000 0.996 0.004
M80.4 Drug-induced osteoporosis with pathological fracture
0.004 0.996 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.004 0.996 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.004 0.996 0.000
E26.8 Other hyperaldosteronism
0.000 0.996 0.004
E26.1 Secondary hyperaldosteronism
0.000 0.996 0.004
R39.2 Extrarenal uraemia
0.004 0.996 0.000
R39.0 Extravasation of urine
0.004 0.996 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.996 0.004
M54.5 Low back pain
0.004 0.996 0.000
E88 Other metabolic disorders
0.000 0.996 0.004
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.996 0.004
M81 Osteoporosis without pathological fracture
0.000 0.996 0.004
M81.93 Osteoporosis, unspecified (Forearm)
0.000 0.996 0.004
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.000 0.996 0.004
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.996 0.004
E27.5 Adrenomedullary hyperfunction
0.000 0.996 0.004
E27.0 Other adrenocortical overactivity
0.000 0.996 0.004
E31.9 Polyglandular dysfunction, unspecified
0.000 0.996 0.004
E31.8 Other polyglandular dysfunction
0.000 0.996 0.004
E31.1 Polyglandular hyperfunction
0.000 0.996 0.004
Q45.8 Other specified congenital malformations of digestive system
0.003 0.996 0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct
0.003 0.996 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.000 0.996 0.004
E67.8 Other specified hyperalimentation
0.000 0.996 0.003
E67.3 Hypervitaminosis D
0.000 0.996 0.003
E67.2 Megavitamin-B6 syndrome
0.000 0.996 0.003
E67.1 Hypercarotenaemia
0.000 0.996 0.003
E67.0 Hypervitaminosis A
0.000 0.996 0.003
S06.0 Concussion
0.000 0.996 0.004
E20.1 Pseudohypoparathyroidism
0.000 0.996 0.003
E20.0 Idiopathic hypoparathyroidism
0.000 0.996 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.996 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.996 0.003
E79.1 Lesch-Nyhan syndrome
0.000 0.996 0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.996 0.004
I44.6 Other and unspecified fascicular block
0.000 0.996 0.004
M81.92 Osteoporosis, unspecified (Upper arm)
0.000 0.996 0.003
M81.91 Osteoporosis, unspecified (Shoulder region)
0.000 0.996 0.003
S42.71 Multiple fractures of clavicle, scapula and humerus (open)
0.000 0.996 0.003
E30.9 Disorder of puberty, unspecified
0.000 0.996 0.003
E30.8 Other disorders of puberty
0.000 0.996 0.003
E30.1 Precocious puberty
0.000 0.996 0.003
E30.0 Delayed puberty
0.000 0.996 0.003
E32.9 Disease of thymus, unspecified
0.000 0.996 0.003
E32.8 Other diseases of thymus
0.000 0.996 0.003
E32.1 Abscess of thymus
0.000 0.996 0.003
E32.0 Persistent hyperplasia of thymus
0.000 0.996 0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.996 0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.996 0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.996 0.003
E46 Unspecified protein-energy malnutrition
0.000 0.996 0.004
E84.9 Cystic fibrosis, unspecified
0.000 0.996 0.003
S42.80 Fracture of other parts of shoulder and upper arm (closed)
0.000 0.996 0.003
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.996 0.003
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.003 0.996 0.000
S42.11 Fracture of scapula (open)
0.000 0.996 0.003
M81.48 Drug-induced osteoporosis (Other)
0.000 0.996 0.003
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.000 0.996 0.003
M81.46 Drug-induced osteoporosis (Lower leg)
0.000 0.996 0.003
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.000 0.996 0.003
M81.44 Drug-induced osteoporosis (Hand)
0.000 0.996 0.003
M81.43 Drug-induced osteoporosis (Forearm)
0.000 0.996 0.003
M81.42 Drug-induced osteoporosis (Upper arm)
0.000 0.996 0.003
M81.41 Drug-induced osteoporosis (Shoulder region)
0.000 0.996 0.003
E27.2 Addisonian crisis
0.000 0.996 0.003
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.003 0.997 0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.003 0.997 0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.003 0.997 0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.003 0.997 0.000
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.997 0.003
G40.5 Special epileptic syndromes
0.003 0.997 0.000
I33 Acute and subacute endocarditis
0.000 0.997 0.003
E20.8 Other hypoparathyroidism
0.000 0.997 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
E88.9 Metabolic disorder, unspecified
0.000 0.997 0.003
E84.8 Cystic fibrosis with other manifestations
0.000 0.997 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.997 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.997 0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.997 0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.997 0.003
E23 Hypofunction and other disorders of pituitary gland
0.000 0.997 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
E74.0 Glycogen storage disease
0.000 0.997 0.003
I45.6 Preexcitation syndrome
0.000 0.997 0.003
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000
E73 Lactose intolerance
0.000 0.997 0.003
E44.1 Mild protein-energy malnutrition
0.000 0.997 0.003
E44.0 Moderate protein-energy malnutrition
0.000 0.997 0.003
E25.9 Adrenogenital disorder, unspecified
0.000 0.997 0.003
E25.8 Other adrenogenital disorders
0.000 0.997 0.003
E71.3 Disorders of fatty-acid metabolism
0.000 0.997 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.997 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.997 0.003
E71.0 Maple-syrup-urine disease
0.000 0.997 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.997 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.997 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.997 0.003
E76.2 Other mucopolysaccharidoses
0.000 0.997 0.003
E76.1 Mucopolysaccharidosis, type II
0.000 0.997 0.003
E76.0 Mucopolysaccharidosis, type I
0.000 0.997 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.997 0.003
E77.8 Other disorders of glycoprotein metabolism
0.000 0.997 0.003
E77.1 Defects in glycoprotein degradation
0.000 0.997 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.997 0.003
E15 Nondiabetic hypoglycaemic coma
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.997 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
E70.2 Disorders of tyrosine metabolism
0.000 0.997 0.003
E70.1 Other hyperphenylalaninaemias
0.000 0.997 0.003
E70.0 Classical phenylketonuria
0.000 0.997 0.003
E75.6 Lipid storage disorder, unspecified
0.000 0.997 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.997 0.003
E75.3 Sphingolipidosis, unspecified
0.000 0.997 0.003
E75.2 Other sphingolipidosis
0.000 0.997 0.003
E75.1 Other gangliosidosis
0.000 0.997 0.003
E75.0 GM2 gangliosidosis
0.000 0.997 0.003
S62.8 Fracture of other and unspecified parts of wrist and hand
0.000 0.997 0.003
E70.3 Albinism
0.000 0.997 0.003
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.997 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.997 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.997 0.003
E72.5 Disorders of glycine metabolism
0.000 0.997 0.003
E72.4 Disorders of ornithine metabolism
0.000 0.997 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.997 0.003
E72.2 Disorders of urea cycle metabolism
0.000 0.997 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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