TreeWAS – Variant ID: rs2727261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N80.3 Endometriosis of pelvic peritoneum	0.000	0.897	0.103
N80.1 Endometriosis of ovary	0.000	0.898	0.102
N80 Endometriosis	0.000	0.899	0.101
N80.2 Endometriosis of Fallopian tube	0.000	0.905	0.095
N80.5 Endometriosis of intestine	0.000	0.914	0.085
N80.8 Other endometriosis	0.000	0.920	0.080
N80.4 Endometriosis of rectovaginal septum and vagina	0.000	0.922	0.078
N80.6 Endometriosis in cutaneous scar	0.000	0.931	0.069
N80.0 Endometriosis of uterus	0.000	0.953	0.047
N80.9 Endometriosis, unspecified	0.000	0.974	0.026
I49.5 Sick sinus syndrome	0.016	0.984	0.000
Z95.4 Presence of other heart-valve replacement	0.015	0.985	0.000
I49 Other cardiac arrhythmias	0.013	0.987	0.000
I49.4 Other and unspecified premature depolarisation	0.012	0.988	0.000
I30-I52 Other forms of heart disease	0.012	0.988	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.011	0.989	0.000
M07.3 Other psoriatic arthropathies	0.011	0.989	0.000
I38 Endocarditis, valve unspecified	0.011	0.989	0.000
I33 Acute and subacute endocarditis	0.011	0.989	0.000
I46 Cardiac arrest	0.011	0.989	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.011	0.989	0.000
I35 Nonrheumatic aortic valve disorders	0.011	0.989	0.000
I33.0 Acute and subacute infective endocarditis	0.011	0.989	0.000
I46.0 Cardiac arrest with successful resuscitation	0.011	0.989	0.000
I34 Nonrheumatic mitral valve disorders	0.011	0.989	0.000
I44.0 Atrioventricular block, first degree	0.010	0.990	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.990	0.010
I35.2 Aortic (valve) stenosis with insufficiency	0.010	0.990	0.000
I49.0 Ventricular fibrillation and flutter	0.010	0.990	0.000
I49.1 Atrial premature depolarisation	0.010	0.990	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.010	0.990	0.000
I49.2 Junctional premature depolarisation	0.010	0.990	0.000
I44 Atrioventricular and left bundle-branch block	0.010	0.990	0.000
I35.9 Aortic valve disorder, unspecified	0.010	0.990	0.000
I35.0 Aortic (valve) stenosis	0.009	0.991	0.000
I31 Other diseases of pericardium	0.009	0.991	0.000
I49.8 Other specified cardiac arrhythmias	0.009	0.991	0.000
I50 Heart failure	0.009	0.991	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.009	0.991	0.000
I40 Acute myocarditis	0.009	0.991	0.000
I31.9 Disease of pericardium, unspecified	0.009	0.991	0.000
I49.3 Ventricular premature depolarisation	0.009	0.991	0.000
I30 Acute pericarditis	0.009	0.991	0.000
M07.38 Other psoriatic arthropathies (Other)	0.009	0.991	0.000
I34.1 Mitral (valve) prolapse	0.009	0.991	0.000
I50.1 Left ventricular failure	0.009	0.991	0.000
I37 Pulmonary valve disorders	0.009	0.991	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.009	0.991	0.000
I52 Other heart disorders in diseases classified elsewhere	0.009	0.991	0.000
I48 Atrial fibrillation and flutter	0.009	0.991	0.000
I41 Myocarditis in diseases classified elsewhere	0.009	0.991	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I32 Pericarditis in diseases classified elsewhere	0.009	0.991	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.009	0.991	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.008	0.991	0.000
I44.1 Atrioventricular block, second degree	0.009	0.991	0.000
I46.1 Sudden cardiac death, so described	0.008	0.991	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.008	0.992	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.008	0.992	0.000
I36 Nonrheumatic tricuspid valve disorders	0.008	0.992	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.008	0.992	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.008	0.992	0.000
I33.9 Acute endocarditis, unspecified	0.008	0.992	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.008	0.992	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.008	0.992	0.000
I46.9 Cardiac arrest, unspecified	0.008	0.992	0.000
I34.0 Mitral (valve) insufficiency	0.008	0.992	0.000
I63.9 Cerebral infarction, unspecified	0.008	0.992	0.000
I31.1 Chronic constrictive pericarditis	0.007	0.992	0.000
I30.1 Infective pericarditis	0.007	0.993	0.000
I44.4 Left anterior fascicular block	0.007	0.993	0.000
I44.5 Left posterior fascicular block	0.007	0.993	0.000
I44.6 Other and unspecified fascicular block	0.007	0.993	0.000
I40.0 Infective myocarditis	0.007	0.993	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.007	0.993	0.000
I31.8 Other specified diseases of pericardium	0.007	0.993	0.000
I31.2 Haemopericardium, not elsewhere classified	0.007	0.993	0.000
I37.1 Pulmonary valve insufficiency	0.007	0.993	0.000
I50.0 Congestive heart failure	0.007	0.993	0.000
I40.9 Acute myocarditis, unspecified	0.007	0.993	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.007	0.993	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.993	0.007
I40.8 Other acute myocarditis	0.007	0.993	0.000
I40.1 Isolated myocarditis	0.007	0.993	0.000
I30.9 Acute pericarditis, unspecified	0.007	0.993	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.007	0.993	0.000
I35.8 Other aortic valve disorders	0.006	0.993	0.000
I37.9 Pulmonary valve disorder, unspecified	0.006	0.993	0.000
I37.8 Other pulmonary valve disorders	0.006	0.993	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.006	0.993	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.006	0.993	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.006	0.993	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.006	0.993	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.006	0.993	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.006	0.993	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.006	0.993	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.006	0.993	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.006	0.993	0.000
I48.4 Atypical atrial flutter	0.006	0.993	0.000
I48.3 Typical atrial flutter	0.006	0.993	0.000
I48.2 Chronic atrial fibrillation	0.006	0.993	0.000
I48.1 Persistent atrial fibrillation	0.006	0.993	0.000
I48.0 Paroxysmal atrial fibrillation	0.006	0.993	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.006	0.993	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.006	0.993	0.000
I08.0 Disorders of both mitral and aortic valves	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.006	0.994	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.006	0.994	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.006	0.994	0.000
I30.8 Other forms of acute pericarditis	0.006	0.994	0.000
I37.0 Pulmonary valve stenosis	0.006	0.994	0.000
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
Z95.3 Presence of xenogenic heart valve	0.006	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.994	0.000
I45 Other conduction disorders	0.006	0.994	0.000
I44.3 Other and unspecified atrioventricular block	0.006	0.994	0.000
I80 Phlebitis and thrombophlebitis	0.006	0.994	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.005	0.995	0.000
I08 Multiple valve diseases	0.005	0.995	0.000
N32.0 Bladder-neck obstruction	0.000	0.995	0.005
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.005	0.995	0.000
M07 Psoriatic and enteropathic arthropathies	0.005	0.995	0.000
I45.2 Bifascicular block	0.005	0.995	0.000
D68.9 Coagulation defect, unspecified	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.005	0.995	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.005	0.995	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.005	0.995	0.000
I45.4 Nonspecific intraventricular block	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
I45.3 Trifascicular block	0.005	0.995	0.000
D68.2 Hereditary deficiency of other clotting factors	0.005	0.995	0.000
I45.9 Conduction disorder, unspecified	0.004	0.995	0.000
I45.8 Other specified conduction disorders	0.004	0.996	0.000
I31.3 Pericardial effusion (noninflammatory)	0.004	0.996	0.000
I45.0 Right fascicular block	0.004	0.996	0.000
Z95.2 Presence of prosthetic heart valve	0.004	0.996	0.000
Z95.0 Presence of cardiac pacemaker	0.004	0.996	0.000
Z40 Prophylactic surgery	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.004	0.996	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.996	0.004
I63 Cerebral infarction	0.004	0.996	0.000
I08.8 Other multiple valve diseases	0.004	0.996	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.004	0.996	0.000
F20.9 Schizophrenia, unspecified	0.000	0.996	0.004
I08.9 Multiple valve disease, unspecified	0.004	0.996	0.000
M07.5 Arthropathy in ulcerative colitis	0.004	0.996	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.004	0.996	0.000
M07.2 Psoriatic spondylitis	0.004	0.996	0.000
M07.1 Arthritis mutilans	0.004	0.996	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.004	0.996	0.000
I49.9 Cardiac arrhythmia, unspecified	0.004	0.996	0.000
M07.6 Other enteropathic arthropathies	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
D68.6 Other Thrombophilia	0.004	0.996	0.000
I05-I09 Chronic rheumatic heart diseases	0.004	0.996	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.004	0.996	0.000
I50.9 Heart failure, unspecified	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
S00.1 Contusion of eyelid and periocular area	0.004	0.996	0.000
I45.5 Other specified heart block	0.003	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.996	0.000
I45.6 Preexcitation syndrome	0.003	0.996	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.004	0.996	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.003	0.996	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
Z40.8 Other prophylactic surgery	0.000	0.997	0.003
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.003	0.997	0.000
D48.1 Connective and other soft tissue	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
Z40.9 Prophylactic surgery, unspecified	0.000	0.997	0.003
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
I63.8 Other cerebral infarction	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.000	0.997	0.003
I35.1 Aortic (valve) insufficiency	0.003	0.997	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.003	0.997	0.000
F20 Schizophrenia	0.000	0.997	0.003
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
I06 Rheumatic aortic valve diseases	0.003	0.997	0.000
K80 Cholelithiasis	0.000	0.997	0.003
M67.8 Other specified disorders of synovium and tendon	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.000	0.997	0.003
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.003	0.997	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.003	0.997	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.003	0.997	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.003	0.997	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.003	0.997	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.003	0.997	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.003	0.997	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.003	0.997	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.003	0.997	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.003	0.997	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.003	0.997	0.000
M07.18 Arthritis mutilans (Other)	0.003	0.997	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.003	0.997	0.000
M07.16 Arthritis mutilans (Lower leg)	0.003	0.997	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.003	0.997	0.000
M07.14 Arthritis mutilans (Hand)	0.003	0.997	0.000
M07.13 Arthritis mutilans (Forearm)	0.003	0.997	0.000
M07.12 Arthritis mutilans (Upper arm)	0.003	0.997	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.003	0.997	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.003	0.997	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.003	0.997	0.000
M07.28 Psoriatic spondylitis (Other)	0.003	0.997	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.003	0.997	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.003	0.997	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.003	0.997	0.000
M07.24 Psoriatic spondylitis (Hand)	0.003	0.997	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.003	0.997	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.003	0.997	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.003	0.997	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.003	0.997	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.003	0.997	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.003	0.997	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.003	0.997	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.003	0.997	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.003	0.997	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.003	0.997	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.003	0.997	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.003	0.997	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.003	0.997	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.003	0.997	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.003	0.997	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.003	0.997	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.003	0.997	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.003	0.997	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.003	0.997	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.003	0.997	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.003	0.997	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.003	0.997	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.003	0.997	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.003	0.997	0.000
M07.68 Other enteropathic arthropathies (Other)	0.003	0.997	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.003	0.997	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.003	0.997	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.003	0.997	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.003	0.997	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.003	0.997	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.003	0.997	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.000	0.997	0.003
M07.69 Other enteropathic arthropathies (Site unspecified)	0.003	0.997	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.997	0.003
S00 Superficial injury of head	0.003	0.997	0.000
D39.1 Ovary	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.003
S00.3 Superficial injury of nose	0.003	0.997	0.000
I09 Other rheumatic heart diseases	0.003	0.997	0.000
R21 Rash and other nonspecific skin eruption	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.003	0.997	0.000
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.997	0.003
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.003	0.997	0.000
F20.8 Other schizophrenia	0.000	0.997	0.003
I47 Paroxysmal tachycardia	0.003	0.997	0.000
K83.0 Cholangitis	0.000	0.997	0.003
S00.9 Superficial injury of head, part unspecified	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.002	0.997	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.997	0.003
D48.6 Breast	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.000	0.997	0.002
F20.6 Simple schizophrenia	0.000	0.997	0.002
F20.4 Postschizophrenic depression	0.000	0.997	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.997	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.997	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.002	0.997	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.997	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.997	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.997	0.003
K80.3 Calculus of bile duct with cholangitis	0.000	0.997	0.002
D66 Hereditary factor VIII deficiency	0.002	0.997	0.000
I60.8 Other subarachnoid haemorrhage	0.002	0.997	0.000
L40.5 Arthropathic psoriasis	0.002	0.997	0.000
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.000	0.998	0.002
S00.5 Superficial injury of lip and oral cavity	0.002	0.998	0.000
K80.8 Other cholelithiasis	0.000	0.998	0.002
S00.0 Superficial injury of scalp	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
K08.3 Retained dental root	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.998	0.002
D39.0 Uterus	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.998	0.002
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.998	0.002
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.998	0.002
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
O02.1 Missed abortion	0.000	0.998	0.002
S00.4 Superficial injury of ear	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
I47.0 Reentry ventricular arrhythmia	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.000	0.998	0.002
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.002	0.998	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.998	0.002
N75 Diseases of Bartholin's gland	0.002	0.998	0.000
Chapter IX Diseases of the circulatory system	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
D45 Polycythaemia vera	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
N41 Inflammatory diseases of prostate	0.000	0.998	0.002
I47.9 Paroxysmal tachycardia, unspecified	0.002	0.998	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.001	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
I42.5 Other restrictive cardiomyopathy	0.001	0.998	0.000
N64.1 Fat necrosis of breast	0.000	0.998	0.002
Z60.2 Living alone	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.002	0.998	0.000
F52.2 Failure of genital response	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.001	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.001
N41.1 Chronic prostatitis	0.000	0.998	0.002
I28 Other diseases of pulmonary vessels	0.001	0.998	0.000
I00-I02 Acute rheumatic fever	0.001	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
I42.1 Obstructive hypertrophic cardiomyopathy	0.001	0.998	0.000
N75.8 Other diseases of Bartholin's gland	0.001	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.001
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.001	0.998	0.000
N18 Chronic renal failure	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.002	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
N41.3 Prostatocystitis	0.000	0.998	0.001
N41.2 Abscess of prostate	0.000	0.998	0.001
N75.9 Disease of Bartholin's gland, unspecified	0.001	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.998	0.001
Z86.7 Personal history of diseases of the circulatory system	0.002	0.998	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
I42.8 Other cardiomyopathies	0.001	0.998	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.998	0.001
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.001	0.998	0.000
M54.50 Low back pain (Multiple sites in spine)	0.001	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.001	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.001
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.000	0.998	0.001
S62.3 Fracture of other metacarpal bone	0.001	0.998	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.001
I42.6 Alcoholic cardiomyopathy	0.001	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
W25.9 Unspecified place	0.001	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.001	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.001
M25.46 Effusion of joint (Lower leg)	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.001	0.999	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.001	0.999	0.000
D37.6 Liver, gallbladder and bile ducts	0.001	0.999	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.999	0.000
M54.5 Low back pain	0.001	0.999	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.999	0.001
D46 Myelodysplastic syndromes	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.999	0.001
S64.0 Injury of ulnar nerve at wrist and hand level	0.001	0.999	0.000
I68.0 Cerebral amyloid angiopathy	0.001	0.999	0.000
M54.55 Low back pain (Thoracolumbar region)	0.001	0.999	0.000
D38.0 Larynx	0.001	0.999	0.000
D42.9 Meninges, unspecified	0.001	0.999	0.000
I28.1 Aneurysm of pulmonary artery	0.001	0.999	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.999	0.001
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.001	0.999	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.000	0.999	0.001
C83.1 Small cleaved cell (diffuse)	0.000	0.999	0.001
F25.9 Schizoaffective disorder, unspecified	0.000	0.999	0.001
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
R45.1 Restlessness and agitation	0.000	0.999	0.001
V17.0 Driver injured in nontraffic accident	0.000	0.999	0.001
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.001	0.999	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.001	0.999	0.000
I02 Rheumatic chorea	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations