TreeWAS – Variant ID: rs2734574

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.3 With ophthalmic complications	0.998	0.002	0.000
E83.1 Disorders of iron metabolism	0.000	0.008	0.992
M06 Other rheumatoid arthritis	0.980	0.020	0.000
E10.2 With renal complications	0.966	0.034	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.961	0.039	0.000
E14 Unspecified diabetes mellitus	0.959	0.041	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.958	0.042	0.000
E10.1 With ketoacidosis	0.952	0.048	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.951	0.049	0.000
M45 Ankylosing spondylitis	0.936	0.064	0.000
E16 Other disorders of pancreatic internal secretion	0.933	0.067	0.000
E20-E35 Disorders of other endocrine glands	0.929	0.071	0.000
E06 Thyroiditis	0.924	0.076	0.000
E14.3 With ophthalmic complications	0.919	0.081	0.000
M06.0 Seronegative rheumatoid arthritis	0.912	0.088	0.000
E16.2 Hypoglycaemia, unspecified	0.909	0.091	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.907	0.093	0.000
E27 Other disorders of adrenal gland	0.897	0.103	0.000
E27.1 Primary adrenocortical insufficiency	0.893	0.107	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.890	0.110	0.000
E06.3 Autoimmune thyroiditis	0.890	0.110	0.000
E10.4 With neurological complications	0.874	0.126	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.873	0.127	0.000
E22 Hyperfunction of pituitary gland	0.871	0.129	0.000
M06.4 Inflammatory polyarthropathy	0.862	0.138	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.861	0.139	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.852	0.148	0.000
M06.3 Rheumatoid nodule	0.841	0.159	0.000
E10.0 With coma	0.827	0.173	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.825	0.175	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.819	0.181	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.816	0.184	0.000
E40-E46 Malnutrition	0.814	0.186	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.810	0.190	0.000
E10.7 With multiple complications	0.794	0.206	0.000
M35.0 Sicca syndrome [Sjogren]	0.790	0.210	0.000
E23 Hypofunction and other disorders of pituitary gland	0.779	0.221	0.000
E14.2 Withrenal complications	0.778	0.222	0.000
E13 Other specified diabetes mellitus	0.775	0.225	0.000
M06.1 Adult-onset Still's disease	0.765	0.235	0.000
M06.34 Rheumatoid nodule (Hand)	0.761	0.239	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.756	0.244	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.756	0.244	0.000
E14.1 With ketoacidosis	0.755	0.244	0.000
M35 Other systemic involvement of connective tissue	0.754	0.246	0.000
E07 Other disorders of thyroid	0.750	0.250	0.000
E24 Cushing's syndrome	0.750	0.250	0.000
E04 Other non-toxic goitre	0.748	0.252	0.000
E10.6 With other specified complications	0.740	0.260	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.739	0.261	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.739	0.261	0.000
M06.8 Other specified rheumatoid arthritis	0.738	0.262	0.000
M35.3 Polymyalgia rheumatica	0.737	0.263	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.734	0.266	0.000
E14.6 With other specified complications	0.721	0.279	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.719	0.281	0.000
E31 Polyglandular dysfunction	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E05.8 Other thyrotoxicosis	0.717	0.283	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.713	0.287	0.000
E14.8 With unspecified complications	0.709	0.291	0.000
E10.8 With unspecified complications	0.707	0.293	0.000
E04.9 Non-toxic goitre, unspecified	0.705	0.295	0.000
M06.2 Rheumatoid bursitis	0.703	0.297	0.000
E06.5 Other chronic thyroiditis	0.693	0.307	0.000
E22.0 Acromegaly and pituitary gigantism	0.692	0.308	0.000
E27.9 Disorder of adrenal gland, unspecified	0.691	0.309	0.000
E15 Nondiabetic hypoglycaemic coma	0.689	0.311	0.000
E14.7 With multiple complications	0.688	0.312	0.000
E14.0 With coma	0.688	0.312	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.684	0.316	0.000
E23.6 Other disorders of pituitary gland	0.682	0.318	0.000
E46 Unspecified protein-energy malnutrition	0.681	0.319	0.000
E23.2 Diabetes insipidus	0.681	0.319	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.679	0.321	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.671	0.329	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.671	0.329	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.671	0.329	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.671	0.329	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.671	0.329	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.671	0.329	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.669	0.331	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.669	0.331	0.000
E16.4 Abnormal secretion of gastrin	0.669	0.331	0.000
E16.3 Increased secretion of glucagon	0.669	0.331	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.668	0.332	0.000
E28 Ovarian dysfunction	0.667	0.333	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.666	0.334	0.000
E32 Diseases of thymus	0.666	0.334	0.000
E30 Disorders of puberty, not elsewhere classified	0.666	0.334	0.000
E16.1 Other hypoglycaemia	0.663	0.337	0.000
E06.4 Drug-induced thyroiditis	0.662	0.338	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.662	0.338	0.000
E06.1 Subacute thyroiditis	0.662	0.338	0.000
E06.0 Acute thyroiditis	0.662	0.338	0.000
E14.5 With peripheral circulatory complications	0.662	0.338	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.662	0.338	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.660	0.339	0.000
E07.8 Other specified disorders of thyroid	0.660	0.340	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.654	0.346	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.654	0.346	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.654	0.346	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.654	0.346	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.654	0.346	0.000
E14.4 With neurological complications	0.648	0.352	0.000
K90 Intestinal malabsorption	0.647	0.353	0.000
E27.5 Adrenomedullary hyperfunction	0.643	0.357	0.000
E27.0 Other adrenocortical overactivity	0.643	0.357	0.000
E13.9 Without complications	0.631	0.369	0.000
E24.2 Drug-induced Cushing's syndrome	0.631	0.369	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.624	0.375	0.000
E22.8 Other hyperfunction of pituitary gland	0.624	0.375	0.000
E03.8 Other specified hypothyroidism	0.619	0.381	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.618	0.382	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.618	0.382	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.618	0.382	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.618	0.382	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.618	0.382	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.618	0.382	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.618	0.382	0.000
E22.1 Hyperprolactinaemia	0.616	0.384	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.611	0.389	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.603	0.397	0.000
M06.38 Rheumatoid nodule (Other)	0.603	0.397	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.603	0.397	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.603	0.397	0.000
M06.33 Rheumatoid nodule (Forearm)	0.603	0.397	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.603	0.397	0.000
E04.0 Non-toxic diffuse goitre	0.597	0.403	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.595	0.405	0.000
M05-M14 Inflammatory polyarthropathies	0.591	0.409	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.589	0.410	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.589	0.411	0.000
E25 Adrenogenital disorders	0.587	0.413	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.584	0.416	0.000
E45 Retarded development following protein-energy malnutrition	0.584	0.416	0.000
E43 Unspecified severe protein-energy malnutrition	0.584	0.416	0.000
E42 Marasmic kwashiorkor	0.584	0.416	0.000
E41 Nutritional marasmus	0.584	0.416	0.000
E40 Kwashiorkor	0.584	0.416	0.000
M35.1 Other overlap syndromes	0.579	0.421	0.000
E14.9 Without complications	0.578	0.422	0.000
E03.1 Congenital hypothyroidism without goitre	0.572	0.428	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.572	0.428	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.571	0.428	0.000
E31.0 Autoimmune polyglandular failure	0.568	0.432	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.564	0.436	0.000
E26 Hyperaldosteronism	0.559	0.441	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.559	0.441	0.000
E23.1 Drug-induced hypopituitarism	0.559	0.441	0.000
E27.2 Addisonian crisis	0.557	0.442	0.000
E13.8 With unspecified complications	0.556	0.444	0.000
E13.7 With multiple complications	0.556	0.444	0.000
E13.6 With other specified complications	0.556	0.444	0.000
E13.5 With peripheral circulatory complications	0.556	0.444	0.000
E13.4 With neurological complications	0.556	0.444	0.000
E13.2 With renal complications	0.556	0.444	0.000
E13.1 With ketoacidosis	0.556	0.444	0.000
E13.0 With coma	0.556	0.444	0.000
E24.0 Pituitary-dependent Cushing's disease	0.549	0.451	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.549	0.451	0.000
M06.18 Adult-onset Still's disease (Other)	0.549	0.451	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.549	0.451	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.549	0.451	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.549	0.451	0.000
M06.14 Adult-onset Still's disease (Hand)	0.549	0.451	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.549	0.451	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.549	0.451	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.549	0.451	0.000
E20 Hypoparathyroidism	0.548	0.451	0.000
M35.2 Behcet's disease	0.546	0.454	0.000
G35 Multiple sclerosis	0.000	0.458	0.542
M35.9 Systemic involvement of connective tissue, unspecified	0.541	0.459	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.541	0.459	0.000
M35.5 Multifocal fibrosclerosis	0.541	0.459	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.541	0.459	0.000
E28.3 Primary ovarian failure	0.538	0.462	0.000
E07.1 Dyshormogenetic goitre	0.537	0.462	0.000
E07.0 Hypersecretion of calcitonin	0.537	0.462	0.000
E24.8 Other Cushing's syndrome	0.537	0.462	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.537	0.462	0.000
E24.3 Ectopic ACTH syndrome	0.537	0.462	0.000
E24.1 Nelson's syndrome	0.537	0.462	0.000
E04.8 Other specified non-toxic goitre	0.536	0.464	0.000
E13.3 With ophthalmic complications	0.530	0.470	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.529	0.471	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.529	0.471	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.529	0.471	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.529	0.471	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.529	0.471	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.529	0.471	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.529	0.471	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.529	0.471	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.529	0.471	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.528	0.471	0.000
M45-M49 Spondylopathies	0.525	0.475	0.000
E10.5 With peripheral circulatory complications	0.520	0.480	0.000
E31.9 Polyglandular dysfunction, unspecified	0.515	0.485	0.000
E31.8 Other polyglandular dysfunction	0.515	0.485	0.000
E31.1 Polyglandular hyperfunction	0.515	0.485	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.511	0.489	0.000
K90.9 Intestinal malabsorption, unspecified	0.509	0.491	0.000
E24.9 Cushing's syndrome, unspecified	0.507	0.492	0.000
M35.7 Hypermobility syndrome	0.507	0.493	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.506	0.494	0.000
M20-M25 Other joint disorders	0.506	0.494	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.506	0.494	0.000
E23.7 Disorder of pituitary gland, unspecified	0.505	0.495	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.504	0.496	0.000
M06.28 Rheumatoid bursitis (Other)	0.504	0.496	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.504	0.496	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.504	0.496	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.504	0.496	0.000
M06.24 Rheumatoid bursitis (Hand)	0.504	0.496	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.504	0.496	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.504	0.496	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.504	0.496	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.504	0.496	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.502	0.498	0.000
M08 Juvenile arthritis	0.501	0.499	0.000
E29 Testicular dysfunction	0.496	0.503	0.000
M34 Systemic sclerosis	0.492	0.508	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.484	0.516	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.517	0.483
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.482	0.518	0.000
M10 Gout	0.479	0.521	0.000
E28.9 Ovarian dysfunction, unspecified	0.478	0.522	0.000
E28.8 Other ovarian dysfunction	0.478	0.522	0.000
E28.1 Androgen excess	0.478	0.522	0.000
E28.0 Oestrogen excess	0.478	0.522	0.000
E30.9 Disorder of puberty, unspecified	0.477	0.522	0.000
E30.8 Other disorders of puberty	0.477	0.522	0.000
E30.1 Precocious puberty	0.477	0.522	0.000
E30.0 Delayed puberty	0.477	0.522	0.000
E32.9 Disease of thymus, unspecified	0.477	0.522	0.000
E32.8 Other diseases of thymus	0.477	0.522	0.000
E32.1 Abscess of thymus	0.477	0.522	0.000
E32.0 Persistent hyperplasia of thymus	0.477	0.522	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.477	0.522	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.477	0.522	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.477	0.522	0.000
C85.1 B-cell lymphoma, unspecified	0.476	0.524	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.472	0.528	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.468	0.532	0.000
E27.8 Other specified disorders of adrenal gland	0.465	0.534	0.000
K90.3 Pancreatic steatorrhoea	0.464	0.536	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.464	0.536	0.000
K90.1 Tropical sprue	0.464	0.536	0.000
E50-E64 Other nutritional deficiencies	0.463	0.537	0.000
C83.3 Large cell (diffuse)	0.463	0.537	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.462	0.538	0.000
M35.8 Other specified systemic involvement of connective tissue	0.460	0.540	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.541	0.459
K90.8 Other intestinal malabsorption	0.457	0.543	0.000
C81 Hodgkin's disease	0.454	0.546	0.000
M34.1 CR(E)ST syndrome	0.451	0.549	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.550	0.450
M12 Other specific arthropathies	0.448	0.552	0.000
E06.9 Thyroiditis, unspecified	0.444	0.556	0.000
M34.9 Systemic sclerosis, unspecified	0.431	0.569	0.000
C81.9 Hodgkin's disease, unspecified	0.427	0.573	0.000
E34 Other endocrine disorders	0.425	0.574	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.426	0.574	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.424	0.576	0.000
E25.9 Adrenogenital disorder, unspecified	0.421	0.579	0.000
E25.8 Other adrenogenital disorders	0.421	0.579	0.000
E44.1 Mild protein-energy malnutrition	0.419	0.581	0.000
E44.0 Moderate protein-energy malnutrition	0.419	0.581	0.000
E26.9 Hyperaldosteronism, unspecified	0.418	0.582	0.000
M32 Systemic lupus erythematosus	0.410	0.590	0.000
L40.9 Psoriasis, unspecified	0.000	0.595	0.405
M08.9 Juvenile arthritis, unspecified	0.401	0.598	0.000
E26.8 Other hyperaldosteronism	0.401	0.599	0.000
E26.1 Secondary hyperaldosteronism	0.401	0.599	0.000
M34.8 Other forms of systemic sclerosis	0.399	0.601	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.395	0.605	0.000
M05 Seropositive rheumatoid arthritis	0.394	0.606	0.000
E20.8 Other hypoparathyroidism	0.393	0.606	0.000
E20.1 Pseudohypoparathyroidism	0.393	0.606	0.000
E20.0 Idiopathic hypoparathyroidism	0.393	0.606	0.000
M10.0 Idiopathic gout	0.392	0.608	0.000
M08.0 Juvenile rheumatoid arthritis	0.392	0.608	0.000
E28.2 Polycystic ovarian syndrome	0.390	0.610	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.388	0.612	0.000
M08.2 Juvenile arthritis with systemic onset	0.380	0.620	0.000
E58 Dietary calcium deficiency	0.376	0.624	0.000
C81.1 Nodular sclerosis	0.375	0.625	0.000
C88 Malignant immunoproliferative diseases	0.370	0.630	0.000
C84.0 Mycosis fungoides	0.367	0.633	0.000
M34.0 Progressive systemic sclerosis	0.363	0.637	0.000
G36 Other acute disseminated demyelination	0.000	0.639	0.361
E29.9 Testicular dysfunction, unspecified	0.361	0.639	0.000
C83.7 Burkitt's tumour	0.361	0.639	0.000
M14 Arthropathies in other diseases classified elsewhere	0.360	0.639	0.000
C84.5 Other and unspecified T-cell lymphomas	0.360	0.640	0.000
M08.8 Other juvenile arthritis	0.359	0.641	0.000
M08.4 Pauciarticular juvenile arthritis	0.359	0.641	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.359	0.641	0.000
M08.1 Juvenile ankylosing spondylitis	0.359	0.641	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.356	0.643	0.000
E29.8 Other testicular dysfunction	0.356	0.644	0.000
E29.0 Testicular hyperfunction	0.356	0.644	0.000
# Top node	0.355	0.645	0.000
M10.9 Gout, unspecified	0.354	0.646	0.000
E63 Other nutritional deficiencies	0.354	0.646	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.353	0.647	0.000
M11 Other crystal arthropathies	0.349	0.650	0.000
M30 Polyarteritis nodosa and related conditions	0.349	0.650	0.000
E51 Thiamine deficiency	0.349	0.651	0.000
C81.2 Mixed cellularity	0.347	0.653	0.000
M31 Other necrotising vasculopathies	0.346	0.654	0.000
C85.0 Lymphosarcoma	0.346	0.654	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.345	0.655	0.000
M12.5 Traumatic arthropathy	0.345	0.655	0.000
M40-M43 Deforming dorsopathies	0.345	0.655	0.000
M10.4 Other secondary gout	0.344	0.656	0.000
M10.3 Gout due to impairment of renal function	0.344	0.656	0.000
M10.2 Drug-induced gout	0.344	0.656	0.000
M10.1 Lead-induced gout	0.344	0.656	0.000
C86 Other specified types of T/NK-cell lymphoma	0.343	0.657	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.342	0.658	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.342	0.658	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.339	0.661	0.000
C94 Other leukaemias of specified cell type	0.339	0.661	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.338	0.662	0.000
E23.0 Hypopituitarism	0.337	0.663	0.000
C83.1 Small cleaved cell (diffuse)	0.335	0.665	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.334	0.666	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.332	0.668	0.000
E50 Vitamin A deficiency	0.332	0.668	0.000
E60 Dietary zinc deficiency	0.332	0.668	0.000
E59 Dietary selenium deficiency	0.332	0.668	0.000
E52 Niacin deficiency [pellagra]	0.332	0.668	0.000
C81.0 Lymphocytic predominance	0.332	0.668	0.000
D60-D64 Aplastic and other anaemias	0.332	0.668	0.000
C83.6 Undifferentiated (diffuse)	0.332	0.668	0.000
C83.5 Lymphoblastic (diffuse)	0.332	0.668	0.000
C83.4 Immunoblastic (diffuse)	0.332	0.668	0.000
C83.2 Mixed small and large cell (diffuse)	0.332	0.668	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.332	0.668	0.000
Chapter II Neoplasms	0.331	0.669	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.331	0.669	0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.330	0.670	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.671	0.329
G37.4 Subacute necrotising myelitis	0.000	0.671	0.329
G37.2 Central pontine myelinolysis	0.000	0.671	0.329
G37.1 Central demyelination of corpus callosum	0.000	0.671	0.329
G37.0 Diffuse sclerosis	0.000	0.671	0.329
Q60-Q64 Congenital malformations of the urinary system	0.329	0.671	0.000
E07.9 Disorder of thyroid, unspecified	0.328	0.672	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.327	0.673	0.000
C81.7 Other Hodgkin's disease	0.326	0.673	0.000
E54 Ascorbic acid deficiency	0.326	0.674	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.326	0.674	0.000
C81.3 Lymphocytic depletion	0.326	0.674	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.323	0.677	0.000
M12.4 Intermittent hydrarthrosis	0.321	0.678	0.000
M12.1 Kaschin-Beck disease	0.321	0.678	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.321	0.678	0.000
Chapter I Certain infectious and parasitic diseases	0.321	0.679	0.000
M10.94 Gout, unspecified (Hand)	0.321	0.679	0.000
M91-M94 Chondropathies	0.320	0.679	0.000
M80-M85 Disorders of bone density and structure	0.320	0.680	0.000
M12.2 Villonodular synovitis (pigmented)	0.320	0.680	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.319	0.681	0.000
M10.00 Idiopathic gout (Multiple sites)	0.318	0.681	0.000
C95 Leukaemia of unspecified cell type	0.318	0.682	0.000
E56 Other vitamin deficiencies	0.316	0.684	0.000
B35-B49 Mycoses	0.316	0.684	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.316	0.684	0.000
B35 Dermatophytosis	0.314	0.686	0.000
C93 Monocytic leukaemia	0.311	0.688	0.000
Q61 Cystic kidney disease	0.312	0.688	0.000
E34.3 Short stature, not elsewhere classified	0.311	0.689	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.689	0.311
Q43 Other congenital malformations of intestine	0.311	0.689	0.000
C71 Malignant neoplasm of brain	0.311	0.689	0.000
D64 Other anaemias	0.311	0.689	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.310	0.690	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.310	0.690	0.000
D69 Purpura and other haemorrhagic conditions	0.309	0.691	0.000
M40 Kyphosis and lordosis	0.307	0.693	0.000
M12.3 Palindromic rheumatism	0.306	0.694	0.000
E34.5 Androgen resistance syndrome	0.305	0.695	0.000
E34.4 Constitutional tall stature	0.305	0.695	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.305	0.695	0.000
E34.1 Other hypersecretion of intestinal hormones	0.305	0.695	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.305	0.695	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.305	0.695	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.305	0.695	0.000
C84.3 Lymphoepithelioid lymphoma	0.305	0.695	0.000
C84.2 T-zone lymphoma	0.305	0.695	0.000
C84.1 Sezary's diease	0.305	0.695	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.304	0.695	0.000
M32.8 Other forms of systemic lupus erythematosus	0.304	0.695	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.304	0.696	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.304	0.696	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.304	0.696	0.000
M09.0 Juvenile arthritis in psoriasis	0.304	0.696	0.000
M10.90 Gout, unspecified (Multiple sites)	0.303	0.697	0.000
M05.8 Other seropositive rheumatoid arthritis	0.303	0.697	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.302	0.698	0.000
E65-E68 Obesity and other hyperalimentation	0.300	0.699	0.000
M49 Spondylopathies in diseases classified elsewhere	0.300	0.700	0.000
B35.1 Tinea unguium	0.300	0.700	0.000
Q39 Congenital malformations of oesophagus	0.299	0.701	0.000
D69.6 Thrombocytopenia, unspecified	0.298	0.702	0.000
C15-C26 Malignant neoplasms of digestive organs	0.297	0.703	0.000
M00-M03 Infectious arthropathies	0.297	0.703	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.297	0.703	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.294	0.706	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.294	0.706	0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.294	0.706	0.000
M10.06 Idiopathic gout (Lower leg)	0.293	0.707	0.000
C84.4 Peripheral T-cell lymphoma	0.293	0.707	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.293	0.707	0.000
E34.8 Other specified endocrine disorders	0.290	0.709	0.000
C18 Malignant neoplasm of colon	0.290	0.710	0.000
D62 Acute posthaemorrhagic anaemia	0.290	0.710	0.000
E04.1 Non-toxic single thyroid nodule	0.289	0.711	0.000
C02.9 Tongue, unspecified	0.289	0.711	0.000
C02.1 Border of tongue	0.288	0.712	0.000
D64.9 Anaemia, unspecified	0.288	0.712	0.000
M08.98 Juvenile arthritis, unspecified (Other)	0.288	0.712	0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)	0.288	0.712	0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)	0.288	0.712	0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)	0.288	0.712	0.000
M08.94 Juvenile arthritis, unspecified (Hand)	0.288	0.712	0.000
M08.93 Juvenile arthritis, unspecified (Forearm)	0.288	0.712	0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)	0.288	0.712	0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)	0.288	0.712	0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)	0.288	0.712	0.000
C16 Malignant neoplasm of stomach	0.288	0.712	0.000
M10.04 Idiopathic gout (Hand)	0.287	0.712	0.000
M33 Dermatopolymyositis	0.287	0.713	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.286	0.713	0.000
C71.9 Brain, unspecified	0.287	0.713	0.000
C07 Malignant neoplasm of parotid gland	0.286	0.714	0.000
C04 Malignant neoplasm of floor of mouth	0.286	0.714	0.000
A00-A09 Intestinal infectious diseases	0.285	0.715	0.000
M10.96 Gout, unspecified (Lower leg)	0.284	0.716	0.000
C18.9 Colon, unspecified	0.284	0.716	0.000
C69 Malignant neoplasm of eye and adnexa	0.284	0.716	0.000
M07 Psoriatic and enteropathic arthropathies	0.283	0.717	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.283	0.717	0.000
M05.2 Rheumatoid vasculitis	0.283	0.717	0.000
M05.0 Felty's syndrome	0.283	0.717	0.000
K90-K93 Other diseases of the digestive system	0.282	0.718	0.000
M10.08 Idiopathic gout (Other)	0.281	0.718	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.281	0.718	0.000
M10.03 Idiopathic gout (Forearm)	0.281	0.718	0.000
M10.02 Idiopathic gout (Upper arm)	0.281	0.718	0.000
M10.01 Idiopathic gout (Shoulder region)	0.281	0.718	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.281	0.719	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.281	0.719	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.281	0.719	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.281	0.719	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.281	0.719	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.281	0.719	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.281	0.719	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations