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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2735042
log Bayes Factor = 68.7484
Chromosome 6   position 29,747,373  (GRCh37) Explore rs2735042 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
K51 Ulcerative colitis
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
0.000 0.000 1.000
R31 Unspecified haematuria
0.000 0.001 0.999
L40 Psoriasis
0.993 0.007 0.000
L40.5 Arthropathic psoriasis
0.985 0.015 0.000
K51.8 Other ulcerative colitis
0.000 0.023 0.977
K51.2 Ulcerative (chronic) proctitis
0.000 0.025 0.975
E83.1 Disorders of iron metabolism
0.000 0.025 0.975
K50-K52 Noninfective enteritis and colitis
0.000 0.060 0.940
K50 Crohn's disease [regional enteritis]
0.000 0.062 0.938
K51.4 Pseudopolyposis of colon
0.000 0.076 0.924
K50.9 Crohn's disease, unspecified
0.000 0.078 0.922
L40.0 Psoriasis vulgaris
0.918 0.082 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.091 0.909
K51.5 Mucosal proctocolitis
0.000 0.116 0.884
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.125 0.875
K50.1 Crohn's disease of large intestine
0.000 0.134 0.866
K50.8 Other Crohn's disease
0.000 0.169 0.831
L40.3 Pustulosis palmaris et plantaris
0.768 0.232 0.000
L40.1 Generalised pustular psoriasis
0.754 0.246 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.251 0.749
L40.2 Acrodermatitis continua
0.712 0.288 0.000
K90 Intestinal malabsorption
0.685 0.315 0.000
L40.4 Guttate psoriasis
0.672 0.327 0.000
L40.8 Other psoriasis
0.654 0.346 0.000
K90.8 Other intestinal malabsorption
0.554 0.446 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.544 0.456 0.000
K90.9 Intestinal malabsorption, unspecified
0.542 0.458 0.000
E10 Insulin-dependent diabetes mellitus
0.539 0.461 0.000
E10.3 With ophthalmic complications
0.539 0.461 0.000
E10.9 Without complications
0.529 0.471 0.000
K50.0 Crohn's disease of small intestine
0.000 0.477 0.523
E10.2 With renal complications
0.513 0.487 0.000
K90.3 Pancreatic steatorrhoea
0.491 0.509 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.491 0.509 0.000
K90.1 Tropical sprue
0.491 0.509 0.000
E10-E14 Diabetes mellitus
0.488 0.512 0.000
N13 Obstructive and reflux uropathy
0.477 0.523 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.474 0.526 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.451 0.549 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.443 0.557 0.000
N13.6 Pyonephrosis
0.439 0.561 0.000
E14 Unspecified diabetes mellitus
0.424 0.576 0.000
N10-N16 Renal tubulo-interstitial diseases
0.419 0.581 0.000
N11 Chronic tubulo-interstitial nephritis
0.417 0.583 0.000
E10.1 With ketoacidosis
0.410 0.590 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.404 0.596 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.403 0.597 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.401 0.599 0.000
N13.4 Hydroureter
0.400 0.600 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.400 0.600 0.000
E05.9 Thyrotoxicosis, unspecified
0.390 0.610 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.386 0.614 0.000
E10.4 With neurological complications
0.377 0.623 0.000
E13 Other specified diabetes mellitus
0.376 0.623 0.000
E10.7 With multiple complications
0.375 0.624 0.000
E11 Non-insulin-dependent diabetes mellitus
0.373 0.627 0.000
E14.9 Without complications
0.372 0.628 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.370 0.630 0.000
E14.5 With peripheral circulatory complications
0.364 0.636 0.000
E10.8 With unspecified complications
0.364 0.636 0.000
E00-E07 Disorders of thyroid gland
0.363 0.637 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.358 0.642 0.000
N11.1 Chronic obstructive pyelonephritis
0.357 0.643 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.355 0.645 0.000
E14.1 With ketoacidosis
0.353 0.647 0.000
E12 Malnutrition-related diabetes mellitus
0.350 0.650 0.000
E50-E64 Other nutritional deficiencies
0.340 0.660 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.337 0.663 0.000
E10.6 With other specified complications
0.333 0.667 0.000
E11.2 With renal complications
0.333 0.667 0.000
E05.8 Other thyrotoxicosis
0.323 0.677 0.000
E55 Vitamin D deficiency
0.321 0.679 0.000
E11.6 With other specified complications
0.320 0.680 0.000
E11.7 With multiple complications
0.317 0.683 0.000
E13.3 With ophthalmic complications
0.317 0.683 0.000
E10.0 With coma
0.313 0.687 0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.309 0.690 0.000
E55.9 Vitamin D deficiency, unspecified
0.308 0.692 0.000
E14.7 With multiple complications
0.304 0.696 0.000
E14.0 With coma
0.304 0.696 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.300 0.699 0.000
E20-E35 Disorders of other endocrine glands
0.300 0.700 0.000
N11.8 Other chronic tubulo-interstitial nephritis
0.299 0.701 0.000
E14.4 With neurological complications
0.297 0.703 0.000
E23 Hypofunction and other disorders of pituitary gland
0.293 0.707 0.000
E14.2 Withrenal complications
0.293 0.707 0.000
E05.5 Thyroid crisis or storm
0.289 0.711 0.000
E05.4 Thyrotoxicosis factitia
0.289 0.711 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.289 0.711 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.289 0.711 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.288 0.712 0.000
N15 Other renal tubulo-interstitial diseases
0.282 0.718 0.000
E14.8 With unspecified complications
0.278 0.722 0.000
E11.9 Without complications
0.277 0.723 0.000
E13.8 With unspecified complications
0.270 0.730 0.000
E13.7 With multiple complications
0.270 0.730 0.000
E13.6 With other specified complications
0.270 0.730 0.000
E13.5 With peripheral circulatory complications
0.270 0.730 0.000
E13.4 With neurological complications
0.270 0.730 0.000
E13.2 With renal complications
0.270 0.730 0.000
E13.1 With ketoacidosis
0.270 0.730 0.000
E13.0 With coma
0.270 0.730 0.000
E11.5 With peripheral circulatory complications
0.270 0.730 0.000
E23.2 Diabetes insipidus
0.269 0.731 0.000
E14.6 With other specified complications
0.264 0.736 0.000
E61 Deficiency of other nutrient elements
0.264 0.736 0.000
E11.1 With ketoacidosis
0.263 0.736 0.000
E11.0 With coma
0.263 0.737 0.000
N10 Acute tubulo-interstitial nephritis
0.261 0.739 0.000
E11.8 With unspecified complications
0.260 0.739 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.260 0.740 0.000
E00 Congenital iodine-deficiency syndrome
0.260 0.740 0.000
E23.0 Hypopituitarism
0.260 0.740 0.000
E10.5 With peripheral circulatory complications
0.258 0.742 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.255 0.745 0.000
N14.4 Toxic nephropathy, not elsewhere classified
0.255 0.745 0.000
N14.3 Nephropathy induced by heavy metals
0.255 0.745 0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
0.255 0.745 0.000
N14.0 Analgesic nephropathy
0.255 0.745 0.000
E12.9 Without complications
0.251 0.749 0.000
E12.8 With unspecified complications
0.251 0.749 0.000
E12.7 With multiple complications
0.251 0.749 0.000
E12.6 With other specified complications
0.251 0.749 0.000
E12.5 With peripheral circulatory complications
0.251 0.749 0.000
E12.4 With neurological complications
0.251 0.749 0.000
E12.3 With ophthalmic complications
0.251 0.749 0.000
E12.2 With renal complications
0.251 0.749 0.000
E12.1 With ketoacidosis
0.251 0.749 0.000
E12.0 With coma
0.251 0.749 0.000
E51 Thiamine deficiency
0.250 0.749 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.246 0.753 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.245 0.755 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.244 0.756 0.000
E63 Other nutritional deficiencies
0.244 0.756 0.000
E56 Other vitamin deficiencies
0.244 0.756 0.000
E50 Vitamin A deficiency
0.244 0.756 0.000
E60 Dietary zinc deficiency
0.244 0.756 0.000
E59 Dietary selenium deficiency
0.244 0.756 0.000
E54 Ascorbic acid deficiency
0.244 0.756 0.000
E52 Niacin deficiency [pellagra]
0.244 0.756 0.000
E58 Dietary calcium deficiency
0.241 0.758 0.000
E13.9 Without complications
0.233 0.766 0.000
E23.7 Disorder of pituitary gland, unspecified
0.233 0.767 0.000
E55.0 Rickets, active
0.230 0.770 0.000
E14.3 With ophthalmic complications
0.229 0.771 0.000
E23.6 Other disorders of pituitary gland
0.223 0.776 0.000
E28 Ovarian dysfunction
0.223 0.777 0.000
E31 Polyglandular dysfunction
0.222 0.778 0.000
E40-E46 Malnutrition
0.222 0.778 0.000
E07 Other disorders of thyroid
0.222 0.778 0.000
E21.0 Primary hyperparathyroidism
0.220 0.780 0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere
0.215 0.784 0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection
0.215 0.784 0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders
0.215 0.784 0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases
0.215 0.784 0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
0.215 0.784 0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases
0.215 0.784 0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
0.215 0.784 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.215 0.785 0.000
E32 Diseases of thymus
0.215 0.785 0.000
E30 Disorders of puberty, not elsewhere classified
0.215 0.785 0.000
E20 Hypoparathyroidism
0.214 0.786 0.000
E25 Adrenogenital disorders
0.212 0.787 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.210 0.790 0.000
E23.1 Drug-induced hypopituitarism
0.210 0.790 0.000
E24 Cushing's syndrome
0.208 0.792 0.000
E27 Other disorders of adrenal gland
0.207 0.793 0.000
N15.8 Other specified renal tubulo-interstitial diseases
0.202 0.798 0.000
N15.0 Balkan nephropathy
0.202 0.798 0.000
E61.2 Magnesium deficiency
0.200 0.800 0.000
E61.1 Iron deficiency
0.200 0.800 0.000
E53 Deficiency of other B group vitamins
0.196 0.804 0.000
N15.9 Renal tubulo-interstitial disease, unspecified
0.196 0.804 0.000
L40-L45 Papulosquamous disorders
0.192 0.808 0.000
E27.1 Primary adrenocortical insufficiency
0.192 0.808 0.000
N15.1 Renal and perinephric abscess
0.191 0.809 0.000
E61.9 Deficiency of nutrient element, unspecified
0.189 0.810 0.000
E61.8 Deficiency of other specified nutrient elements
0.189 0.810 0.000
E61.7 Deficiency of multiple nutrient elements
0.189 0.810 0.000
E61.6 Vanadium deficiency
0.189 0.810 0.000
E61.5 Molybdenum deficiency
0.189 0.810 0.000
E61.4 Chromium deficiency
0.189 0.810 0.000
E61.3 Manganese deficiency
0.189 0.810 0.000
E61.0 Copper deficiency
0.189 0.810 0.000
E28.3 Primary ovarian failure
0.189 0.811 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.187 0.813 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.187 0.813 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.187 0.813 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.187 0.813 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.187 0.813 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.187 0.813 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.187 0.813 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.187 0.813 0.000
E51.2 Wernicke's encephalopathy
0.186 0.813 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.815 0.185
E21.3 Hyperparathyroidism, unspecified
0.185 0.815 0.000
E15 Nondiabetic hypoglycaemic coma
0.183 0.817 0.000
E26 Hyperaldosteronism
0.180 0.820 0.000
E51.9 Thiamine deficiency, unspecified
0.180 0.820 0.000
E51.8 Other manifestations of thiamine deficiency
0.180 0.820 0.000
E51.1 Beriberi
0.180 0.820 0.000
E21.4 Other specified disorders of parathyroid gland
0.177 0.823 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.824 0.176
E50.9 Vitamin A deficiency, unspecified
0.175 0.825 0.000
E50.8 Other manifestations of vitamin A deficiency
0.175 0.825 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.175 0.825 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.175 0.825 0.000
E50.5 Vitamin A deficiency with night blindness
0.175 0.825 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.175 0.825 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.175 0.825 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.175 0.825 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.175 0.825 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.175 0.825 0.000
E56.9 Vitamin deficiency, unspecified
0.175 0.825 0.000
E56.8 Deficiency of other vitamins
0.175 0.825 0.000
E56.1 Deficiency of vitamin K
0.175 0.825 0.000
E56.0 Deficiency of vitamin E
0.175 0.825 0.000
E63.9 Nutritional deficiency, unspecified
0.175 0.825 0.000
E63.8 Other specified nutritional deficiencies
0.175 0.825 0.000
E63.1 Imbalance of constituents of food intake
0.175 0.825 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.175 0.825 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.175 0.825 0.000
E64.8 Sequelae of other nutritional deficiencies
0.175 0.825 0.000
E64.3 Sequelae of rickets
0.175 0.825 0.000
E64.2 Sequelae of vitamin C deficiency
0.175 0.825 0.000
E64.1 Sequelae of vitamin A deficiency
0.175 0.825 0.000
E64.0 Sequelae of protein-energy malnutrition
0.175 0.825 0.000
E24.0 Pituitary-dependent Cushing's disease
0.174 0.826 0.000
E21.2 Other hyperparathyroidism
0.174 0.826 0.000
E16 Other disorders of pancreatic internal secretion
0.172 0.828 0.000
E07.8 Other specified disorders of thyroid
0.172 0.828 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.833 0.167
E31.0 Autoimmune polyglandular failure
0.166 0.833 0.000
E06 Thyroiditis
0.164 0.836 0.001
E03 Other hypothyroidism
0.163 0.837 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.161 0.839 0.000
E29 Testicular dysfunction
0.161 0.839 0.000
E28.9 Ovarian dysfunction, unspecified
0.160 0.840 0.000
E28.8 Other ovarian dysfunction
0.160 0.840 0.000
E28.1 Androgen excess
0.160 0.840 0.000
E28.0 Oestrogen excess
0.160 0.840 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.160 0.840 0.000
N13.8 Other obstructive and reflux uropathy
0.160 0.840 0.000
E31.9 Polyglandular dysfunction, unspecified
0.159 0.840 0.000
E31.8 Other polyglandular dysfunction
0.159 0.840 0.000
E31.1 Polyglandular hyperfunction
0.159 0.840 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.159 0.840 0.000
E45 Retarded development following protein-energy malnutrition
0.159 0.840 0.000
E43 Unspecified severe protein-energy malnutrition
0.159 0.840 0.000
E42 Marasmic kwashiorkor
0.159 0.840 0.000
E41 Nutritional marasmus
0.159 0.840 0.000
E40 Kwashiorkor
0.159 0.840 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.159 0.840 0.000
E07.1 Dyshormogenetic goitre
0.159 0.841 0.000
E07.0 Hypersecretion of calcitonin
0.159 0.841 0.000
E30.9 Disorder of puberty, unspecified
0.154 0.845 0.000
E30.8 Other disorders of puberty
0.154 0.845 0.000
E30.1 Precocious puberty
0.154 0.845 0.000
E30.0 Delayed puberty
0.154 0.845 0.000
E32.9 Disease of thymus, unspecified
0.154 0.845 0.000
E32.8 Other diseases of thymus
0.154 0.845 0.000
E32.1 Abscess of thymus
0.154 0.845 0.000
E32.0 Persistent hyperplasia of thymus
0.154 0.845 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.154 0.845 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.154 0.845 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.154 0.845 0.000
E20.8 Other hypoparathyroidism
0.153 0.847 0.000
E20.1 Pseudohypoparathyroidism
0.153 0.847 0.000
E20.0 Idiopathic hypoparathyroidism
0.153 0.847 0.000
E25.9 Adrenogenital disorder, unspecified
0.152 0.847 0.000
E25.8 Other adrenogenital disorders
0.152 0.847 0.000
M06 Other rheumatoid arthritis
0.000 0.848 0.151
E20.9 Hypoparathyroidism, unspecified
0.151 0.848 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.848 0.152
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.150 0.850 0.000
E24.8 Other Cushing's syndrome
0.149 0.850 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.149 0.850 0.000
E24.3 Ectopic ACTH syndrome
0.149 0.850 0.000
E24.1 Nelson's syndrome
0.149 0.850 0.000
E27.5 Adrenomedullary hyperfunction
0.149 0.851 0.000
E27.0 Other adrenocortical overactivity
0.149 0.851 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.853 0.147
M06.0 Seronegative rheumatoid arthritis
0.000 0.853 0.147
E27.4 Other and unspecified adrenocortical insufficiency
0.145 0.855 0.000
E24.2 Drug-induced Cushing's syndrome
0.144 0.856 0.000
E16.1 Other hypoglycaemia
0.143 0.857 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.142 0.857 0.000
E53.1 Pyridoxine deficiency
0.141 0.859 0.000
E53.0 Riboflavin deficiency
0.141 0.859 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.859 0.140
L44 Other papulosquamous disorders
0.138 0.862 0.000
L41 Parapsoriasis
0.138 0.862 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.138 0.862 0.000
E34 Other endocrine disorders
0.137 0.863 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.866 0.134
E22 Hyperfunction of pituitary gland
0.133 0.867 0.000
E26.9 Hyperaldosteronism, unspecified
0.132 0.868 0.000
E26.8 Other hyperaldosteronism
0.129 0.870 0.000
E26.1 Secondary hyperaldosteronism
0.129 0.870 0.000
E53.8 Deficiency of other specified B group vitamins
0.129 0.871 0.000
E06.9 Thyroiditis, unspecified
0.126 0.873 0.000
E27.2 Addisonian crisis
0.126 0.874 0.000
E28.2 Polycystic ovarian syndrome
0.124 0.876 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.124 0.876 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.124 0.876 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.124 0.876 0.000
E16.4 Abnormal secretion of gastrin
0.124 0.876 0.000
E16.3 Increased secretion of glucagon
0.124 0.876 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.876 0.124
E03.1 Congenital hypothyroidism without goitre
0.123 0.877 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.878 0.122
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.878 0.122
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.121 0.879 0.000
E06.4 Drug-induced thyroiditis
0.118 0.882 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.118 0.882 0.001
E06.1 Subacute thyroiditis
0.118 0.882 0.001
E06.0 Acute thyroiditis
0.118 0.882 0.001
E03.5 Myxoedema coma
0.117 0.883 0.000
E03.4 Atrophy of thyroid (acquired)
0.117 0.883 0.000
E03.3 Postinfectious hypothyroidism
0.117 0.883 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.883 0.117
E46 Unspecified protein-energy malnutrition
0.116 0.884 0.000
L42 Pityriasis rosea
0.116 0.884 0.000
E29.9 Testicular dysfunction, unspecified
0.115 0.884 0.000
E29.8 Other testicular dysfunction
0.115 0.884 0.000
E29.0 Testicular hyperfunction
0.115 0.884 0.000
E44.1 Mild protein-energy malnutrition
0.114 0.885 0.000
E44.0 Moderate protein-energy malnutrition
0.114 0.885 0.000
E03.8 Other specified hypothyroidism
0.115 0.885 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.114 0.886 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.887 0.113
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.887 0.112
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.112 0.888 0.000
E53.9 Vitamin B deficiency, unspecified
0.111 0.889 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.891 0.109
M06.2 Rheumatoid bursitis
0.000 0.891 0.109
M06.1 Adult-onset Still's disease
0.000 0.891 0.109
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.894 0.105
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.894 0.105
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.894 0.105
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.894 0.105
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.894 0.105
E27.9 Disorder of adrenal gland, unspecified
0.104 0.896 0.000
E24.9 Cushing's syndrome, unspecified
0.103 0.896 0.000
E06.5 Other chronic thyroiditis
0.103 0.896 0.001
M06.3 Rheumatoid nodule
0.000 0.897 0.103
L41.9 Parapsoriasis, unspecified
0.099 0.901 0.000
L41.8 Other parapsoriasis
0.099 0.901 0.000
L41.5 Retiform parapsoriasis
0.099 0.901 0.000
L41.4 Large plaque parapsoriasis
0.099 0.901 0.000
L41.3 Small plaque parapsoriasis
0.099 0.901 0.000
L41.2 Lymphomatoid papulosis
0.099 0.901 0.000
L41.1 Pityriasis lichenoides chronica
0.099 0.901 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.099 0.901 0.000
L44.9 Papulosquamous disorder, unspecified
0.099 0.901 0.000
L44.8 Other specified papulosquamous disorders
0.099 0.901 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.099 0.901 0.000
L44.3 Lichen ruber moniliformis
0.099 0.901 0.000
L44.2 Lichen striatus
0.099 0.901 0.000
L44.1 Lichen nitidus
0.099 0.901 0.000
L44.0 Pityriasis rubra pilaris
0.099 0.901 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.099 0.901 0.000
E34.5 Androgen resistance syndrome
0.098 0.901 0.000
E34.4 Constitutional tall stature
0.098 0.901 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.098 0.901 0.000
E34.1 Other hypersecretion of intestinal hormones
0.098 0.901 0.000
E34.3 Short stature, not elsewhere classified
0.098 0.902 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.903 0.097
E22.9 Hyperfunction of pituitary gland, unspecified
0.096 0.904 0.000
E22.8 Other hyperfunction of pituitary gland
0.096 0.904 0.000
E07.9 Disorder of thyroid, unspecified
0.095 0.905 0.000
E65-E68 Obesity and other hyperalimentation
0.093 0.907 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.908 0.092
E27.8 Other specified disorders of adrenal gland
0.092 0.908 0.000
E34.8 Other specified endocrine disorders
0.091 0.909 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.091 0.909 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.090 0.910 0.000
E26.0 Primary hyperaldosteronism
0.089 0.911 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.915 0.085
C85.1 B-cell lymphoma, unspecified
0.085 0.915 0.000
E11.4 With neurological complications
0.085 0.915 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.916 0.083
K52 Other non-infective gastro-enteritis and colitis
0.000 0.918 0.082
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.918 0.082
E34.0 Carcinoid syndrome
0.080 0.920 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.920 0.080
C85.0 Lymphosarcoma
0.080 0.920 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.080 0.920 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.922 0.078
M06.18 Adult-onset Still's disease (Other)
0.000 0.922 0.078
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.922 0.078
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.922 0.078
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.922 0.078
M06.14 Adult-onset Still's disease (Hand)
0.000 0.922 0.078
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.922 0.078
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.922 0.078
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.922 0.078
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.922 0.078
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.922 0.078
M06.28 Rheumatoid bursitis (Other)
0.000 0.922 0.078
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.922 0.078
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.922 0.078
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.922 0.078
M06.24 Rheumatoid bursitis (Hand)
0.000 0.922 0.078
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.922 0.078
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.922 0.078
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.922 0.078
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.922 0.078
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.922 0.078
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.922 0.078
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.922 0.078
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.922 0.078
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.922 0.078
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.922 0.078
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.922 0.078
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.922 0.078
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.922 0.078
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.922 0.078
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.924 0.076
M05 Seropositive rheumatoid arthritis
0.001 0.925 0.075
E83 Disorders of mineral metabolism
0.001 0.925 0.074
R30-R39 Symptoms and signs involving the urinary system
0.000 0.925 0.075
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.925 0.075
L43 Lichen planus
0.075 0.925 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.926 0.074
M06.38 Rheumatoid nodule (Other)
0.000 0.926 0.074
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.926 0.074
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.926 0.074
M06.33 Rheumatoid nodule (Forearm)
0.000 0.926 0.074
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.926 0.074
E16.2 Hypoglycaemia, unspecified
0.074 0.926 0.000
K62.8 Other specified diseases of anus and rectum
0.000 0.926 0.074
E22.1 Hyperprolactinaemia
0.073 0.926 0.000
E34.9 Endocrine disorder, unspecified
0.071 0.928 0.000
E11.3 With ophthalmic complications
0.071 0.929 0.000
M05-M14 Inflammatory polyarthropathies
0.001 0.929 0.070
R39 Other symptoms and signs involving the urinary system
0.000 0.932 0.068
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.932 0.068
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.933 0.067
E67 Other hyperalimentation
0.067 0.933 0.000
E68 Sequelae of hyperalimentation
0.067 0.933 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.933 0.066
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.933 0.066
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.933 0.066
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.933 0.066
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.933 0.066
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.933 0.066
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.933 0.066
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.934 0.066
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.937 0.062
E29.1 Testicular hypofunction
0.060 0.939 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.940 0.060
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.940 0.060
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.940 0.060
R30 Pain associated with micturition
0.000 0.940 0.060
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.940 0.060
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.941 0.059
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.941 0.059
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.941 0.059
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.941 0.059
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.944 0.056
K90-K93 Other diseases of the digestive system
0.056 0.944 0.000
N13.3 Other and unspecified hydronephrosis
0.055 0.945 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.946 0.054
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.946 0.054
M05.2 Rheumatoid vasculitis
0.001 0.946 0.054
M05.1 Rheumatoid lung disease
0.001 0.946 0.054
M05.0 Felty's syndrome
0.001 0.946 0.054
E83.8 Other disorders of mineral metabolism
0.001 0.946 0.053
E83.2 Disorders of zinc metabolism
0.001 0.946 0.053
E83.0 Disorders of copper metabolism
0.001 0.946 0.053
L43.3 Subacute (active) lichen planus
0.054 0.946 0.000
L43.2 Lichenoid drug reaction
0.054 0.946 0.000
L43.1 Bullous lichen planus
0.054 0.946 0.000
L43.0 Hypertrophic lichen planus
0.054 0.946 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.946 0.053
R30.0 Dysuria
0.000 0.946 0.054
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.947 0.053
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.947 0.053
M14 Arthropathies in other diseases classified elsewhere
0.001 0.948 0.051
E22.0 Acromegaly and pituitary gigantism
0.051 0.948 0.001
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.949 0.050
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.949 0.050
M12 Other specific arthropathies
0.001 0.950 0.049
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.951 0.049
R39.2 Extrarenal uraemia
0.000 0.951 0.049
E67.8 Other specified hyperalimentation
0.048 0.952 0.000
E67.3 Hypervitaminosis D
0.048 0.952 0.000
E67.2 Megavitamin-B6 syndrome
0.048 0.952 0.000
E67.1 Hypercarotenaemia
0.048 0.952 0.000
E67.0 Hypervitaminosis A
0.048 0.952 0.000
K52.1 Toxic gastro-enteritis and colitis
0.000 0.953 0.047
E83.3 Disorders of phosphorus metabolism
0.001 0.953 0.046
R36 Urethral discharge
0.000 0.953 0.047
B02.9 Zoster without complication
0.047 0.953 0.000
M08 Juvenile arthritis
0.001 0.954 0.045
R30.1 Vesical tenesmus
0.000 0.954 0.046

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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