TreeWAS – Variant ID: rs2735052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.113	0.887
G37 Other demyelinating diseases of central nervous system	0.000	0.182	0.818
M06.9 Rheumatoid arthritis, unspecified	0.796	0.204	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.791	0.209	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.768	0.232	0.000
M06 Other rheumatoid arthritis	0.752	0.248	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.269	0.731
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.729	0.271	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.695	0.305	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.311	0.689
M06.0 Seronegative rheumatoid arthritis	0.686	0.314	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.644	0.356	0.000
M06.8 Other specified rheumatoid arthritis	0.643	0.357	0.000
G40-G47 Episodic and paroxysmal disorders	0.000	0.371	0.629
M06.3 Rheumatoid nodule	0.623	0.377	0.000
Chapter VI Diseases of the nervous system	0.000	0.377	0.623
G40 Epilepsy	0.000	0.379	0.621
G36 Other acute disseminated demyelination	0.000	0.394	0.606
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.604	0.396	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.593	0.407	0.000
G43 Migraine	0.000	0.410	0.590
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.589	0.411	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.413	0.587
G37.4 Subacute necrotising myelitis	0.000	0.413	0.587
G37.2 Central pontine myelinolysis	0.000	0.413	0.587
G37.1 Central demyelination of corpus callosum	0.000	0.413	0.587
G37.0 Diffuse sclerosis	0.000	0.413	0.587
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.414	0.586
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.415	0.585
G43.9 Migraine, unspecified	0.000	0.417	0.583
G30-G32 Other degenerative diseases of the nervous system	0.000	0.419	0.581
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.577	0.422	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.427	0.573
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.428	0.572
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.436	0.564
M06.34 Rheumatoid nodule (Hand)	0.562	0.438	0.000
G47 Sleep disorders	0.000	0.449	0.551
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.549	0.451	0.000
M05-M14 Inflammatory polyarthropathies	0.545	0.455	0.000
G47.9 Sleep disorder, unspecified	0.000	0.457	0.543
M05 Seropositive rheumatoid arthritis	0.541	0.459	0.000
M06.2 Rheumatoid bursitis	0.539	0.460	0.000
M06.1 Adult-onset Still's disease	0.539	0.460	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.538	0.462	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.463	0.537
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.530	0.470	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.528	0.472	0.000
G44 Other headache syndromes	0.000	0.482	0.518
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.516	0.484	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.511	0.489	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.507	0.493	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.500	0.500	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.499	0.501	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.502	0.498
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.503	0.497
G31.8 Other specified degenerative diseases of nervous system	0.000	0.507	0.493
M06.08 Seronegative rheumatoid arthritis (Other)	0.492	0.508	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.492	0.508	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.492	0.508	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.486	0.514	0.000
G40.9 Epilepsy, unspecified	0.000	0.520	0.480
G44.2 Tension-type headache	0.000	0.523	0.477
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.476	0.523	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.476	0.524	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.471	0.529	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.530	0.470
M06.33 Rheumatoid nodule (Forearm)	0.461	0.538	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.461	0.539	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.461	0.539	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.461	0.539	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.461	0.539	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.461	0.539	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.461	0.539	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.461	0.539	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.461	0.539	0.000
M12 Other specific arthropathies	0.454	0.546	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.548	0.452
G47.2 Disorders of the sleep-wake schedule	0.000	0.550	0.450
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.552	0.448
M06.39 Rheumatoid nodule (Site unspecified)	0.447	0.553	0.000
M06.38 Rheumatoid nodule (Other)	0.447	0.553	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.447	0.553	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.447	0.553	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.447	0.553	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.446	0.554	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.554	0.446
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.554	0.446
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.560	0.440
E05.9 Thyrotoxicosis, unspecified	0.000	0.562	0.438
G36.9 Acute disseminated demyelination, unspecified	0.000	0.565	0.435
G36.8 Other specified acute disseminated demyelination	0.000	0.565	0.435
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.565	0.435
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.569	0.431
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.431	0.569	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.570	0.430
M05.8 Other seropositive rheumatoid arthritis	0.427	0.573	0.000
G43.2 Status migrainosus	0.000	0.577	0.423
M06.4 Inflammatory polyarthropathy	0.422	0.578	0.000
G41 Status epilepticus	0.000	0.580	0.420
M35.0 Sicca syndrome [Sjogren]	0.000	0.580	0.420
G43.0 Migraine without aura [common migraine]	0.000	0.582	0.417
G44.3 Chronic posttraumatic headache	0.000	0.585	0.415
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.413	0.587	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.587	0.413
G36.0 Neuromyelitis optica [Devic]	0.000	0.595	0.405
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.595	0.404
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.599	0.401
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.401	0.599	0.000
E06 Thyroiditis	0.000	0.601	0.399
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.397	0.603	0.000
E00-E07 Disorders of thyroid gland	0.000	0.603	0.397
E06.3 Autoimmune thyroiditis	0.000	0.607	0.393
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.392	0.608	0.000
G81 Hemiplegia	0.000	0.609	0.391
M09 Juvenile arthritis in diseases classified elsewhere	0.390	0.609	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.389	0.610	0.000
G31.0 Circumscribed brain atrophy	0.000	0.610	0.389
G40.5 Special epileptic syndromes	0.000	0.610	0.389
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.388	0.612	0.000
M05.0 Felty's syndrome	0.388	0.612	0.000
M05.1 Rheumatoid lung disease	0.387	0.613	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.387	0.613	0.000
M06.18 Adult-onset Still's disease (Other)	0.387	0.613	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.387	0.613	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.387	0.613	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.387	0.613	0.000
M06.14 Adult-onset Still's disease (Hand)	0.387	0.613	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.387	0.613	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.387	0.613	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.387	0.613	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.387	0.613	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.387	0.613	0.000
M06.28 Rheumatoid bursitis (Other)	0.387	0.613	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.387	0.613	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.387	0.613	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.387	0.613	0.000
M06.24 Rheumatoid bursitis (Hand)	0.387	0.613	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.387	0.613	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.387	0.613	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.387	0.613	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.387	0.613	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.386	0.614	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.386	0.614	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.614	0.386
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.618	0.382
M06.30 Rheumatoid nodule (Multiple sites)	0.382	0.618	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.622	0.378
E83 Disorders of mineral metabolism	0.000	0.626	0.374
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.628	0.372
M06.32 Rheumatoid nodule (Upper arm)	0.371	0.628	0.000
E06.9 Thyroiditis, unspecified	0.000	0.629	0.371
M08 Juvenile arthritis	0.369	0.631	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.632	0.368
G44.8 Other specified headache syndromes	0.000	0.633	0.366
M05.2 Rheumatoid vasculitis	0.366	0.634	0.000
G46.7 Other lacunar syndromes	0.000	0.635	0.365
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.636	0.364
M11 Other crystal arthropathies	0.362	0.638	0.000
M12.2 Villonodular synovitis (pigmented)	0.361	0.639	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.640	0.360
M12.3 Palindromic rheumatism	0.358	0.642	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.644	0.356
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.646	0.354
G81.9 Hemiplegia, unspecified	0.000	0.647	0.353
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.346	0.654	0.000
G46.4 Cerebellar stroke syndrome	0.000	0.655	0.344
G43.3 Complicated migraine	0.000	0.656	0.343
G47.4 Narcolepsy and cataplexy	0.000	0.659	0.341
G03 Meningitis due to other and unspecified causes	0.000	0.661	0.339
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.663	0.337
G46.6 Pure sensory lacunar syndrome	0.000	0.663	0.337
G46.5 Pure motor lacunar syndrome	0.000	0.663	0.337
G46.2 Posterior cerebral artery syndrome	0.000	0.663	0.337
G46.1 Anterior cerebral artery syndrome	0.000	0.663	0.337
G46.0 Middle cerebral artery syndrome	0.000	0.663	0.337
M12.5 Traumatic arthropathy	0.336	0.664	0.000
G82 Paraplegia and tetraplegia	0.000	0.664	0.336
G00 Bacterial meningitis, not elsewhere classified	0.000	0.665	0.335
M14 Arthropathies in other diseases classified elsewhere	0.333	0.667	0.000
G44.0 Cluster headache syndrome	0.000	0.667	0.333
E83.5 Disorders of calcium metabolism	0.000	0.672	0.328
M12.8 Other specific arthropathies, not elsewhere classified	0.326	0.674	0.000
M12.4 Intermittent hydrarthrosis	0.326	0.674	0.000
M12.1 Kaschin-Beck disease	0.326	0.674	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.326	0.674	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.675	0.324
G70-G73 Diseases of myoneural junction and muscle	0.000	0.678	0.322
G46.3 Brain stem stroke syndrome	0.000	0.682	0.318
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.683	0.317
G44.1 Vascular headache, not elsewhere classified	0.000	0.684	0.316
E05.5 Thyroid crisis or storm	0.000	0.684	0.315
E05.4 Thyrotoxicosis factitia	0.000	0.684	0.315
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.684	0.315
E06.5 Other chronic thyroiditis	0.000	0.687	0.313
E03 Other hypothyroidism	0.000	0.688	0.312
G06.1 Intraspinal abscess and granuloma	0.000	0.689	0.311
G41.0 Grand mal status epilepticus	0.000	0.690	0.310
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.691	0.308
G06.2 Extradural and subdural abscess, unspecified	0.000	0.692	0.308
M13 Other arthritis	0.307	0.693	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.306	0.693	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.306	0.693	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.306	0.693	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.306	0.693	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.306	0.693	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.306	0.693	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.306	0.693	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.306	0.693	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.306	0.693	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.694	0.306
G40.8 Other epilepsy	0.000	0.695	0.304
G43.8 Other migraine	0.000	0.695	0.304
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.696	0.304
M06.48 Inflammatory polyarthropathy (Other)	0.302	0.697	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.302	0.697	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.302	0.697	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.302	0.697	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.302	0.697	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.302	0.697	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.302	0.697	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.302	0.697	0.000
G41.8 Other status epilepticus	0.000	0.698	0.301
G41.2 Complex partial status epilepticus	0.000	0.698	0.301
G41.1 Petit mal status epilepticus	0.000	0.698	0.301
G90-G99 Other disorders of the nervous system	0.000	0.698	0.302
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.699	0.300
E05.8 Other thyrotoxicosis	0.000	0.704	0.296
M12.24 Villonodular synovitis (pigmented) (Hand)	0.293	0.707	0.000
G47.8 Other sleep disorders	0.000	0.708	0.291
G45.3 Amaurosis fugax	0.000	0.712	0.288
E06.4 Drug-induced thyroiditis	0.000	0.714	0.286
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.714	0.286
E06.0 Acute thyroiditis	0.000	0.714	0.286
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.715	0.285
E00 Congenital iodine-deficiency syndrome	0.000	0.715	0.285
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.717	0.283
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.281	0.718	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.719	0.281
G81.0 Flaccid hemiplegia	0.000	0.720	0.280
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.280	0.720	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.280	0.720	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.280	0.720	0.000
M09.0 Juvenile arthritis in psoriasis	0.280	0.720	0.000
M05.09 Felty's syndrome (Site unspecified)	0.278	0.722	0.000
M05.08 Felty's syndrome (Other)	0.278	0.722	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.278	0.722	0.000
M05.06 Felty's syndrome (Lower leg)	0.278	0.722	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.278	0.722	0.000
M05.04 Felty's syndrome (Hand)	0.278	0.722	0.000
M05.03 Felty's syndrome (Forearm)	0.278	0.722	0.000
M05.02 Felty's syndrome (Upper arm)	0.278	0.722	0.000
M05.01 Felty's syndrome (Shoulder region)	0.278	0.722	0.000
M05.00 Felty's syndrome (Multiple sites)	0.278	0.722	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.278	0.722	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.278	0.722	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.278	0.722	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.278	0.722	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.278	0.722	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.278	0.722	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.278	0.722	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.278	0.722	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.278	0.722	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.278	0.722	0.000
G82.1 Spastic paraplegia	0.000	0.722	0.278
M12.39 Palindromic rheumatism (Site unspecified)	0.278	0.722	0.000
M05.18 Rheumatoid lung disease (Other)	0.278	0.722	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.278	0.722	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.278	0.722	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.278	0.722	0.000
M05.14 Rheumatoid lung disease (Hand)	0.278	0.722	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.278	0.722	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.278	0.722	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.278	0.722	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.278	0.722	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.277	0.722	0.000
M13.8 Other specified arthritis	0.276	0.724	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.725	0.275
M11.9 Crystal arthropathy, unspecified	0.272	0.727	0.000
G81.1 Spastic hemiplegia	0.000	0.728	0.272
M12.30 Palindromic rheumatism (Multiple sites)	0.271	0.729	0.000
G80 Infantile cerebral palsy	0.000	0.730	0.270
E83.8 Other disorders of mineral metabolism	0.000	0.732	0.268
E83.2 Disorders of zinc metabolism	0.000	0.732	0.268
E83.0 Disorders of copper metabolism	0.000	0.732	0.268
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.732	0.268
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.733	0.267
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.733	0.267
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.733	0.267
M08.9 Juvenile arthritis, unspecified	0.265	0.735	0.000
M08.8 Other juvenile arthritis	0.265	0.735	0.000
M08.4 Pauciarticular juvenile arthritis	0.265	0.735	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.265	0.735	0.000
M08.2 Juvenile arthritis with systemic onset	0.265	0.735	0.000
M08.1 Juvenile ankylosing spondylitis	0.265	0.735	0.000
E07 Other disorders of thyroid	0.000	0.736	0.264
M05.29 Rheumatoid vasculitis (Site unspecified)	0.263	0.736	0.000
M11.8 Other specified crystal arthropathies	0.264	0.736	0.000
M05.28 Rheumatoid vasculitis (Other)	0.263	0.737	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.263	0.737	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.263	0.737	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.263	0.737	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.263	0.737	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.263	0.737	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.263	0.737	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.263	0.737	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.738	0.261
M11.1 Familial chondrocalcinosis	0.260	0.740	0.000
M11.0 Hydroxyapatite deposition disease	0.260	0.740	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.259	0.740	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.259	0.741	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.259	0.741	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.259	0.741	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.259	0.741	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.259	0.741	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.259	0.741	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.259	0.741	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.259	0.741	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.259	0.741	0.000
G41.9 Status epilepticus, unspecified	0.000	0.741	0.259
M12.38 Palindromic rheumatism (Other)	0.257	0.743	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.257	0.743	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.257	0.743	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.257	0.743	0.000
M12.34 Palindromic rheumatism (Hand)	0.257	0.743	0.000
M12.33 Palindromic rheumatism (Forearm)	0.257	0.743	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.257	0.743	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.257	0.743	0.000
G82.4 Spastic tetraplegia	0.000	0.743	0.257
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.746	0.254
G04.1 Tropical spastic paraplegia	0.000	0.746	0.254
G04.0 Acute disseminated encephalitis	0.000	0.746	0.254
G70 Myasthenia gravis and other myoneural disorders	0.000	0.748	0.252
M12.57 Traumatic arthropathy (Ankle and foot)	0.251	0.748	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.749	0.251
G82.5 Tetraplegia, unspecified	0.000	0.749	0.251
G00.1 Pneumococcal meningitis	0.000	0.750	0.250
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.751	0.248
K90 Intestinal malabsorption	0.000	0.752	0.248
E03.9 Hypothyroidism, unspecified	0.000	0.753	0.247
M08.0 Juvenile rheumatoid arthritis	0.243	0.756	0.000
G03.8 Meningitis due to other specified causes	0.000	0.756	0.243
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.756	0.243
G03.1 Chronic meningitis	0.000	0.756	0.243
G03.0 Nonpyogenic meningitis	0.000	0.756	0.243
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.757	0.243
M07 Psoriatic and enteropathic arthropathies	0.241	0.758	0.000
M12.59 Traumatic arthropathy (Site unspecified)	0.241	0.759	0.000
M12.58 Traumatic arthropathy (Other)	0.241	0.759	0.000
M12.56 Traumatic arthropathy (Lower leg)	0.241	0.759	0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.241	0.759	0.000
M12.54 Traumatic arthropathy (Hand)	0.241	0.759	0.000
M12.53 Traumatic arthropathy (Forearm)	0.241	0.759	0.000
M12.52 Traumatic arthropathy (Upper arm)	0.241	0.759	0.000
M12.51 Traumatic arthropathy (Shoulder region)	0.241	0.759	0.000
M12.50 Traumatic arthropathy (Multiple sites)	0.241	0.759	0.000
G82.3 Flaccid tetraplegia	0.000	0.759	0.241
G82.0 Flaccid paraplegia	0.000	0.759	0.241
M05.20 Rheumatoid vasculitis (Multiple sites)	0.240	0.759	0.000
G96 Other disorders of central nervous system	0.000	0.760	0.240
G00.8 Other bacterial meningitis	0.000	0.760	0.240
G00.3 Staphylococcal meningitis	0.000	0.760	0.240
G00.2 Streptococcal meningitis	0.000	0.760	0.240
G00.0 Haemophilus meningitis	0.000	0.760	0.240
E83.3 Disorders of phosphorus metabolism	0.000	0.760	0.240
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.239	0.761	0.000
M14.4 Arthropathy in amyloidosis	0.239	0.761	0.000
M14.3 Lipoid dermatoarthritis	0.239	0.761	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.239	0.761	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.239	0.761	0.000
E06.1 Subacute thyroiditis	0.000	0.761	0.239
G30 Alzheimer's disease	0.000	0.764	0.236
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.234	0.766	0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.234	0.766	0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.234	0.766	0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.234	0.766	0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.234	0.766	0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.234	0.766	0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.234	0.766	0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.234	0.766	0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.234	0.766	0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.234	0.766	0.000
M12.19 Kaschin-Beck disease (Site unspecified)	0.234	0.766	0.000
M12.18 Kaschin-Beck disease (Other)	0.234	0.766	0.000
M12.17 Kaschin-Beck disease (Ankle and foot)	0.234	0.766	0.000
M12.16 Kaschin-Beck disease (Lower leg)	0.234	0.766	0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.234	0.766	0.000
M12.14 Kaschin-Beck disease (Hand)	0.234	0.766	0.000
M12.13 Kaschin-Beck disease (Forearm)	0.234	0.766	0.000
M12.12 Kaschin-Beck disease (Upper arm)	0.234	0.766	0.000
M12.11 Kaschin-Beck disease (Shoulder region)	0.234	0.766	0.000
M12.10 Kaschin-Beck disease (Multiple sites)	0.234	0.766	0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.234	0.766	0.000
M12.48 Intermittent hydrarthrosis (Other)	0.234	0.766	0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.234	0.766	0.000
M12.46 Intermittent hydrarthrosis (Lower leg)	0.234	0.766	0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.234	0.766	0.000
M12.44 Intermittent hydrarthrosis (Hand)	0.234	0.766	0.000
M12.43 Intermittent hydrarthrosis (Forearm)	0.234	0.766	0.000
M12.42 Intermittent hydrarthrosis (Upper arm)	0.234	0.766	0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.234	0.766	0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.234	0.766	0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.234	0.766	0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.234	0.766	0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.234	0.766	0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.234	0.766	0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.234	0.766	0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.234	0.766	0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.234	0.766	0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.234	0.766	0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.234	0.766	0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.234	0.766	0.000
M13.89 Other specified arthritis (Site unspecified)	0.234	0.766	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.769	0.231
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.769	0.231
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.773	0.227
G03.9 Meningitis, unspecified	0.000	0.774	0.226
G83 Other paralytic syndromes	0.000	0.776	0.224
E03.5 Myxoedema coma	0.000	0.776	0.224
E03.4 Atrophy of thyroid (acquired)	0.000	0.776	0.224
E03.3 Postinfectious hypothyroidism	0.000	0.776	0.224
M10 Gout	0.223	0.777	0.000
M13.80 Other specified arthritis (Multiple sites)	0.222	0.778	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.220	0.780	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.780	0.219
G02.1 Meningitis in mycoses	0.000	0.780	0.219
G80.8 Other infantile cerebral palsy	0.000	0.781	0.219
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.782	0.218
M13.86 Other specified arthritis (Lower leg)	0.217	0.783	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.783	0.217
E07.8 Other specified disorders of thyroid	0.000	0.785	0.215
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.786	0.214
M14.2 Diabetic arthropathy	0.213	0.787	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.787	0.213
M11.2 Other chondrocalcinosis	0.208	0.792	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.208	0.792	0.000
E03.8 Other specified hypothyroidism	0.000	0.794	0.206
G00.9 Bacterial meningitis, unspecified	0.000	0.794	0.205
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.795	0.204
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.795	0.204
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.795	0.204
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.795	0.204
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.795	0.204
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.795	0.204
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.795	0.204
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.795	0.204
M13.1 Monoarthritis, not elsewhere classified	0.203	0.797	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.798	0.202
M09.09 Juvenile arthritis in psoriasis (Site unspecified)	0.201	0.799	0.000
M09.08 Juvenile arthritis in psoriasis (Other)	0.201	0.799	0.000
M09.07 Juvenile arthritis in psoriasis (Ankle and foot)	0.201	0.799	0.000
M09.06 Juvenile arthritis in psoriasis (Lower leg)	0.201	0.799	0.000
M09.05 Juvenile arthritis in psoriasis (Pelvic region and thigh)	0.201	0.799	0.000
M09.04 Juvenile arthritis in psoriasis (Hand)	0.201	0.799	0.000
M09.03 Juvenile arthritis in psoriasis (Forearm)	0.201	0.799	0.000
M09.02 Juvenile arthritis in psoriasis (Upper arm)	0.201	0.799	0.000
M09.01 Juvenile arthritis in psoriasis (Shoulder region)	0.201	0.799	0.000
M09.00 Juvenile arthritis in psoriasis (Multiple sites)	0.201	0.799	0.000
M09.19 Juvenile arthritis in Crohn's disease [regional enteritis] (Site unspecified)	0.201	0.799	0.000
M09.18 Juvenile arthritis in Crohn's disease [regional enteritis] (Other)	0.201	0.799	0.000
M09.17 Juvenile arthritis in Crohn's disease [regional enteritis] (Ankle and foot)	0.201	0.799	0.000
M09.16 Juvenile arthritis in Crohn's disease [regional enteritis] (Lower leg)	0.201	0.799	0.000
M09.15 Juvenile arthritis in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.201	0.799	0.000
M09.14 Juvenile arthritis in Crohn's disease [regional enteritis] (Hand)	0.201	0.799	0.000
M09.13 Juvenile arthritis in Crohn's disease [regional enteritis] (Forearm)	0.201	0.799	0.000
M09.12 Juvenile arthritis in Crohn's disease [regional enteritis] (Upper arm)	0.201	0.799	0.000
M09.11 Juvenile arthritis in Crohn's disease [regional enteritis] (Shoulder region)	0.201	0.799	0.000
M09.10 Juvenile arthritis in Crohn's disease [regional enteritis] (Multiple sites)	0.201	0.799	0.000
M09.29 Juvenile arthritis in ulcerative colitis (Site unspecified)	0.201	0.799	0.000
M09.28 Juvenile arthritis in ulcerative colitis (Other)	0.201	0.799	0.000
M09.27 Juvenile arthritis in ulcerative colitis (Ankle and foot)	0.201	0.799	0.000
M09.26 Juvenile arthritis in ulcerative colitis (Lower leg)	0.201	0.799	0.000
M09.25 Juvenile arthritis in ulcerative colitis (Pelvic region and thigh)	0.201	0.799	0.000
M09.24 Juvenile arthritis in ulcerative colitis (Hand)	0.201	0.799	0.000
M09.23 Juvenile arthritis in ulcerative colitis (Forearm)	0.201	0.799	0.000
M09.22 Juvenile arthritis in ulcerative colitis (Upper arm)	0.201	0.799	0.000
M09.21 Juvenile arthritis in ulcerative colitis (Shoulder region)	0.201	0.799	0.000
M09.20 Juvenile arthritis in ulcerative colitis (Multiple sites)	0.201	0.799	0.000
M09.89 Juvenile arthritis in other diseases classified elsewhere (Site unspecified)	0.201	0.799	0.000
M09.88 Juvenile arthritis in other diseases classified elsewhere (Other)	0.201	0.799	0.000
M09.87 Juvenile arthritis in other diseases classified elsewhere (Ankle and foot)	0.201	0.799	0.000
M09.86 Juvenile arthritis in other diseases classified elsewhere (Lower leg)	0.201	0.799	0.000
M09.85 Juvenile arthritis in other diseases classified elsewhere (Pelvic region and thigh)	0.201	0.799	0.000
M09.84 Juvenile arthritis in other diseases classified elsewhere (Hand)	0.201	0.799	0.000
M09.83 Juvenile arthritis in other diseases classified elsewhere (Forearm)	0.201	0.799	0.000
M09.82 Juvenile arthritis in other diseases classified elsewhere (Upper arm)	0.201	0.799	0.000
M09.81 Juvenile arthritis in other diseases classified elsewhere (Shoulder region)	0.201	0.799	0.000
M09.80 Juvenile arthritis in other diseases classified elsewhere (Multiple sites)	0.201	0.799	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.799	0.201
G80.9 Infantile cerebral palsy, unspecified	0.000	0.799	0.201
M35 Other systemic involvement of connective tissue	0.000	0.800	0.200
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.801	0.199
M13.88 Other specified arthritis (Other)	0.198	0.802	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.198	0.802	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.198	0.802	0.000
M13.84 Other specified arthritis (Hand)	0.198	0.802	0.000
M13.83 Other specified arthritis (Forearm)	0.198	0.802	0.000
M13.82 Other specified arthritis (Upper arm)	0.198	0.802	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations