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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2735057
log Bayes Factor = 21.2679
Chromosome 6   position 29,698,031  (GRCh37) Explore rs2735057 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.016 0.984
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.130 0.870
G37 Other demyelinating diseases of central nervous system
0.000 0.162 0.838
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.219 0.781
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.245 0.755
G36 Other acute disseminated demyelination
0.000 0.365 0.635
G37.5 Concentric sclerosis [Balo]
0.000 0.399 0.601
G37.4 Subacute necrotising myelitis
0.000 0.399 0.601
G37.2 Central pontine myelinolysis
0.000 0.399 0.601
G37.1 Central demyelination of corpus callosum
0.000 0.399 0.601
G37.0 Diffuse sclerosis
0.000 0.399 0.601
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.436 0.564
G36.0 Neuromyelitis optica [Devic]
0.000 0.534 0.466
G36.9 Acute disseminated demyelination, unspecified
0.000 0.545 0.455
G36.8 Other specified acute disseminated demyelination
0.000 0.545 0.455
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.545 0.455
K90 Intestinal malabsorption
0.000 0.752 0.248
K90.3 Pancreatic steatorrhoea
0.000 0.822 0.178
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.822 0.178
K90.1 Tropical sprue
0.000 0.822 0.178
M35.0 Sicca syndrome [Sjogren]
0.000 0.822 0.178
K90.8 Other intestinal malabsorption
0.000 0.826 0.173
K90.9 Intestinal malabsorption, unspecified
0.000 0.841 0.158
Chapter VI Diseases of the nervous system
0.000 0.862 0.138
G30-G32 Other degenerative diseases of the nervous system
0.000 0.873 0.127
G40-G47 Episodic and paroxysmal disorders
0.000 0.874 0.126
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.877 0.123
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.879 0.121
E83 Disorders of mineral metabolism
0.000 0.880 0.120
G40 Epilepsy
0.000 0.881 0.119
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.882 0.118
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.883 0.117
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.883 0.117
E05.9 Thyrotoxicosis, unspecified
0.000 0.885 0.115
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.887 0.113
G47.9 Sleep disorder, unspecified
0.000 0.890 0.110
G90-G99 Other disorders of the nervous system
0.000 0.891 0.109
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.891 0.109
G47 Sleep disorders
0.000 0.892 0.108
G43 Migraine
0.000 0.894 0.106
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.895 0.105
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.897 0.103
G99 Other disorders of nervous system in diseases classified elsewhere
0.000 0.897 0.103
G31.8 Other specified degenerative diseases of nervous system
0.000 0.897 0.103
G43.9 Migraine, unspecified
0.000 0.898 0.102
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.898 0.102
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.900 0.100
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.903 0.097
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.905 0.095
E06 Thyroiditis
0.000 0.906 0.094
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.907 0.093
E06.3 Autoimmune thyroiditis
0.000 0.907 0.093
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.908 0.092
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.908 0.092
G31.2 Degeneration of nervous system due to alcohol
0.000 0.908 0.091
G96 Other disorders of central nervous system
0.000 0.909 0.091
E00-E07 Disorders of thyroid gland
0.000 0.909 0.091
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.912 0.088
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.912 0.087
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.913 0.087
E06.9 Thyroiditis, unspecified
0.000 0.913 0.087
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.914 0.086
E83.8 Other disorders of mineral metabolism
0.000 0.914 0.086
E83.2 Disorders of zinc metabolism
0.000 0.914 0.086
E83.0 Disorders of copper metabolism
0.000 0.914 0.086
G47.2 Disorders of the sleep-wake schedule
0.000 0.914 0.086
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.914 0.086
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.915 0.085
E05.5 Thyroid crisis or storm
0.000 0.916 0.084
E05.4 Thyrotoxicosis factitia
0.000 0.916 0.084
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.916 0.084
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.916 0.084
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.916 0.084
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.918 0.082
G41 Status epilepticus
0.000 0.918 0.082
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.918 0.082
G96.1 Disorders of meninges, not elsewhere classified
0.000 0.919 0.081
G81 Hemiplegia
0.000 0.919 0.081
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.920 0.080
G31.0 Circumscribed brain atrophy
0.000 0.920 0.079
E83.5 Disorders of calcium metabolism
0.000 0.921 0.079
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.922 0.078
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.922 0.078
G43.0 Migraine without aura [common migraine]
0.000 0.923 0.076
G97.1 Other reaction to spinal and lumbar puncture
0.000 0.924 0.076
G43.2 Status migrainosus
0.000 0.924 0.076
G40.8 Other epilepsy
0.000 0.924 0.076
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.925 0.075
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.000 0.926 0.074
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.000 0.926 0.074
E83.3 Disorders of phosphorus metabolism
0.000 0.926 0.074
E05.8 Other thyrotoxicosis
0.000 0.927 0.073
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.927 0.073
G46.7 Other lacunar syndromes
0.000 0.927 0.073
G95 Other diseases of spinal cord
0.000 0.927 0.073
G00 Bacterial meningitis, not elsewhere classified
0.000 0.927 0.073
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.928 0.072
G70-G73 Diseases of myoneural junction and muscle
0.000 0.928 0.072
G47.4 Narcolepsy and cataplexy
0.000 0.928 0.072
E06.5 Other chronic thyroiditis
0.000 0.928 0.072
E03 Other hypothyroidism
0.000 0.928 0.072
G44 Other headache syndromes
0.000 0.929 0.071
G82 Paraplegia and tetraplegia
0.000 0.929 0.071
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.930 0.070
G03 Meningitis due to other and unspecified causes
0.000 0.930 0.070
G81.9 Hemiplegia, unspecified
0.000 0.930 0.070
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.930 0.069
G06.2 Extradural and subdural abscess, unspecified
0.000 0.931 0.069
G43.1 Migraine with aura [classical migraine]
0.000 0.931 0.068
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.932 0.068
E06.4 Drug-induced thyroiditis
0.000 0.932 0.067
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.932 0.067
E06.0 Acute thyroiditis
0.000 0.932 0.067
G06.1 Intraspinal abscess and granuloma
0.000 0.933 0.067
G40.9 Epilepsy, unspecified
0.000 0.933 0.067
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.000 0.933 0.067
G46.6 Pure sensory lacunar syndrome
0.000 0.933 0.067
G46.5 Pure motor lacunar syndrome
0.000 0.933 0.067
G46.2 Posterior cerebral artery syndrome
0.000 0.933 0.067
G46.1 Anterior cerebral artery syndrome
0.000 0.933 0.067
G46.0 Middle cerebral artery syndrome
0.000 0.933 0.067
G46.3 Brain stem stroke syndrome
0.000 0.933 0.066
G96.0 Cerebrospinal fluid leak
0.000 0.934 0.066
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.934 0.066
G96.9 Disorder of central nervous system, unspecified
0.000 0.934 0.066
G40.5 Special epileptic syndromes
0.000 0.934 0.066
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.934 0.065
E00 Congenital iodine-deficiency syndrome
0.000 0.934 0.065
G95.1 Vascular myelopathies
0.000 0.936 0.064
G97.9 Postprocedural disorder of nervous system, unspecified
0.000 0.937 0.063
G97.2 Intracranial hypotension following ventricular shunting
0.000 0.937 0.063
G92 Toxic encephalopathy
0.000 0.937 0.062
G80 Infantile cerebral palsy
0.000 0.938 0.062
G95.8 Other specified diseases of spinal cord
0.000 0.938 0.062
G46.4 Cerebellar stroke syndrome
0.000 0.938 0.062
G90 Disorders of autonomic nervous system
0.000 0.938 0.062
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.938 0.062
G30 Alzheimer's disease
0.000 0.939 0.061
G91 Hydrocephalus
0.000 0.939 0.061
E06.1 Subacute thyroiditis
0.000 0.939 0.060
G81.1 Spastic hemiplegia
0.000 0.940 0.060
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.940 0.060
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.940 0.060
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.940 0.060
G97.8 Other postprocedural disorders of nervous system
0.000 0.940 0.060
G43.3 Complicated migraine
0.000 0.940 0.059
G41.8 Other status epilepticus
0.000 0.941 0.059
G41.2 Complex partial status epilepticus
0.000 0.941 0.059
G41.1 Petit mal status epilepticus
0.000 0.941 0.059
G96.8 Other specified disorders of central nervous system
0.000 0.942 0.058
G81.0 Flaccid hemiplegia
0.000 0.942 0.058
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.942 0.058
G97.0 Cerebrospinal fluid leak from spinal puncture
0.000 0.942 0.058
G41.0 Grand mal status epilepticus
0.000 0.942 0.057
G82.5 Tetraplegia, unspecified
0.000 0.943 0.057
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.943 0.057
G70 Myasthenia gravis and other myoneural disorders
0.000 0.943 0.057
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.944 0.056
G04.1 Tropical spastic paraplegia
0.000 0.944 0.056
G04.0 Acute disseminated encephalitis
0.000 0.944 0.056
G82.1 Spastic paraplegia
0.000 0.944 0.056
G44.3 Chronic posttraumatic headache
0.000 0.944 0.056
E07 Other disorders of thyroid
0.000 0.944 0.056
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.944 0.056
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.945 0.055
G00.1 Pneumococcal meningitis
0.000 0.946 0.054
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.946 0.054
G95.0 Syringomyelia and syringobulbia
0.000 0.946 0.054
G43.8 Other migraine
0.000 0.947 0.053
G82.4 Spastic tetraplegia
0.000 0.947 0.053
G41.9 Status epilepticus, unspecified
0.000 0.947 0.053
E03.9 Hypothyroidism, unspecified
0.000 0.947 0.053
G00.8 Other bacterial meningitis
0.000 0.947 0.052
G00.3 Staphylococcal meningitis
0.000 0.947 0.052
G00.2 Streptococcal meningitis
0.000 0.947 0.052
G00.0 Haemophilus meningitis
0.000 0.947 0.052
M35 Other systemic involvement of connective tissue
0.000 0.948 0.052
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.948 0.052
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.948 0.052
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.948 0.052
E03.5 Myxoedema coma
0.000 0.948 0.052
E03.4 Atrophy of thyroid (acquired)
0.000 0.948 0.052
E03.3 Postinfectious hypothyroidism
0.000 0.948 0.052
G44.2 Tension-type headache
0.000 0.948 0.052
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.948 0.051
G82.3 Flaccid tetraplegia
0.000 0.949 0.051
G82.0 Flaccid paraplegia
0.000 0.949 0.051
G47.8 Other sleep disorders
0.000 0.949 0.051
G94.2 Hydrocephalus in other diseases classified elsewhere
0.000 0.949 0.051
G44.8 Other specified headache syndromes
0.000 0.949 0.051
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.950 0.050
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
G02.1 Meningitis in mycoses
0.000 0.950 0.050
G03.8 Meningitis due to other specified causes
0.000 0.950 0.050
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.950 0.050
G03.1 Chronic meningitis
0.000 0.950 0.050
G03.0 Nonpyogenic meningitis
0.000 0.950 0.050
E03.8 Other specified hypothyroidism
0.000 0.950 0.050
G80.8 Other infantile cerebral palsy
0.000 0.950 0.050
E03.1 Congenital hypothyroidism without goitre
0.000 0.951 0.049
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.004 0.951 0.045
G91.0 Communicating hydrocephalus
0.000 0.951 0.049
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.951 0.049
G93 Other disorders of brain
0.000 0.951 0.049
G94.1 Hydrocephalus in neoplastic disease
0.000 0.952 0.048
G91.2 Normal-pressure hydrocephalus
0.000 0.952 0.048
M35.7 Hypermobility syndrome
0.000 0.952 0.048
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.953 0.047
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.953 0.047
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.953 0.047
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.953 0.047
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.953 0.047
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.953 0.047
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.953 0.047
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.953 0.047
G44.1 Vascular headache, not elsewhere classified
0.000 0.953 0.047
G80.9 Infantile cerebral palsy, unspecified
0.000 0.954 0.046
G30.0 Alzheimer's disease with early onset
0.000 0.954 0.046
G20-G26 Extrapyramidal and movement disorders
0.000 0.955 0.045
G44.0 Cluster headache syndrome
0.000 0.955 0.045
G80.4 Ataxic cerebral palsy
0.000 0.955 0.045
G80.3 Dyskinetic cerebral palsy
0.000 0.955 0.045
G93.8 Other specified disorders of brain
0.000 0.955 0.045
G00.9 Bacterial meningitis, unspecified
0.000 0.955 0.044
G90.4 Autonomic dysreflexia
0.000 0.955 0.044
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.955 0.044
G90.8 Other disorders of autonomic nervous system
0.000 0.956 0.044
G80.1 Spastic diplegia
0.000 0.956 0.044
G70.0 Myasthenia gravis
0.000 0.956 0.044
G91.3 Posttraumatic hydrocephalus, unspecified
0.000 0.956 0.044
G83 Other paralytic syndromes
0.000 0.956 0.043
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.957 0.043
E07.8 Other specified disorders of thyroid
0.000 0.957 0.043
G70.9 Myoneural disorder, unspecified
0.000 0.957 0.043
K50.9 Crohn's disease, unspecified
0.043 0.957 0.000
G90.3 Multisystem degeneration
0.000 0.958 0.042
G91.8 Other hydrocephalus
0.000 0.958 0.042
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.958 0.042
G03.9 Meningitis, unspecified
0.000 0.958 0.042
G30.9 Alzheimer's disease, unspecified
0.000 0.958 0.042
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.959 0.041
K51.2 Ulcerative (chronic) proctitis
0.041 0.959 0.000
G71 Primary disorders of muscles
0.000 0.959 0.041
G70.8 Other specified myoneural disorders
0.000 0.959 0.041
G70.2 Congenital and developmental myasthenia
0.000 0.959 0.041
G70.1 Toxic myoneural disorders
0.000 0.959 0.041
G80.0 Spastic cerebral palsy
0.000 0.959 0.041
E07.1 Dyshormogenetic goitre
0.000 0.960 0.040
E07.0 Hypersecretion of calcitonin
0.000 0.960 0.040
G93.0 Cerebral cysts
0.000 0.960 0.040
G62 Other polyneuropathies
0.002 0.960 0.038
K51 Ulcerative colitis
0.040 0.960 0.000
G93.4 Encephalopathy, unspecified
0.000 0.961 0.039
G45.3 Amaurosis fugax
0.000 0.961 0.039
G90.2 Horner's syndrome
0.000 0.962 0.038
K50 Crohn's disease [regional enteritis]
0.038 0.962 0.000
G82.2 Paraplegia, unspecified
0.000 0.962 0.038
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.962 0.038
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.962 0.038
M35.5 Multifocal fibrosclerosis
0.000 0.962 0.038
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.962 0.038
G73.7 Myopathy other diseases classified elsewhere
0.000 0.962 0.037
G73.6 Myopathy in metabolic diseases
0.000 0.962 0.037
G73.5 Myopathy in endocrine diseases
0.000 0.962 0.037
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.962 0.037
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.962 0.037
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.962 0.037
G73.1 Eaton-Lambert syndrome
0.000 0.962 0.037
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.962 0.037
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.963 0.037
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.964 0.036
G95.9 Disease of spinal cord, unspecified
0.000 0.964 0.036
G83.2 Monoplegia of upper limb
0.000 0.964 0.036
G10 Huntington's disease
0.000 0.964 0.035
G64 Other disorders of peripheral nervous system
0.003 0.964 0.032
G93.5 Compression of brain
0.000 0.965 0.035
G91.1 Obstructive hydrocephalus
0.000 0.965 0.035
K50.8 Other Crohn's disease
0.035 0.965 0.000
G93.7 Reye's syndrome
0.000 0.965 0.035
G62.9 Polyneuropathy, unspecified
0.000 0.965 0.035
G62.1 Alcoholic polyneuropathy
0.001 0.965 0.034
G80.2 Infantile hemiplegia
0.000 0.965 0.034
M35.8 Other specified systemic involvement of connective tissue
0.000 0.965 0.035
M06.9 Rheumatoid arthritis, unspecified
0.035 0.965 0.000
K51.9 Ulcerative colitis, unspecified
0.034 0.966 0.000
G23 Other degenerative diseases of basal ganglia
0.000 0.966 0.034
M35.2 Behcet's disease
0.000 0.966 0.034
K51.0 Ulcerative (chronic) enterocolitis
0.034 0.966 0.000
G06.0 Intracranial abscess and granuloma
0.001 0.966 0.034
M35.1 Other overlap syndromes
0.000 0.966 0.034
G14 Postpolio syndrome
0.000 0.966 0.033
K50-K52 Noninfective enteritis and colitis
0.034 0.966 0.000
G72 Other myopathies
0.000 0.966 0.033
M06 Other rheumatoid arthritis
0.033 0.967 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.967 0.033
G30.8 Other Alzheimer's disease
0.000 0.967 0.033
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.033 0.967 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.033 0.967 0.000
K51.5 Mucosal proctocolitis
0.033 0.967 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.967 0.033
G22 Parkinsonism in diseases classified elsewhere
0.000 0.967 0.033
G83.1 Monoplegia of lower limb
0.000 0.968 0.032
M06.0 Seronegative rheumatoid arthritis
0.032 0.968 0.000
G30.1 Alzheimer's disease with late onset
0.000 0.968 0.031
G83.5 Locked-in syndrome
0.000 0.969 0.031
G83.0 Diplegia of upper limbs
0.000 0.969 0.031
G45.2 Multiple and bilateral precerebral artery syndromes
0.000 0.969 0.031
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.001 0.969 0.031
K51.1 Ulcerative (chronic) ileocolitis
0.031 0.969 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.030 0.970 0.000
M06.3 Rheumatoid nodule
0.030 0.970 0.000
G83.8 Other specified paralytic syndromes
0.000 0.970 0.030
G21 Secondary Parkinsonism
0.000 0.970 0.030
S06.3 Focal brain injury
0.000 0.970 0.030
G45.1 Carotid artery syndrome (hemispheric)
0.000 0.970 0.030
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.030 0.970 0.000
G71.9 Primary disorder of muscle, unspecified
0.000 0.970 0.029
G71.8 Other primary disorders of muscles
0.000 0.970 0.029
G71.2 Congenital myopathies
0.000 0.970 0.029
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.030 0.970 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.971 0.029
K51.8 Other ulcerative colitis
0.029 0.971 0.000
G83.3 Monoplegia, unspecified
0.000 0.971 0.029
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.000 0.971 0.029
M06.8 Other specified rheumatoid arthritis
0.029 0.971 0.000
G71.1 Myotonic disorders
0.000 0.971 0.029
G62.2 Polyneuropathy due to other toxic agents
0.001 0.971 0.027
M06.34 Rheumatoid nodule (Hand)
0.028 0.972 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.028 0.972 0.000
G60 Hereditary and idiopathic neuropathy
0.005 0.972 0.023
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.973 0.027
K90-K93 Other diseases of the digestive system
0.000 0.973 0.027
G25 Other extrapyramidal and movement disorders
0.000 0.973 0.027
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.973 0.026
G24 Dystonia
0.000 0.974 0.026
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.974 0.026
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.974 0.026
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.974 0.026
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.974 0.026
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.026 0.974 0.000
K51.4 Pseudopolyposis of colon
0.026 0.974 0.000
G45.0 Vertebro-basilar artery syndrome
0.000 0.974 0.026
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.026 0.974 0.000
G62.0 Drug-induced polyneuropathy
0.001 0.974 0.024
K50.1 Crohn's disease of large intestine
0.025 0.975 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.025 0.975 0.000
G12 Spinal muscular atrophy and related syndromes
0.001 0.975 0.025
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.975 0.025
G23.3 Multiple system atrophy, cerebellar type
0.000 0.975 0.025
G23.2 Striatonigral degeneration
0.000 0.975 0.025
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.975 0.025
G23.0 Hallervorden-Spatz disease
0.000 0.975 0.025
E07.9 Disorder of thyroid, unspecified
0.000 0.975 0.025
G72.1 Alcoholic myopathy
0.000 0.975 0.024
M06.37 Rheumatoid nodule (Ankle and foot)
0.025 0.975 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.024 0.975 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.024 0.975 0.000
G72.3 Periodic paralysis
0.000 0.976 0.024
G72.2 Myopathy due to other toxic agents
0.000 0.976 0.024
G63 Polyneuropathy in diseases classified elsewhere
0.005 0.976 0.020
M06.2 Rheumatoid bursitis
0.024 0.976 0.000
M06.1 Adult-onset Still's disease
0.024 0.976 0.000
I84.9 Unspecified haemorrhoids without complication
0.024 0.976 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.024 0.976 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.024 0.976 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.024 0.976 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.023 0.976 0.000
G72.8 Other specified myopathies
0.000 0.977 0.023
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.023 0.977 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.023 0.977 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.023 0.977 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.023 0.977 0.000
G93.3 Postviral fatigue syndrome
0.000 0.977 0.023
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.023 0.977 0.000
G11 Hereditary ataxia
0.001 0.977 0.022
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.977 0.023
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.977 0.023
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.023 0.977 0.000
G91.9 Hydrocephalus, unspecified
0.000 0.978 0.022
M06.39 Rheumatoid nodule (Site unspecified)
0.022 0.978 0.000
M06.38 Rheumatoid nodule (Other)
0.022 0.978 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.022 0.978 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.022 0.978 0.000
M06.33 Rheumatoid nodule (Forearm)
0.022 0.978 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.022 0.978 0.000
G21.8 Other secondary Parkinsonism
0.000 0.978 0.021
G21.4 Vascular parkinsonism
0.000 0.978 0.021
G21.3 Postencephalitic Parkinsonism
0.000 0.978 0.021
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.978 0.021
G21.0 Malignant neuroleptic syndrome
0.000 0.978 0.021
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.978 0.022
G72.0 Drug-induced myopathy
0.000 0.978 0.021
G25.3 Myoclonus
0.000 0.978 0.022
G45.4 Transient global amnesia
0.000 0.979 0.021
M06.88 Other specified rheumatoid arthritis (Other)
0.021 0.979 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.021 0.979 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.021 0.979 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.021 0.979 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.021 0.979 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.021 0.979 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.021 0.979 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.021 0.979 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.003 0.979 0.018
G83.9 Paralytic syndrome, unspecified
0.000 0.980 0.020
G60.3 Idiopathic progressive neuropathy
0.003 0.980 0.017
G60.2 Neuropathy in association with hereditary ataxia
0.003 0.980 0.017
G60.1 Refsum's disease
0.003 0.980 0.017
G24.3 Spasmodic torticollis
0.000 0.980 0.020
G25.2 Other specified forms of tremor
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.980 0.020
G71.0 Muscular dystrophy
0.000 0.980 0.019
G83.4 Cauda equina syndrome
0.000 0.980 0.020
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.003 0.980 0.016
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.980 0.020
G25.5 Other chorea
0.000 0.980 0.020
G25.4 Drug-induced chorea
0.000 0.980 0.020
M06.32 Rheumatoid nodule (Upper arm)
0.019 0.980 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.019 0.981 0.000
G24.4 Idiopathic orofacial dystonia
0.000 0.981 0.019
G24.2 Idiopathic nonfamilial dystonia
0.000 0.981 0.019
G24.1 Idiopathic familial dystonia
0.000 0.981 0.019
G24.0 Drug-induced dystonia
0.000 0.981 0.019
G24.9 Dystonia, unspecified
0.000 0.981 0.019
G24.8 Other dystonia
0.000 0.981 0.019
E83.4 Disorders of magnesium metabolism
0.000 0.981 0.019
K51.3 Ulcerative (chronic) rectosigmoiditis
0.019 0.981 0.000
G25.1 Drug-induced tremor
0.000 0.981 0.019
M06.4 Inflammatory polyarthropathy
0.018 0.981 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.018 0.982 0.000
G93.6 Cerebral oedema
0.000 0.982 0.018
G12.9 Spinal muscular atrophy, unspecified
0.001 0.982 0.018
G12.8 Other spinal muscular atrophies and related syndromes
0.001 0.982 0.018
G12.1 Other inherited spinal muscular atrophy
0.001 0.982 0.018
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.001 0.982 0.018
G25.0 Essential tremor
0.000 0.982 0.018
Z37.0 Single live birth
0.018 0.982 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.003 0.982 0.014
G63.6 Polyneuropathy in other musculoskeletal disorders
0.003 0.982 0.014
G63.5 Polyneuropathy in systemic connective tissue disorders
0.003 0.982 0.014
G63.4 Polyneuropathy in nutritional deficiency
0.003 0.982 0.014
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.003 0.982 0.014
G63.1 Polyneuropathy in neoplastic disease
0.003 0.982 0.014
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.003 0.982 0.014
M06.19 Adult-onset Still's disease (Site unspecified)
0.017 0.982 0.000
M06.18 Adult-onset Still's disease (Other)
0.017 0.982 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.017 0.982 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.017 0.982 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.017 0.982 0.000
M06.14 Adult-onset Still's disease (Hand)
0.017 0.982 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.017 0.982 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.017 0.982 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.017 0.982 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.017 0.982 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.017 0.982 0.000
M06.28 Rheumatoid bursitis (Other)
0.017 0.982 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.017 0.982 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.017 0.982 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.017 0.982 0.000
M06.24 Rheumatoid bursitis (Hand)
0.017 0.982 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.017 0.982 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.017 0.982 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.017 0.982 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.017 0.982 0.000
G21.9 Secondary Parkinsonism, unspecified
0.000 0.983 0.017
G11.8 Other hereditary ataxias
0.001 0.983 0.016
G11.3 Cerebellar ataxia with defective DNA repair
0.001 0.983 0.016
G11.2 Late-onset cerebellar ataxia
0.001 0.983 0.016
G11.0 Congenital nonprogressive ataxia
0.001 0.983 0.016
G61 Inflammatory polyneuropathy
0.005 0.984 0.011
G72.9 Myopathy, unspecified
0.000 0.984 0.016
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.984 0.016
G20 Parkinson's disease
0.000 0.984 0.016
G11.1 Early-onset cerebellar ataxia
0.001 0.984 0.015
K50.0 Crohn's disease of small intestine
0.016 0.984 0.000
G93.2 Benign intracranial hypertension
0.001 0.985 0.014
G11.4 Hereditary spastic paraplegia
0.001 0.985 0.014
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.015 0.985 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.014
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.014
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.986 0.014
Z37 Outcome of delivery
0.014 0.986 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.014 0.986 0.000
M05-M14 Inflammatory polyarthropathies
0.014 0.986 0.000
M05 Seropositive rheumatoid arthritis
0.014 0.986 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.013 0.986 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.013 0.986 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.013 0.986 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.013 0.986 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.013 0.986 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.013 0.986 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.013 0.986 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.013 0.986 0.000
Z37.2 Twins, both liveborn
0.013 0.987 0.000
N76 Other inflammation of vagina and vulva
0.000 0.987 0.013
G93.9 Disorder of brain, unspecified
0.000 0.987 0.013
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.987 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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