TreeWAS – Variant ID: rs2736332

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M35.0 Sicca syndrome [Sjogren]	0.288	0.712
M35 Other systemic involvement of connective tissue	0.200	0.800
M35.7 Hypermobility syndrome	0.187	0.813
M35.1 Other overlap syndromes	0.165	0.835
M35.8 Other specified systemic involvement of connective tissue	0.152	0.848
M35.9 Systemic involvement of connective tissue, unspecified	0.144	0.856
M35.6 Relapsing panniculitis [Weber-Christian]	0.144	0.856
M35.5 Multifocal fibrosclerosis	0.144	0.856
M35.4 Diffuse (eosinophilic) fasciitis	0.144	0.856
M35.2 Behcet's disease	0.136	0.864
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.103	0.897
M05.9 Seropositive rheumatoid arthritis, unspecified	0.063	0.937
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.062	0.938
N13.8 Other obstructive and reflux uropathy	0.062	0.938
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.061	0.939
N13 Obstructive and reflux uropathy	0.061	0.939
N13.9 Obstructive and reflux uropathy, unspecified	0.056	0.944
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.055	0.945
N10-N16 Renal tubulo-interstitial diseases	0.054	0.946
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.054	0.946
N13.6 Pyonephrosis	0.053	0.947
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.053	0.947
M35.3 Polymyalgia rheumatica	0.053	0.947
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.052	0.948
M34 Systemic sclerosis	0.048	0.952
M34.9 Systemic sclerosis, unspecified	0.048	0.952
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.047	0.953
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.046	0.954
M34.8 Other forms of systemic sclerosis	0.046	0.954
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.045	0.955
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.045	0.955
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.045	0.955
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.045	0.955
M05 Seropositive rheumatoid arthritis	0.045	0.955
N15 Other renal tubulo-interstitial diseases	0.045	0.955
N10 Acute tubulo-interstitial nephritis	0.043	0.957
N13.5 Kinking and stricture of ureter without hydronephrosis	0.043	0.957
N13.7 Vesicoureteral-reflux-associated uropathy	0.042	0.958
M34.1 CR(E)ST syndrome	0.041	0.959
M20-M25 Other joint disorders	0.040	0.960
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.039	0.961
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.038	0.961
N13.3 Other and unspecified hydronephrosis	0.037	0.963
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.037	0.963
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.037	0.963
N15.1 Renal and perinephric abscess	0.037	0.963
M30 Polyarteritis nodosa and related conditions	0.035	0.965
M34.2 Systemic sclerosis induced by drugs and chemicals	0.035	0.965
M34.0 Progressive systemic sclerosis	0.035	0.965
N11 Chronic tubulo-interstitial nephritis	0.035	0.965
N13.4 Hydroureter	0.034	0.966
N15.9 Renal tubulo-interstitial disease, unspecified	0.034	0.966
M05-M14 Inflammatory polyarthropathies	0.033	0.967
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.032	0.967
M05.2 Rheumatoid vasculitis	0.032	0.967
M05.1 Rheumatoid lung disease	0.032	0.967
M05.0 Felty's syndrome	0.032	0.967
N15.8 Other specified renal tubulo-interstitial diseases	0.032	0.968
N15.0 Balkan nephropathy	0.032	0.968
M05.8 Other seropositive rheumatoid arthritis	0.031	0.968
M06 Other rheumatoid arthritis	0.031	0.969
M30.0 Polyarteritis nodosa	0.031	0.969
M33 Dermatopolymyositis	0.030	0.970
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.030	0.970
M06.9 Rheumatoid arthritis, unspecified	0.029	0.971
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.029	0.971
M20 Acquired deformities of fingers and toes	0.029	0.971
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.028	0.972
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.028	0.972
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.028	0.972
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.028	0.972
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.028	0.972
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.028	0.972
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.028	0.972
M20.6 Acquired deformity of toe(s), unspecified	0.028	0.972
N14.4 Toxic nephropathy, not elsewhere classified	0.028	0.972
N14.3 Nephropathy induced by heavy metals	0.028	0.972
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.028	0.972
N14.0 Analgesic nephropathy	0.028	0.972
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.027	0.973
M32 Systemic lupus erythematosus	0.027	0.973
M06.4 Inflammatory polyarthropathy	0.027	0.973
M12 Other specific arthropathies	0.026	0.973
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.026	0.974
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.026	0.974
M08 Juvenile arthritis	0.026	0.974
M20.3 Other deformity of hallux (acquired)	0.026	0.974
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.025	0.975
M30.8 Other conditions related to polyarteritis nodosa	0.025	0.975
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.025	0.975
M30.2 Juvenile polyarteritis	0.025	0.975
M20.0 Deformity of finger(s)	0.025	0.975
N11.8 Other chronic tubulo-interstitial nephritis	0.025	0.975
N11.1 Chronic obstructive pyelonephritis	0.024	0.976
M09 Juvenile arthritis in diseases classified elsewhere	0.024	0.976
M10 Gout	0.024	0.976
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.024	0.976
M05.09 Felty's syndrome (Site unspecified)	0.023	0.976
M05.08 Felty's syndrome (Other)	0.023	0.976
M05.07 Felty's syndrome (Ankle and foot)	0.023	0.976
M05.06 Felty's syndrome (Lower leg)	0.023	0.976
M05.05 Felty's syndrome (Pelvic region and thigh)	0.023	0.976
M05.04 Felty's syndrome (Hand)	0.023	0.976
M05.03 Felty's syndrome (Forearm)	0.023	0.976
M05.02 Felty's syndrome (Upper arm)	0.023	0.976
M05.01 Felty's syndrome (Shoulder region)	0.023	0.976
M05.00 Felty's syndrome (Multiple sites)	0.023	0.976
M05.19 Rheumatoid lung disease (Site unspecified)	0.023	0.976
M05.18 Rheumatoid lung disease (Other)	0.023	0.976
M05.17 Rheumatoid lung disease (Ankle and foot)	0.023	0.976
M05.16 Rheumatoid lung disease (Lower leg)	0.023	0.976
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.023	0.976
M05.14 Rheumatoid lung disease (Hand)	0.023	0.976
M05.13 Rheumatoid lung disease (Forearm)	0.023	0.976
M05.12 Rheumatoid lung disease (Upper arm)	0.023	0.976
M05.11 Rheumatoid lung disease (Shoulder region)	0.023	0.976
M05.10 Rheumatoid lung disease (Multiple sites)	0.023	0.976
M05.29 Rheumatoid vasculitis (Site unspecified)	0.023	0.976
M05.28 Rheumatoid vasculitis (Other)	0.023	0.976
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.023	0.976
M05.26 Rheumatoid vasculitis (Lower leg)	0.023	0.976
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.023	0.976
M05.24 Rheumatoid vasculitis (Hand)	0.023	0.976
M05.23 Rheumatoid vasculitis (Forearm)	0.023	0.976
M05.22 Rheumatoid vasculitis (Upper arm)	0.023	0.976
M05.21 Rheumatoid vasculitis (Shoulder region)	0.023	0.976
M05.20 Rheumatoid vasculitis (Multiple sites)	0.023	0.976
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.023	0.976
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.023	0.976
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.023	0.976
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.023	0.976
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.023	0.976
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.023	0.976
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.023	0.976
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.023	0.976
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.023	0.976
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.023	0.976
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.023	0.977
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.023	0.977
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.023	0.977
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.023	0.977
M05.88 Other seropositive rheumatoid arthritis (Other)	0.023	0.977
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.023	0.977
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.023	0.977
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.023	0.977
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.023	0.977
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.023	0.977
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.023	0.977
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.023	0.977
M06.8 Other specified rheumatoid arthritis	0.023	0.977
M33.2 Polymyositis	0.023	0.977
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.023	0.977
M06.2 Rheumatoid bursitis	0.022	0.978
M06.1 Adult-onset Still's disease	0.022	0.978
M33.9 Dermatopolymyositis, unspecified	0.022	0.978
M33.0 Juvenile dermatomyositis	0.022	0.978
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.022	0.978
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.022	0.978
M33.1 Other dermatomyositis	0.022	0.978
M14 Arthropathies in other diseases classified elsewhere	0.021	0.979
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.021	0.979
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.021	0.979
M36.3 Arthropathy in other blood disorders	0.021	0.979
M36.2 Haemophilic arthropathy	0.021	0.979
M36.1 Arthropathy in neoplastic disease	0.021	0.979
M36.0 Dermato(poly)myositis in neoplastic disease	0.021	0.979
M66 Spontaneous rupture of synovium and tendon	0.021	0.979
M60-M63 Disorders of muscles	0.021	0.979
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.021	0.979
M65-M68 Disorders of synovium and tendon	0.021	0.979
M06.0 Seronegative rheumatoid arthritis	0.021	0.979
M12.2 Villonodular synovitis (pigmented)	0.021	0.979
M06.98 Rheumatoid arthritis, unspecified (Other)	0.020	0.979
M08.0 Juvenile rheumatoid arthritis	0.020	0.980
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.020	0.980
M10.0 Idiopathic gout	0.020	0.980
M12.3 Palindromic rheumatism	0.020	0.980
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.020	0.980
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.020	0.980
M11 Other crystal arthropathies	0.020	0.980
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.020	0.980
M96.0 Pseudarthrosis after fusion or arthrodesis	0.020	0.980
M12.8 Other specific arthropathies, not elsewhere classified	0.020	0.980
M62 Other disorders of muscle	0.020	0.980
M32.9 Systemic lupus erythematosus, unspecified	0.019	0.980
M32.8 Other forms of systemic lupus erythematosus	0.019	0.980
M32.0 Drug-induced systemic lupus erythematosus	0.019	0.980
M07 Psoriatic and enteropathic arthropathies	0.019	0.980
M62.8 Other specified disorders of muscle	0.019	0.981
M06.48 Inflammatory polyarthropathy (Other)	0.019	0.981
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.019	0.981
M06.46 Inflammatory polyarthropathy (Lower leg)	0.019	0.981
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.019	0.981
M06.44 Inflammatory polyarthropathy (Hand)	0.019	0.981
M06.43 Inflammatory polyarthropathy (Forearm)	0.019	0.981
M06.42 Inflammatory polyarthropathy (Upper arm)	0.019	0.981
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.019	0.981
M12.5 Traumatic arthropathy	0.019	0.981
M12.4 Intermittent hydrarthrosis	0.019	0.981
M12.1 Kaschin-Beck disease	0.019	0.981
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.019	0.981
M66.0 Rupture of popliteal cyst	0.019	0.981
M66.2 Spontaneous rupture of extensor tendons	0.019	0.981
M08.9 Juvenile arthritis, unspecified	0.018	0.981
M08.8 Other juvenile arthritis	0.018	0.981
M08.4 Pauciarticular juvenile arthritis	0.018	0.981
M08.3 Juvenile polyarthritis (seronegative)	0.018	0.981
M08.2 Juvenile arthritis with systemic onset	0.018	0.981
M08.1 Juvenile ankylosing spondylitis	0.018	0.981
R73.9 Hyperglycaemia, unspecified	0.019	0.981
M71.2 Synovial cyst of popliteal space [Baker]	0.018	0.982
M20.5 Other deformities of toe(s) (acquired)	0.018	0.982
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.018	0.982
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.018	0.982
M62.88 Other specified disorders of muscle (Other)	0.018	0.982
M62.86 Other specified disorders of muscle (Lower leg)	0.017	0.983
M66.06 Rupture of popliteal cyst-Lower leg	0.017	0.983
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.017	0.983
M09.2 Juvenile arthritis in ulcerative colitis	0.017	0.983
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.017	0.983
M09.0 Juvenile arthritis in psoriasis	0.017	0.983
M71 Other bursopathies	0.017	0.983
M10.4 Other secondary gout	0.017	0.983
M10.3 Gout due to impairment of renal function	0.017	0.983
M10.2 Drug-induced gout	0.017	0.983
M10.1 Lead-induced gout	0.017	0.983
M32.1 Systemic lupus erythematosus with organ or system involvement	0.017	0.983
M66.4 Spontaneous rupture of other tendons	0.017	0.983
M06.3 Rheumatoid nodule	0.017	0.983
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.017	0.983
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.017	0.983
M21 Other acquired deformities of limbs	0.017	0.983
R73 Elevated blood glucose level	0.017	0.983
M70-M79 Other soft tissue disorders	0.017	0.983
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.017	0.983
M20.4 Other hammer toe(s) (acquired)	0.017	0.983
M06.88 Other specified rheumatoid arthritis (Other)	0.016	0.983
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.016	0.983
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.016	0.983
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.016	0.983
M06.84 Other specified rheumatoid arthritis (Hand)	0.016	0.983
M06.83 Other specified rheumatoid arthritis (Forearm)	0.016	0.983
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.016	0.983
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.016	0.983
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.016	0.983
M99 Biomechanical lesions, not elsewhere classified	0.016	0.983
M66.3 Spontaneous rupture of flexor tendons	0.016	0.983
M24 Other specific joint derangements	0.016	0.983
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.016	0.984
M00-M03 Infectious arthropathies	0.016	0.984
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.016	0.984
M06.19 Adult-onset Still's disease (Site unspecified)	0.016	0.984
M06.18 Adult-onset Still's disease (Other)	0.016	0.984
M06.17 Adult-onset Still's disease (Ankle and foot)	0.016	0.984
M06.16 Adult-onset Still's disease (Lower leg)	0.016	0.984
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.016	0.984
M06.14 Adult-onset Still's disease (Hand)	0.016	0.984
M06.13 Adult-onset Still's disease (Forearm)	0.016	0.984
M06.12 Adult-onset Still's disease (Upper arm)	0.016	0.984
M06.11 Adult-onset Still's disease (Shoulder region)	0.016	0.984
M06.10 Adult-onset Still's disease (Multiple sites)	0.016	0.984
M06.29 Rheumatoid bursitis (Site unspecified)	0.016	0.984
M06.28 Rheumatoid bursitis (Other)	0.016	0.984
M06.27 Rheumatoid bursitis (Ankle and foot)	0.016	0.984
M06.26 Rheumatoid bursitis (Lower leg)	0.016	0.984
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.016	0.984
M06.24 Rheumatoid bursitis (Hand)	0.016	0.984
M06.23 Rheumatoid bursitis (Forearm)	0.016	0.984
M06.22 Rheumatoid bursitis (Upper arm)	0.016	0.984
M06.21 Rheumatoid bursitis (Shoulder region)	0.016	0.984
M06.20 Rheumatoid bursitis (Multiple sites)	0.016	0.984
M24.8 Other specific joint derangements, not elsewhere classified	0.016	0.984
M10.02 Idiopathic gout (Upper arm)	0.016	0.984
M66.5 Spontaneous rupture of unspecified tendon	0.016	0.984
M62.81 Other specified disorders of muscle (Shoulder region)	0.016	0.984
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.016	0.984
M10.04 Idiopathic gout (Hand)	0.016	0.984
M13 Other arthritis	0.016	0.984
M10.09 Idiopathic gout (Site unspecified)	0.016	0.984
M62.80 Other specified disorders of muscle (Multiple sites)	0.016	0.984
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.016	0.984
R76.8 Other specified abnormal immunological findings in serum	0.016	0.984
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.015	0.984
M14.4 Arthropathy in amyloidosis	0.015	0.984
M14.3 Lipoid dermatoarthritis	0.015	0.984
M14.2 Diabetic arthropathy	0.015	0.984
M14.1 Crystal arthropathy in other metabolic disorders	0.015	0.984
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.015	0.984
M66.1 Rupture of synovium	0.015	0.984
M60 Myositis	0.015	0.984
M12.39 Palindromic rheumatism (Site unspecified)	0.015	0.985
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.015	0.985
M63 Disorders of muscle in diseases classified elsewhere	0.015	0.985
M61 Calcification and ossification of muscle	0.015	0.985
M14.8 Arthropathies in other specified diseases classified elsewhere	0.015	0.985
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.015	0.985
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.015	0.985
M06.08 Seronegative rheumatoid arthritis (Other)	0.015	0.985
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.015	0.985
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.015	0.985
M06.04 Seronegative rheumatoid arthritis (Hand)	0.015	0.985
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.015	0.985
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.015	0.985
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.015	0.985
R76 Other abnormal immunological findings in serum	0.015	0.985
M10.07 Idiopathic gout (Ankle and foot)	0.015	0.985
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.015	0.985
M12.28 Villonodular synovitis (pigmented) (Other)	0.015	0.985
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.015	0.985
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.015	0.985
M12.24 Villonodular synovitis (pigmented) (Hand)	0.015	0.985
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.015	0.985
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.015	0.985
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.015	0.985
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.015	0.985
M71.9 Bursopathy, unspecified	0.015	0.985
M11.8 Other specified crystal arthropathies	0.015	0.985
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.015	0.985
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.015	0.985
M96.5 Postradiation scoliosis	0.015	0.985
M96.4 Postsurgical lordosis	0.015	0.985
M96.3 Postlaminectomy kyphosis	0.015	0.985
M96.2 Postradiation kyphosis	0.015	0.985
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.015	0.985
M08.08 Juvenile rheumatoid arthritis (Other)	0.015	0.985
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.015	0.985
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.015	0.985
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.015	0.985
M08.04 Juvenile rheumatoid arthritis (Hand)	0.015	0.985
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.015	0.985
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.015	0.985
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.015	0.985
M10.08 Idiopathic gout (Other)	0.015	0.985
M10.06 Idiopathic gout (Lower leg)	0.015	0.985
M10.05 Idiopathic gout (Pelvic region and thigh)	0.015	0.985
M10.03 Idiopathic gout (Forearm)	0.015	0.985
M10.01 Idiopathic gout (Shoulder region)	0.015	0.985
M10.00 Idiopathic gout (Multiple sites)	0.015	0.985
M07.6 Other enteropathic arthropathies	0.015	0.985
M12.38 Palindromic rheumatism (Other)	0.014	0.985
M12.37 Palindromic rheumatism (Ankle and foot)	0.014	0.985
M12.36 Palindromic rheumatism (Lower leg)	0.014	0.985
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.014	0.985
M12.34 Palindromic rheumatism (Hand)	0.014	0.985
M12.33 Palindromic rheumatism (Forearm)	0.014	0.985
M12.32 Palindromic rheumatism (Upper arm)	0.014	0.985
M12.31 Palindromic rheumatism (Shoulder region)	0.014	0.985
M12.30 Palindromic rheumatism (Multiple sites)	0.014	0.985
M11.1 Familial chondrocalcinosis	0.014	0.985
M11.0 Hydroxyapatite deposition disease	0.014	0.985
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.015	0.985
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.014	0.985
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.014	0.985
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.014	0.985
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.014	0.985
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.014	0.985
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.014	0.985
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.014	0.985
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.014	0.985
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.014	0.985
M62.4 Contracture of muscle	0.014	0.985
M62.3 Immobility syndrome (paraplegic)	0.014	0.985
M62.2 Ischaemic infarction of muscle	0.014	0.985
M62.0 Diastasis of muscle	0.014	0.985
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.014	0.986
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.014	0.986
R72 Abnormality of white blood cells, not elsewhere classified	0.014	0.986
M07.5 Arthropathy in ulcerative colitis	0.014	0.986
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.014	0.986
M07.2 Psoriatic spondylitis	0.014	0.986
M07.1 Arthritis mutilans	0.014	0.986
M07.0 Distal interphalangeal psoriatic arthropathy	0.014	0.986
M67 Other disorders of synovium and tendon	0.014	0.986
M62.9 Disorder of muscle, unspecified	0.014	0.986
M11.9 Crystal arthropathy, unspecified	0.014	0.986
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.014	0.986
M62.87 Other specified disorders of muscle (Ankle and foot)	0.014	0.986
M62.84 Other specified disorders of muscle (Hand)	0.014	0.986
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.014	0.986
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.014	0.986
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.014	0.986
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.014	0.986
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.014	0.986
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.014	0.986
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.014	0.986
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.014	0.986
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.014	0.986
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.014	0.986
M12.19 Kaschin-Beck disease (Site unspecified)	0.014	0.986
M12.18 Kaschin-Beck disease (Other)	0.014	0.986
M12.17 Kaschin-Beck disease (Ankle and foot)	0.014	0.986
M12.16 Kaschin-Beck disease (Lower leg)	0.014	0.986
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.014	0.986
M12.14 Kaschin-Beck disease (Hand)	0.014	0.986
M12.13 Kaschin-Beck disease (Forearm)	0.014	0.986
M12.12 Kaschin-Beck disease (Upper arm)	0.014	0.986
M12.11 Kaschin-Beck disease (Shoulder region)	0.014	0.986
M12.10 Kaschin-Beck disease (Multiple sites)	0.014	0.986
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.014	0.986
M12.48 Intermittent hydrarthrosis (Other)	0.014	0.986
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.014	0.986
M12.46 Intermittent hydrarthrosis (Lower leg)	0.014	0.986
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.014	0.986
M12.44 Intermittent hydrarthrosis (Hand)	0.014	0.986
M12.43 Intermittent hydrarthrosis (Forearm)	0.014	0.986
M12.42 Intermittent hydrarthrosis (Upper arm)	0.014	0.986
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.014	0.986
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.014	0.986
M12.59 Traumatic arthropathy (Site unspecified)	0.014	0.986
M12.58 Traumatic arthropathy (Other)	0.014	0.986
M12.57 Traumatic arthropathy (Ankle and foot)	0.014	0.986
M12.56 Traumatic arthropathy (Lower leg)	0.014	0.986
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.014	0.986
M12.54 Traumatic arthropathy (Hand)	0.014	0.986
M12.53 Traumatic arthropathy (Forearm)	0.014	0.986
M12.52 Traumatic arthropathy (Upper arm)	0.014	0.986
M12.51 Traumatic arthropathy (Shoulder region)	0.014	0.986
M12.50 Traumatic arthropathy (Multiple sites)	0.014	0.986
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.014	0.986
M21.7 Unequal limb length (acquired)	0.014	0.986
M62.1 Other rupture of muscle (nontraumatic)	0.014	0.986
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.014	0.986
M66.09 Rupture of popliteal cyst-Site unspec	0.014	0.986
M66.08 Rupture of popliteal cyst-Other	0.014	0.986
M66.07 Rupture of popliteal cyst-Ankle/foot	0.014	0.986
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.014	0.986
M66.04 Rupture of popliteal cyst-Hand	0.014	0.986
M66.03 Rupture of popliteal cyst-Forearm	0.014	0.986
M66.02 Rupture of popliteal cyst-Upper arm	0.014	0.986
M66.01 Rupture of popliteal cyst-Shldr region	0.014	0.986
M66.00 Rupture of popliteal cyst-Mult sites	0.014	0.986
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.014	0.986
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.014	0.986
M66.28 Spontaneous rupture of extensor tendons-Other	0.014	0.986
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.014	0.986
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.014	0.986
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.014	0.986
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.014	0.986
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.014	0.986
M72 Fibroblastic disorders	0.014	0.986
M24.5 Contracture of joint	0.014	0.986
M21.6 Other acquired deformities of ankle and foot	0.014	0.986
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.013	0.986
M08.18 Juvenile ankylosing spondylitis (Other)	0.013	0.986
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.013	0.986
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.013	0.986
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.013	0.986
M08.14 Juvenile ankylosing spondylitis (Hand)	0.013	0.986
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.013	0.986
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.013	0.986
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.013	0.986
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.013	0.986
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.013	0.986
M08.28 Juvenile arthritis with systemic onset (Other)	0.013	0.986
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.013	0.986
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.013	0.986
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.013	0.986
M08.24 Juvenile arthritis with systemic onset (Hand)	0.013	0.986
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.013	0.986
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.013	0.986
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.013	0.986
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.013	0.986
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.013	0.986
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.013	0.986
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.013	0.986
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.013	0.986
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.013	0.986
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.013	0.986
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.013	0.986
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.013	0.986
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.013	0.986
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)	0.013	0.986
M08.49 Pauciarticular juvenile arthritis (Site unspecified)	0.013	0.986
M08.48 Pauciarticular juvenile arthritis (Other)	0.013	0.986
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)	0.013	0.986
M08.46 Pauciarticular juvenile arthritis (Lower leg)	0.013	0.986
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)	0.013	0.986
M08.44 Pauciarticular juvenile arthritis (Hand)	0.013	0.986
M08.43 Pauciarticular juvenile arthritis (Forearm)	0.013	0.986
M08.42 Pauciarticular juvenile arthritis (Upper arm)	0.013	0.986
M08.41 Pauciarticular juvenile arthritis (Shoulder region)	0.013	0.986
M08.40 Pauciarticular juvenile arthritis (Multiple sites)	0.013	0.986
M08.89 Other juvenile arthritis (Site unspecified)	0.013	0.986
M08.88 Other juvenile arthritis (Other)	0.013	0.986
M08.87 Other juvenile arthritis (Ankle and foot)	0.013	0.986
M08.86 Other juvenile arthritis (Lower leg)	0.013	0.986
M08.85 Other juvenile arthritis (Pelvic region and thigh)	0.013	0.986
M08.84 Other juvenile arthritis (Hand)	0.013	0.986
M08.83 Other juvenile arthritis (Forearm)	0.013	0.986
M08.82 Other juvenile arthritis (Upper arm)	0.013	0.986
M08.81 Other juvenile arthritis (Shoulder region)	0.013	0.986
M08.80 Other juvenile arthritis (Multiple sites)	0.013	0.986
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.013	0.986
M08.98 Juvenile arthritis, unspecified (Other)	0.013	0.986
M08.97 Juvenile arthritis, unspecified (Ankle and foot)	0.013	0.986
M08.96 Juvenile arthritis, unspecified (Lower leg)	0.013	0.986
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)	0.013	0.986
M08.94 Juvenile arthritis, unspecified (Hand)	0.013	0.986
M08.93 Juvenile arthritis, unspecified (Forearm)	0.013	0.986
M08.92 Juvenile arthritis, unspecified (Upper arm)	0.013	0.986

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations