TreeWAS – Variant ID: rs2738048

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.274	0.726	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.271	0.729	0.000
T42.4 Benzodiazepines	0.268	0.732	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.232	0.768	0.000
T42.3 Barbiturates	0.219	0.781	0.000
T42.1 Iminostilbenes	0.205	0.795	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.195	0.805	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.195	0.805	0.000
T42.2 Succinimides and oxazolidinediones	0.195	0.805	0.000
T42.0 Hydantoin derivatives	0.193	0.807	0.000
E20-E35 Disorders of other endocrine glands	0.162	0.838	0.000
E22 Hyperfunction of pituitary gland	0.154	0.846	0.000
E27 Other disorders of adrenal gland	0.154	0.846	0.000
E34 Other endocrine disorders	0.151	0.849	0.000
E23 Hypofunction and other disorders of pituitary gland	0.151	0.849	0.000
E28 Ovarian dysfunction	0.149	0.851	0.000
E23.0 Hypopituitarism	0.146	0.854	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.141	0.859	0.000
E27.1 Primary adrenocortical insufficiency	0.139	0.861	0.000
E27.2 Addisonian crisis	0.139	0.861	0.000
E34.9 Endocrine disorder, unspecified	0.138	0.862	0.000
E22.0 Acromegaly and pituitary gigantism	0.137	0.863	0.000
E28.3 Primary ovarian failure	0.132	0.868	0.000
E26 Hyperaldosteronism	0.129	0.871	0.000
E28.2 Polycystic ovarian syndrome	0.125	0.875	0.000
E34.8 Other specified endocrine disorders	0.125	0.875	0.000
E23.2 Diabetes insipidus	0.125	0.875	0.000
E32 Diseases of thymus	0.123	0.876	0.000
E29 Testicular dysfunction	0.123	0.877	0.000
E27.9 Disorder of adrenal gland, unspecified	0.121	0.879	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.118	0.881	0.000
E25 Adrenogenital disorders	0.117	0.882	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.116	0.884	0.000
E31 Polyglandular dysfunction	0.116	0.884	0.000
E30 Disorders of puberty, not elsewhere classified	0.116	0.884	0.000
E27.8 Other specified disorders of adrenal gland	0.114	0.886	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.110	0.889	0.000
E22.8 Other hyperfunction of pituitary gland	0.110	0.889	0.000
E27.5 Adrenomedullary hyperfunction	0.110	0.890	0.000
E27.0 Other adrenocortical overactivity	0.110	0.890	0.000
E34.0 Carcinoid syndrome	0.110	0.890	0.000
E34.5 Androgen resistance syndrome	0.108	0.891	0.000
E34.4 Constitutional tall stature	0.108	0.891	0.000
E34.3 Short stature, not elsewhere classified	0.108	0.891	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.108	0.891	0.000
E34.1 Other hypersecretion of intestinal hormones	0.108	0.891	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.108	0.892	0.000
E23.1 Drug-induced hypopituitarism	0.108	0.892	0.000
E28.9 Ovarian dysfunction, unspecified	0.107	0.893	0.000
E28.8 Other ovarian dysfunction	0.107	0.893	0.000
E28.1 Androgen excess	0.107	0.893	0.000
E28.0 Oestrogen excess	0.107	0.893	0.000
E20 Hypoparathyroidism	0.105	0.895	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.105	0.895	0.000
E22.1 Hyperprolactinaemia	0.105	0.895	0.000
E26.0 Primary hyperaldosteronism	0.104	0.895	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.102	0.898	0.000
E32.9 Disease of thymus, unspecified	0.096	0.904	0.000
E29.1 Testicular hypofunction	0.095	0.905	0.000
E26.9 Hyperaldosteronism, unspecified	0.094	0.906	0.000
E26.8 Other hyperaldosteronism	0.092	0.907	0.000
E26.1 Secondary hyperaldosteronism	0.092	0.907	0.000
E23.6 Other disorders of pituitary gland	0.092	0.908	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.090	0.910	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.089	0.911	0.000
E32.8 Other diseases of thymus	0.089	0.911	0.000
E32.1 Abscess of thymus	0.089	0.911	0.000
E32.0 Persistent hyperplasia of thymus	0.089	0.911	0.000
E24 Cushing's syndrome	0.088	0.911	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.088	0.912	0.000
E29.9 Testicular dysfunction, unspecified	0.088	0.912	0.000
E29.8 Other testicular dysfunction	0.088	0.912	0.000
E29.0 Testicular hyperfunction	0.088	0.912	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.086	0.914	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.085	0.915	0.000
T45.0 Antiallergic and antiemetic drugs	0.085	0.915	0.000
E25.9 Adrenogenital disorder, unspecified	0.084	0.915	0.000
E25.8 Other adrenogenital disorders	0.084	0.915	0.000
E30.9 Disorder of puberty, unspecified	0.083	0.917	0.000
E30.8 Other disorders of puberty	0.083	0.917	0.000
E30.1 Precocious puberty	0.083	0.917	0.000
E30.0 Delayed puberty	0.083	0.917	0.000
E31.9 Polyglandular dysfunction, unspecified	0.083	0.917	0.000
E31.8 Other polyglandular dysfunction	0.083	0.917	0.000
E31.1 Polyglandular hyperfunction	0.083	0.917	0.000
E31.0 Autoimmune polyglandular failure	0.083	0.917	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.083	0.917	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.083	0.917	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.083	0.917	0.000
E23.7 Disorder of pituitary gland, unspecified	0.082	0.918	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.082	0.918	0.000
E21.2 Other hyperparathyroidism	0.079	0.920	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.078	0.922	0.000
T50.8 Diagnostic agents	0.078	0.922	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.077	0.923	0.000
T36 Poisoning by systemic antibiotics	0.076	0.924	0.000
E21.3 Hyperparathyroidism, unspecified	0.076	0.924	0.000
E20.8 Other hypoparathyroidism	0.076	0.924	0.000
E20.1 Pseudohypoparathyroidism	0.076	0.924	0.000
E20.0 Idiopathic hypoparathyroidism	0.076	0.924	0.000
E21.4 Other specified disorders of parathyroid gland	0.075	0.924	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.075	0.925	0.000
T47.0 Histamine H(2)-receptor antagonists	0.074	0.926	0.000
T50.4 Drugs affecting uric acid metabolism	0.074	0.926	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.070	0.930	0.000
T45.5 Anticoagulants	0.068	0.932	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.067	0.933	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.065	0.935	0.000
T47.2 Stimulant laxatives	0.065	0.935	0.000
E20.9 Hypoparathyroidism, unspecified	0.065	0.935	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.065	0.935	0.000
T50.7 Analeptics and opioid receptor antagonists	0.065	0.935	0.000
T50.5 Appetite depressants	0.065	0.935	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.065	0.935	0.000
T50.1 Loop [high-ceiling] diuretics	0.065	0.935	0.000
T50.0 Mineralocorticoids and their antagonists	0.065	0.935	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.064	0.936	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.064	0.936	0.000
E24.8 Other Cushing's syndrome	0.063	0.936	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.063	0.936	0.000
E24.3 Ectopic ACTH syndrome	0.063	0.936	0.000
E24.1 Nelson's syndrome	0.063	0.936	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.063	0.936	0.000
T45.8 Other primarily systemic and haematological agents	0.063	0.936	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.063	0.936	0.000
T45.6 Fibrinolysis-affecting drugs	0.063	0.936	0.000
T45.4 Iron and its compounds	0.063	0.936	0.000
T45.3 Enzymes, not elsewhere classified	0.063	0.936	0.000
E24.0 Pituitary-dependent Cushing's disease	0.063	0.937	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.061	0.939	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.061	0.939	0.000
T47.7 Emetics	0.061	0.939	0.000
T47.6 Antidiarrhoeal drugs	0.061	0.939	0.000
T47.5 Digestants	0.061	0.939	0.000
T47.4 Other laxatives	0.061	0.939	0.000
T47.3 Saline and osmotic laxatives	0.061	0.939	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.061	0.939	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.061	0.939	0.000
T41.2 Other and unspecified general anaesthetics	0.061	0.939	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.060	0.940	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.059	0.941	0.000
E24.9 Cushing's syndrome, unspecified	0.059	0.941	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.059	0.941	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.059	0.941	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.059	0.941	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.059	0.941	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.059	0.941	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.059	0.941	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.059	0.941	0.000
T44.0 Anticholinesterase agents	0.059	0.941	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.059	0.941	0.000
T36.0 Penicillins	0.057	0.942	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.057	0.943	0.000
T41.5 Therapeutic gases	0.056	0.944	0.000
T41.4 Anaesthetic, unspecified	0.056	0.944	0.000
T41.3 Local anaesthetics	0.056	0.944	0.000
T41.1 Intravenous anaesthetics	0.056	0.944	0.000
T41.0 Inhaled anaesthetics	0.056	0.944	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.055	0.944	0.000
T48.5 Anti-common-cold drugs	0.055	0.944	0.000
T48.4 Expectorants	0.055	0.944	0.000
T48.3 Antitussives	0.055	0.944	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.055	0.944	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.055	0.944	0.000
T48.0 Oxytocic drugs	0.055	0.944	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.055	0.945	0.000
T36.9 Systemic antibiotic, unspecified	0.055	0.945	0.000
T36.8 Other systemic antibiotics	0.055	0.945	0.000
T36.7 Antifungal antibiotics, systemically used	0.055	0.945	0.000
T36.6 Rifamycins	0.055	0.945	0.000
T36.5 Aminoglycosides	0.055	0.945	0.000
T36.4 Tetracyclines	0.055	0.945	0.000
T36.3 Macrolides	0.055	0.945	0.000
T36.2 Chloramphenicol group	0.055	0.945	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.055	0.945	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.054	0.946	0.000
T49.9 Topical agent, unspecified	0.054	0.946	0.000
T49.8 Other topical agents	0.054	0.946	0.000
T49.7 Dental drugs, topically applied	0.054	0.946	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.054	0.946	0.000
T49.5 Ophthalmological drugs and preparations	0.054	0.946	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.054	0.946	0.000
T49.3 Emollients, demulcents and protectants	0.054	0.946	0.000
T49.2 Local astringents and local detergents	0.054	0.946	0.000
T49.1 Antipruritics	0.054	0.946	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.051	0.949	0.000
T37.5 Antiviral drugs	0.051	0.949	0.000
T37.4 Anthelminthics	0.051	0.949	0.000
T37.3 Other antiprotozoal drugs	0.051	0.949	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.051	0.949	0.000
T37.1 Antimycobacterial drugs	0.051	0.949	0.000
T37.0 Sulphonamides	0.051	0.949	0.000
T45.2 Vitamins, not elsewhere classified	0.050	0.950	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.050	0.950	0.000
T46.1 Calcium-channel blockers	0.048	0.951	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.047	0.952	0.000
T40.4 Other synthetic narcotics	0.047	0.953	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.047	0.953	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.046	0.954	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.046	0.954	0.000
T46.7 Peripheral vasodilators	0.046	0.954	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.046	0.954	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.046	0.954	0.000
E24.2 Drug-induced Cushing's syndrome	0.046	0.954	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.046	0.954	0.000
T40.5 Cocaine	0.044	0.956	0.000
T38.9 Other and unspecified hormone antagonists	0.044	0.956	0.000
T38.7 Androgens and anabolic congeners	0.044	0.956	0.000
T38.5 Other oestrogens and progestogens	0.044	0.956	0.000
T38.4 Oral contraceptives	0.044	0.956	0.000
T38.2 Antithyroid drugs	0.044	0.956	0.000
T38.0 Glucocorticoids and synthetic analogues	0.044	0.956	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.043	0.957	0.000
E21.0 Primary hyperparathyroidism	0.042	0.958	0.000
T38.1 Thyroid hormones and substitutes	0.042	0.958	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.042	0.958	0.000
T40.8 Lysergide [LSD]	0.042	0.958	0.000
T40.7 Cannabis (derivatives)	0.042	0.958	0.000
T40.3 Methadone	0.042	0.958	0.000
T40.1 Heroin	0.042	0.958	0.000
T40.0 Opium	0.042	0.958	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.042	0.958	0.000
T40.6 Other and unspecified narcotics	0.042	0.958	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.041	0.959	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.034	0.966	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.032	0.968	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.031	0.969	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.026	0.974	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.025	0.975	0.000
T43.6 Psychostimulants with abuse potential	0.025	0.975	0.000
T43.9 Psychotropic drug, unspecified	0.023	0.977	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.023	0.977	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.977	0.022
N72 Inflammatory disease of cervix uteri	0.022	0.978	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.022	0.978	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.022	0.978	0.000
O63.9 Long labour, unspecified	0.000	0.978	0.022
O63 Long labour	0.000	0.979	0.021
Q61.2 Polycystic kidney, adult type	0.000	0.979	0.021
N70-N77 Inflammatory diseases of female pelvic organs	0.020	0.980	0.000
T39.0 Salicylates	0.020	0.980	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.019	0.981	0.000
N71 Inflammatory disease of uterus, except cervix	0.019	0.981	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.019	0.981	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.019	0.981	0.000
T39.4 Antirheumatics, not elsewhere classified	0.019	0.981	0.000
T39.2 Pyrazolone derivatives	0.019	0.981	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.982	0.018
N71.9 Inflammatory disease of uterus, unspecified	0.018	0.982	0.000
N70 Salpingitis and oophoritis	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.017	0.983	0.000
T43.2 Other and unspecified antidepressants	0.017	0.983	0.000
Q61 Cystic kidney disease	0.000	0.983	0.017
N71.1 Chronic inflammatory disease of uterus	0.016	0.983	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.016	0.984	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.015	0.985	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.985	0.015
N76 Other inflammation of vagina and vulva	0.015	0.985	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.015	0.985	0.000
N73 Other female pelvic inflammatory diseases	0.015	0.985	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.985	0.015
N70.0 Acute salpingitis and oophoritis	0.014	0.986	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.014	0.986	0.000
Q61.0 Congenital single renal cyst	0.000	0.986	0.014
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.014	0.986	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
N76.6 Ulceration of vulva	0.014	0.986	0.000
N76.8 Other specified inflammation of vagina and vulva	0.013	0.987	0.000
Q61.5 Medullary cystic kidney	0.000	0.987	0.013
N73.9 Female pelvic inflammatory disease, unspecified	0.013	0.987	0.000
N73.5 Female pelvic peritonitis, unspecified	0.013	0.987	0.000
Q61.8 Other cystic kidney diseases	0.000	0.988	0.012
Q61.1 Polycystic kidney, infantile type	0.000	0.988	0.012
Q61.4 Renal dysplasia	0.000	0.988	0.012
N76.1 Subacute and chronic vaginitis	0.012	0.988	0.000
N70.1 Chronic salpingitis and oophoritis	0.012	0.988	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.988	0.012
N73.0 Acute parametritis and pelvic cellulitis	0.011	0.989	0.000
N71.0 Acute inflammatory disease of uterus	0.011	0.989	0.000
N76.3 Subacute and chronic vulvitis	0.011	0.989	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.011	0.989	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.011	0.989	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.011	0.989	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.011	0.989	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.011	0.989	0.000
N74.0 Tuberculous infection of cervix uteri	0.011	0.989	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.011	0.989	0.000
N73.4 Female chronic pelvic peritonitis	0.011	0.989	0.000
N73.3 Female acute pelvic peritonitis	0.011	0.989	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.011	0.989	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.011	0.989	0.000
N76.2 Acute vulvitis	0.010	0.990	0.000
N76.0 Acute vaginitis	0.009	0.991	0.000
T40.2 Other opioids	0.009	0.991	0.000
N76.5 Ulceration of vagina	0.008	0.991	0.000
N75 Diseases of Bartholin's gland	0.008	0.991	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.008	0.992	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.008	0.992	0.000
N76.4 Abscess of vulva	0.008	0.992	0.000
N75.8 Other diseases of Bartholin's gland	0.007	0.993	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.006	0.994	0.000
B18.2 Chronic viral hepatitis C	0.006	0.994	0.000
Y45.1 Salicylates	0.006	0.994	0.000
H81.0 Meniere's disease	0.006	0.994	0.000
H18.4 Corneal degeneration	0.006	0.994	0.000
H18.5 Hereditary corneal dystrophies	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.995	0.005
H18.1 Bullous keratopathy	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
L50.9 Urticaria, unspecified	0.000	0.996	0.004
F31.9 Bipolar affective disorder, unspecified	0.004	0.996	0.000
F31 Bipolar affective disorder	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.004	0.996	0.000
Z36.8 Other antenatal screening	0.004	0.996	0.000
N75.0 Cyst of Bartholin's gland	0.004	0.996	0.000
B18 Chronic viral hepatitis	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.000	0.996	0.004
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.996	0.004
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
Z47.8 Other specified orthopaedic follow-up care	0.004	0.996	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.004	0.996	0.000
N48.1 Balanoposthitis	0.000	0.996	0.004
F31.7 Bipolar affective disorder, currently in remission	0.004	0.996	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.000	0.996	0.003
H16.2 Keratoconjunctivitis	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.996	0.003
T31.0 Burns involving less than 10% of body surface	0.000	0.996	0.004
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.996	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.996	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.000	0.997	0.003
H18.6 Keratoconus	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
B18.9 Chronic viral hepatitis, unspecified	0.003	0.997	0.000
B18.8 Other chronic viral hepatitis	0.003	0.997	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.003	0.997	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.997	0.003
Q64.8 Other specified congenital malformations of urinary system	0.000	0.997	0.003
Q64.6 Congenital diverticulum of bladder	0.000	0.997	0.003
Q64.5 Congenital absence of bladder and urethra	0.000	0.997	0.003
Q64.4 Malformation of urachus	0.000	0.997	0.003
Q64.2 Congenital posterior urethral valves	0.000	0.997	0.003
Q64.1 Exstrophy of urinary bladder	0.000	0.997	0.003
Q64.0 Epispadias	0.000	0.997	0.003
Q63.2 Ectopic kidney	0.000	0.997	0.003
M84.0 Malunion of fracture	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.000	0.997	0.003
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.997	0.003
Q62.6 Malposition of ureter	0.000	0.997	0.003
Q62.4 Agenesis of ureter	0.000	0.997	0.003
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.997	0.003
Q62.2 Congenital megaloureter	0.000	0.997	0.003
Q62.1 Atresia and stenosis of ureter	0.000	0.997	0.003
Q62.0 Congenital hydronephrosis	0.000	0.997	0.003
K37 Unspecified appendicitis	0.003	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.997	0.003
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
Q63.0 Accessory kidney	0.000	0.997	0.003
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.997	0.003
T90.5 Sequelae of intracranial injury	0.000	0.997	0.003
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.997	0.003
H16.4 Corneal neovascularisation	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
N04.9 Unspecified	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.000	0.997	0.003
Q63.3 Hyperplastic and giant kidney	0.000	0.997	0.003
Z35.4 Supervision of pregnancy with grand multiparity	0.003	0.997	0.000
B37.3 Candidiasis of vulva and vagina	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
M84.04 Malunion of fracture (Hand)	0.003	0.997	0.000
H25.8 Other senile cataract	0.000	0.997	0.003
H17 Corneal scars and opacities	0.003	0.997	0.000
Z35 Supervision of high-risk pregnancy	0.003	0.997	0.000
Z34.8 Supervision of other normal pregnancy	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.997	0.002
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.003	0.997	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H35.6 Retinal haemorrhage	0.000	0.997	0.003
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.997	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.003	0.997	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.997	0.000
M84.08 Malunion of fracture (Other)	0.002	0.997	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.997	0.000
L50 Urticaria	0.000	0.997	0.003
H21.8 Other specified disorders of iris and ciliary body	0.003	0.997	0.000
H93.1 Tinnitus	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.002	0.997	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
H16.8 Other keratitis	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
L50.8 Other urticaria	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.002	0.998	0.000
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.002	0.998	0.000
Z35.6 Supervision of very young primigravida	0.002	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
N02.9 Unspecified	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.001	0.998	0.001
Q60.5 Renal hypoplasia, unspecified	0.001	0.998	0.001
Q60.4 Renal hypoplasia, bilateral	0.001	0.998	0.001
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.001
Q60.1 Renal agenesis, bilateral	0.001	0.998	0.001
T90 Sequelae of injuries of head	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
H21.0 Hyphaema	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
L50.6 Contact urticaria	0.000	0.998	0.002
L50.5 Cholinergic urticaria	0.000	0.998	0.002
L50.4 Vibratory urticaria	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.000	0.998	0.002
L50.2 Urticaria due to cold and heat	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.000	0.998	0.002
H15.0 Scleritis	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.998	0.001
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.000	0.998	0.002
T31 Burns classified according to extent of body surface involved	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.000	0.998	0.002
L50.0 Allergic urticaria	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.998	0.001
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
C25.2 Tail of pancreas	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
T92 Sequelae of injuries of upper limb	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
N04 Nephrotic syndrome	0.002	0.998	0.000
D04.5 Skin of trunk	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
B17.2 Acute hepatitis E	0.002	0.998	0.000
R61.0 Localised hyperhidrosis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations