TreeWAS – Variant ID: rs2739330

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13.3 Other and unspecified hydronephrosis	0.104	0.896	0.000
N13 Obstructive and reflux uropathy	0.100	0.900	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.098	0.902	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.091	0.909	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.081	0.919	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.080	0.920	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.079	0.921	0.000
N13.6 Pyonephrosis	0.077	0.923	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.075	0.925	0.000
N13.4 Hydroureter	0.058	0.942	0.000
M50 Cervical disk disorders	0.052	0.948	0.000
M50.0 Cervical disk disorder with myelopathy	0.052	0.948	0.000
M50.2 Other cervical disk displacement	0.051	0.949	0.000
M50.3 Other cervical disk degeneration	0.050	0.950	0.000
R94.5 Abnormal results of liver function studies	0.000	0.952	0.048
T43.2 Other and unspecified antidepressants	0.000	0.954	0.046
M50.8 Other cervical disk disorders	0.045	0.955	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.957	0.043
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.957	0.043
M50.1 Cervical disk disorder with radiculopathy	0.042	0.958	0.000
N13.8 Other obstructive and reflux uropathy	0.040	0.960	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.960	0.040
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.961	0.039
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.963	0.037
T43.6 Psychostimulants with abuse potential	0.000	0.967	0.033
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.968	0.032
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.969	0.031
T43.9 Psychotropic drug, unspecified	0.000	0.969	0.031
M50.9 Cervical disk disorder, unspecified	0.026	0.973	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.983	0.017
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.985	0.015
N10-N16 Renal tubulo-interstitial diseases	0.012	0.988	0.000
K60.1 Chronic anal fissure	0.000	0.990	0.010
N15 Other renal tubulo-interstitial diseases	0.009	0.991	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.009	0.991	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.008	0.991	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.991	0.008
N11 Chronic tubulo-interstitial nephritis	0.008	0.992	0.000
Q63.0 Accessory kidney	0.000	0.992	0.008
Q61 Cystic kidney disease	0.000	0.992	0.008
Q61.3 Polycystic kidney, unspecified	0.000	0.992	0.008
N15.1 Renal and perinephric abscess	0.008	0.992	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.007	0.993	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
Q63 Other congenital malformations of kidney	0.000	0.993	0.007
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.007	0.993	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.007	0.993	0.000
N15.0 Balkan nephropathy	0.007	0.993	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.007	0.993	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.007	0.993	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.007	0.993	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.007	0.993	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.007	0.993	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.007	0.993	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.007	0.993	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.993	0.007
Q60-Q64 Congenital malformations of the urinary system	0.000	0.993	0.006
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.994	0.006
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.994	0.006
N14.4 Toxic nephropathy, not elsewhere classified	0.006	0.994	0.000
N14.3 Nephropathy induced by heavy metals	0.006	0.994	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.006	0.994	0.000
N14.0 Analgesic nephropathy	0.006	0.994	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.006	0.994	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.006	0.994	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.006	0.994	0.000
Q61.4 Renal dysplasia	0.000	0.994	0.006
N11.1 Chronic obstructive pyelonephritis	0.006	0.994	0.000
Q61.8 Other cystic kidney diseases	0.000	0.994	0.006
Q61.1 Polycystic kidney, infantile type	0.000	0.994	0.006
R09.2 Respiratory arrest	0.000	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.994	0.006
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.005	0.994	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.994	0.006
Q61.5 Medullary cystic kidney	0.000	0.995	0.005
Q63.8 Other specified congenital malformations of kidney	0.000	0.995	0.005
Q63.3 Hyperplastic and giant kidney	0.000	0.995	0.005
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
C80.0 Malignant neoplasm, primary site unknown, so stated	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
I21 Acute myocardial infarction	0.000	0.995	0.005
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.995	0.005
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.995	0.005
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.995	0.005
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.995	0.005
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.995	0.005
Q64 Other congenital malformations of urinary system	0.000	0.995	0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.995	0.005
Q63.2 Ectopic kidney	0.000	0.995	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.995	0.005
T45.0 Antiallergic and antiemetic drugs	0.000	0.995	0.004
S05.9 Injury of eye and orbit, part unspecified	0.000	0.995	0.005
R09.1 Pleurisy	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
Z50.5 Speech therapy	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
N10 Acute tubulo-interstitial nephritis	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.004
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.996	0.004
T38.1 Thyroid hormones and substitutes	0.000	0.996	0.004
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.004
Q62.5 Duplication of ureter	0.000	0.996	0.004
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.004
T50.5 Appetite depressants	0.000	0.996	0.004
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.004
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.004
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.004
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.996	0.004
Q60.6 Potter's syndrome	0.000	0.996	0.004
Q60.5 Renal hypoplasia, unspecified	0.000	0.996	0.004
Q60.4 Renal hypoplasia, bilateral	0.000	0.996	0.004
Q60.3 Renal hypoplasia, unilateral	0.000	0.996	0.004
Q60.1 Renal agenesis, bilateral	0.000	0.996	0.004
T46.1 Calcium-channel blockers	0.000	0.996	0.004
Q62.8 Other congenital malformations of ureter	0.000	0.996	0.004
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.996	0.004
Q62.6 Malposition of ureter	0.000	0.996	0.004
Q62.4 Agenesis of ureter	0.000	0.996	0.004
Q62.0 Congenital hydronephrosis	0.000	0.996	0.004
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.004
Q62.2 Congenital megaloureter	0.000	0.996	0.004
Q62.1 Atresia and stenosis of ureter	0.000	0.996	0.004
T39.4 Antirheumatics, not elsewhere classified	0.000	0.996	0.004
T39.2 Pyrazolone derivatives	0.000	0.996	0.004
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.000	0.996	0.004
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.996	0.003
Q64.8 Other specified congenital malformations of urinary system	0.000	0.996	0.003
Q64.6 Congenital diverticulum of bladder	0.000	0.996	0.003
Q64.5 Congenital absence of bladder and urethra	0.000	0.996	0.003
Q64.2 Congenital posterior urethral valves	0.000	0.996	0.003
Q64.1 Exstrophy of urinary bladder	0.000	0.996	0.003
Q64.0 Epispadias	0.000	0.996	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.996	0.004
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.996	0.004
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.996	0.004
T44.0 Anticholinesterase agents	0.000	0.996	0.004
T50.8 Diagnostic agents	0.000	0.996	0.004
Q64.4 Malformation of urachus	0.000	0.996	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.003
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.996	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.003
T46.7 Peripheral vasodilators	0.000	0.996	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.996	0.003
M50-M54 Other dorsopathies	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
Q60.2 Renal agenesis, unspecified	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
R94 Abnormal results of function studies	0.000	0.997	0.003
D03 Melanoma in situ	0.000	0.997	0.003
S05 Injury of eye and orbit	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.997	0.003
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
N92.5 Other specified irregular menstruation	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
D03.4 Melanoma in situ of scalp and neck	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
L27 Dermatitis due to substances taken internally	0.003	0.997	0.000
C18.1 Appendix	0.000	0.997	0.003
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
D03.5 Melanoma in situ of trunk	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.997	0.002
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.997	0.003
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.997	0.003
R94.2 Abnormal results of pulmonary function studies	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.002
H05.0 Acute inflammation of orbit	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.002
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.997	0.003
M54.64 Pain in thoracic spine (Thoracic region)	0.003	0.997	0.000
S05.8 Other injuries of eye and orbit	0.000	0.997	0.003
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.997	0.003
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.000	0.997	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.002
D03.9 Melanoma in situ, unspecified	0.000	0.997	0.003
S05.7 Avulsion of eye	0.000	0.997	0.003
D03.0 Melanoma in situ of lip	0.000	0.997	0.002
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.997	0.003
R94.7 Abnormal results of other endocrine function studies	0.000	0.997	0.002
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.997	0.003
D03.8 Melanoma in situ of other sites	0.000	0.997	0.002
M79.60 Pain in limb (Multiple sites)	0.000	0.997	0.003
R94.0 Abnormal results of function studies of central nervous system	0.000	0.998	0.002
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.998	0.002
O03.4 Incomplete, without complication	0.000	0.998	0.002
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
M53 Other dorsopathies, not elsewhere classified	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S05.1 Contusion of eyeball and orbital tissues	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
M53.8 Other specified dorsopathies	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
M53.1 Cervicobrachial syndrome	0.002	0.998	0.000
M53.0 Cervicocranial syndrome	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
M53.2 Spinal instabilities	0.002	0.998	0.000
S11 Open wound of neck	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
N32.3 Diverticulum of bladder	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
R94.6 Abnormal results of thyroid function studies	0.001	0.998	0.001
M53.9 Dorsopathy, unspecified	0.002	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.000	0.998	0.002
Y83.3 Surgical operation with formation of external stoma	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
S06 Intracranial injury	0.002	0.998	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.002	0.998	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.002	0.998	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.002	0.998	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.002	0.998	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.002	0.998	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
O20.0 Threatened abortion	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
L60.8 Other nail disorders	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
R94.4 Abnormal results of kidney function studies	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.001	0.998	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.001	0.998	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.001	0.998	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.001	0.998	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.001	0.998	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.001	0.998	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.001	0.998	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.001	0.998	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.001	0.998	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.001	0.998	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.001	0.998	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.001	0.998	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.001	0.998	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.001	0.998	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.001	0.998	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.001	0.998	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.001	0.998	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.001	0.998	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.998	0.002
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.000	0.998	0.002
S11.2 Open wound involving pharynx and cervical oesophagus	0.000	0.998	0.002
S11.1 Open wound involving thyroid gland	0.000	0.998	0.002
S11.0 Open wound involving larynx and trachea	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
Z84.8 Family history of other specified conditions	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.000	0.998	0.002
M53.29 Spinal instabilities (Site unspecified)	0.001	0.998	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.001	0.998	0.000
M53.24 Spinal instabilities (Thoracic region)	0.001	0.998	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.001	0.998	0.000
M53.22 Spinal instabilities (Cervical region)	0.001	0.998	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.001	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.998	0.002
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.998	0.002
O80.8 Other single spontaneous delivery	0.000	0.998	0.002
S11.7 Multiple open wounds of neck	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
S12 Fracture of neck	0.000	0.998	0.002
M53.26 Spinal instabilities (Lumbar region)	0.001	0.998	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.001	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
M53.27 Spinal instabilities (Lumbosacral region)	0.001	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.002
M54.6 Pain in thoracic spine	0.002	0.998	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.001	0.998	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.001	0.998	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.001	0.998	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.998	0.001
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.998	0.001
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.998	0.001
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.001	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.000	0.998	0.001
S10 Superficial injury of neck	0.000	0.998	0.002
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.000	0.998	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.998	0.001
F01 Vascular dementia	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.998	0.000
G83.4 Cauda equina syndrome	0.000	0.998	0.002
S13.5 Sprain and strain of thyroid region	0.000	0.998	0.001
S13.3 Multiple dislocations of neck	0.000	0.998	0.001
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.998	0.001
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.998	0.002
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.998	0.000
L12.0 Bullous pemphigoid	0.001	0.998	0.000
S06.4 Epidural haemorrhage	0.001	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.001
S14.3 Injury of brachial plexus	0.000	0.998	0.001
M53.99 Dorsopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.998	0.001
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.001
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.998	0.000
G45.3 Amaurosis fugax	0.000	0.998	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.999	0.001
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.999	0.001
S17 Crushing injury of neck	0.000	0.999	0.001
S15 Injury of blood vessels at neck level	0.000	0.999	0.001
S18 Traumatic amputation at neck level	0.000	0.999	0.001
S16 Injury of muscle and tendon at neck level	0.000	0.999	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.999	0.000
F01.1 Multi-infarct dementia	0.001	0.999	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.999	0.001
S12.8 Fracture of other parts of neck	0.000	0.999	0.001
S14.6 Injury of other and unspecified nerves of neck	0.000	0.999	0.001
S14.5 Injury of cervical sympathetic nerves	0.000	0.999	0.001
S14.4 Injury of peripheral nerves of neck	0.000	0.999	0.001
S14.2 Injury of nerve root of cervical spine	0.000	0.999	0.001
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.999	0.001
Z84.2 Family history of other diseases of the genito-urinary system	0.001	0.999	0.000
S12.91 Fracture of neck, part unspecified (open)	0.000	0.999	0.001
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.999	0.001
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.001	0.999	0.000
S06.0 Concussion	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
I60 Subarachnoid haemorrhage	0.001	0.999	0.000
M54.69 Pain in thoracic spine-Site unspe	0.001	0.999	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.999	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.999	0.000
M54.66 Pain in thoracic spine-Lumbar	0.001	0.999	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.999	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.999	0.000
M54.62 Pain in thoracic spine-Cervical	0.001	0.999	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.999	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.999	0.000
R61.1 Generalised hyperhidrosis	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.999	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.001	0.999	0.000
H80 Otosclerosis	0.000	0.999	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.999	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.999	0.001
I21.4 Acute subendocardial myocardial infarction	0.000	0.999	0.001
K01.1 Impacted teeth	0.000	0.999	0.001
S10.7 Multiple superficial injuries of neck	0.000	0.999	0.001
S10.1 Other and unspecified superficial injuries of throat	0.000	0.999	0.001
S10.0 Contusion of throat	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
F01.8 Other vascular dementia	0.001	0.999	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.999	0.000
F01.2 Subcortical vascular dementia	0.001	0.999	0.000
F01.0 Vascular dementia of acute onset	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations