TreeWAS – Variant ID: rs27434

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	0.000	0.961	0.039
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.966	0.034
J45.0 Predominantly allergic asthma	0.000	0.972	0.028
M45 Ankylosing spondylitis	0.000	0.975	0.025
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.977	0.023
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.981	0.019
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.982	0.018
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.982	0.018
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.982	0.018
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.982	0.018
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.982	0.018
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.982	0.018
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.985	0.015
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.014	0.986	0.000
L40 Psoriasis	0.000	0.991	0.009
I26 Pulmonary embolism	0.009	0.991	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.008	0.992	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.993	0.007
L40.2 Acrodermatitis continua	0.000	0.993	0.007
L40.1 Generalised pustular psoriasis	0.000	0.993	0.006
L40.4 Guttate psoriasis	0.000	0.994	0.006
L40.8 Other psoriasis	0.000	0.994	0.006
L40.0 Psoriasis vulgaris	0.000	0.994	0.006
K11.2 Sialoadenitis	0.000	0.994	0.006
L40.5 Arthropathic psoriasis	0.000	0.995	0.005
H26.4 After-cataract	0.000	0.995	0.005
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.996	0.004
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.996	0.004
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.996	0.004
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.996	0.004
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.996	0.004
J45 Asthma	0.000	0.996	0.004
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.996	0.004
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.996	0.004
T90 Sequelae of injuries of head	0.000	0.996	0.004
H81.0 Meniere's disease	0.004	0.996	0.000
K81.0 Acute cholecystitis	0.004	0.996	0.000
I24.8 Other forms of acute ischaemic heart disease	0.004	0.996	0.000
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.996	0.003
T90.9 Sequelae of unspecified injury of head	0.000	0.996	0.003
C49.0 Connective and soft tissue of head, face and neck	0.000	0.997	0.003
T91 Sequelae of injuries of neck and trunk	0.000	0.997	0.003
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.997	0.003
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.997	0.003
T90.5 Sequelae of intracranial injury	0.000	0.997	0.003
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.997	0.003
T90.1 Sequelae of open wound of head	0.000	0.997	0.003
Q24 Other congenital malformations of heart	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.003	0.997	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.997	0.003
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.997	0.003
C49.5 Connective and soft tissue of pelvis	0.000	0.997	0.003
M16.9 Coxarthrosis, unspecified	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.997	0.003
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.997	0.003
J45.8 Mixed asthma	0.000	0.997	0.003
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.997	0.003
R07.1 Chest pain on breathing	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.997	0.003
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.997	0.003
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.997	0.003
J45.1 Nonallergic asthma	0.000	0.997	0.002
T91.1 Sequelae of fracture of spine	0.000	0.997	0.003
T90.4 Sequelae of injury of eye and orbit	0.000	0.997	0.003
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.997	0.002
Q24.0 Dextrocardia	0.002	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.997	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.997	0.002
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.998	0.002
T31.0 Burns involving less than 10% of body surface	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.998	0.002
H57.1 Ocular pain	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.002	0.998	0.000
L40-L45 Papulosquamous disorders	0.000	0.998	0.002
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.998	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
S72.3 Fracture of shaft of femur	0.000	0.998	0.002
G91.1 Obstructive hydrocephalus	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
M22.3 Other derangements of patella	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
T95 Sequelae of burns, corrosions and frostbite	0.000	0.998	0.002
D23.0 Skin of lip	0.000	0.998	0.002
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
L44 Other papulosquamous disorders	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.998	0.002
S72.31 Fracture of shaft of femur (open)	0.000	0.998	0.002
D69.0 Allergic purpura	0.002	0.998	0.000
G93.6 Cerebral oedema	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.000	0.998	0.002
L41 Parapsoriasis	0.000	0.998	0.002
D41.4 Bladder	0.000	0.998	0.002
E11.5 With peripheral circulatory complications	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.001
Y54.0 Mineralocorticoids	0.000	0.998	0.001
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.002	0.998	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
M77.02 Medial epicondylitis (Upper arm)	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.002	0.998	0.000
L44.0 Pityriasis rubra pilaris	0.000	0.998	0.001
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.998	0.000
Q25.3 Stenosis of aorta	0.001	0.998	0.000
Q25.2 Atresia of aorta	0.001	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.000	0.998	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.002
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.001	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
I28 Other diseases of pulmonary vessels	0.001	0.998	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.000	0.998	0.001
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.000	0.998	0.001
Y54.5 Other diuretics	0.000	0.998	0.001
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
L44.9 Papulosquamous disorder, unspecified	0.000	0.998	0.001
L44.8 Other specified papulosquamous disorders	0.000	0.998	0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.998	0.001
L44.3 Lichen ruber moniliformis	0.000	0.998	0.001
L44.2 Lichen striatus	0.000	0.998	0.001
L44.1 Lichen nitidus	0.000	0.998	0.001
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.998	0.000
Q22.5 Ebstein's anomaly	0.001	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.998	0.000
Q22.0 Pulmonary valve atresia	0.001	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.000	0.998	0.001
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.000	0.998	0.001
Z81.8 Family history of other mental and behavioural disorders	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.001	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.998	0.000
Q20.4 Double inlet ventricle	0.001	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.998	0.000
Q20.2 Double outlet left ventricle	0.001	0.998	0.000
Q20.1 Double outlet right ventricle	0.001	0.998	0.000
Q20.0 Common arterial trunk	0.001	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.998	0.000
L41.9 Parapsoriasis, unspecified	0.000	0.998	0.001
L41.8 Other parapsoriasis	0.000	0.998	0.001
L41.5 Retiform parapsoriasis	0.000	0.998	0.001
L41.4 Large plaque parapsoriasis	0.000	0.998	0.001
L41.3 Small plaque parapsoriasis	0.000	0.998	0.001
L41.2 Lymphomatoid papulosis	0.000	0.998	0.001
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.998	0.001
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.000	0.998	0.001
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.001
G31.0 Circumscribed brain atrophy	0.000	0.998	0.001
K74.4 Secondary biliary cirrhosis	0.001	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.001	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.001	0.999	0.000
G93.8 Other specified disorders of brain	0.001	0.999	0.000
G93.2 Benign intracranial hypertension	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
G91 Hydrocephalus	0.000	0.999	0.001
D69.2 Other nonthrombocytopenic purpura	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
L42 Pityriasis rosea	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.001	0.999	0.000
L41.1 Pityriasis lichenoides chronica	0.000	0.999	0.001
T98 Sequelae of other and unspecified effects of external causes	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
I28.1 Aneurysm of pulmonary artery	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
T31 Burns classified according to extent of body surface involved	0.000	0.999	0.001
D86.3 Sarcoidosis of skin	0.000	0.999	0.001
F30.9 Manic episode, unspecified	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.999	0.000
I28.8 Other specified diseases of pulmonary vessels	0.001	0.999	0.000
D86 Sarcoidosis	0.000	0.999	0.001
C83.0 Small cell (diffuse)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
H44.0 Purulent endophthalmitis	0.001	0.999	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.999	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.999	0.000
K09.0 Developmental odontogenic cysts	0.000	0.999	0.001
Z54.0 Convalescence following surgery	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
H33.1 Retinoschisis and retinal cysts	0.001	0.999	0.000
F23 Acute and transient psychotic disorders	0.001	0.999	0.000
I87.1 Compression of vein	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.001	0.999	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.999	0.001
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.999	0.000
G93.5 Compression of brain	0.001	0.999	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.999	0.000
T98.2 Sequelae of certain early complications of trauma	0.000	0.999	0.001
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.999	0.001
Y57.5 X-ray contrast media	0.001	0.999	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
G91.8 Other hydrocephalus	0.000	0.999	0.001
T31.9 Burns involving 90% or more of body surface	0.000	0.999	0.001
T31.8 Burns involving 80-89% of body surface	0.000	0.999	0.001
T31.7 Burns involving 70-79% of body surface	0.000	0.999	0.001
T31.6 Burns involving 60-69% of body surface	0.000	0.999	0.001
T31.5 Burns involving 50-59% of body surface	0.000	0.999	0.001
T31.4 Burns involving 40-49% of body surface	0.000	0.999	0.001
T31.3 Burns involving 30-39% of body surface	0.000	0.999	0.001
T31.1 Burns involving 10-19% of body surface	0.000	0.999	0.001
Z89.5 Acquired absence of leg at or below knee	0.001	0.999	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
G93.3 Postviral fatigue syndrome	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
T31.2 Burns involving 20-29% of body surface	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.999	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.999	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.001	0.999	0.000
L43 Lichen planus	0.000	0.999	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.999	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.999	0.000
H27.1 Dislocation of lens	0.000	0.999	0.001
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.999	0.000
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
C22.9 Liver, unspecified	0.001	0.999	0.000
L43.0 Hypertrophic lichen planus	0.000	0.999	0.001
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
W22.2 School, other institution and public administrative area	0.001	0.999	0.000
G93 Other disorders of brain	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
G91.0 Communicating hydrocephalus	0.000	0.999	0.001
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.001	0.999	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.999	0.001
Z97.8 Presence of other specified devices	0.000	0.999	0.001
Y43 Primarily systemic agents	0.001	0.999	0.000
K74.3 Primary biliary cirrhosis	0.001	0.999	0.000
L43.8 Other lichen planus	0.000	0.999	0.001
L43.3 Subacute (active) lichen planus	0.000	0.999	0.001
L43.2 Lichenoid drug reaction	0.000	0.999	0.001
L43.1 Bullous lichen planus	0.000	0.999	0.001
N48.8 Other specified disorders of penis	0.000	0.999	0.001
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.999	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.999	0.001
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.999	0.001
Z64.0 Problems related to unwanted pregnancy	0.000	0.999	0.001
G93.7 Reye's syndrome	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
Y43.9 Primarily systemic agent, unspecified	0.001	0.999	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.001	0.999	0.000
Y43.6 Enzymes, not elsewhere classified	0.001	0.999	0.000
Y43.5 Acidifying and alkalising agents	0.001	0.999	0.000
Y43.0 Antiallergic and antiemetic drugs	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
H44.4 Hypotony of eye	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Z89 Acquired absence of limb	0.001	0.999	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.001	0.999	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
S50.9 Superficial injury of forearm, unspecified	0.000	0.999	0.001
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Z90.3 Acquired absence of part of stomach	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.000	0.999	0.001
Y43.2 Antineoplastic natural products	0.001	0.999	0.000
Y47.1 Benzodiazepines	0.001	0.999	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.999	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.999	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.001	0.999	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.999	0.000
I24 Other acute ischaemic heart diseases	0.001	0.999	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.001	0.999	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.001	0.999	0.000
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
R47.0 Dysphasia and aphasia	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.001	0.999	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.001	0.999	0.000
Z89.1 Acquired absence of hand and wrist	0.001	0.999	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.999	0.001
O14.2 HELLP syndrome	0.001	0.999	0.000
O75.0 Maternal distress during labour and delivery	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
N86 Erosion and ectropion of cervix uteri	0.000	0.999	0.001
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.999	0.001
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.000	0.999	0.001
E11.8 With unspecified complications	0.001	0.999	0.000
G72.8 Other specified myopathies	0.000	0.999	0.001
G72.0 Drug-induced myopathy	0.000	0.999	0.001
M50.9 Cervical disk disorder, unspecified	0.000	0.999	0.001
N71.1 Chronic inflammatory disease of uterus	0.000	0.999	0.001
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.999	0.000
Y43.1 Antineoplastic antimetabolites	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.999	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
E11.1 With ketoacidosis	0.001	0.999	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
Z54.4 Convalescence following treatment of fracture	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.999	0.001
T92 Sequelae of injuries of upper limb	0.000	0.999	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
M43.02 Spondylolysis (Cervical region)	0.000	0.999	0.001
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.999	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.999	0.001
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.999	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.999	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.999	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.999	0.001
F19.1 Harmful use	0.001	0.999	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.999	0.001
K10.2 Inflammatory conditions of jaws	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
Y04.8 Other specified place	0.000	0.999	0.001
Z89.9 Acquired absence of limb, unspecified	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
E11.0 With coma	0.001	0.999	0.000
G72.9 Myopathy, unspecified	0.000	0.999	0.001
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.999	0.001
H44.8 Other disorders of globe	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
S92.1 Fracture of talus	0.001	0.999	0.000
W20.8 Other specified place	0.001	0.999	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.999	0.001
G72.1 Alcoholic myopathy	0.000	0.999	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.999	0.001
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.999	0.001
W21.9 Unspecified place	0.001	0.999	0.000
Z89.2 Acquired absence of upper limb above wrist	0.001	0.999	0.000
M45-M49 Spondylopathies	0.000	0.999	0.001
M19.08 Primary arthrosis of other joints (Other)	0.001	0.999	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.999	0.001
M49.09 Tuberculosis of spine (Site unspecified)	0.000	0.999	0.001
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M49.07 Tuberculosis of spine (Lumbosacral region)	0.000	0.999	0.001
M49.06 Tuberculosis of spine (Lumbar region)	0.000	0.999	0.001
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.000	0.999	0.001
M49.04 Tuberculosis of spine (Thoracic region)	0.000	0.999	0.001
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.000	0.999	0.001
M49.02 Tuberculosis of spine (Cervical region)	0.000	0.999	0.001
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)	0.000	0.999	0.001
M49.00 Tuberculosis of spine (Multiple sites in spine)	0.000	0.999	0.001
M49.19 Brucella spondylitis (Site unspecified)	0.000	0.999	0.001
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M49.17 Brucella spondylitis (Lumbosacral region)	0.000	0.999	0.001
M49.16 Brucella spondylitis (Lumbar region)	0.000	0.999	0.001
M49.15 Brucella spondylitis (Thoracolumbar region)	0.000	0.999	0.001
M49.14 Brucella spondylitis (Thoracic region)	0.000	0.999	0.001
M49.13 Brucella spondylitis (Cervicothoracic region)	0.000	0.999	0.001
M49.12 Brucella spondylitis (Cervical region)	0.000	0.999	0.001
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M49.10 Brucella spondylitis (Multiple sites in spine)	0.000	0.999	0.001
M49.29 Enterobacterial spondylitis (Site unspecified)	0.000	0.999	0.001
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations