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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2743922
log Bayes Factor = 21.7659
Chromosome 6   position 29,699,713  (GRCh37) Explore rs2743922 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.033 0.967
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.145 0.855
G37 Other demyelinating diseases of central nervous system
0.000 0.179 0.821
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.240 0.760
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.262 0.738
G36 Other acute disseminated demyelination
0.000 0.408 0.592
G37.5 Concentric sclerosis [Balo]
0.000 0.411 0.589
G37.4 Subacute necrotising myelitis
0.000 0.411 0.589
G37.2 Central pontine myelinolysis
0.000 0.411 0.589
G37.1 Central demyelination of corpus callosum
0.000 0.411 0.589
G37.0 Diffuse sclerosis
0.000 0.411 0.589
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.439 0.561
G36.9 Acute disseminated demyelination, unspecified
0.000 0.575 0.424
G36.8 Other specified acute disseminated demyelination
0.000 0.575 0.424
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.575 0.424
G36.0 Neuromyelitis optica [Devic]
0.000 0.597 0.403
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.756 0.244
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.757 0.243
E05.9 Thyrotoxicosis, unspecified
0.000 0.759 0.241
K90 Intestinal malabsorption
0.000 0.765 0.235
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.790 0.210
E06 Thyroiditis
0.000 0.803 0.197
E00-E07 Disorders of thyroid gland
0.000 0.804 0.196
E06.3 Autoimmune thyroiditis
0.000 0.807 0.193
Chapter VI Diseases of the nervous system
0.000 0.811 0.189
G40-G47 Episodic and paroxysmal disorders
0.000 0.818 0.182
E06.9 Thyroiditis, unspecified
0.000 0.819 0.181
G30-G32 Other degenerative diseases of the nervous system
0.000 0.824 0.176
E05.5 Thyroid crisis or storm
0.000 0.825 0.175
E05.4 Thyrotoxicosis factitia
0.000 0.825 0.175
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.825 0.175
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.825 0.175
G40 Epilepsy
0.000 0.828 0.172
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.828 0.172
K90.3 Pancreatic steatorrhoea
0.000 0.831 0.169
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.831 0.169
K90.1 Tropical sprue
0.000 0.831 0.169
K90.8 Other intestinal malabsorption
0.000 0.833 0.167
G47.9 Sleep disorder, unspecified
0.000 0.833 0.167
G47 Sleep disorders
0.000 0.834 0.166
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.834 0.166
E05.8 Other thyrotoxicosis
0.000 0.837 0.163
M35.0 Sicca syndrome [Sjogren]
0.000 0.837 0.163
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.843 0.157
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.845 0.155
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.845 0.155
E03 Other hypothyroidism
0.000 0.847 0.153
K90.9 Intestinal malabsorption, unspecified
0.000 0.848 0.152
E06.5 Other chronic thyroiditis
0.000 0.848 0.152
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.851 0.149
G31.8 Other specified degenerative diseases of nervous system
0.000 0.854 0.146
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.854 0.146
G43 Migraine
0.000 0.855 0.145
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.858 0.142
E06.4 Drug-induced thyroiditis
0.000 0.858 0.141
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.858 0.141
E06.0 Acute thyroiditis
0.000 0.858 0.141
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.859 0.140
E00 Congenital iodine-deficiency syndrome
0.000 0.859 0.140
E83 Disorders of mineral metabolism
0.000 0.860 0.139
G43.9 Migraine, unspecified
0.000 0.861 0.139
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.863 0.137
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.865 0.135
G47.2 Disorders of the sleep-wake schedule
0.000 0.867 0.132
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.868 0.132
G81 Hemiplegia
0.000 0.870 0.130
E07 Other disorders of thyroid
0.000 0.871 0.129
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.872 0.128
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.877 0.123
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.877 0.123
E06.1 Subacute thyroiditis
0.000 0.878 0.122
G31.2 Degeneration of nervous system due to alcohol
0.000 0.878 0.122
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.878 0.122
G41 Status epilepticus
0.000 0.878 0.122
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.879 0.121
K51 Ulcerative colitis
0.120 0.880 0.000
G31.0 Circumscribed brain atrophy
0.000 0.880 0.120
G90-G99 Other disorders of the nervous system
0.000 0.880 0.120
K51.2 Ulcerative (chronic) proctitis
0.119 0.881 0.000
G81.9 Hemiplegia, unspecified
0.000 0.883 0.117
K51.9 Ulcerative colitis, unspecified
0.116 0.884 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.884 0.116
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.884 0.116
G44 Other headache syndromes
0.000 0.885 0.115
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.886 0.114
G99 Other disorders of nervous system in diseases classified elsewhere
0.000 0.886 0.114
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.887 0.113
G82 Paraplegia and tetraplegia
0.000 0.888 0.112
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.889 0.111
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.890 0.110
E03.5 Myxoedema coma
0.000 0.890 0.110
E03.4 Atrophy of thyroid (acquired)
0.000 0.890 0.110
E03.3 Postinfectious hypothyroidism
0.000 0.890 0.110
G47.4 Narcolepsy and cataplexy
0.000 0.892 0.108
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.892 0.108
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.893 0.107
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.894 0.106
E03.8 Other specified hypothyroidism
0.000 0.894 0.106
K51.0 Ulcerative (chronic) enterocolitis
0.106 0.894 0.000
G40.9 Epilepsy, unspecified
0.000 0.894 0.106
G46.7 Other lacunar syndromes
0.000 0.895 0.105
G40.8 Other epilepsy
0.000 0.895 0.105
G43.2 Status migrainosus
0.000 0.896 0.104
G40.5 Special epileptic syndromes
0.000 0.897 0.103
G43.0 Migraine without aura [common migraine]
0.000 0.897 0.103
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.897 0.102
G96 Other disorders of central nervous system
0.000 0.898 0.102
E03.1 Congenital hypothyroidism without goitre
0.000 0.899 0.101
E07.8 Other specified disorders of thyroid
0.000 0.899 0.101
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.899 0.101
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.899 0.101
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.899 0.101
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.899 0.101
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.899 0.101
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.899 0.101
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.899 0.101
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.899 0.101
G00 Bacterial meningitis, not elsewhere classified
0.000 0.899 0.100
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.900 0.100
E83.8 Other disorders of mineral metabolism
0.000 0.900 0.100
E83.2 Disorders of zinc metabolism
0.000 0.900 0.100
E83.0 Disorders of copper metabolism
0.000 0.900 0.100
G46.3 Brain stem stroke syndrome
0.000 0.901 0.098
G70-G73 Diseases of myoneural junction and muscle
0.000 0.901 0.098
K51.5 Mucosal proctocolitis
0.098 0.902 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.000 0.902 0.098
G46.6 Pure sensory lacunar syndrome
0.000 0.902 0.098
G46.5 Pure motor lacunar syndrome
0.000 0.902 0.098
G46.2 Posterior cerebral artery syndrome
0.000 0.902 0.098
G46.1 Anterior cerebral artery syndrome
0.000 0.902 0.098
G46.0 Middle cerebral artery syndrome
0.000 0.902 0.098
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.902 0.098
G81.1 Spastic hemiplegia
0.000 0.903 0.097
E83.5 Disorders of calcium metabolism
0.000 0.903 0.097
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.903 0.097
K51.8 Other ulcerative colitis
0.097 0.903 0.000
G46.4 Cerebellar stroke syndrome
0.000 0.903 0.096
K51.1 Ulcerative (chronic) ileocolitis
0.096 0.904 0.000
G03 Meningitis due to other and unspecified causes
0.000 0.904 0.096
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.905 0.095
G06.1 Intraspinal abscess and granuloma
0.000 0.906 0.094
G81.0 Flaccid hemiplegia
0.000 0.907 0.093
G82.1 Spastic paraplegia
0.000 0.907 0.093
G80 Infantile cerebral palsy
0.000 0.907 0.093
E07.1 Dyshormogenetic goitre
0.000 0.907 0.092
E07.0 Hypersecretion of calcitonin
0.000 0.907 0.092
G06.2 Extradural and subdural abscess, unspecified
0.000 0.908 0.092
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.908 0.092
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.908 0.092
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.908 0.091
G96.1 Disorders of meninges, not elsewhere classified
0.000 0.909 0.091
G45.3 Amaurosis fugax
0.000 0.909 0.091
G44.3 Chronic posttraumatic headache
0.000 0.910 0.090
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.910 0.090
K51.4 Pseudopolyposis of colon
0.089 0.911 0.000
G44.2 Tension-type headache
0.000 0.912 0.088
G41.8 Other status epilepticus
0.000 0.913 0.087
G41.2 Complex partial status epilepticus
0.000 0.913 0.087
G41.1 Petit mal status epilepticus
0.000 0.913 0.087
E83.3 Disorders of phosphorus metabolism
0.000 0.913 0.087
G82.5 Tetraplegia, unspecified
0.000 0.913 0.087
G43.3 Complicated migraine
0.000 0.913 0.086
G41.0 Grand mal status epilepticus
0.000 0.914 0.086
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.915 0.085
K50.9 Crohn's disease, unspecified
0.085 0.915 0.000
G82.4 Spastic tetraplegia
0.000 0.916 0.084
G44.8 Other specified headache syndromes
0.000 0.916 0.084
K50-K52 Noninfective enteritis and colitis
0.084 0.916 0.000
K50 Crohn's disease [regional enteritis]
0.084 0.916 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.916 0.084
G47.8 Other sleep disorders
0.000 0.917 0.082
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.918 0.082
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.918 0.082
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.000 0.918 0.082
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.000 0.918 0.082
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.918 0.082
G82.3 Flaccid tetraplegia
0.000 0.919 0.080
G82.0 Flaccid paraplegia
0.000 0.919 0.080
G41.9 Status epilepticus, unspecified
0.000 0.920 0.080
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.920 0.080
G04.1 Tropical spastic paraplegia
0.000 0.920 0.080
G04.0 Acute disseminated encephalitis
0.000 0.920 0.080
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.920 0.079
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.921 0.079
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.921 0.079
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.921 0.079
G43.1 Migraine with aura [classical migraine]
0.000 0.921 0.079
G30 Alzheimer's disease
0.000 0.921 0.078
M35 Other systemic involvement of connective tissue
0.000 0.923 0.077
G70 Myasthenia gravis and other myoneural disorders
0.000 0.923 0.077
G00.1 Pneumococcal meningitis
0.000 0.924 0.076
G96.0 Cerebrospinal fluid leak
0.000 0.924 0.076
G83 Other paralytic syndromes
0.000 0.924 0.076
G44.0 Cluster headache syndrome
0.000 0.924 0.076
K50.8 Other Crohn's disease
0.076 0.924 0.000
G80.8 Other infantile cerebral palsy
0.000 0.926 0.074
G96.9 Disorder of central nervous system, unspecified
0.000 0.926 0.073
M35.7 Hypermobility syndrome
0.000 0.927 0.073
G00.8 Other bacterial meningitis
0.000 0.928 0.072
G00.3 Staphylococcal meningitis
0.000 0.928 0.072
G00.2 Streptococcal meningitis
0.000 0.928 0.072
G00.0 Haemophilus meningitis
0.000 0.928 0.072
G43.8 Other migraine
0.000 0.928 0.072
G44.1 Vascular headache, not elsewhere classified
0.000 0.928 0.072
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.929 0.071
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.929 0.071
G45.2 Multiple and bilateral precerebral artery syndromes
0.000 0.930 0.070
G92 Toxic encephalopathy
0.000 0.931 0.069
G03.8 Meningitis due to other specified causes
0.000 0.931 0.069
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.931 0.069
G03.1 Chronic meningitis
0.000 0.931 0.069
G03.0 Nonpyogenic meningitis
0.000 0.931 0.069
G91 Hydrocephalus
0.000 0.931 0.069
G80.9 Infantile cerebral palsy, unspecified
0.000 0.933 0.067
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.933 0.067
G97.1 Other reaction to spinal and lumbar puncture
0.000 0.933 0.067
G45.1 Carotid artery syndrome (hemispheric)
0.000 0.933 0.067
G80.4 Ataxic cerebral palsy
0.000 0.933 0.067
G80.3 Dyskinetic cerebral palsy
0.000 0.933 0.067
G80.1 Spastic diplegia
0.000 0.934 0.066
G96.8 Other specified disorders of central nervous system
0.000 0.934 0.066
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.934 0.066
G02.1 Meningitis in mycoses
0.000 0.934 0.066
E07.9 Disorder of thyroid, unspecified
0.000 0.934 0.066
G95 Other diseases of spinal cord
0.000 0.935 0.065
G90 Disorders of autonomic nervous system
0.000 0.935 0.065
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.000 0.935 0.065
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.935 0.065
G83.2 Monoplegia of upper limb
0.000 0.936 0.064
I69 Sequelae of cerebrovascular disease
0.000 0.938 0.062
G97.9 Postprocedural disorder of nervous system, unspecified
0.000 0.939 0.061
G97.2 Intracranial hypotension following ventricular shunting
0.000 0.939 0.061
G30.0 Alzheimer's disease with early onset
0.000 0.940 0.060
G00.9 Bacterial meningitis, unspecified
0.000 0.940 0.060
G97.8 Other postprocedural disorders of nervous system
0.000 0.941 0.059
K51.3 Ulcerative (chronic) rectosigmoiditis
0.059 0.941 0.000
G80.0 Spastic cerebral palsy
0.000 0.941 0.058
G70.0 Myasthenia gravis
0.000 0.942 0.058
G70.9 Myoneural disorder, unspecified
0.000 0.942 0.058
G03.9 Meningitis, unspecified
0.000 0.942 0.057
G95.1 Vascular myelopathies
0.000 0.943 0.057
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.943 0.057
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.943 0.057
G83.1 Monoplegia of lower limb
0.000 0.943 0.057
G94.2 Hydrocephalus in other diseases classified elsewhere
0.000 0.943 0.056
M35.8 Other specified systemic involvement of connective tissue
0.000 0.943 0.056
G71 Primary disorders of muscles
0.000 0.944 0.056
G93 Other disorders of brain
0.000 0.944 0.056
G91.0 Communicating hydrocephalus
0.000 0.944 0.056
G45.4 Transient global amnesia
0.000 0.944 0.056
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.944 0.056
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.944 0.056
M35.5 Multifocal fibrosclerosis
0.000 0.944 0.056
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.944 0.056
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.944 0.056
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.944 0.056
G70.8 Other specified myoneural disorders
0.000 0.945 0.055
G70.2 Congenital and developmental myasthenia
0.000 0.945 0.055
G70.1 Toxic myoneural disorders
0.000 0.945 0.055
G20-G26 Extrapyramidal and movement disorders
0.000 0.945 0.055
G91.2 Normal-pressure hydrocephalus
0.000 0.945 0.055
G83.5 Locked-in syndrome
0.000 0.945 0.055
G83.0 Diplegia of upper limbs
0.000 0.945 0.055
G97.0 Cerebrospinal fluid leak from spinal puncture
0.000 0.945 0.055
G82.2 Paraplegia, unspecified
0.000 0.945 0.055
M35.1 Other overlap syndromes
0.000 0.946 0.054
G83.8 Other specified paralytic syndromes
0.000 0.947 0.053
K50.1 Crohn's disease of large intestine
0.053 0.947 0.000
G45.0 Vertebro-basilar artery syndrome
0.000 0.947 0.052
G80.2 Infantile hemiplegia
0.000 0.948 0.052
M35.2 Behcet's disease
0.000 0.948 0.051
G94.1 Hydrocephalus in neoplastic disease
0.000 0.949 0.051
G73.7 Myopathy other diseases classified elsewhere
0.000 0.949 0.051
G73.6 Myopathy in metabolic diseases
0.000 0.949 0.051
G73.5 Myopathy in endocrine diseases
0.000 0.949 0.051
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.949 0.051
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.949 0.051
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.949 0.051
G73.1 Eaton-Lambert syndrome
0.000 0.949 0.051
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.949 0.051
G95.8 Other specified diseases of spinal cord
0.000 0.949 0.051
G83.3 Monoplegia, unspecified
0.000 0.949 0.051
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.949 0.051
N76 Other inflammation of vagina and vulva
0.000 0.949 0.051
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.949 0.050
G93.8 Other specified disorders of brain
0.000 0.950 0.050
N76.8 Other specified inflammation of vagina and vulva
0.000 0.950 0.050
G91.3 Posttraumatic hydrocephalus, unspecified
0.000 0.950 0.050
I69.3 Sequelae of cerebral infarction
0.000 0.951 0.049
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.049 0.951 0.000
N76.4 Abscess of vulva
0.000 0.951 0.049
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.952 0.048
G06.0 Intracranial abscess and granuloma
0.001 0.952 0.047
G30.9 Alzheimer's disease, unspecified
0.000 0.952 0.048
N76.0 Acute vaginitis
0.000 0.952 0.048
G93.4 Encephalopathy, unspecified
0.000 0.953 0.047
G93.0 Cerebral cysts
0.000 0.953 0.047
G90.8 Other disorders of autonomic nervous system
0.000 0.953 0.047
G90.4 Autonomic dysreflexia
0.000 0.953 0.047
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.953 0.047
G91.8 Other hydrocephalus
0.000 0.954 0.046
G95.0 Syringomyelia and syringobulbia
0.000 0.954 0.046
G10 Huntington's disease
0.000 0.954 0.045
G14 Postpolio syndrome
0.000 0.955 0.045
G72 Other myopathies
0.000 0.955 0.045
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.955 0.045
G90.3 Multisystem degeneration
0.000 0.957 0.043
G30.8 Other Alzheimer's disease
0.000 0.957 0.043
N76.3 Subacute and chronic vulvitis
0.000 0.957 0.043
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.958 0.042
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.005 0.958 0.037
G90.2 Horner's syndrome
0.000 0.958 0.042
G93.5 Compression of brain
0.000 0.958 0.042
G30.1 Alzheimer's disease with late onset
0.000 0.959 0.041
G71.1 Myotonic disorders
0.000 0.959 0.041
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.959 0.041
N76.5 Ulceration of vagina
0.000 0.959 0.041
G23 Other degenerative diseases of basal ganglia
0.000 0.959 0.041
Z37.0 Single live birth
0.041 0.959 0.000
G71.9 Primary disorder of muscle, unspecified
0.000 0.959 0.040
G71.8 Other primary disorders of muscles
0.000 0.959 0.040
G71.2 Congenital myopathies
0.000 0.959 0.040
G93.7 Reye's syndrome
0.000 0.959 0.040
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.960 0.040
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.960 0.040
G91.1 Obstructive hydrocephalus
0.000 0.960 0.040
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.960 0.040
G22 Parkinsonism in diseases classified elsewhere
0.000 0.960 0.040
N76.2 Acute vulvitis
0.000 0.961 0.039
N76.1 Subacute and chronic vaginitis
0.000 0.962 0.038
G21 Secondary Parkinsonism
0.000 0.963 0.037
I65.2 Occlusion and stenosis of carotid artery
0.000 0.964 0.036
G83.9 Paralytic syndrome, unspecified
0.000 0.964 0.036
Z37 Outcome of delivery
0.035 0.965 0.000
G25 Other extrapyramidal and movement disorders
0.000 0.965 0.035
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.965 0.035
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.965 0.035
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.965 0.035
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.965 0.035
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.965 0.035
Z37.2 Twins, both liveborn
0.035 0.965 0.000
G83.4 Cauda equina syndrome
0.000 0.966 0.034
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.966 0.034
I60-I69 Cerebrovascular diseases
0.000 0.967 0.033
G12 Spinal muscular atrophy and related syndromes
0.001 0.967 0.033
G72.1 Alcoholic myopathy
0.000 0.967 0.033
G72.3 Periodic paralysis
0.000 0.967 0.032
G72.2 Myopathy due to other toxic agents
0.000 0.967 0.032
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.968 0.032
G95.9 Disease of spinal cord, unspecified
0.000 0.968 0.032
G72.8 Other specified myopathies
0.000 0.968 0.031
N76.6 Ulceration of vulva
0.000 0.969 0.031
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.001 0.969 0.030
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.969 0.031
G11 Hereditary ataxia
0.001 0.969 0.030
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.969 0.031
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.969 0.030
G64 Other disorders of peripheral nervous system
0.004 0.970 0.027
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.970 0.029
G23.3 Multiple system atrophy, cerebellar type
0.000 0.970 0.029
G23.2 Striatonigral degeneration
0.000 0.970 0.029
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.970 0.029
G23.0 Hallervorden-Spatz disease
0.000 0.970 0.029
G72.0 Drug-induced myopathy
0.000 0.970 0.029
K50.0 Crohn's disease of small intestine
0.029 0.971 0.000
Z37.1 Single stillbirth
0.029 0.971 0.000
I63 Cerebral infarction
0.000 0.972 0.028
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.972 0.028
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.973 0.027
G62 Other polyneuropathies
0.002 0.973 0.025
G25.3 Myoclonus
0.000 0.973 0.027
G21.8 Other secondary Parkinsonism
0.000 0.973 0.026
G21.4 Vascular parkinsonism
0.000 0.973 0.026
G21.3 Postencephalitic Parkinsonism
0.000 0.973 0.026
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.973 0.026
G21.0 Malignant neuroleptic syndrome
0.000 0.973 0.026
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.973 0.027
G25.0 Essential tremor
0.000 0.974 0.026
G24 Dystonia
0.000 0.974 0.026
G91.9 Hydrocephalus, unspecified
0.000 0.974 0.026
G25.2 Other specified forms of tremor
0.000 0.974 0.026
E04 Other non-toxic goitre
0.000 0.974 0.026
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.974 0.026
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.974 0.026
Z37.3 Twins, one liveborn and one stillborn
0.026 0.974 0.000
G93.3 Postviral fatigue syndrome
0.000 0.974 0.026
Z37.9 Outcome of delivery unspecified
0.025 0.974 0.000
Z37.7 Other multiple births, all stillborn
0.025 0.974 0.000
Z37.6 Other multiple births, some liveborn
0.025 0.974 0.000
Z37.4 Twins, both stillborn
0.025 0.974 0.000
G25.5 Other chorea
0.000 0.974 0.025
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.975 0.025
G25.4 Drug-induced chorea
0.000 0.975 0.025
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.975 0.025
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.975 0.025
Z37.5 Other multiple births, all liveborn
0.025 0.975 0.000
G60 Hereditary and idiopathic neuropathy
0.005 0.975 0.020
E83.4 Disorders of magnesium metabolism
0.000 0.975 0.025
I65.1 Occlusion and stenosis of basilar artery
0.000 0.975 0.024
G12.9 Spinal muscular atrophy, unspecified
0.001 0.976 0.024
G12.8 Other spinal muscular atrophies and related syndromes
0.001 0.976 0.024
G12.1 Other inherited spinal muscular atrophy
0.001 0.976 0.024
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.001 0.976 0.024
G71.0 Muscular dystrophy
0.000 0.976 0.023
G25.1 Drug-induced tremor
0.000 0.977 0.023
M35.3 Polymyalgia rheumatica
0.000 0.977 0.023
G93.6 Cerebral oedema
0.000 0.977 0.022
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.977 0.022
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.977 0.023
G11.8 Other hereditary ataxias
0.001 0.978 0.022
G11.3 Cerebellar ataxia with defective DNA repair
0.001 0.978 0.022
G11.2 Late-onset cerebellar ataxia
0.001 0.978 0.022
G11.0 Congenital nonprogressive ataxia
0.001 0.978 0.022
E70-E90 Metabolic disorders
0.000 0.978 0.022
G62.1 Alcoholic polyneuropathy
0.001 0.978 0.021
G63 Polyneuropathy in diseases classified elsewhere
0.005 0.979 0.016
S06.3 Focal brain injury
0.000 0.979 0.021
I61 Intracerebral haemorrhage
0.000 0.979 0.021
G21.9 Secondary Parkinsonism, unspecified
0.000 0.979 0.021
G62.9 Polyneuropathy, unspecified
0.000 0.979 0.021
G11.1 Early-onset cerebellar ataxia
0.001 0.979 0.021
I62 Other nontraumatic intracranial haemorrhage
0.000 0.979 0.021
E89.0 Postprocedural hypothyroidism
0.000 0.979 0.021
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.979 0.021
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.980 0.020
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.980 0.020
Z41 Procedures for purposes other than remedying health state
0.020 0.980 0.000
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
G11.4 Hereditary spastic paraplegia
0.001 0.980 0.020
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.980 0.020
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.980 0.020
I63.9 Cerebral infarction, unspecified
0.000 0.980 0.020
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.980 0.020
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.980 0.020
G62.2 Polyneuropathy due to other toxic agents
0.002 0.980 0.018
G93.2 Benign intracranial hypertension
0.000 0.981 0.019
G20 Parkinson's disease
0.000 0.981 0.019
G24.3 Spasmodic torticollis
0.000 0.981 0.019
G24.4 Idiopathic orofacial dystonia
0.000 0.981 0.019
G24.2 Idiopathic nonfamilial dystonia
0.000 0.981 0.019
G24.1 Idiopathic familial dystonia
0.000 0.981 0.019
G24.0 Drug-induced dystonia
0.000 0.981 0.019
E04.8 Other specified non-toxic goitre
0.000 0.981 0.019
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.981 0.019
G72.9 Myopathy, unspecified
0.000 0.981 0.018
E40-E46 Malnutrition
0.000 0.981 0.019
E89.2 Postprocedural hypoparathyroidism
0.000 0.981 0.019
G60.8 Other hereditary and idiopathic neuropathies
0.003 0.981 0.016
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.981 0.018
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.981 0.018
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.981 0.018
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.982 0.018
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.982 0.018
G60.3 Idiopathic progressive neuropathy
0.004 0.982 0.014
G60.2 Neuropathy in association with hereditary ataxia
0.004 0.982 0.014
G60.1 Refsum's disease
0.004 0.982 0.014
G24.9 Dystonia, unspecified
0.000 0.982 0.018
E04.0 Non-toxic diffuse goitre
0.000 0.982 0.018
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.982 0.018
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.004 0.982 0.014
G24.8 Other dystonia
0.000 0.982 0.017
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.982 0.017
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.983 0.017
G93.9 Disorder of brain, unspecified
0.000 0.983 0.017
Z41.8 Other procedures for purposes other than remedying health state
0.017 0.983 0.000
E84 Cystic fibrosis
0.000 0.983 0.017
G62.0 Drug-induced polyneuropathy
0.002 0.983 0.015
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.983 0.016
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.984 0.016
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.984 0.016
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.984 0.016
I84.9 Unspecified haemorrhoids without complication
0.016 0.984 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.984 0.016
E77 Disorders of glycoprotein metabolism
0.000 0.984 0.016
E76 Disorders of glycosaminoglycan metabolism
0.000 0.984 0.016
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.984 0.016
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.984 0.016
I61.8 Other intracerebral haemorrhage
0.000 0.984 0.016
E46 Unspecified protein-energy malnutrition
0.000 0.984 0.016
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.984 0.016
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.984 0.016
E73 Lactose intolerance
0.000 0.984 0.016
G63.8 Polyneuropathy in other diseases classified elsewhere
0.004 0.984 0.012
G63.6 Polyneuropathy in other musculoskeletal disorders
0.004 0.984 0.012
G63.5 Polyneuropathy in systemic connective tissue disorders
0.004 0.984 0.012
G63.4 Polyneuropathy in nutritional deficiency
0.004 0.984 0.012
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.004 0.984 0.012
G63.1 Polyneuropathy in neoplastic disease
0.004 0.984 0.012
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.004 0.984 0.012
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.984 0.015
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.984 0.015
I62.1 Nontraumatic extradural haemorrhage
0.000 0.985 0.015
I71 Aortic aneurysm and dissection
0.000 0.985 0.015
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.985 0.015
E89.1 Postprocedural hypoinsulinaemia
0.000 0.985 0.015
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.985 0.015
I67 Other cerebrovascular diseases
0.000 0.985 0.015
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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