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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2765229
log Bayes Factor = 51.0975
Chromosome 6   position 28,892,919  (GRCh37) Explore rs2765229 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.013 0.987
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.015 0.985
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.018 0.982
E16.2 Hypoglycaemia, unspecified
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.000 0.022 0.978
E10.2 With renal complications
0.000 0.043 0.957
E10.4 With neurological complications
0.000 0.084 0.916
E10.1 With ketoacidosis
0.000 0.088 0.912
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.117 0.883
E05.8 Other thyrotoxicosis
0.000 0.183 0.817
E13 Other specified diabetes mellitus
0.000 0.211 0.789
E16.1 Other hypoglycaemia
0.000 0.215 0.785
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.224 0.776
E10.7 With multiple complications
0.000 0.273 0.727
E10.0 With coma
0.000 0.285 0.714
E14 Unspecified diabetes mellitus
0.000 0.291 0.709
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
E05.5 Thyroid crisis or storm
0.000 0.294 0.706
E05.4 Thyrotoxicosis factitia
0.000 0.294 0.706
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E15 Nondiabetic hypoglycaemic coma
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.299 0.701
E00 Congenital iodine-deficiency syndrome
0.000 0.299 0.701
E40-E46 Malnutrition
0.000 0.317 0.683
E10.5 With peripheral circulatory complications
0.000 0.323 0.677
E13.9 Without complications
0.000 0.359 0.641
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.366 0.633
E10.6 With other specified complications
0.000 0.370 0.629
E14.3 With ophthalmic complications
0.000 0.379 0.621
E07 Other disorders of thyroid
0.000 0.380 0.620
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.420 0.579
E13.3 With ophthalmic complications
0.000 0.424 0.576
E13.8 With unspecified complications
0.000 0.434 0.566
E13.7 With multiple complications
0.000 0.434 0.566
E13.6 With other specified complications
0.000 0.434 0.566
E13.5 With peripheral circulatory complications
0.000 0.434 0.566
E13.4 With neurological complications
0.000 0.434 0.566
E13.2 With renal complications
0.000 0.434 0.566
E13.1 With ketoacidosis
0.000 0.434 0.566
E13.0 With coma
0.000 0.434 0.566
E14.1 With ketoacidosis
0.000 0.438 0.562
E14.6 With other specified complications
0.000 0.454 0.546
E10.8 With unspecified complications
0.000 0.467 0.532
E06 Thyroiditis
0.000 0.474 0.525
E14.4 With neurological complications
0.000 0.481 0.519
E14.7 With multiple complications
0.000 0.492 0.508
E12.9 Without complications
0.000 0.492 0.507
E12.8 With unspecified complications
0.000 0.492 0.507
E12.7 With multiple complications
0.000 0.492 0.507
E12.6 With other specified complications
0.000 0.492 0.507
E12.5 With peripheral circulatory complications
0.000 0.492 0.507
E12.4 With neurological complications
0.000 0.492 0.507
E12.3 With ophthalmic complications
0.000 0.492 0.507
E12.2 With renal complications
0.000 0.492 0.507
E12.1 With ketoacidosis
0.000 0.492 0.507
E12.0 With coma
0.000 0.492 0.507
E14.8 With unspecified complications
0.000 0.496 0.503
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.497 0.502
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.497 0.502
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.497 0.502
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.497 0.502
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.497 0.502
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.497 0.502
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.497 0.502
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.497 0.502
E07.8 Other specified disorders of thyroid
0.000 0.507 0.493
E14.2 Withrenal complications
0.000 0.508 0.492
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.492 0.508 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.510 0.490
E45 Retarded development following protein-energy malnutrition
0.000 0.510 0.490
E43 Unspecified severe protein-energy malnutrition
0.000 0.510 0.490
E42 Marasmic kwashiorkor
0.000 0.510 0.490
E41 Nutritional marasmus
0.000 0.510 0.490
E40 Kwashiorkor
0.000 0.510 0.490
E14.5 With peripheral circulatory complications
0.000 0.512 0.488
E14.0 With coma
0.000 0.521 0.479
E46 Unspecified protein-energy malnutrition
0.000 0.531 0.469
E07.1 Dyshormogenetic goitre
0.000 0.555 0.445
E07.0 Hypersecretion of calcitonin
0.000 0.555 0.445
E06.9 Thyroiditis, unspecified
0.000 0.584 0.416
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.598 0.402
E06.1 Subacute thyroiditis
0.000 0.617 0.383
E03 Other hypothyroidism
0.000 0.622 0.378
E06.4 Drug-induced thyroiditis
0.000 0.623 0.377
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.623 0.377
E06.0 Acute thyroiditis
0.000 0.623 0.377
E70-E90 Metabolic disorders
0.001 0.629 0.370
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.633 0.367
K90 Intestinal malabsorption
0.000 0.637 0.363
E78.2 Mixed hyperlipidaemia
0.000 0.640 0.360
E44.1 Mild protein-energy malnutrition
0.000 0.648 0.351
E44.0 Moderate protein-energy malnutrition
0.000 0.648 0.351
E06.5 Other chronic thyroiditis
0.000 0.650 0.350
E78.5 Hyperlipidaemia, unspecified
0.000 0.657 0.343
E50-E64 Other nutritional deficiencies
0.000 0.660 0.340
E78.1 Pure hyperglyceridaemia
0.000 0.678 0.322
E65-E68 Obesity and other hyperalimentation
0.000 0.685 0.315
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.706 0.294
E74 Other disorders of carbohydrate metabolism
0.000 0.706 0.293
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.709 0.291
E78.6 Lipoprotein deficiency
0.000 0.710 0.290
E88 Other metabolic disorders
0.000 0.710 0.289
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.715 0.285
E85 Amyloidosis
0.000 0.720 0.280
E78.3 Hyperchylomicronaemia
0.000 0.721 0.279
E11 Non-insulin-dependent diabetes mellitus
0.000 0.724 0.276
E84 Cystic fibrosis
0.001 0.728 0.272
E03.5 Myxoedema coma
0.000 0.729 0.271
E03.4 Atrophy of thyroid (acquired)
0.000 0.729 0.271
E03.3 Postinfectious hypothyroidism
0.000 0.729 0.271
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.730 0.270
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.731 0.269
E73 Lactose intolerance
0.000 0.731 0.269
E07.9 Disorder of thyroid, unspecified
0.000 0.732 0.268
E77 Disorders of glycoprotein metabolism
0.001 0.734 0.266
E76 Disorders of glycosaminoglycan metabolism
0.001 0.734 0.266
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.734 0.266
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.734 0.266
E03.1 Congenital hypothyroidism without goitre
0.000 0.736 0.264
K90.3 Pancreatic steatorrhoea
0.000 0.739 0.260
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.739 0.260
K90.1 Tropical sprue
0.000 0.739 0.260
K90.8 Other intestinal malabsorption
0.000 0.745 0.255
E83 Disorders of mineral metabolism
0.176 0.745 0.079
E70 Disorders of aromatic amino-acid metabolism
0.001 0.746 0.254
E79 Disorders of purine and pyrimidine metabolism
0.001 0.749 0.250
E54 Ascorbic acid deficiency
0.000 0.750 0.249
E88.9 Metabolic disorder, unspecified
0.000 0.754 0.246
E51 Thiamine deficiency
0.000 0.755 0.245
E72 Other disorders of amino-acid metabolism
0.001 0.755 0.244
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.756 0.244
E63 Other nutritional deficiencies
0.000 0.756 0.244
E50 Vitamin A deficiency
0.000 0.756 0.244
E60 Dietary zinc deficiency
0.000 0.756 0.244
E59 Dietary selenium deficiency
0.000 0.756 0.244
E52 Niacin deficiency [pellagra]
0.000 0.756 0.244
E11.1 With ketoacidosis
0.000 0.757 0.243
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.759 0.241
I73 Other peripheral vascular diseases
0.000 0.759 0.241
I73.9 Peripheral vascular disease, unspecified
0.000 0.760 0.240
E85.4 Organ-limited amyloidosis
0.000 0.762 0.238
E11.6 With other specified complications
0.000 0.763 0.237
I77 Other disorders of arteries and arterioles
0.000 0.764 0.236
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.764 0.236
E75.5 Other lipid storage disorders
0.000 0.764 0.235
E56 Other vitamin deficiencies
0.000 0.768 0.232
I77.6 Arteritis, unspecified
0.000 0.772 0.228
E11.2 With renal complications
0.000 0.774 0.226
E67 Other hyperalimentation
0.000 0.774 0.226
E68 Sequelae of hyperalimentation
0.000 0.774 0.226
E03.8 Other specified hypothyroidism
0.000 0.775 0.225
E88.2 Lipomatosis, not elsewhere classified
0.000 0.775 0.225
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.776 0.224
E55 Vitamin D deficiency
0.000 0.779 0.221
I73.0 Raynaud's syndrome
0.000 0.780 0.220
E78.4 Other hyperlipidaemia
0.000 0.780 0.219
I74 Arterial embolism and thrombosis
0.000 0.782 0.218
E75.2 Other sphingolipidosis
0.000 0.784 0.215
E58 Dietary calcium deficiency
0.000 0.785 0.215
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.786 0.214
E75.6 Lipid storage disorder, unspecified
0.000 0.789 0.211
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.789 0.211
E75.3 Sphingolipidosis, unspecified
0.000 0.789 0.211
E75.1 Other gangliosidosis
0.000 0.789 0.211
E75.0 GM2 gangliosidosis
0.000 0.789 0.211
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.789 0.210
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.789 0.210
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.789 0.210
E74.2 Disorders of galactose metabolism
0.000 0.789 0.210
E74.1 Disorders of fructose metabolism
0.000 0.789 0.210
I72 Other aneurysm
0.000 0.793 0.207
E85.3 Secondary systemic amyloidosis
0.000 0.794 0.206
E74.0 Glycogen storage disease
0.000 0.794 0.206
E11.0 With coma
0.000 0.794 0.206
E85.8 Other amyloidosis
0.000 0.795 0.204
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.796 0.204
I77.8 Other specified disorders of arteries and arterioles
0.000 0.797 0.203
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.799 0.201
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.799 0.201
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.799 0.201
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.799 0.200
E11.7 With multiple complications
0.000 0.802 0.198
I74.5 Embolism and thrombosis of iliac artery
0.000 0.803 0.197
E84.9 Cystic fibrosis, unspecified
0.000 0.804 0.196
E73.9 Lactose intolerance, unspecified
0.000 0.804 0.196
E84.8 Cystic fibrosis with other manifestations
0.001 0.804 0.195
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.804 0.195
E73.8 Other lactose intolerance
0.000 0.807 0.193
E73.1 Secondary lactase deficiency
0.000 0.807 0.193
E73.0 Congenital lactase deficiency
0.000 0.807 0.193
E71.3 Disorders of fatty-acid metabolism
0.001 0.809 0.191
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.809 0.191
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.809 0.191
E71.0 Maple-syrup-urine disease
0.001 0.809 0.191
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.809 0.191
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.809 0.191
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.809 0.191
E76.2 Other mucopolysaccharidoses
0.001 0.809 0.191
E76.1 Mucopolysaccharidosis, type II
0.001 0.809 0.191
E76.0 Mucopolysaccharidosis, type I
0.001 0.809 0.191
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.809 0.191
E77.8 Other disorders of glycoprotein metabolism
0.001 0.809 0.191
E77.1 Defects in glycoprotein degradation
0.001 0.809 0.191
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.809 0.191
E88.8 Other specified metabolic disorders
0.000 0.810 0.190
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.810 0.190
E61 Deficiency of other nutrient elements
0.000 0.813 0.187
I72.4 Aneurysm of artery of lower extremity
0.000 0.813 0.187
I77.1 Stricture of artery
0.000 0.816 0.184
I70 Atherosclerosis
0.000 0.816 0.184
M45.X9 Ankylosing spondylitis (Site unspecified)
0.184 0.816 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.817 0.183
E83.8 Other disorders of mineral metabolism
0.126 0.817 0.056
E83.2 Disorders of zinc metabolism
0.126 0.817 0.056
E83.0 Disorders of copper metabolism
0.126 0.817 0.056
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.817 0.182
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.817 0.182
E70.2 Disorders of tyrosine metabolism
0.001 0.817 0.182
E70.1 Other hyperphenylalaninaemias
0.001 0.817 0.182
E70.0 Classical phenylketonuria
0.001 0.817 0.182
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.817 0.182
E83.9 Disorder of mineral metabolism, unspecified
0.125 0.820 0.055
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.820 0.180
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.820 0.180
E79.1 Lesch-Nyhan syndrome
0.001 0.820 0.180
I77.3 Arterial fibromuscular dysplasia
0.000 0.820 0.180
I83 Varicose veins of lower extremities
0.178 0.822 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.822 0.178
E51.2 Wernicke's encephalopathy
0.000 0.823 0.176
K90.9 Intestinal malabsorption, unspecified
0.000 0.824 0.176
E51.9 Thiamine deficiency, unspecified
0.000 0.824 0.176
E51.8 Other manifestations of thiamine deficiency
0.000 0.824 0.176
E51.1 Beriberi
0.000 0.824 0.176
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.824 0.175
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.824 0.175
E72.5 Disorders of glycine metabolism
0.001 0.824 0.175
E72.4 Disorders of ornithine metabolism
0.001 0.824 0.175
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.824 0.175
E72.2 Disorders of urea cycle metabolism
0.001 0.824 0.175
E50.9 Vitamin A deficiency, unspecified
0.000 0.825 0.175
E50.8 Other manifestations of vitamin A deficiency
0.000 0.825 0.175
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.825 0.175
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.825 0.175
E50.5 Vitamin A deficiency with night blindness
0.000 0.825 0.175
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.825 0.175
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.825 0.175
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.825 0.175
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.825 0.175
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.825 0.175
E63.9 Nutritional deficiency, unspecified
0.000 0.825 0.175
E63.8 Other specified nutritional deficiencies
0.000 0.825 0.175
E63.1 Imbalance of constituents of food intake
0.000 0.825 0.175
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.825 0.175
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.825 0.175
E64.8 Sequelae of other nutritional deficiencies
0.000 0.825 0.175
E64.3 Sequelae of rickets
0.000 0.825 0.175
E64.2 Sequelae of vitamin C deficiency
0.000 0.825 0.175
E64.1 Sequelae of vitamin A deficiency
0.000 0.825 0.175
E64.0 Sequelae of protein-energy malnutrition
0.000 0.825 0.175
E88.3 Tumour lysis syndrome
0.000 0.826 0.174
E11.8 With unspecified complications
0.000 0.827 0.173
I72.3 Aneurysm of iliac artery
0.000 0.828 0.172
E72.0 Disorders of amino-acid transport
0.001 0.828 0.171
E70.3 Albinism
0.001 0.829 0.170
I77.5 Necrosis of artery
0.000 0.830 0.170
I77.4 Coeliac artery compression syndrome
0.000 0.830 0.170
E53 Deficiency of other B group vitamins
0.000 0.831 0.169
I77.2 Rupture of artery
0.000 0.832 0.168
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.832 0.168
E65 Localised adiposity
0.000 0.833 0.167
E83.3 Disorders of phosphorus metabolism
0.146 0.833 0.021
E56.9 Vitamin deficiency, unspecified
0.000 0.833 0.167
E56.8 Deficiency of other vitamins
0.000 0.833 0.167
E56.0 Deficiency of vitamin E
0.000 0.833 0.167
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.835 0.164
E67.8 Other specified hyperalimentation
0.000 0.838 0.162
E67.3 Hypervitaminosis D
0.000 0.838 0.162
E67.2 Megavitamin-B6 syndrome
0.000 0.838 0.162
E67.1 Hypercarotenaemia
0.000 0.838 0.162
E67.0 Hypervitaminosis A
0.000 0.838 0.162
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.839 0.161
I72.0 Aneurysm of carotid artery
0.000 0.840 0.160
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.840 0.160
E55.0 Rickets, active
0.000 0.841 0.159
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.842 0.158
E56.1 Deficiency of vitamin K
0.000 0.845 0.155
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.847 0.153
E78.8 Other disorders of lipoprotein metabolism
0.000 0.849 0.151
I72.1 Aneurysm of artery of upper extremity
0.000 0.849 0.151
I72.9 Aneurysm of unspecified site
0.000 0.850 0.150
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.851 0.149
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.851 0.149
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.853 0.147
E85.9 Amyloidosis, unspecified
0.001 0.857 0.142
I70.8 Atherosclerosis of other arteries
0.000 0.859 0.140
E06.3 Autoimmune thyroiditis
0.001 0.863 0.136
I70.1 Atherosclerosis of renal artery
0.000 0.864 0.136
E55.9 Vitamin D deficiency, unspecified
0.000 0.864 0.136
E61.9 Deficiency of nutrient element, unspecified
0.000 0.865 0.134
E61.8 Deficiency of other specified nutrient elements
0.000 0.865 0.134
E61.7 Deficiency of multiple nutrient elements
0.000 0.865 0.134
E61.6 Vanadium deficiency
0.000 0.865 0.134
E61.5 Molybdenum deficiency
0.000 0.865 0.134
E61.4 Chromium deficiency
0.000 0.865 0.134
E61.3 Manganese deficiency
0.000 0.865 0.134
E61.0 Copper deficiency
0.000 0.865 0.134
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.865 0.134
I72.2 Aneurysm of renal artery
0.000 0.867 0.133
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.870 0.130
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.870 0.129
I79.1 Aortitis in diseases classified elsewhere
0.000 0.872 0.128
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.872 0.128
E53.9 Vitamin B deficiency, unspecified
0.000 0.873 0.127
I70.9 Generalised and unspecified atherosclerosis
0.000 0.874 0.126
E20-E35 Disorders of other endocrine glands
0.000 0.875 0.125
E14.9 Without complications
0.000 0.876 0.124
I70.0 Atherosclerosis of aorta
0.000 0.876 0.124
E61.2 Magnesium deficiency
0.000 0.878 0.121
I78 Diseases of capillaries
0.000 0.878 0.121
E53.1 Pyridoxine deficiency
0.000 0.879 0.121
E53.0 Riboflavin deficiency
0.000 0.879 0.121
E11.5 With peripheral circulatory complications
0.000 0.881 0.119
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.882 0.118
E80.2 Other porphyria
0.000 0.882 0.118
E11.3 With ophthalmic complications
0.000 0.883 0.117
E78.0 Pure hypercholesterolaemia
0.000 0.883 0.117
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.116 0.884 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.888 0.112
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.112 0.888 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.112 0.888 0.000
E24 Cushing's syndrome
0.000 0.889 0.111
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.890 0.110
E80.5 Crigler-Najjar syndrome
0.001 0.890 0.110
E80.3 Defects of catalase and peroxydase
0.001 0.890 0.110
E80.0 Hereditary erythropoietic porphyria
0.001 0.890 0.110
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.890 0.110
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.891 0.109
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.892 0.108
I72.8 Aneurysm of other specified arteries
0.000 0.893 0.107
I86 Varicose veins of other sites
0.105 0.895 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.104 0.896 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.898 0.102
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.899 0.101
E61.1 Iron deficiency
0.000 0.901 0.099
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.902 0.098
M45 Ankylosing spondylitis
0.097 0.903 0.000
I89.0 Lymphoedema, not elsewhere classified
0.097 0.903 0.000
I86.4 Gastric varices
0.097 0.903 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.904 0.096
E80.6 Other disorders of bilirubin metabolism
0.001 0.905 0.095
I74.8 Embolism and thrombosis of other arteries
0.000 0.905 0.095
I85 Oesophageal varices
0.094 0.905 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.906 0.094
E20 Hypoparathyroidism
0.000 0.906 0.094
I81 Portal vein thrombosis
0.094 0.906 0.000
E83.4 Disorders of magnesium metabolism
0.056 0.907 0.037
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.093 0.907 0.000
E80.1 Porphyria cutanea tarda
0.001 0.907 0.092
E24.9 Cushing's syndrome, unspecified
0.000 0.908 0.092
I86.8 Varicose veins of other specified sites
0.092 0.908 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.909 0.091
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.909 0.090
E21.3 Hyperparathyroidism, unspecified
0.000 0.909 0.091
E25 Adrenogenital disorders
0.000 0.910 0.090
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.910 0.090
E32 Diseases of thymus
0.000 0.910 0.090
E30 Disorders of puberty, not elsewhere classified
0.000 0.910 0.090
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.911 0.089
E31 Polyglandular dysfunction
0.000 0.911 0.089
E28 Ovarian dysfunction
0.000 0.913 0.087
E24.2 Drug-induced Cushing's syndrome
0.000 0.914 0.085
I85.9 Oesophageal varices without bleeding
0.085 0.915 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.916 0.084
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.920 0.080
E24.8 Other Cushing's syndrome
0.000 0.920 0.080
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.920 0.080
E24.3 Ectopic ACTH syndrome
0.000 0.920 0.080
E24.1 Nelson's syndrome
0.000 0.920 0.080
I86.3 Vulval varices
0.080 0.920 0.000
I78.8 Other diseases of capillaries
0.000 0.921 0.079
I86.2 Pelvic varices
0.079 0.921 0.000
E29 Testicular dysfunction
0.000 0.922 0.078
M45.X6 Ankylosing spondylitis (Lumbar region)
0.077 0.923 0.000
I82 Other venous embolism and thrombosis
0.077 0.923 0.000
E34 Other endocrine disorders
0.000 0.924 0.076
I89.1 Lymphangitis
0.076 0.924 0.000
I86.0 Sublingual varices
0.075 0.925 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.075 0.925 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.075 0.925 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.928 0.071
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.070 0.930 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.070 0.930 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.070 0.930 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.070 0.930 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.070 0.930 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.070 0.930 0.000
E21.2 Other hyperparathyroidism
0.000 0.930 0.070
I88 Nonspecific lymphadenitis
0.069 0.931 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.931 0.069
I87 Other disorders of veins
0.069 0.931 0.000
E20.8 Other hypoparathyroidism
0.000 0.932 0.067
E20.1 Pseudohypoparathyroidism
0.000 0.932 0.067
E20.0 Idiopathic hypoparathyroidism
0.000 0.932 0.067
I78.9 Disease of capillaries, unspecified
0.000 0.933 0.067
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.935 0.065
E25.9 Adrenogenital disorder, unspecified
0.000 0.935 0.065
E25.8 Other adrenogenital disorders
0.000 0.935 0.065
E30.9 Disorder of puberty, unspecified
0.000 0.935 0.065
E30.8 Other disorders of puberty
0.000 0.935 0.065
E30.1 Precocious puberty
0.000 0.935 0.065
E30.0 Delayed puberty
0.000 0.935 0.065
E32.9 Disease of thymus, unspecified
0.000 0.935 0.065
E32.8 Other diseases of thymus
0.000 0.935 0.065
E32.1 Abscess of thymus
0.000 0.935 0.065
E32.0 Persistent hyperplasia of thymus
0.000 0.935 0.065
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.935 0.065
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.935 0.065
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.935 0.065
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.936 0.064
E31.9 Polyglandular dysfunction, unspecified
0.000 0.936 0.064
E31.8 Other polyglandular dysfunction
0.000 0.936 0.064
E31.1 Polyglandular hyperfunction
0.000 0.936 0.064
E28.3 Primary ovarian failure
0.000 0.936 0.064
E31.0 Autoimmune polyglandular failure
0.000 0.937 0.063
E28.9 Ovarian dysfunction, unspecified
0.000 0.938 0.062
E28.8 Other ovarian dysfunction
0.000 0.938 0.062
E28.1 Androgen excess
0.000 0.938 0.062
E28.0 Oestrogen excess
0.000 0.938 0.062
I85.0 Oesophageal varices with bleeding
0.061 0.939 0.000
I82.0 Budd-Chiari syndrome
0.061 0.939 0.000
I82.8 Embolism and thrombosis of other specified veins
0.061 0.939 0.000
E26 Hyperaldosteronism
0.000 0.940 0.060
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.059 0.941 0.000
E83.5 Disorders of calcium metabolism
0.007 0.941 0.052
E03.9 Hypothyroidism, unspecified
0.000 0.942 0.058
E29.9 Testicular dysfunction, unspecified
0.000 0.942 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.943 0.057
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.943 0.057
E11.4 With neurological complications
0.000 0.943 0.057
E29.8 Other testicular dysfunction
0.000 0.943 0.056
E29.0 Testicular hyperfunction
0.000 0.943 0.056
E34.3 Short stature, not elsewhere classified
0.000 0.944 0.056
I87.8 Other specified disorders of veins
0.056 0.944 0.000
I82.1 Thrombophlebitis migrans
0.055 0.945 0.000
E34.5 Androgen resistance syndrome
0.000 0.945 0.054
E34.4 Constitutional tall stature
0.000 0.945 0.054
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.945 0.054
E34.1 Other hypersecretion of intestinal hormones
0.000 0.945 0.054
I82.2 Embolism and thrombosis of vena cava
0.054 0.946 0.000
E34.8 Other specified endocrine disorders
0.000 0.947 0.053
I82.3 Embolism and thrombosis of renal vein
0.052 0.948 0.000
E22 Hyperfunction of pituitary gland
0.000 0.949 0.051
E80.4 Gilbert's syndrome
0.000 0.949 0.051
E34.9 Endocrine disorder, unspecified
0.000 0.949 0.050
I88.1 Chronic lymphadenitis, except mesenteric
0.049 0.950 0.000
I87.0 Postphlebitic syndrome
0.049 0.950 0.000
I88.8 Other nonspecific lymphadenitis
0.049 0.951 0.000
I87.9 Disorder of vein, unspecified
0.049 0.951 0.000
E34.0 Carcinoid syndrome
0.000 0.953 0.047
I88.0 Nonspecific mesenteric lymphadenitis
0.046 0.953 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.045 0.955 0.000
R31 Unspecified haematuria
0.044 0.956 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.956 0.043
E26.8 Other hyperaldosteronism
0.000 0.957 0.043
E26.1 Secondary hyperaldosteronism
0.000 0.957 0.043
I88.9 Nonspecific lymphadenitis, unspecified
0.043 0.957 0.000
E29.1 Testicular hypofunction
0.000 0.957 0.043
I86.1 Scrotal varices
0.041 0.959 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.041 0.959 0.000
E04 Other non-toxic goitre
0.003 0.961 0.037
E26.9 Hyperaldosteronism, unspecified
0.001 0.961 0.038
E23.7 Disorder of pituitary gland, unspecified
0.000 0.962 0.037
E22.8 Other hyperfunction of pituitary gland
0.000 0.963 0.037
E86 Volume depletion
0.000 0.963 0.037
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.036 0.963 0.000
E22.1 Hyperprolactinaemia
0.000 0.963 0.036
E21.0 Primary hyperparathyroidism
0.000 0.965 0.035
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.965 0.035
I87.1 Compression of vein
0.034 0.966 0.000
I80 Phlebitis and thrombophlebitis
0.033 0.967 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.969 0.031
E23.1 Drug-induced hypopituitarism
0.000 0.969 0.031
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.970 0.030
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.971 0.028
E53.8 Deficiency of other specified B group vitamins
0.000 0.971 0.029
E04.8 Other specified non-toxic goitre
0.002 0.972 0.026
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.028 0.972 0.000
E66 Obesity
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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