TreeWAS – Variant ID: rs2794256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z43.3 Attention to colostomy	0.000	0.971	0.029
O16 Unspecified maternal hypertension	0.000	0.979	0.021
T42.4 Benzodiazepines	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.021	0.979	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.020	0.980	0.000
T39.0 Salicylates	0.020	0.980	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.981	0.019
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.019	0.981	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.019	0.981	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.981	0.019
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.018	0.982	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.017	0.983	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
Z45.8 Adjustment and management of other implanted devices	0.017	0.983	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.017	0.983	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.016	0.983	0.000
T40.2 Other opioids	0.016	0.984	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.984	0.016
T36 Poisoning by systemic antibiotics	0.016	0.984	0.000
O14.0 Moderate preeclampsia	0.000	0.984	0.016
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.984	0.016
T45.0 Antiallergic and antiemetic drugs	0.016	0.984	0.000
T42.0 Hydantoin derivatives	0.015	0.984	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.985	0.000
T42.1 Iminostilbenes	0.015	0.985	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.015	0.985	0.000
Z43 Attention to artificial openings	0.000	0.985	0.015
T41 Poisoning by anaesthetics and therapeutic gases	0.015	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.015	0.985	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.015	0.985	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.985	0.015
T40.6 Other and unspecified narcotics	0.015	0.985	0.000
T50.4 Drugs affecting uric acid metabolism	0.015	0.985	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.015	0.985	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.985	0.014
Z43.0 Attention to tracheostomy	0.000	0.985	0.014
T50.6 Antidotes and chelating agents, not elsewhere classified	0.014	0.986	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T40.1 Heroin	0.014	0.986	0.000
Z43.5 Attention to cyctostomy	0.000	0.986	0.014
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.014	0.986	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.014	0.986	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.986	0.000
T42.3 Barbiturates	0.014	0.986	0.000
T36.3 Macrolides	0.014	0.986	0.000
T45.5 Anticoagulants	0.014	0.986	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.013	0.986	0.000
T46.7 Peripheral vasodilators	0.013	0.986	0.000
O15 Eclampsia	0.000	0.986	0.013
T40.5 Cocaine	0.013	0.986	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.013	0.986	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.013	0.986	0.000
T50.1 Loop [high-ceiling] diuretics	0.013	0.986	0.000
T50.7 Analeptics and opioid receptor antagonists	0.013	0.987	0.000
T50.5 Appetite depressants	0.013	0.987	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.013	0.987	0.000
T50.0 Mineralocorticoids and their antagonists	0.013	0.987	0.000
T50.8 Diagnostic agents	0.013	0.987	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.013	0.987	0.000
T40.8 Lysergide [LSD]	0.013	0.987	0.000
T40.7 Cannabis (derivatives)	0.013	0.987	0.000
T40.0 Opium	0.013	0.987	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.013	0.987	0.000
T45.4 Iron and its compounds	0.013	0.987	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.013	0.987	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.987	0.013
T40.3 Methadone	0.013	0.987	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.013	0.987	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.013	0.987	0.000
T43.2 Other and unspecified antidepressants	0.013	0.987	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.012	0.987	0.000
T45.8 Other primarily systemic and haematological agents	0.012	0.987	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.012	0.987	0.000
T45.6 Fibrinolysis-affecting drugs	0.012	0.987	0.000
T45.3 Enzymes, not elsewhere classified	0.012	0.987	0.000
T45.2 Vitamins, not elsewhere classified	0.012	0.988	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O12.1 Gestational proteinuria	0.000	0.988	0.012
T36.8 Other systemic antibiotics	0.012	0.988	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.988	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
T36.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
T36.6 Rifamycins	0.012	0.988	0.000
T36.5 Aminoglycosides	0.012	0.988	0.000
T36.2 Chloramphenicol group	0.012	0.988	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.012	0.988	0.000
Z43.8 Attention to other artificial openings	0.000	0.988	0.012
T47.2 Stimulant laxatives	0.011	0.988	0.000
O14.2 HELLP syndrome	0.000	0.988	0.011
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.011	0.989	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.011	0.989	0.000
T47.7 Emetics	0.011	0.989	0.000
T47.5 Digestants	0.011	0.989	0.000
T47.3 Saline and osmotic laxatives	0.011	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.011	0.989	0.000
T43.9 Psychotropic drug, unspecified	0.011	0.989	0.000
Z43.9 Attention to unspecified artificial opening	0.000	0.989	0.011
Z43.7 Attention to artificial vagina	0.000	0.989	0.011
T41.5 Therapeutic gases	0.011	0.989	0.000
T41.4 Anaesthetic, unspecified	0.011	0.989	0.000
T41.3 Local anaesthetics	0.011	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
T41.1 Intravenous anaesthetics	0.011	0.989	0.000
T41.0 Inhaled anaesthetics	0.011	0.989	0.000
T46.1 Calcium-channel blockers	0.011	0.989	0.000
T49.9 Topical agent, unspecified	0.011	0.989	0.000
T49.8 Other topical agents	0.011	0.989	0.000
T49.7 Dental drugs, topically applied	0.011	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.989	0.000
T49.2 Local astringents and local detergents	0.011	0.989	0.000
T49.1 Antipruritics	0.011	0.989	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.989	0.000
O12.0 Gestational oedema	0.000	0.989	0.011
T47.4 Other laxatives	0.011	0.989	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.011	0.989	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.010	0.989	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.990	0.010
O15.1 Eclampsia in labour	0.000	0.990	0.010
O15.0 Eclampsia in pregnancy	0.000	0.990	0.010
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.010	0.990	0.000
T48.4 Expectorants	0.010	0.990	0.000
T48.3 Antitussives	0.010	0.990	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.010	0.990	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.010	0.990	0.000
T48.0 Oxytocic drugs	0.010	0.990	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.990	0.010
T36.0 Penicillins	0.010	0.990	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.990	0.010
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.990	0.010
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.990	0.000
T37.5 Antiviral drugs	0.009	0.990	0.000
T37.4 Anthelminthics	0.009	0.990	0.000
T37.3 Other antiprotozoal drugs	0.009	0.990	0.000
T37.1 Antimycobacterial drugs	0.009	0.990	0.000
T37.0 Sulphonamides	0.009	0.990	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.990	0.010
O15.2 Eclampsia in the puerperium	0.000	0.990	0.009
T48.5 Anti-common-cold drugs	0.009	0.991	0.000
O14.1 Severe preeclampsia	0.000	0.991	0.009
T48.6 Antiasthmatics, not elsewhere classified	0.009	0.991	0.000
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.991	0.009
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.009	0.991	0.000
T38.0 Glucocorticoids and synthetic analogues	0.009	0.991	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.009	0.991	0.000
T38.9 Other and unspecified hormone antagonists	0.009	0.991	0.000
T38.7 Androgens and anabolic congeners	0.009	0.991	0.000
T38.4 Oral contraceptives	0.009	0.991	0.000
T38.2 Antithyroid drugs	0.009	0.991	0.000
T38.5 Other oestrogens and progestogens	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.009	0.991	0.000
J15.1 Pneumonia due to Pseudomonas	0.000	0.992	0.008
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
J15.5 Pneumonia due to Escherichia coli	0.000	0.992	0.008
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
Z43.1 Attention to gastrostomy	0.000	0.992	0.008
J15.8 Other bacterial pneumonia	0.000	0.992	0.008
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
Z95.1 Presence of aortocoronary bypass graft	0.008	0.992	0.000
T40.4 Other synthetic narcotics	0.007	0.992	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.007	0.992	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.992	0.000
T44.0 Anticholinesterase agents	0.007	0.992	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.007	0.993	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.993	0.007
J15.3 Pneumonia due to streptococcus, group B	0.000	0.993	0.007
J15.4 Pneumonia due to other streptococci	0.000	0.993	0.007
J15.9 Bacterial pneumonia, unspecified	0.000	0.993	0.007
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.993	0.007
J15.2 Pneumonia due to staphylococcus	0.000	0.993	0.007
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.006	0.994	0.000
T82.3 Mechanical complication of other vascular grafts	0.006	0.994	0.000
O14.9 Preeclampsia, unspecified	0.000	0.994	0.006
S01.0 Open wound of scalp	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.994	0.000
O20.8 Other haemorrhage in early pregnancy	0.006	0.994	0.000
O20 Haemorrhage in early pregnancy	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T78.3 Angioneurotic oedema	0.000	0.995	0.005
R45.8 Other symptoms and signs involving emotional state	0.005	0.995	0.000
Z85.6 Personal history of leukaemia	0.005	0.995	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.995	0.005
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.996	0.004
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.996	0.004
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
H65.3 Chronic mucoid otitis media	0.000	0.996	0.004
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.996	0.004
K09.2 Other cysts of jaw	0.004	0.996	0.000
Z04.5 Examination and observation following other inflicted injury	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.996	0.004
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.996	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.996	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.001	0.997	0.003
H60.9 Otitis externa, unspecified	0.000	0.997	0.003
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.000	0.997	0.003
K29.4 Chronic atrophic gastritis	0.000	0.997	0.003
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.997	0.003
K56.2 Volvulus	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
I87.1 Compression of vein	0.000	0.997	0.003
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
J09-J18 Influenza and pneumonia	0.000	0.997	0.003
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
N60 Benign mammary dysplasia	0.000	0.997	0.003
H65 Nonsuppurative otitis media	0.000	0.997	0.003
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.003	0.997	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.003	0.997	0.000
J14 Pneumonia due to Haemophilus influenzae	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.000	0.997	0.003
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
Z04.1 Examination and observation following transport accident	0.003	0.997	0.000
O21 Excessive vomiting in pregnancy	0.003	0.997	0.000
Z04 Examination and observation for other reasons	0.003	0.997	0.000
L50.0 Allergic urticaria	0.000	0.997	0.003
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
N60.9 Benign mammary dysplasia, unspecified	0.000	0.997	0.002
O21.2 Late vomiting of pregnancy	0.002	0.997	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.003
Z81.8 Family history of other mental and behavioural disorders	0.000	0.997	0.003
M05.1 Rheumatoid lung disease	0.002	0.997	0.000
O20.0 Threatened abortion	0.003	0.997	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.002	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.002
Z04.8 Examination and observation for other specified reasons	0.003	0.997	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.000	0.997	0.002
T82.4 Mechanical complication of vascular dialysis catheter	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.001	0.998	0.002
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.000	0.998	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
N60.8 Other benign mammary dysplasias	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.000	0.998	0.002
Z43.2 Attention to ileostomy	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
J09 Influenza due to certain identified influenza virus	0.000	0.998	0.002
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.998	0.002
J16.8 Pneumonia due to other specified infectious organisms	0.000	0.998	0.002
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.998	0.000
Z04.4 Examination and observation following alleged rape and seduction	0.002	0.998	0.000
Z04.0 Blood-alcohol and blood-drug test	0.002	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.998	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.002	0.998	0.000
E55 Vitamin D deficiency	0.000	0.998	0.002
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
J16.0 Chlamydial pneumonia	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
M05.08 Felty's syndrome (Other)	0.002	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
Z04.2 Examination and observation following work accident	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.998	0.002
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.998	0.002
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.998	0.002
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.998	0.002
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.998	0.002
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.998	0.002
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.998	0.002
C25.0 Head of pancreas	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.000	0.998	0.002
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
S06 Intracranial injury	0.000	0.998	0.002
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.000	0.998	0.002
Z04.6 General psychiatric examination, requested by authority	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S06.3 Focal brain injury	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.000	0.998	0.002
L50 Urticaria	0.000	0.998	0.002
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.998	0.001
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
C21.0 Anus, unspecified	0.000	0.998	0.002
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
J10 Influenza due to identified influenza virus	0.000	0.998	0.002
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
S09.9 Unspecified injury of head	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
J12 Viral pneumonia, not elsewhere classified	0.000	0.998	0.002
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
J11 Influenza, virus not identified	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
E55.0 Rickets, active	0.000	0.998	0.002
D48.5 Skin	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
Z51.5 Palliative care	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
L50.6 Contact urticaria	0.000	0.998	0.002
L50.5 Cholinergic urticaria	0.000	0.998	0.002
L50.4 Vibratory urticaria	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.000	0.998	0.002
L50.2 Urticaria due to cold and heat	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
M53.82 Other specified dorsopathies (Cervical region)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.998	0.001
L50.8 Other urticaria	0.000	0.998	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
H25.8 Other senile cataract	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.001	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.001
C25.9 Pancreas, unspecified	0.002	0.998	0.000
J12.8 Other viral pneumonia	0.000	0.998	0.001
J12.3 Human metapneumovirus pneumonia	0.000	0.998	0.001
J12.0 Adenoviral pneumonia	0.000	0.998	0.001
M89.8 Other specified disorders of bone	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.001	0.998	0.000
Z63.3 Absence of family member	0.001	0.998	0.000
Z63.2 Inadequate family support	0.001	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.998	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
J11.0 Influenza with pneumonia, virus not identified	0.000	0.998	0.001
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.998	0.002
D48.7 Other specified sites	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.998	0.001
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.998	0.001
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.000	0.998	0.001
O90.0 Disruption of Caesarean section wound	0.000	0.998	0.001
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
O02.1 Missed abortion	0.002	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.001	0.998	0.000
O22.8 Other venous complications in pregnancy	0.001	0.998	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.998	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.998	0.000
O22.1 Genital varices in pregnancy	0.001	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.001
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations