TreeWAS – Variant ID: rs2807278

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z83.5 Family history of eye and ear disorders	0.000	0.970	0.030
T36-T50 Poisoning by drugs, medicaments and biological substances	0.029	0.971	0.000
T43.2 Other and unspecified antidepressants	0.028	0.972	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.027	0.973	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.027	0.973	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.027	0.973	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.026	0.974	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.026	0.974	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.025	0.975	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.025	0.975	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.025	0.975	0.000
Z51.5 Palliative care	0.023	0.977	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.023	0.977	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.022	0.978	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.022	0.978	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.022	0.978	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.022	0.978	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.022	0.978	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.021	0.978	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.021	0.979	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.021	0.979	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.021	0.979	0.000
T45.2 Vitamins, not elsewhere classified	0.021	0.979	0.000
T45.0 Antiallergic and antiemetic drugs	0.021	0.979	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.021	0.979	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.021	0.979	0.000
T42.4 Benzodiazepines	0.021	0.979	0.000
T46.1 Calcium-channel blockers	0.021	0.979	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.021	0.979	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.020	0.980	0.000
T43.9 Psychotropic drug, unspecified	0.020	0.980	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.020	0.980	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.019	0.980	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.019	0.980	0.000
T46.7 Peripheral vasodilators	0.019	0.980	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.019	0.980	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.019	0.980	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.019	0.980	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.019	0.980	0.000
T42.3 Barbiturates	0.019	0.980	0.000
T42.2 Succinimides and oxazolidinediones	0.019	0.980	0.000
D13.1 Stomach	0.019	0.981	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.019	0.981	0.000
T45.8 Other primarily systemic and haematological agents	0.019	0.981	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.019	0.981	0.000
T45.6 Fibrinolysis-affecting drugs	0.019	0.981	0.000
T45.4 Iron and its compounds	0.019	0.981	0.000
T45.3 Enzymes, not elsewhere classified	0.019	0.981	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.019	0.981	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.018	0.982	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.018	0.982	0.000
T42.1 Iminostilbenes	0.018	0.982	0.000
T36 Poisoning by systemic antibiotics	0.018	0.982	0.000
R03.1 Nonspecific low blood-pressure reading	0.018	0.982	0.000
T38.9 Other and unspecified hormone antagonists	0.018	0.982	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.018	0.982	0.000
T38.7 Androgens and anabolic congeners	0.018	0.982	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.018	0.982	0.000
T38.5 Other oestrogens and progestogens	0.018	0.982	0.000
T38.4 Oral contraceptives	0.018	0.982	0.000
T38.2 Antithyroid drugs	0.018	0.982	0.000
T38.0 Glucocorticoids and synthetic analogues	0.018	0.982	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.018	0.982	0.000
T45.5 Anticoagulants	0.018	0.982	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.017	0.983	0.000
T40.5 Cocaine	0.017	0.983	0.000
T40.6 Other and unspecified narcotics	0.017	0.983	0.000
T47.0 Histamine H(2)-receptor antagonists	0.017	0.983	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.017	0.983	0.000
T47.6 Antidiarrhoeal drugs	0.017	0.983	0.000
I61 Intracerebral haemorrhage	0.017	0.983	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.017	0.983	0.000
T39.0 Salicylates	0.017	0.983	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.016	0.984	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.016	0.984	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.016	0.984	0.000
T47.7 Emetics	0.016	0.984	0.000
T47.5 Digestants	0.016	0.984	0.000
T47.4 Other laxatives	0.016	0.984	0.000
T47.3 Saline and osmotic laxatives	0.016	0.984	0.000
T47.2 Stimulant laxatives	0.016	0.984	0.000
T49.9 Topical agent, unspecified	0.016	0.984	0.000
T49.8 Other topical agents	0.016	0.984	0.000
T49.7 Dental drugs, topically applied	0.016	0.984	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.016	0.984	0.000
T49.5 Ophthalmological drugs and preparations	0.016	0.984	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.016	0.984	0.000
T49.3 Emollients, demulcents and protectants	0.016	0.984	0.000
T49.2 Local astringents and local detergents	0.016	0.984	0.000
T49.1 Antipruritics	0.016	0.984	0.000
T38.1 Thyroid hormones and substitutes	0.016	0.984	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.015	0.984	0.000
T48.5 Anti-common-cold drugs	0.015	0.984	0.000
T48.4 Expectorants	0.015	0.984	0.000
T48.3 Antitussives	0.015	0.984	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.015	0.984	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.015	0.984	0.000
T48.0 Oxytocic drugs	0.015	0.984	0.000
T40.4 Other synthetic narcotics	0.016	0.984	0.000
T43.6 Psychostimulants with abuse potential	0.015	0.984	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.015	0.984	0.000
T42.0 Hydantoin derivatives	0.015	0.984	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.015	0.985	0.000
T40.8 Lysergide [LSD]	0.015	0.985	0.000
T40.7 Cannabis (derivatives)	0.015	0.985	0.000
T40.3 Methadone	0.015	0.985	0.000
T40.1 Heroin	0.015	0.985	0.000
T40.0 Opium	0.015	0.985	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.015	0.985	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.015	0.985	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.015	0.985	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.015	0.985	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.015	0.985	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.015	0.985	0.000
T44.0 Anticholinesterase agents	0.015	0.985	0.000
T41.5 Therapeutic gases	0.015	0.985	0.000
T41.4 Anaesthetic, unspecified	0.015	0.985	0.000
T41.3 Local anaesthetics	0.015	0.985	0.000
T41.2 Other and unspecified general anaesthetics	0.015	0.985	0.000
T41.1 Intravenous anaesthetics	0.015	0.985	0.000
T41.0 Inhaled anaesthetics	0.015	0.985	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.015	0.985	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.015	0.985	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.015	0.985	0.000
T37.5 Antiviral drugs	0.015	0.985	0.000
T37.4 Anthelminthics	0.015	0.985	0.000
T37.3 Other antiprotozoal drugs	0.015	0.985	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.015	0.985	0.000
T37.1 Antimycobacterial drugs	0.015	0.985	0.000
T37.0 Sulphonamides	0.015	0.985	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.015	0.985	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.014	0.986	0.000
T50.4 Drugs affecting uric acid metabolism	0.014	0.986	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.014	0.986	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.014	0.986	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.014	0.986	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.014	0.986	0.000
T50.7 Analeptics and opioid receptor antagonists	0.014	0.986	0.000
T50.5 Appetite depressants	0.014	0.986	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.014	0.986	0.000
T50.1 Loop [high-ceiling] diuretics	0.014	0.986	0.000
T50.0 Mineralocorticoids and their antagonists	0.014	0.986	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
T39.4 Antirheumatics, not elsewhere classified	0.013	0.987	0.000
T39.2 Pyrazolone derivatives	0.013	0.987	0.000
T36.9 Systemic antibiotic, unspecified	0.013	0.987	0.000
T36.8 Other systemic antibiotics	0.013	0.987	0.000
T36.7 Antifungal antibiotics, systemically used	0.013	0.987	0.000
T36.6 Rifamycins	0.013	0.987	0.000
T36.5 Aminoglycosides	0.013	0.987	0.000
T36.4 Tetracyclines	0.013	0.987	0.000
T36.3 Macrolides	0.013	0.987	0.000
T36.2 Chloramphenicol group	0.013	0.987	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.013	0.987	0.000
T50.8 Diagnostic agents	0.013	0.987	0.000
F31 Bipolar affective disorder	0.013	0.987	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.013	0.987	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.013	0.987	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.012	0.988	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.012	0.988	0.000
I61.8 Other intracerebral haemorrhage	0.012	0.988	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.012	0.988	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.012	0.988	0.000
F31.7 Bipolar affective disorder, currently in remission	0.011	0.989	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.011	0.989	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.011	0.989	0.000
T39.1 4-Aminophenol derivatives	0.011	0.989	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
T36.0 Penicillins	0.010	0.989	0.000
T40.2 Other opioids	0.010	0.990	0.000
F31.8 Other bipolar affective disorders	0.010	0.990	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.010	0.990	0.000
Z63.4 Disappearance and death of family member	0.009	0.991	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.009	0.991	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.009	0.991	0.000
Q43 Other congenital malformations of intestine	0.008	0.992	0.000
O62.2 Other uterine inertia	0.008	0.992	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.008	0.992	0.000
Q39 Congenital malformations of oesophagus	0.008	0.992	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.008	0.992	0.000
Q38.7 Pharyngeal pouch	0.008	0.992	0.000
S91.3 Open wound of other parts of foot	0.008	0.992	0.000
Q45 Other congenital malformations of digestive system	0.008	0.992	0.000
F31.9 Bipolar affective disorder, unspecified	0.008	0.992	0.000
Q43.3 Congenital malformations of intestinal fixation	0.007	0.992	0.000
Q38.6 Other congenital malformations of mouth	0.007	0.993	0.000
S91 Open wound of ankle and foot	0.007	0.993	0.000
O62 Abnormalities of forces of labour	0.007	0.993	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.007	0.993	0.000
Q43.0 Meckel's diverticulum	0.007	0.993	0.000
Q39.4 Oesophageal web	0.007	0.993	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.007	0.993	0.000
Q44.6 Cystic disease of liver	0.007	0.993	0.000
Q40 Other congenital malformations of upper alimentary tract	0.007	0.993	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.007	0.993	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.007	0.993	0.000
S91.1 Open wound of toe(s) without damage to nail	0.007	0.993	0.000
S90-S99 Injuries to the ankle and foot	0.007	0.993	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.007	0.993	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.007	0.993	0.000
Q45.8 Other specified congenital malformations of digestive system	0.006	0.993	0.000
Q44.4 Choledochal cyst	0.006	0.993	0.000
Q38.8 Other congenital malformations of pharynx	0.006	0.993	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.006	0.993	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.006	0.993	0.000
Q38.3 Other congenital malformations of tongue	0.006	0.993	0.000
Q38.2 Macroglossia	0.006	0.993	0.000
Q38.1 Ankyloglossia	0.006	0.993	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.006	0.993	0.000
O62.3 Precipitate labour	0.006	0.994	0.000
Q43.7 Persistent cloaca	0.006	0.994	0.000
Q43.6 Congenital fistula of rectum and anus	0.006	0.994	0.000
Q43.5 Ectopic anus	0.006	0.994	0.000
Q43.4 Duplication of intestine	0.006	0.994	0.000
Q43.2 Other congenital functional disorders of colon	0.006	0.994	0.000
Q43.1 Hirschsprung's disease	0.006	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.006	0.994	0.000
N92.3 Ovulation bleeding	0.000	0.994	0.006
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
O62.9 Abnormality of forces of labour, unspecified	0.006	0.994	0.000
S99 Other and unspecified injuries of ankle and foot	0.006	0.994	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.006	0.994	0.000
Q44.7 Other congenital malformations of liver	0.006	0.994	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.006	0.994	0.000
Q44.2 Atresia of bile ducts	0.006	0.994	0.000
Q44.1 Other congenital malformations of gallbladder	0.006	0.994	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
Q39.8 Other congenital malformations of oesophagus	0.006	0.994	0.000
Q39.5 Congenital dilatation of oesophagus	0.006	0.994	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.006	0.994	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.006	0.994	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.006	0.994	0.000
Q39.0 Atresia of oesophagus without fistula	0.006	0.994	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.006	0.994	0.000
Q44.5 Other congenital malformations of bile ducts	0.006	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
Q67.6 Pectus excavatum	0.006	0.994	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.006	0.994	0.000
Q45.2 Congenital pancreatic cyst	0.006	0.994	0.000
Q45.1 Annular pancreas	0.006	0.994	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.006	0.994	0.000
Q39.6 Diverticulum of oesophagus	0.006	0.994	0.000
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
Q82 Other congenital malformations of skin	0.006	0.994	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.005	0.994	0.000
Q43.8 Other specified congenital malformations of intestine	0.005	0.994	0.000
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
Q76.0 Spina bifida occulta	0.005	0.994	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.994	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.994	0.000
S91.7 Multiple open wounds of ankle and foot	0.005	0.994	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.005	0.995	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.005	0.995	0.000
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
O62.8 Other abnormalities of forces of labour	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
Q89.2 Congenital malformations of other endocrine glands	0.005	0.995	0.000
S91.2 Open wound of toe(s) with damage to nail	0.005	0.995	0.000
S99.9 Unspecified injury of ankle and foot	0.005	0.995	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
S90 Superficial injury of ankle and foot	0.005	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.995	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q40.1 Congenital hiatus hernia	0.005	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.995	0.000
S97 Crushing injury of ankle and foot	0.005	0.995	0.000
S99.8 Other specified injuries of ankle and foot	0.005	0.995	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.005	0.995	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.005	0.995	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.005	0.995	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.005	0.995	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.005	0.995	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.005	0.995	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.005	0.995	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.005	0.995	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.005	0.995	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.005	0.995	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.005	0.995	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.005	0.995	0.000
S95 Injury of blood vessels at ankle and foot level	0.005	0.995	0.000
S94 Injury of nerves at ankle and foot level	0.005	0.995	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.005	0.995	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.005	0.995	0.000
Q82.5 Congenital nonneoplastic naevus	0.005	0.995	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
Q67.8 Other congenital deformities of chest	0.005	0.995	0.000
Q67.7 Pectus carinatum	0.005	0.995	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.005	0.995	0.000
Q67.3 Plagiocephaly	0.005	0.995	0.000
Q67.2 Dolichocephaly	0.005	0.995	0.000
Q67.1 Compression facies	0.005	0.995	0.000
Q67.0 Facial asymmetry	0.005	0.995	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q82.2 Mastocytosis	0.005	0.995	0.000
Q76.5 Cervical rib	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.005	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.005	0.995	0.000
Q76.7 Congenital malformation of sternum	0.005	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.005	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.005	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.005	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.995	0.000
S99.7 Multiple injuries of ankle and foot	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
S92 Fracture of foot, except ankle	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.004	0.995	0.000
Q66.5 Congenital pes planus	0.004	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.995	0.000
Q66.1 Talipes calcaneovarus	0.004	0.995	0.000
Q82.0 Hereditary lymphoedema	0.004	0.995	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.004	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.001
D13.7 Endocrine pancreas	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
I47 Paroxysmal tachycardia	0.004	0.996	0.000
Q82.8 Other specified congenital malformations of skin	0.004	0.996	0.000
S91.0 Open wound of ankle	0.004	0.996	0.000
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
Q82.9 Congenital malformation of skin, unspecified	0.004	0.996	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.004	0.996	0.000
Q82.3 Incontinentia pigmenti	0.004	0.996	0.000
Q82.1 Xeroderma pigmentosum	0.004	0.996	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
D13.4 Liver	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.4 Renal dysplasia	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
S97.0 Crushing injury of ankle	0.004	0.996	0.000
M65.34 Trigger finger-Hand	0.004	0.996	0.000
I47.1 Supraventricular tachycardia	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.996	0.000
Q78.6 Multiple congenital exostoses	0.004	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.996	0.000
Q78.4 Enchondromatosis	0.004	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.996	0.000
Q78.2 Osteopetrosis	0.004	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.996	0.000
O62.0 Primary inadequate contractions	0.004	0.996	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
I47.0 Reentry ventricular arrhythmia	0.004	0.996	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.004	0.996	0.000
Q62.5 Duplication of ureter	0.004	0.996	0.000
K65.9 Peritonitis, unspecified	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.004	0.996	0.000
S94.8 Injury of other nerves at ankle and foot level	0.004	0.996	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.004	0.996	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.004	0.996	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.004	0.996	0.000
S94.1 Injury of medial plantar nerve	0.004	0.996	0.000
S94.0 Injury of lateral plantar nerve	0.004	0.996	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.004	0.996	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.004	0.996	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.004	0.996	0.000
S95.2 Injury of dorsal vein of foot	0.004	0.996	0.000
S95.1 Injury of plantar artery of foot	0.004	0.996	0.000
S95.0 Injury of dorsal artery of foot	0.004	0.996	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.004	0.996	0.000
S98.3 Traumatic amputation of other parts of foot	0.004	0.996	0.000
S98.2 Traumatic amputation of two or more toes	0.004	0.996	0.000
S98.1 Traumatic amputation of one toe	0.004	0.996	0.000
S98.0 Traumatic amputation of foot at ankle level	0.004	0.996	0.000
D13.5 Extrahepatic bile ducts	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.996	0.004
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.004	0.996	0.000
Q69.2 Accessory toe(s)	0.004	0.996	0.000
Q69.1 Accessory thumb(s)	0.004	0.996	0.000
Q69.0 Accessory finger(s)	0.004	0.996	0.000
Q70.9 Syndactyly, unspecified	0.004	0.996	0.000
Q70.4 Polysyndactyly	0.004	0.996	0.000
Q70.3 Webbed toes	0.004	0.996	0.000
Q70.2 Fused toes	0.004	0.996	0.000
Q70.1 Webbed fingers	0.004	0.996	0.000
Q70.0 Fused fingers	0.004	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.996	0.000
Q71.6 Lobster-claw hand	0.004	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.996	0.000
Q72.7 Split foot	0.004	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.996	0.000
Q75.3 Macrocephaly	0.004	0.996	0.000
Q75.2 Hypertelorism	0.004	0.996	0.000
Q75.1 Craniofacial dysostosis	0.004	0.996	0.000
Q75.0 Craniosynostosis	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.4 Achondroplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
S90.1 Contusion of toe(s) without damage to nail	0.004	0.996	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
D13.6 Pancreas	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
S90.0 Contusion of ankle	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
S93.1 Dislocation of toe(s)	0.004	0.996	0.000
Q12.0 Congenital cataract	0.000	0.996	0.003
H35.7 Separation of retinal layers	0.004	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations