TreeWAS – Variant ID: rs2819348

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.073	0.927	0.000
I10-I15 Hypertensive diseases	0.025	0.975	0.000
S43.0 Dislocation of shoulder joint	0.023	0.977	0.000
D12.3 Transverse colon	0.021	0.979	0.000
I13 Hypertensive heart and renal disease	0.021	0.979	0.000
I15 Secondary hypertension	0.019	0.981	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.017	0.983	0.000
I15.9 Seconday hypertension, unspecified	0.017	0.983	0.000
I11 Hypertensive heart disease	0.016	0.984	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.016	0.984	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.015	0.985	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.015	0.985	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.015	0.985	0.000
I15.8 Other secondary hypertension	0.014	0.986	0.000
I15.2 Hypertension secondary to endocrine disorders	0.014	0.986	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.013	0.987	0.000
S43.4 Sprain and strain of shoulder joint	0.013	0.987	0.000
S00.7 Multiple superficial injuries of head	0.012	0.988	0.000
I15.1 Hypertension secondary to other renal disorders	0.012	0.988	0.000
I15.0 Renovascular hypertension	0.012	0.988	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.012	0.988	0.000
S00.8 Superficial injury of other parts of head	0.012	0.988	0.000
S00 Superficial injury of head	0.011	0.989	0.000
S00.9 Superficial injury of head, part unspecified	0.011	0.989	0.000
I25.1 Atherosclerotic heart disease	0.011	0.989	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.011	0.989	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.011	0.989	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.011	0.989	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.011	0.989	0.000
S43.2 Dislocation of sternoclavicular joint	0.011	0.989	0.000
I12 Hypertensive renal disease	0.011	0.989	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.010	0.990	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.010	0.990	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.991	0.009
S00.5 Superficial injury of lip and oral cavity	0.009	0.991	0.000
S40-S49 Injuries to the shoulder and upper arm	0.008	0.992	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.008	0.992	0.000
S00.4 Superficial injury of ear	0.008	0.992	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.008	0.992	0.000
S42.40 Fracture of lower end of humerus (closed)	0.008	0.992	0.000
S00.1 Contusion of eyelid and periocular area	0.008	0.992	0.000
S43.1 Dislocation of acromioclavicular joint	0.008	0.992	0.000
I21 Acute myocardial infarction	0.008	0.992	0.000
S41 Open wound of shoulder and upper arm	0.007	0.992	0.000
S42.4 Fracture of lower end of humerus	0.007	0.993	0.000
I20 Angina pectoris	0.007	0.993	0.000
I20.9 Angina pectoris, unspecified	0.007	0.993	0.000
I12.9 Hypertensive renal disease without renal failure	0.007	0.993	0.000
H54.7 Unspecified visual loss	0.000	0.993	0.007
S41.0 Open wound of shoulder	0.007	0.993	0.000
S42 Fracture of shoulder and upper arm	0.007	0.993	0.000
I20.8 Other forms of angina pectoris	0.007	0.993	0.000
I21.4 Acute subendocardial myocardial infarction	0.007	0.993	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.007	0.993	0.000
S40 Superficial injury of shoulder and upper arm	0.007	0.993	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.007	0.993	0.000
S00.0 Superficial injury of scalp	0.007	0.993	0.000
D25.1 Intramural leiomyoma of uterus	0.007	0.993	0.000
I20-I25 Ischaemic heart diseases	0.007	0.993	0.000
I20.0 Unstable angina	0.006	0.994	0.000
I25 Chronic ischaemic heart disease	0.006	0.994	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.006	0.994	0.000
S48 Traumatic amputation of shoulder and upper arm	0.006	0.994	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.006	0.994	0.000
S44 Injury of nerves at shoulder and upper arm level	0.006	0.994	0.000
S47 Crushing injury of shoulder and upper arm	0.006	0.994	0.000
S00.3 Superficial injury of nose	0.006	0.994	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.006	0.994	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.006	0.994	0.000
S42.41 Fracture of lower end of humerus (open)	0.006	0.994	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.005	0.994	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.005	0.994	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.005	0.994	0.000
S41.1 Open wound of upper arm	0.005	0.995	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
S42.1 Fracture of scapula	0.005	0.995	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.005	0.995	0.000
S40.0 Contusion of shoulder and upper arm	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.005	0.995	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.005	0.995	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.005	0.995	0.000
Q23.3 Congenital mitral insufficiency	0.005	0.995	0.000
I23 Certain current complications following acute myocardial infarction	0.005	0.995	0.000
I25.6 Silent myocardial ischaemia	0.005	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
S42.2 Fracture of upper end of humerus	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
S46.3 Injury of muscle and tendon of triceps	0.005	0.995	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.005	0.995	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.005	0.995	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.005	0.995	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.005	0.995	0.000
S44.4 Injury of musculocutaneous nerve	0.005	0.995	0.000
S44.3 Injury of axillary nerve	0.005	0.995	0.000
S44.2 Injury of radial nerve at upper arm level	0.005	0.995	0.000
S44.1 Injury of median nerve at upper arm level	0.005	0.995	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.005	0.995	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.005	0.995	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.005	0.995	0.000
S45.2 Injury of axillary or brachial vein	0.005	0.995	0.000
S45.1 Injury of brachial artery	0.005	0.995	0.000
S45.0 Injury of axillary artery	0.005	0.995	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.005	0.995	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.005	0.995	0.000
S48.0 Traumatic amputation at shoulder joint	0.005	0.995	0.000
S42.0 Fracture of clavicle	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.005	0.995	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.005	0.995	0.000
I25.3 Aneurysm of heart	0.005	0.995	0.000
R25.2 Cramp and spasm	0.005	0.995	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.004	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.995	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.004	0.995	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.004	0.996	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.004	0.996	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.996	0.004
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.004	0.996	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.004	0.996	0.000
I25.2 Old myocardial infarction	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.004	0.996	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.004	0.996	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
C77.8 Lymph nodes of multiple regions	0.004	0.996	0.000
I25.4 Coronary artery aneurysm	0.004	0.996	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
I22 Subsequent myocardial infarction	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q40.1 Congenital hiatus hernia	0.004	0.996	0.000
S42.11 Fracture of scapula (open)	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
I20.1 Angina pectoris with documented spasm	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.004	0.996	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.004	0.996	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.004	0.996	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
E11.9 Without complications	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.004	0.996	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.003	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
S42.21 Fracture of upper end of humerus (open)	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.996	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
S42.01 Fracture of clavicle (open)	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.004	0.996	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.996	0.000
Q25.0 Patent ductus arteriosus	0.003	0.996	0.000
K01.1 Impacted teeth	0.000	0.996	0.004
Q51 Congenital malformations of uterus and cervix	0.003	0.996	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
H26.8 Other specified cataract	0.000	0.997	0.003
L60.8 Other nail disorders	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
I25.5 Ischaemic cardiomyopathy	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
I23.8 Other current complications following acute myocardial infarction	0.003	0.997	0.000
Q52.5 Fusion of labia	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
L60.0 Ingrowing nail	0.000	0.997	0.003
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
G25.3 Myoclonus	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
H26.4 After-cataract	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
L60 Nail disorders	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.997	0.003
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
T85.2 Mechanical complication of intraocular lens	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
D68 Other coagulation defects	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
L43.8 Other lichen planus	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.997	0.003
I22.9 Subsequent myocardial infarction of unspecified site	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.997	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.997	0.000
Q45.1 Annular pancreas	0.002	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.003	0.997	0.000
Q24.0 Dextrocardia	0.002	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.997	0.000
Q84 Other congenital malformations of integument	0.002	0.997	0.000
Q81 Epidermolysis bullosa	0.002	0.997	0.000
Q80 Congenital ichthyosis	0.002	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
G25.2 Other specified forms of tremor	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.002	0.997	0.000
Q44.6 Cystic disease of liver	0.002	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.997	0.000
Q33 Congenital malformations of lung	0.002	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.997	0.000
Q30 Congenital malformations of nose	0.002	0.997	0.000
Q77.4 Achondroplasia	0.002	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.997	0.000
Q24.5 Malformation of coronary vessels	0.002	0.997	0.000
Q31 Congenital malformations of larynx	0.002	0.997	0.000
Q24.6 Congenital heart block	0.002	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.997	0.000
Q65 Congenital deformities of hip	0.002	0.997	0.000
L60.9 Nail disorder, unspecified	0.000	0.997	0.002
L60.3 Nail dystrophy	0.000	0.997	0.002
L60.2 Onychogryphosis	0.000	0.997	0.002
L73.9 Follicular disorder, unspecified	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.997	0.000
Q11.1 Other anophthalmos	0.002	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
L60.5 Yellow nail syndrome	0.000	0.998	0.002
L60.4 Beau's lines	0.000	0.998	0.002
L60.1 Onycholysis	0.000	0.998	0.002
Q35.9 Cleft palate, unspecified	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q15.0 Congenital glaucoma	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
L43 Lichen planus	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
K52.3 Indeterminate colitis	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.002	0.998	0.000
Q35.7 Cleft uvula	0.002	0.998	0.000
Q35.6 Cleft palate, medial	0.002	0.998	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.002	0.998	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.3 Cleft soft palate	0.002	0.998	0.000
Q35.2 (Cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.1 Cleft hard palate	0.002	0.998	0.000
Q35.0 (Cleft hard palate, bilateral)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations