TreeWAS – Variant ID: rs2825388

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.147	0.853	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.145	0.855	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.144	0.856	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.140	0.860	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.122	0.878	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.120	0.880	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.116	0.884	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.110	0.890	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.082	0.918	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.076	0.924	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.029	0.971	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.027	0.973	0.000
N83.1 Corpus luteum cyst	0.000	0.976	0.024
K55.2 Angiodysplasia of colon	0.000	0.984	0.016
G51.0 Bell's palsy	0.000	0.986	0.014
E27 Other disorders of adrenal gland	0.013	0.987	0.000
G51 Facial nerve disorders	0.000	0.988	0.012
G51.8 Other disorders of facial nerve	0.000	0.989	0.011
G51.3 Clonic hemifacial spasm	0.000	0.989	0.011
E27.3 Drug-induced adrenocortical insufficiency	0.011	0.989	0.000
E27.5 Adrenomedullary hyperfunction	0.009	0.990	0.000
E27.0 Other adrenocortical overactivity	0.009	0.990	0.000
E27.9 Disorder of adrenal gland, unspecified	0.009	0.991	0.000
G51.9 Disorder of facial nerve, unspecified	0.000	0.991	0.009
G51.4 Facial myokymia	0.000	0.991	0.009
G51.2 Melkersson's syndrome	0.000	0.991	0.009
G51.1 Geniculate ganglionitis	0.000	0.991	0.009
E27.8 Other specified disorders of adrenal gland	0.009	0.991	0.000
E27.2 Addisonian crisis	0.009	0.991	0.000
M50.2 Other cervical disk displacement	0.000	0.993	0.007
D24 Benign neoplasm of breast	0.007	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
E34 Other endocrine disorders	0.007	0.993	0.000
F99 Mental disorder, not otherwise specified	0.000	0.993	0.007
Q28.2 Arteriovenous malformation of cerebral vessels	0.007	0.993	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
E34.0 Carcinoid syndrome	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.006	0.994	0.000
Q28 Other congenital malformations of circulatory system	0.006	0.994	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
E24 Cushing's syndrome	0.006	0.994	0.000
E28 Ovarian dysfunction	0.006	0.994	0.000
J06.9 Acute upper respiratory infection, unspecified	0.006	0.994	0.000
S51.0 Open wound of elbow	0.000	0.994	0.006
E25 Adrenogenital disorders	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.005	0.994	0.000
E22 Hyperfunction of pituitary gland	0.005	0.994	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
Q25.1 Coarctation of aorta	0.005	0.995	0.000
Q18 Other congenital malformations of face and neck	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.005	0.995	0.000
E34.4 Constitutional tall stature	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.000
Q53.1 Undescended testicle, unilateral	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q25.3 Stenosis of aorta	0.005	0.995	0.000
Q53 Undescended testicle	0.005	0.995	0.000
Q17 Other congenital malformations of ear	0.005	0.995	0.000
Q80-Q89 Other congenital malformations	0.005	0.995	0.000
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
E24.9 Cushing's syndrome, unspecified	0.005	0.995	0.000
E24.8 Other Cushing's syndrome	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
E28.2 Polycystic ovarian syndrome	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
C92.0 Acute myeloid leukaemia	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
R01.1 Cardiac murmur, unspecified	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.005	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.005	0.995	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.995	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.995	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
Q23.3 Congenital mitral insufficiency	0.005	0.995	0.000
Q62.5 Duplication of ureter	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q17.5 Prominent ear	0.004	0.995	0.000
Q24.5 Malformation of coronary vessels	0.004	0.995	0.000
Q12 Congenital lens malformations	0.004	0.995	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
K55 Vascular disorders of intestine	0.000	0.996	0.004
E23.0 Hypopituitarism	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
E22.8 Other hyperfunction of pituitary gland	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q85.1 Tuberous sclerosis	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.004	0.996	0.000
Q18.8 Other specified congenital malformations of face and neck	0.004	0.996	0.000
Q18.7 Microcheilia	0.004	0.996	0.000
Q18.6 Macrocheilia	0.004	0.996	0.000
Q18.5 Microstomia	0.004	0.996	0.000
Q18.4 Macrostomia	0.004	0.996	0.000
Q18.3 Webbing of neck	0.004	0.996	0.000
Q18.2 Other branchial cleft malformations	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
M22.4 Chondromalacia patellae	0.000	0.996	0.004
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
M50.3 Other cervical disk degeneration	0.000	0.996	0.004
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Q10.0 Congenital ptosis	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
Q44.7 Other congenital malformations of liver	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
D52.9 Folate deficiency anaemia, unspecified	0.004	0.996	0.000
Q53.9 Undescended testicle, unspecified	0.004	0.996	0.000
Q53.0 Ectopic testis	0.004	0.996	0.000
Q17.9 Congenital malformation of ear, unspecified	0.004	0.996	0.000
Q17.8 Other specified congenital malformations of ear	0.004	0.996	0.000
Q17.4 Misplaced ear	0.004	0.996	0.000
Q17.3 Other misshapen ear	0.004	0.996	0.000
Q17.2 Microtia	0.004	0.996	0.000
Q17.1 Macrotia	0.004	0.996	0.000
Q17.0 Accessory auricle	0.004	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q55.6 Other congenital malformations of penis	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.996	0.004
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
E26 Hyperaldosteronism	0.003	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.003	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.996	0.000
Q54.1 Hypospadias, penile	0.004	0.996	0.000
Q12.0 Congenital cataract	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.996	0.000
M50 Cervical disk disorders	0.000	0.996	0.004
Q44.4 Choledochal cyst	0.003	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.996	0.000
Q44.2 Atresia of bile ducts	0.003	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q10.7 Congenital malformation of orbit	0.003	0.996	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.996	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.996	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.996	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.996	0.000
Q10.2 Congenital entropion	0.003	0.996	0.000
Q10.1 Congenital ectropion	0.003	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.996	0.000
Q33 Congenital malformations of lung	0.003	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.996	0.000
Q30 Congenital malformations of nose	0.003	0.996	0.000
Q60.6 Potter's syndrome	0.003	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.996	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.996	0.000
Q01 Encephalocele	0.003	0.996	0.000
Q00 Anencephaly and similar malformations	0.003	0.996	0.000
Q02 Microcephaly	0.003	0.996	0.000
Q12.9 Congenital lens malformation, unspecified	0.003	0.996	0.000
Q12.8 Other congenital lens malformations	0.003	0.996	0.000
Q12.4 Spherophakia	0.003	0.996	0.000
Q12.3 Congenital aphakia	0.003	0.996	0.000
Q12.2 Coloboma of lens	0.003	0.996	0.000
Q12.1 Congenital displaced lens	0.003	0.996	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.996	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
M50.9 Cervical disk disorder, unspecified	0.000	0.997	0.003
Q90 Down's syndrome	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.003	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q13.5 Blue sclera	0.003	0.997	0.000
Q13.4 Other congenital corneal malformations	0.003	0.997	0.000
Q13.3 Congenital corneal opacity	0.003	0.997	0.000
Q13.2 Other congenital malformations of iris	0.003	0.997	0.000
Q13.1 Absence of iris	0.003	0.997	0.000
Q13.0 Coloboma of iris	0.003	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.003	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.003	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.003	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.003	0.997	0.000
Q16.2 Absence of eustachian tube	0.003	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.003	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
J06.0 Acute laryngopharyngitis	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
M48.0 Spinal stenosis	0.000	0.997	0.003
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.003	0.997	0.000
Q11.2 Microphthalmos	0.003	0.997	0.000
Q11.0 Cystic eyeball	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.997	0.003
Q15.9 Congenital malformation of eye, unspecified	0.003	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q31.0 Web of larynx	0.003	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.997	0.003
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.997	0.003
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.997	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.3 Congenital malformation of choroid	0.003	0.997	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.997	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.003	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.003	0.997	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.997	0.003
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.003	0.997	0.000
Q31.8 Other congenital malformations of larynx	0.003	0.997	0.000
Q31.5 Congenital laryngomalacia	0.003	0.997	0.000
Q31.4 Congenital laryngeal stridor	0.003	0.997	0.000
Q31.3 Laryngocele	0.003	0.997	0.000
Q31.2 Laryngeal hypoplasia	0.003	0.997	0.000
Q31.1 Congenital subglottic stenosis	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.997	0.003
M48.06 Spinal stenosis (Lumbar region)	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.997	0.000
F99-F99 Unspecified mental disorder	0.000	0.997	0.003
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.002	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.997	0.003
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.003
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
K55.8 Other vascular disorders of intestine	0.000	0.997	0.003
Q30.9 Congenital malformation of nose, unspecified	0.003	0.997	0.000
Q30.8 Other congenital malformations of nose	0.003	0.997	0.000
Q30.2 Fissured, notched and cleft nose	0.003	0.997	0.000
Q30.1 Agenesis and underdevelopment of nose	0.003	0.997	0.000
Q30.0 Choanal atresia	0.003	0.997	0.000
Q32.4 Other congenital malformations of bronchus	0.003	0.997	0.000
Q32.3 Congenital stenosis of bronchus	0.003	0.997	0.000
Q32.2 Congenital bronchomalacia	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations