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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28359524
log Bayes Factor = 12.4863
Chromosome 8   position 18,076,854  (GRCh37) Explore rs28359524 on Ensembl!
Variant rs28359524 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
N20-N23 Urolithiasis
0.990 0.010 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.989 0.011 0.000
C79 Secondary malignant neoplasm of other sites
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
N20 Calculus of kidney and ureter
0.977 0.023 0.000
N30-N39 Other diseases of urinary system
0.973 0.027 0.000
N40-N51 Diseases of male genital organs
0.972 0.028 0.000
M13 Other arthritis
0.969 0.031 0.000
H90-H95 Other disorders of ear
0.961 0.039 0.000
M50-M54 Other dorsopathies
0.961 0.039 0.000
M13.9 Arthritis, unspecified
0.957 0.043 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.955 0.045 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.949 0.051 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.946 0.054 0.000
N72 Inflammatory disease of cervix uteri
0.944 0.056 0.000
H91 Other hearing loss
0.943 0.057 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.942 0.058 0.000
C51-C58 Malignant neoplasms of female genital organs
0.932 0.068 0.000
H91.9 Hearing loss, unspecified
0.931 0.069 0.000
N20.1 Calculus of ureter
0.930 0.070 0.000
N48 Other disorders of penis
0.930 0.070 0.000
N35 Urethral stricture
0.917 0.083 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.915 0.085 0.000
N30 Cystitis
0.914 0.086 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.911 0.089 0.000
C78.0 Secondary malignant neoplasm of lung
0.908 0.092 0.000
G20-G26 Extrapyramidal and movement disorders
0.907 0.093 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.906 0.094 0.000
C15-C26 Malignant neoplasms of digestive organs
0.904 0.096 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.904 0.096 0.000
G35 Multiple sclerosis
0.902 0.098 0.000
H80-H83 Diseases of inner ear
0.900 0.100 0.000
C44 Other malignant neoplasms of skin
0.895 0.105 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.893 0.107 0.000
M51 Other intervertebral disk disorders
0.892 0.108 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.889 0.111 0.000
C64-C68 Malignant neoplasms of urinary tract
0.887 0.113 0.000
Chapter V Mental and behavioural disorders
0.886 0.114 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.879 0.121 0.000
N20.0 Calculus of kidney
0.877 0.123 0.000
N35.9 Urethral stricture, unspecified
0.877 0.123 0.000
M40-M43 Deforming dorsopathies
0.876 0.124 0.000
S90-S99 Injuries to the ankle and foot
0.873 0.127 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.872 0.128 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.864 0.136 0.000
M54 Dorsalgia
0.863 0.137 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.858 0.142 0.000
M51.2 Other specified intervertebral disk displacement
0.852 0.148 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.851 0.149 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.850 0.150 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.850 0.150 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.849 0.151 0.000
N00-N08 Glomerular diseases
0.845 0.155 0.000
Y95 Nosocomial condition
0.842 0.158 0.000
G20 Parkinson's disease
0.840 0.160 0.000
N23 Unspecified renal colic
0.837 0.163 0.000
M54.3 Sciatica
0.835 0.165 0.000
M05 Seropositive rheumatoid arthritis
0.834 0.166 0.000
C80 Malignant neoplasm without specification of site
0.832 0.168 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.832 0.168 0.000
N71 Inflammatory disease of uterus, except cervix
0.831 0.169 0.000
S50-S59 Injuries to the elbow and forearm
0.831 0.169 0.000
N32 Other disorders of bladder
0.831 0.169 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.831 0.169 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.830 0.170 0.000
T81 Complications of procedures, not elsewhere classified
0.825 0.175 0.000
N30.2 Other chronic cystitis
0.823 0.177 0.000
N42 Other disorders of prostate
0.823 0.177 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.821 0.179 0.000
C44.0 Skin of lip
0.819 0.181 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.818 0.181 0.000
Y45.0 Opioids and related analgesics
0.815 0.185 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.815 0.185 0.000
N48.2 Other inflammatory disorders of penis
0.815 0.185 0.000
C43 Malignant melanoma of skin
0.813 0.187 0.000
C54 Malignant neoplasm of corpus uteri
0.812 0.188 0.000
N30.9 Cystitis, unspecified
0.811 0.189 0.000
C34 Malignant neoplasm of bronchus and lung
0.810 0.190 0.000
E65-E68 Obesity and other hyperalimentation
0.810 0.190 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.806 0.194 0.000
N20.9 Urinary calculus, unspecified
0.805 0.195 0.000
N48.1 Balanoposthitis
0.803 0.197 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.799 0.201 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.799 0.201 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.798 0.202 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.202 0.000
N25-N29 Other disorders of kidney and ureter
0.797 0.203 0.000
C44.2 Skin of ear and external auricular canal
0.797 0.203 0.000
M54.39 Sciatica (Site unspecified)
0.797 0.203 0.000
C15 Malignant neoplasm of oesophagus
0.796 0.204 0.000
H81 Disorders of vestibular function
0.795 0.205 0.000
M65-M68 Disorders of synovium and tendon
0.794 0.206 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.793 0.207 0.000
W20-W49 Exposure to inanimate mechanical forces
0.790 0.210 0.000
S90 Superficial injury of ankle and foot
0.790 0.210 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.789 0.211 0.000
C56 Malignant neoplasm of ovary
0.789 0.211 0.000
C79.2 Secondary malignant neoplasm of skin
0.787 0.213 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.786 0.214 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.786 0.214 0.000
Y52 Agents primarily affecting the cardiovascular system
0.785 0.215 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
G40-G47 Episodic and paroxysmal disorders
0.783 0.217 0.000
E66 Obesity
0.782 0.218 0.000
M06 Other rheumatoid arthritis
0.781 0.219 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.781 0.219 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.780 0.220 0.000
H83 Other diseases of inner ear
0.778 0.221 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.778 0.222 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.777 0.223 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.776 0.224 0.000
G37 Other demyelinating diseases of central nervous system
0.775 0.225 0.000
N48.8 Other specified disorders of penis
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.773 0.226 0.000
G90-G99 Other disorders of the nervous system
0.767 0.233 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.765 0.235 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.765 0.235 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.765 0.235 0.000
N32.9 Bladder disorder, unspecified
0.763 0.236 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
N73 Other female pelvic inflammatory diseases
0.761 0.239 0.000
N70 Salpingitis and oophoritis
0.760 0.240 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.757 0.243 0.000
N40 Hyperplasia of prostate
0.757 0.243 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.756 0.243 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
Y44 Agents primarily affecting blood constituents
0.755 0.245 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.754 0.246 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.753 0.247 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.752 0.247 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.752 0.248 0.000
M91-M94 Chondropathies
0.751 0.249 0.000
S40-S49 Injuries to the shoulder and upper arm
0.750 0.250 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.750 0.250 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
X20-X29 Contact with venomous animals and plants
0.747 0.253 0.000
G47 Sleep disorders
0.746 0.254 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.745 0.255 0.000
H93 Other disorders of ear, not elsewhere classified
0.745 0.255 0.000
M41 Scoliosis
0.742 0.257 0.000
S10-S19 Injuries to the neck
0.740 0.260 0.000
N76 Other inflammation of vagina and vulva
0.740 0.260 0.000
S80-S89 Injuries to the knee and lower leg
0.738 0.262 0.000
C67 Malignant neoplasm of bladder
0.737 0.263 0.000
T39.1 4-Aminophenol derivatives
0.736 0.264 0.000
N99-N99 Other disorders of the genitourinary system
0.735 0.265 0.000
N20.2 Calculus of kidney with calculus of ureter
0.735 0.265 0.000
M70-M79 Other soft tissue disorders
0.735 0.265 0.000
L85 Other epidermal thickening
0.734 0.266 0.000
C53 Malignant neoplasm of cervix uteri
0.733 0.266 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.732 0.268 0.000
N30.3 Trigonitis
0.731 0.269 0.000
M13.0 Polyarthritis, unspecified
0.730 0.270 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.730 0.270 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.726 0.273 0.000
C54.1 Endometrium
0.726 0.274 0.000
S51 Open wound of forearm
0.726 0.274 0.000
G81 Hemiplegia
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.724 0.275 0.000
Y43 Primarily systemic agents
0.724 0.276 0.000
Y40 Systemic antibiotics
0.723 0.277 0.000
L91 Hypertrophic disorders of skin
0.722 0.278 0.000
N03 Chronic nephritic syndrome
0.721 0.279 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.721 0.279 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.720 0.280 0.000
V10-V19 Pedal cyclist injured in transport accident
0.720 0.280 0.000
M80-M85 Disorders of bone density and structure
0.720 0.280 0.000
E66.8 Other obesity
0.719 0.281 0.000
C44.3 Skin of other and unspecified parts of face
0.719 0.281 0.000
N42.1 Congestion and haemorrhage of prostate
0.718 0.282 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.717 0.283 0.000
C34.0 Main bronchus
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M20-M25 Other joint disorders
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M43 Other deforming dorsopathies
0.714 0.286 0.000
D80-D89 Certain disorders involving the immune mechanism
0.714 0.286 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
E66.9 Obesity, unspecified
0.711 0.289 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.710 0.290 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.709 0.291 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.709 0.291 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.709 0.291 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.709 0.291 0.000
C79.6 Secondary malignant neoplasm of ovary
0.709 0.291 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.709 0.291 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.709 0.291 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.709 0.291 0.000
N45 Orchitis and epididymitis
0.708 0.292 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.292 0.000
C01 Malignant neoplasm of base of tongue
0.707 0.293 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.294 0.000
M12 Other specific arthropathies
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.294 0.000
M08 Juvenile arthritis
0.706 0.294 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.705 0.295 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.703 0.296 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.701 0.299 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
N21 Calculus of lower urinary tract
0.701 0.299 0.000
M54.37 Sciatica (Lumbosacral region)
0.701 0.299 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.701 0.299 0.000
H81.0 Meniere's disease
0.700 0.300 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.700 0.300 0.000
Y57 Other and unspecified drugs and medicaments
0.699 0.301 0.000
N48.6 Balanitis xerotica obliterans
0.698 0.302 0.000
N37 Urethral disorders in diseases classified elsewhere
0.697 0.303 0.000
N34 Urethritis and urethral syndrome
0.697 0.303 0.000
N33 Bladder disorders in diseases classified elsewhere
0.697 0.303 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.697 0.303 0.000
N46 Male infertility
0.697 0.303 0.000
N44 Torsion of testis
0.697 0.303 0.000
C44.4 Skin of scalp and neck
0.696 0.304 0.000
M13.8 Other specified arthritis
0.695 0.305 0.000
M13.1 Monoarthritis, not elsewhere classified
0.695 0.305 0.000
C44.6 Skin of upper limb, including shoulder
0.694 0.306 0.000
G70-G73 Diseases of myoneural junction and muscle
0.693 0.307 0.000
M13.94 Arthritis, unspecified (Hand)
0.693 0.307 0.000
M07 Psoriatic and enteropathic arthropathies
0.693 0.307 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.692 0.308 0.000
D86 Sarcoidosis
0.692 0.308 0.000
T93 Sequelae of injuries of lower limb
0.692 0.308 0.000
H83.0 Labyrinthitis
0.691 0.309 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.690 0.310 0.000
T90 Sequelae of injuries of head
0.690 0.310 0.000
C20 Malignant neoplasm of rectum
0.690 0.310 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.689 0.311 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.689 0.311 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.689 0.311 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.688 0.311 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.688 0.312 0.000
C15.9 Oesophagus, unspecified
0.688 0.312 0.000
C21 Malignant neoplasm of anus and anal canal
0.688 0.312 0.000
H92 Otalgia and effusion of ear
0.688 0.312 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.687 0.313 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.687 0.313 0.000
C18 Malignant neoplasm of colon
0.687 0.313 0.000
T51 Toxic effect of alcohol
0.687 0.313 0.000
M13.98 Arthritis, unspecified (Other)
0.686 0.314 0.000
M13.93 Arthritis, unspecified (Forearm)
0.686 0.314 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
T86 Failure and rejection of transplanted organs and tissues
0.685 0.314 0.000
N48.0 Leukoplakia of penis
0.685 0.315 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.684 0.316 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.684 0.316 0.000
G82 Paraplegia and tetraplegia
0.682 0.318 0.000
L57.0 Actinic keratosis
0.682 0.318 0.000
S50 Superficial injury of forearm
0.681 0.318 0.000
G36 Other acute disseminated demyelination
0.680 0.319 0.000
N36 Other disorders of urethra
0.680 0.320 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
H90 Conductive and sensorineural hearing loss
0.679 0.321 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.679 0.321 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.679 0.321 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.679 0.321 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.678 0.322 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.678 0.322 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
H91.8 Other specified hearing loss
0.676 0.324 0.000
H91.3 Deaf mutism, not elsewhere classified
0.676 0.324 0.000
H91.2 Sudden idiopathic hearing loss
0.676 0.324 0.000
H91.1 Presbycusis
0.676 0.324 0.000
H91.0 Ototoxic hearing loss
0.676 0.324 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.676 0.324 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.675 0.325 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.675 0.325 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.675 0.325 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.675 0.325 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.675 0.325 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.675 0.325 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.675 0.325 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.675 0.325 0.000
T36 Poisoning by systemic antibiotics
0.675 0.325 0.000
G25 Other extrapyramidal and movement disorders
0.675 0.325 0.000
W00-W19 Falls
0.674 0.326 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.673 0.327 0.000
W29 Contact with other powered hand tools and household machinery
0.673 0.327 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.672 0.328 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.672 0.328 0.000
D37.1 Stomach
0.671 0.329 0.000
C16 Malignant neoplasm of stomach
0.671 0.329 0.000
S60-S69 Injuries to the wrist and hand
0.670 0.330 0.000
Y49.2 Other and unspecified antidepressants
0.670 0.330 0.000
M11 Other crystal arthropathies
0.669 0.330 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.669 0.330 0.000
L85.9 Epidermal thickening, unspecified
0.669 0.331 0.000
L91.8 Other hypertrophic disorders of skin
0.668 0.332 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.668 0.332 0.000
C51 Malignant neoplasm of vulva
0.668 0.332 0.000
C58 Malignant neoplasm of placenta
0.668 0.332 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.668 0.332 0.000
C52 Malignant neoplasm of vagina
0.668 0.332 0.000
N48.9 Disorder of penis, unspecified
0.666 0.333 0.000
N48.5 Ulcer of penis
0.666 0.333 0.000
N48.3 Priapism
0.666 0.333 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.666 0.334 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.666 0.334 0.000
T40.2 Other opioids
0.665 0.334 0.000
N02 Recurrent and persistent haematuria
0.665 0.335 0.000
F99-F99 Unspecified mental disorder
0.663 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.337 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
Q00-Q07 Congenital malformations of the nervous system
0.660 0.340 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
D37.5 Rectum
0.659 0.341 0.000
Chapter X Diseases of the respiratory system
0.658 0.342 0.000
N35.8 Other urethral stricture
0.657 0.343 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.657 0.343 0.000
N35.0 Posttraumatic urethral stricture
0.657 0.343 0.000
M51.8 Other specified intervertebral disk disorders
0.657 0.343 0.000
N30.4 Irradiation cystitis
0.655 0.344 0.000
N30.0 Acute cystitis
0.655 0.344 0.000
G47.3 Sleep apnoea
0.656 0.344 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.655 0.345 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.653 0.347 0.000
Y45.8 Other analgesics and antipyretics
0.653 0.347 0.000
Y45.5 4-Aminophenol derivatives
0.653 0.347 0.000
Y45.4 Antirheumatics
0.653 0.347 0.000
Y45.2 Propionic acid derivatives
0.653 0.347 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.652 0.348 0.000
E27 Other disorders of adrenal gland
0.651 0.348 0.000
G24 Dystonia
0.650 0.349 0.000
G23 Other degenerative diseases of basal ganglia
0.650 0.349 0.000
G21 Secondary Parkinsonism
0.650 0.349 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.650 0.349 0.000
G22 Parkinsonism in diseases classified elsewhere
0.650 0.349 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.650 0.350 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.650 0.350 0.000
Y98 Lifestyle-related condition
0.650 0.350 0.000
Y97 Environmental-pollution-related condition
0.650 0.350 0.000
Y96 Work-related condition
0.650 0.350 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.650 0.350 0.000
C34.1 Upper lobe, bronchus or lung
0.649 0.351 0.000
N75 Diseases of Bartholin's gland
0.649 0.351 0.000
N32.0 Bladder-neck obstruction
0.649 0.351 0.000
C34.3 Lower lobe, bronchus or lung
0.649 0.351 0.000
C22.9 Liver, unspecified
0.649 0.351 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.648 0.352 0.000
C17 Malignant neoplasm of small intestine
0.648 0.352 0.000
C23 Malignant neoplasm of gallbladder
0.648 0.352 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.648 0.352 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.648 0.352 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.648 0.352 0.000
Chapter I Certain infectious and parasitic diseases
0.648 0.352 0.000
M50 Cervical disk disorders
0.647 0.353 0.000
M41.9 Scoliosis, unspecified
0.647 0.353 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.646 0.353 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.645 0.354 0.000
C22.0 Liver cell carcinoma
0.645 0.355 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.643 0.357 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.641 0.358 0.000
C44.8 Overlapping lesion of skin
0.641 0.358 0.000
C78.7 Secondary malignant neoplasm of liver
0.641 0.359 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.641 0.359 0.000
G30-G32 Other degenerative diseases of the nervous system
0.640 0.360 0.000
C80.9 Malignant neoplasm, unspecified
0.640 0.360 0.000
M51.3 Other specified intervertebral disk degeneration
0.640 0.360 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.640 0.360 0.000
M51.9 Intervertebral disk disorder, unspecified
0.640 0.360 0.000
M51.4 Schmorl's nodes
0.640 0.360 0.000
D46 Myelodysplastic syndromes
0.640 0.360 0.000
G47.8 Other sleep disorders
0.639 0.361 0.000
G12 Spinal muscular atrophy and related syndromes
0.638 0.361 0.000
N71.1 Chronic inflammatory disease of uterus
0.638 0.362 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.638 0.362 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.638 0.362 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.638 0.362 0.000
C32 Malignant neoplasm of larynx
0.638 0.362 0.000
C31 Malignant neoplasm of accessory sinuses
0.638 0.362 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.638 0.362 0.000
C37 Malignant neoplasm of thymus
0.638 0.362 0.000
C33 Malignant neoplasm of trachea
0.638 0.362 0.000
L85.8 Other specified epidermal thickening
0.637 0.363 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.637 0.363 0.000
N42.9 Disorder of prostate, unspecified
0.636 0.364 0.000
M06.9 Rheumatoid arthritis, unspecified
0.636 0.364 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.636 0.364 0.000
C66 Malignant neoplasm of ureter
0.636 0.364 0.000
C65 Malignant neoplasm of renal pelvis
0.636 0.364 0.000
C15.5 Lower third of oesophagus
0.635 0.365 0.000
T63 Toxic effect of contact with venomous animals
0.635 0.365 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.635 0.365 0.000
F80-F89 Disorders of psychological development
0.635 0.365 0.000
F70-F79 Mental retardation
0.635 0.365 0.000
N30.1 Interstitial cystitis (chronic)
0.635 0.365 0.000
N48.4 Impotence of organic origin
0.635 0.365 0.000
H81.2 Vestibular neuronitis
0.634 0.366 0.000
Y45.1 Salicylates
0.633 0.367 0.000
T39.0 Salicylates
0.633 0.367 0.000
N03.9 Unspecified
0.632 0.368 0.000
S92 Fracture of foot, except ankle
0.631 0.368 0.000
G81.9 Hemiplegia, unspecified
0.631 0.369 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.630 0.370 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.630 0.370 0.000
T39.4 Antirheumatics, not elsewhere classified
0.630 0.370 0.000
T39.2 Pyrazolone derivatives
0.630 0.370 0.000
M42 Spinal osteochondrosis
0.628 0.372 0.000
M40 Kyphosis and lordosis
0.628 0.372 0.000
M65 Synovitis and tenosynovitis
0.627 0.372 0.000
M54.6 Pain in thoracic spine
0.627 0.373 0.000
S99 Other and unspecified injuries of ankle and foot
0.626 0.374 0.000
S98 Traumatic amputation of ankle and foot
0.626 0.374 0.000
S97 Crushing injury of ankle and foot
0.626 0.374 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.626 0.374 0.000
S95 Injury of blood vessels at ankle and foot level
0.626 0.374 0.000
S94 Injury of nerves at ankle and foot level
0.626 0.374 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.626 0.374 0.000
D00-D09 In situ neoplasms
0.625 0.375 0.000
N32.8 Other specified disorders of bladder
0.624 0.376 0.000
T17 Foreign body in respiratory tract
0.623 0.377 0.000
L40-L45 Papulosquamous disorders
0.623 0.377 0.000
G95 Other diseases of spinal cord
0.623 0.377 0.000
G47.9 Sleep disorder, unspecified
0.622 0.378 0.000
E23 Hypofunction and other disorders of pituitary gland
0.621 0.378 0.000
C67.5 Bladder neck
0.621 0.379 0.000
L10-L14 Bullous disorders
0.619 0.380 0.000
N42.2 Atrophy of prostate
0.619 0.381 0.000
M54.8 Other dorsalgia
0.619 0.381 0.000
M54.0 Panniculitis affecting regions of neck and back
0.619 0.381 0.000
C78.2 Secondary malignant neoplasm of pleura
0.618 0.382 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.617 0.383 0.000
D86.0 Sarcoidosis of lung
0.617 0.383 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.616 0.384 0.000
G83 Other paralytic syndromes
0.615 0.384 0.000
G80 Infantile cerebral palsy
0.615 0.384 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.615 0.385 0.000
G62 Other polyneuropathies
0.614 0.385 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.614 0.386 0.000
D37.7 Other digestive organs
0.614 0.386 0.000
D86.9 Sarcoidosis, unspecified
0.613 0.387 0.000
M24 Other specific joint derangements
0.613 0.387 0.000
Chapter VII Diseases of the eye and adnexa
0.612 0.388 0.000
M54.9 Dorsalgia, unspecified
0.612 0.388 0.000
C44.7 Skin of lower limb, including hip
0.610 0.390 0.000
M54.36 Sciatica (Lumbar region)
0.610 0.390 0.000
F05.9 Delirium, unspecified
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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