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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28366130
log Bayes Factor = 82.5897
Chromosome 6   position 31,363,805  (GRCh37) Explore rs28366130 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
M07.30 Other psoriatic arthropathies (Multiple sites)
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
M07.3 Other psoriatic arthropathies
0.998 0.002 0.000
M45 Ankylosing spondylitis
0.998 0.002 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.000 0.004 0.996
E27 Other disorders of adrenal gland
0.000 0.004 0.996
M07.39 Other psoriatic arthropathies (Site unspecified)
0.995 0.005 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.005 0.995
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.010 0.990
E16 Other disorders of pancreatic internal secretion
0.000 0.012 0.988
E16.2 Hypoglycaemia, unspecified
0.000 0.017 0.983
E10.1 With ketoacidosis
0.000 0.019 0.981
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.041 0.959
E05.9 Thyrotoxicosis, unspecified
0.000 0.044 0.956
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.051 0.949
E10.4 With neurological complications
0.000 0.061 0.939
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.930 0.070 0.000
E10.0 With coma
0.000 0.083 0.917
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.113 0.887
E27.2 Addisonian crisis
0.000 0.132 0.868
E14 Unspecified diabetes mellitus
0.000 0.134 0.866
M07.34 Other psoriatic arthropathies (Hand)
0.862 0.138 0.000
E20 Hypoparathyroidism
0.000 0.142 0.858
K90 Intestinal malabsorption
0.000 0.144 0.856
L40.4 Guttate psoriasis
0.848 0.152 0.000
E10.2 With renal complications
0.000 0.184 0.816
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.810 0.190 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.192 0.808
M07.38 Other psoriatic arthropathies (Other)
0.793 0.207 0.000
L40.1 Generalised pustular psoriasis
0.780 0.220 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.779 0.221 0.000
E14.9 Without complications
0.000 0.225 0.775
M45.X2 Ankylosing spondylitis (Cervical region)
0.765 0.235 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.240 0.760
L40-L45 Papulosquamous disorders
0.759 0.241 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.243 0.757
M07.31 Other psoriatic arthropathies (Shoulder region)
0.748 0.252 0.000
L40.8 Other psoriasis
0.743 0.257 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.742 0.258 0.000
E10.5 With peripheral circulatory complications
0.000 0.263 0.737
E10.6 With other specified complications
0.000 0.267 0.733
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.268 0.732
K90.8 Other intestinal malabsorption
0.000 0.269 0.731
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.284 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.284 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.284 0.716
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.286 0.714
E27.0 Other adrenocortical overactivity
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.287 0.713
E32 Diseases of thymus
0.000 0.287 0.713
E31 Polyglandular dysfunction
0.000 0.287 0.713
E30 Disorders of puberty, not elsewhere classified
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E05.5 Thyroid crisis or storm
0.000 0.290 0.710
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.710
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.710
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.290 0.710
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.291 0.708
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.291 0.708
E16.4 Abnormal secretion of gastrin
0.000 0.291 0.708
E16.3 Increased secretion of glucagon
0.000 0.291 0.708
E03.1 Congenital hypothyroidism without goitre
0.000 0.298 0.702
E27.8 Other specified disorders of adrenal gland
0.000 0.299 0.700
L42 Pityriasis rosea
0.700 0.300 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.302 0.698
L40.3 Pustulosis palmaris et plantaris
0.687 0.313 0.000
E25 Adrenogenital disorders
0.000 0.314 0.686
E40-E46 Malnutrition
0.000 0.325 0.675
E14.6 With other specified complications
0.000 0.332 0.668
E34 Other endocrine disorders
0.000 0.333 0.667
E10.8 With unspecified complications
0.000 0.337 0.663
E07 Other disorders of thyroid
0.000 0.338 0.662
E14.1 With ketoacidosis
0.000 0.352 0.648
E23 Hypofunction and other disorders of pituitary gland
0.000 0.357 0.643
E26 Hyperaldosteronism
0.000 0.363 0.637
E14.5 With peripheral circulatory complications
0.000 0.370 0.630
E22 Hyperfunction of pituitary gland
0.000 0.373 0.627
E14.2 Withrenal complications
0.000 0.375 0.625
E28 Ovarian dysfunction
0.000 0.377 0.623
E14.7 With multiple complications
0.000 0.379 0.621
E14.0 With coma
0.000 0.379 0.621
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.384 0.616
E20.8 Other hypoparathyroidism
0.000 0.385 0.615
E20.1 Pseudohypoparathyroidism
0.000 0.385 0.615
E20.0 Idiopathic hypoparathyroidism
0.000 0.385 0.615
E05.8 Other thyrotoxicosis
0.000 0.386 0.614
K90.3 Pancreatic steatorrhoea
0.000 0.386 0.613
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.386 0.613
K90.1 Tropical sprue
0.000 0.386 0.613
E03.8 Other specified hypothyroidism
0.000 0.392 0.608
L41 Parapsoriasis
0.600 0.400 0.000
E13 Other specified diabetes mellitus
0.000 0.403 0.597
E14.3 With ophthalmic complications
0.000 0.403 0.597
E14.8 With unspecified complications
0.000 0.409 0.590
E06 Thyroiditis
0.000 0.412 0.587
E07.8 Other specified disorders of thyroid
0.000 0.439 0.561
E14.4 With neurological complications
0.000 0.441 0.559
E23.2 Diabetes insipidus
0.000 0.443 0.556
L44 Other papulosquamous disorders
0.544 0.456 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.544 0.456 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.457 0.543
E29 Testicular dysfunction
0.000 0.458 0.542
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.460 0.540
E27.9 Disorder of adrenal gland, unspecified
0.000 0.471 0.528
L43 Lichen planus
0.520 0.480 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E28.3 Primary ovarian failure
0.000 0.489 0.511
E30.9 Disorder of puberty, unspecified
0.000 0.489 0.511
E30.8 Other disorders of puberty
0.000 0.489 0.511
E30.1 Precocious puberty
0.000 0.489 0.511
E30.0 Delayed puberty
0.000 0.489 0.511
E31.9 Polyglandular dysfunction, unspecified
0.000 0.489 0.511
E31.8 Other polyglandular dysfunction
0.000 0.489 0.511
E31.1 Polyglandular hyperfunction
0.000 0.489 0.511
E31.0 Autoimmune polyglandular failure
0.000 0.489 0.511
E32.9 Disease of thymus, unspecified
0.000 0.489 0.511
E32.8 Other diseases of thymus
0.000 0.489 0.511
E32.1 Abscess of thymus
0.000 0.489 0.511
E32.0 Persistent hyperplasia of thymus
0.000 0.489 0.511
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.489 0.511
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.489 0.511
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.489 0.511
E34.8 Other specified endocrine disorders
0.000 0.491 0.509
E25.9 Adrenogenital disorder, unspecified
0.000 0.508 0.492
E25.8 Other adrenogenital disorders
0.000 0.508 0.492
E65-E68 Obesity and other hyperalimentation
0.000 0.510 0.490
E16.1 Other hypoglycaemia
0.001 0.511 0.488
E23.7 Disorder of pituitary gland, unspecified
0.000 0.512 0.488
L41.1 Pityriasis lichenoides chronica
0.485 0.514 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.516 0.484
E45 Retarded development following protein-energy malnutrition
0.000 0.516 0.484
E43 Unspecified severe protein-energy malnutrition
0.000 0.516 0.484
E42 Marasmic kwashiorkor
0.000 0.516 0.484
E41 Nutritional marasmus
0.000 0.516 0.484
E40 Kwashiorkor
0.000 0.516 0.484
E22.1 Hyperprolactinaemia
0.000 0.520 0.480
E34.5 Androgen resistance syndrome
0.000 0.522 0.478
E34.4 Constitutional tall stature
0.000 0.522 0.478
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.522 0.478
E34.1 Other hypersecretion of intestinal hormones
0.000 0.522 0.478
E07.1 Dyshormogenetic goitre
0.000 0.525 0.475
E07.0 Hypersecretion of calcitonin
0.000 0.525 0.475
M07 Psoriatic and enteropathic arthropathies
0.467 0.533 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.535 0.464
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.539 0.461
E23.1 Drug-induced hypopituitarism
0.000 0.539 0.461
E06.3 Autoimmune thyroiditis
0.000 0.540 0.460
E26.8 Other hyperaldosteronism
0.000 0.543 0.457
E26.1 Secondary hyperaldosteronism
0.000 0.543 0.457
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.550 0.450
E22.8 Other hyperfunction of pituitary gland
0.000 0.550 0.450
E28.9 Ovarian dysfunction, unspecified
0.000 0.553 0.447
E28.8 Other ovarian dysfunction
0.000 0.553 0.447
E28.1 Androgen excess
0.000 0.553 0.447
E28.0 Oestrogen excess
0.000 0.553 0.447
E46 Unspecified protein-energy malnutrition
0.000 0.558 0.442
E26.9 Hyperaldosteronism, unspecified
0.000 0.562 0.437
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.436 0.564 0.000
L41.9 Parapsoriasis, unspecified
0.430 0.570 0.000
L41.8 Other parapsoriasis
0.430 0.570 0.000
L41.5 Retiform parapsoriasis
0.430 0.570 0.000
L41.4 Large plaque parapsoriasis
0.430 0.570 0.000
L41.3 Small plaque parapsoriasis
0.430 0.570 0.000
L41.2 Lymphomatoid papulosis
0.430 0.570 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.430 0.570 0.000
E13.8 With unspecified complications
0.000 0.572 0.428
E13.7 With multiple complications
0.000 0.572 0.428
E13.6 With other specified complications
0.000 0.572 0.428
E13.5 With peripheral circulatory complications
0.000 0.572 0.428
E13.4 With neurological complications
0.000 0.572 0.428
E13.3 With ophthalmic complications
0.000 0.572 0.428
E13.2 With renal complications
0.000 0.572 0.428
E13.1 With ketoacidosis
0.000 0.572 0.428
E13.0 With coma
0.000 0.572 0.428
E06.4 Drug-induced thyroiditis
0.000 0.579 0.421
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.579 0.421
E06.0 Acute thyroiditis
0.000 0.579 0.421
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.418 0.582 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.592 0.408
E23.6 Other disorders of pituitary gland
0.000 0.594 0.406
E26.0 Primary hyperaldosteronism
0.000 0.594 0.406
E34.3 Short stature, not elsewhere classified
0.000 0.599 0.400
E06.5 Other chronic thyroiditis
0.000 0.606 0.394
E50-E64 Other nutritional deficiencies
0.000 0.607 0.393
L44.9 Papulosquamous disorder, unspecified
0.390 0.609 0.000
L44.8 Other specified papulosquamous disorders
0.390 0.609 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.390 0.609 0.000
L44.3 Lichen ruber moniliformis
0.390 0.609 0.000
L44.2 Lichen striatus
0.390 0.609 0.000
L44.1 Lichen nitidus
0.390 0.609 0.000
L44.0 Pityriasis rubra pilaris
0.390 0.609 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.611 0.388
E29.8 Other testicular dysfunction
0.000 0.611 0.388
E29.0 Testicular hyperfunction
0.000 0.611 0.388
C82.0 Small cleaved cell, follicular
0.385 0.615 0.000
L43.9 Lichen planus, unspecified
0.383 0.617 0.000
L43.3 Subacute (active) lichen planus
0.373 0.627 0.000
L43.2 Lichenoid drug reaction
0.373 0.627 0.000
L43.1 Bullous lichen planus
0.373 0.627 0.000
L43.0 Hypertrophic lichen planus
0.373 0.627 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.630 0.370
E24 Cushing's syndrome
0.001 0.632 0.367
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.368 0.632 0.000
E34.0 Carcinoid syndrome
0.000 0.636 0.364
E65 Localised adiposity
0.000 0.645 0.355
E06.1 Subacute thyroiditis
0.000 0.646 0.354
E06.9 Thyroiditis, unspecified
0.000 0.648 0.351
E67 Other hyperalimentation
0.000 0.649 0.351
E68 Sequelae of hyperalimentation
0.000 0.649 0.351
E44.1 Mild protein-energy malnutrition
0.000 0.653 0.347
E44.0 Moderate protein-energy malnutrition
0.000 0.653 0.347
C82.1 Mixed small cleaved and large cell, follicular
0.341 0.658 0.000
C82.4 Follicular lymphoma grade IIIb
0.339 0.660 0.000
M07.6 Other enteropathic arthropathies
0.335 0.665 0.000
M07.5 Arthropathy in ulcerative colitis
0.335 0.665 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.335 0.665 0.000
M07.2 Psoriatic spondylitis
0.335 0.665 0.000
M07.1 Arthritis mutilans
0.335 0.665 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.335 0.665 0.000
L43.8 Other lichen planus
0.334 0.665 0.000
C82.3 Follicular lymphoma grade IIIa
0.327 0.673 0.000
C82.2 Large cell, follicular
0.321 0.678 0.000
E13.9 Without complications
0.000 0.691 0.308
C82.6 Cutaneous follicle centre lymphoma
0.300 0.700 0.000
C82.5 Diffuse follicle centre lymphoma
0.300 0.700 0.000
E53 Deficiency of other B group vitamins
0.000 0.707 0.293
E51 Thiamine deficiency
0.000 0.707 0.292
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.718 0.282
E63 Other nutritional deficiencies
0.000 0.718 0.282
E50 Vitamin A deficiency
0.000 0.718 0.282
E60 Dietary zinc deficiency
0.000 0.718 0.282
E59 Dietary selenium deficiency
0.000 0.718 0.282
E54 Ascorbic acid deficiency
0.000 0.718 0.282
E52 Niacin deficiency [pellagra]
0.000 0.718 0.282
E56 Other vitamin deficiencies
0.000 0.722 0.278
E24.8 Other Cushing's syndrome
0.001 0.736 0.263
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.736 0.263
E24.3 Ectopic ACTH syndrome
0.001 0.736 0.263
E24.1 Nelson's syndrome
0.001 0.736 0.263
E67.8 Other specified hyperalimentation
0.000 0.748 0.252
E67.3 Hypervitaminosis D
0.000 0.748 0.252
E67.2 Megavitamin-B6 syndrome
0.000 0.748 0.252
E67.1 Hypercarotenaemia
0.000 0.748 0.252
E67.0 Hypervitaminosis A
0.000 0.748 0.252
E24.2 Drug-induced Cushing's syndrome
0.001 0.754 0.244
E58 Dietary calcium deficiency
0.000 0.757 0.242
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.240 0.760 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.240 0.760 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.240 0.760 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.240 0.760 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.240 0.760 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.240 0.760 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.240 0.760 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.240 0.760 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.240 0.760 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.240 0.760 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.240 0.760 0.000
M07.18 Arthritis mutilans (Other)
0.240 0.760 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.240 0.760 0.000
M07.16 Arthritis mutilans (Lower leg)
0.240 0.760 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.240 0.760 0.000
M07.14 Arthritis mutilans (Hand)
0.240 0.760 0.000
M07.13 Arthritis mutilans (Forearm)
0.240 0.760 0.000
M07.12 Arthritis mutilans (Upper arm)
0.240 0.760 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.240 0.760 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.240 0.760 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.240 0.760 0.000
M07.28 Psoriatic spondylitis (Other)
0.240 0.760 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.240 0.760 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.240 0.760 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.240 0.760 0.000
M07.24 Psoriatic spondylitis (Hand)
0.240 0.760 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.240 0.760 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.240 0.760 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.240 0.760 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.240 0.760 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.240 0.760 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.240 0.760 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.240 0.760 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.240 0.760 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.240 0.760 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.240 0.760 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.240 0.760 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.240 0.760 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.240 0.760 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.240 0.760 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.240 0.760 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.240 0.760 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.240 0.760 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.240 0.760 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.240 0.760 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.240 0.760 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.240 0.760 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.240 0.760 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.240 0.760 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.240 0.760 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.240 0.760 0.000
M07.68 Other enteropathic arthropathies (Other)
0.240 0.760 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.240 0.760 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.240 0.760 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.240 0.760 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.240 0.760 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.240 0.760 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.240 0.760 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.240 0.760 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.240 0.760 0.000
E04 Other non-toxic goitre
0.000 0.768 0.232
E51.2 Wernicke's encephalopathy
0.000 0.779 0.220
E29.1 Testicular hypofunction
0.000 0.782 0.217
E53.9 Vitamin B deficiency, unspecified
0.000 0.783 0.217
E07.9 Disorder of thyroid, unspecified
0.000 0.785 0.215
E53.8 Deficiency of other specified B group vitamins
0.000 0.785 0.215
E24.0 Pituitary-dependent Cushing's disease
0.001 0.789 0.209
E53.1 Pyridoxine deficiency
0.000 0.790 0.210
E53.0 Riboflavin deficiency
0.000 0.790 0.210
E51.9 Thiamine deficiency, unspecified
0.000 0.790 0.210
E51.8 Other manifestations of thiamine deficiency
0.000 0.790 0.210
E51.1 Beriberi
0.000 0.790 0.210
E55 Vitamin D deficiency
0.000 0.790 0.210
E28.2 Polycystic ovarian syndrome
0.000 0.796 0.204
E50.9 Vitamin A deficiency, unspecified
0.000 0.797 0.202
E50.8 Other manifestations of vitamin A deficiency
0.000 0.797 0.202
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.797 0.202
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.797 0.202
E50.5 Vitamin A deficiency with night blindness
0.000 0.797 0.202
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.797 0.202
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.797 0.202
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.797 0.202
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.797 0.202
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.797 0.202
E63.9 Nutritional deficiency, unspecified
0.000 0.797 0.202
E63.8 Other specified nutritional deficiencies
0.000 0.797 0.202
E63.1 Imbalance of constituents of food intake
0.000 0.797 0.202
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.797 0.202
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.797 0.202
E64.8 Sequelae of other nutritional deficiencies
0.000 0.797 0.202
E64.3 Sequelae of rickets
0.000 0.797 0.202
E64.2 Sequelae of vitamin C deficiency
0.000 0.797 0.202
E64.1 Sequelae of vitamin A deficiency
0.000 0.797 0.202
E64.0 Sequelae of protein-energy malnutrition
0.000 0.797 0.202
E56.9 Vitamin deficiency, unspecified
0.000 0.800 0.199
E56.8 Deficiency of other vitamins
0.000 0.800 0.199
E56.0 Deficiency of vitamin E
0.000 0.800 0.199
E11 Non-insulin-dependent diabetes mellitus
0.000 0.801 0.199
E56.1 Deficiency of vitamin K
0.000 0.804 0.196
E04.0 Non-toxic diffuse goitre
0.000 0.810 0.190
E04.8 Other specified non-toxic goitre
0.000 0.833 0.167
E11.5 With peripheral circulatory complications
0.000 0.833 0.167
E23.0 Hypopituitarism
0.000 0.836 0.163
E61 Deficiency of other nutrient elements
0.001 0.836 0.163
E11.3 With ophthalmic complications
0.000 0.843 0.157
E55.0 Rickets, active
0.000 0.849 0.150
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.853 0.147
E11.7 With multiple complications
0.000 0.857 0.143
E11.8 With unspecified complications
0.000 0.860 0.139
E04.1 Non-toxic single thyroid nodule
0.000 0.863 0.137
D69.6 Thrombocytopenia, unspecified
0.000 0.866 0.134
E11.6 With other specified complications
0.000 0.867 0.133
M45-M49 Spondylopathies
0.133 0.867 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.869 0.131
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.870 0.130
E11.1 With ketoacidosis
0.000 0.873 0.126
E11.0 With coma
0.000 0.875 0.125
E24.9 Cushing's syndrome, unspecified
0.002 0.882 0.115
E61.9 Deficiency of nutrient element, unspecified
0.001 0.883 0.117
E61.8 Deficiency of other specified nutrient elements
0.001 0.883 0.117
E61.7 Deficiency of multiple nutrient elements
0.001 0.883 0.117
E61.6 Vanadium deficiency
0.001 0.883 0.117
E61.5 Molybdenum deficiency
0.001 0.883 0.117
E61.4 Chromium deficiency
0.001 0.883 0.117
E61.3 Manganese deficiency
0.001 0.883 0.117
E61.0 Copper deficiency
0.001 0.883 0.117
D69.5 Secondary thrombocytopenia
0.000 0.884 0.116
E66 Obesity
0.000 0.887 0.113
E11.2 With renal complications
0.000 0.889 0.111
D69.0 Allergic purpura
0.000 0.893 0.107
E61.2 Magnesium deficiency
0.001 0.898 0.102
D69.4 Other primary thrombocytopenia
0.000 0.898 0.102
D69.2 Other nonthrombocytopenic purpura
0.000 0.900 0.100
E21.4 Other specified disorders of parathyroid gland
0.000 0.904 0.095
D69.8 Other specified haemorrhagic conditions
0.000 0.905 0.094
D69.1 Qualitative platelet defects
0.000 0.910 0.090
G35 Multiple sclerosis
0.000 0.911 0.089
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.911 0.088
E21.2 Other hyperparathyroidism
0.000 0.912 0.087
M05-M14 Inflammatory polyarthropathies
0.085 0.915 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.915 0.085
M49 Spondylopathies in diseases classified elsewhere
0.084 0.916 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.918 0.082
E66.0 Obesity due to excess calories
0.000 0.918 0.082
E66.1 Drug-induced obesity
0.000 0.919 0.081
E11.4 With neurological complications
0.000 0.919 0.081
D69.9 Haemorrhagic condition, unspecified
0.000 0.920 0.080
E55.9 Vitamin D deficiency, unspecified
0.000 0.922 0.078
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.924 0.076
M11 Other crystal arthropathies
0.069 0.930 0.000
M48 Other spondylopathies
0.069 0.931 0.000
M46 Other inflammatory spondylopathies
0.067 0.933 0.000
K90-K93 Other diseases of the digestive system
0.000 0.933 0.067
M08 Juvenile arthritis
0.066 0.934 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.062 0.938 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.061 0.939 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.060 0.940 0.000
M49.4 Neuropathic spondylopathy
0.060 0.940 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.060 0.940 0.000
M49.2 Enterobacterial spondylitis
0.060 0.940 0.000
M49.1 Brucella spondylitis
0.060 0.940 0.000
M49.0 Tuberculosis of spine
0.060 0.940 0.000
M00-M03 Infectious arthropathies
0.058 0.942 0.000
M48.9 Spondylopathy, unspecified
0.057 0.942 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.943 0.057
M35.3 Polymyalgia rheumatica
0.000 0.944 0.056
M11.2 Other chondrocalcinosis
0.056 0.944 0.000
M11.9 Crystal arthropathy, unspecified
0.055 0.945 0.000
M35 Other systemic involvement of connective tissue
0.000 0.945 0.055
M12 Other specific arthropathies
0.054 0.946 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.054 0.946 0.000
M46.4 Discitis, unspecified
0.053 0.947 0.000
M08.0 Juvenile rheumatoid arthritis
0.053 0.947 0.000
M00 Pyogenic arthritis
0.052 0.948 0.000
M48.8 Other specified spondylopathies
0.052 0.948 0.000
M13 Other arthritis
0.052 0.948 0.000
M14 Arthropathies in other diseases classified elsewhere
0.051 0.949 0.000
M02 Reactive arthropathies
0.051 0.949 0.000
M51.8 Other specified intervertebral disk disorders
0.050 0.950 0.000
M11.1 Familial chondrocalcinosis
0.050 0.950 0.000
M11.0 Hydroxyapatite deposition disease
0.050 0.950 0.000
M48.4 Fatigue fracture of vertebra
0.050 0.950 0.000
M48.3 Traumatic spondylopathy
0.050 0.950 0.000
M48.2 Kissing spine
0.050 0.950 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.050 0.950 0.000
M50-M54 Other dorsopathies
0.049 0.951 0.000
M47 Spondylosis
0.049 0.951 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.049 0.951 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.049 0.951 0.000
M46.8 Other specified inflammatory spondylopathies
0.048 0.951 0.000
M46.5 Other infective spondylopathies
0.048 0.951 0.000
M46.2 Osteomyelitis of vertebra
0.048 0.951 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.048 0.952 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.952 0.048
M51 Other intervertebral disk disorders
0.048 0.952 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.048 0.952 0.000
M08.9 Juvenile arthritis, unspecified
0.048 0.952 0.000
M08.8 Other juvenile arthritis
0.048 0.952 0.000
M08.4 Pauciarticular juvenile arthritis
0.048 0.952 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.048 0.952 0.000
M08.2 Juvenile arthritis with systemic onset
0.048 0.952 0.000
M08.1 Juvenile ankylosing spondylitis
0.048 0.952 0.000
M00.9 Pyogenic arthritis, unspecified
0.048 0.952 0.000
M11.8 Other specified crystal arthropathies
0.047 0.953 0.000
M05 Seropositive rheumatoid arthritis
0.047 0.953 0.000
M35.1 Other overlap syndromes
0.000 0.953 0.047
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.954 0.046
K59.8 Other specified functional intestinal disorders
0.046 0.954 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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