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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28366155
log Bayes Factor = 20.5581
Chromosome 6   position 31,658,634  (GRCh37) Explore rs28366155 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
K90.0 Coeliac disease
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
M06 Other rheumatoid arthritis
0.000 0.004 0.996
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.012 0.988
M05-M14 Inflammatory polyarthropathies
0.000 0.013 0.987
L20-L30 Dermatitis and eczema
0.000 0.029 0.971
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.038 0.962
M07 Psoriatic and enteropathic arthropathies
0.000 0.044 0.956
L29 Pruritus
0.000 0.045 0.955
M06.0 Seronegative rheumatoid arthritis
0.000 0.061 0.939
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.062 0.938
E10.1 With ketoacidosis
0.000 0.062 0.938
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.063 0.937
M07.3 Other psoriatic arthropathies
0.000 0.066 0.934
# Top node
0.000 0.070 0.930
L29.0 Pruritus ani
0.000 0.070 0.930
D50-D53 Nutritional anaemias
0.000 0.074 0.926
D50 Iron deficiency anaemia
0.000 0.084 0.916
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.090 0.910
L57.0 Actinic keratosis
0.000 0.092 0.908
D60-D64 Aplastic and other anaemias
0.000 0.095 0.905
E50-E64 Other nutritional deficiencies
0.000 0.100 0.900
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.102 0.898
D50.9 Iron deficiency anaemia, unspecified
0.000 0.103 0.897
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.111 0.889
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.119 0.881
E06 Thyroiditis
0.000 0.120 0.880
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.121 0.879
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.124 0.876
E10.5 With peripheral circulatory complications
0.000 0.127 0.873
M05 Seropositive rheumatoid arthritis
0.000 0.129 0.871
E10.4 With neurological complications
0.000 0.134 0.866
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.137 0.863
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.137 0.863
L08 Other local infections of skin and subcutaneous tissue
0.000 0.138 0.862
D64 Other anaemias
0.000 0.141 0.859
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.155 0.845
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.159 0.841
L40.0 Psoriasis vulgaris
0.000 0.161 0.839
D61 Other aplastic anaemias
0.000 0.166 0.834
L29.9 Pruritus, unspecified
0.000 0.170 0.830
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.172 0.828
D64.9 Anaemia, unspecified
0.000 0.173 0.827
E53 Deficiency of other B group vitamins
0.000 0.187 0.813
Chapter X Diseases of the respiratory system
0.000 0.191 0.809
D80-D89 Certain disorders involving the immune mechanism
0.000 0.192 0.808
D68 Other coagulation defects
0.000 0.199 0.801
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.200 0.800
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.202 0.798
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.212 0.788
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.212 0.788
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.216 0.784
D61.9 Aplastic anaemia, unspecified
0.000 0.217 0.783
E06.3 Autoimmune thyroiditis
0.000 0.217 0.783
E05.9 Thyrotoxicosis, unspecified
0.000 0.228 0.772
L27 Dermatitis due to substances taken internally
0.000 0.232 0.768
D52 Folate deficiency anaemia
0.000 0.239 0.761
L43 Lichen planus
0.000 0.240 0.760
M14 Arthropathies in other diseases classified elsewhere
0.000 0.241 0.759
E65-E68 Obesity and other hyperalimentation
0.000 0.247 0.753
E53.8 Deficiency of other specified B group vitamins
0.000 0.248 0.752
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.253 0.747
E20-E35 Disorders of other endocrine glands
0.000 0.267 0.733
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.268 0.732
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.268 0.732
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.269 0.731
D86 Sarcoidosis
0.000 0.272 0.728
E55 Vitamin D deficiency
0.000 0.272 0.728
L28 Lichen simplex chronicus and prurigo
0.000 0.276 0.724
J09-J18 Influenza and pneumonia
0.000 0.278 0.722
D50.8 Other iron deficiency anaemias
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
J40-J47 Chronic lower respiratory diseases
0.000 0.283 0.717
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
M06.8 Other specified rheumatoid arthritis
0.000 0.286 0.714
M06.2 Rheumatoid bursitis
0.000 0.286 0.714
M06.1 Adult-onset Still's disease
0.000 0.286 0.714
L20 Atopic dermatitis
0.000 0.288 0.712
M12 Other specific arthropathies
0.000 0.292 0.708
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.292 0.708
M08 Juvenile arthritis
0.000 0.292 0.708
M20-M25 Other joint disorders
0.000 0.292 0.708
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.296 0.704
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.296 0.704
M35 Other systemic involvement of connective tissue
0.000 0.297 0.703
Chapter I Certain infectious and parasitic diseases
0.000 0.298 0.702
M35.3 Polymyalgia rheumatica
0.000 0.300 0.700
E27 Other disorders of adrenal gland
0.000 0.300 0.700
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.301 0.699
L25 Unspecified contact dermatitis
0.000 0.304 0.696
L24 Irritant contact dermatitis
0.000 0.304 0.696
L23 Allergic contact dermatitis
0.000 0.304 0.696
L21 Seborrhoeic dermatitis
0.000 0.304 0.696
L26 Exfoliative dermatitis
0.000 0.304 0.696
L22 Diaper [napkin] dermatitis
0.000 0.304 0.696
D68.9 Coagulation defect, unspecified
0.000 0.307 0.693
L10-L14 Bullous disorders
0.000 0.308 0.692
M11 Other crystal arthropathies
0.000 0.309 0.691
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.310 0.690
L58 Radiodermatitis
0.000 0.310 0.690
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.310 0.690
L55 Sunburn
0.000 0.310 0.690
M06.3 Rheumatoid nodule
0.000 0.312 0.688
M07.6 Other enteropathic arthropathies
0.000 0.314 0.686
M07.5 Arthropathy in ulcerative colitis
0.000 0.314 0.686
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.314 0.686
M07.2 Psoriatic spondylitis
0.000 0.314 0.686
M07.1 Arthritis mutilans
0.000 0.314 0.686
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.314 0.686
J18 Pneumonia, organism unspecified
0.000 0.315 0.685
E14 Unspecified diabetes mellitus
0.000 0.315 0.685
L29.8 Other pruritus
0.000 0.315 0.685
L29.3 Anogenital pruritus, unspecified
0.000 0.315 0.685
L29.1 Pruritus scroti
0.000 0.315 0.685
L29.2 Pruritus vulvae
0.000 0.316 0.684
J20-J22 Other acute lower respiratory infections
0.000 0.316 0.684
J47 Bronchiectasis
0.000 0.318 0.682
E40-E46 Malnutrition
0.000 0.322 0.678
D55-D59 Haemolytic anaemias
0.000 0.323 0.677
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.325 0.675
M10 Gout
0.000 0.326 0.674
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.327 0.673
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.327 0.673
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.327 0.673
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.327 0.673
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.327 0.673
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.327 0.673
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.327 0.673
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.327 0.673
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.327 0.672
L57.5 Actinic granuloma
0.000 0.327 0.672
L57.4 Cutis laxa senilis
0.000 0.327 0.672
L57.3 Poikiloderma of Civatte
0.000 0.327 0.672
L57.2 Cutis rhomboidalis nuchae
0.000 0.327 0.672
L57.1 Actinic reticuloid
0.000 0.327 0.672
M07.38 Other psoriatic arthropathies (Other)
0.000 0.330 0.670
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.330 0.670
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.330 0.670
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.330 0.670
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.330 0.670
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.330 0.670
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.330 0.670
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.330 0.670
D68.5 Primary Thrombophilia
0.000 0.330 0.669
L42 Pityriasis rosea
0.000 0.331 0.669
J81 Pulmonary oedema
0.000 0.332 0.668
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.333 0.667
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.337 0.663
Chapter XXII Codes for special purposes
0.000 0.338 0.662
E06.9 Thyroiditis, unspecified
0.000 0.339 0.661
E10.8 With unspecified complications
0.000 0.340 0.660
D69 Purpura and other haemorrhagic conditions
0.000 0.343 0.657
D50.1 Sideropenic dysphagia
0.000 0.343 0.657
E13 Other specified diabetes mellitus
0.000 0.346 0.653
E05.5 Thyroid crisis or storm
0.000 0.347 0.652
E05.4 Thyrotoxicosis factitia
0.000 0.347 0.652
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.347 0.652
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.347 0.652
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.350 0.650
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.351 0.649
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.355 0.645
E63 Other nutritional deficiencies
0.000 0.355 0.645
E56 Other vitamin deficiencies
0.000 0.355 0.645
E51 Thiamine deficiency
0.000 0.355 0.645
E50 Vitamin A deficiency
0.000 0.355 0.645
E60 Dietary zinc deficiency
0.000 0.355 0.645
E59 Dietary selenium deficiency
0.000 0.355 0.645
E58 Dietary calcium deficiency
0.000 0.355 0.645
E54 Ascorbic acid deficiency
0.000 0.355 0.645
E52 Niacin deficiency [pellagra]
0.000 0.355 0.645
J18.1 Lobar pneumonia, unspecified
0.000 0.356 0.644
D52.9 Folate deficiency anaemia, unspecified
0.000 0.358 0.642
D53 Other nutritional anaemias
0.000 0.362 0.637
L04 Acute lymphadenitis
0.000 0.363 0.637
L01 Impetigo
0.000 0.363 0.637
L00 Staphylococcal scalded skin syndrome
0.000 0.363 0.637
D86.9 Sarcoidosis, unspecified
0.000 0.363 0.637
B35-B49 Mycoses
0.000 0.363 0.637
D51 Vitamin B12 deficiency anaemia
0.000 0.363 0.637
E27.1 Primary adrenocortical insufficiency
0.000 0.364 0.636
M80-M85 Disorders of bone density and structure
0.000 0.367 0.633
E06.5 Other chronic thyroiditis
0.000 0.369 0.631
E06.4 Drug-induced thyroiditis
0.000 0.369 0.631
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.369 0.631
E06.1 Subacute thyroiditis
0.000 0.369 0.631
E06.0 Acute thyroiditis
0.000 0.369 0.631
E04 Other non-toxic goitre
0.000 0.372 0.628
M05.8 Other seropositive rheumatoid arthritis
0.000 0.375 0.625
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.375 0.625
M05.2 Rheumatoid vasculitis
0.000 0.375 0.625
M05.1 Rheumatoid lung disease
0.000 0.375 0.625
M05.0 Felty's syndrome
0.000 0.375 0.625
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.376 0.624
J80 Adult respiratory distress syndrome
0.000 0.378 0.622
J18.9 Pneumonia, unspecified
0.000 0.378 0.622
J44 Other chronic obstructive pulmonary disease
0.000 0.378 0.622
D68.8 Other specified coagulation defects
0.000 0.380 0.620
D67 Hereditary factor IX deficiency
0.000 0.381 0.619
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.381 0.619
L08.1 Erythrasma
0.000 0.382 0.618
L08.0 Pyoderma
0.000 0.382 0.618
D66 Hereditary factor VIII deficiency
0.000 0.383 0.616
D64.8 Other specified anaemias
0.000 0.384 0.616
D64.4 Congenital dyserythropoietic anaemia
0.000 0.384 0.616
D64.3 Other sideroblastic anaemias
0.000 0.384 0.616
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.384 0.616
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.384 0.616
D64.0 Hereditary sideroblastic anaemia
0.000 0.384 0.616
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.384 0.616
J30-J39 Other diseases of upper respiratory tract
0.000 0.388 0.612
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.390 0.610
B25-B34 Other viral diseases
0.000 0.393 0.607
M00-M03 Infectious arthropathies
0.000 0.393 0.607
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.393 0.606
D86.0 Sarcoidosis of lung
0.000 0.394 0.606
E55.9 Vitamin D deficiency, unspecified
0.000 0.395 0.605
B37 Candidiasis
0.000 0.395 0.605
M80 Osteoporosis with pathological fracture
0.000 0.396 0.604
E66 Obesity
0.000 0.397 0.603
J22 Unspecified acute lower respiratory infection
0.000 0.397 0.603
M06.4 Inflammatory polyarthropathy
0.000 0.399 0.601
D61.8 Other specified aplastic anaemias
0.000 0.402 0.598
D61.3 Idiopathic aplastic anaemia
0.000 0.402 0.598
D61.2 Aplastic anaemia due to other external agents
0.000 0.402 0.598
D61.1 Drug-induced aplastic anaemia
0.000 0.402 0.598
D61.0 Constitutional aplastic anaemia
0.000 0.402 0.598
M14.6 Neuropathic arthropathy
0.000 0.404 0.595
B37.8 Candidiasis of other sites
0.000 0.405 0.595
J32 Chronic sinusitis
0.000 0.409 0.591
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.409 0.591
L43.9 Lichen planus, unspecified
0.000 0.410 0.590
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.411 0.589
M34 Systemic sclerosis
0.000 0.413 0.587
E61 Deficiency of other nutrient elements
0.000 0.415 0.585
M91-M94 Chondropathies
0.000 0.416 0.584
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.416 0.584
E53.9 Vitamin B deficiency, unspecified
0.000 0.417 0.583
E53.1 Pyridoxine deficiency
0.000 0.417 0.583
E53.0 Riboflavin deficiency
0.000 0.417 0.583
J10 Influenza due to identified influenza virus
0.000 0.417 0.583
M60-M63 Disorders of muscles
0.000 0.418 0.581
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.418 0.581
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.419 0.581
D68.6 Other Thrombophilia
0.000 0.420 0.580
D84 Other immunodeficiencies
0.000 0.420 0.579
D83 Common variable immunodeficiency
0.000 0.420 0.579
D82 Immunodeficiency associated with other major defects
0.000 0.420 0.579
D81 Combined immunodeficiencies
0.000 0.420 0.579
M31 Other necrotising vasculopathies
0.000 0.425 0.575
D68.0 Von Willebrand's disease
0.000 0.425 0.575
D68.4 Acquired coagulation factor deficiency
0.000 0.426 0.574
D68.1 Hereditary factor XI deficiency
0.000 0.426 0.574
L83 Acanthosis nigricans
0.000 0.426 0.574
E66.8 Other obesity
0.000 0.427 0.573
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.428 0.572
L82 Seborrhoeic keratosis
0.000 0.429 0.571
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.430 0.570
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.434 0.566
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.434 0.566
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.435 0.565
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.435 0.565
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.435 0.565
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.435 0.565
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.435 0.565
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.435 0.565
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.435 0.565
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.435 0.565
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.435 0.565
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.436 0.564
J32.9 Chronic sinusitis, unspecified
0.000 0.437 0.563
E05.8 Other thyrotoxicosis
0.000 0.440 0.560
J14 Pneumonia due to Haemophilus influenzae
0.000 0.443 0.557
D80 Immunodeficiency with predominantly antibody defects
0.000 0.445 0.555
J40 Bronchitis, not specified as acute or chronic
0.000 0.445 0.555
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.446 0.554
E11 Non-insulin-dependent diabetes mellitus
0.000 0.447 0.553
M35.7 Hypermobility syndrome
0.000 0.447 0.553
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.449 0.551
L27.8 Dermatitis due to other substances taken internally
0.000 0.449 0.551
L27.2 Dermatitis due to ingested food
0.000 0.449 0.551
L28.0 Lichen simplex chronicus
0.000 0.452 0.547
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.454 0.546
M45-M49 Spondylopathies
0.000 0.454 0.546
D52.8 Other folate deficiency anaemias
0.000 0.455 0.545
D52.1 Drug-induced folate deficiency anaemia
0.000 0.455 0.545
D52.0 Dietary folate deficiency anaemia
0.000 0.455 0.545
L43.8 Other lichen planus
0.000 0.455 0.545
L43.3 Subacute (active) lichen planus
0.000 0.455 0.545
L43.2 Lichenoid drug reaction
0.000 0.455 0.545
L43.1 Bullous lichen planus
0.000 0.455 0.545
L43.0 Hypertrophic lichen planus
0.000 0.455 0.545
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.456 0.544
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.456 0.544
M14.4 Arthropathy in amyloidosis
0.000 0.456 0.544
M14.3 Lipoid dermatoarthritis
0.000 0.456 0.544
M14.2 Diabetic arthropathy
0.000 0.456 0.544
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.456 0.544
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.456 0.544
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.457 0.543
E26 Hyperaldosteronism
0.000 0.458 0.542
E27.9 Disorder of adrenal gland, unspecified
0.000 0.459 0.541
E67 Other hyperalimentation
0.000 0.460 0.540
E68 Sequelae of hyperalimentation
0.000 0.460 0.540
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.462 0.538
M13 Other arthritis
0.000 0.466 0.533
J35 Chronic diseases of tonsils and adenoids
0.000 0.468 0.532
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.470 0.530
L05 Pilonidal cyst
0.000 0.472 0.528
J11 Influenza, virus not identified
0.000 0.472 0.528
D62 Acute posthaemorrhagic anaemia
0.000 0.473 0.527
E07 Other disorders of thyroid
0.001 0.474 0.526
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.474 0.526
E32 Diseases of thymus
0.000 0.474 0.526
E31 Polyglandular dysfunction
0.000 0.474 0.526
E30 Disorders of puberty, not elsewhere classified
0.000 0.474 0.526
E25 Adrenogenital disorders
0.000 0.474 0.526
E20 Hypoparathyroidism
0.000 0.474 0.526
L20.9 Atopic dermatitis, unspecified
0.000 0.474 0.525
J46 Status asthmaticus
0.000 0.475 0.525
D86.3 Sarcoidosis of skin
0.000 0.478 0.522
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.478 0.522
D86.1 Sarcoidosis of lymph nodes
0.000 0.478 0.522
E55.0 Rickets, active
0.000 0.478 0.522
E28 Ovarian dysfunction
0.000 0.479 0.521
L89 Decubitus ulcer
0.000 0.479 0.521
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.480 0.520
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.480 0.520
L28.2 Other prurigo
0.000 0.480 0.519
L28.1 Prurigo nodularis
0.000 0.480 0.519
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.481 0.519
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.481 0.519
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.482 0.518
J09 Influenza due to certain identified influenza virus
0.000 0.482 0.518
M40-M43 Deforming dorsopathies
0.000 0.484 0.516
A00-A09 Intestinal infectious diseases
0.000 0.485 0.515
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
J41 Simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
D59 Acquired haemolytic anaemia
0.000 0.486 0.514
L50-L54 Urticaria and erythema
0.000 0.487 0.513
L41.9 Parapsoriasis, unspecified
0.000 0.487 0.513
L41.8 Other parapsoriasis
0.000 0.487 0.513
L41.5 Retiform parapsoriasis
0.000 0.487 0.513
L41.4 Large plaque parapsoriasis
0.000 0.487 0.513
L41.3 Small plaque parapsoriasis
0.000 0.487 0.513
L41.2 Lymphomatoid papulosis
0.000 0.487 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.487 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.487 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.487 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.487 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.487 0.513
L44.3 Lichen ruber moniliformis
0.000 0.487 0.513
L44.2 Lichen striatus
0.000 0.487 0.513
L44.1 Lichen nitidus
0.000 0.487 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.487 0.513
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.488 0.512
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.488 0.512
M06.18 Adult-onset Still's disease (Other)
0.000 0.488 0.512
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.488 0.512
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.488 0.512
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.488 0.512
M06.14 Adult-onset Still's disease (Hand)
0.000 0.488 0.512
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.488 0.512
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.488 0.512
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.488 0.512
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.488 0.512
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.488 0.512
M06.28 Rheumatoid bursitis (Other)
0.000 0.488 0.512
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.488 0.512
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.488 0.512
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.488 0.512
M06.24 Rheumatoid bursitis (Hand)
0.000 0.488 0.512
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.488 0.512
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.488 0.512
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.488 0.512
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.488 0.512
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.488 0.512
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.488 0.512
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.488 0.512
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.488 0.512
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.488 0.512
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.488 0.512
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.488 0.512
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.488 0.512
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.488 0.512
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.488 0.512
D86.8 Sarcoidosis of other and combined sites
0.000 0.488 0.512
J32.8 Other chronic sinusitis
0.000 0.489 0.511
L20.8 Other atopic dermatitis
0.000 0.490 0.510
L20.0 Besnier's prurigo
0.000 0.490 0.510
A63.0 Anogenital (venereal) warts
0.000 0.490 0.510
M08.9 Juvenile arthritis, unspecified
0.000 0.492 0.507
M08.8 Other juvenile arthritis
0.000 0.492 0.507
M08.4 Pauciarticular juvenile arthritis
0.000 0.492 0.507
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.492 0.507
M08.2 Juvenile arthritis with systemic onset
0.000 0.492 0.507
M08.1 Juvenile ankylosing spondylitis
0.000 0.492 0.507
M08.0 Juvenile rheumatoid arthritis
0.000 0.492 0.507
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.492 0.507
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.492 0.507
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.492 0.507
M09.0 Juvenile arthritis in psoriasis
0.000 0.492 0.507
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.492 0.507
M12.5 Traumatic arthropathy
0.000 0.492 0.507
M12.4 Intermittent hydrarthrosis
0.000 0.492 0.507
M12.3 Palindromic rheumatism
0.000 0.492 0.507
M12.2 Villonodular synovitis (pigmented)
0.000 0.492 0.507
M12.1 Kaschin-Beck disease
0.000 0.492 0.507
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.492 0.507
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.492 0.507
M32 Systemic lupus erythematosus
0.000 0.492 0.507
E14.3 With ophthalmic complications
0.000 0.493 0.507
B25 Cytomegaloviral disease
0.000 0.493 0.507
J35.0 Chronic tonsillitis
0.000 0.495 0.505
M45 Ankylosing spondylitis
0.000 0.495 0.505
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.496 0.504
M35.8 Other specified systemic involvement of connective tissue
0.000 0.496 0.504
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.496 0.504
M35.5 Multifocal fibrosclerosis
0.000 0.496 0.504
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.496 0.504
M35.2 Behcet's disease
0.000 0.496 0.504
M35.1 Other overlap syndromes
0.000 0.496 0.504
L93 Lupus erythematosus
0.000 0.496 0.503
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.497 0.503
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.497 0.503
A75-A79 Rickettsioses
0.000 0.497 0.503
A70-A74 Other diseases caused by chlamydiae
0.000 0.497 0.503
A65-A69 Other spirochaetal diseases
0.000 0.497 0.503
A20-A28 Certain zoonotic bacterial diseases
0.000 0.497 0.503
A15-A19 Tuberculosis
0.000 0.497 0.503
E27.8 Other specified disorders of adrenal gland
0.000 0.498 0.502
E27.5 Adrenomedullary hyperfunction
0.000 0.498 0.502
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.498 0.502
E27.2 Addisonian crisis
0.000 0.498 0.502
E27.0 Other adrenocortical overactivity
0.000 0.498 0.502
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.498 0.501
L87 Transepidermal elimination disorders
0.000 0.498 0.501
L88 Pyoderma gangrenosum
0.000 0.498 0.501
L86 Keratoderma in diseases classified elsewhere
0.000 0.498 0.501
L80 Vitiligo
0.000 0.498 0.501
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.499 0.501
E65 Localised adiposity
0.000 0.499 0.500
M34.9 Systemic sclerosis, unspecified
0.000 0.500 0.500
M22 Disorders of patella
0.000 0.500 0.500
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.501 0.499
L21.8 Other seborrhoeic dermatitis
0.000 0.501 0.499
L21.1 Seborrhoeic infantile dermatitis
0.000 0.501 0.499
L21.0 Seborrhoea capitis
0.000 0.501 0.499

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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