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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28366175
log Bayes Factor = 37.4163
Chromosome 6   position 32,269,578  (GRCh37) Explore rs28366175 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.002 0.998
H36.0 Diabetic retinopathy
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
D50-D53 Nutritional anaemias
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
D50 Iron deficiency anaemia
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
J20-J22 Other acute lower respiratory infections
0.000 0.005 0.995
L40.5 Arthropathic psoriasis
0.000 0.005 0.995
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.008 0.992
J22 Unspecified acute lower respiratory infection
0.000 0.010 0.990
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.012 0.988
D50.8 Other iron deficiency anaemias
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.018 0.982
E05.9 Thyrotoxicosis, unspecified
0.000 0.019 0.981
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.023 0.977
M05 Seropositive rheumatoid arthritis
0.000 0.023 0.977
J30-J39 Other diseases of upper respiratory tract
0.000 0.034 0.966
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.039 0.961
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.041 0.959
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.043 0.957
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.046 0.954
J80 Adult respiratory distress syndrome
0.000 0.046 0.954
M07 Psoriatic and enteropathic arthropathies
0.000 0.052 0.948
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.054 0.946
J33 Nasal polyp
0.000 0.054 0.946
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.055 0.945
L20-L30 Dermatitis and eczema
0.000 0.055 0.945
E20-E35 Disorders of other endocrine glands
0.000 0.056 0.944
M35.3 Polymyalgia rheumatica
0.000 0.059 0.941
D50.9 Iron deficiency anaemia, unspecified
0.000 0.064 0.936
M35 Other systemic involvement of connective tissue
0.000 0.064 0.936
H04 Disorders of lachrymal system
0.000 0.067 0.933
J84 Other interstitial pulmonary diseases
0.000 0.069 0.931
H02 Other disorders of eyelid
0.000 0.070 0.930
E27 Other disorders of adrenal gland
0.000 0.071 0.929
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.072 0.928
N48 Other disorders of penis
0.925 0.075 0.000
M20-M25 Other joint disorders
0.000 0.075 0.925
N40-N51 Diseases of male genital organs
0.924 0.076 0.000
E50-E64 Other nutritional deficiencies
0.000 0.079 0.921
J32 Chronic sinusitis
0.000 0.081 0.919
N48.6 Balanitis xerotica obliterans
0.917 0.083 0.000
J33.0 Polyp of nasal cavity
0.000 0.083 0.917
E11 Non-insulin-dependent diabetes mellitus
0.000 0.085 0.915
M07.3 Other psoriatic arthropathies
0.000 0.089 0.911
E10.5 With peripheral circulatory complications
0.000 0.092 0.908
N50 Other disorders of male genital organs
0.907 0.093 0.000
N45 Orchitis and epididymitis
0.898 0.102 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.102 0.898
N50.8 Other specified disorders of male genital organs
0.897 0.103 0.000
E11.3 With ophthalmic complications
0.000 0.105 0.895
E27.1 Primary adrenocortical insufficiency
0.000 0.106 0.894
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.109 0.891
H02.1 Ectropion of eyelid
0.000 0.112 0.888
N41 Inflammatory diseases of prostate
0.881 0.119 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.880 0.120 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.122 0.878
N48.0 Leukoplakia of penis
0.877 0.123 0.000
E14 Unspecified diabetes mellitus
0.000 0.125 0.875
E10.4 With neurological complications
0.000 0.126 0.874
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.128 0.872
L29 Pruritus
0.000 0.130 0.870
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.131 0.869
J09-J18 Influenza and pneumonia
0.000 0.134 0.866
J35 Chronic diseases of tonsils and adenoids
0.000 0.138 0.862
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.141 0.859
H33 Retinal detachments and breaks
0.000 0.142 0.858
E70-E90 Metabolic disorders
0.000 0.151 0.849
E10.2 With renal complications
0.000 0.153 0.847
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.156 0.844
L57.0 Actinic keratosis
0.000 0.156 0.844
J35.0 Chronic tonsillitis
0.000 0.156 0.844
J32.9 Chronic sinusitis, unspecified
0.000 0.157 0.843
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.157 0.843
D51 Vitamin B12 deficiency anaemia
0.000 0.158 0.842
E55 Vitamin D deficiency
0.000 0.163 0.837
M35.0 Sicca syndrome [Sjogren]
0.000 0.167 0.833
L81 Other disorders of pigmentation
0.000 0.169 0.831
L85 Other epidermal thickening
0.000 0.173 0.827
D60-D64 Aplastic and other anaemias
0.000 0.181 0.819
H33.2 Serous retinal detachment
0.000 0.183 0.817
H04.2 Epiphora
0.000 0.185 0.815
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.185 0.815
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.188 0.812
J18 Pneumonia, organism unspecified
0.000 0.188 0.812
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.193 0.807
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.197 0.803
M60-M63 Disorders of muscles
0.000 0.199 0.801
N47 Redundant prepuce, phimosis and paraphimosis
0.800 0.200 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.200 0.799
J20 Acute bronchitis
0.000 0.202 0.798
L82 Seborrhoeic keratosis
0.000 0.202 0.798
E06 Thyroiditis
0.000 0.202 0.798
N48.8 Other specified disorders of penis
0.797 0.203 0.000
J18.9 Pneumonia, unspecified
0.000 0.206 0.794
H02.0 Entropion and trichiasis of eyelid
0.000 0.206 0.794
L81.4 Other melanin hyperpigmentation
0.000 0.206 0.794
L29.0 Pruritus ani
0.000 0.208 0.792
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.213 0.787
L83 Acanthosis nigricans
0.000 0.214 0.786
N50.9 Disorder of male genital organs, unspecified
0.786 0.214 0.000
N41.0 Acute prostatitis
0.785 0.215 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.216 0.784
E53 Deficiency of other B group vitamins
0.000 0.218 0.782
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.218 0.782
N41.9 Inflammatory disease of prostate, unspecified
0.781 0.219 0.000
D52 Folate deficiency anaemia
0.000 0.222 0.778
E55.9 Vitamin D deficiency, unspecified
0.000 0.224 0.776
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.224 0.776
J32.8 Other chronic sinusitis
0.000 0.224 0.776
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.227 0.773
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.228 0.772
L28 Lichen simplex chronicus and prurigo
0.000 0.229 0.771
J33.9 Nasal polyp, unspecified
0.000 0.230 0.770
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.232 0.768
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.234 0.766
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.234 0.766
D61 Other aplastic anaemias
0.000 0.238 0.762
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.241 0.759
M06.3 Rheumatoid nodule
0.000 0.242 0.758
E11.1 With ketoacidosis
0.000 0.242 0.758
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.242 0.758
J81 Pulmonary oedema
0.000 0.244 0.756
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.247 0.753
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.249 0.751
E86 Volume depletion
0.000 0.252 0.748
E27.8 Other specified disorders of adrenal gland
0.000 0.253 0.747
L93 Lupus erythematosus
0.000 0.253 0.747
E04 Other non-toxic goitre
0.000 0.256 0.744
J33.8 Other polyp of sinus
0.000 0.260 0.740
E14.3 With ophthalmic complications
0.000 0.261 0.739
N48.9 Disorder of penis, unspecified
0.738 0.262 0.000
H02.5 Other disorders affecting eyelid function
0.000 0.263 0.736
L80 Vitiligo
0.000 0.264 0.736
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.265 0.735
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.266 0.734
J32.0 Chronic maxillary sinusitis
0.000 0.266 0.734
D55-D59 Haemolytic anaemias
0.000 0.266 0.734
J14 Pneumonia due to Haemophilus influenzae
0.000 0.271 0.729
H55-H59 Other disorders of eye and adnexa
0.000 0.271 0.729
H53-H54 Visual disturbances and blindness
0.000 0.272 0.728
M31 Other necrotising vasculopathies
0.000 0.273 0.727
M34 Systemic sclerosis
0.000 0.277 0.723
D61.9 Aplastic anaemia, unspecified
0.000 0.278 0.722
D53 Other nutritional anaemias
0.000 0.278 0.722
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.721 0.279 0.000
H33.3 Retinal breaks without detachment
0.000 0.279 0.721
H34 Retinal vascular occlusions
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.283 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
M12 Other specific arthropathies
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.715
L98.0 Pyogenic granuloma
0.000 0.286 0.714
D50.1 Sideropenic dysphagia
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
J21 Acute bronchiolitis
0.000 0.287 0.713
E27.9 Disorder of adrenal gland, unspecified
0.000 0.287 0.713
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.288 0.712
E14.9 Without complications
0.000 0.288 0.712
L20 Atopic dermatitis
0.000 0.290 0.710
L30 Other dermatitis
0.000 0.293 0.707
H05 Disorders of orbit
0.000 0.296 0.704
E07 Other disorders of thyroid
0.000 0.296 0.704
H02.4 Ptosis of eyelid
0.000 0.297 0.703
E65-E68 Obesity and other hyperalimentation
0.000 0.299 0.701
M05.8 Other seropositive rheumatoid arthritis
0.000 0.300 0.700
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.300 0.700
M05.2 Rheumatoid vasculitis
0.000 0.300 0.700
M05.1 Rheumatoid lung disease
0.000 0.300 0.700
M05.0 Felty's syndrome
0.000 0.300 0.700
L40.0 Psoriasis vulgaris
0.000 0.300 0.699
E29 Testicular dysfunction
0.000 0.302 0.698
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.303 0.697
H02.6 Xanthelasma of eyelid
0.000 0.303 0.697
L42 Pityriasis rosea
0.000 0.305 0.695
M14 Arthropathies in other diseases classified elsewhere
0.000 0.305 0.695
L85.8 Other specified epidermal thickening
0.000 0.305 0.695
E11.2 With renal complications
0.000 0.311 0.689
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.311 0.689
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.311 0.689
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.311 0.689
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.311 0.689
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.311 0.689
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.311 0.689
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.311 0.689
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.311 0.689
E10.6 With other specified complications
0.000 0.312 0.688
E23 Hypofunction and other disorders of pituitary gland
0.000 0.312 0.688
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.313 0.687
L87 Transepidermal elimination disorders
0.000 0.313 0.687
L88 Pyoderma gangrenosum
0.000 0.313 0.687
L86 Keratoderma in diseases classified elsewhere
0.000 0.313 0.687
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.314 0.686
L58 Radiodermatitis
0.000 0.314 0.686
L55 Sunburn
0.000 0.314 0.686
N48.2 Other inflammatory disorders of penis
0.685 0.315 0.000
H46 Optic neuritis
0.000 0.315 0.684
M10 Gout
0.000 0.316 0.684
E53.8 Deficiency of other specified B group vitamins
0.000 0.317 0.683
M06.4 Inflammatory polyarthropathy
0.000 0.319 0.681
J10 Influenza due to identified influenza virus
0.000 0.320 0.680
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.320 0.680
H04.9 Disorder of lachrymal system, unspecified
0.000 0.320 0.680
M07.6 Other enteropathic arthropathies
0.000 0.320 0.679
M07.5 Arthropathy in ulcerative colitis
0.000 0.320 0.679
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.320 0.679
M07.2 Psoriatic spondylitis
0.000 0.320 0.679
M07.1 Arthritis mutilans
0.000 0.320 0.679
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.320 0.679
E28 Ovarian dysfunction
0.000 0.321 0.679
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.322 0.678
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.322 0.678
J33.1 Polypoid sinus degeneration
0.000 0.322 0.678
L10-L14 Bullous disorders
0.000 0.322 0.678
N41.1 Chronic prostatitis
0.678 0.322 0.000
L25 Unspecified contact dermatitis
0.000 0.323 0.677
L24 Irritant contact dermatitis
0.000 0.323 0.677
L23 Allergic contact dermatitis
0.000 0.323 0.677
L21 Seborrhoeic dermatitis
0.000 0.323 0.677
L26 Exfoliative dermatitis
0.000 0.323 0.677
L22 Diaper [napkin] dermatitis
0.000 0.323 0.677
E73 Lactose intolerance
0.000 0.323 0.677
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.323 0.677
E32 Diseases of thymus
0.000 0.323 0.677
E31 Polyglandular dysfunction
0.000 0.323 0.677
E30 Disorders of puberty, not elsewhere classified
0.000 0.323 0.677
E25 Adrenogenital disorders
0.000 0.323 0.677
E20 Hypoparathyroidism
0.000 0.323 0.677
H02.9 Disorder of eyelid, unspecified
0.000 0.324 0.676
L94 Other localised connective tissue disorders
0.000 0.325 0.675
M11 Other crystal arthropathies
0.000 0.325 0.674
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.329 0.671
M35.8 Other specified systemic involvement of connective tissue
0.000 0.329 0.671
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.329 0.671
M35.5 Multifocal fibrosclerosis
0.000 0.329 0.671
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.329 0.671
M35.2 Behcet's disease
0.000 0.329 0.671
M35.1 Other overlap syndromes
0.000 0.329 0.671
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.329 0.670
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.330 0.670
H33.4 Traction detachment of retina
0.000 0.331 0.669
H04.8 Other disorders of lachrymal system
0.000 0.331 0.669
H04.6 Other changes in lachrymal passages
0.000 0.331 0.669
H04.0 Dacryoadenitis
0.000 0.331 0.669
L29.2 Pruritus vulvae
0.000 0.331 0.669
J84.8 Other specified interstitial pulmonary diseases
0.000 0.332 0.668
J84.0 Alveolar and parietoalveolar conditions
0.000 0.332 0.668
M35.7 Hypermobility syndrome
0.000 0.333 0.667
E26 Hyperaldosteronism
0.000 0.333 0.667
N50.0 Atrophy of testis
0.667 0.333 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.333 0.667
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.333 0.667
M62 Other disorders of muscle
0.000 0.334 0.666
E27.5 Adrenomedullary hyperfunction
0.000 0.334 0.666
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.334 0.666
E27.2 Addisonian crisis
0.000 0.334 0.666
E27.0 Other adrenocortical overactivity
0.000 0.334 0.666
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.334 0.666
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.334 0.666
L57.5 Actinic granuloma
0.000 0.334 0.666
L57.3 Poikiloderma of Civatte
0.000 0.334 0.666
L57.2 Cutis rhomboidalis nuchae
0.000 0.334 0.666
L57.1 Actinic reticuloid
0.000 0.334 0.666
L27 Dermatitis due to substances taken internally
0.000 0.335 0.665
L29.9 Pruritus, unspecified
0.000 0.335 0.665
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.336 0.664
H02.3 Blepharochalasis
0.000 0.336 0.664
N48.5 Ulcer of penis
0.663 0.337 0.000
N48.3 Priapism
0.663 0.337 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.337 0.663
J32.4 Chronic pansinusitis
0.000 0.337 0.663
N51 Disorders of male genital organs in diseases classified elsewhere
0.662 0.337 0.000
N44 Torsion of testis
0.662 0.337 0.000
E11.8 With unspecified complications
0.000 0.337 0.662
M32 Systemic lupus erythematosus
0.000 0.339 0.661
L85.9 Epidermal thickening, unspecified
0.000 0.339 0.661
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.340 0.660
E63 Other nutritional deficiencies
0.000 0.340 0.660
E56 Other vitamin deficiencies
0.000 0.340 0.660
E51 Thiamine deficiency
0.000 0.340 0.660
E50 Vitamin A deficiency
0.000 0.340 0.660
E60 Dietary zinc deficiency
0.000 0.340 0.660
E59 Dietary selenium deficiency
0.000 0.340 0.660
E58 Dietary calcium deficiency
0.000 0.340 0.660
E54 Ascorbic acid deficiency
0.000 0.340 0.660
E52 Niacin deficiency [pellagra]
0.000 0.340 0.660
H04.4 Chronic inflammation of lachrymal passages
0.000 0.340 0.660
E11.4 With neurological complications
0.000 0.340 0.660
D68 Other coagulation defects
0.000 0.340 0.660
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.341 0.659
J32.3 Chronic sphenoidal sinusitis
0.000 0.341 0.659
L43 Lichen planus
0.000 0.342 0.658
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.342 0.657
E06.3 Autoimmune thyroiditis
0.000 0.343 0.657
J20.9 Acute bronchitis, unspecified
0.000 0.343 0.657
E11.7 With multiple complications
0.000 0.344 0.656
E88 Other metabolic disorders
0.000 0.345 0.655
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.346 0.654
J32.1 Chronic frontal sinusitis
0.000 0.346 0.654
M07.38 Other psoriatic arthropathies (Other)
0.000 0.347 0.653
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.347 0.653
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.347 0.653
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.347 0.653
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.347 0.653
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.347 0.653
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.347 0.653
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.347 0.653
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.652 0.348 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.349 0.650
L28.0 Lichen simplex chronicus
0.000 0.353 0.647
E89.0 Postprocedural hypothyroidism
0.000 0.354 0.646
M00-M03 Infectious arthropathies
0.000 0.355 0.645
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.356 0.644
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.356 0.644
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.356 0.644
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.356 0.644
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.356 0.644
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.356 0.644
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.356 0.644
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.356 0.644
J31.2 Chronic pharyngitis
0.000 0.357 0.643
N48.4 Impotence of organic origin
0.642 0.358 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.362 0.638
E24 Cushing's syndrome
0.000 0.366 0.634
N46 Male infertility
0.632 0.368 0.000
N41.8 Other inflammatory diseases of prostate
0.631 0.369 0.000
N41.3 Prostatocystitis
0.631 0.369 0.000
N41.2 Abscess of prostate
0.631 0.369 0.000
E05.8 Other thyrotoxicosis
0.000 0.369 0.631
E40-E46 Malnutrition
0.000 0.370 0.630
J32.2 Chronic ethmoidal sinusitis
0.000 0.373 0.627
E14.8 With unspecified complications
0.000 0.373 0.627
E14.7 With multiple complications
0.000 0.373 0.627
E14.6 With other specified complications
0.000 0.373 0.627
E14.5 With peripheral circulatory complications
0.000 0.373 0.627
E14.4 With neurological complications
0.000 0.373 0.627
E14.2 Withrenal complications
0.000 0.373 0.627
E14.1 With ketoacidosis
0.000 0.373 0.627
E14.0 With coma
0.000 0.373 0.627
M91-M94 Chondropathies
0.000 0.373 0.627
L29.8 Other pruritus
0.000 0.376 0.624
L29.3 Anogenital pruritus, unspecified
0.000 0.376 0.624
L29.1 Pruritus scroti
0.000 0.376 0.624
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.377 0.623
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.377 0.623
L98.5 Mucinosis of skin
0.000 0.377 0.623
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.377 0.623
L98.1 Factitial dermatitis
0.000 0.377 0.623
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.379 0.621
J09 Influenza due to certain identified influenza virus
0.000 0.379 0.621
D52.9 Folate deficiency anaemia, unspecified
0.000 0.380 0.620
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.382 0.618
E04.9 Non-toxic goitre, unspecified
0.000 0.385 0.615
J11 Influenza, virus not identified
0.000 0.387 0.613
M33 Dermatopolymyositis
0.000 0.389 0.611
E22 Hyperfunction of pituitary gland
0.000 0.390 0.610
E84 Cystic fibrosis
0.000 0.391 0.609
E79 Disorders of purine and pyrimidine metabolism
0.000 0.391 0.609
E77 Disorders of glycoprotein metabolism
0.000 0.391 0.609
E76 Disorders of glycosaminoglycan metabolism
0.000 0.391 0.609
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.391 0.609
E72 Other disorders of amino-acid metabolism
0.000 0.391 0.609
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.391 0.609
E70 Disorders of aromatic amino-acid metabolism
0.000 0.391 0.609
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.391 0.609
J37 Chronic laryngitis and laryngotracheitis
0.000 0.394 0.605
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.395 0.605
N42 Other disorders of prostate
0.605 0.395 0.000
M80-M85 Disorders of bone density and structure
0.000 0.396 0.604
M30 Polyarteritis nodosa and related conditions
0.000 0.396 0.604
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.396 0.604
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.396 0.604
D51.2 Transcobalamin II deficiency
0.000 0.396 0.604
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.396 0.604
E74 Other disorders of carbohydrate metabolism
0.000 0.399 0.601
E55.0 Rickets, active
0.000 0.400 0.600
H10-H13 Disorders of conjunctiva
0.000 0.402 0.598
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.402 0.598
H01 Other inflammation of eyelid
0.000 0.403 0.597
H02.2 Lagophthalmos
0.000 0.403 0.597
J17 Pneumonia in diseases classified elsewhere
0.000 0.403 0.596
L57.4 Cutis laxa senilis
0.000 0.404 0.596
L81.7 Pigmented purpuric dermatosis
0.000 0.404 0.595
L81.6 Other disorders of diminished melanin formation
0.000 0.404 0.595
L81.5 Leukoderma, not elsewhere classified
0.000 0.404 0.595
L81.3 Cafe au lait spots
0.000 0.404 0.595
L81.2 Freckles
0.000 0.404 0.595
L81.1 Chloasma
0.000 0.404 0.595
L81.0 Postinflammatory hyperpigmentation
0.000 0.404 0.595
L93.0 Discoid lupus erythematosus
0.000 0.405 0.595
E85 Amyloidosis
0.000 0.405 0.594
H16 Keratitis
0.000 0.405 0.594
D64 Other anaemias
0.000 0.406 0.594
M31.3 Wegener's granulomatosis
0.000 0.407 0.593
L85.3 Xerosis cutis
0.000 0.407 0.593
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.407 0.593
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.407 0.593
L85.0 Acquired ichthyosis
0.000 0.407 0.593
E61 Deficiency of other nutrient elements
0.000 0.408 0.592
E78.2 Mixed hyperlipidaemia
0.000 0.409 0.591
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.409 0.591
N43 Hydrocele and spermatocele
0.590 0.410 0.000
E03.8 Other specified hypothyroidism
0.000 0.411 0.588
E34 Other endocrine disorders
0.000 0.412 0.588
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.413 0.587
H00 Hordeolum and chalazion
0.001 0.413 0.586
E11.0 With coma
0.000 0.414 0.586
M06.34 Rheumatoid nodule (Hand)
0.000 0.415 0.585
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.418 0.582
J18.2 Hypostatic pneumonia, unspecified
0.000 0.418 0.582
D86 Sarcoidosis
0.000 0.420 0.580
H55 Nystagmus and other irregular eye movements
0.000 0.421 0.579
M34.9 Systemic sclerosis, unspecified
0.000 0.422 0.578
J35.2 Hypertrophy of adenoids
0.000 0.423 0.577
E04.2 Non-toxic multinodular goitre
0.000 0.424 0.576
N49.2 Inflammatory disorders of scrotum
0.576 0.424 0.000
J39 Other diseases of upper respiratory tract
0.000 0.425 0.575
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.426 0.574
M61 Calcification and ossification of muscle
0.000 0.426 0.574
M60 Myositis
0.000 0.426 0.574
J00-J06 Acute upper respiratory infections
0.000 0.426 0.574
J20.8 Acute bronchitis due to other specified organisms
0.000 0.428 0.572
J20.7 Acute bronchitis due to echovirus
0.000 0.428 0.572
J20.6 Acute bronchitis due to rhinovirus
0.000 0.428 0.572
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.428 0.572
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.428 0.572
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.428 0.572
J20.2 Acute bronchitis due to streptococcus
0.000 0.428 0.572
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.428 0.572
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.428 0.572
E06.5 Other chronic thyroiditis
0.000 0.428 0.572
E06.4 Drug-induced thyroiditis
0.000 0.428 0.572
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.428 0.572
E06.1 Subacute thyroiditis
0.000 0.428 0.572
E06.0 Acute thyroiditis
0.000 0.428 0.572
M80 Osteoporosis with pathological fracture
0.000 0.429 0.571
M86-M90 Other osteopathies
0.000 0.429 0.571
M62.8 Other specified disorders of muscle
0.000 0.430 0.570
L30.8 Other specified dermatitis
0.000 0.433 0.567
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.434 0.566
L84 Corns and callosities
0.000 0.434 0.565
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.436 0.564
E06.9 Thyroiditis, unspecified
0.000 0.436 0.564
J18.1 Lobar pneumonia, unspecified
0.000 0.436 0.564
H50 Other strabismus
0.000 0.437 0.563
H33.1 Retinoschisis and retinal cysts
0.000 0.437 0.563
H35 Other retinal disorders
0.000 0.438 0.562

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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