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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28371355
log Bayes Factor = 20.3786
Chromosome 6   position 32,710,557  (GRCh37) Explore rs28371355 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.003 0.997
Chapter X Diseases of the respiratory system
0.000 0.004 0.996
E03 Other hypothyroidism
0.000 0.006 0.994
M35.3 Polymyalgia rheumatica
0.000 0.007 0.993
M35 Other systemic involvement of connective tissue
0.000 0.007 0.993
E03.9 Hypothyroidism, unspecified
0.000 0.008 0.992
J20-J22 Other acute lower respiratory infections
0.000 0.011 0.989
M20-M25 Other joint disorders
0.000 0.011 0.989
L20-L30 Dermatitis and eczema
0.000 0.013 0.987
C44 Other malignant neoplasms of skin
0.000 0.014 0.986
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.018 0.982
J22 Unspecified acute lower respiratory infection
0.000 0.018 0.982
C44.7 Skin of lower limb, including hip
0.000 0.019 0.981
J30-J39 Other diseases of upper respiratory tract
0.000 0.020 0.980
E10.3 With ophthalmic complications
0.000 0.020 0.980
L40-L45 Papulosquamous disorders
0.000 0.020 0.980
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.023 0.977
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.026 0.974
L40 Psoriasis
0.000 0.027 0.973
E10.1 With ketoacidosis
0.000 0.027 0.973
L40.5 Arthropathic psoriasis
0.000 0.030 0.970
C44.3 Skin of other and unspecified parts of face
0.000 0.030 0.970
Chapter II Neoplasms
0.000 0.033 0.967
M07 Psoriatic and enteropathic arthropathies
0.000 0.033 0.967
L29 Pruritus
0.000 0.036 0.964
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.038 0.962
M05 Seropositive rheumatoid arthritis
0.000 0.041 0.959
E05.9 Thyrotoxicosis, unspecified
0.000 0.044 0.956
M35.0 Sicca syndrome [Sjogren]
0.000 0.054 0.946
Chapter VII Diseases of the eye and adnexa
0.000 0.055 0.945
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.055 0.945
M07.3 Other psoriatic arthropathies
0.000 0.056 0.944
J35 Chronic diseases of tonsils and adenoids
0.000 0.057 0.943
J33 Nasal polyp
0.000 0.064 0.936
J35.0 Chronic tonsillitis
0.000 0.064 0.936
L57.0 Actinic keratosis
0.000 0.065 0.935
H04 Disorders of lachrymal system
0.000 0.068 0.932
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.071 0.929
H02 Other disorders of eyelid
0.000 0.080 0.920
L29.0 Pruritus ani
0.000 0.084 0.916
J33.0 Polyp of nasal cavity
0.000 0.086 0.914
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.094 0.906
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.098 0.902
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.101 0.899
G35 Multiple sclerosis
0.000 0.102 0.898
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.109 0.891
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.113 0.887
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.114 0.886
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.114 0.886
L29.9 Pruritus, unspecified
0.000 0.117 0.883
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
Chapter VI Diseases of the nervous system
0.000 0.120 0.880
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.122 0.878
H02.0 Entropion and trichiasis of eyelid
0.000 0.124 0.876
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.124 0.875
C44.6 Skin of upper limb, including shoulder
0.000 0.126 0.874
J95-J99 Other diseases of the respiratory system
0.000 0.130 0.870
H02.1 Ectropion of eyelid
0.000 0.134 0.866
C18 Malignant neoplasm of colon
0.000 0.135 0.865
M34 Systemic sclerosis
0.000 0.136 0.864
C15-C26 Malignant neoplasms of digestive organs
0.000 0.139 0.861
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.141 0.859
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.144 0.856
Chapter V Mental and behavioural disorders
0.000 0.153 0.847
H30-H36 Disorders of choroid and retina
0.000 0.170 0.830
C64-C68 Malignant neoplasms of urinary tract
0.000 0.171 0.829
C44.0 Skin of lip
0.000 0.171 0.829
J32 Chronic sinusitis
0.000 0.172 0.828
Chapter VIII Diseases of the ear and mastoid process
0.000 0.173 0.827
C18.7 Sigmoid colon
0.000 0.173 0.827
H04.2 Epiphora
0.000 0.179 0.821
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.182 0.818
J20 Acute bronchitis
0.000 0.183 0.817
H36 Retinal disorders in diseases classified elsewhere
0.000 0.186 0.814
L30 Other dermatitis
0.000 0.188 0.812
H53-H54 Visual disturbances and blindness
0.000 0.190 0.810
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.191 0.809
M31 Other necrotising vasculopathies
0.000 0.192 0.808
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.194 0.806
G30-G32 Other degenerative diseases of the nervous system
0.000 0.195 0.805
H36.0 Diabetic retinopathy
0.000 0.197 0.803
E50-E64 Other nutritional deficiencies
0.000 0.198 0.802
L27 Dermatitis due to substances taken internally
0.000 0.198 0.802
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.198 0.802
C44.2 Skin of ear and external auricular canal
0.000 0.202 0.798
C44.1 Skin of eyelid, including canthus
0.000 0.203 0.797
J98 Other respiratory disorders
0.000 0.206 0.794
M06.0 Seronegative rheumatoid arthritis
0.000 0.206 0.794
L85 Other epidermal thickening
0.000 0.207 0.793
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.208 0.792
J38.7 Other diseases of larynx
0.000 0.209 0.791
L82 Seborrhoeic keratosis
0.000 0.215 0.785
H65-H75 Diseases of middle ear and mastoid
0.000 0.217 0.783
H05 Disorders of orbit
0.000 0.222 0.778
M34.9 Systemic sclerosis, unspecified
0.000 0.225 0.775
E10.2 With renal complications
0.000 0.229 0.771
F30-F39 Mood [affective] disorders
0.000 0.230 0.770
J00-J06 Acute upper respiratory infections
0.000 0.231 0.769
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.232 0.768
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.232 0.768
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.235 0.765
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.235 0.765
C18.4 Transverse colon
0.000 0.235 0.765
H72 Perforation of tympanic membrane
0.000 0.237 0.763
C18.2 Ascending colon
0.000 0.241 0.759
C34 Malignant neoplasm of bronchus and lung
0.000 0.243 0.757
M35.7 Hypermobility syndrome
0.000 0.243 0.757
M22 Disorders of patella
0.000 0.247 0.753
E13 Other specified diabetes mellitus
0.000 0.249 0.751
M00-M03 Infectious arthropathies
0.000 0.250 0.750
L93 Lupus erythematosus
0.000 0.252 0.748
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.254 0.746
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.259 0.741
J32.8 Other chronic sinusitis
0.000 0.259 0.740
E04 Other non-toxic goitre
0.000 0.261 0.739
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.262 0.738
H02.5 Other disorders affecting eyelid function
0.000 0.263 0.737
L28 Lichen simplex chronicus and prurigo
0.000 0.266 0.734
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.267 0.733
C18.3 Hepatic flexure
0.000 0.267 0.733
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.269 0.731
H04.8 Other disorders of lachrymal system
0.000 0.274 0.726
L08 Other local infections of skin and subcutaneous tissue
0.000 0.274 0.726
H53 Visual disturbances
0.000 0.276 0.724
J38.1 Polyp of vocal cord and larynx
0.000 0.277 0.723
M31.3 Wegener's granulomatosis
0.000 0.279 0.721
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.280 0.720
C44.4 Skin of scalp and neck
0.000 0.281 0.719
J33.9 Nasal polyp, unspecified
0.000 0.282 0.718
L83 Acanthosis nigricans
0.000 0.282 0.718
J38.4 Oedema of larynx
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.716
M06.3 Rheumatoid nodule
0.000 0.284 0.716
M14 Arthropathies in other diseases classified elsewhere
0.000 0.285 0.715
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.287 0.713
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
E03.1 Congenital hypothyroidism without goitre
0.000 0.288 0.712
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.288 0.712
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.288 0.712
M35.8 Other specified systemic involvement of connective tissue
0.000 0.288 0.712
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.288 0.712
M35.5 Multifocal fibrosclerosis
0.000 0.288 0.712
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.288 0.712
M35.2 Behcet's disease
0.000 0.288 0.712
M35.1 Other overlap syndromes
0.000 0.288 0.712
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.288 0.712
D00-D09 In situ neoplasms
0.000 0.289 0.711
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.290 0.710
J21 Acute bronchiolitis
0.000 0.291 0.709
M06.4 Inflammatory polyarthropathy
0.000 0.291 0.709
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.291 0.709
M32 Systemic lupus erythematosus
0.000 0.291 0.709
H02.6 Xanthelasma of eyelid
0.000 0.291 0.709
L25 Unspecified contact dermatitis
0.000 0.292 0.708
L24 Irritant contact dermatitis
0.000 0.292 0.708
L23 Allergic contact dermatitis
0.000 0.292 0.708
L21 Seborrhoeic dermatitis
0.000 0.292 0.708
L26 Exfoliative dermatitis
0.000 0.292 0.708
L22 Diaper [napkin] dermatitis
0.000 0.292 0.708
C44.8 Overlapping lesion of skin
0.000 0.293 0.707
C18.6 Descending colon
0.000 0.295 0.705
E05.5 Thyroid crisis or storm
0.000 0.296 0.704
E05.4 Thyrotoxicosis factitia
0.000 0.296 0.704
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.296 0.704
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.296 0.704
C18.5 Splenic flexure
0.000 0.296 0.704
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.296 0.704
N48 Other disorders of penis
0.704 0.296 0.000
L44 Other papulosquamous disorders
0.000 0.297 0.702
L41 Parapsoriasis
0.000 0.297 0.702
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.297 0.702
Chapter I Certain infectious and parasitic diseases
0.000 0.297 0.703
J32.0 Chronic maxillary sinusitis
0.000 0.298 0.702
N48.6 Balanitis xerotica obliterans
0.701 0.299 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.299 0.701
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.300 0.700
L58 Radiodermatitis
0.000 0.300 0.700
L55 Sunburn
0.000 0.300 0.700
C34.9 Bronchus or lung, unspecified
0.000 0.300 0.700
H72.0 Central perforation of tympanic membrane
0.000 0.300 0.700
M11 Other crystal arthropathies
0.000 0.301 0.699
G30 Alzheimer's disease
0.000 0.301 0.699
L40.8 Other psoriasis
0.000 0.302 0.698
L40.4 Guttate psoriasis
0.000 0.302 0.698
L40.3 Pustulosis palmaris et plantaris
0.000 0.302 0.698
L40.2 Acrodermatitis continua
0.000 0.302 0.698
L40.1 Generalised pustular psoriasis
0.000 0.302 0.698
C18.1 Appendix
0.000 0.302 0.698
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.306 0.694
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.306 0.694
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.306 0.694
M07.6 Other enteropathic arthropathies
0.000 0.307 0.693
M07.5 Arthropathy in ulcerative colitis
0.000 0.307 0.693
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.307 0.693
M07.2 Psoriatic spondylitis
0.000 0.307 0.693
M07.1 Arthritis mutilans
0.000 0.307 0.693
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.307 0.693
J20.9 Acute bronchitis, unspecified
0.000 0.307 0.693
L29.3 Anogenital pruritus, unspecified
0.000 0.308 0.691
L29.1 Pruritus scroti
0.000 0.308 0.691
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.309 0.691
C73 Malignant neoplasm of thyroid gland
0.000 0.310 0.690
J80 Adult respiratory distress syndrome
0.000 0.310 0.690
C34.1 Upper lobe, bronchus or lung
0.000 0.310 0.690
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.310 0.690
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.310 0.690
L57.5 Actinic granuloma
0.000 0.310 0.690
L57.4 Cutis laxa senilis
0.000 0.310 0.690
L57.3 Poikiloderma of Civatte
0.000 0.310 0.690
L57.2 Cutis rhomboidalis nuchae
0.000 0.310 0.690
L57.1 Actinic reticuloid
0.000 0.310 0.690
J98.4 Other disorders of lung
0.000 0.311 0.689
C81 Hodgkin's disease
0.000 0.312 0.688
M05.8 Other seropositive rheumatoid arthritis
0.000 0.313 0.687
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.313 0.687
M05.2 Rheumatoid vasculitis
0.000 0.313 0.687
M05.1 Rheumatoid lung disease
0.000 0.313 0.687
M05.0 Felty's syndrome
0.000 0.313 0.687
L20 Atopic dermatitis
0.000 0.314 0.686
J81 Pulmonary oedema
0.000 0.314 0.686
H04.9 Disorder of lachrymal system, unspecified
0.000 0.316 0.684
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.317 0.683
F31 Bipolar affective disorder
0.000 0.318 0.682
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.319 0.681
L29.2 Pruritus vulvae
0.000 0.320 0.680
C66 Malignant neoplasm of ureter
0.000 0.321 0.679
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.321 0.679
F60-F69 Disorders of adult personality and behaviour
0.000 0.322 0.678
C18.0 Caecum
0.000 0.323 0.677
M07.38 Other psoriatic arthropathies (Other)
0.000 0.323 0.677
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.323 0.677
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.323 0.677
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.323 0.677
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.323 0.677
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.323 0.677
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.323 0.677
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.323 0.677
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.323 0.677
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.323 0.676
H02.9 Disorder of eyelid, unspecified
0.000 0.325 0.675
L29.8 Other pruritus
0.000 0.325 0.675
N40-N51 Diseases of male genital organs
0.674 0.326 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.328 0.672
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.328 0.672
J33.1 Polypoid sinus degeneration
0.000 0.329 0.671
L85.9 Epidermal thickening, unspecified
0.000 0.329 0.671
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.329 0.671
D06 Carcinoma in situ of cervix uteri
0.000 0.329 0.671
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.329 0.671
H53.0 Amblyopia ex anopsia
0.000 0.330 0.670
J00 Acute nasopharyngitis [common cold]
0.000 0.331 0.669
H55-H59 Other disorders of eye and adnexa
0.000 0.332 0.668
H04.6 Other changes in lachrymal passages
0.000 0.332 0.668
H04.0 Dacryoadenitis
0.000 0.332 0.668
M91-M94 Chondropathies
0.000 0.333 0.667
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.334 0.666
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.334 0.666
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.334 0.666
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.334 0.666
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.334 0.666
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.334 0.666
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.334 0.666
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.334 0.666
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.334 0.666
J38.2 Nodules of vocal cords
0.000 0.334 0.666
M30 Polyarteritis nodosa and related conditions
0.000 0.334 0.666
L42 Pityriasis rosea
0.000 0.334 0.666
N48.0 Leukoplakia of penis
0.666 0.334 0.000
L85.8 Other specified epidermal thickening
0.000 0.335 0.665
E07 Other disorders of thyroid
0.000 0.336 0.664
F32 Depressive episode
0.000 0.336 0.664
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.336 0.664
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.338 0.662
M22.2 Patellofemoral disorders
0.000 0.338 0.662
H66 Suppurative and unspecified otitis media
0.000 0.339 0.661
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.339 0.661
L40.0 Psoriasis vulgaris
0.000 0.339 0.661
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.340 0.660
L10-L14 Bullous disorders
0.000 0.340 0.660
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.341 0.659
E10.4 With neurological complications
0.000 0.341 0.659
L84 Corns and callosities
0.000 0.341 0.659
B35-B49 Mycoses
0.000 0.341 0.659
L81 Other disorders of pigmentation
0.000 0.342 0.658
N47 Redundant prepuce, phimosis and paraphimosis
0.657 0.343 0.000
L30.8 Other specified dermatitis
0.000 0.344 0.656
J84 Other interstitial pulmonary diseases
0.000 0.344 0.656
J98.1 Pulmonary collapse
0.000 0.345 0.655
H53.9 Visual disturbance, unspecified
0.000 0.345 0.655
H02.2 Lagophthalmos
0.000 0.346 0.654
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.346 0.654
H04.1 Other disorders of lachrymal gland
0.000 0.347 0.653
E53 Deficiency of other B group vitamins
0.000 0.348 0.652
C26.0 Intestinal tract, part unspecified
0.000 0.349 0.651
E11 Non-insulin-dependent diabetes mellitus
0.000 0.349 0.651
B37.8 Candidiasis of other sites
0.000 0.349 0.651
E55 Vitamin D deficiency
0.000 0.350 0.650
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.351 0.649
B37 Candidiasis
0.000 0.352 0.647
L93.0 Discoid lupus erythematosus
0.000 0.354 0.646
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.354 0.646
E20-E35 Disorders of other endocrine glands
0.000 0.357 0.643
D06.9 Cervix, unspecified
0.000 0.357 0.643
J38.5 Laryngeal spasm
0.000 0.358 0.642
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.358 0.642
L40.9 Psoriasis, unspecified
0.000 0.358 0.642
J37 Chronic laryngitis and laryngotracheitis
0.000 0.359 0.641
E04.2 Non-toxic multinodular goitre
0.000 0.360 0.640
E05.8 Other thyrotoxicosis
0.000 0.361 0.639
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.361 0.639
L87 Transepidermal elimination disorders
0.000 0.361 0.639
L88 Pyoderma gangrenosum
0.000 0.361 0.639
L86 Keratoderma in diseases classified elsewhere
0.000 0.361 0.639
L80 Vitiligo
0.000 0.361 0.639
H80-H83 Diseases of inner ear
0.000 0.362 0.638
H05.0 Acute inflammation of orbit
0.000 0.363 0.636
H04.4 Chronic inflammation of lachrymal passages
0.000 0.364 0.636
G36 Other acute disseminated demyelination
0.000 0.364 0.636
J38.6 Stenosis of larynx
0.000 0.365 0.635
E14 Unspecified diabetes mellitus
0.000 0.368 0.632
N45 Orchitis and epididymitis
0.632 0.368 0.000
C81.9 Hodgkin's disease, unspecified
0.000 0.369 0.630
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.369 0.630
E06 Thyroiditis
0.000 0.370 0.630
D50-D53 Nutritional anaemias
0.000 0.372 0.628
F20 Schizophrenia
0.000 0.373 0.627
C43 Malignant melanoma of skin
0.000 0.373 0.627
L30.9 Dermatitis, unspecified
0.000 0.373 0.627
F22 Persistent delusional disorders
0.000 0.374 0.626
M60-M63 Disorders of muscles
0.000 0.375 0.625
J96 Respiratory failure, not elsewhere classified
0.000 0.376 0.624
E65-E68 Obesity and other hyperalimentation
0.000 0.376 0.624
G30.9 Alzheimer's disease, unspecified
0.000 0.377 0.623
G37 Other demyelinating diseases of central nervous system
0.000 0.377 0.623
F31.9 Bipolar affective disorder, unspecified
0.000 0.380 0.620
C18.8 Overlapping lesion of colon
0.000 0.380 0.620
M34.8 Other forms of systemic sclerosis
0.000 0.380 0.620
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.380 0.620
M34.1 CR(E)ST syndrome
0.000 0.380 0.620
M34.0 Progressive systemic sclerosis
0.000 0.380 0.620
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.380 0.620
L94 Other localised connective tissue disorders
0.000 0.383 0.617
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.383 0.616
J01 Acute sinusitis
0.000 0.387 0.613
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.387 0.613
E27 Other disorders of adrenal gland
0.000 0.389 0.611
H05.2 Exophthalmic conditions
0.000 0.389 0.610
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.390 0.609
J98.9 Respiratory disorder, unspecified
0.000 0.391 0.609
J36 Peritonsillar abscess
0.000 0.391 0.609
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.392 0.607
F70-F79 Mental retardation
0.000 0.392 0.607
M33 Dermatopolymyositis
0.000 0.393 0.607
D50 Iron deficiency anaemia
0.000 0.395 0.605
N48.8 Other specified disorders of penis
0.605 0.395 0.000
H02.4 Ptosis of eyelid
0.000 0.399 0.601
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.399 0.600
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.400 0.600
M80-M85 Disorders of bone density and structure
0.001 0.401 0.599
J34 Other disorders of nose and nasal sinuses
0.000 0.401 0.599
H46 Optic neuritis
0.000 0.402 0.597
F25 Schizoaffective disorders
0.000 0.403 0.597
H01 Other inflammation of eyelid
0.000 0.403 0.597
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.405 0.595
H30 Chorioretinal inflammation
0.000 0.405 0.595
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.405 0.595
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.405 0.594
H70 Mastoiditis and related conditions
0.000 0.406 0.594
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.594 0.406 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.406 0.594
J32.3 Chronic sphenoidal sinusitis
0.000 0.407 0.593
J32.1 Chronic frontal sinusitis
0.000 0.407 0.593
M10 Gout
0.000 0.407 0.593
C23 Malignant neoplasm of gallbladder
0.000 0.407 0.593
J38.0 Paralysis of vocal cords and larynx
0.000 0.408 0.592
N42 Other disorders of prostate
0.590 0.410 0.000
F01 Vascular dementia
0.000 0.411 0.589
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.411 0.589
F80-F89 Disorders of psychological development
0.000 0.412 0.588
C18.9 Colon, unspecified
0.000 0.413 0.587
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.413 0.587
L04 Acute lymphadenitis
0.000 0.413 0.587
L01 Impetigo
0.000 0.413 0.587
L00 Staphylococcal scalded skin syndrome
0.000 0.413 0.587
J20.8 Acute bronchitis due to other specified organisms
0.000 0.414 0.586
J20.7 Acute bronchitis due to echovirus
0.000 0.414 0.586
J20.6 Acute bronchitis due to rhinovirus
0.000 0.414 0.586
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.414 0.586
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.414 0.586
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.414 0.586
J20.2 Acute bronchitis due to streptococcus
0.000 0.414 0.586
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.414 0.586
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.414 0.586
D50.9 Iron deficiency anaemia, unspecified
0.000 0.416 0.584
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.416 0.583
E11.3 With ophthalmic complications
0.000 0.417 0.583
F00 Dementia in Alzheimer's disease
0.000 0.417 0.583
L30.5 Pityriasis alba
0.000 0.418 0.582
L30.4 Erythema intertrigo
0.000 0.418 0.582
L30.3 Infective dermatitis
0.000 0.418 0.582
L30.2 Cutaneous autosensitisation
0.000 0.418 0.582
L30.1 Dyshidrosis [pompholyx]
0.000 0.418 0.582
L30.0 Nummular dermatitis
0.000 0.418 0.582
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.418 0.582
C65 Malignant neoplasm of renal pelvis
0.000 0.419 0.581
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.420 0.580
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.420 0.580
C31 Malignant neoplasm of accessory sinuses
0.000 0.420 0.580
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.420 0.580
C33 Malignant neoplasm of trachea
0.000 0.420 0.580
M31.9 Necrotising vasculopathy, unspecified
0.000 0.421 0.579
M31.8 Other specified necrotising vasculopathies
0.000 0.421 0.579
M31.7 Microscopic polyangiitis
0.000 0.421 0.579
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.421 0.579
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.421 0.579
M31.2 Lethal midline granuloma
0.000 0.421 0.579
M31.1 Thrombotic microangiopathy
0.000 0.421 0.579
M31.0 Hypersensitivity angiitis
0.000 0.421 0.579
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.422 0.578
C74 Malignant neoplasm of adrenal gland
0.000 0.422 0.578
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.423 0.577
L98.0 Pyogenic granuloma
0.000 0.423 0.577
F60 Specific personality disorders
0.000 0.423 0.577
Chapter XXII Codes for special purposes
0.000 0.424 0.576
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.425 0.575
E63 Other nutritional deficiencies
0.000 0.425 0.575
E56 Other vitamin deficiencies
0.000 0.425 0.575
E51 Thiamine deficiency
0.000 0.425 0.575
E50 Vitamin A deficiency
0.000 0.425 0.575
E60 Dietary zinc deficiency
0.000 0.425 0.575
E59 Dietary selenium deficiency
0.000 0.425 0.575
E58 Dietary calcium deficiency
0.000 0.425 0.575
E54 Ascorbic acid deficiency
0.000 0.425 0.575
E52 Niacin deficiency [pellagra]
0.000 0.425 0.575
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.425 0.575
L27.8 Dermatitis due to other substances taken internally
0.000 0.425 0.575
L27.2 Dermatitis due to ingested food
0.000 0.425 0.575
C92 Myeloid leukaemia
0.000 0.425 0.575
E27.1 Primary adrenocortical insufficiency
0.000 0.426 0.574
E13.9 Without complications
0.000 0.427 0.573
L81.4 Other melanin hyperpigmentation
0.000 0.427 0.573
M00 Pyogenic arthritis
0.000 0.427 0.573
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.427 0.572
H53.1 Subjective visual disturbances
0.000 0.428 0.572
E04.9 Non-toxic goitre, unspecified
0.000 0.429 0.571
F05.9 Delirium, unspecified
0.000 0.430 0.570
J98.3 Compensatory emphysema
0.000 0.430 0.569
J98.2 Interstitial emphysema
0.000 0.430 0.569
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.430 0.569
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.430 0.569
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.430 0.569
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.430 0.569
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.430 0.569
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.430 0.569
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.430 0.569
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.430 0.569
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.430 0.570
L85.3 Xerosis cutis
0.000 0.431 0.569
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.431 0.569
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.431 0.569
L85.0 Acquired ichthyosis
0.000 0.431 0.569
N48.9 Disorder of penis, unspecified
0.568 0.432 0.000
F32.1 Moderate depressive episode
0.000 0.434 0.566
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.435 0.565
J04 Acute laryngitis and tracheitis
0.000 0.435 0.565
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.436 0.564
J02 Acute pharyngitis
0.000 0.436 0.564
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.439 0.561
H68 Eustachian salpingitis and obstruction
0.000 0.439 0.561
H67 Otitis media in diseases classified elsewhere
0.000 0.439 0.561

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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